You are browsing environment: HUMAN GUT
CAZyme Information: MGYG000000454_00768
You are here: Home > Sequence: MGYG000000454_00768
Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Firmicutes_A; Clostridia; Oscillospirales; CAG-272; RUG11130; | |||||||||||
| CAZyme ID | MGYG000000454_00768 | |||||||||||
| CAZy Family | GH27 | |||||||||||
| CAZyme Description | Alpha-galactosidase A | |||||||||||
| CAZyme Property |
|
|||||||||||
| Genome Property |
|
|||||||||||
| Gene Location | Start: 311; End: 1438 Strand: + | |||||||||||
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| GH27 | 101 | 346 | 4.9e-58 | 0.9737991266375546 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| cd14792 | GH27 | 1.80e-135 | 6 | 279 | 1 | 271 | glycosyl hydrolase family 27 (GH27). GH27 enzymes occur in eukaryotes, prokaryotes, and archaea with a wide range of hydrolytic activities, including alpha-glucosidase (glucoamylase and sucrase-isomaltase), alpha-N-acetylgalactosaminidase, and 3-alpha-isomalto-dextranase. All GH27 enzymes cleave a terminal carbohydrate moiety from a substrate that varies considerably in size, depending on the enzyme, and may be either a starch or a glycoprotein. GH27 members are retaining enzymes that cleave their substrates via an acid/base-catalyzed, double-displacement mechanism involving a covalent glycosyl-enzyme intermediate. Two aspartic acid residues have been identified as the catalytic nucleophile and the acid/base, respectively. |
| PLN02808 | PLN02808 | 1.31e-91 | 6 | 368 | 32 | 381 | alpha-galactosidase |
| PLN02229 | PLN02229 | 3.31e-90 | 6 | 369 | 63 | 416 | alpha-galactosidase |
| PLN02692 | PLN02692 | 1.34e-80 | 6 | 294 | 56 | 334 | alpha-galactosidase |
| pfam16499 | Melibiase_2 | 3.68e-79 | 6 | 279 | 2 | 284 | Alpha galactosidase A. |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| AEE96273.1 | 2.30e-148 | 1 | 368 | 1 | 370 |
| QTE68632.1 | 1.79e-147 | 1 | 369 | 1 | 388 |
| QAA34453.1 | 2.68e-144 | 1 | 368 | 1 | 368 |
| QTE71472.1 | 3.04e-144 | 1 | 369 | 4 | 391 |
| QTE75438.1 | 3.04e-144 | 1 | 369 | 4 | 391 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 1UAS_A | 5.26e-79 | 6 | 369 | 9 | 358 | ChainA, alpha-galactosidase [Oryza sativa] |
| 4OGZ_A | 2.55e-76 | 3 | 369 | 97 | 471 | Crystalstructure of a putative alpha-galactosidase/melibiase (BF4189) from Bacteroides fragilis NCTC 9343 at 2.00 A resolution [Bacteroides fragilis NCTC 9343],4OGZ_B Crystal structure of a putative alpha-galactosidase/melibiase (BF4189) from Bacteroides fragilis NCTC 9343 at 2.00 A resolution [Bacteroides fragilis NCTC 9343] |
| 4NZJ_A | 2.83e-76 | 3 | 369 | 97 | 472 | Crystalstructure of a putative alpha-galactosidase (BF1418) from Bacteroides fragilis NCTC 9343 at 1.57 A resolution [Bacteroides fragilis NCTC 9343] |
| 6F4C_B | 1.05e-72 | 6 | 369 | 9 | 359 | Nicotianabenthamiana alpha-galactosidase [Nicotiana benthamiana] |
| 3A5V_A | 8.45e-71 | 6 | 367 | 9 | 387 | Crystalstructure of alpha-galactosidase I from Mortierella vinacea [Umbelopsis vinacea] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| P14749 | 1.37e-82 | 6 | 369 | 56 | 406 | Alpha-galactosidase OS=Cyamopsis tetragonoloba OX=3832 PE=1 SV=1 |
| Q8RX86 | 2.76e-78 | 5 | 368 | 39 | 389 | Alpha-galactosidase 2 OS=Arabidopsis thaliana OX=3702 GN=AGAL2 PE=1 SV=1 |
| Q9FXT4 | 1.40e-77 | 6 | 369 | 64 | 413 | Alpha-galactosidase OS=Oryza sativa subsp. japonica OX=39947 GN=Os10g0493600 PE=1 SV=1 |
| Q8VXZ7 | 1.73e-77 | 6 | 369 | 73 | 426 | Alpha-galactosidase 3 OS=Arabidopsis thaliana OX=3702 GN=AGAL3 PE=1 SV=1 |
| Q42656 | 3.58e-74 | 6 | 369 | 24 | 374 | Alpha-galactosidase OS=Coffea arabica OX=13443 PE=1 SV=1 |
SignalP and Lipop Annotations help
This protein is predicted as OTHER
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 1.000067 | 0.000003 | 0.000000 | 0.000000 | 0.000000 | 0.000000 |