CAZyme Information: MGYG000001503_02256

Basic Information

• Species: Fermentimonas caenicola
• Lineage: Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Dysgonomonadaceae; Fermentimonas; Fermentimonas caenicola
• CAZyme ID: MGYG000001503_02256
• CAZy Family: GT19
• CAZyme Description: Lipid-A-disaccharide synthase

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
377		42830.56	8.8021

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000001503	2824716	Isolate	not provided	not provided

• Gene Location: Start: 1511122; End: 1512255 Strand: +

Full Sequence      

MKYYIVAGEASGDLHASNLMKSLKQLDKEAEFRFFGGDLMKSAGGTLVKHYREMAFMGII
PVIMNSRTILKNLSICKKDIANYNPDAVILVDYPGFNLKIAKYVKTELKIPVFYYISPKV
WAWKEYRVKSFKKYVDEMLCILPFEVEFFKKHNYDVHYVGNPTVDAIAGRDHKDETFSDF
IKSNNLPDKPIIALLAGSRKQEIAGNLPLMLKSVESYADGYQFIIAGAPGIDREFYKNYT
LSNPDIVVLFDQTYRILAQSDAALVTSGTATLETAILNVPQVVCYSMPSPRLSSWAFRNI
LHTPYISLVNLICGQEVVKEYFAATFTVENVRKELGQMLHVQKYRQNMLNNYKEMRDILG
ESGASDRAAQIIYSKTN

Enzyme Prediction     

No EC number prediction in MGYG000001503_02256.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GT19	4	359	8.8e-116	0.9887005649717514

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
PRK00025	lpxB	2.81e-114	1	372	2	371	lipid-A-disaccharide synthase; Reviewed
COG0763	LpxB	2.04e-103	1	372	2	375	Lipid A disaccharide synthetase [Cell wall/membrane/envelope biogenesis].
pfam02684	LpxB	7.89e-80	4	346	2	357	Lipid-A-disaccharide synthetase. This is a family of lipid-A-disaccharide synthetases, EC:2.4.2.128. These enzymes catalyze the reaction: UDP-2,3-bis(3-hydroxytetradecanoyl) glucosamine + 2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate <=> UDP + 2,3-bis(3-hydroxytetradecanoyl)-D-glucosaminyl-1,6 -beta-D-2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate. These enzymes catalyze the fist disaccharide step in the synthesis of lipid-A-disaccharide.
TIGR00215	lpxB	6.95e-66	5	370	10	380	lipid-A-disaccharide synthase. Lipid-A precursor biosynthesis producing lipid A disaccharide in a condensation reaction. transcribed as part of an operon including lpxA [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides]
PRK14089	PRK14089	2.40e-46	1	373	2	345	lipid-A-disaccharide synthase.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
CEA16829.1	1.23e-276	1	377	1	377
SCD19091.1	1.51e-214	1	375	1	375
SCM56036.1	1.71e-205	1	375	1	373
QRX64804.1	2.06e-204	1	375	1	375
BBD46706.1	1.07e-203	1	375	1	373

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
5W8S_A	2.49e-37	5	372	11	377	LipidA Disaccharide Synthase (LpxB)-7 solubilizing mutations [Escherichia coli BL21(DE3)],5W8X_A Lipid A Disaccharide Synthase (LpxB)-7 solubilizing mutations-Bound to UDP [Escherichia coli BL21(DE3)]
5W8N_A	6.69e-37	5	372	11	377	LipidA Disaccharide Synthase (LpxB)-6 solubilizing mutations [Escherichia coli BL21(DE3)]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
Q1D393	1.14e-67	5	372	9	374	Lipid-A-disaccharide synthase OS=Myxococcus xanthus (strain DK1622) OX=246197 GN=lpxB PE=3 SV=1
Q39T49	4.62e-67	5	372	11	376	Lipid-A-disaccharide synthase OS=Geobacter metallireducens (strain ATCC 53774 / DSM 7210 / GS-15) OX=269799 GN=lpxB PE=3 SV=1
Q2LVL8	6.97e-66	5	369	8	371	Lipid-A-disaccharide synthase OS=Syntrophus aciditrophicus (strain SB) OX=56780 GN=lpxB PE=3 SV=1
Q6ALW0	1.65e-64	5	374	14	384	Lipid-A-disaccharide synthase OS=Desulfotalea psychrophila (strain LSv54 / DSM 12343) OX=177439 GN=lpxB PE=3 SV=1
B6J161	7.62e-63	5	374	8	372	Lipid-A-disaccharide synthase OS=Coxiella burnetii (strain CbuG_Q212) OX=434923 GN=lpxB PE=3 SV=1

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
1.000041	0.000001	0.000000	0.000000	0.000000	0.000000

TMHMM  Annotations     

There is no transmembrane helices in MGYG000001503_02256.