Browse dbCAN-PUL Entries

PULID Characterization Method(s) Substrate Organism Publication Publish Date Type Num Genes Num CAZymes CazyFamily
PUL0608 enzyme activity assay, clone and expression, liquid chromatography and mass spectrometry, thin-layer chromatography, MALDI-TOF/MS human milk oligosaccharide Roseburia hominis DSM 16839 <a href=https://pubmed.ncbi.nlm.nih.gov/32620774/>32620774</a>
Butyrate producing colonic Clostridiales metabolise human milk oligosaccharides and cross feed on mucin via conserved pathways. Nat Commun. 2020 Jul 3;11(1):3285. doi: 10.1038/s41467-020-17075-x.
2020 Jul 3 degradation 9 2 GH112, GH136
PUL0609 enzyme activity assay, clone and expression, liquid chromatography and mass spectrometry, thin-layer chromatography, MALDI-TOF/MS human milk oligosaccharide Roseburia inulinivorans DSM 16841 <a href=https://pubmed.ncbi.nlm.nih.gov/32620774/>32620774</a>
Butyrate producing colonic Clostridiales metabolise human milk oligosaccharides and cross feed on mucin via conserved pathways. Nat Commun. 2020 Jul 3;11(1):3285. doi: 10.1038/s41467-020-17075-x.
2020 Jul 3 degradation 11 4 GH112, GH136, CBM32, GH95
PUL0793 enzyme activity assay, quantification of reaction product reducing ends, RNA-seq, differential gene expression, NMR, MALDI-TOF/MS, gas chromatography, mass spectrometry, bicinchoninic acid (BCA) assay, recombinant protein expression arabinan Bacteroides intestinalis DSM 17393 <a href=https://pubmed.ncbi.nlm.nih.gov/39443715/>39443715</a>
In vivo manipulation of human gut Bacteroides fitness by abiotic oligosaccharides. Nat Chem Biol. 2025 Apr;21(4):544-554. doi: 10.1038/s41589-024-01763-6. Epub 2024 Oct 23.
2025 Apr degradation 14 6 CE1, GH127, GH146, GH43_34, CBM32, GH97
PUL0794 enzyme activity assay, quantification of reaction product reducing ends, RNA-seq, differential gene expression, NMR, MALDI-TOF/MS, gas chromatography, mass spectrometry, bicinchoninic acid (BCA) assay, recombinant protein expression arabinan Bacteroides intestinalis DSM 17393 <a href=https://pubmed.ncbi.nlm.nih.gov/39443715/>39443715</a>
In vivo manipulation of human gut Bacteroides fitness by abiotic oligosaccharides. Nat Chem Biol. 2025 Apr;21(4):544-554. doi: 10.1038/s41589-024-01763-6. Epub 2024 Oct 23.
2025 Apr degradation 23 8 GH146, GH28, GH43_29, GH43_4, GH51_1, GH51_2, GH97