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CAZyme Information: MGYG000000922_01359
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | UMGS416 sp900542005 | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Firmicutes_A; Clostridia_A; Christensenellales; UMGS416; UMGS416; UMGS416 sp900542005 | |||||||||||
| CAZyme ID | MGYG000000922_01359 | |||||||||||
| CAZy Family | GT39 | |||||||||||
| CAZyme Description | hypothetical protein | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 37358; End: 41128 Strand: + | |||||||||||
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| GT39 | 844 | 1066 | 1.8e-56 | 0.9237668161434978 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| pfam16192 | PMT_4TMC | 1.24e-25 | 1078 | 1250 | 4 | 198 | C-terminal four TMM region of protein-O-mannosyltransferase. PMT_4TMC is the C-terminal four membrane-pass region of protein-O-mannosyltransferases and similar enzymes. |
| COG1928 | PMT1 | 2.10e-21 | 1078 | 1254 | 502 | 695 | Dolichyl-phosphate-mannose--protein O-mannosyl transferase [Posttranslational modification, protein turnover, chaperones]. |
| COG5542 | COG5542 | 2.09e-18 | 270 | 628 | 70 | 405 | Mannosyltransferase related to Gpi18 [Carbohydrate transport and metabolism]. |
| COG4346 | COG4346 | 3.75e-18 | 863 | 1202 | 126 | 407 | Predicted membrane-bound dolichyl-phosphate-mannose-protein mannosyltransferase [Posttranslational modification, protein turnover, chaperones]. |
| pfam02366 | PMT | 3.20e-17 | 840 | 1065 | 13 | 239 | Dolichyl-phosphate-mannose-protein mannosyltransferase. This is a family of Dolichyl-phosphate-mannose-protein mannosyltransferase proteins EC:2.4.1.109. These proteins are responsible for O-linked glycosylation of proteins, they catalyze the reaction:- Dolichyl phosphate D-mannose + protein <=> dolichyl phosphate + O-D-mannosyl-protein. Also in this family is Drosophila rotated abdomen protein which is a putative mannosyltransferase. This family appears to be distantly related to pfam02516 (A Bateman pers. obs.). This family also contains sequences from ArnTs (4-amino-4-deoxy-L-arabinose lipid A transferase). They catalyze the addition of 4-amino-4-deoxy-l-arabinose (l-Ara4N) to the lipid A moiety of the lipopolysaccharide. This is a critical modification enabling bacteria (e.g. Escherichia coli and Salmonella typhimurium) to resist killing by antimicrobial peptides such as polymyxins. Members such as undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase are predicted to have 12 trans-membrane regions. The N-terminal portion of these proteins is hypothesized to have a conserved glycosylation activity which is shared between distantly related oligosaccharyltransferases ArnT and PglB families. |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| CQR52353.1 | 4.24e-243 | 29 | 1254 | 30 | 1275 |
| QNK56024.1 | 8.21e-242 | 29 | 1254 | 31 | 1271 |
| QWU18200.1 | 6.30e-234 | 29 | 1254 | 32 | 1273 |
| AHV95529.1 | 2.47e-233 | 6 | 1254 | 12 | 1273 |
| BCG57259.1 | 7.05e-233 | 29 | 1254 | 31 | 1274 |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| L8F4Z2 | 8.84e-41 | 841 | 1252 | 58 | 515 | Probable dolichyl-phosphate-mannose--protein mannosyltransferase OS=Mycolicibacterium smegmatis (strain MKD8) OX=1214915 GN=pmt PE=3 SV=1 |
| P9WN04 | 4.84e-33 | 850 | 1252 | 73 | 521 | Probable dolichyl-phosphate-mannose--protein mannosyltransferase OS=Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh) OX=83331 GN=pmt PE=3 SV=2 |
| P9WN05 | 4.84e-33 | 850 | 1252 | 73 | 521 | Probable dolichyl-phosphate-mannose--protein mannosyltransferase OS=Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) OX=83332 GN=pmt PE=1 SV=2 |
| Q8NRZ6 | 3.19e-25 | 850 | 1252 | 64 | 519 | Probable dolichyl-phosphate-mannose--protein mannosyltransferase OS=Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025) OX=196627 GN=pmt PE=3 SV=1 |
SignalP and Lipop Annotations help
This protein is predicted as SP
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 0.000598 | 0.560976 | 0.437769 | 0.000267 | 0.000196 | 0.000179 |
TMHMM Annotations download full data without filtering help
| start | end |
|---|---|
| 5 | 27 |
| 207 | 224 |
| 245 | 267 |
| 323 | 345 |
| 358 | 380 |
| 407 | 429 |
| 442 | 464 |
| 479 | 501 |
| 508 | 530 |
| 540 | 559 |
| 582 | 601 |
| 611 | 633 |
| 683 | 700 |
| 892 | 914 |
| 921 | 938 |
| 943 | 965 |
| 977 | 994 |
| 999 | 1021 |
| 1042 | 1064 |
| 1126 | 1148 |
| 1161 | 1178 |
| 1182 | 1201 |
| 1214 | 1236 |