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CAZyme Information: MGYG000001420_02566
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | Alistipes senegalensis | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Rikenellaceae; Alistipes; Alistipes senegalensis | |||||||||||
| CAZyme ID | MGYG000001420_02566 | |||||||||||
| CAZy Family | GH33 | |||||||||||
| CAZyme Description | Sialidase | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 972840; End: 974015 Strand: + | |||||||||||
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| GH33 | 39 | 382 | 8.1e-89 | 0.9649122807017544 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| cd15482 | Sialidase_non-viral | 5.02e-105 | 38 | 382 | 3 | 338 | Non-viral sialidases. Sialidases or neuraminidases function to bind and hydrolyze terminal sialic acid residues from various glycoconjugates, they play vital roles in pathogenesis, bacterial nutrition and cellular interactions. They have a six-bladed, beta-propeller fold with the non-viral sialidases containing 2-5 Asp-box motifs (most commonly Ser/Thr-X-Asp-[X]-Gly-X-Thr- Trp/Phe). This CD includes eubacterial and eukaryotic sialidases. |
| pfam13088 | BNR_2 | 1.56e-36 | 60 | 365 | 1 | 280 | BNR repeat-like domain. This family of proteins contains BNR-like repeats suggesting these proteins may act as sialidases. |
| pfam13859 | BNR_3 | 1.53e-11 | 60 | 255 | 9 | 193 | BNR repeat-like domain. This family of proteins contains BNR-like repeats suggesting these proteins may act as sialidases. |
| COG4409 | NanH | 5.94e-11 | 65 | 375 | 383 | 707 | Neuraminidase (sialidase) [Carbohydrate transport and metabolism, Cell wall/membrane/envelope biogenesis]. |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| QIU96716.1 | 4.44e-105 | 35 | 387 | 34 | 368 |
| QRP58590.1 | 6.28e-105 | 35 | 387 | 34 | 368 |
| QQT79528.1 | 6.28e-105 | 35 | 387 | 34 | 368 |
| QNL38454.1 | 6.28e-105 | 1 | 387 | 13 | 368 |
| ASM67226.1 | 6.28e-105 | 35 | 387 | 34 | 368 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 5TSP_A | 1.32e-31 | 38 | 368 | 13 | 430 | Crystalstructure of the catalytic domain of Clostridium perfringens neuraminidase (NanI) in complex with a CHES [Clostridium perfringens ATCC 13124],5TSP_B Crystal structure of the catalytic domain of Clostridium perfringens neuraminidase (NanI) in complex with a CHES [Clostridium perfringens ATCC 13124] |
| 2BF6_A | 1.56e-31 | 38 | 368 | 12 | 429 | AtomicResolution Structure of the bacterial sialidase NanI from Clostridium perfringens in complex with alpha-Sialic Acid (Neu5Ac). [Clostridium perfringens] |
| 2VK5_A | 1.62e-31 | 38 | 368 | 12 | 429 | TheStructure Of Clostridium Perfringens Nani Sialidase And Its Catalytic Intermediates [Clostridium perfringens],2VK6_A The Structure Of Clostridium Perfringens Nani Sialidase And Its Catalytic Intermediates [Clostridium perfringens],2VK7_A The Structure Of Clostridium Perfringens Nani Sialidase And Its Catalytic Intermediates [Clostridium perfringens],2VK7_B The Structure Of Clostridium Perfringens Nani Sialidase And Its Catalytic Intermediates [Clostridium perfringens] |
| 7P1B_C | 8.08e-30 | 49 | 388 | 62 | 405 | ChainC, Sialidase domain-containing protein [Aspergillus terreus NIH2624],7P1D_A Chain A, Sialidase domain-containing protein [Aspergillus terreus NIH2624],7P1E_A Chain A, Sialidase domain-containing protein [Aspergillus terreus NIH2624],7P1F_A Chain A, Sialidase domain-containing protein [Aspergillus terreus NIH2624],7P1F_B Chain B, Sialidase domain-containing protein [Aspergillus terreus NIH2624],7P1O_A Chain A, Sialidase domain-containing protein [Aspergillus terreus NIH2624],7P1O_X Chain X, Sialidase domain-containing protein [Aspergillus terreus NIH2624] |
| 6MNJ_A | 1.48e-28 | 42 | 368 | 193 | 521 | Hadzamicrobial sialidase Hz136 [Alistipes],6MNJ_B Hadza microbial sialidase Hz136 [Alistipes] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| O35657 | 2.30e-29 | 49 | 372 | 71 | 392 | Sialidase-1 OS=Mus musculus OX=10090 GN=Neu1 PE=1 SV=1 |
| P31206 | 4.26e-28 | 42 | 368 | 196 | 526 | Sialidase OS=Bacteroides fragilis (strain YCH46) OX=295405 GN=nanH PE=3 SV=2 |
| Q99PW3 | 1.05e-27 | 49 | 372 | 71 | 392 | Sialidase-1 OS=Rattus norvegicus OX=10116 GN=Neu1 PE=1 SV=1 |
| Q4WQS0 | 1.90e-27 | 49 | 388 | 58 | 401 | Exo-alpha-sialidase OS=Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) OX=330879 GN=AFUA_4G13800 PE=1 SV=2 |
| A6BMK7 | 2.14e-27 | 49 | 372 | 77 | 398 | Sialidase-1 OS=Bos taurus OX=9913 GN=NEU1 PE=2 SV=2 |
SignalP and Lipop Annotations help
This protein is predicted as LIPO
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 0.000004 | 0.000001 | 1.000028 | 0.000000 | 0.000000 | 0.000000 |