Browse dbCAN-PUL Entries

PULID Characterization Method(s) Substrate Organism Publication Publish Date Type Num Genes Num CAZymes CazyFamily
PUL0115 expression of recombinant proteins, RNA-seq, differential gene expression host glycan Bacteroides thetaiotaomicron <a href=https://pubmed.ncbi.nlm.nih.gov/31160824/>31160824</a>
Complex N-glycan breakdown by gut Bacteroides involves an extensive enzymatic apparatus encoded by multiple co-regulated genetic loci. Nat Microbiol. 2019 Sep;4(9):1571-1581. doi: 10.1038/s41564-019-0466-x. Epub 2019 Jun 3.
2019 Sep degradation 7 7 CBM93, GH33, CE3, CE20, GH2, GH20, GH20, CBM32
PUL0116 expression of recombinant proteins, RNA-seq, differential gene expression host glycan Bacteroides thetaiotaomicron <a href=https://pubmed.ncbi.nlm.nih.gov/31160824/>31160824</a>
Complex N-glycan breakdown by gut Bacteroides involves an extensive enzymatic apparatus encoded by multiple co-regulated genetic loci. Nat Microbiol. 2019 Sep;4(9):1571-1581. doi: 10.1038/s41564-019-0466-x. Epub 2019 Jun 3.
2019 Sep degradation 2 1 GH20
PUL0117 expression of recombinant proteins, RNA-seq, differential gene expression, enzyme specificity assay, enzyme activity assay host glycan Bacteroides thetaiotaomicron <a href=https://pubmed.ncbi.nlm.nih.gov/31160824/>31160824</a>, <a href=https://pubmed.ncbi.nlm.nih.gov/23943617/>23943617</a>
Complex N-glycan breakdown by gut Bacteroides involves an extensive enzymatic apparatus encoded by multiple co-regulated genetic loci. Discovery of beta-1,4-D-mannosyl-N-acetyl-D-glucosamine phosphorylase involved in the metabolism of N-glycans. Nat Microbiol. 2019 Sep;4(9):1571-1581. doi: 10.1038/s41564-019-0466-x. Epub 2019 Jun 3. J Biol Chem. 2013 Sep 20;288(38):27366-27374. doi: 10.1074/jbc.M113.469080. Epub 2013 Aug 13.
2019 Sep,2013 Sep 20 degradation 22 7 GH130_2, GH163, GH18, GH20, GH92
PUL0120 expression of recombinant proteins, RNA-seq, differential gene expression host glycan Bacteroides thetaiotaomicron <a href=https://pubmed.ncbi.nlm.nih.gov/31160824/>31160824</a>
Complex N-glycan breakdown by gut Bacteroides involves an extensive enzymatic apparatus encoded by multiple co-regulated genetic loci. Nat Microbiol. 2019 Sep;4(9):1571-1581. doi: 10.1038/s41564-019-0466-x. Epub 2019 Jun 3.
2019 Sep degradation 6 1 GH18
PUL0467 microarray, qPCR, expression of recombinant proteins, RNA-seq, differential gene expression host glycan Bacteroides thetaiotaomicron <a href=https://pubmed.ncbi.nlm.nih.gov/18996345/>18996345</a>, <a href=https://pubmed.ncbi.nlm.nih.gov/31160824/>31160824</a>
Mucosal glycan foraging enhances fitness and transmission of a saccharolytic human gut bacterial symbiont. Complex N-glycan breakdown by gut Bacteroides involves an extensive enzymatic apparatus encoded by multiple co-regulated genetic loci. Cell Host Microbe. 2008 Nov 13;4(5):447-57. doi: 10.1016/j.chom.2008.09.007. Nat Microbiol. 2019 Sep;4(9):1571-1581. doi: 10.1038/s41564-019-0466-x. Epub 2019 Jun 3.
2008 Nov 13,2019 Sep degradation 14 4 GH18, GH2, GH20, GH29, CBM32