logo
sublogo
You are browsing environment: HUMAN GUT
help

CAZyme Information: MGYG000001985_00040

You are here: Home > Sequence: MGYG000001985_00040

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species CAG-495 sp900540425
Lineage Bacteria; Proteobacteria; Alphaproteobacteria; RF32; CAG-239; CAG-495; CAG-495 sp900540425
CAZyme ID MGYG000001985_00040
CAZy Family GH23
CAZyme Description Membrane-bound lytic murein transglycosylase C
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
593 MGYG000001985_1|CGC1 68819.09 10.2069
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000001985 1740183 MAG Spain Europe
Gene Location Start: 41364;  End: 43145  Strand: -

Full Sequence      Download help

Enzyme Prediction      help

No EC number prediction in MGYG000001985_00040.

CAZyme Signature Domains help

Family Start End Evalue family coverage
GH23 436 567 6.9e-24 0.8074074074074075

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
cd13401 Slt70-like 1.27e-52 423 571 2 152
70kDa soluble lytic transglycosylase (Slt70) and similar proteins. Catalytic domain of the 70kda soluble lytic transglycosylase (LT)-like proteins, which also have an N-terminal U-shaped U-domain and a linker L-domain. LTs catalyze the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid (MurNAc) and N-acetyl-D-glucosamine (GlcNAc), as do "goose-type" lysozymes. However, in addition to this, they also make a new glycosidic bond with the C6 hydroxyl group of the same muramic acid residue. Proteins similar to this family include the soluble and insoluble membrane-bound LTs in bacteria and the LTs in bacteriophage lambda.
cd16896 LT_Slt70-like 2.81e-38 435 565 16 144
uncharacterized lytic transglycosylase subfamily with similarity to Slt70. Uncharacterized lytic transglycosylase (LT) with a conserved sequence pattern suggesting similarity to the Slt70, a 70kda soluble lytic transglycosylase which also has an N-terminal U-shaped U-domain and a linker L-domain. LTs catalyze the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid (MurNAc) and N-acetyl-D-glucosamine (GlcNAc), as do "goose-type" lysozymes. However, in addition to this, they also make a new glycosidic bond with the C6 hydroxyl group of the same muramic acid residue.
cd00254 LT-like 2.10e-34 438 566 1 111
lytic transglycosylase(LT)-like domain. Members include the soluble and insoluble membrane-bound LTs in bacteria and LTs in bacteriophage lambda. LTs catalyze the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid (MurNAc) and N-acetyl-D-glucosamine (GlcNAc), as do "goose-type" lysozymes. However, in addition to this, they also make a new glycosidic bond with the C6 hydroxyl group of the same muramic acid residue.
COG0741 MltE 2.98e-31 303 580 16 295
Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell wall/membrane/envelope biogenesis].
PRK11619 PRK11619 3.87e-25 267 587 336 640
lytic murein transglycosylase; Provisional

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
QIM10634.1 2.18e-122 41 588 29 575
QDE26880.1 8.64e-100 54 589 55 613
AEP10287.1 6.21e-98 58 583 217 748
AGH98689.1 1.02e-97 58 583 209 740
AUG55166.1 1.04e-97 38 589 49 602

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
5MPQ_A 9.86e-21 285 579 276 566
BulgecinA: The key to a broad-spectrum inhibitor that targets lytic transglycosylases [Neisseria meningitidis]
5O1J_A 9.99e-21 285 579 280 570
Lytictransglycosylase in action [Neisseria meningitidis MC58]
6FPN_B 1.02e-20 285 579 286 576
Lytictransglycosylase in action [Neisseria meningitidis MC58]
5O24_A 1.03e-20 285 579 290 580
Lytictransglycosylase in action [Neisseria meningitidis]
5O29_A 1.05e-20 285 579 296 586
Lytictransglycosylase in action [Neisseria meningitidis]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
P39434 2.67e-19 182 587 251 641
Soluble lytic murein transglycosylase OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) OX=99287 GN=slt PE=3 SV=2
P0AGC3 8.23e-19 312 587 376 641
Soluble lytic murein transglycosylase OS=Escherichia coli (strain K12) OX=83333 GN=slt PE=1 SV=1
P0AGC4 8.23e-19 312 587 376 641
Soluble lytic murein transglycosylase OS=Escherichia coli O157:H7 OX=83334 GN=slt PE=3 SV=1
P44888 5.59e-14 312 574 323 578
Putative soluble lytic murein transglycosylase OS=Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) OX=71421 GN=slt PE=3 SV=1
O31608 1.79e-13 436 566 73 180
Putative murein lytic transglycosylase YjbJ OS=Bacillus subtilis (strain 168) OX=224308 GN=yjbJ PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as SP

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
0.004035 0.560491 0.434426 0.000534 0.000278 0.000208

TMHMM  Annotations      download full data without filtering help

start end
21 40