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CAZyme Information: MGYG000002359_01617
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | Mycobacterium tuberculosis | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Actinobacteriota; Actinomycetia; Mycobacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis | |||||||||||
| CAZyme ID | MGYG000002359_01617 | |||||||||||
| CAZy Family | GT1 | |||||||||||
| CAZyme Description | putative glycosyltransferase | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 84434; End: 85678 Strand: + | |||||||||||
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| GT1 | 9 | 409 | 1.3e-38 | 0.9738219895287958 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| COG1819 | YjiC | 7.19e-109 | 1 | 412 | 2 | 401 | UDP:flavonoid glycosyltransferase YjiC, YdhE family [Carbohydrate transport and metabolism]. |
| cd03784 | GT1_Gtf-like | 1.75e-58 | 1 | 408 | 1 | 403 | UDP-glycosyltransferases and similar proteins. This family includes the Gtfs, a group of homologous glycosyltransferases involved in the final stages of the biosynthesis of antibiotics vancomycin and related chloroeremomycin. Gtfs transfer sugar moieties from an activated NDP-sugar donor to the oxidatively cross-linked heptapeptide core of vancomycin group antibiotics. The core structure is important for the bioactivity of the antibiotics. |
| TIGR04516 | glycosyl_450act | 3.06e-09 | 295 | 414 | 299 | 418 | glycosyltransferase, activator-dependent family. Many biosynthesis clusters for secondary metabolites feature a glycosyltransferase gene next to a P450 homolog, often with the P450 lacking a critical heme-binding Cys. These P540-derived sequences seem to be allosteric activators of glycosyltransferases such as the member of this family. This model describes a set of related glycosyltransferases, many of which can be recognized as activator-dependent from genomic context. |
| TIGR01426 | MGT | 2.83e-08 | 12 | 407 | 7 | 387 | glycosyltransferase, MGT family. This model describes the MGT (macroside glycosyltransferase) subfamily of the UDP-glucuronosyltransferase family. Members include a number of glucosyl transferases for macrolide antibiotic inactivation, but also include transferases of glucose-related sugars for macrolide antibiotic production. [Cellular processes, Toxin production and resistance] |
| pfam03033 | Glyco_transf_28 | 5.15e-04 | 3 | 86 | 1 | 86 | Glycosyltransferase family 28 N-terminal domain. The glycosyltransferase family 28 includes monogalactosyldiacylglycerol synthase (EC 2.4.1.46) and UDP-N-acetylglucosamine transferase (EC 2.4.1.-). This N-terminal domain contains the acceptor binding site and likely membrane association site. This family also contains a large number of proteins that probably have quite distinct activities. |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| AIH35131.1 | 6.69e-302 | 1 | 414 | 1 | 414 |
| AEM99990.1 | 6.69e-302 | 1 | 414 | 1 | 414 |
| AMC54889.1 | 6.69e-302 | 1 | 414 | 1 | 414 |
| AGM00058.1 | 6.69e-302 | 1 | 414 | 1 | 414 |
| AIH31666.1 | 6.69e-302 | 1 | 414 | 1 | 414 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 3H4I_A | 7.32e-29 | 1 | 401 | 1 | 374 | ChimericGlycosyltransferase for the generation of novel natural products [Amycolatopsis orientalis],3H4T_A Chimeric Glycosyltransferase for the generation of novel natural products - GtfAH1 in complex with UDP-2F-Glc [Amycolatopsis orientalis] |
| 1IIR_A | 5.05e-27 | 1 | 412 | 1 | 400 | CrystalStructure of UDP-glucosyltransferase GtfB [Amycolatopsis orientalis] |
| 1RRV_A | 8.72e-24 | 1 | 401 | 1 | 392 | X-raycrystal structure of TDP-vancosaminyltransferase GtfD as a complex with TDP and the natural substrate, desvancosaminyl vancomycin. [Amycolatopsis orientalis],1RRV_B X-ray crystal structure of TDP-vancosaminyltransferase GtfD as a complex with TDP and the natural substrate, desvancosaminyl vancomycin. [Amycolatopsis orientalis] |
| 1PN3_A | 1.94e-18 | 1 | 388 | 1 | 367 | CrystalStructure of TDP-epi-Vancosaminyltransferase GtfA in complexes with TDP and the acceptor substrate DVV. [Amycolatopsis orientalis],1PN3_B Crystal Structure of TDP-epi-Vancosaminyltransferase GtfA in complexes with TDP and the acceptor substrate DVV. [Amycolatopsis orientalis],1PNV_A Crystal Structure of TDP-epi-Vancosaminyltransferase GtfA in complexes with TDP and Vancomycin [Amycolatopsis orientalis],1PNV_B Crystal Structure of TDP-epi-Vancosaminyltransferase GtfA in complexes with TDP and Vancomycin [Amycolatopsis orientalis] |
| 5XVM_A | 7.33e-13 | 2 | 356 | 21 | 387 | Sterol3-beta-glucosyltransferase (ugt51) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) [Saccharomyces cerevisiae S288C],5XVM_B Sterol 3-beta-glucosyltransferase (ugt51) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) [Saccharomyces cerevisiae S288C] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| P9WN07 | 1.34e-302 | 1 | 414 | 1 | 414 | Uncharacterized glycosyltransferase Rv1524 OS=Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) OX=83332 GN=Rv1524 PE=1 SV=1 |
| P64866 | 1.34e-302 | 1 | 414 | 1 | 414 | Uncharacterized glycosyltransferase Mb1551 OS=Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97) OX=233413 GN=BQ2027_MB1551 PE=3 SV=1 |
| P9WN06 | 1.34e-302 | 1 | 414 | 1 | 414 | Uncharacterized glycosyltransferase MT1575 OS=Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh) OX=83331 GN=MT1575 PE=3 SV=1 |
| Q49929 | 2.65e-176 | 1 | 412 | 1 | 411 | Uncharacterized glycosyltransferase ML2348 OS=Mycobacterium leprae (strain TN) OX=272631 GN=ML2348 PE=3 SV=1 |
| P64870 | 2.52e-163 | 1 | 412 | 1 | 414 | Uncharacterized protein Mb1553c OS=Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97) OX=233413 GN=BQ2027_MB1553C PE=4 SV=1 |
SignalP and Lipop Annotations help
This protein is predicted as OTHER
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 1.000052 | 0.000004 | 0.000000 | 0.000000 | 0.000000 | 0.000000 |