LOCUS       NZ_CP102288            22477 bp    DNA     linear   CON 29-JUL-2024
DEFINITION  Segatella copri DSM 18205 chromosome, complete genome.
ACCESSION   NZ_CP102288 REGION: 243976..266452
VERSION     NZ_CP102288.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN20222705
            Assembly: GCF_025151535.1
KEYWORDS    RefSeq.
SOURCE      Segatella copri DSM 18205
  ORGANISM  Segatella copri DSM 18205
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Prevotellaceae; Segatella.
REFERENCE   1  (bases 1 to 22477)
  AUTHORS   Cheng,A.G., Ho,P.Y., Aranda-Diaz,A., Jain,S., Yu,F.B., Meng,X.,
            Wang,M., Iakiviak,M., Nagashima,K., Zhao,A., Murugkar,P., Patil,A.,
            Atabakhsh,K., Weakley,A., Yan,J., Brumbaugh,A.R., Higginbottom,S.,
            Dimas,A., Shiver,A.L., Deutschbauer,A., Neff,N., Sonnenburg,J.L.,
            Huang,K.C. and Fischbach,M.A.
  TITLE     Design, construction, and in vivo augmentation of a complex gut
            microbiome
  JOURNAL   Cell 185 (19), 3617-3636 (2022)
   PUBMED   36070752
REFERENCE   2  (bases 1 to 22477)
  AUTHORS   Cheng,A.G., Jain,S., Meng,X. and Fischbach,M.A.
  TITLE     Direct Submission
  JOURNAL   Submitted (29-JUL-2022) Chem-H, Stanford University, 290 Jane
            Stanford Way, Stanford, CA 94305, USA
COMMENT     REFSEQ INFORMATION: The reference sequence is identical to
            CP102288.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Date          :: 2021
            Assembly Method        :: Unicycler v. 0.4.8
            Assembly Name          :: Prevotella-copri-DSM-18205-MAF-2
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: 100x
            Sequencing Technology  :: Illumina HiSeq; Oxford Nanopore
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_025151535.1-RS_2024_07_29
            Annotation Date                   :: 07/29/2024 03:59:40
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,796
            CDSs (total)                      :: 2,718
            Genes (coding)                    :: 2,663
            CDSs (with protein)               :: 2,663
            Genes (RNA)                       :: 78
            rRNAs                             :: 5, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 5, 5, 5 (5S, 16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 13 of 55
            Pseudo Genes (incomplete)         :: 44 of 55
            Pseudo Genes (internal stop)      :: 9 of 55
            Pseudo Genes (multiple problems)  :: 11 of 55
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..22477
                     /organism="Segatella copri DSM 18205"
                     /mol_type="genomic DNA"
                     /strain="DSM 18205"
                     /host="Homo sapiens"
                     /culture_collection="DSM:18205"
                     /type_material="type strain of Prevotella copri"
                     /db_xref="taxon:537011"
     gene            1..4134
                     /locus_tag="NQ544_RS01005"
                     /old_locus_tag="NQ544_01005"
     CDS             1..4134
                     /locus_tag="NQ544_RS01005"
                     /old_locus_tag="NQ544_01005"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007367200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hybrid sensor histidine kinase/response
                     regulator transcription factor"
                     /protein_id="WP_006847808.1"
                     /translation="MKRYKSCTLIILLLLASVLQAYAHISRNMFMLSNLNADNGLSSP
                     RVYSIVEAEDGAMWISTKRGVDRYNGQQVTNYTLYTEMPYSDACGRSIKLTKDAQHLI
                     YAYDNKGKVYIYDKRKDAFVLKCNLQNILGGSIVLNELLVDEKGNFWLAMDRGIYCLS
                     AATDGKEIVRETAKGRFVLKNTYINHIQFIGQKLLIGTFKDVYCYSMSARKLEKKISG
                     SSVVSSYHDIVGHRIWLGTFHEGVKVVDDRTWKLIKSADFQSLQNIPKIPVRSIILYD
                     KQTLLMAVDGAGIYAYDSSNKQTKLLLDTDGRPGNMLNGNGLYTLCCDRFGDLWTGSY
                     SGGVDLAIPMKHTLEYITHEYLNNQSLIDNCVNDVFQSRDGKIWYATDKGVSVYDAQT
                     RLWHHGLYNKVALTICQTVDGRILVGTYGNGVYQVHADGTSMPAYSVETGMLKSDYVF
                     SLLTDSDGNIWVGCLDGDMACFPSDKYNLNGTGKSVFYLPVNEVQCITESLDKRFIAV
                     GTSHGGYLIDKREPLHPRRFFYPEQYPEKDINLFVNSMAFQDSRHIWIGTDGGGLYDY
                     DFLTKKFKRYTNQDALPSNTVYGLIKGINGNLWISTDKGLAFMKQGKIVNLNIFKGME
                     REYNRMSVACTSDGRVLFGSNDGVVALTPMFAKGLNYAAPLRIHSVEVEGVERSDYWN
                     ECLFEMLKEGKLKLSHNENTLVVSFESINYQYQYDIQYQYYLEGYDRNWSKPSSNQLA
                     RFVNLPSGSYVLHVKAICRSNGRELGETTLEIHIAQPWWNTWWAWIIYLCIFAAILYF
                     VWQYYKERLQRKYYDEKINFFVNTAHNIRTPLSLVLAPLDNLANDSSLSEKSRGFLDV
                     AHRNGNKLLKMVTELLDFQKIEQSAEQVRLQDIELPMLLRVQLEKFVLAAQEKHIQLC
                     IETCPQQQIHSDVKMMDLILENLLSNAIKYTPQGGKVSLSASVEGKMAMIHVCDTGIG
                     IPKAEIKSIFKTFFRASNAINSQEMGSGLGLMLTRKLVEKLGGKLSFVSEEGKGTTFC
                     VKMPLGHVTDSSVRLVGEKKNVATESSLAEDKHDETCQTVSSAVQQDADVSTDTLLFV
                     DDNEDLRKYIRMTFGDSYQVVDVESAEAALKYLKEGGVCDIVVSDVMMPGMHGDEFCR
                     SIKENKETSWLPVILLTAKAGRDFMIEGLGLGADDYIAKPFDTAILASKVASILKNRR
                     RLSQYYMDRSLALVKGEVASESASSEQIVGSDSSYEHLEPTGASEEKKDDTVLNKQGQ
                     TFEKVAEAVLDPQDQAFVDKATRLVLAHLSDTDFNIDRLCREMAMSRTLFYGRLKTLT
                     GKSPQDFMRLIRLEQAAIFLKQGDSVLDVSVKAGFVNVKYFSTVFKKHFGVSPSKYL"
     gene            4314..5534
                     /locus_tag="NQ544_RS01010"
                     /old_locus_tag="NQ544_01010"
     CDS             4314..5534
                     /locus_tag="NQ544_RS01010"
                     /old_locus_tag="NQ544_01010"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007367201.1"
                     /GO_function="GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA]"
                     /GO_process="GO:0071704 - obsolete organic substance
                     metabolic process [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 5 protein"
                     /protein_id="WP_040553145.1"
                     /translation="MKRNFLKISLFLIGVFTCFSCEASTLHSSSSSDGVGESMPTAQQ
                     WNKDVVGWNLGNEFECSAPGQDGESMQIGNPDGSIHAETAWGNPVVTKKMIQAVKKAG
                     FNAIRIPIRWQCHITNAQAMSIDKAWIARIKEVVGWCLDNGLKVIINVHHEKWLESRP
                     TYQYKEENCQKLALLWMNIASEFANYDSRLAFAGTNEVHIRDNWGKPTAENLEVQNAY
                     NQIFVDVVRATGGNNAKRHLILQTYVCNPWFGIENGDFIIPKDAEGNGNNYMSVEFHY
                     YQPWSYAGDCTYDYWGDAYKDAGKIPADNEKTMTDFFDKAVNTWSNKGLGIVIGEWGV
                     TDHYKSNSEKVHENMTYYCKFLTTEARKRGFSTFVWDNNHFGNGSEKYGIFDRFKSMK
                     VNAPWILEGIFGKE"
     gene            5563..8739
                     /locus_tag="NQ544_RS01015"
                     /old_locus_tag="NQ544_01015"
     CDS             5563..8739
                     /locus_tag="NQ544_RS01015"
                     /old_locus_tag="NQ544_01015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004359710.1"
                     /GO_component="GO:0009279 - cell outer membrane [Evidence
                     IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SusC/RagA family TonB-linked outer membrane
                     protein"
                     /protein_id="WP_040553143.1"
                     /translation="MRKKTMFLGLLGAGLMWMPASAILAAQMNSAAMSVQQNQGIKGT
                     VVDATGETLIGASVKVAGTTNGAVTDIDGNFTLNCKPGVTLEVSYIGYKTMTVKAANG
                     MKITMQEDGKALNEVVVTALGIKRDRKALGYGLEEVKGEELTKAKETNVINSLSGKVA
                     GLVVQNTAGGASGSTRVLLRGNTEMSGNNQPLYVVDGVPLDNTNFGSAGEAGGYDLGD
                     GISAINPDDIETMTVLKGPAASALYGSRASHGVILITTKKAEKDKVAVEYNGSFTIDT
                     QLAKWNDIQEVYGMGYGGKLPTSSTSGTNSSWGPKADDFVYKYFDGQEHAFMMYPNNA
                     SDFFRTGLTAQNSAILSVNSGKTGMRFSFTDMRNKDILPNTNMSRDNFNLRVNTSAGP
                     VDFDFTANYTREDVKNRPALGDSQSNVGKNLMTLAGTYNQVWLKNYEDADGNYQNWNG
                     NDQYNKNPYWDLYKNSNTSKKDVFRLTGKAIWNIDKHLKLQGTIGTDITNMNFEDFIA
                     KTTPGTPAGKLTDQIFNNRTLNAELLALYNNSWGDFDVNATAGGNIFKVNNKTITNTG
                     LNQQMNGIKNIMNYQEQNTRESMYKKQISSLYASASIGYKHTYYLEGTIRGDKSSTLP
                     TSNNTYVYPSVSGSLVFSEFIKNKKIINYGKVRASWAKVGSDTDPYQLALNYSTGKYS
                     YAGYTIGMISNATQPNKDLKPTMTGSYELGLEMKFFNGRLGLDATYYNQNSKDQILSL
                     ASTTTSGYSYRLVNAGEIQNKGIEIALNGRLLQIKDFGWDMGVNFSKNTNKVKSLVDG
                     MDYFELAKATWCGVSVGAEVGENYGAIRGKDFKRTADGQVIINPTSGLPEVDQTVKTI
                     GNSSWDWTGGFYTTFSYKNFRLSASFDVKVGADIYSMSMNSAYKTGKAKQTLAGRDEW
                     YASEEAREAAGMTDEQWRAAGNAKGFVAPGVIDNGDGTYRPNDIAVNPETYWKAIANN
                     VQSAFVYDNSYVKCREITFGYTFPESLLGKWVKGLNVSFVARNPFIVWKNIPNIDPDS
                     SYNTSGLGLEYGSLPSRKSYGINVNVKF"
     gene            8764..10551
                     /locus_tag="NQ544_RS01020"
                     /old_locus_tag="NQ544_01020"
     CDS             8764..10551
                     /locus_tag="NQ544_RS01020"
                     /old_locus_tag="NQ544_01020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009434644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SusD/RagB family nutrient-binding outer membrane
                     lipoprotein"
                     /protein_id="WP_006847804.1"
                     /translation="MNNIIKKYIGKGGFAMAMLLMATGGVMTSCSDDMMERTNTDKTK
                     VNQLDPNAQLTTSLLQTYGDFSLMDTYRNYITGFTQHFAGGWNVTNYAGAVHHEDDIA
                     RRIWDRYYEVAIKNLVDAIHKSEDKANLNAALRIHRVYLLSVLADTYGDIPASEAGLG
                     YISGISNPKYDTVEDLYGWFFTELDACEQQLGTGTDHISGDVTSMGGDVAKWKKYANS
                     LRMRYAMRISDVNPSKGQEEFEKAMNHADGYIASAADDAYIKYADSPYTYYDGANDYD
                     FRTNALGEILYGQDPSSPTFVSSTLFYQLQNTGDPRLYRICRHYYNIKRSQVKPDKEQ
                     NIDLTDEVLAYFQRNNIGEEPCNTGSAWYENWMNVADAAEFPTLAKLAEQDANSYDNS
                     DYRARLMRPCLNIDFEMPSCPGILITSAEVDFLLAEAKTKGWNVSGDAESHYEAGVRA
                     SMEMLNNYYLTSNKISEDEINAFIANNQLGENPKQTINTQAWILHMMNPSEAWANMRR
                     SDYPALLDRSRLATFPGDGFVYDDPNMSMPTRLRYPELEGQYNSVNYKAAIERMGGTD
                     DWHKKLWWDKSDVNVQGDFNPPYGKGYIK"
     gene            10629..11615
                     /locus_tag="NQ544_RS01025"
                     /old_locus_tag="NQ544_01025"
     CDS             10629..11615
                     /locus_tag="NQ544_RS01025"
                     /old_locus_tag="NQ544_01025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018363140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_228023612.1"
                     /translation="MNQYMGKVLKSWMMLFAISFALAGTATLSSCSSDDDPFFTVSED
                     DDPRILNTDLADQKLDRKTKLNLEIKVTPVHYTTVTWLLDDTQIAEGTTIDQTLPVGN
                     HTLKIVATTTKGKSTSRTLKVTVTPAADDPALGTNAIELWVAPGAETTIHKCKNLGTV
                     TKVMVGGKEVVFEVLEEGTALKLTAPTGLENGDYDITLVDGEGNQFSGGIIKVTTEAR
                     PSMENTLWEGEFSVTWGTPFEALKDTFLSKVKAGTILRVYVDGNGQGTATTAWWNNIL
                     TGKGDPDRNDFMVTGPATWEFELTDLSIQLLTEQNGFLLVGDGYTVKKVTIE"
     gene            11668..13986
                     /locus_tag="NQ544_RS01030"
                     /old_locus_tag="NQ544_01030"
     CDS             11668..13986
                     /locus_tag="NQ544_RS01030"
                     /old_locus_tag="NQ544_01030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007367205.1"
                     /GO_function="GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 3 N-terminal
                     domain-containing protein"
                     /protein_id="WP_006847802.1"
                     /translation="MKKILLSISLLALAYTASANVPVIKSDPKIEAQVEQTLKKLTLE
                     EKIGQMMELVTDLFGANDKNGVFYIDEHKTDSILSRYKIGSILNAPNTCAPTAKQWEK
                     YIAQIQKISMKRIGIPCVFGLDQNHGSTYTQGGTLFPQNINVAATFNREIARRSAEAT
                     AYETRAVSIPWTYSPTVDLGRDARWPRIWENFGEDCYLSSEMGKAMVYGFQGEDPNNI
                     DQYHIATSMKHFMGYGVPWTGKDRTPAYISPADLREKHFAPFLAGLQAGALTVMVNSA
                     SVNGMPMHANKDILTGWLKEETGWDGVLITDWADINNLYTREMVAKDKKDALRIAINA
                     GIDMIMEPYSCDACGYLVELVKEGKIPLSRIDDACRRVLRMKYRLDLFKNPTQKLKNY
                     PKFGGEEFAKLALEGATESMVLLKNEGNILPLQHGKKILLTGPNANQMRCLDGGWSYT
                     WQGHRADEFAGKYNTIYEAFCNEYGKENVILNQGVTYNEKGKYWEENEPQIQGAVAAA
                     KDADVIVACIGENSYTETPGNLTDLWLSENQRNLVKALAQTGKPVILVLNEGRPRLIA
                     DIEPLAQGIINILIPGNMGGDALANLVSGKSNFSGKMPYTYPKEINSLVNYDFKKSEE
                     VGTMEGAYDYNAKITQQWGFGYGLSYTTYKYSNLKVSQSDFRHGDIIKVSVDVKNTGK
                     VAGKESVLLFSSDLIASMVPDGRRLRAFDKVELQPGETKTMTFELKADDLAFVGWNGK
                     WRLEEGDFKLMIADQSADIHCTDTYQWSTANR"
     gene            14179..15495
                     /locus_tag="NQ544_RS01035"
                     /old_locus_tag="NQ544_01035"
     CDS             14179..15495
                     /locus_tag="NQ544_RS01035"
                     /old_locus_tag="NQ544_01035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009237322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombination protein RmuC"
                     /protein_id="WP_006847801.1"
                     /translation="MEIVIGIIIGLAIGFFVGKLMEAKSAGEEKTQLVAKAQVLAANI
                     EQIKLHHASEVQSMKSQMENERLYAAKLRAESDQQWAQKLESLKQEMQRMTIEQQKVA
                     AEQLAAKQSALQENNRLQMDELLKPIKEQFADFKKSVEESKTQNEVNKKELQNTFEAT
                     MKLFQQEQQQAVLNLKEQTEKIGSDAANLTKALKGDSKMQGDWGEMVLETILENSGLR
                     KNEEFFIQEYTKDEEGKNYRPDVIVRFPEGRSVVIDSKVSLTAYSDALAAEDEAEQER
                     LMKAHALSVRKHIDELAAKDYSKLVDDAIGFVLMFIPNETSYIAAMKQQPDLSRYAYQ
                     KKIIIISPSNLLMALQLAYNLWQYDRQNKNVEKIVKTAADLYDKVAGFEDTFMSVGDL
                     ITRLSGTFDKAKKQLYDGTGNVMRRVESLKGLGVTPKKQIKELDNL"
     gene            15743..17332
                     /locus_tag="NQ544_RS01040"
                     /old_locus_tag="NQ544_01040"
     CDS             15743..17332
                     /locus_tag="NQ544_RS01040"
                     /old_locus_tag="NQ544_01040"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008566214.1"
                     /GO_function="GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
                     /protein_id="WP_006847800.1"
                     /translation="MKLNEILSDSFNAAEWEAKGYELPKYDIAAVAKKTHDEPTWVHF
                     GAGNIFRAFPAAILNDALNTGKYDRGVIVAESFDYEIIDKAYRPYNNLSLLVSLQSNG
                     TIEKKVIASITESLKADKQFGEDWARLVQIFQAPSLQMVTFTITEKGYSYNDADLSRG
                     LDAVFAMGKLTALLYERYKAGKLPLTLQSTDNCSHNGDHVKAGVKAYAERWAQAGIVE
                     AGFVDYINDSSKITYPWSMIDKITPRPHEKVQAMLAEDGFEDNNTIITEKHTFTAPFV
                     NAEEVQYLVCEDTYTNGRPPLELGGALYTTRKTVDEVETMKVTTCLNPLHTAMSIYGC
                     MLDYTLISAEMADEDLRAFIQKIGYIEAMPVVTDPGVLNPYEFIGTVINKRLPNPFMP
                     DAPQRIATDTSQKLSIRFGETIKKYIDRGLDKSNLVLIPLVLAGYARYLKALDDNLKP
                     FEPSSDPLLAELQAIVAPLEVGKADQDYSCLKNLYSRKDVFGLDLYEAGFGEQIEGMV
                     KELFAGKGAVRATLHKYVSAR"
     gene            17366..18637
                     /gene="uxuA"
                     /locus_tag="NQ544_RS01045"
                     /old_locus_tag="NQ544_01045"
     CDS             17366..18637
                     /gene="uxuA"
                     /locus_tag="NQ544_RS01045"
                     /old_locus_tag="NQ544_01045"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004377351.1"
                     /GO_function="GO:0008927 - mannonate dehydratase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006064 - glucuronate catabolic process
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="WP_006847799.1"
                     /translation="MERTWRWFGKKDKITLAQLKQIGVEGIVTALHDVPLGEVWTREK
                     IHELKEYIESYGMKWSVVESLPVVETLKYGGPDRDHQIEVYKESLRNLGEEGIKCICY
                     NFMPVLDWARTDLSHDNPNGANNLYMNWGEFAYFDIYILQREGAREDWAEFSKEHKWG
                     RDLVAEADEIKKTSTPEQDHALVENIIIKTQGFVSGNFSEGDSAPVQKFRDLLKLYDG
                     IDKKKLQENMKYWLEAIMPICDEYDINMCVHPDDPPYPVFGLPRIIGRAEDIQWMLDA
                     VPNKHNGLTFCAGSFSAGEHNDCVAMAKQFADRTHFVHLRSCYIFPNGNFTEASHLGG
                     RGHLIELCRIFEKAEQEGKCNSGRRLPMRVDHGMTFTDEPGGVFDESNHGHNAGYTLL
                     GRMFAMGQIQGVIATVDDELGIEYKQPGFYD"
     gene            complement(18752..19159)
                     /locus_tag="NQ544_RS01050"
                     /old_locus_tag="NQ544_01050"
     CDS             complement(18752..19159)
                     /locus_tag="NQ544_RS01050"
                     /old_locus_tag="NQ544_01050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004374479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_006847798.1"
                     /translation="MKKILYFVAALAAASFITTMGTSCKFAPDQHDGDTVAASEFYPI
                     DTSAAHAKKMAKIAAIKNGKDSVGIYYVGSNSTKDLIELVSYPSRRDTMMYSKTRHIK
                     VKGNADINHVVRVDFYLHNGKDSLVKYVEEVVL"
     gene            complement(19982..22477)
                     /locus_tag="NQ544_RS01055"
                     /old_locus_tag="NQ544_01055"
     CDS             complement(19982..22477)
                     /locus_tag="NQ544_RS01055"
                     /old_locus_tag="NQ544_01055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006951838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH36-type glycosyl hydrolase domain-containing
                     protein"
                     /protein_id="WP_006847796.1"
                     /translation="MAEKKYGHFDDANREYVITDPKTPWPWINYLGNEDFFSLISNTA
                     GGYSFYKDAKFRRITRYRYNGVPMDNGGRYFYIKDGDTVWNPGWKPCKTPLDSYECRH
                     GMNYTRITGSKNGVEASVLFFVPLHTWAEVQKMTLKNQTEEEKTLKVFSFAEWCLWNA
                     ATDMENFQRNFSTGEVEVEGSTIYHKTEYRERRNHYAFYTVNTEIQGYDTDRESFIGL
                     YNEFAEPEAVMEGKPRNSFAHGWSPIASHYIEVTLQPGESRDLIFLLGYVENEQDKKF
                     SAKKVINKEKAHQLIAKFDTTEKVDAAFAELNQYWDNLLNIFTVKSGNDKLDRMVNIW
                     NQYQCMITFCMSRSASFFESGIGRGMGFRDSNQDLVGFVHQIPTRARQRIIDIASTQF
                     PDGGCYHQYQPLTKRGNNDIGGGFNDDPCWLIFGTVAYIKETGDFSILAEQVPFDNQP
                     GTEVSLFEHLKISMNHVINNLGPHKLPLIGRADWNDCLNLNCFSWDPNESFQTTENKG
                     EGSKAESLMIAGLFVVTGKDYVALCKQLAKEAMESKEGEIAGLAEEDYLTEAERMQQA
                     VDEMNEAVKQHGWDGEWFLRAYDFFGNKIGSDENEEGKIFIESQGWCTMAGIGLEEGL
                     CDIALDSSKKRLECEHGLVLNNPAYTTYHVEMGEISSYPEGYKENAGIFCHNNPWVII
                     GETVAGRGNDAWSHYTKILPSYVEEKYQTLHKVEPYVNCQMVAGKDAAKPGEGKNSWL
                     TGTAAWMWYTVSEFILGIKPDYEGLLIDPCLPSTAKEYEVTRKFRGGEYHITVKNPSG
                     NQKGVKQITVDGTPISGTIIPCSQGKHEVVVEM"
ORIGIN      
        1 atgaaacgat ataaatcctg cactctcatt atattgctgc tgttggcatc ggttcttcag
       61 gcatatgcgc atatttccag aaatatgttc atgctttcca atctcaatgc tgacaatggt
      121 ctttccagtc ctcgagttta ttctattgtc gaggcagagg atggtgccat gtggataagt
      181 actaagcgtg gagttgaccg atataatggg caacaagtaa ccaattatac tttatacaca
      241 gagatgccgt atagtgatgc ttgtggtaga agtattaaac tgactaagga tgcgcaacat
      301 ctgatttacg cctacgacaa caagggaaag gtgtatatat atgataagag gaaagatgca
      361 tttgtcttga aatgtaatct tcagaatatt ttaggtggaa gtatcgtgtt gaacgaactg
      421 ttggtagacg aaaagggcaa tttctggtta gctatggata gaggcattta ttgcttatca
      481 gcagctactg atggaaagga gatagttcgg gagacagcta agggtaggtt tgtattgaaa
      541 aatacctata ttaatcatat ccaatttata ggtcagaaac tcttgatagg aacatttaaa
      601 gatgtttatt gctattcgat gtctgcccgg aagttagaaa agaagattag tggcagttct
      661 gtagtatcct cttatcatga tattgtggga catcgtatct ggctgggtac ttttcacgaa
      721 ggagttaaag tagtggatga tcgtacttgg aagctgataa aatctgctga tttccaatct
      781 ttgcaaaaca ttcctaaaat tcccgtacgt tcaatcattt tatatgataa gcagactctt
      841 ctgatggctg tagatggagc tggaatatat gcttatgaca gttcgaataa acaaaccaag
      901 ctcttgcttg atacagatgg acgtccgggt aacatgctga atggtaatgg attatatacc
      961 ttgtgctgcg atcgttttgg cgatttatgg acaggctctt actcgggagg agtagatttg
     1021 gcaataccga tgaaacatac attggaatat atcacacatg aatatctcaa caatcaatca
     1081 ctgatagata attgtgtgaa cgatgttttc caaagccgtg atgggaaaat atggtatgcc
     1141 acagataaag gagtaagtgt ctatgatgcg cagactcgtc tttggcatca tggattatat
     1201 aataaggtgg cgcttacgat ttgtcagact gtagacggca gaattctggt tggtacctat
     1261 ggtaatggcg tatatcaggt tcatgctgat ggcactagta tgcctgctta ttctgtagaa
     1321 acaggaatgt tgaagagtga ttacgtattc agtcttttaa ctgatagcga tggtaatatt
     1381 tgggtgggat gtttggatgg agatatggct tgtttccctt cagataaata taatttgaat
     1441 ggaacgggaa agtcggtatt ctatctgcct gtcaacgaag tgcaatgcat cacggaatca
     1501 ctggataagc gttttattgc tgtaggaact tcgcatggag gctatttgat tgataagcgt
     1561 gaacctttgc atcctcgtcg tttcttttat cctgaacagt atcccgaaaa agacattaat
     1621 ttgtttgtca acagtatggc ttttcaggat tcccgtcata tctggattgg aacggatgga
     1681 ggaggactct atgattatga tttcttgaca aagaagttta agcgctatac gaatcaggac
     1741 gctttgcctt ctaatactgt ttatggactt ataaaaggta ttaatggcaa tctatggata
     1801 agtacggata aaggattggc gttcatgaaa caggggaaga tagtaaacct caacatcttt
     1861 aagggaatgg aacgtgagta taaccgaatg tctgttgcgt gtacttcaga tggcagggtg
     1921 ctttttggca gcaacgatgg agttgtcgct ttgactccta tgtttgccaa aggtttgaat
     1981 tatgccgctc cacttcgtat tcatagtgtt gaggttgaag gtgtcgaacg ttccgattac
     2041 tggaatgaat gtctctttga aatgttgaag gaaggcaaat tgaaacttag ccataatgag
     2101 aatacgctgg ttgtttcttt cgagagtatc aattatcaat atcagtatga tattcaatat
     2161 caatattatt tggaaggata cgaccgtaat tggagtaaac catcttctaa tcagttggca
     2221 cgatttgtaa atttgccttc gggcagctat gtgcttcatg taaaggctat ctgcagaagt
     2281 aatggtagag aattgggaga aacaactttg gagattcata tagcccaacc ttggtggaat
     2341 acctggtggg catggattat ctatctctgt atttttgctg ccattttata ttttgtctgg
     2401 cagtattaca aagagcgctt acagcgaaag tattatgatg agaaaatcaa tttcttcgtt
     2461 aatactgccc ataacatacg tactcctttg agtctcgtgt tggctcctct tgataatctg
     2521 gctaatgatt ccagcttgag tgagaaaagt cgtggattct tggatgtggc gcatcgcaac
     2581 ggcaacaaac tattgaagat ggttacagaa ttgcttgact tccaaaagat agagcagtct
     2641 gccgaacagg ttcgcctgca agatatagaa ttgccgatgc ttttacgtgt gcagttggaa
     2701 aagtttgtat tggcagctca ggagaagcat attcaactgt gtattgaaac gtgtccgcag
     2761 caacagattc attctgatgt caaaatgatg gatctgatat tggaaaatct tctctcgaat
     2821 gctatcaaat atacacctca aggtggaaag gtttcgttgt cggcttctgt tgaaggtaag
     2881 atggctatga ttcatgtatg tgatacaggt ataggtattc caaaggccga aattaagagt
     2941 atcttcaaga ccttcttcag ggcttctaat gcgataaatt ctcaggaaat gggaagtgga
     3001 ttaggactga tgcttacacg aaagcttgta gagaaattag gaggaaagct tagtttcgta
     3061 agtgaggaag gaaagggtac tactttctgt gtgaagatgc cattaggtca tgtaacagat
     3121 tcttctgtcc ggcttgtggg agaaaagaaa aatgttgcaa ctgaatcttc tttagcagaa
     3181 gataagcatg atgaaacttg ccagactgtg tcttctgcgg ttcagcagga tgctgatgtt
     3241 tcaacggata cacttctttt tgtcgatgac aatgaagatc ttcgcaaata tatcagaatg
     3301 acttttggtg attcttatca agtagttgat gtggagagtg cagaggctgc cttgaaatat
     3361 ctgaaagagg gcggggtatg tgatatcgtt gtttctgatg tcatgatgcc gggaatgcac
     3421 ggagacgagt tttgtcgcag catcaaggaa aataaggaaa catcatggct gcctgttatc
     3481 ctgctgactg ctaaggctgg tcgtgacttt atgatagagg gactcggact tggtgctgat
     3541 gactatatag ccaagccatt cgatactgct attcttgcga gtaaggttgc cagtattttg
     3601 aagaatcgtc gccggttgag tcagtattat atggacagaa gccttgctct tgttaaagga
     3661 gaggttgctt ctgagtctgc ttcttccgag cagattgtgg gttctgattc ttcctatgaa
     3721 cacttggaac ctactggagc ttctgaagag aaaaaggatg atacagtctt gaataagcaa
     3781 ggccagacat tcgaaaaagt ggcagaagct gttctggatc cgcaagacca ggcttttgta
     3841 gataaagcta cccgtttggt gttggctcat ctgagcgaca cagactttaa tatcgaccga
     3901 ctctgtagag agatggcgat gagcagaacg cttttctatg gtaggctgaa gactcttacg
     3961 ggcaaaagtc cgcaggattt tatgcgtttg atacgtctgg agcaggctgc aatcttcctg
     4021 aaacaggggg atagtgtgct ggatgtatct gtgaaagccg gttttgtaaa tgtgaagtac
     4081 tttagtactg tatttaaaaa gcactttggg gtttctccaa gtaagtatct gtaaattaga
     4141 gttttaaatt caaagaaaag gtttctgttt agacgatatg tctgaattga aacctttttt
     4201 tgtttgttat ctaaccctct gaaagttcct tttctttatc tttgcaacca gattctgtta
     4261 cgtaagttaa acagttaatt aaaaaacgaa acaataacaa tataaacata aaaatgaaaa
     4321 ggaacttttt gaaaattagc ctctttttaa taggcgtctt cacatgtttt tcatgcgaag
     4381 caagtacgtt gcactcatcc agcagttctg atggtgtagg cgaatccatg cctactgccc
     4441 agcaatggaa taaagatgtt gtggggtgga atcttggcaa tgaattcgag tgctcagctc
     4501 ctggccagga tggtgagtcg atgcagattg gcaaccctga tggttctatc catgcagaga
     4561 cagcctgggg caatcccgtt gttaccaaga agatgataca agccgtgaag aaggcaggtt
     4621 tcaatgccat ccgtattcca atccgttggc agtgccacat taccaacgct caggcgatga
     4681 gcatcgacaa ggcttggatt gctcgcatca aggaggtggt gggctggtgc cttgacaacg
     4741 gtttgaaggt tatcatcaat gtgcatcatg aaaaatggct cgaaagtcgt cctacctatc
     4801 aatataagga agaaaactgc cagaagcttg cgctcctctg gatgaatatc gcctctgagt
     4861 ttgccaatta tgacagtcgc ttggctttcg ccggtaccaa tgaggttcac atcagggaca
     4921 actggggcaa acctactgcc gagaacctcg aagtgcagaa tgcttacaat cagatattcg
     4981 tggatgtggt tcgtgccaca ggcggcaaca atgccaagcg ccacctcatc ttacagactt
     5041 acgtttgcaa cccatggttt ggcatagaga atggagattt catcattccg aaggatgccg
     5101 aaggcaatgg caacaactat atgagtgtgg aattccacta ctatcagcca tggagctacg
     5161 ccggcgattg cacctacgat tactggggtg atgcctacaa ggatgctggc aagatacctg
     5221 cagacaacga gaagacgatg acggatttct tcgacaaggc ggtgaatacc tggagcaaca
     5281 aaggactggg tatcgtaata ggagagtggg gagtaaccga tcactataag tcaaactcag
     5341 agaaagtgca tgaaaacatg acctactact gtaagttctt gactacggag gctcgcaaac
     5401 gaggcttctc tactttcgtt tgggacaaca accacttcgg caacggctct gagaagtatg
     5461 gcatcttcga ccgtttcaag agtatgaagg tgaatgctcc ttggattctc gaaggaatct
     5521 ttgggaaaga ataatgttaa actaaaaaca aaaatatcaa ttatgagaaa gaaaactatg
     5581 tttctcggcc tgcttggtgc aggtttgatg tggatgcctg cttctgccat tctcgctgcc
     5641 cagatgaaca gtgcagcgat gagcgttcag cagaaccaag gcatcaaggg tacagtggtg
     5701 gatgccactg gcgaaacctt gattggcgct agcgtgaagg tggctggtac aaccaacggt
     5761 gccgttaccg atatagatgg taactttacg ttgaactgca agcctggagt aacgctcgaa
     5821 gtgagctaca tcggttacaa gacgatgacc gtgaaagctg ctaatggcat gaaaatcacg
     5881 atgcaagagg atggtaaggc cttgaatgag gtcgttgtta ccgcccttgg tatcaagcgc
     5941 gaccgcaagg ctttgggcta tggcttggag gaggttaaag gtgaggaact taccaaggcg
     6001 aaggaaacca acgtcatcaa ctctctttca ggtaaggtgg ctggtctcgt tgtgcagaac
     6061 accgctggcg gtgcttctgg ttctacccgc gtgcttcttc gtggtaatac agaaatgtca
     6121 ggcaataacc agcctctcta cgtggtggat ggtgtgcctt tggataatac caactttggc
     6181 agtgctggtg aagctggtgg ttatgacctc ggtgatggta tctctgccat caatcctgac
     6241 gacatcgaga cgatgaccgt attgaaaggt cctgctgcct ctgccctcta tggtagccgt
     6301 gcttcccacg gtgttatctt gattacgacc aagaaggcgg agaaggataa ggtggctgta
     6361 gaatataatg gctctttcac catcgatacc cagttggcta agtggaacga catccaggaa
     6421 gtgtatggta tgggatatgg tggcaagttg cctacttcta gtacttctgg aaccaactcc
     6481 agttggggac ctaaggcgga tgactttgtt tataagtatt ttgatggtca ggagcatgct
     6541 ttcatgatgt atcctaataa tgcctctgat ttcttccgca ctggtttgac cgctcagaac
     6601 tcagccatcc tctctgttaa ctctggtaag actggtatgc gtttctcttt cacagatatg
     6661 cgcaacaagg acattctgcc taacaccaac atgagtcgtg acaacttcaa cctgcgtgtc
     6721 aacacatcag ctggtcctgt ggatttcgac ttcactgcca actatacccg tgaggatgta
     6781 aagaaccgtc ctgccttggg tgattctcag agcaatgtag gtaagaacct catgactttg
     6841 gctggtacat acaaccaggt atggctcaag aactatgagg atgccgatgg caactaccag
     6901 aactggaatg gtaacgacca gtataacaag aacccatatt gggatctcta taagaacagc
     6961 aatacatcta agaaggatgt gttccgcttg acaggtaaag ctatctggaa catcgacaag
     7021 cacttgaagt tgcagggtac catcggtacc gacatcacca atatgaactt cgaggacttc
     7081 atcgccaaga ccactcctgg tacacctgca ggaaagctta ccgaccaaat cttcaataac
     7141 cgcacactga atgcggagct cctcgccctc tacaacaatt catggggcga cttcgatgtc
     7201 aatgccacag ctggtggtaa catcttcaag gtgaacaaca agaccatcac caacaccggt
     7261 ctcaaccagc agatgaatgg catcaagaac atcatgaact atcaggagca gaacactcgt
     7321 gagagcatgt acaagaagca gattagctct ctctatgcca gcgcaagcat cggctacaag
     7381 catacttact atctggaggg aaccatccgt ggcgataagt catctacgct ccctaccagc
     7441 aataatacat acgtttaccc atctgtatca ggtagcttgg tattctctga gttcatcaag
     7501 aacaagaaga ttatcaacta tggtaaggta cgtgcatctt gggctaaggt aggtagcgat
     7561 accgaccctt atcagcttgc actcaactac tccacaggca agtacagcta tgctggctat
     7621 accatcggta tgattagcaa tgctacccag ccaaacaagg acttgaagcc aaccatgaca
     7681 ggctcttatg agttgggttt ggagatgaag ttcttcaatg gtcgcttggg cttggatgcc
     7741 acctattata atcagaactc caaggaccag atcttgagcc ttgcctctac cactacttct
     7801 ggctactctt accgcttggt aaatgccggt gagattcaga ataagggtat cgagattgcc
     7861 ctcaatggtc gtctgctcca gatcaaggac ttcggttggg acatgggtgt caacttctcc
     7921 aagaatacca acaaggtgaa gtcgcttgta gatggcatgg actatttcga gttggctaaa
     7981 gctacctggt gcggcgtatc tgtaggtgcc gaggtaggag agaattatgg tgctatccgt
     8041 ggtaaggact tcaagcgcac tgctgatgga caggtgatta tcaatccaac aagcggtttg
     8101 ccagaggttg accaaacagt gaagaccatc ggtaactctt cttgggattg gacaggtggt
     8161 ttctatacca cattctctta caagaacttc cgactctctg catccttcga tgtgaaggtg
     8221 ggtgccgaca tctattctat gtctatgaac tctgcttata agactggtaa ggcaaagcag
     8281 accttggctg gtcgtgatga gtggtatgct tctgaggaag ctcgtgaggc tgctggtatg
     8341 acagatgagc agtggcgtgc tgctggcaat gccaagggct ttgtggctcc aggtgtcatc
     8401 gacaatggtg atggaactta tcgtccaaac gatatcgcag tcaacccaga gacttattgg
     8461 aaggctattg ccaacaatgt gcagagtgcc tttgtatatg acaactctta cgtgaagtgt
     8521 cgtgagatta ccttcggtta tactttccct gagagtttgt tgggcaagtg ggtcaagggc
     8581 ttgaatgttt ccttcgtggc acgtaaccca ttcattgttt ggaagaacat tcctaacatc
     8641 gacccagact caagttataa tacttctgga ctcggtttgg agtatggttc tttgccatct
     8701 cgcaagagct atggtatcaa cgtgaatgtg aagttctaac tttattttaa aagacaagaa
     8761 aaaatgaaca atataatcaa gaaatatata ggcaaaggcg gtttcgccat ggctatgctg
     8821 ttgatggcta ctggcggtgt gatgacttct tgctcagacg atatgatgga gcgcaccaac
     8881 accgataaga ccaaggtgaa ccagctggac cctaatgcgc agttgacaac atctttgttg
     8941 cagacttatg gtgactttag tttgatggat acctatcgta actatatcac tggtttcact
     9001 cagcattttg ctggtggttg gaatgtgacc aattacgcag gtgccgtaca tcatgaggat
     9061 gatattgccc gccgtatctg ggaccgttat tatgaggtgg ctatcaagaa tctcgtagat
     9121 gccatccaca aatctgagga caaggctaac ctgaatgctg ccctccgcat ccatcgtgtc
     9181 tatctacttt ctgtattggc agatacttat ggtgacattc ctgcttcaga ggcaggtttg
     9241 ggttacatct caggtatttc caatcctaag tatgataccg tagaggactt gtatggttgg
     9301 ttcttcaccg agttggatgc ttgcgagcaa cagttgggta ctggtaccga ccatatctct
     9361 ggcgatgtta ccagcatggg tggtgatgtg gctaaatgga aaaaatatgc caactctctg
     9421 cgtatgcgtt atgcgatgcg tatctctgat gtaaatccaa gcaagggcca ggaagagttt
     9481 gagaaggcga tgaaccatgc cgatggctat attgcatcag ctgctgacga tgcttatatc
     9541 aagtatgctg attcacctta tacctattat gatggtgcca acgactacga cttccgtacc
     9601 aatgccttgg gcgagattct ctatggtcag gatccatcgt cgccaacttt cgtcagctcg
     9661 acattgttct atcagttgca gaatacaggc gaccctcgtc tctatcgcat ctgtcgtcac
     9721 tactacaata tcaagcgtag ccaggtgaag cctgacaagg agcagaacat cgaccttacc
     9781 gatgaggtgt tggcttattt ccagcgcaac aatatcggtg aggaaccatg taatacaggt
     9841 tcggcgtggt atgagaactg gatgaatgta gctgatgctg ctgagttccc taccttggca
     9901 aaacttgctg agcaggatgc caacagttat gacaactccg actatcgtgc ccgcttgatg
     9961 cgtccttgct tgaacatcga tttcgagatg ccttcatgcc ctggtatcct catcacttct
    10021 gccgaggtgg atttcctttt ggctgaggct aagaccaagg gatggaacgt aagcggtgat
    10081 gccgagagcc attacgaggc tggtgtgcgt gcttccatgg agatgctcaa caattattat
    10141 cttacatcca ataagatttc tgaggatgaa atcaatgcgt ttatcgccaa caatcagttg
    10201 ggcgaaaatc caaagcaaac catcaacaca caggcttgga ttctccacat gatgaaccca
    10261 tctgaggctt gggcgaacat gcgtcgctcc gactatcctg ccttgttgga tcgcagtcgt
    10321 ttggcgacat tccctggtga tggtttcgta tatgacgacc ctaatatgtc aatgcctact
    10381 cgcttgcgct atcctgagtt ggaaggtcag tacaacagtg tgaactataa ggctgccatc
    10441 gagcgcatgg gtggtactga tgactggcac aagaagttgt ggtgggataa gtcggatgtc
    10501 aacgtacagg gcgacttcaa tcctccttac ggcaagggct acattaagta attaagaatt
    10561 aataattaag aattaataat taggggctga cgcctttatg aataaatatt attaagatga
    10621 aaaagataat gaatcaatat atgggtaagg tgttgaagtc atggatgatg cttttcgcca
    10681 ttagcttcgc actcgcaggc actgctacac tgtcttcttg ttcctctgac gacgatcctt
    10741 tcttcaccgt atcagaagat gacgatcctc gtatcttgaa caccgacttg gctgaccaga
    10801 agttggatcg caagaccaaa ttgaacttgg aaattaaagt cactcctgtt cactacacca
    10861 ctgtgacatg gctcttggat gatactcaga ttgctgaggg tacaaccatc gaccagactt
    10921 tgccagtggg caatcatact ttgaagattg tggcaaccac caccaagggc aagagcacat
    10981 cccgcacctt gaaagttacc gtgactcctg ctgccgatga tccagccctg ggtaccaatg
    11041 ccatcgagct ttgggtagct ccaggtgctg agaccactat ccataagtgc aagaatctcg
    11101 gtacagtaac taaagtaatg gtaggtggca aggaagtagt cttcgaggtt ctcgaagagg
    11161 gcacagcctt gaagctcaca gctcctacag gtttggagaa tggtgactat gatatcactt
    11221 tggtagatgg tgagggcaac cagttctctg gcggaatcat caaggtaacc accgaggctc
    11281 gcccatctat ggagaatacc ctctgggaag gtgagttctc tgtaacatgg ggcactcctt
    11341 tcgaggcctt gaaggatacc ttcctctcaa aggtgaaggc gggtactatc ctccgtgttt
    11401 atgtggatgg aaatggccag ggtaccgcta ccacagcttg gtggaacaac atccttactg
    11461 gtaagggcga ccctgatcgt aatgacttca tggtgactgg tcctgctaca tgggagtttg
    11521 aactgaccga cctctctatc caactcttga cagagcagaa tggtttcctc ctcgtgggtg
    11581 atggttacac cgtaaagaaa gtaactattg aataacatat tagaaagatt tccgttttta
    11641 tcataaaacg tcaaaccttt actgtttatg aagaaaattt tattatctat ttcattgttg
    11701 gcattggctt atacagccag tgccaatgtt ccggttatca agagcgaccc taagattgag
    11761 gctcaggtag aacaaaccct gaagaaactc accttggagg aaaagatagg tcagatgatg
    11821 gaattggtga ccgacctctt tggtgccaac gacaagaacg gtgtgttcta tatcgacgag
    11881 cacaagaccg attctatcct ttcccgctat aagattggct ctatcctcaa cgctccaaat
    11941 acctgcgcac caaccgccaa gcagtgggag aagtacattg cgcaaatcca gaagatctcg
    12001 atgaagcgca tcggcatccc ttgtgtcttc ggtctcgacc agaaccacgg ttctacttat
    12061 acacagggcg gaaccctctt cccgcagaac atcaatgtgg ctgccacctt caatcgtgag
    12121 attgctcgcc gttcggctga ggctaccgct tatgagactc gtgcggtgag cataccttgg
    12181 acttacagtc ctaccgttga tctcggtcgt gatgcccgtt ggcctcgcat ctgggagaac
    12241 tttggcgagg attgctacct cagttctgag atgggcaagg cgatggtcta tggtttccag
    12301 ggcgaggacc caaacaacat cgaccagtat cacattgcca cttcaatgaa gcacttcatg
    12361 ggctatggtg tgccttggac cggtaaagac cgtacgccag cctatatctc tccagccgac
    12421 ttgcgagaga agcacttcgc tcctttcctg gcgggtctgc aggctggagc cttaaccgtg
    12481 atggtgaatt ccgcttccgt caatggtatg ccgatgcatg ccaacaagga catcctgaca
    12541 ggatggctga aggaagagac aggatgggat ggtgtgctca tcaccgactg ggcagacatc
    12601 aacaatctct atactcgtga gatggtggca aaggacaaga aggatgcgct ccgcatcgcc
    12661 atcaatgccg gtatcgatat gattatggaa ccttattctt gcgatgcttg tggttatctt
    12721 gtagaactgg tgaaggaagg taagattccg ctgagtcgca tcgacgatgc ctgtcgccgt
    12781 gtgcttcgca tgaagtaccg tctcgacctc ttcaagaacc caacccagaa actgaagaat
    12841 tatcctaagt ttggtggtga ggagtttgcc aagctcgcct tggagggagc taccgagagt
    12901 atggtgctcc tgaagaacga gggtaatatc cttcctttgc agcatggcaa gaagattctc
    12961 cttacaggtc ctaatgccaa tcagatgcgt tgcctggatg gtggatggag ctatacctgg
    13021 caggggcatc gtgccgatga gtttgccggc aagtacaata ccatctatga ggcattctgt
    13081 aatgagtatg gcaaggagaa tgttatcttg aaccagggtg ttacctataa tgagaaggga
    13141 aaatactggg aggagaacga acctcaaatt cagggggcag tggctgcagc gaaggatgcc
    13201 gacgtcatcg tggcttgcat tggcgagaac tcctatacag agactccggg caacctgacc
    13261 gacctttggc tctcagagaa ccagcgtaat ctggtcaagg ctttggctca gacaggcaag
    13321 cctgtcatct tggtgctgaa tgaaggtcgt cctcgtctca tcgctgacat cgaaccattg
    13381 gcacagggca tcatcaacat ccttatccct ggcaacatgg gcggcgatgc tttggcaaac
    13441 ctggtatcgg gcaagtcaaa cttcagtggc aagatgcctt acacctatcc taaggaaatc
    13501 aattcgctcg tcaactatga cttcaagaag agtgaggagg tgggtacgat ggaaggtgct
    13561 tacgactaca atgcgaagat tacccagcag tggggcttcg gatatggttt gagttatacc
    13621 acttacaaat atagcaacct gaaggtttct cagtctgatt tccgccacgg cgacatcatc
    13681 aaggtgagcg tggatgtgaa gaatacggga aaggtggcag gcaaggagag tgtcctcctg
    13741 ttcagtagcg atctcatcgc tagtatggtg cctgatggcc gtcgtctccg tgccttcgac
    13801 aaggtggaac ttcagcctgg tgagaccaag accatgacat ttgaattaaa ggcagacgat
    13861 ttggccttcg taggttggaa tggcaaatgg agattggagg aaggcgactt caaattgatg
    13921 attgccgacc agagtgccga tatccattgc actgatactt atcagtggtc tactgccaac
    13981 cgataatgta tatttaaaag atgatttaaa gaaaagagcg tgccaagagt ggtgcgctct
    14041 ttttgtttgc atagtaaaat gcagaagagt taaatatcta caagaatccc ccatgatgtt
    14101 tggtggtatg tcttgaaatg attacttttg caaatcataa tttttgcaga tttacagaat
    14161 cattcaaaac aaggataaat ggaaatagta attggaatca tcatagggct tgccatcgga
    14221 ttcttcgtgg ggaaactgat ggaagcaaaa agtgcgggag aggagaaaac ccagctcgta
    14281 gcgaaggctc aggtgctggc ggctaacatc gaacagataa aactgcatca tgcttctgag
    14341 gttcaatcaa tgaaatctca aatggagaac gagcggctgt atgcggcgaa actcagggcg
    14401 gaaagcgacc agcagtgggc acagaaactc gagagtctga agcaggaaat gcagcgaatg
    14461 acgatagaac agcagaaggt ggcagctgag cagttggctg ccaagcagtc ggctctgcag
    14521 gaaaacaacc gtctgcagat ggatgaactc ctgaaaccta tcaaggaaca gtttgctgat
    14581 ttcaagaaat cggtagagga gagcaaaacc cagaacgagg tgaacaagaa ggaactgcag
    14641 aacaccttcg aggcaacgat gaaactcttc cagcaggaac agcagcaggc tgttctgaac
    14701 ctgaaggagc agaccgagaa gattggctcc gatgctgcca acctgaccaa ggcattgaag
    14761 ggcgacagca agatgcaggg cgactggggc gagatggtgc tggaaaccat cctggagaac
    14821 agcggacttc gtaaaaatga ggaattcttc attcaggagt atacgaaaga tgaagaggga
    14881 aagaactatc gtccggatgt catcgtccga ttcccggaag gcagaagtgt ggtcatcgat
    14941 tccaaggttt cgcttaccgc ctattccgat gctctggcag ctgaagatga ggctgaacag
    15001 gaacgcctga tgaaggcgca tgcgctgagc gtacgaaagc acatcgatga actggcagcc
    15061 aaagactatt ccaaactggt ggatgatgcc atcggcttcg tactgatgtt catccctaac
    15121 gaaaccagct atatcgcagc gatgaagcag cagcctgatc tcagccgtta tgcttatcag
    15181 aagaagatta tcatcatctc accaagcaat ctgctcatgg cgttgcagct tgcctataat
    15241 ctctggcagt acgaccggca gaacaagaat gtggagaaaa tcgtgaagac ggctgctgac
    15301 ttgtatgata aggtagcagg cttcgaagat acctttatga gtgtgggtga tctgataacc
    15361 cgcctttcgg gtacttttga taaggctaag aagcaactct atgacggcac cggcaatgtg
    15421 atgagaaggg tagagagcct gaagggactt ggagtaacac cgaaaaagca gatcaaggaa
    15481 ctggataatc tgtaaagtgt atacaaatag tctactaccg gtaaaaaggg aaacggggcg
    15541 aaaagtattt ttttagttac cgtaacattt ctaattgttc aatttaagtt tctaattgtt
    15601 caatattttg aaataatctc taaaaaggag cggtatttca gattaaattc gtaattttgc
    15661 cccgactcaa cagaaaagaa atcattgtat tgattataaa aaggtaaaaa tttacataaa
    15721 acaacatcaa taattattaa tcatgaaact gaacgaaatt ctttcagaca gctttaatgc
    15781 tgcagaatgg gaagctaagg gttatgagct tcctaagtat gacatcgcag ccgtagctaa
    15841 gaagactcac gacgagccta cttgggttca ctttggtgca ggtaacatct tccgtgcgtt
    15901 cccggcagcc atccttaacg atgcacttaa caccggcaag tacgatcgtg gtgttattgt
    15961 tgctgaaagc ttcgactacg aaattatcga caaggcttat cgcccttaca ataatctctc
    16021 tcttctcgta agcctccaga gcaacggaac catcgagaag aaggtcatcg cttctatcac
    16081 agaaagcctc aaggcggata aacagtttgg tgaggactgg gcgcgtctgg tccagatttt
    16141 ccaggctcca agtctgcaga tggtaacttt caccatcaca gagaagggat attcttataa
    16201 tgatgccgat ttgtcacgtg gtcttgatgc tgtatttgct atgggtaagc ttaccgctct
    16261 tctctatgag cgttataagg caggcaagtt gccacttact cttcagtcta ccgacaactg
    16321 ttctcacaat ggcgaccatg ttaaggctgg cgtaaaggct tatgctgagc gttgggcaca
    16381 ggctggtatc gtagaggctg gtttcgtaga ttatatcaat gacagcagca agattaccta
    16441 tccttggtct atgattgata agattactcc tcgtccacac gagaaggtac aggcgatgct
    16501 cgctgaggat ggtttcgagg ataacaatac gattatcacc gagaagcata ccttcaccgc
    16561 tcctttcgta aatgctgagg aagtgcagta tcttgtttgc gaggatactt ataccaacgg
    16621 tcgtccgcca ttggagttgg gcggtgcgct ctataccact cgcaagaccg tggatgaggt
    16681 tgagaccatg aaggtaacca cctgtctgaa ccctctccat acagcgatgt ctatctatgg
    16741 ctgcatgctc gactatacct tgatttctgc cgagatggct gatgaggacc ttcgtgcctt
    16801 catccagaag atcggttaca tcgaggcgat gccagtggtt acagatccag gtgtattgaa
    16861 cccatacgag tttatcggca ccgttatcaa caagcgtctg cctaacccgt tcatgccaga
    16921 tgctcctcag cgcatcgcta ccgataccag tcagaagctc tctatccgtt tcggtgagac
    16981 catcaagaag tatatcgacc gtggtctcga caagagcaat ctcgtgttga ttcctttggt
    17041 attggcaggt tatgcccgtt atctcaaggc attggatgat aacctgaagc cattcgagcc
    17101 atcttctgac ccattgttgg ctgagcttca ggctatcgta gctcctctgg aggtaggcaa
    17161 ggctgatcag gactattctt gcctgaagaa cctctattcc cgcaaggatg tattcggtct
    17221 cgatctctac gaggctggct tcggtgagca gattgagggc atggtgaagg aactcttcgc
    17281 cggcaagggt gctgtaagag cgacattgca taaatatgtt tctgcaagat aattcatttt
    17341 taaacttata cattataata tatatatgga aagaacatgg cgctggtttg gcaagaaaga
    17401 taagattaca cttgcacagt tgaagcagat tggtgttgag ggcattgtta ccgcattgca
    17461 cgatgttcct ctgggcgagg tttggacacg cgagaagatt catgaactca aggagtacat
    17521 cgagtcttat ggtatgaaat ggagcgtggt agagtctttg cctgtggttg aaaccctgaa
    17581 atatggcggt ccagaccgtg accatcagat tgaggtttac aaggaaagtc tccgtaacct
    17641 gggcgaggaa ggcatcaagt gcatctgcta caactttatg ccagtcttgg actgggctcg
    17701 taccgatttg tctcacgaca atcctaacgg agccaacaac ctctatatga actggggcga
    17761 gtttgcctac ttcgatatct atatcctgca gcgtgaaggc gctcgtgagg attgggctga
    17821 gttctctaag gagcacaagt ggggcagaga cctcgtggct gaggctgatg aaatcaagaa
    17881 gacttctaca ccagagcagg atcatgcctt ggtagagaat atcatcatca agacccaggg
    17941 tttcgtatcg ggtaacttca gcgagggcga ttctgctcct gttcagaagt tccgcgacct
    18001 cttgaagctt tatgatggca tcgacaagaa gaagttgcag gagaacatga agtattggct
    18061 ggaggctatc atgcctatct gcgatgagta cgatatcaac atgtgtgttc acccagacga
    18121 tcctccttat cctgtattcg gtttgccaag aatcatcggt cgtgccgagg atatccagtg
    18181 gatgttggat gcagtgccaa acaagcacaa tggtttgact ttctgtgcag gttcattctc
    18241 tgccggcgag cacaacgact gtgtggcaat ggctaagcag tttgccgacc gcactcattt
    18301 tgttcatctg cgttcctgct acattttccc taacggcaac tttacagagg cttctcactt
    18361 gggtggtcgc ggccatctga tagaactttg ccgcatcttc gagaaggctg agcaggaagg
    18421 caagtgcaat tccggtcgtc gtttgcctat gcgagtagac cacggtatga ccttcactga
    18481 tgagccgggt ggcgtattcg atgagagcaa tcatggtcac aatgccggtt acactctcct
    18541 tggccgtatg tttgccatgg gtcagattca gggtgtcatc gcaacagtag atgatgaact
    18601 gggcattgag tataagcagc cgggattcta tgattagttg atagtttata ggctattaag
    18661 tgatttgaaa ttcaggttag ataaaatacg aaaaaggcta gcgtgcgttt ttgcatgcta
    18721 gcctttttgt gctgattttt ttggttattg gctaaagcac cacctcctct acatacttca
    18781 ccagcgaatc cttgccgtta tgcagataga agtctacacg aaccacgtgg ttgatgtcgg
    18841 cattgccctt cacctttatg tgtcgggtct tgctgtacat catcgtgtcg cggcgtgaag
    18901 gataggatac gagctcgatg aggtctttgg tagaattgct gcccacataa tagatgccta
    18961 cactgtcttt tccgttcttg atggctgcaa tcttcgccat cttcttggca tgagccgcag
    19021 aggtatctat cgggtaaaac tcgctggcag ctaccgtgtc gccgtcatgc tggtcgggtg
    19081 caaacttgca gctggtaccc atcgtagtga taaaggatgc agcagccagg gctgccacaa
    19141 agtataatat tttcttcatt gttatttcct ttcttttctt taaagaatcc tgttttgttc
    19201 gcaaaatgcg ttatcggctg caaaagtaca aaaaataact cgaaaagcca tacctttttt
    19261 atctttttcc ttttaatact tcggatggag agacgcgtgc tgagttgggc ggaaggagtt
    19321 gtggggatgg catggaagga gcgctatgga aggagttgga aggtatggat gatatggatg
    19381 gaattccgtg caaagataca acttttctct gatactgcaa aaattggggg tgtgataagg
    19441 aaatgtttga actatgcttt cagattgaaa gtagttaaac ttccttactc atagttttgc
    19501 aggtgacaac tcatagtttt acgggtagca actcatagct ttgttctctt aaagtataga
    19561 gttaagcagt aaatcaggtg tttatgaggg ttgtgatgtt tttacagcaa tgactcagtt
    19621 cctcagtttt tctctgaccc ttcacttttt cctttattta gaagtttatt atatatataa
    19681 tatataacaa tttaaaacaa ctttgaacta taagggctat atacccctag aaaaaaactg
    19741 aggaactgag gaactgagtc aatgatagag acttagaatc ttactcttga tactgttgaa
    19801 taggtgctta tgttaaaatt taagtatcag attatcagat aaataaaata cttgaccccc
    19861 tgaaataagg ggtcaagtgt ttattgtgat acccatacgt cgtgaaacac aacgtatggg
    19921 tatgaaaaag aatttcgtta cattgaactt tcaaatcgta acttgatgag atttggctga
    19981 tttacatctc aaccactact tcatgcttgc cttgagagca aggaatgatg gtgcctgaga
    20041 taggagtgcc atccactgta atctgcttca cacccttctg gtttccgcta ggattcttta
    20101 ctgtgatatg gtattcgcca ccacggaact tgcgggttac ctcatactcc ttagcggtac
    20161 ttgggagaca aggatcgatg agcaaacctt cataatctgg cttgatgccg aggatgaatt
    20221 ctgatacagt ataccacatc catgccgctg taccggtgag ccaggagttc tttccttcgc
    20281 ccggtttggc tgcatcctta ccggctacca tctggcagtt tacgtaaggc tctaccttgt
    20341 gaagtgtctg atatttttcc tctacatagc taggcagaat cttggtataa tggctccagg
    20401 catcgttgcc tcgaccggct acagtctctc cgatgatgac ccaaggattg ttgtggcaga
    20461 agataccggc gttctccttg tagccttcag gataagaaga aatctcaccc atttctacat
    20521 gataggtagt gtaggctgga ttgttcagca ccagtccgtg ctcgcattcc agtcgtttct
    20581 tactgctgtc cagtgctata tcgcagagtc cttcttccag accgatacca gccatcgtac
    20641 accagccctg gctctcgatg aagattttgc cttcctcgtt ctcatcacta ccaatcttgt
    20701 tgccgaagaa atcgtaagcg cggaggaacc attcaccatc ccatccatgc tgctttacag
    20761 cctcgttcat ctcatctaca gcctgctgca tgcgctcagc ttctgtcaaa taatcttcct
    20821 ctgcaagacc ggctatttcg ccctccttgc tttccatagc ttccttggca agctgcttgc
    20881 acagagccac ataatccttg ccggtaacaa cgaacagacc ggctatcatc agactctctg
    20941 ccttgcttcc ttcgcccttg ttttcggtgg tctggaaact ctcgttaggg tcccaggaga
    21001 agcagtttag gttcagacag tcgttccagt cggctcttcc gatgagtggc aacttgtgcg
    21061 gacccaggtt gttgataaca tggttcatcg aaatcttgag gtgctcgaag aggcttactt
    21121 ctgtgcctgg ctggttgtcg aaaggcacct gctcagcgag gatagagaag tcgcccgtct
    21181 ccttgatata ggctacggta ccgaagatga gccagcaagg gtcgtcgttg aaaccgccac
    21241 cgatatcgtt gttgccacgt ttggtgagtg gctgatactg gtggtagcag ccaccgtcag
    21301 ggaactgggt gctggcgata tcgatgatgc gctggcgggc acgggtaggt atctgatgaa
    21361 cgaaacctac gaggtcctgg ttggaatcgc ggaagcccat gcctcgaccg atgccgctct
    21421 cgaagaaact tgccgaacgc gacatacaga aggtgatcat gcactgatac tggttccaga
    21481 tgttcaccat gcggtctaac ttgtcgttgc cgctcttcac ggtgaagatg ttcagtaggt
    21541 tatcccagta ctggttgagt tctgcgaagg cagcatccac cttttctgtg gtatcaaact
    21601 tggcgataag ctgatgagcc ttctccttgt tgattacctt cttggcgctg aacttcttgt
    21661 cctgttcgtt ctccacatag cccagcagga agatgaggtc gcggctctcg cctggctgca
    21721 gggtaacctc gatataatga gatgcgatag ggctccagcc gtgggcaaag ctgttgcgtg
    21781 gcttgccttc catcacagcc tcaggctcgg caaactcgtt gtagagtccg atgaagctct
    21841 cgcggtcggt atcgtagccc tgaatctcgg tattcactgt atagaaagca tagtggttgc
    21901 ggcgctcgcg gtattcggtc ttgtgataga tagtagaacc ctctacctcc acctcgcccg
    21961 ttgagaagtt gcgctggaag ttctccatgt cggtagcagc attccagagg caccactctg
    22021 caaaggagaa caccttgagg gtcttctcct cctcagtctg gttcttcagc gtcatcttct
    22081 gcacctcagc ccatgtatgg agcggaacga agaagagcac actcgcctcc acgccgttct
    22141 tgctgcccgt gatgcgggta tagttcatgc cgtggcggca ttcgtagctg tcgagcggtg
    22201 tcttgcaagg tttccatccc gggttccata cggtatcgcc atctttgata tagaaatagc
    22261 gaccgccatt atccattggc acaccattgt agcgataacg ggtgatgcga cggaacttgg
    22321 catccttgta gaaggaataa ccacctgctg tgtttgagat gagcgagaag aaatcctcat
    22381 tacccaaata attgatccaa ggccatgggg tctttgggtc agtaatcacg tattcgcgat
    22441 tggcgtcatc aaaatgacca tacttttttt ctgccat
//
