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CAZyme Information: MGYG000000875_00286

You are here: Home > Sequence: MGYG000000875_00286

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species CAG-1024 sp000432015
Lineage Bacteria; Firmicutes_A; Clostridia_A; Christensenellales; CAG-138; CAG-1024; CAG-1024 sp000432015
CAZyme ID MGYG000000875_00286
CAZy Family GT39
CAZyme Description hypothetical protein
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
1278 MGYG000000875_5|CGC1 142067.6 7.6688
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000000875 1875451 MAG United States North America
Gene Location Start: 13026;  End: 16862  Strand: +

Full Sequence      Download help

Enzyme Prediction      help

No EC number prediction in MGYG000000875_00286.

CAZyme Signature Domains help

Family Start End Evalue family coverage
GT39 853 1076 7.2e-55 0.9192825112107623

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
pfam16192 PMT_4TMC 8.74e-22 1104 1251 10 179
C-terminal four TMM region of protein-O-mannosyltransferase. PMT_4TMC is the C-terminal four membrane-pass region of protein-O-mannosyltransferases and similar enzymes.
COG5542 COG5542 2.02e-16 269 584 50 351
Mannosyltransferase related to Gpi18 [Carbohydrate transport and metabolism].
COG1928 PMT1 6.09e-16 1087 1265 491 687
Dolichyl-phosphate-mannose--protein O-mannosyl transferase [Posttranslational modification, protein turnover, chaperones].
COG1928 PMT1 1.01e-14 858 1073 50 264
Dolichyl-phosphate-mannose--protein O-mannosyl transferase [Posttranslational modification, protein turnover, chaperones].
pfam02366 PMT 6.22e-13 851 1075 16 239
Dolichyl-phosphate-mannose-protein mannosyltransferase. This is a family of Dolichyl-phosphate-mannose-protein mannosyltransferase proteins EC:2.4.1.109. These proteins are responsible for O-linked glycosylation of proteins, they catalyze the reaction:- Dolichyl phosphate D-mannose + protein <=> dolichyl phosphate + O-D-mannosyl-protein. Also in this family is Drosophila rotated abdomen protein which is a putative mannosyltransferase. This family appears to be distantly related to pfam02516 (A Bateman pers. obs.). This family also contains sequences from ArnTs (4-amino-4-deoxy-L-arabinose lipid A transferase). They catalyze the addition of 4-amino-4-deoxy-l-arabinose (l-Ara4N) to the lipid A moiety of the lipopolysaccharide. This is a critical modification enabling bacteria (e.g. Escherichia coli and Salmonella typhimurium) to resist killing by antimicrobial peptides such as polymyxins. Members such as undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase are predicted to have 12 trans-membrane regions. The N-terminal portion of these proteins is hypothesized to have a conserved glycosylation activity which is shared between distantly related oligosaccharyltransferases ArnT and PglB families.

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
QGQ95357.1 1.28e-242 26 1262 33 1266
QSF45552.1 4.22e-242 2 1256 6 1254
CQR52353.1 6.28e-242 6 1270 11 1271
QWT55655.1 9.45e-239 129 1264 99 1242
ASA25569.1 1.45e-237 1 1268 5 1261

PDB Hits      help

has no PDB hit.

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
P9WN04 1.03e-27 858 1264 73 514
Probable dolichyl-phosphate-mannose--protein mannosyltransferase OS=Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh) OX=83331 GN=pmt PE=3 SV=2
P9WN05 1.03e-27 858 1264 73 514
Probable dolichyl-phosphate-mannose--protein mannosyltransferase OS=Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) OX=83332 GN=pmt PE=1 SV=2
L8F4Z2 1.78e-24 858 1261 67 504
Probable dolichyl-phosphate-mannose--protein mannosyltransferase OS=Mycolicibacterium smegmatis (strain MKD8) OX=1214915 GN=pmt PE=3 SV=1
Q8NRZ6 3.90e-14 881 1223 99 463
Probable dolichyl-phosphate-mannose--protein mannosyltransferase OS=Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025) OX=196627 GN=pmt PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as SP

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
0.000219 0.999159 0.000150 0.000173 0.000142 0.000134

TMHMM  Annotations      download full data without filtering help

start end
223 245
260 282
302 324
339 361
368 390
394 413
434 451
461 479
492 514
529 551
558 577
581 596
601 623
638 660
702 724
900 922
956 978
998 1020
1056 1078
1145 1167
1180 1197
1202 1224
1236 1258