CAZyme Information: MGYG000001514_00747

Basic Information

• Species: Paenibacillus_A ihumii
• Lineage: Bacteria; Firmicutes; Bacilli; Paenibacillales; Paenibacillaceae; Paenibacillus_A; Paenibacillus_A ihumii
• CAZyme ID: MGYG000001514_00747
• CAZy Family: GH115
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
1262		139094.26	5.0524

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000001514	5923787	Isolate	not provided	not provided

• Gene Location: Start: 195415; End: 199203 Strand: +

Full Sequence      

MFSENYVVGQASGDGAFRLVHEGSSADIYISAEDHAGVVRAAKDLQADIGRVSGQSPMLM
HDPKLLASHAVLIGTIGKSPIIDALIAEGKLDAGDVTGKWESFVIQTVAHPLPGVEQGLV
IAGSDKRGTIFGIYDVSEKIGVSPWYWWADVPAVRKNSLFIVPGTYKQGEPSVKYRGIFL
NDEGPSLMAWVRANYRDFTHEFYEKIFELLLRLKANYLWPAMWDNTFYEDDPLNAEVADR
YGIVIGTSHHEPMLRPHGDWKKHKEGPWDYSVNEDVLYRFWEEGIRRSRDYESIVTLGMR
GDGDEAMGGHLSLEEKIVLLEKIVSDQRKIIAEQTGRAPSEVPQLWALYKEVQDYYEHGM
RVPDDITLLWSDDNHGNLRRVPASEERQRSGGAGIYYHLDYVGGPRSYKWINTVPVPKIW
EQMHKAYEYGADRIWIVNVGDLKPMEFPLEYFLRMAWDISQFTKDNAWECTVRWAQQQFG
PKYGEEAAEILTGYAKFNGRIKPELLNGVELYSLTDYKEAELASAELKSISSKAEQLYNE
LPEQLRDAFFQLALYPAQASAQVLELHLQAARSRLYARQGRAAANIAAREAELLFEADRE
LTLAYNKMLSQGKWDHLMDQTHIGYTYWNQPPVNAMPETGTVAAKEYFEMGIAVEGSADV
WPDVNTVCRLPEFNSFTREARYIDVFNKGTEPFTFRAAAGAPWIKLSISSGEIVTQQRIW
VDIDWAAAPVGHEVHGEIVISGPTGEEVAVQILVFHPAEPTRESLVGHIETGGVIAIEAE
HFSASHSASGAKWQPIAGYGRTLSSVAVFPVTAPSAEQPHPENSPSLEYPVYLTSTGEIS
VTLYAAPSIDFVVGQGLRIGVSFDDGPVQIAGLIAKMPDGGFDEGDGEQSVIYNIRTGAT
RHLIEQPGYHTLRIWMVDPIVVLQKLVIDTGGQKPSLLGPPESYYNGLPAGTEPWALQTA
DRESFDPFVVPGILGGCCTSPEEKLDIFVQQSGLYTLKLAAIVKPGDKPMLRLRIDGLEL
PGPICLRPAENRSGSLRYIAENIPLQAGRHSLQFTAEHCRALNGEMQLQLAAPDRLRVRP
LLQRSGLLPEKPLVAQIGLLGIDERCSCRYAVTVSLYSEDDRLLDEAAVTGIVPRGGEEV
QRVCLADPRLGSEVRGYALAADSCKAGGHALAAGSGRAASLAQTAGDGKALSGSGGTEAS
MAQCSAAKSGATESGMTPSSNAEWSRTQNGEKWAGGSATRYKLKLAITYDGITRMHCSNW
IL

Enzyme Prediction     

EC	3.2.1.131

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH115	15	646	1.2e-263	0.8579626972740315

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
pfam15979	Glyco_hydro_115	0.0	169	505	1	334	Glycosyl hydrolase family 115. Glyco_hydro_115 is a family of glycoside hydrolases likely to have the activity of xylan a-1,2-glucuronidase, EC:3.2.1.131, or a-(4-O-methyl)-glucuronidase EC:3.2.1.-.
pfam17829	GH115_C	1.97e-66	767	942	1	172	Gylcosyl hydrolase family 115 C-terminal domain. This domain is found at the C-terminus of glycosyl hydrolase family 115 proteins. This domain has a beta-sandwich fold.
pfam03648	Glyco_hydro_67N	4.75e-04	30	135	24	119	Glycosyl hydrolase family 67 N-terminus. Alpha-glucuronidases, components of an ensemble of enzymes central to the recycling of photosynthetic biomass, remove the alpha-1,2 linked 4-O-methyl glucuronic acid from xylans. This family represents the N-terminal region of alpha-glucuronidase. The N-terminal domain forms a two-layer sandwich, each layer being formed by a beta sheet of five strands. A further two helices form part of the interface with the central, catalytic, module (pfam07488).

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
AOZ93060.1	0.0	17	1145	16	1161
AZP03538.1	0.0	1	1147	1	1090
ARS36448.1	0.0	8	943	51	974
AKD05468.1	0.0	14	944	43	961
AKQ47511.1	0.0	14	945	32	951

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
4ZMH_A	9.98e-297	14	947	11	937	Crystalstructure of a five-domain GH115 alpha-Glucuronidase from the Marine Bacterium Saccharophagus degradans 2-40T [Saccharophagus degradans 2-40],4ZMH_B Crystal structure of a five-domain GH115 alpha-Glucuronidase from the Marine Bacterium Saccharophagus degradans 2-40T [Saccharophagus degradans 2-40]
7PUG_A	7.83e-198	17	943	17	834	ChainA, xylan alpha-1,2-glucuronidase [uncultured bacterium]
4C90_A	3.36e-197	3	943	31	849	Evidencethat GH115 alpha-glucuronidase activity is dependent on conformational flexibility [Bacteroides ovatus],4C90_B Evidence that GH115 alpha-glucuronidase activity is dependent on conformational flexibility [Bacteroides ovatus],4C91_A Evidence that GH115 alpha-glucuronidase activity is dependent on conformational flexibility [Bacteroides ovatus],4C91_B Evidence that GH115 alpha-glucuronidase activity is dependent on conformational flexibility [Bacteroides ovatus]
7PXQ_A	3.23e-196	17	943	16	833	ChainA, xylan alpha-1,2-glucuronidase [uncultured bacterium]
6NPS_A	4.44e-173	24	947	18	967	Crystalstructure of GH115 enzyme AxyAgu115A from Amphibacillus xylanus [Amphibacillus xylanus NBRC 15112],6NPS_B Crystal structure of GH115 enzyme AxyAgu115A from Amphibacillus xylanus [Amphibacillus xylanus NBRC 15112]

Swiss-Prot Hits     

has no Swissprot hit.

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
1.000056	0.000000	0.000000	0.000000	0.000000	0.000000

TMHMM  Annotations     

There is no transmembrane helices in MGYG000001514_00747.