Browse dbCAN-PUL Entries

PULID Characterization Method(s) Substrate Organism Publication Publish Date Type Num Genes Num CAZymes CazyFamily
PUL0190 RNA-seq, RT-PCR, qPCR pectin Bacteroides xylanisolvens <a href=https://pubmed.ncbi.nlm.nih.gov/26920945/>26920945</a>
Unraveling the pectinolytic function of Bacteroides xylanisolvens using a RNA-seq approach and mutagenesis. BMC Genomics. 2016 Feb 27;17:147. doi: 10.1186/s12864-016-2472-1.
2016 Feb 27 degradation 15 6 GH146, GH43_29, GH43_4, GH51_1, GH51_2
PUL0218 enzyme activity assay arabinan termite gut metagenome <a href=https://pubmed.ncbi.nlm.nih.gov/25304507/>25304507</a>
Investigating the function of an arabinan utilization locus isolated from a termite gut community. Appl Environ Microbiol. 2015 Jan;81(1):31-9. doi: 10.1128/AEM.02257-14. Epub 2014 Oct 10.
2015 Jan degradation 24 5 GH146, GH97, GH43_4, GH51_1, GH51_2, GH43_29
PUL0300 gene trait matching exercise arabinoxylan Bifidobacterium longum <a href=https://pubmed.ncbi.nlm.nih.gov/29310579/>29310579</a>
Gene-trait matching across the Bifidobacterium longum pan-genome reveals considerable diversity in carbohydrate catabolism among human infant strains. BMC Genomics. 2018 Jan 8;19(1):33. doi: 10.1186/s12864-017-4388-9.
2018 Jan 8 degradation 14 5 GH43_26, GH43_27, GH43_4, GH51_2
PUL0302 RT-qPCR, isothermal titration calorimetry (ITC), enzyme activity assay, gene deletion mutant and growth assay, high-performance anion-exchange chromatography arabinan Bacteroides thetaiotaomicron <a href=https://pubmed.ncbi.nlm.nih.gov/29255254/>29255254</a>, <a href=https://pubmed.ncbi.nlm.nih.gov/22686399/>22686399</a>, <a href=https://pubmed.ncbi.nlm.nih.gov/21339299/>21339299</a>
Dietary pectic glycans are degraded by coordinated enzyme pathways in human colonic Bacteroides. Prioritization of a plant polysaccharide over a mucus carbohydrate is enforced by a Bacteroides hybrid two-component system. The structure and function of an arabinan-specific alpha-1,2-arabinofuranosidase identified from screening the activities of bacterial GH43 glycoside hydrolases. Nat Microbiol. 2018 Feb;3(2):210-219. doi: 10.1038/s41564-017-0079-1. Epub 2017 Dec 18. Mol Microbiol. 2012 Aug;85(3):478-91. doi: 10.1111/j.1365-2958.2012.08123.x. Epub 2012 Jul 5. J Biol Chem. 2011 Apr 29;286(17):15483-95. doi: 10.1074/jbc.M110.215962. Epub 2011 Feb 21.
2018 Feb,2012 Aug,2011 Apr 29 degradation 22 6 GH146, GH43_29, GH43_4, GH51_1, GH51_2
PUL0479 growth assay pectin Flavobacterium johnsoniae <a href=https://pubmed.ncbi.nlm.nih.gov/19717629/>19717629</a>
Novel features of the polysaccharide-digesting gliding bacterium Flavobacterium johnsoniae as revealed by genome sequence analysis. Appl Environ Microbiol. 2009 Nov;75(21):6864-75. doi: 10.1128/AEM.01495-09. Epub 2009 Aug 28.
2009 Nov degradation 20 11 GH2, GH27, GH28, GH43_19, GH43_34, GH51_2, GH89, GH92, GH95
PUL0532 RNA-seq arabinan Bacteroides cellulosilyticus <a href=https://pubmed.ncbi.nlm.nih.gov/23976882/>23976882</a>
Effects of diet on resource utilization by a model human gut microbiota containing Bacteroides cellulosilyticus WH2, a symbiont with an extensive glycobiome. PLoS Biol. 2013;11(8):e1001637. doi: 10.1371/journal.pbio.1001637. Epub 2013 Aug 20.
2013 degradation 17 5 GH146, GH43_4, GH51_1, GH51_2
PUL0546 RNA-seq arabinogalactan Bacteroides cellulosilyticus <a href=https://pubmed.ncbi.nlm.nih.gov/23976882/>23976882</a>
Effects of diet on resource utilization by a model human gut microbiota containing Bacteroides cellulosilyticus WH2, a symbiont with an extensive glycobiome. PLoS Biol. 2013;11(8):e1001637. doi: 10.1371/journal.pbio.1001637. Epub 2013 Aug 20.
2013 degradation 9 5 CBM13, CBM32, GH2, GH30_4, GH51_2
PUL0620 RNA-seq xylan Prevotella sp. PROD <a href=https://pubmed.ncbi.nlm.nih.gov/33113351/>33113351</a>
Distinct Polysaccharide Utilization Determines Interspecies Competition between Intestinal Prevotella spp. Cell Host Microbe. 2020 Dec 9;28(6):838-852.e6. doi: 10.1016/j.chom.2020.09.012. Epub 2020 Oct 27.
2020 Dec 9 degradation 10 2 GH128, GH51_2, GH43_19
PUL0624 RNA-seq xylan Prevotella sp. PMUR <a href=https://pubmed.ncbi.nlm.nih.gov/33113351/>33113351</a>
Distinct Polysaccharide Utilization Determines Interspecies Competition between Intestinal Prevotella spp. Cell Host Microbe. 2020 Dec 9;28(6):838-852.e6. doi: 10.1016/j.chom.2020.09.012. Epub 2020 Oct 27.
2020 Dec 9 degradation 11 3 GH128, GH43_24, GH51_2, GH43_19
PUL0648 high-performance anion-exchange chromatography, substrate binding assay, thin-layer chromatography, NMR, mass spectrometry, crystallization xylan Dysgonomonas mossii DSM 22836 <a href=https://pubmed.ncbi.nlm.nih.gov/33667545/>33667545</a>
A polysaccharide utilization locus from the gut bacterium Dysgonomonas mossii encodes functionally distinct carbohydrate esterases. J Biol Chem. 2021 Jan-Jun;296:100500. doi: 10.1016/j.jbc.2021.100500. Epub 2021 Mar 2.
2021 Jan-Jun degradation 37 21 CE1, CE1, CE1, CE20, CE20, CE6, GH10, GH115, GH146, GH31_4, GH43_1, GH43_10, CBM91, GH43_12, CBM91, GH43_29, GH43_29, CBM6, GH51_2, GH67, GH8, GH97
PUL0666 UHPLC-MS, RNA-seq, RT-qPCR pectin Bacteroides thetaiotaomicron VPI-5482 <a href=https://pubmed.ncbi.nlm.nih.gov/34420703/>34420703</a>
Discrete genetic loci in human gut Bacteroides thetaiotaomicron confer pectin metabolism. Carbohydr Polym. 2021 Nov 15;272:118534. doi: 10.1016/j.carbpol.2021.118534. Epub 2021 Aug 6.
2021 Nov 15 degradation 4 4 GH35, GH43_19, GH43_9, CBM91, GH43_19, GH51_2
PUL0716 growth assay, RT-PCR arabinan Mesoflavibacter profundi MTRN7 <a href=https://pubmed.ncbi.nlm.nih.gov/37550707/>37550707</a>
Deep-sea Bacteroidetes from the Mariana Trench specialize in hemicellulose and pectin degradation typically associated with terrestrial systems. Microbiome. 2023 Aug 7;11(1):175. doi: 10.1186/s40168-023-01618-7.
2023 Aug 7 degradation 16 8 GH127, GH43_26, GH43_29, GH43_4, GH43_5, GH51_1, GH51_2, GH97
PUL0735 enzyme activity assay, clone and expression, reducing-sugar assay, thin-layer chromatography, SDS-PAGE arabinan Bifidobacterium longum subsp. suis DSM 20211 <a href=https://pubmed.ncbi.nlm.nih.gov/38542148/>38542148</a>
Functional Characterization of Endo- and Exo-Hydrolase Genes in Arabinan Degradation Gene Cluster of Bifidobacterium longum subsp. suis. Int J Mol Sci. 2024 Mar 9;25(6):3175. doi: 10.3390/ijms25063175.
2024 Mar 9 degradation 17 7 GH127, GH27, GH43_26, GH43_27, GH43_4, GH51_2
PUL0769 RNA-seq, qRT-PCR, gas chromatography, mass spectrometry, thin-layer chromatography pectin Segatella copri DSM 18205 <a href=https://pubmed.ncbi.nlm.nih.gov/39636128/>39636128</a>
Transcriptional delineation of polysaccharide utilization loci in the human gut commensal Segatella copri DSM18205 and co-culture with exemplar Bacteroides species on dietary plant glycans. Appl Environ Microbiol. 2025 Jan 31;91(1):e0175924. doi: 10.1128/aem.01759-24. Epub 2024 Dec 5.
2025 Jan 31 degradation 9 3 GH43_4, GH43_5, GH51_2
PUL0794 enzyme activity assay, quantification of reaction product reducing ends, RNA-seq, differential gene expression, NMR, MALDI-TOF/MS, gas chromatography, mass spectrometry, bicinchoninic acid (BCA) assay, recombinant protein expression arabinan Bacteroides intestinalis DSM 17393 <a href=https://pubmed.ncbi.nlm.nih.gov/39443715/>39443715</a>
In vivo manipulation of human gut Bacteroides fitness by abiotic oligosaccharides. Nat Chem Biol. 2025 Apr;21(4):544-554. doi: 10.1038/s41589-024-01763-6. Epub 2024 Oct 23.
2025 Apr degradation 23 8 GH146, GH28, GH43_29, GH43_4, GH51_1, GH51_2, GH97