CAZyme Information: MGYG000001289_01663

Basic Information

• Species: Streptococcus sp900543065
• Lineage: Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae; Streptococcus; Streptococcus sp900543065
• CAZyme ID: MGYG000001289_01663
• CAZy Family: GH29
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
1469		162085.82	5.0212

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000001289	1985520	MAG	Italy	Europe

• Gene Location: Start: 7275; End: 11684 Strand: -

Full Sequence      

MNRYFFEKGLTFSIRKLSVGVASVIVGLSFFASGVAHADDQASETPANLENTVSADKPTL
DSAAKPDRAALLHQTPSVTEREVPTSSEDKISENTSEKATPETTTRNSEMTDMKLDTANS
NKPLPSANTSESPSEINHANPVTPVTPSVHTQDDEAEIGNYGPLPSKAQLDYHKEELAAF
IHYGMNTYTNSEWGNGKEDPKNFNPTNLDTDQWVKTLKDAGFKRTILVVKHHDGFVLYPS
RYTDHTVASSSWKDGKGDVLAEISKSATKYDMNLGVYLSPWDVNNPKYTVATEKDYNEYY
LNQLKEILGNPKYGNKGKFIEVWMDGARGSGAQKVTYTFDKWFQYIKEAEGDIAIFSAQP
TSIRWIGNERGTAGDPVWQKVKKANITDNVTNDYLNHGDPDGDMYSVGEADVSIRSGWFY
HDNQQPKSLKELMEIYFKSVGRGTPLLLNIPPNKEGKFAEADVARLKEFRATLDQMYATD
FAKGETVTASSTRKNHLYQASYLTDGNENTSWAPANDAKTGEFTVDLGQKRRFDVIELKE
DIAKGQRISGFKIDVELNGRWVPYGEGSTVGYRRLIQGQPVEAQKIRVRITDAQATPILN
NFSVYKVPSSIEKTDGFPLGLEYHSNTSADTAGTTWYNEAEGVRGTSMWTNQQNASATYH
FQGSKAYVVATVDPHHGEMSVYVDGQKVADVQTKNASRKRSQLVYETGDLAPGEHTLKLV
NKTGEPIATEGIYTLNNAGKGMFELKETSYDVQKGQPVTVTIKRVGGHNGTATVHVVTEP
GTGVHGKVYKDTTADLTFADGETEKTMTVPTIDFTEQADSIFDFKVKMTSASDNALLGFA
SEATVRVMKADLLKQHENNYDDQAKQLEYSPGWHHETNSAGKYQNTESWASFGRMTDEQK
KNTSVTAYFYGTGLEIKGFVDPGHGIYKVSLDGKVLDYQDGQGNASVLDGKKYFSGKASS
RQGDQTIVRLMDLEEGWHALRLQLDPERNDLGQNIGIQVDQFITHGENSALYTKEEVIQA
MQEWKTDLDSFDQSDLKDTPVARQAFKTNLETFSRQLTTSPVDVEKLLLTVASLQEILAN
DDNFAKVEEIPNLKNPEETTQPNKPTDSKIVYDKTIQALTEAFDQKAKELTGDKVALKKL
VDLTEHALASIQEAKTQEVLDKALQDVLTAIHQLQATPKAEPSEPVQPEKPAEPVKPVQP
EKPAEPVKPVQPEKPVEPSEPAQPAKPAQPVKPVEPSKPAQPVEPAEPVKPVQPEKPVEP
SEPAKPVKPAEPSEPAKPVEPVEKVFATSIPSEGVKDLVYHLPSLEIVHHALPFKTIRRD
TTQLEKGNEQILTQGKAGDQVEYIQVNGNERTSLLVETTPPVDEIIEVGTKEIPQHSFGT
ELPPIIARPEYPLPTETSALSNPVGTRVDTKSGDATLSPIKDSNTSSVKTTKAEKQLPNT
GEETATALLWLATITAILSLLVFHRNLKD

Enzyme Prediction     

No EC number prediction in MGYG000001289_01663.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH29	167	473	5.4e-70	0.8583815028901735

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
COG3669	AfuC	9.82e-104	162	605	8	430	Alpha-L-fucosidase [Carbohydrate transport and metabolism].
smart00812	Alpha_L_fucos	1.18e-29	180	498	31	367	Alpha-L-fucosidase. O-Glycosyl hydrolases (EC 3.2.1.-) are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A classification system for glycosyl hydrolases, based on sequence similarity, has led to the definition of 85 different families. This classification is available on the CAZy (CArbohydrate-Active EnZymes) web site. Because the fold of proteins is better conserved than their sequences, some of the families can be grouped in 'clans'. Family 29 encompasses alpha-L-fucosidases, which is a lysosomal enzyme responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins. Deficiency of alpha-L-fucosidase results in the lysosomal storage disease fucosidosis.
pfam01120	Alpha_L_fucos	5.73e-29	203	468	79	323	Alpha-L-fucosidase.
PTZ00449	PTZ00449	8.86e-16	1178	1278	569	669	104 kDa microneme/rhoptry antigen; Provisional
NF033804	Streccoc_I_II	1.58e-15	1177	1309	833	988	antigen I/II family LPXTG-anchored adhesin. Members of the antigen I/II family are adhesins with a glucan-binding domain, two types of repetitive regions, an isopeptide bond-forming domain associated with shear resistance, and a C-terminal LPXTG motif for anchoring to the cell wall. They occur in oral Streptococci, and tend to be major cell surface adhesins. Members of this family include SspA and SspB from Streptococcus gordonii, antigen I/II from S. mutans, etc.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
QUB39236.1	0.0	1	1469	1	1505
QRO08274.1	0.0	139	1469	626	1959
QQL00493.1	0.0	139	1469	626	1959
BAV79264.1	0.0	139	1469	626	1995
ATF56062.1	0.0	139	1469	626	1986

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
6ORG_A	1.02e-181	157	608	3	451	Crystalstructure of SpGH29 [Streptococcus pneumoniae TIGR4],6ORG_B Crystal structure of SpGH29 [Streptococcus pneumoniae TIGR4]
6OR4_A	1.48e-180	157	608	3	451	Crystalstructure of SpGH29 [Streptococcus pneumoniae TIGR4],6OR4_B Crystal structure of SpGH29 [Streptococcus pneumoniae TIGR4],6ORH_A Crystal structure of SpGH29 [Streptococcus pneumoniae TIGR4],6ORH_B Crystal structure of SpGH29 [Streptococcus pneumoniae TIGR4]
6ORF_A	1.53e-180	157	608	3	451	Crystalstructure of SpGH29 [Streptococcus pneumoniae TIGR4],6ORF_B Crystal structure of SpGH29 [Streptococcus pneumoniae TIGR4]
6TR3_A	1.38e-115	164	632	27	530	Ruminococcusgnavus GH29 fucosidase E1_10125 in complex with fucose [[Ruminococcus] gnavus E1]
6TR4_A	1.83e-114	164	632	27	530	Ruminococcusgnavus GH29 fucosidase E1_10125 D221A mutant in complex with fucose [[Ruminococcus] gnavus E1],6TR4_B Ruminococcus gnavus GH29 fucosidase E1_10125 D221A mutant in complex with fucose [[Ruminococcus] gnavus E1]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
Q7XUR3	2.64e-108	163	628	38	493	Putative alpha-L-fucosidase 1 OS=Oryza sativa subsp. japonica OX=39947 GN=Os04g0560400 PE=3 SV=2
Q8GW72	2.31e-101	163	605	36	477	Alpha-L-fucosidase 1 OS=Arabidopsis thaliana OX=3702 GN=FUC1 PE=1 SV=2
P49713	9.31e-07	201	506	90	375	Putative alpha-L-fucosidase OS=Caenorhabditis elegans OX=6239 GN=W03G11.3 PE=3 SV=2

SignalP and Lipop Annotations

This protein is predicted as SP

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
0.000552	0.998583	0.000305	0.000191	0.000177	0.000150

TMHMM  Annotations     

start	end
1444	1463