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CAZyme Information: MGYG000000147_03325
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | Bacillus paralicheniformis | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus; Bacillus paralicheniformis | |||||||||||
| CAZyme ID | MGYG000000147_03325 | |||||||||||
| CAZy Family | GT2 | |||||||||||
| CAZyme Description | Plipastatin synthase subunit E | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 163260; End: 167063 Strand: - | |||||||||||
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| cd12117 | A_NRPS_Srf_like | 0.0 | 473 | 951 | 1 | 483 | The adenylation domain of nonribosomal peptide synthetases (NRPS), including Bacillus subtilis termination module Surfactin (SrfA-C). The adenylation (A) domain of NRPS recognizes a specific amino acid or hydroxy acid and activates it as an (amino) acyl adenylate by hydrolysis of ATP. The activated acyl moiety then forms a thioester to the enzyme-bound cofactor phosphopantetheine of a peptidyl carrier protein domain. NRPSs are large multifunctional enzymes which synthesize many therapeutically useful peptides in bacteria and fungi via a template-directed, nucleic acid independent nonribosomal mechanism. These natural products include antibiotics, immunosuppressants, plant and animal toxins, and enzyme inhibitors. NRPS has a distinct modular structure in which each module is responsible for the recognition, activation, and, in some cases, modification of a single amino acid residue of the final peptide product. The modules can be subdivided into domains that catalyze specific biochemical reactions. This family includes the adenylation domain of the Bacillus subtilis termination module (Surfactin domain, SrfA-C) which recognizes a specific amino acid building block, which is then activated and transferred to the terminal thiol of the 4'-phosphopantetheine (Ppan) arm of the downstream peptidyl carrier protein (PCP) domain. |
| PRK12316 | PRK12316 | 0.0 | 7 | 1054 | 1553 | 2602 | peptide synthase; Provisional |
| PRK12316 | PRK12316 | 0.0 | 12 | 1033 | 51 | 1081 | peptide synthase; Provisional |
| PRK12316 | PRK12316 | 0.0 | 7 | 1036 | 4099 | 5139 | peptide synthase; Provisional |
| PRK12316 | PRK12316 | 0.0 | 12 | 1033 | 2604 | 3619 | peptide synthase; Provisional |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| QND46664.1 | 4.51e-159 | 10 | 1154 | 1614 | 2791 |
| BAZ00088.1 | 1.54e-158 | 13 | 1147 | 2247 | 3413 |
| BAZ75991.1 | 1.54e-158 | 13 | 1147 | 2247 | 3413 |
| BAY30132.1 | 9.39e-158 | 13 | 1147 | 2249 | 3415 |
| BAY90071.1 | 1.04e-156 | 13 | 1147 | 2238 | 3404 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 2VSQ_A | 0.0 | 6 | 1256 | 8 | 1267 | Structureof surfactin A synthetase C (SrfA-C), a nonribosomal peptide synthetase termination module [Bacillus subtilis] |
| 6P1J_A | 2.33e-134 | 11 | 951 | 6 | 964 | Thestructure of condensation and adenylation domains of teixobactin-producing nonribosomal peptide synthetase Txo2 serine module [Eleftheria terrae],6P1J_B The structure of condensation and adenylation domains of teixobactin-producing nonribosomal peptide synthetase Txo2 serine module [Eleftheria terrae] |
| 1AMU_A | 2.45e-126 | 450 | 983 | 20 | 556 | PhenylalanineActivating Domain Of Gramicidin Synthetase 1 In A Complex With Amp And Phenylalanine [Brevibacillus brevis],1AMU_B Phenylalanine Activating Domain Of Gramicidin Synthetase 1 In A Complex With Amp And Phenylalanine [Brevibacillus brevis] |
| 4ZXH_A | 8.43e-123 | 107 | 1176 | 107 | 1182 | ChainA, ABBFA_003403 [Acinetobacter baumannii AB307-0294],4ZXI_A Chain A, Tyrocidine synthetase 3 [Acinetobacter baumannii AB307-0294] |
| 7LY7_A | 4.47e-122 | 11 | 1036 | 11 | 1016 | ChainA, BmdB, Bacillamide NRPS [Thermoactinomyces vulgaris] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| Q08787 | 0.0 | 6 | 1256 | 8 | 1267 | Surfactin synthase subunit 3 OS=Bacillus subtilis (strain 168) OX=224308 GN=srfAC PE=1 SV=2 |
| O31827 | 0.0 | 1 | 1256 | 8 | 1266 | Plipastatin synthase subunit E OS=Bacillus subtilis (strain 168) OX=224308 GN=ppsE PE=1 SV=1 |
| Q9R9I9 | 3.63e-303 | 3 | 1256 | 1318 | 2581 | Mycosubtilin synthase subunit C OS=Bacillus subtilis OX=1423 GN=mycC PE=3 SV=1 |
| O68006 | 2.17e-266 | 6 | 1044 | 4205 | 5245 | Bacitracin synthase 1 OS=Bacillus licheniformis OX=1402 GN=bacA PE=3 SV=1 |
| Q04747 | 3.46e-264 | 5 | 1048 | 4 | 1057 | Surfactin synthase subunit 2 OS=Bacillus subtilis (strain 168) OX=224308 GN=srfAB PE=1 SV=3 |
SignalP and Lipop Annotations help
This protein is predicted as OTHER
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 1.000056 | 0.000000 | 0.000000 | 0.000000 | 0.000000 | 0.000000 |