CAZyme Information: MGYG000002335_03234

Basic Information

• Species: Yersinia enterocolitica
• Lineage: Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Yersinia; Yersinia enterocolitica
• CAZyme ID: MGYG000002335_03234
• CAZy Family: GT19
• CAZyme Description: Lipid-A-disaccharide synthase

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
394		43240.55	6.6384

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000002335	4527941	Isolate	not provided	not provided

• Gene Location: Start: 3475130; End: 3476314 Strand: -

Full Sequence      

MQNTPLSVDRPSSSVRPLTIGLVAGETSGDILGAGLIRALKAQVPDARFVGVAGPLMQAE
GCEVWFEMEELAVMGVVEVLERLPRLLKIRKELTQRFSELSPDVFVGIDAPDFNITLEGR
LKQRGIRTVHYVSPSVWAWRQKRVFKIGKATDMVLAFLPFEKAFYDRFNVPCRFIGHTMA
DAMPLAPDKNAAKAELGIAPNTPCLALLPGSRHSEVEMLSGDFLRTAAILQQQLPNLEVL
VPLVNSKRREQFERIKAETAPDLAVHLLDGNARLAMIAADATLLASGTAALECMLAKCPM
VVGYRMKPFTFWLAERLVKTPYVSLPNLLAGEELVTELLQQECQPQKLADALLPLLQGGS
AVEALKERFLILHQSIRCGADEQAAQAVLELAGR

Enzyme Prediction     

No EC number prediction in MGYG000002335_03234.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GT19	20	377	5.4e-139	0.9943502824858758

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
TIGR00215	lpxB	0.0	19	391	7	385	lipid-A-disaccharide synthase. Lipid-A precursor biosynthesis producing lipid A disaccharide in a condensation reaction. transcribed as part of an operon including lpxA [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides]
COG0763	LpxB	0.0	17	394	1	381	Lipid A disaccharide synthetase [Cell wall/membrane/envelope biogenesis].
PRK00025	lpxB	0.0	17	394	1	377	lipid-A-disaccharide synthase; Reviewed
pfam02684	LpxB	1.07e-179	20	388	1	374	Lipid-A-disaccharide synthetase. This is a family of lipid-A-disaccharide synthetases, EC:2.4.2.128. These enzymes catalyze the reaction: UDP-2,3-bis(3-hydroxytetradecanoyl) glucosamine + 2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate <=> UDP + 2,3-bis(3-hydroxytetradecanoyl)-D-glucosaminyl-1,6 -beta-D-2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate. These enzymes catalyze the fist disaccharide step in the synthesis of lipid-A-disaccharide.
PRK01021	lpxB	1.42e-51	22	360	231	574	lipid-A-disaccharide synthase; Reviewed

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
QBP98164.1	5.28e-282	1	394	1	394
ALG79761.1	5.28e-282	1	394	1	394
AOF28262.1	5.28e-282	1	394	1	394
AOF24621.1	5.28e-282	1	394	1	394
CBX69952.1	5.28e-282	1	394	1	394

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
5W8N_A	1.32e-209	16	392	5	381	LipidA Disaccharide Synthase (LpxB)-6 solubilizing mutations [Escherichia coli BL21(DE3)]
5W8S_A	1.08e-208	16	392	5	381	LipidA Disaccharide Synthase (LpxB)-7 solubilizing mutations [Escherichia coli BL21(DE3)],5W8X_A Lipid A Disaccharide Synthase (LpxB)-7 solubilizing mutations-Bound to UDP [Escherichia coli BL21(DE3)]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
Q667K2	4.92e-256	1	394	1	394	Lipid-A-disaccharide synthase OS=Yersinia pseudotuberculosis serotype I (strain IP32953) OX=273123 GN=lpxB PE=3 SV=1
Q8ZH55	4.92e-256	1	394	1	394	Lipid-A-disaccharide synthase OS=Yersinia pestis OX=632 GN=lpxB PE=3 SV=1
Q7N8N4	1.07e-228	14	394	9	389	Lipid-A-disaccharide synthase OS=Photorhabdus laumondii subsp. laumondii (strain DSM 15139 / CIP 105565 / TT01) OX=243265 GN=lpxB PE=3 SV=1
A8GID3	2.74e-227	16	392	4	380	Lipid-A-disaccharide synthase OS=Serratia proteamaculans (strain 568) OX=399741 GN=lpxB PE=3 SV=1
C6DAJ6	1.00e-220	14	391	2	379	Lipid-A-disaccharide synthase OS=Pectobacterium carotovorum subsp. carotovorum (strain PC1) OX=561230 GN=lpxB PE=3 SV=1

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
1.000041	0.000008	0.000000	0.000000	0.000000	0.000000

TMHMM  Annotations     

There is no transmembrane helices in MGYG000002335_03234.