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CAZyme Information: MGYG000001097_00548

You are here: Home > Sequence: MGYG000001097_00548

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Prevotella pectinovora
Lineage Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae; Prevotella; Prevotella pectinovora
CAZyme ID MGYG000001097_00548
CAZy Family GT28
CAZyme Description UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
372 MGYG000001097_30|CGC1 39991.84 9.7039
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000001097 3372203 MAG China Asia
Gene Location Start: 28882;  End: 30000  Strand: +

Full Sequence      Download help

MDNELRIVIS  GGGTGGHIFP  AVSIANAIKA  KRPEAKILFV  GALGRMEMQR  VPAAGYEIKG60
LPVRGLIRPL  WSPKNIGVLI  DYLKSKGMAK  KIIKDFKPMA  AVGVGGYASG  ATLDAAHALG120
IPSLIQEQNS  YAGKTNKMLS  TKADKICVAY  DGMERFFPAD  KIMMTGNPVR  QNIVNAEISH180
EDAVKQFGLD  PEKKTILIVG  GSLGARTVNE  SVLAHLKEIK  ESGVQFIWQT  GKYYHESIMQ240
KMASHNDMPM  LKVMDFISDM  GAAYKAADLV  ISRAGASSIS  EFCLIGKPVI  LVPSPNVAED300
HQTKNAMALV  EKDAALMVKD  VEAKDKVIKL  ALTTVGDAAK  LESLATNVKK  LGLPHSADII360
ADEVLKLAEN  KK372

Enzyme Prediction      help

No EC number prediction in MGYG000001097_00548.

CAZyme Signature Domains help

Created with Snap1837557493111130148167186204223241260279297316334353195355GT28
Family Start End Evalue family coverage
GT28 195 355 1.8e-47 0.9872611464968153

CDD Domains      download full data without filtering help

Created with Snap18375574931111301481671862042232412602792973163343536370murG6363GT28_MurG6369MurG6364murG195358Glyco_tran_28_C
Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
PRK00726 murG 5.70e-136 6 370 3 357
undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional
cd03785 GT28_MurG 1.61e-128 6 363 1 350
undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase. MurG (EC 2.4.1.227) is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide (NAM). The resulting disaccharide is then transported across the cell membrane, where it is polymerized into NAG-NAM cell-wall repeat structure. MurG belongs to the GT-B structural superfamily of glycoslytransferases, which have characteristic N- and C-terminal domains, each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.
COG0707 MurG 1.11e-101 6 369 2 356
UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase [Cell wall/membrane/envelope biogenesis].
TIGR01133 murG 1.00e-98 6 364 2 348
undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase. RM 8449890 RT The final step of peptidoglycan subunit assembly in Escherichia coli occurs in the cytoplasm. RA Bupp K, van Heijenoort J. RL J Bacteriol 1993 Mar;175(6):1841-3 [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
pfam04101 Glyco_tran_28_C 1.94e-37 195 358 1 164
Glycosyltransferase family 28 C-terminal domain. The glycosyltransferase family 28 includes monogalactosyldiacylglycerol synthase (EC 2.4.1.46) and UDP-N-acetylglucosamine transferase (EC 2.4.1.-). Structural analysis suggests the C-terminal domain contains the UDP-GlcNAc binding site.

CAZyme Hits      help

Created with Snap18375574931111301481671862042232412602792973163343531368BCS85484.1|GT281368QNT67417.1|GT281372AGB27497.1|GT281367ASE16834.1|GT281367ADK95379.1|GT28
Hit ID E-Value Query Start Query End Hit Start Hit End
BCS85484.1 8.76e-193 1 368 1 366
QNT67417.1 2.51e-192 1 368 1 366
AGB27497.1 3.95e-185 1 372 1 371
ASE16834.1 2.37e-183 1 367 1 365
ADK95379.1 2.37e-183 1 367 1 365

PDB Hits      download full data without filtering help

Created with Snap183755749311113014816718620422324126027929731633435363677D1I_A63683S2U_A63681F0K_A
Hit ID E-Value Query Start Query End Hit Start Hit End Description
7D1I_A 5.33e-49 6 367 11 365
ChainA, UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [Acinetobacter baumannii],7D1I_B Chain B, UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [Acinetobacter baumannii],7D1I_C Chain C, UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [Acinetobacter baumannii]
3S2U_A 2.30e-46 6 368 4 355
Crystalstructure of the Pseudomonas aeruginosa MurG:UDP-GlcNAc substrate complex [Pseudomonas aeruginosa PAO1]
1F0K_A 2.36e-45 6 368 8 354
The1.9 Angstrom Crystal Structure Of E. Coli Murg [Escherichia coli],1F0K_B The 1.9 Angstrom Crystal Structure Of E. Coli Murg [Escherichia coli],1NLM_A Crystal Structure Of Murg:glcnac Complex [Escherichia coli],1NLM_B Crystal Structure Of Murg:glcnac Complex [Escherichia coli]

Swiss-Prot Hits      download full data without filtering help

Created with Snap18375574931111301481671862042232412602792973163343531369sp|A6L071|MURG_PHOV81369sp|Q8A258|MURG_BACTN3369sp|Q5LIJ7|MURG_BACFN3369sp|Q64ZM1|MURG_BACFR4371sp|A6LEU3|MURG_PARD8
Hit ID E-Value Query Start Query End Hit Start Hit End Description
A6L071 1.11e-165 1 369 1 368
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Phocaeicola vulgatus (strain ATCC 8482 / DSM 1447 / JCM 5826 / CCUG 4940 / NBRC 14291 / NCTC 11154) OX=435590 GN=murG PE=3 SV=1
Q8A258 3.48e-161 1 369 1 369
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / JCM 5827 / CCUG 10774 / NCTC 10582 / VPI-5482 / E50) OX=226186 GN=murG PE=3 SV=1
Q5LIJ7 1.87e-160 3 369 12 378
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Bacteroides fragilis (strain ATCC 25285 / DSM 2151 / CCUG 4856 / JCM 11019 / NCTC 9343 / Onslow) OX=272559 GN=murG PE=3 SV=2
Q64ZM1 1.87e-160 3 369 12 378
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Bacteroides fragilis (strain YCH46) OX=295405 GN=murG PE=3 SV=1
A6LEU3 6.17e-144 4 371 3 368
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Parabacteroides distasonis (strain ATCC 8503 / DSM 20701 / CIP 104284 / JCM 5825 / NCTC 11152) OX=435591 GN=murG PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
1.000062 0.000000 0.000000 0.000000 0.000000 0.000000

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000001097_00548.