CAZyme Information: MGYG000000440_00990

Basic Information

• Lineage: Bacteria; Firmicutes_A; Clostridia; Oscillospirales; CAG-272; UMGS1865
• CAZyme ID: MGYG000000440_00990
• CAZy Family: GH36
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
550		62819.92	5.1032

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000000440	2422037	MAG	Sweden	Europe

• Gene Location: Start: 113378; End: 115030 Strand: -

Full Sequence      

MWYNHCVTDYTPHEGDSIMQIRFPDIYWVYGENGKRILSSDENGDGAGVSMKLYFERDNL
IPAITADDVPLCYVVLKWFFRDGERRAEPIHVLGDAWERAYGDLSWQGIVPERCMPWYCM
VSNGTDSNPCYDGRYTECFGVRVRPSSFAFWQYDDGGVTLTLDIRCGGRGVLLGGRSLRA
AEILFRDYRDCSAYQSGKRFCGKLCGDPIFPREPVYGFNNFYYAYGVSSAEEVLRDAAKL
ADCTKGLHKPYMVIDDCWQPNPCDGPWDHGNEKFPDMKGLAEQMTEMGVNPGIWLRPLSQ
MALLDLPQVCRSERNGCFLDPSDDGTLEYIKTQFSRLVGWGYRLIKFDFVTYDLFGKWGW
ECPGFLADGNWSFRDRSKTSAEIILRLYRAIREASGDAVLIGCNAIGHLCAGLVEINRTG
DDTSGRDWRRTRQFGVNTLAFRSIQNGTFYASDADCVGLTGLVPWKLNQRWMHMLAHSGT
PLFISWDPSQDTEEVRAAVCKALRVNSRQEDRLIPLDWMENNCPRRWSLNGEEVTVDWFG
HYASDQIEKR

Enzyme Prediction     

No EC number prediction in MGYG000000440_00990.

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
cd14791	GH36	8.02e-39	213	504	1	295	glycosyl hydrolase family 36 (GH36). GH36 enzymes occur in prokaryotes, eukaryotes, and archaea with a wide range of hydrolytic activities, including alpha-galactosidase, alpha-N-acetylgalactosaminidase, stachyose synthase, and raffinose synthase. All GH36 enzymes cleave a terminal carbohydrate moiety from a substrate that varies considerably in size, depending on the enzyme, and may be either a starch or a glycoprotein. GH36 members are retaining enzymes that cleave their substrates via an acid/base-catalyzed, double-displacement mechanism involving a covalent glycosyl-enzyme intermediate. Two aspartic acid residues have been identified as the catalytic nucleophile and the acid/base, respectively.
cd14790	GH_D	1.10e-10	222	504	8	250	Glycoside hydrolases, clan D. This group of glycosyl hydrolase families is comprised of glycosyl hydrolase family 31 (GH31), family 36 (GH36), and family 27 (GH27). These structurally and mechanistically related protein families are retaining enzymes that cleave their substrates via an acid/base-catalyzed, double-displacement mechanism involving a covalent glycosyl-enzyme intermediate. Two aspartic acid residues have been identified as the catalytic nucleophile and the acid/base, respectively. They have a wide range of functions including alpha-glucosidase, alpha-xylosidase, 6-alpha-glucosyltransferase, 3-alpha-isomaltosyltransferase, alpha-N-acetylgalactosaminidase, stachyose synthase, raffinose synthase, and alpha-1,4-glucan lyase.
COG3345	GalA	9.27e-06	211	349	289	451	Alpha-galactosidase [Carbohydrate transport and metabolism].
cd14792	GH27	9.70e-06	214	497	1	258	glycosyl hydrolase family 27 (GH27). GH27 enzymes occur in eukaryotes, prokaryotes, and archaea with a wide range of hydrolytic activities, including alpha-glucosidase (glucoamylase and sucrase-isomaltase), alpha-N-acetylgalactosaminidase, and 3-alpha-isomalto-dextranase. All GH27 enzymes cleave a terminal carbohydrate moiety from a substrate that varies considerably in size, depending on the enzyme, and may be either a starch or a glycoprotein. GH27 members are retaining enzymes that cleave their substrates via an acid/base-catalyzed, double-displacement mechanism involving a covalent glycosyl-enzyme intermediate. Two aspartic acid residues have been identified as the catalytic nucleophile and the acid/base, respectively.
cd06592	GH31_NET37	1.24e-05	252	297	37	80	glucosidase NET37. NET37 (also known as KIAA1161) is a human lamina-associated nuclear envelope transmembrane protein. A member of the glycosyl hydrolase family 31 (GH31) , it has been shown to be required for myogenic differentiation of C2C12 cells. Related proteins are found in eukaryotes and prokaryotes. Enzymes of the GH31 family possess a wide range of different hydrolytic activities including alpha-glucosidase (glucoamylase and sucrase-isomaltase), alpha-xylosidase, 6-alpha-glucosyltransferase, 3-alpha-isomaltosyltransferase and alpha-1,4-glucan lyase. All GH31 enzymes cleave a terminal carbohydrate moiety from a substrate that varies considerably in size, depending on the enzyme, and may be either a starch or a glycoprotein.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
SNU96820.1	1.41e-160	18	539	5	523
BDA09953.1	3.12e-160	17	539	4	526
QIB59833.1	2.51e-159	17	539	4	526
QGQ95278.1	2.50e-156	27	538	10	519
ANE49069.1	5.61e-156	91	539	23	474

PDB Hits     

has no PDB hit.

Swiss-Prot Hits     

has no Swissprot hit.

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
1.000067	0.000003	0.000000	0.000000	0.000000	0.000000

TMHMM  Annotations     

There is no transmembrane helices in MGYG000000440_00990.