CAZyme Information: MGYG000002042_01535

Basic Information

• Species: CAG-110 sp900762935
• Lineage: Bacteria; Firmicutes_A; Clostridia; Oscillospirales; Oscillospiraceae; CAG-110; CAG-110 sp900762935
• CAZyme ID: MGYG000002042_01535
• CAZy Family: GH39
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
1706		186472.4	4.2718

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000002042	2052895	MAG	China	Asia

• Gene Location: Start: 4462; End: 9582 Strand: -

Full Sequence      

MKLFKRAISALAVLAMVMGLFSSIPVIYAQPNEDGQEQPTTVSATLGQTPVFDGLTLRMK
GDTEWNETPTAGEKDGVGYWMLEPKADDKQNSFYLFGYVDDEVANGGDHYAVLEVTYFDG
EGGHFGATFNTEAQYENWTDTVKLTGTNTWKTHQFVLDGALLNNSLWNKSDFRMGLFVMK
EGLYMSAAPVMISKVTLRLETRPVPRTSVQATLGAAPAFDGLTLKVSGDGAWNENPASGE
LDGVGYWTLSPKSAEDADSFFMYGDVDDDFLYDGSNRIAVKVTYLDSGKGFFSINYNSQT
ASENWGDFVQLEDSGSWKTHTFILPDASLNNHFLGRGMDFRLGLYVTGHGMSKAEVKISK
VEVALAQREMVSAELGPNPVYDGLTVRVRGDGGWNENPTTGELDGVGYLQLKPEADNFYL
FADVDDNYISAGSNCVLVNVTYFDGESGHFSLTYTNPGSNAPVWSDFVRLTGTNTWKTHR
FVMRNAAMSSTLFGWQGDFRVGLYVEGHGMSAAPVNFSKITAQKVDAADFDYVVADLGAD
PVFDGLSMRACGDGAWNNSPKTGELDGRGYWALTPKTDGDKDNFFLFGDVADGYLYGQTD
YVLMDVTYYDGESGHFSLNYRTPEHSEVWGDLVKLEGTKTWKTHTFVLDQAIMTNNHLGK
GDFRLGLFVSGPGMSAGEVLISQVKLWKAERPKTVKTTIETTHSGNIFFGSETIDMALQL
TSDYDGDNTYTVNYWVKDYNGLVLSSGSWQEHLPEPGTNRAELPFLSDITAYGIYSLDIQ
VLTQDGEERCRTEFPFSRVRTGTQLDWLGACTHYGQGKSDPSINLPLMNKGGIRFLRDEI
YWGSVEKEKGVYDFSPYDRFIDEAVANNIEPLLILDYGNALYGGGAPTTDEAITAFTNYC
TALVNRYRGKVKYFEIWNEWNIGLGSVAPEDRGGAAYAKLLVAASKAVREANPDAYILGM
AIANTDPKFIGDVLDYPGAYEAMDAVVLHPYTHPRKPEGGVDNNVAIMTGEFESRNLEPL
PIWITEMGWPTTNDGTTVSEGVAAGYGVRSLMYTMANADKIDKFFWYDFQNDGVDRSYTE
NNFGLIDCWQGPTVPFAAKPGYAAISAFTSVIDGYTYAGQTKLDGAINAFRFTDKTGARQ
DLLVLFTEGTNETVALSAKSGTVLVTDLFGNENRTSGKDVTVSLSDLPVYLTGDFAEDLT
LNKAGFKADSQYTVPAGGVAQITVHRDAEAAKLTGTYELRLPAGWTTTGGTFAAASEATV
DRIPVQVPAGTKTGNYTVSLRAIGDNGEVYCSQILTVTVKELRPYVIAPHLESSKDYTDW
SVAVTVNHFTAGGRKTGTMKLYNMSADPAQLLGELPYDVEPGGSQTLNFRWPAWGPDTYV
VKMVAVDDDGTETVQTRKLSFLAAVERASWQTMTTDGVLDDAEWGDAMEFPLPNYHKLGG
DWNGPEDAAAVGYLKWDAEKLYLAIRLTDDEHFQEATGNNIWQGDSIQFSVDPARSTEPG
LEGNSQTGFALNGTTGTVSNYQWLACIGRAPGALPEETFAVTREGTTTTYEAAIPWEAVT
NDRFEAIENLCVGFSVLVNDNDGGVRKGFLEYMSGIGLGNDVSQFGDLLLAANDSKQPDP
EPTDPEPTDPTPTDPTPTDPTPTDPKPTDPKPTDPAPTDPQPTQPAQPQNPSTGDNRPLV
FFTLLAVFSLAIILTLADELGKRQTR

Enzyme Prediction     

No EC number prediction in MGYG000002042_01535.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH39	846	1111	7.1e-37	0.6682134570765661
CBM9	1416	1608	3.2e-23	0.978021978021978

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
cd09621	CBM9_like_5	6.09e-45	1433	1610	13	188	DOMON-like type 9 carbohydrate binding module. Family 9 carbohydrate-binding modules (CBM9) play a role in the microbial degradation of cellulose and hemicellulose (materials found in plants). The domain has previously been called cellulose-binding domain. The polysaccharide binding sites of CBMs with available 3D structure have been found to be either flat surfaces with interactions formed by predominantly aromatic residues (tryptophan and tyrosine), or extended shallow grooves. CBM9 domains found in this uncharacterized heterogeneous subfamily are often located at the C-terminus of longer proteins and may co-occur with various other functional domains such as glycosyl hydrolases. The CBM9 module in these architectures may be involved in binding to carbohydrates.
cd09619	CBM9_like_4	4.19e-17	1414	1584	3	163	DOMON-like type 9 carbohydrate binding module. Family 9 carbohydrate-binding modules (CBM9) play a role in the microbial degradation of cellulose and hemicellulose (materials found in plants). The domain has previously been called cellulose-binding domain. The polysaccharide binding sites of CBMs with available 3D structure have been found to be either flat surfaces with interactions formed by predominantly aromatic residues (tryptophan and tyrosine), or extended shallow grooves. CBM9 domains found in this uncharacterized heterogeneous subfamily are often located at the C-terminus of longer proteins and may co-occur with various other domains.
pfam06452	CBM9_1	1.21e-11	1416	1610	2	181	Carbohydrate family 9 binding domain-like. CBM9_1 is a C-terminal domain on bacterial xylanase proteins, and it is tandemly repeated in a number of family-members. The CBM9 module binds to amorphous and crystalline cellulose and a range of soluble di- and monosaccharides as well as to cello- and xylo- oligomers of different degrees of polymerization. Comparison of the glucose and cellobiose complexes during crystallisation reveals surprising differences in binding of these two substrates by CBM9-2. Cellobiose was found to bind in a distinct orientation from glucose, while still maintaining optimal stacking and electrostatic interactions with the reducing end sugar.
pfam00232	Glyco_hydro_1	2.92e-10	810	980	53	226	Glycosyl hydrolase family 1.
cd00241	DOMON_like	3.90e-10	1438	1592	8	158	Domon-like ligand-binding domains. DOMON-like domains can be found in all three kindgoms of life and are a diverse group of ligand binding domains that have been shown to interact with sugars and hemes. DOMON domains were initially thought to confer protein-protein interactions. They were subsequently found as a heme-binding motif in cellobiose dehydrogenase, an extracellular fungal oxidoreductase that degrades both lignin and cellulose, and in ethylbenzene dehydrogenase, an enzyme that aids in the anaerobic degradation of hydrocarbons. The domain interacts with sugars in the type 9 carbohydrate binding modules (CBM9), which are present in a variety of glycosyl hydrolases, and it can also be found at the N-terminus of sensor histidine kinases.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
QHT61380.1	1.01e-124	265	1623	85	1311
AIQ58724.1	7.04e-122	221	1610	32	1279
QHW29837.1	8.18e-122	209	1623	41	1315
AIQ29998.1	9.51e-120	203	1610	28	1285
QJU55032.1	2.25e-98	705	1620	220	1096

PDB Hits     

has no PDB hit.

Swiss-Prot Hits     

has no Swissprot hit.

SignalP and Lipop Annotations

This protein is predicted as SP

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
0.000286	0.998983	0.000204	0.000204	0.000171	0.000146

TMHMM  Annotations     

start	end
7	29
1678	1697