Browse dbCAN-PUL Entries

PULID Characterization Method(s) Substrate Organism Publication Publish Date Type Num Genes Num CAZymes CazyFamily
PUL0084 label-free quantitative proteomics, functional enrichment analysis, enzyme activity assay cellulose Ruminiclostridium papyrosolvens <a href=https://pubmed.ncbi.nlm.nih.gov/31338125/>31338125</a>
Secretomic analyses of Ruminiclostridium papyrosolvens reveal its enzymatic basis for lignocellulose degradation. Biotechnol Biofuels. 2019 Jul 15;12:183. doi: 10.1186/s13068-019-1522-8. eCollection 2019.
2019 degradation 12 12 CE1, CBM6, GH10, CBM6, GH27, CBM6, GH30_8, CBM6, GH43_10, CBM91, CBM6, GH43_29, CBM6, GH59, CBM6, GH62, CBM6, GH62, CBM6, CE6, GH95, CBM32
PUL0091 sequence homology analysis host glycan Phocaeicola vulgatus <a href=https://pubmed.ncbi.nlm.nih.gov/31275257/>31275257</a>
Investigating Host Microbiota Relationships Through Functional Metagenomics. Front Microbiol. 2019 Jun 7;10:1286. doi: 10.3389/fmicb.2019.01286. eCollection 2019.
2019 degradation 8 7 CE3, CE20, CE9, GH2, GH20, GH20, CBM32, GH92
PUL0092 sequence homology analysis host glycan Phocaeicola vulgatus <a href=https://pubmed.ncbi.nlm.nih.gov/31275257/>31275257</a>
Investigating Host Microbiota Relationships Through Functional Metagenomics. Front Microbiol. 2019 Jun 7;10:1286. doi: 10.3389/fmicb.2019.01286. eCollection 2019.
2019 degradation 10 5 CBM93, GH33, CE3, CE20, GH2, GH20, GH20, CBM32
PUL0106 fosmid library screen, lectin binding assay host glycan uncultured bacterium <a href=https://pubmed.ncbi.nlm.nih.gov/31275257/>31275257</a>
Investigating Host Microbiota Relationships Through Functional Metagenomics. Front Microbiol. 2019 Jun 7;10:1286. doi: 10.3389/fmicb.2019.01286. eCollection 2019.
2019 degradation 22 4 GH2, GH20, CBM32
PUL0112 fosmid library screen, lectin binding assay host glycan uncultured bacterium <a href=https://pubmed.ncbi.nlm.nih.gov/31275257/>31275257</a>
Investigating Host Microbiota Relationships Through Functional Metagenomics. Front Microbiol. 2019 Jun 7;10:1286. doi: 10.3389/fmicb.2019.01286. eCollection 2019.
2019 degradation 25 4 GH2, GH20, CBM32
PUL0114 recombinant protein expression, enzyme activity assay arabinan Ruminiclostridium cellulolyticum <a href=https://pubmed.ncbi.nlm.nih.gov/31198441/>31198441</a>
The xyl-doc gene cluster of Ruminiclostridium cellulolyticum encodes GH43- and GH62-alpha-l-arabinofuranosidases with complementary modes of action. Biotechnol Biofuels. 2019 Jun 10;12:144. doi: 10.1186/s13068-019-1483-y. eCollection 2019.
2019 degradation 14 14 CE1, CBM6, GH10, CBM6, GH146, CBM22, GH27, CBM6, GH2, CBM6, GH30_8, CBM6, GH43_10, CBM91, CBM6, GH43_16, CBM6, GH43_29, CBM6, GH59, CBM6, GH62, CBM6, GH62, CBM6, CE6, GH95, CBM32, CBM6
PUL0115 expression of recombinant proteins, RNA-seq, differential gene expression host glycan Bacteroides thetaiotaomicron <a href=https://pubmed.ncbi.nlm.nih.gov/31160824/>31160824</a>
Complex N-glycan breakdown by gut Bacteroides involves an extensive enzymatic apparatus encoded by multiple co-regulated genetic loci. Nat Microbiol. 2019 Sep;4(9):1571-1581. doi: 10.1038/s41564-019-0466-x. Epub 2019 Jun 3.
2019 Sep degradation 7 7 CBM93, GH33, CE3, CE20, GH2, GH20, GH20, CBM32
PUL0127 growth assay, sequence homology analysis alginate Alteromonas sp. 76-1 <a href=https://pubmed.ncbi.nlm.nih.gov/30936857/>30936857</a>
Adaptations of Alteromonas sp. 76-1 to Polysaccharide Degradation: A CAZyme Plasmid for Ulvan Degradation and Two Alginolytic Systems. Front Microbiol. 2019 Mar 18;10:504. doi: 10.3389/fmicb.2019.00504. eCollection 2019.
2019 degradation 12 4 CBM32, PL7_5, PL6_3, PL6, PL6_1, PL7_5
PUL0160 mass spectrometry, sequence homology analysis alpha-mannan Salegentibacter sp. Hel_I_6 <a href=https://pubmed.ncbi.nlm.nih.gov/30246424/>30246424</a>
Alpha- and beta-mannan utilization by marine Bacteroidetes. Environ Microbiol. 2018 Nov;20(11):4127-4140. doi: 10.1111/1462-2920.14414. Epub 2018 Oct 16.
2018 Nov degradation 35 12 AA3, CBM32, GH125, GH2, GH43_34, GH76, GH92
PUL0163 mass spectrometry, sequence homology analysis, microarray, qPCR alpha-mannan Bacteroides thetaiotaomicron <a href=https://pubmed.ncbi.nlm.nih.gov/30246424/>30246424</a>, <a href=https://pubmed.ncbi.nlm.nih.gov/18996345/>18996345</a>
Alpha- and beta-mannan utilization by marine Bacteroidetes. Mucosal glycan foraging enhances fitness and transmission of a saccharolytic human gut bacterial symbiont. Environ Microbiol. 2018 Nov;20(11):4127-4140. doi: 10.1111/1462-2920.14414. Epub 2018 Oct 16. Cell Host Microbe. 2008 Nov 13;4(5):447-57. doi: 10.1016/j.chom.2008.09.007.
2018 Nov,2008 Nov 13 degradation 21 9 GH125, GH130_3, GH38, CBM32, GH76, GH92, GT32
PUL0192 RNA-seq, RT-PCR, qPCR pectin Bacteroides xylanisolvens <a href=https://pubmed.ncbi.nlm.nih.gov/26920945/>26920945</a>
Unraveling the pectinolytic function of Bacteroides xylanisolvens using a RNA-seq approach and mutagenesis. BMC Genomics. 2016 Feb 27;17:147. doi: 10.1186/s12864-016-2472-1.
2016 Feb 27 degradation 27 14 CE12, CE12, CE12, GH105, GH106, GH2, GH28, GH42, GH43_18, GH43_34, CBM32, PL11, PL11_1, PL26
PUL0199 enzyme activity assay, liquid chromatography and mass spectrometry alginate Saccharophagus degradans <a href=https://pubmed.ncbi.nlm.nih.gov/26458373/>26458373</a>
Putative Alginate Assimilation Process of the Marine Bacterium Saccharophagus degradans 2-40 Based on Quantitative Proteomic Analysis. Mar Biotechnol (NY). 2016 Feb;18(1):15-23. doi: 10.1007/s10126-015-9667-3. Epub 2015 Oct 12.
2016 Feb degradation 17 6 CBM16, CBM32, PL18, PL17_2, PL17, PL6, PL6, PL6_1, PL7_5
PUL0224 RT-PCR, qRT-PCR, ion trap liquid chromatography, mass spectrometry, target decoy database analysis, high-performance anion-exchange chromatography cellulose Ruminiclostridium cellulolyticum <a href=https://pubmed.ncbi.nlm.nih.gov/23418511/>23418511</a>, <a href=https://pubmed.ncbi.nlm.nih.gov/20013800/>20013800</a>
A two-component system (XydS/R) controls the expression of genes encoding CBM6-containing proteins in response to straw in Clostridium cellulolyticum. Modulation of cellulosome composition in Clostridium cellulolyticum: adaptation to the polysaccharide environment revealed by proteomic and carbohydrate-active enzyme analyses. PLoS One. 2013;8(2):e56063. doi: 10.1371/journal.pone.0056063. Epub 2013 Feb 13. Proteomics. 2010 Feb;10(3):541-54. doi: 10.1002/pmic.200900311.
2013,2010 Feb degradation 16 14 CE1, CBM6, GH10, CBM6, GH146, CBM22, GH27, CBM6, GH2, CBM6, GH30_8, CBM6, GH43_10, CBM91, CBM6, GH43_16, CBM6, GH43_29, CBM6, GH59, CBM6, GH62, CBM6, GH62, CBM6, CE6, GH95, CBM32, CBM6
PUL0251 gene chips host glycan Bacteroides thetaiotaomicron <a href=https://pubmed.ncbi.nlm.nih.gov/23996813/>23996813</a>
Regulated expression of polysaccharide utilization and capsular biosynthesis loci in biofilm and planktonic Bacteroides thetaiotaomicron during growth in chemostats. Biotechnol Bioeng. 2014 Jan;111(1):165-73. doi: 10.1002/bit.24994. Epub 2013 Jul 30.
2014 Jan degradation 7 1 CBM32
PUL0252 gene chips mucin Bacteroides thetaiotaomicron <a href=https://pubmed.ncbi.nlm.nih.gov/23996813/>23996813</a>
Regulated expression of polysaccharide utilization and capsular biosynthesis loci in biofilm and planktonic Bacteroides thetaiotaomicron during growth in chemostats. Biotechnol Bioeng. 2014 Jan;111(1):165-73. doi: 10.1002/bit.24994. Epub 2013 Jul 30.
2014 Jan degradation 6 2 CBM32, GH29, CBM32
PUL0348 enzyme activity assay host glycan Bacteroides fragilis <a href=https://pubmed.ncbi.nlm.nih.gov/22449996/>22449996</a>
Characterization of a gene cluster for sialoglycoconjugate utilization in Bacteroides fragilis. J Med Invest. 2012;59(1-2):79-94. doi: 10.2152/jmi.59.79.
2012 degradation 13 9 CBM93, GH33, CE3, CE20, GH2, GH20, GH20, CBM32, GH92
PUL0357 microarray host glycan Bacteroides thetaiotaomicron <a href=https://pubmed.ncbi.nlm.nih.gov/16968696/>16968696</a>
Functional genomic and metabolic studies of the adaptations of a prominent adult human gut symbiont, Bacteroides thetaiotaomicron, to the suckling period. J Biol Chem. 2006 Nov 24;281(47):36269-79. doi: 10.1074/jbc.M606509200. Epub 2006 Sep 12.
2006 Nov 24 degradation 3 1 CBM32
PUL0382 microarray, qPCR mucin Bacteroides thetaiotaomicron <a href=https://pubmed.ncbi.nlm.nih.gov/18996345/>18996345</a>
Mucosal glycan foraging enhances fitness and transmission of a saccharolytic human gut bacterial symbiont. Cell Host Microbe. 2008 Nov 13;4(5):447-57. doi: 10.1016/j.chom.2008.09.007.
2008 Nov 13 degradation 11 4 CBM32, GH109, GH2
PUL0398 gene deletion mutant and growth assay mucin Capnocytophaga canimorsus <a href=https://pubmed.ncbi.nlm.nih.gov/21762219/>21762219</a>, <a href=https://pubmed.ncbi.nlm.nih.gov/25736888/>25736888</a>
The genome and surface proteome of Capnocytophaga canimorsus reveal a key role of glycan foraging systems in host glycoproteins deglycosylation. Glycan-foraging systems reveal the adaptation of Capnocytophaga canimorsus to the dog mouth. Mol Microbiol. 2011 Aug;81(4):1050-60. doi: 10.1111/j.1365-2958.2011.07750.x. Epub 2011 Jul 18. mBio. 2015 Mar 3;6(2):e02507. doi: 10.1128/mBio.02507-14.
2011 Aug,2015 Mar 3 degradation 9 3 CBM32, GH2
PUL0400 RT-qPCR, RNA-seq alginate Alteromonas macleodii <a href=https://pubmed.ncbi.nlm.nih.gov/25847866/>25847866</a>, <a href=https://pubmed.ncbi.nlm.nih.gov/30116038/>30116038</a>
Different utilization of alginate and other algal polysaccharides by marine Alteromonas macleodii ecotypes. Biphasic cellular adaptations and ecological implications of Alteromonas macleodii degrading a mixture of algal polysaccharides. Environ Microbiol. 2015 Oct;17(10):3857-68. doi: 10.1111/1462-2920.12862. Epub 2015 May 8. ISME J. 2019 Jan;13(1):92-103. doi: 10.1038/s41396-018-0252-4. Epub 2018 Aug 16.
2015 Oct,2019 Jan degradation 14 5 CBM32, PL7_5, PL17_2, PL17, PL6_3, PL6, PL6_1, PL7_5
PUL0415 microarray xylan Bacteroides ovatus <a href=https://pubmed.ncbi.nlm.nih.gov/22205877/>22205877</a>
Recognition and degradation of plant cell wall polysaccharides by two human gut symbionts. PLoS Biol. 2011 Dec;9(12):e1001221. doi: 10.1371/journal.pbio.1001221. Epub 2011 Dec 20.
2011 Dec degradation 4 2 GH20, GH20, CBM32
PUL0436 mass spectrometry, high-performance anion-exchange chromatography glucomannan Chitinophaga pinensis <a href=https://pubmed.ncbi.nlm.nih.gov/28069559/>28069559</a>
Proteomic insights into mannan degradation and protein secretion by the forest floor bacterium Chitinophaga pinensis. J Proteomics. 2017 Mar 6;156:63-74. doi: 10.1016/j.jprot.2017.01.003. Epub 2017 Jan 6.
2017 Mar 6 degradation 8 3 CBM32, CBM32, GH13_46, GH65
PUL0443 mass spectrometry, high-performance anion-exchange chromatography glucomannan Chitinophaga pinensis <a href=https://pubmed.ncbi.nlm.nih.gov/28069559/>28069559</a>
Proteomic insights into mannan degradation and protein secretion by the forest floor bacterium Chitinophaga pinensis. J Proteomics. 2017 Mar 6;156:63-74. doi: 10.1016/j.jprot.2017.01.003. Epub 2017 Jan 6.
2017 Mar 6 degradation 9 3 CBM6, CBM6, GH16_3, CBM32, GH16_3, CBM92
PUL0464 microarray, qPCR host glycan Bacteroides thetaiotaomicron <a href=https://pubmed.ncbi.nlm.nih.gov/18996345/>18996345</a>
Mucosal glycan foraging enhances fitness and transmission of a saccharolytic human gut bacterial symbiont. Cell Host Microbe. 2008 Nov 13;4(5):447-57. doi: 10.1016/j.chom.2008.09.007.
2008 Nov 13 degradation 16 8 CBM93, GH33, CE20, GH2, GH20, GH20, CBM32
PUL0467 microarray, qPCR, expression of recombinant proteins, RNA-seq, differential gene expression host glycan Bacteroides thetaiotaomicron <a href=https://pubmed.ncbi.nlm.nih.gov/18996345/>18996345</a>, <a href=https://pubmed.ncbi.nlm.nih.gov/31160824/>31160824</a>
Mucosal glycan foraging enhances fitness and transmission of a saccharolytic human gut bacterial symbiont. Complex N-glycan breakdown by gut Bacteroides involves an extensive enzymatic apparatus encoded by multiple co-regulated genetic loci. Cell Host Microbe. 2008 Nov 13;4(5):447-57. doi: 10.1016/j.chom.2008.09.007. Nat Microbiol. 2019 Sep;4(9):1571-1581. doi: 10.1038/s41564-019-0466-x. Epub 2019 Jun 3.
2008 Nov 13,2019 Sep degradation 14 4 GH18, GH2, GH20, GH29, CBM32
PUL0471 microarray, qPCR mucin Bacteroides thetaiotaomicron <a href=https://pubmed.ncbi.nlm.nih.gov/18996345/>18996345</a>
Mucosal glycan foraging enhances fitness and transmission of a saccharolytic human gut bacterial symbiont. Cell Host Microbe. 2008 Nov 13;4(5):447-57. doi: 10.1016/j.chom.2008.09.007.
2008 Nov 13 degradation 9 4 CBM32, GH92
PUL0476 growth assay pectin Flavobacterium johnsoniae <a href=https://pubmed.ncbi.nlm.nih.gov/19717629/>19717629</a>
Novel features of the polysaccharide-digesting gliding bacterium Flavobacterium johnsoniae as revealed by genome sequence analysis. Appl Environ Microbiol. 2009 Nov;75(21):6864-75. doi: 10.1128/AEM.01495-09. Epub 2009 Aug 28.
2009 Nov degradation 11 6 GH2, GH29, CBM32, CBM32, GH43_18, GH43_26, GH43_31, GH5_13
PUL0535 RNA-seq arabinogalactan Bacteroides cellulosilyticus <a href=https://pubmed.ncbi.nlm.nih.gov/23976882/>23976882</a>
Effects of diet on resource utilization by a model human gut microbiota containing Bacteroides cellulosilyticus WH2, a symbiont with an extensive glycobiome. PLoS Biol. 2013;11(8):e1001637. doi: 10.1371/journal.pbio.1001637. Epub 2013 Aug 20.
2013 degradation 9 3 CBM32, GH16_3, GH43_24, GH16_3
PUL0546 RNA-seq arabinogalactan Bacteroides cellulosilyticus <a href=https://pubmed.ncbi.nlm.nih.gov/23976882/>23976882</a>
Effects of diet on resource utilization by a model human gut microbiota containing Bacteroides cellulosilyticus WH2, a symbiont with an extensive glycobiome. PLoS Biol. 2013;11(8):e1001637. doi: 10.1371/journal.pbio.1001637. Epub 2013 Aug 20.
2013 degradation 9 5 CBM13, CBM32, GH2, GH30_4, GH51_2
PUL0559 gene deletion mutant and growth assay, growth assay, enzyme activity assay, microarray, qPCR pectin Bacteroides thetaiotaomicron <a href=https://pubmed.ncbi.nlm.nih.gov/28329766/>28329766</a>, <a href=https://pubmed.ncbi.nlm.nih.gov/18996345/>18996345</a>, <a href=https://pubmed.ncbi.nlm.nih.gov/22205877/>22205877</a>, <a href=https://pubmed.ncbi.nlm.nih.gov/16968696/>16968696</a>
Complex pectin metabolism by gut bacteria reveals novel catalytic functions. Mucosal glycan foraging enhances fitness and transmission of a saccharolytic human gut bacterial symbiont. Recognition and degradation of plant cell wall polysaccharides by two human gut symbionts. Functional genomic and metabolic studies of the adaptations of a prominent adult human gut symbiont, Bacteroides thetaiotaomicron, to the suckling period. Nature. 2017 Apr 6;544(7648):65-70. doi: 10.1038/nature21725. Epub 2017 Mar 22. Cell Host Microbe. 2008 Nov 13;4(5):447-57. doi: 10.1016/j.chom.2008.09.007. PLoS Biol. 2011 Dec;9(12):e1001221. doi: 10.1371/journal.pbio.1001221. Epub 2011 Dec 20. J Biol Chem. 2006 Nov 24;281(47):36269-79. doi: 10.1074/jbc.M606509200. Epub 2006 Sep 12.
2017 Apr 6,2008 Nov 13,2011 Dec,2006 Nov 24 degradation 12 4 GH29, GH43_10, CBM91, GH43_34, CBM32, GH97
PUL0609 enzyme activity assay, clone and expression, liquid chromatography and mass spectrometry, thin-layer chromatography, MALDI-TOF/MS human milk oligosaccharide Roseburia inulinivorans DSM 16841 <a href=https://pubmed.ncbi.nlm.nih.gov/32620774/>32620774</a>
Butyrate producing colonic Clostridiales metabolise human milk oligosaccharides and cross feed on mucin via conserved pathways. Nat Commun. 2020 Jul 3;11(1):3285. doi: 10.1038/s41467-020-17075-x.
2020 Jul 3 degradation 11 4 GH112, GH136, CBM32, GH95
PUL0689 clone and expression, crystallization, recombinant protein expression, thin-layer chromatography galactooligosaccharide Bacteroides thetaiotaomicron VPI-5482 <a href=https://pubmed.ncbi.nlm.nih.gov/34149636/>34149636</a>, <a href=https://pubmed.ncbi.nlm.nih.gov/37598339/>37598339</a>
Analysis of Two SusE-Like Enzymes From Bacteroides thetaiotaomicron Reveals a Potential Degradative Capacity for This Protein Family. Dynamic genetic adaptation of Bacteroides thetaiotaomicron during murine gut colonization. Front Microbiol. 2021 Jun 4;12:645765. doi: 10.3389/fmicb.2021.645765. eCollection 2021. Cell Rep. 2023 Aug 29;42(8):113009. doi: 10.1016/j.celrep.2023.113009. Epub 2023 Aug 21.
2021,2023 Aug 29 degradation 10 4 GH2, CBM32, GH3, GH36, GH43_10, CBM91
PUL0691 recombinant protein expression, qRT-PCR alginate Vibrio pelagius WXL662 <a href=https://pubmed.ncbi.nlm.nih.gov/36409133/>36409133</a>
Characterization of Multiple Alginate Lyases in a Highly Efficient Alginate-Degrading Vibrio Strain and Its Degradation Strategy. Appl Environ Microbiol. 2022 Dec 13;88(23):e0138922. doi: 10.1128/aem.01389-22. Epub 2022 Nov 21.
2022 Dec 13 degradation 12 2 CBM32, PL7_5, PL7, PL7
PUL0723 crystallization, high-performance anion-exchange chromatography, enzyme activity assay pectin Phocaeicola dorei DSM 17855 <a href=https://pubmed.ncbi.nlm.nih.gov/38179933/>38179933</a>
Polysaccharide utilization loci from Bacteroidota encode CE15 enzymes with possible roles in cleaving pectin-lignin bonds. Appl Environ Microbiol. 2024 Jan 24;90(1):e0176823. doi: 10.1128/aem.01768-23. Epub 2024 Jan 5.
2024 Jan 24 degradation 17 12 CE12, CE15, GH105, GH106, GH106, GH28, GH2, GH28, GH42, GH43_18, GH43_34, CBM32, GH78, PL11
PUL0724 crystallization, high-performance anion-exchange chromatography, enzyme activity assay pectin Phocaeicola vulgatus ATCC 8482 <a href=https://pubmed.ncbi.nlm.nih.gov/38179933/>38179933</a>
Polysaccharide utilization loci from Bacteroidota encode CE15 enzymes with possible roles in cleaving pectin-lignin bonds. Appl Environ Microbiol. 2024 Jan 24;90(1):e0176823. doi: 10.1128/aem.01768-23. Epub 2024 Jan 5.
2024 Jan 24 degradation 16 12 CE12, CE15, GH105, GH106, GH106, GH28, GH2, GH28, GH42, GH43_18, GH43_34, CBM32, GH78, PL11
PUL0728 HPAEC-PAD, SDS-PAGE, clone and expression human milk oligosaccharide Akkermansia muciniphila CSUN-19 <a href=https://pubmed.ncbi.nlm.nih.gov/38299857/>38299857</a>
Mechanism of 2'-fucosyllactose degradation by human-associated Akkermansia. J Bacteriol. 2024 Feb 22;206(2):e0033423. doi: 10.1128/jb.00334-23. Epub 2024 Feb 1.
2024 Feb 22 degradation 18 5 CBM50, GH27, GH29, GH2, CBM32, GH33
PUL0746 high performance gel permeation chromatography, gas chromatography, RNA-seq, differential gene expression pectic polysaccharide Bacteroides ovatus strain ATCC 8483 <a href=https://pubmed.ncbi.nlm.nih.gov/38890895/>38890895</a>
The Utilization by Bacteroides spp. of a Purified Polysaccharide from Fuzhuan Brick Tea. Foods. 2024 May 26;13(11):1666. doi: 10.3390/foods13111666.
2024 May 26 degradation 7 4 CBM93, GH33, GH2, GH20, GH20, CBM32
PUL0747 high performance gel permeation chromatography, gas chromatography, RNA-seq, differential gene expression pectic polysaccharide Bacteroides ovatus strain ATCC 8483 <a href=https://pubmed.ncbi.nlm.nih.gov/38890895/>38890895</a>
The Utilization by Bacteroides spp. of a Purified Polysaccharide from Fuzhuan Brick Tea. Foods. 2024 May 26;13(11):1666. doi: 10.3390/foods13111666.
2024 May 26 degradation 9 3 GH2, GH20, GH29, CBM32
PUL0756 RNA-seq, qRT-PCR N-glycan Barnesiella intestinihominis <a href=https://pubmed.ncbi.nlm.nih.gov/39510934/>39510934</a>
Molecular mechanisms of complex-type N-glycan breakdown and metabolism by the human intestinal bacterium Barnesiella intestinihominis. J Biosci Bioeng. 2025 Jan;139(1):14-22. doi: 10.1016/j.jbiosc.2024.10.006. Epub 2024 Nov 7.
2025 Jan degradation 11 7 GH130_2, GH20, GH84, CBM32, GH85, GH92
PUL0780 RNA-seq, differential gene expression, HPAEC-PAD, SDS-PAGE, para-hydroxybenzoic acid (PAHBAH) assay, reducing-sugar assay, Carbohydrate Polyacrylamide Gel Electrophoresis (C-PAGE), enzyme activity assay fucoidan Neorhodopirellula lusitana <a href=https://pubmed.ncbi.nlm.nih.gov/39738071/>39738071</a>
Mechanisms of recalcitrant fucoidan breakdown in marine Planctomycetota. Nat Commun. 2024 Dec 30;15(1):10906. doi: 10.1038/s41467-024-55268-w.
2024 Dec 30 degradation 24 8 CBM32, CE12, CE6, GH141, GH29, GH95
PUL0793 enzyme activity assay, quantification of reaction product reducing ends, RNA-seq, differential gene expression, NMR, MALDI-TOF/MS, gas chromatography, mass spectrometry, bicinchoninic acid (BCA) assay, recombinant protein expression arabinan Bacteroides intestinalis DSM 17393 <a href=https://pubmed.ncbi.nlm.nih.gov/39443715/>39443715</a>
In vivo manipulation of human gut Bacteroides fitness by abiotic oligosaccharides. Nat Chem Biol. 2025 Apr;21(4):544-554. doi: 10.1038/s41589-024-01763-6. Epub 2024 Oct 23.
2025 Apr degradation 14 6 CE1, GH127, GH146, GH43_34, CBM32, GH97