dbCAN-seq: a database of CAZyme sequence and annotation

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CAZyme Information: MGYG000001576_01011

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Basic Information help

Species

Dysosmobacter sp014297375

Lineage

Bacteria; Firmicutes_A; Clostridia; Oscillospirales; Oscillospiraceae; Dysosmobacter; Dysosmobacter sp014297375

CAZyme ID

MGYG000001576_01011

CAZy Family

CBM50

CAZyme Description

hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
447	MGYG000001576_6\|CGC1	46041.82	4.4036

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000001576	3081635	MAG	United States	North America

Gene Location

Start: 94602; End: 95945 Strand: +

Full Sequence Download help

Enzyme Prediction help

No EC number prediction in MGYG000001576_01011.

CAZyme Signature Domains help

Family	Start	End	Evalue	family coverage
CBM50	403	446	1.8e-16	0.975

CDD Domains download full data without filtering help

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
cd02252	nylC_like	2.80e-92	38	347	3	259	nylC-like family; composed of proteins with similarity to Flavobacterium endo-type 6-aminohexanoate-oligomer hydrolase (EIII), the product of the nylon oligomer degradation gene, nylC. EIII is an amide hydrolase that catalyzes the degradation of highly-polymerized 6-aminohexanoate oligomers. Together with other nylon degradation enzymes, such as 6-aminohexanoate cyclic dimer hydrolase (EI) and 6-aminohexanoate dimer hydrolase (EII), EIII plays a role in the detoxification and biological removal of the synthetic by-products of nylon manufacture. EIII shows sequence similarity to L-aminopeptidase D-amidase/D-esterase (DmpA), an aminopeptidase that releases N-terminal D and L amino acids from peptide substrates. Like DmpA, EIII undergoes autocatalytic cleavage in front of a nucleophile to form a heterodimer. DmpA shows similarity in catalytic mechanism to N-terminal nucleophile (Ntn) hydrolases, which are enzymes that catalyze the cleavage of amide bonds through the nucleophilic attack of the side chain of an N-terminal serine, threonine, or cysteine.
COG3191	DmpA	7.00e-68	38	363	19	339	L-aminopeptidase/D-esterase [Amino acid transport and metabolism, Secondary metabolites biosynthesis, transport and catabolism].
pfam03576	Peptidase_S58	4.57e-46	38	356	5	309	Peptidase family S58.
cd00118	LysM	3.42e-16	401	445	1	45	Lysin Motif is a small domain involved in binding peptidoglycan. LysM, a small globular domain with approximately 40 amino acids, is a widespread protein module involved in binding peptidoglycan in bacteria and chitin in eukaryotes. The domain was originally identified in enzymes that degrade bacterial cell walls, but proteins involved in many other biological functions also contain this domain. It has been reported that the LysM domain functions as a signal for specific plant-bacteria recognition in bacterial pathogenesis. Many of these enzymes are modular and are composed of catalytic units linked to one or several repeats of LysM domains. LysM domains are found in bacteria and eukaryotes.
pfam01476	LysM	1.76e-15	403	446	1	43	LysM domain. The LysM (lysin motif) domain is about 40 residues long. It is found in a variety of enzymes involved in bacterial cell wall degradation. This domain may have a general peptidoglycan binding function. The structure of this domain is known.

CAZyme Hits help

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
BCK83709.1	3.07e-301	1	447	1	447
QHZ47012.1	2.77e-10	399	445	214	260
CDM70433.1	6.98e-10	374	446	194	266
ASB88452.1	8.99e-10	385	445	203	261
QFG73306.1	1.27e-09	388	445	408	464

PDB Hits download full data without filtering help

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
3TM1_A	4.69e-54	38	369	57	405	Crystalstructure of mature ThnT, a pantetheine hydrolase [Streptomyces cattleya],3TM1_B Crystal structure of mature ThnT, a pantetheine hydrolase [Streptomyces cattleya],3TM2_A Crystal structure of mature ThnT with a covalently bound product mimic [Streptomyces cattleya],3TM2_B Crystal structure of mature ThnT with a covalently bound product mimic [Streptomyces cattleya]
4IHE_A	2.50e-53	38	369	57	405	CrystalStructure of Uncleaved ThnT T282A [Streptomyces cattleya],4IHE_B Crystal Structure of Uncleaved ThnT T282A [Streptomyces cattleya]
3S3U_A	3.50e-53	38	369	57	405	CrystalStructure of Uncleaved ThnT T282C [Streptomyces cattleya],3S3U_B Crystal Structure of Uncleaved ThnT T282C [Streptomyces cattleya],4IHD_A Crystal Structure of Uncleaved ThnT T282C, derivatized at the active site with EtHg [Streptomyces cattleya],4IHD_B Crystal Structure of Uncleaved ThnT T282C, derivatized at the active site with EtHg [Streptomyces cattleya]

Swiss-Prot Hits download full data without filtering help

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
P64812	5.01e-50	38	358	6	332	Uncharacterized aminopeptidase Mb1368 OS=Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97) OX=233413 GN=BQ2027_MB1368 PE=3 SV=1
P9WM22	5.01e-50	38	358	6	332	Uncharacterized aminopeptidase MT1375 OS=Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh) OX=83331 GN=MT1375 PE=3 SV=1
P9WM23	5.01e-50	38	358	6	332	Uncharacterized aminopeptidase Rv1333 OS=Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) OX=83332 GN=Rv1333 PE=1 SV=1
P53425	2.15e-49	38	362	13	347	Uncharacterized aminopeptidase ML1167 OS=Mycobacterium leprae (strain TN) OX=272631 GN=ML1167 PE=3 SV=1
Q5HRU2	6.19e-07	396	444	79	126	N-acetylmuramoyl-L-alanine amidase sle1 OS=Staphylococcus epidermidis (strain ATCC 35984 / RP62A) OX=176279 GN=sle1 PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as SP

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
0.000202	0.999190	0.000165	0.000160	0.000145	0.000134

TMHMM Annotations download full data without filtering help

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