You are browsing environment: HUMAN GUT
CAZyme Information: MGYG000001117_00783
You are here: Home > Sequence: MGYG000001117_00783
Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | Phascolarctobacterium_A sp900547415 | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Firmicutes_C; Negativicutes; Acidaminococcales; Acidaminococcaceae; Phascolarctobacterium_A; Phascolarctobacterium_A sp900547415 | |||||||||||
| CAZyme ID | MGYG000001117_00783 | |||||||||||
| CAZy Family | CE11 | |||||||||||
| CAZyme Description | UDP-3-O-acyl-N-acetylglucosamine deacetylase | |||||||||||
| CAZyme Property |
|
|||||||||||
| Genome Property |
|
|||||||||||
| Gene Location | Start: 168058; End: 168900 Strand: + | |||||||||||
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| CE11 | 7 | 273 | 1.5e-99 | 0.992619926199262 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| pfam03331 | LpxC | 8.50e-147 | 7 | 274 | 1 | 271 | UDP-3-O-acyl N-acetylglycosamine deacetylase. The enzymes in this family catalyze the second step in the biosynthetic pathway for lipid A. |
| PRK13186 | lpxC | 7.57e-136 | 6 | 274 | 3 | 274 | UDP-3-O-acyl-N-acetylglucosamine deacetylase. |
| COG0774 | LpxC | 1.16e-115 | 6 | 272 | 3 | 275 | UDP-3-O-acyl-N-acetylglucosamine deacetylase [Cell wall/membrane/envelope biogenesis]. |
| PRK13188 | PRK13188 | 1.95e-106 | 1 | 280 | 1 | 306 | bifunctional UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase/(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase; Reviewed |
| TIGR00325 | lpxC | 1.42e-91 | 7 | 279 | 3 | 279 | UDP-3-0-acyl N-acetylglucosamine deacetylase. UDP-3-O-(R-3-hydroxymyristoyl)-GlcNAc deacetylase from E. coli , LpxC, was previously designated EnvA. This enzyme is involved in lipid-A precursor biosynthesis. It is essential for cell viability. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides] |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| QTV78319.1 | 9.18e-169 | 1 | 280 | 1 | 282 |
| QNP78243.1 | 6.97e-137 | 7 | 280 | 2 | 275 |
| BBG63219.1 | 8.03e-137 | 3 | 280 | 2 | 279 |
| ADB48045.1 | 9.63e-121 | 7 | 280 | 6 | 279 |
| AEQ22979.1 | 1.44e-116 | 7 | 276 | 6 | 276 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 5U39_A | 3.57e-71 | 7 | 274 | 6 | 278 | Pseudomonasaeruginosa LpxC in complex with CHIR-090 [Pseudomonas aeruginosa PAO1] |
| 4J3D_A | 3.79e-71 | 7 | 274 | 4 | 276 | Pseudomonasaeruginosa LpxC in complex with a hydroxamate inhibitor [Pseudomonas aeruginosa PAO1],4J3D_B Pseudomonas aeruginosa LpxC in complex with a hydroxamate inhibitor [Pseudomonas aeruginosa PAO1] |
| 5U3B_A | 4.03e-71 | 7 | 274 | 4 | 276 | Pseudomonasaeruginosa LpxC in complex with NVS-LPXC-01 [Pseudomonas aeruginosa PAO1],5U3B_B Pseudomonas aeruginosa LpxC in complex with NVS-LPXC-01 [Pseudomonas aeruginosa PAO1],6MAE_A CHAIN A. UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase PA-LPXC Complexed with (R)-3-((S)-3-(4-(cyclopropylethynyl)phenyl)-2-oxooxazolidin-5-yl)-N-hydroxy-2-methyl-2-(methylsulfonyl)propenamide [Pseudomonas aeruginosa PAO1] |
| 7K99_A | 4.55e-71 | 7 | 274 | 4 | 276 | CrystalStructure of P. aeruginosa LpxC with N-Hydroxyformamide inhibitor 19 [Pseudomonas aeruginosa PAO1],7K99_C Crystal Structure of P. aeruginosa LpxC with N-Hydroxyformamide inhibitor 19 [Pseudomonas aeruginosa PAO1],7K9A_A Crystal Structure of P. aeruginosa LpxC with N-Hydroxyformamide inhibitor [Pseudomonas aeruginosa PAO1],7K9A_C Crystal Structure of P. aeruginosa LpxC with N-Hydroxyformamide inhibitor [Pseudomonas aeruginosa PAO1] |
| 6MO4_A | 4.55e-71 | 7 | 274 | 8 | 280 | Co-Crystalstructure of P. aeruginosa LpxC-50067 complex [Pseudomonas aeruginosa PAO1] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| Q1D2K0 | 4.20e-74 | 7 | 274 | 8 | 278 | UDP-3-O-acyl-N-acetylglucosamine deacetylase OS=Myxococcus xanthus (strain DK1622) OX=246197 GN=lpxC PE=3 SV=1 |
| Q2S9Z8 | 7.52e-72 | 7 | 272 | 4 | 274 | UDP-3-O-acyl-N-acetylglucosamine deacetylase OS=Hahella chejuensis (strain KCTC 2396) OX=349521 GN=lpxC PE=3 SV=1 |
| Q4K6J9 | 3.11e-71 | 7 | 272 | 4 | 274 | UDP-3-O-acyl-N-acetylglucosamine deacetylase OS=Pseudomonas fluorescens (strain ATCC BAA-477 / NRRL B-23932 / Pf-5) OX=220664 GN=lpxC PE=3 SV=1 |
| C3KDE0 | 3.11e-71 | 7 | 272 | 4 | 274 | UDP-3-O-acyl-N-acetylglucosamine deacetylase OS=Pseudomonas fluorescens (strain SBW25) OX=216595 GN=lpxC PE=3 SV=1 |
| A1U3F2 | 6.41e-71 | 7 | 274 | 4 | 276 | UDP-3-O-acyl-N-acetylglucosamine deacetylase OS=Marinobacter nauticus (strain ATCC 700491 / DSM 11845 / VT8) OX=351348 GN=lpxC PE=3 SV=1 |
SignalP and Lipop Annotations help
This protein is predicted as OTHER
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 1.000036 | 0.000000 | 0.000000 | 0.000000 | 0.000000 | 0.000000 |