LOCUS       NZ_CP102288             9715 bp    DNA     linear   CON 29-JUL-2024
DEFINITION  Segatella copri DSM 18205 chromosome, complete genome.
ACCESSION   NZ_CP102288 REGION: 355831..365545
VERSION     NZ_CP102288.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN20222705
            Assembly: GCF_025151535.1
KEYWORDS    RefSeq.
SOURCE      Segatella copri DSM 18205
  ORGANISM  Segatella copri DSM 18205
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Prevotellaceae; Segatella.
REFERENCE   1  (bases 1 to 9715)
  AUTHORS   Cheng,A.G., Ho,P.Y., Aranda-Diaz,A., Jain,S., Yu,F.B., Meng,X.,
            Wang,M., Iakiviak,M., Nagashima,K., Zhao,A., Murugkar,P., Patil,A.,
            Atabakhsh,K., Weakley,A., Yan,J., Brumbaugh,A.R., Higginbottom,S.,
            Dimas,A., Shiver,A.L., Deutschbauer,A., Neff,N., Sonnenburg,J.L.,
            Huang,K.C. and Fischbach,M.A.
  TITLE     Design, construction, and in vivo augmentation of a complex gut
            microbiome
  JOURNAL   Cell 185 (19), 3617-3636 (2022)
   PUBMED   36070752
REFERENCE   2  (bases 1 to 9715)
  AUTHORS   Cheng,A.G., Jain,S., Meng,X. and Fischbach,M.A.
  TITLE     Direct Submission
  JOURNAL   Submitted (29-JUL-2022) Chem-H, Stanford University, 290 Jane
            Stanford Way, Stanford, CA 94305, USA
COMMENT     REFSEQ INFORMATION: The reference sequence is identical to
            CP102288.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 2021
            Assembly Method        :: Unicycler v. 0.4.8
            Assembly Name          :: Prevotella-copri-DSM-18205-MAF-2
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: 100x
            Sequencing Technology  :: Illumina HiSeq; Oxford Nanopore
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_025151535.1-RS_2024_07_29
            Annotation Date                   :: 07/29/2024 03:59:40
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,796
            CDSs (total)                      :: 2,718
            Genes (coding)                    :: 2,663
            CDSs (with protein)               :: 2,663
            Genes (RNA)                       :: 78
            rRNAs                             :: 5, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 5, 5, 5 (5S, 16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 13 of 55
            Pseudo Genes (incomplete)         :: 44 of 55
            Pseudo Genes (internal stop)      :: 9 of 55
            Pseudo Genes (multiple problems)  :: 11 of 55
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..9715
                     /organism="Segatella copri DSM 18205"
                     /mol_type="genomic DNA"
                     /strain="DSM 18205"
                     /host="Homo sapiens"
                     /culture_collection="DSM:18205"
                     /type_material="type strain of Prevotella copri"
                     /db_xref="taxon:537011"
     gene            1..4137
                     /locus_tag="NQ544_RS01410"
                     /old_locus_tag="NQ544_01410"
     CDS             1..4137
                     /locus_tag="NQ544_RS01410"
                     /old_locus_tag="NQ544_01410"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: protein motif:HMM:NF014567.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hybrid sensor histidine kinase/response
                     regulator transcription factor"
                     /protein_id="WP_006847717.1"
                     /translation="MMIKKQNYLKHAIVLFLLLLLMQPERAWAAYENVEFSSLTNHDG
                     LTNSQVGAILKDTRGYIWFGTQSGLCRFDGFRMKTFYYSNTDDKSLPNNSVDELQQDY
                     DGNIWVHTSVGYSIYKYDEEQFERKPEEWLKNIHVQGPPYKLLIDKDKNMWIAVYGQG
                     LFFHNAKTKNTYLFKFTKKAQPGCLKEGNISKITEVDGDALITYGDGTICRVNGQKQK
                     VLWYNSFLATHKAAGDNGAYTFYDGIGGFWVSVSSANYVYQSKTGKWTDARSYLENMG
                     IHIPCPTRILMRDIARDKAGNLWVASDHNGLFFVDFKRKICRQYVHSEAKGSIIDNSL
                     QKVYVDDEGAIWVGSYKNGVAYYSPAAQKFTTIPLGDVCTITQDLNGNLWCGTNDSGI
                     VCYSPLTGQSRRFSQAETGLASDIIVSSVTMSDGTMYFGTFNGGLAQYKNGRWKSFQA
                     APGGLANNSVWCLAEDPYHRLIIGTLGSGFQIYNPESGKFTTYNVQNSGITSDFINSL
                     FLPNKDEILIGHSQNYSIFNFGTRKVTNVNTTKDGQPFPSPSLNYMMKDSRGILWIAS
                     PAGVTMYDEASGQLESINDLNGTQGTVGCMVLEDKQHNIWLVSEFIVTRVTLTKNNQG
                     KWDITMISFNSLDGLQSRQFNQRSACLMRNGAIAIGGQDGINIINPAKILPAQKHAHV
                     LFSGFVLFDHPLKAGEEFEGRVPLEKSLDTHPELDLSYKDKAFTIQFASDQVSIPARC
                     RFLYRMKGLDDKWMLTPEGRPEATFTNLSSGSYVLEAKVVNADGSVSEEVSTLKIYIH
                     PPFYLSIWAFIVYIILIGVAFYLYRKRMLEKQRVKFELQSKEDSIKKTKELNELKLNF
                     FTNVSHELRTPLTLIISPLVNMIREERDESKRRKLEMIHRNATRLLNLVNQILDFRKI
                     DQNKEKLTLSHIDIVSFVDNICTSFRTLANSKVTLAFYSTVPSLQMSFDADKVGKIVN
                     NLLSNAYKFTPDGGFITVSLSVALHQRVGDKDSDMLRISVSDTGKGISDKEKEHVFER
                     FYQVNGTEMQPQGGSGIGLNLVKKFAELHGGKVDVTDNPSGGTIFMVDLPIESSTTSN
                     STAHLGSLRAAPIITTVHQATDEDPDAGKNVLYGMSKHAHQPGESMIKKPVVLLVDDS
                     EDFREFMNEVLTDYTVVEAVNGQDAWNKIIDRRPDLILSDVMMPVMDGNELCRMCKDN
                     DETTAIPFIMLSARMGDEQRKESLKCGADEYIAKPFDIDMLNLCILNLLKKRKNVSTE
                     YVITEADRKFIDEVNAYIRDHMSNPETSVESLSTHLCISRVQLYKRMISLTGITPSEY
                     LRTKRIKFAEHLLRSGDLNISEIAYKVGFNNPRYFTKYFQDTYGVTPSQYRKNLSESE
                     "
     gene            4252..7206
                     /locus_tag="NQ544_RS01415"
                     /old_locus_tag="NQ544_01415"
     CDS             4252..7206
                     /locus_tag="NQ544_RS01415"
                     /old_locus_tag="NQ544_01415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007410922.1"
                     /GO_function="GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIM-barrel domain-containing protein"
                     /protein_id="WP_006847716.1"
                     /translation="MRLTKTLLISAVLLMSATGMQAAGFNQNGNYLTVQLKQHQNFGP
                     SQIRLQVVSDKIIRVQATAEQSFRNKQSLIIVPQNSKANYKVEEQGDNLIITTAAMRA
                     VMNEATGQITFYDLKDNVLLNEVAQGGKTFKPFTVPDREIGVDIAKVPEAQKHGWSWR
                     ALFNSPDNEAFYGLGQHQSEELNMKGKNEDLFQYNTKVSVPFVISNKNYGILWDSYSY
                     CRWGNPEDYLQLNRAFKLYDKDGKEGQLTGTYVDKNGQKIVRGEDSIYFEYAMPETSE
                     ICNKTDKGGIQNLPKGFALNGSKVVYEGYVEAPSNSFYQFILYYAGYMKIYINGKLVV
                     PERWRTAWNPNSYKFETPIKKGVKTPIRIEWQPDGDVSYCGLRVAAPRSEAEKNQLSI
                     WSEMSPDMDYYFIAGQNLDEVISGYRTLTGKASLYPKWTLGFWQSRERYQSSKDIKDN
                     MKKFRDLHIPVDNIVQDWNYWKLDSWGSHEFEAARYPNPQAMLDSVHAMNGRFMISVW
                     PKFYDTVKNYKELDSKGWMYHQAIKDDIHDWLGFRGSFYDAYSDGARKMFWRQMDENL
                     YTKYKFGIDAWWMDASEPNVRDCTPMWYRKALSGPTALGTSTEYFNAYSIVNADAIYN
                     GQRSVNPNQRVFLLTRSGFAGEQRYSTATWSGDIATRWEDMRAQMTAGLNYSMAGLPF
                     WGMDQGGFCVENRYVAAQQEFDKTGKENADLKEWRELQARWNQFGCFVPLYRTHGQWP
                     TREVWNIAPADHPAYKTIVAYDKLRYRLMPYLYSMAGMVHFKDYTMMRGLVMDFNGDD
                     NVYDIKDQWMFGPALMACPVGEYQKYSRNVYLPKQKGWYDFYTGKHYAGGQTIVADAP
                     FDKIPVFVPEGSILPVGPEMEWSNQKKAELIDLYVYAGKDGSYTLYEDEGTNYNYEKG
                     KYAMIDFKYNDAQKTITIAARKGSFDGMLQKRRFNIVLVSDNNQQGISLAKAPKGKMV
                     KYAGKAVTVKLK"
     gene            7208..9715
                     /locus_tag="NQ544_RS01420"
                     /old_locus_tag="NQ544_01420"
     CDS             7208..9715
                     /locus_tag="NQ544_RS01420"
                     /old_locus_tag="NQ544_01420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019967870.1"
                     /GO_function="GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 2 TIM barrel-domain
                     containing protein"
                     /protein_id="WP_006847715.1"
                     /translation="MKKIFALAIFLLGAQSLSARDRQSFDKGWLFTLADSAGMSKSDY
                     SDRHWRSLNLPHDWAIEGDFSPSNPSGAGGGALPGGIGWYRKHFSVNPKEKYDRFTIT
                     FDGVYMNSTVYINGHKLGTRPYGYSTFEYDLTPYINKKGDNVIAVKVDNSDQPNSRWY
                     SGCGIYRHVWLTKTMKSAYIPQWGQYVATSPQGDVRVKVDFAASGNKMKLSVRNTIYD
                     AAGKIVAKSQGVREQKFKVKNPHLWDIGKGYLYTVKSELLVNGKVVDVATSTAGFRDV
                     KFDAKKGFFLNGKNLKINGVCEHHDFGCLGAAVNEDAMHRKLTILRDMGVNAIRSSHN
                     PPAPELLNMCDSMGFLVMDESFDMWRRKKSNGDYARFFDEWHKKDLSDLIKRDRNHPS
                     IIMWSIGNEVLEQWSDVAADTLSLEQANLILNAGHDASSLSHSNELSVNSLLTQHLAK
                     IVKEYDPWGTRPVTAGCNEPDPKNHLFKSGAIDVIGFNYHHQWVKDVPKNFPGKPFIL
                     SESVSALQTRGYYMMPSDSIYTAPKEWWLPYTDPLFMCSAYDNFHASWSSTHEETWDV
                     VKHNDFVGGQFIWTGFDYIGEPTPYAYPARSSYFGIIDLAGLPKDSYYMYQSEWTQKD
                     VLHLFPHWNWLPGQTIDMWCYYNHADEVELFINGKSQGIRKKTVYGAKNEGDAFRKST
                     EYHVMWRVNFEPGEVKVVARKNGKVLREQVIKTAGAPHHLVLKKTYQGCQAFGSSDPT
                     TFVEVNVVDKDGNLCPNADNQIFFSVSGEQDASGHGFLKTPKILGTDNGCQTSLERFT
                     DSHRKAFFGKCVVVIKGKGTLKAQAVDLKDASVALWL"
ORIGIN      
        1 atgatgataa aaaaacaaaa ctacttgaaa catgccatcg tgctgtttct gctcttgctg
       61 ctcatgcagc cggagagggc atgggctgcc tatgaaaacg tagaattcag cagcctcacc
      121 aatcatgatg gacttactaa cagtcaggtg ggtgccattc tcaaggacac cagaggctac
      181 atctggttcg gtacccagtc gggactgtgc cgctttgacg gcttccgtat gaaaactttc
      241 tattatagca acactgatga taagtcgctg cctaacaatt cggtagatga acttcagcaa
      301 gactatgatg gaaatatctg ggtgcatacc tctgtgggtt acagcatcta caaatatgat
      361 gaagagcagt ttgagcgcaa accggaagaa tggctcaaaa acatccatgt gcagggacct
      421 ccttacaaac tcctgataga taaggataag aacatgtgga tagctgtcta cggacaggga
      481 ctcttctttc ataatgccaa gaccaaaaat acttatcttt ttaaatttac caaaaaggct
      541 cagccgggct gtctgaaaga gggaaatatc agtaaaataa ccgaggttga cggcgatgcg
      601 ctcattacct atggtgatgg tacaatctgc cgtgtcaacg gacagaaaca gaaggttctc
      661 tggtacaatt ccttccttgc cacccataaa gctgccggtg ataatggtgc ctatactttc
      721 tatgatggta taggtggttt ctgggtttca gtaagtagtg ccaattacgt gtatcagtca
      781 aagaccggga aatggaccga tgcccgttct tatcttgaga acatgggcat tcatattcct
      841 tgcccaaccc gtattctgat gcgtgatatt gcccgcgata aggcaggcaa tctctgggtg
      901 gcttccgacc ataacggtct cttctttgtt gatttcaaac gcaaaatctg ccgtcagtat
      961 gttcattccg aagcaaaggg aagtatcatt gacaattccc tgcagaaggt ttatgtggat
     1021 gatgagggag ctatctgggt aggtagttac aagaacggcg tggcttatta ttcgcctgct
     1081 gctcagaaat tcacaactat tccgcttggt gatgtgtgca caatcacaca ggatctgaat
     1141 ggaaatctct ggtgcggaac caatgatagc ggtattgtat gctacagtcc gcttaccgga
     1201 cagagtcggc gattctcaca ggctgaaact ggtttggctt cggatattat cgtcagcagc
     1261 gtaaccatga gtgatggtac gatgtatttc ggtaccttca atggtggact tgcccaatat
     1321 aaaaacggca gatggaagag ttttcaggca gctcctggcg gacttgccaa taatagcgtc
     1381 tggtgtcttg ccgaagatcc gtatcatcgc ctgattatcg gaaccttggg ctcaggcttc
     1441 cagatttata atcctgaaag tggtaagttt acaacctaca atgttcagaa ttcaggtatt
     1501 accagcgatt ttatcaactc gctcttcctg ccgaataaag atgaaattct gataggtcat
     1561 tcgcagaact attctatctt taatttcgga acccgaaagg taaccaatgt gaatacaacc
     1621 aaggacggac agcctttccc tagtccttcc ctgaattaca tgatgaagga tagccgaggc
     1681 atcttgtgga tagcttcgcc tgcgggcgtc accatgtatg atgaggcttc aggacagttg
     1741 gagtcaatca atgacctcaa tggtacgcag ggcacggtag gctgtatggt gctcgaagat
     1801 aagcagcata acatctggct ggtttctgaa tttatcgtta cccgtgttac gctgaccaag
     1861 aacaaccagg gcaaatggga cattacgatg atcagcttca attcgctcga tggcttgcag
     1921 agccgccagt ttaaccagcg ttctgcctgt ctgatgagaa atggagccat cgccatcggt
     1981 ggacaggatg gtattaatat catcaatcct gccaagatcc ttcctgccca gaaacatgca
     2041 catgtcttgt tcagcggttt cgtacttttc gatcatccgc tgaaggcagg tgaggagttt
     2101 gagggaagag tgcctctgga aaaatcgctc gatactcatc ctgaactgga tctcagttat
     2161 aaggacaagg cgtttaccat acagtttgct tctgaccagg taagtattcc tgcccgttgc
     2221 cgtttcctct atcgcatgaa gggacttgat gacaaatgga tgctgacacc tgagggacgt
     2281 ccggaggcta cctttaccaa tctctcttca ggcagctatg ttctggaggc aaaggtggtg
     2341 aatgctgatg gtagtgtgag cgaagaggtg agcacgctga agatttatat tcatccgcct
     2401 ttctatctct ctatctgggc gttcatcgta tatattatat taataggtgt agctttctat
     2461 ctctaccgta aacgtatgct cgaaaagcaa cgtgtaaaat tcgaactcca gagcaaggaa
     2521 gacagtatca agaagactaa ggagttgaat gaactcaaac tcaacttctt taccaatgtg
     2581 agccacgaac tccgtactcc gctcaccctg attatctcgc cgctggtcaa tatgattaga
     2641 gaagaaagag atgaaagtaa acgcagaaag ctggagatga ttcatcgcaa tgctacccgt
     2701 ttgctcaatc tggtaaacca gattctcgac ttccgcaaga tagaccagaa taaggaaaaa
     2761 cttaccctgt cgcatatcga catcgtgagc ttcgttgaca atatctgtac ttcgttccgt
     2821 actttggcaa acagcaaagt aacgcttgcc ttctattcta cggtgcctag tctgcagatg
     2881 tcgtttgatg ctgataaggt aggaaaaatc gtgaacaacc tcttgagcaa tgcctataag
     2941 tttacgccag atggaggatt tatcaccgtt tctctgagtg ttgcactcca ccagcgtgta
     3001 ggagacaagg attcggatat gctccgcatc tcagtatctg atactggcaa gggcatcagc
     3061 gataaggaga aggaacatgt gtttgagcgt ttctatcagg tcaatggcac tgaaatgcaa
     3121 ccacagggtg gtagcggaat aggtttgaac ctggtaaaga agtttgccga actgcatggc
     3181 ggtaaagtag atgttacaga taatccaagc ggaggaacca tctttatggt agaccttccg
     3241 atagagagca gtaccacctc taattcaacg gcacatctcg gttccttgcg agcagcacct
     3301 atcataacca cggtgcatca ggctactgat gaggatccgg atgcaggtaa gaacgttctc
     3361 tacggaatga gtaaacatgc gcatcagcca ggagaatcga tgatcaagaa gccggtagtg
     3421 ctcctcgttg acgacagtga ggacttccgt gagtttatga acgaagtatt gacagactat
     3481 acggttgttg aggctgtcaa tggtcaggat gcctggaaca agatcatcga ccgtcgtcca
     3541 gacctcatcc tgagcgatgt gatgatgcct gtgatggatg gtaacgaact ctgccggatg
     3601 tgtaaggaca atgacgaaac aacagccata cctttcatca tgctctcggc ccgtatggga
     3661 gatgagcagc gcaaggaaag tctgaagtgt ggtgctgacg agtatattgc caaaccattc
     3721 gatattgata tgttgaatct ctgtattctg aacctcttga agaaacgcaa gaatgtgagc
     3781 acagaatatg taataacaga ggccgaccgc aaatttatag atgaggtgaa tgcttatatc
     3841 cgcgatcata tgagcaatcc tgaaacatcg gtagaatcgc tcagtactca tctttgcatt
     3901 tcacgcgtac aattatataa acgcatgatt tcgctgacgg gtattacacc ttctgagtat
     3961 ctcagaacca agcgtatcaa atttgcagag catctgctgc gctcgggcga cttgaacatc
     4021 agtgaaatag cctataaggt gggattcaat aatccacgtt atttcactaa atacttccaa
     4081 gacacgtatg gcgttacgcc gtctcaatat cgtaagaatc tgtcagaatc agagtagttt
     4141 acgcttctag ttaacatttt atacacatac agataacatt tgcgcacaaa gatacgggaa
     4201 atttctcgta tctttgccgc aaatttttaa actttccttt aaacgtataa aatgagacta
     4261 actaaaacat tattgatttc agcagtgctg ctgatgagtg ccacaggtat gcaggcagca
     4321 ggtttcaacc agaatggtaa ttatctcact gttcagttga agcaacacca gaattttggt
     4381 cctagtcaga ttcgcctcca ggtggtgagc gataagatta tccgtgttca ggctacagcc
     4441 gaacagagtt tccgtaacaa acagagtctg ataatagtgc ctcaaaacag caaggcaaat
     4501 tataaggtgg aagagcaggg agacaatctc atcattacca cagcagccat gcgtgctgtc
     4561 atgaacgagg ctacgggtca gattaccttc tatgacctga aagacaatgt ccttctcaat
     4621 gaggttgctc agggcggaaa gacattcaag ccgttcactg tgcctgaccg tgaaatcggt
     4681 gtagacattg ccaaggttcc tgaagcacag aagcatggat ggtcatggcg tgcgctcttc
     4741 aactctcctg ataacgaggc gttctatggt ctcggacagc atcagagtga ggaactcaac
     4801 atgaagggca agaacgaaga cctcttccag tataatacca aggtgagtgt gcctttcgtc
     4861 atctctaata aaaactacgg catcctctgg gattcttatt cttattgccg ttggggtaat
     4921 ccggaagatt atctccagct caaccgtgcc ttcaaactct atgataagga tggtaaggaa
     4981 ggtcagctga caggtactta tgtggataag aatggtcaaa agattgttcg aggcgaagat
     5041 agcatttact ttgagtatgc aatgcctgag acttctgaga tttgcaacaa gacagataag
     5101 ggcggtattc agaacctgcc aaagggtttt gcactgaatg gctccaaggt ggtgtatgag
     5161 ggttatgtgg aagctccaag taacagcttc tatcagttta tcctctatta tgccggctat
     5221 atgaagattt atatcaatgg caaactggtt gtgcctgagc gctggcgtac agcatggaat
     5281 ccgaactctt ataagtttga aactcctatc aagaagggcg taaagactcc aatccgtatc
     5341 gagtggcagc ctgatggtga tgtttcctat tgcggacttc gcgtagcagc tcctcgttct
     5401 gaggctgaga agaaccagtt gagcatctgg agtgagatgt cgccggatat ggactattat
     5461 ttcatcgccg gtcagaatct cgatgaggtg atttccggtt accgtacgct taccggcaag
     5521 gcttcgcttt atcctaaatg gaccctcggt ttctggcaga gccgtgagcg ctatcagagc
     5581 agcaaggaca tcaaggacaa catgaagaag ttccgcgacc tgcatattcc tgtagacaat
     5641 atcgttcagg actggaacta ctggaaactg gattcatggg gaagtcatga gtttgaggcg
     5701 gcacgctatc cgaacccaca ggctatgctc gacagcgtac atgcgatgaa tggccgcttc
     5761 atgatttccg tatggcctaa gttctatgat acagtcaaga attataagga actcgacagc
     5821 aagggttgga tgtatcatca ggctatcaag gatgatattc acgactggct cggcttccgc
     5881 ggttctttct atgatgccta ttctgatggt gcccgcaaga tgttctggcg ccagatggac
     5941 gagaatcttt ataccaagta taagttcgga atcgatgcat ggtggatgga tgcatcagaa
     6001 ccaaacgttc gtgactgtac cccgatgtgg taccgcaagg ctctttccgg tcctactgcc
     6061 ctcggtacat ctaccgaata tttcaatgct tacagcatcg tgaatgctga tgctatctat
     6121 aacggacagc gcagcgtgaa ccctaaccag cgtgtcttcc tcctgacccg ttccggtttt
     6181 gcaggtgaac agcgctacag tacggctacc tggtctggcg acattgctac ccgttgggaa
     6241 gatatgcgtg cccagatgac agccggtttg aactattcta tggcaggtct gcctttttgg
     6301 ggaatggacc agggcggttt ctgtgtagag aaccgttatg tggcagccca gcaggagttc
     6361 gataagaccg gtaaggaaaa tgctgacttg aaggaatggc gcgagttgca ggcgcgttgg
     6421 aatcagttcg gttgcttcgt acctctttat cgtactcatg gccagtggcc tacccgtgag
     6481 gtctggaaca ttgctccggc agatcatccg gcttacaaga ccatcgtggc ttacgataaa
     6541 ctccgttacc gtctgatgcc ttacctctac agtatggcgg gtatggttca cttcaaggac
     6601 tatacgatga tgcgtggatt ggtaatggac ttcaacggcg atgataatgt ttacgacatc
     6661 aaggatcagt ggatgttcgg tcctgctctc atggcttgtc ctgtaggcga gtatcagaag
     6721 tacagccgca atgtttatct tcctaagcag aagggctggt atgatttcta tacaggtaag
     6781 cactatgccg gtggacagac aatcgtagcc gatgcgcctt tcgataagat tccagtcttt
     6841 gttccagagg gttctattct tcctgtgggt ccagagatgg agtggagcaa tcagaagaag
     6901 gctgagctca tcgacctcta tgtctatgca ggcaaggacg gttcttatac actctatgag
     6961 gatgagggaa ccaactacaa ctacgagaag ggtaagtatg ctatgatcga cttcaagtat
     7021 aatgatgctc agaagaccat tactattgct gcccgtaagg gttctttcga tggtatgcta
     7081 cagaagcgtc gcttcaatat cgtacttgtt agtgataaca accagcaggg tatcagcctc
     7141 gccaaggcgc ctaagggcaa gatggtgaag tatgctggta aggcagttac tgtaaaactg
     7201 aagtaatatg aagaagatat ttgctttagc aatctttcta ttgggcgctc agtcgttgag
     7261 cgcccgtgat cgccagtctt ttgataaagg ctggcttttc actttagcag atagtgccgg
     7321 aatgtcaaag tctgattatt cagaccggca ttggcgaagt ttgaatcttc ctcacgattg
     7381 ggcgatagag ggcgatttct ctccttcgaa tccttcggga gccggtggtg gtgcactgcc
     7441 gggcggcatc ggatggtacc gtaagcactt ctcggtgaat ccgaaggaaa agtatgaccg
     7501 gtttaccatc acctttgatg gagtatatat gaattctacc gtgtatatca atggtcataa
     7561 actcggaacc cgcccttatg gatacagtac attcgagtat gatcttacac cttatattaa
     7621 taagaagggt gataatgtca ttgcggtgaa ggtagacaac agcgaccagc ctaacagccg
     7681 ctggtattcc ggttgcggta tttaccgcca tgtctggctc accaaaacca tgaaatctgc
     7741 ttatattccc caatggggac agtatgtagc aacttctcca cagggtgatg tcagggtgaa
     7801 ggtggatttc gctgcttccg gtaataagat gaaactctct gtccgtaata caatctatga
     7861 tgctgccgga aagatcgtag ccaagagtca gggtgttcgg gaacagaaat tcaaggtgaa
     7921 gaatccgcat ctctgggaca tcggaaaggg atatctctat acagttaaga gcgagctgtt
     7981 agtaaatggg aaggtagtgg atgttgctac gtcaactgcc ggtttccgcg atgtgaagtt
     8041 tgatgcaaag aagggtttct tcctcaatgg caagaatctc aagataaatg gtgtctgtga
     8101 gcatcatgat ttcggttgcc tgggtgctgc tgtcaatgaa gatgcgatgc accgtaaact
     8161 taccatcctt cgcgatatgg gcgtgaacgc tatccgaagc agtcataatc ctccggcacc
     8221 agaactcctg aacatgtgcg attcgatggg tttcctcgtg atggacgaga gtttcgacat
     8281 gtggcgccgc aagaaatcga atggcgatta tgcccgtttc ttcgatgaat ggcataagaa
     8341 agacctgtct gatctcatca agcgtgaccg taatcatcca agtatcatta tgtggagtat
     8401 cggtaatgaa gttctcgaac aatggtcgga tgtggctgct gatacgctca gtctggagca
     8461 ggctaacctg attctgaatg ccggtcatga tgcttctagc ttgtcacata gcaatgaact
     8521 gagtgtcaat tcgcttctta cccagcatct ggcaaaaatc gtgaaggagt atgatccttg
     8581 gggcacacgc cctgttactg ctggctgcaa tgagcccgac ccgaagaatc acctctttaa
     8641 gagtggggct attgatgtta taggtttcaa ttatcaccat cagtgggtga aggatgtgcc
     8701 gaagaatttc cctggcaagc cttttattct gtcggagagt gtttctgcct tgcagactcg
     8761 tggctactat atgatgccta gcgacagcat ttatactgcg ccaaaggaat ggtggttgcc
     8821 ttataccgat ccattgttta tgtgttcggc ttatgataat ttccacgcat catggagtag
     8881 tacccatgaa gaaacctggg atgtggtgaa gcacaacgac tttgtgggcg gacagtttat
     8941 ctggaccggt ttcgattata tcggtgaacc tactccttat gcttatcctg cccgtagcag
     9001 ttattttggc attatcgatt tggcgggtct tccaaaagac agctattata tgtatcagag
     9061 tgagtggact cagaaagatg tgcttcatct cttccctcat tggaactggc tgccgggaca
     9121 gaccatcgac atgtggtgtt attataatca tgccgatgag gtagaactct ttatcaatgg
     9181 caagagtcag ggcatccgta agaagacagt ctacggtgca aagaacgaag gcgatgcttt
     9241 cagaaagagt actgaatatc acgtgatgtg gcgggtaaac tttgaaccgg gagaagtgaa
     9301 ggttgtagcc agaaagaatg gtaaagttct tagagagcag gtcataaaaa cagcaggagc
     9361 tcctcatcat cttgtgttga agaagactta tcagggctgt caggcttttg gctcttctga
     9421 tccgaccacc tttgtagagg tgaatgtggt agataaagac ggcaatctct gtccgaacgc
     9481 agataaccag attttcttct ctgtttcagg agaacaggat gcaagtggtc atggtttcct
     9541 gaaaacgcca aagattctgg gaacagataa tggatgtcag acttctttgg agcgtttcac
     9601 cgattcacat cgcaaggcat tcttcggaaa atgtgtcgtt gtgataaaag gaaagggaac
     9661 cctcaaggca caggcagtag acttaaagga tgcttctgta gctttgtggt tatag
//
