LOCUS       NZ_CP012938            20045 bp    DNA     linear   CON 08-JAN-2025
DEFINITION  Bacteroides ovatus strain ATCC 8483 chromosome, complete genome.
ACCESSION   NZ_CP012938 REGION: 2036824..2056868
VERSION     NZ_CP012938.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN03852683
            Assembly: GCF_001314995.1
KEYWORDS    RefSeq.
SOURCE      Bacteroides ovatus
  ORGANISM  Bacteroides ovatus
            Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
            Bacteroidaceae; Bacteroides.
REFERENCE   1  (bases 1 to 20045)
  AUTHORS   Wu,M., McNulty,N.P., Rodionov,D.A., Khoroshkin,M.S., Griffin,N.W.,
            Cheng,J., Latreille,P., Kerstetter,R.A., Terrapon,N., Henrissat,B.,
            Osterman,A.L. and Gordon,J.I.
  TITLE     Genetic determinants of in vivo fitness and diet responsiveness in
            multiple human gut Bacteroides
  JOURNAL   Science 350 (6256), aac5992 (2015)
   PUBMED   26430127
REFERENCE   2  (bases 1 to 20045)
  AUTHORS   Wu,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (13-OCT-2015) Center for Genome Sciences and Systems
            Biology, Washington University School of Medicine, 4444 Forest Park
            Ave., Saint Louis, MO 63108, USA
COMMENT     REFSEQ INFORMATION: The reference sequence is identical to
            CP012938.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method       :: HGAP 2.0 and Celera v. AUG-2014
            Genome Coverage       :: 350X
            Sequencing Technology :: PacBio; Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001314995.1-RS_2025_01_08
            Annotation Date                   :: 01/08/2025 18:05:31
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,927
            CDSs (total)                      :: 4,834
            Genes (coding)                    :: 4,763
            CDSs (with protein)               :: 4,763
            Genes (RNA)                       :: 93
            rRNAs                             :: 5, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 5, 5, 5 (5S, 16S, 23S)
            tRNAs                             :: 76
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 14 of 71
            Pseudo Genes (incomplete)         :: 53 of 71
            Pseudo Genes (internal stop)      :: 11 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..20045
                     /organism="Bacteroides ovatus"
                     /mol_type="genomic DNA"
                     /strain="ATCC 8483"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /culture_collection="ATCC:8483"
                     /type_material="type strain of Bacteroides ovatus"
                     /db_xref="taxon:28116"
                     /geo_loc_name="USA:Woods Hole"
                     /collection_date="2009-10-11"
     gene            complement(1..1176)
                     /locus_tag="Bovatus_RS08285"
                     /old_locus_tag="Bovatus_01697"
                     /db_xref="GeneID:29451450"
     CDS             complement(1..1176)
                     /locus_tag="Bovatus_RS08285"
                     /old_locus_tag="Bovatus_01697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008026078.1"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0008381 - mechanosensitive monoatomic ion
                     channel activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="WP_004311434.1"
                     /db_xref="GeneID:29451450"
                     /translation="MLVVDLGKWMNKTLINWGIDPAVADRFDETIMALLMIVVAIVLN
                     YLCQAILIGGMKQYTRRKPHQWNTLLMKRRVFHNLIHTIPAFLVYSLLPMAFIRGKEL
                     LLISQKACVIYIIFSLLLAINGILLMIMDIYDGRESMKDRPMKGFIQVLQVLLFFVGG
                     IVIIAIIVNKSPATLFAGLGASAAILMLVFKDSILGFVAGIQLSANDMVRPGDWVTLP
                     SGDANGIVQEITLNTVKIQNFDNTISTIPPYTLVSSPFQNWRGMTQSGGRRVMKSITL
                     DLTTLQFCTPEMLDRYRKEIPLMADYQPEEGVVPTNSQVYRVYIERYLCSLPVVNQEL
                     DLIISQKEATMYGVPIQVYFFSRNKVWKEYERIQSDIFDHLLAMVPKFDLKVYQYSD"
     gene            complement(1319..3136)
                     /locus_tag="Bovatus_RS08290"
                     /old_locus_tag="Bovatus_01698"
                     /db_xref="GeneID:29451449"
     CDS             complement(1319..3136)
                     /locus_tag="Bovatus_RS08290"
                     /old_locus_tag="Bovatus_01698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004304358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-fucosidase"
                     /protein_id="WP_004300809.1"
                     /db_xref="GeneID:29451449"
                     /translation="MNKLLTSLLLSVTLMSGAQAQKKENYYVKHVEFPQSATIEQKVD
                     MAARLVPTPQQYAWQQMELTAFLHFGINTFTGREWGDGKEDPALFNPSELDAEQWVRT
                     LKEAGFKMVLLTAKHHDGFCLWPTATTKHSVASSPWKNGQGDVVKELRAACDKYDMKF
                     GVYLSPWDRNAECYGDSPRYNDFFIRQLTELLTNYGEVHEVWFDGANGEGPNGKKQVY
                     DWDAFYQTIQRLQPKAVMAIMGDDVRWVGNEKGVGRETEWNATVLTPGIYARSQENNK
                     RLGVFSKAEDLGSRKILEKATELFWYPSEVDVSIRPGWFYHAEEDGKVKSLKHLSDIY
                     FQSVGYNSVLLLNIPPDRRGLIHEADIKRLKEFADYRQQTFADNRVKNGRKYWSTTSG
                     GEAVYALKSKSEINLVMLQEDITKGQRVEAFTVEALTDNGWKEVGKGTTIGYKRMLRF
                     PAVNANKLRVRIDECRLTAYVSQVAAYYAEPLQEETTKEDWNNLPRSGWKQVAASPLT
                     IDLGKTVTLSSFTYAPSKAEVKPTMAFRYQFFVSMDGKSWKEVPASGEFSNIMHNPLP
                     QTVAFSQKVQARFIKLEATTPDATVAKVNMNEIGVMVIP"
     gene            complement(3281..6367)
                     /locus_tag="Bovatus_RS08295"
                     /old_locus_tag="Bovatus_01699"
                     /db_xref="GeneID:29451448"
     CDS             complement(3281..6367)
                     /locus_tag="Bovatus_RS08295"
                     /old_locus_tag="Bovatus_01699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008026074.1"
                     /GO_function="GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 2 TIM barrel-domain
                     containing protein"
                     /protein_id="WP_004300810.1"
                     /db_xref="GeneID:29451448"
                     /translation="MLMNISLKKRTLLVLLSGLTATFTLAQQQPLPEWQSQYAVGLNK
                     LAPHTYVWPYANASDIEKPGGYEQSPFYMSLNGKWKFHWVKNPDNRPKDFYQPSYYTG
                     GWADINVPGNWERQGYGTAIYVNETYEFDDKMFNFKKNPPLVPYAENEVGSYRRTFKV
                     PADWKGRRVVLCCEGVISFYYVWVNGKLLGYNQGSKTAAEWDITDVLNEGENVVALEV
                     YRWSSGAYLECQDMWRLSGIERDVYLYSTPKQYIADYKLNASLEKEKYKDGIFGLEVT
                     VEGHSAISGATSIAYTLKDADGKTVLQDAIRIKSRGLSNFITFDEKNIPDVKAWSAEH
                     PHLYTLILELKDEQGKVTELTGCEVGFRTSEIKDGRFCINGVPVLVKGTNRHEHSQLG
                     RTVSKELMELDIKLMKQHNINMVRNSHYPTHPYWYQLCDRYGLYMIDEANIESHGMGY
                     GPASLAKDSTWLTAHMDRTHRMYERSKNHPAIVIWSLGNEAGNGINFERTYDWLKSVE
                     KTRPVQYERAELNYNTDIYCRMYRSVDDIKAYVKEKDIYRPFILCEYLHAMGNSCGGL
                     KEYWDVFENNPMAQGGCVWDWVDQSFREIDKNGKWYWTYGGDYGPEGIPSFGNFCCNG
                     LVGANREPHPHLLEVKKVYQNIKVTLANQKNLTIRVKNWYDFSNLNEYVLNWNVTADN
                     GKILAEGTKTVDCAPHATVDVTLGAVKLPNTVREAYLNISWTRREASSMIDKDWEVAY
                     DQFVFAGNKNYTGYRPQKAGETTFTVDKQTGALTSLNLNGKELLATPLTLSLYRPATD
                     NDNRDKNGARLWRDAGLDCLTQKVVSLKESKTSTTARVEILNAKTQRVGIADFVYSLD
                     RNGALKVHTTFQPDTTIVKSMARLGLTFRVSNAYDQVSYLGRGDNETYIDRNQSGKIG
                     VYQTTPERMFHYYVAPQSTSNRTDVRWVKLADTSGEGIFVESDRAFQFSIIPFSDVLL
                     EKARHINELERDGLLTVHLDAEQAGVGTATCGPGVLPQYLVPLKKQSFEFTLYPVK"
     gene            complement(6535..8859)
                     /locus_tag="Bovatus_RS08300"
                     /old_locus_tag="Bovatus_01700"
                     /db_xref="GeneID:29451447"
     CDS             complement(6535..8859)
                     /locus_tag="Bovatus_RS08300"
                     /old_locus_tag="Bovatus_01700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004326496.1"
                     /GO_function="GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 20 protein"
                     /protein_id="WP_004300811.1"
                     /db_xref="GeneID:29451447"
                     /translation="MKKYILIILILLSPLTAFLQADNLTSPLISIVPRPTQIVPGRGN
                     FTFSAQTVFAVESQEQAVIARNFIDLFTRAAGITPALNVGREEGQVRFVTDSSLKSEA
                     YLLEITPEQILIKASDTKGFFYALQSIRQLLPAAIESEQPVRNVDWRVPAMTVQDEPR
                     FGFRGLLLDPVRCFIPKKNVLRIIDCMAMLKINKLHFHLTDDNGWRIEIKKYPRLTEI
                     GAWRVDRTDVPFHSRRNPERGEPTPIGGFYTQEDIREIVAYAADRQIEVIPEIDVPAH
                     SNSALAAYPQLACPVVKDFVGVLPGLGGRNSEIIYCAGNDSVFTFLQDVFDEILELFP
                     SRYIHVGGDEARKTNWEKCPLCQKRMKKQRLANEEDLQGYFMKRISDYLRKKGREVIG
                     WDELTNSSFLPEESIILGWQGMGTAALKAAEKGHRFIMTPARVLYLIRYQGPQWFEPV
                     TYFGNNTLKDVFDYEPVQKDWKPEYESLLMGVQACMWTEFCNKPEDVDYLLFPRLAAL
                     AEVAWTPAGTKDWSGFLKRMDAYNAHIAEKGIVYARSMYNIQQTVTSVDGHLEVNLEC
                     IRPDVEIHYTLNGSNPAMSSHRYDGPIRVTKTQMVKAATFMNGKQMGETLDLQLTWNK
                     ATAKPLLGNKKNEMLLVNGLRGSLKYTDFEWCNWNQNDSISFTIDLQGREILNKFAIG
                     CITNYGMGAHKPKMIRVEVSDDNRTYHTMGELNFSPEEIYLEGTFRNDYSIDMGGVSA
                     RYVRVTAEGAGICPDEHVRPGQEARVYFDEVIIE"
     gene            complement(8878..10461)
                     /locus_tag="Bovatus_RS08305"
                     /old_locus_tag="Bovatus_01701"
                     /db_xref="GeneID:29451444"
     CDS             complement(8878..10461)
                     /locus_tag="Bovatus_RS08305"
                     /old_locus_tag="Bovatus_01701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009040554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfatase"
                     /protein_id="WP_004300812.1"
                     /db_xref="GeneID:29451444"
                     /translation="MEKLQPNLFFPFAGVAAVASFASCSNKQKPVEQKPLNIVYIMTD
                     DHTAQMMSCYDTRYMETPNLDRIAADGVRFTQSFVANSLSGPSRACMITGKHSCANKF
                     YDNTTCVFDSSQQTFPKLLQKIGYQTALVGKWHLESLPSGFDYWQIVPGQGDYYNPDF
                     ITQNNDTIQKHGYITNLITDDAIDWIENKRNPEKPFCLLIHHKAIHRNWLADTCNLAL
                     YEDKTFPLPDNFFDDYEGRPAAAAQEMSIMKDMDMIYDLKMLRPDKKTRLKSLYEKYI
                     GRMDEAQRAAWDKFYTPIIDDFYKQNLQGKELANWKFQRYMRDYMKTVKSLDDNVGRV
                     LDYLKEKGLLDNTLVVYTSDQGFYMGEHGWFDKRFMYEESMRTPLIMRLPKGFDRRGD
                     ITEMVQNIDYAPTFLELAGAEIPSDIQGVSLVPLLKGEHPKDWRKALYYHFYEYPAEH
                     MVKRHYGVRTERYKLVHFYNDINWWELYDLQADPSEMHNLYGQPEYEPVVKELKEEML
                     KLQEQYNDPVRFSPERDKE"
     gene            complement(10736..12550)
                     /locus_tag="Bovatus_RS08310"
                     /old_locus_tag="Bovatus_01702"
                     /db_xref="GeneID:29451442"
     CDS             complement(10736..12550)
                     /locus_tag="Bovatus_RS08310"
                     /old_locus_tag="Bovatus_01702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008026069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RagB/SusD family nutrient uptake outer membrane
                     protein"
                     /protein_id="WP_004321470.1"
                     /db_xref="GeneID:29451442"
                     /translation="MKKLTYILLLASCLLLASCESWLDEDPQYTLNTQIQFSTSEKAR
                     AALYGCYGYFALTSGGYGQHWQEVPVRYSGFGWAQTNGNTNDMCGWLQCDYTDDLLTN
                     AWYVMYKVINETNAFIANVESTSLEDKDEMAAEARFLRALSYYNLAICWGDVPLKTTP
                     SSHDGVAVPRSPRSEVLDVVRTDLEFAAKYLPETNSDGFPTKWAAEAYLGKLYHTLGC
                     LGDATAWEKAKTYFEGVKGKYDLESKFSNLFVDKIKGSKESIFQLGFQVNGDLSSFNR
                     GSWVFNPAASSYGKSFHRVKCTKAFYDFFAGTYWGDPRIETTFMAKWRKCTNNVGPVA
                     QVEPVPSARDSTYEYPYFTYDSGIKPAGWKNNKLLVGRIPYELLTNKENPSADEILAI
                     TNDETKFDEKYRKGLKDFLNVCTAAGRTGERAAWPHFAKAFDMNMAGIASHKNLILYR
                     YADLLLMLADVYNELDRKDDAINTADIVLARARKSGIKVSAQPAKWESTLTKEQVREK
                     IFFERLFEGAGETEMYQMMRLRGTEYLKKALTVNNNHSITKKWQENNPNATGVWGERI
                     YNNGNLNDETFLKKNLLFPIPRDEMNTNIAITENNFGY"
     gene            complement(12573..15779)
                     /locus_tag="Bovatus_RS08315"
                     /old_locus_tag="Bovatus_01703"
                     /db_xref="GeneID:29451441"
     CDS             complement(12573..15779)
                     /locus_tag="Bovatus_RS08315"
                     /old_locus_tag="Bovatus_01703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004300814.1"
                     /GO_component="GO:0009279 - cell outer membrane [Evidence
                     IEA]; GO:0016020 - membrane [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SusC/RagA family TonB-linked outer membrane
                     protein"
                     /protein_id="WP_004300814.1"
                     /db_xref="GeneID:29451441"
                     /translation="MKNLLKVFLLCFIALFAFAAQSMGQGKTITGQVVDALNESMPGV
                     NVQVKGTTNGTITNIDGKFSISVPNSKSVLIFTFIGYSKQEIVVGNQAKINVQLKEDA
                     QNLDEVVVVGYGTAKKSDLTGATASLRPDANDASKAVSIDGLLQGKIAGLNVTASMST
                     PGAASSVTIRGANSLRGDNQPLYVIDNVPQASTGEFAESAVGSGDFQIAQDPLSAINP
                     NDIEDITVLKDASATAIYGSRGANGVILITTKKGKAGKAKVNVTANFTIANARNLHDM
                     LNLEEYADYTNSKLDQPRYYLQPNGEMRYVFSGNESAYQADPNNPELYKVITYRNWQK
                     EAYTSAFSQIYSASVSGGTAGMKYYISGNFKDINGIVENTGIKQGDLRANLTAELSKK
                     VTLNLILSGSLKQNDMMTGGNTTGGVAGSLARTVLDTAPYIVPDDDPGALESKMNVFS
                     WVNDYDDITNDKTFNGSLNLNWNINKYFSYSLRAGGNIVVNDRKRWYGIQLPPGENVK
                     GLLAISNVNKSNYTVENLLNFNMDLTKDFRLSATAGITYDEYHFLTENVSGNTFSIYD
                     LRTKGLSNAGKVDVKQPIQKDYQLLSYLGRVNLSAYDKYLLTASLRADGSSKFKKGNR
                     WAYFPSFSLAWRMEQEAYMKNIDWLSQLKVRVGYGETGNQGIDPYQSLSIYENKVDYA
                     DGDGNKLTSMQIKSLQNEGLKWERTSSWNAGLDFGFFNGRLNGAFDYYRKNTKDLLVE
                     RALPYSSGFATVMINEGSLLNKGFEFSLNADIIRSNGWKWNVGGNIGFNKTTIENLGL
                     EVSDIGSLKGVRGYLGKTIGDHFGPANIFIEGEAPGLFFGYKTQGIIQEEDVVDGKVG
                     YISSDGSTKYYTSSVGNDMAAGNIKCVDVNEDGVVDANDMAVIGDPNPDFTYGFQTRL
                     EWKNISLSASFTGVYGNDILNTNIRYEQTPSRQAGNLRKDAYYNAWTPENRSNLYPSS
                     TSNVKGVVYDRYIEDGSYLRCSDITLNYILPKAWMTKIGFQNTSIFASVKNAFVITNY
                     SGYDPEVNSFAFDGLRRGVDMNAFPNMRSFVFGLNVTF"
     gene            complement(16078..>16638)
                     /locus_tag="Bovatus_RS08320"
                     /old_locus_tag="Bovatus_01704"
                     /pseudo
                     /db_xref="GeneID:29451439"
     CDS             complement(16078..>16638)
                     /locus_tag="Bovatus_RS08320"
                     /old_locus_tag="Bovatus_01704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009040552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
                     /db_xref="GeneID:29451439"
     gene            complement(16634..17254)
                     /locus_tag="Bovatus_RS08325"
                     /old_locus_tag="Bovatus_01705"
                     /db_xref="GeneID:29451438"
     CDS             complement(16634..17254)
                     /locus_tag="Bovatus_RS08325"
                     /old_locus_tag="Bovatus_01705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004300816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_004300816.1"
                     /db_xref="GeneID:29451438"
                     /translation="MKETLYSRRSNLVVGFHGCDQSIANKIIEGKDDLIASTNDYDWL
                     GHGIYFWENNELRALQYANDMMGRAHSSVKCPAVIGAIIDLGYCMDLTDSLYLGELKE
                     SYNVLVETCRVTGISLPTNSTIGISEDKLLRRLDCAVIETAHQINREVSGREFDSVKG
                     VFWEGVELYPDAGFREKNHIQICVRNPNCIKGFFLPRKLDMNYINP"
     gene            complement(18063..20045)
                     /locus_tag="Bovatus_RS08335"
                     /old_locus_tag="Bovatus_01708"
                     /db_xref="GeneID:29451384"
     CDS             complement(18063..20045)
                     /locus_tag="Bovatus_RS08335"
                     /old_locus_tag="Bovatus_01708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008648817.1"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="WP_004300820.1"
                     /db_xref="GeneID:29451384"
                     /translation="MEQTLVNGIADNLLHNIFNDLSVGLELYDKDGLMIDVNYSRLRS
                     MGIKDKKDILGYNLFNYTSFSDEIKEQIRKGETVRFMAKYDFDDLCRLFPTNLSGIKF
                     FEITVSFVHNDKSEITNYMVITQDITERVLWQNKYDNLYEEVVRSKKELLESEQRMIH
                     LIRQNELVLNNINSGLAYIANDYIVQWENISLCSKSLSYEAYKKGEPCYLTAHNRTTP
                     CENCVMQRARKSGQVESILFNLDNKHVIEVFATPIFNEQGDVDGVVIRVDDVTERQHM
                     IGELEKARSRAEQSDKLKSAFLANMSHEIRTPLNAIVGFSDLLMVTEDQEEKEEFIQI
                     INANNELLLKLINDILDLSKIEAGSVELKYENFDLAVYFNELAASMHRRVVNPQVRLV
                     PVNPYETCTVRLDKNRLAQILTNFVTNAIKYTSKGTIEMGYEKIDENIRLYVRDTGIG
                     IPEDKKDKVFHRFEKLDEFAQGTGLGLSICKAIVEACRGEIGFESEFDKGSLFWAVLP
                     CQFESVNSEPTSSRRNNEKDANKENILDSEETKKVPKRVLVVEDIQSNFFLVSSILKN
                     KCQLLHAPNGLEAVEIVRTQPVDLVLMDMKMPVMDGRTATSEIRKFNAEIPIIALTAH
                     AFDADRVAALKAGCDDYLVKPINGAKLMQTLKEYGC"
ORIGIN      
        1 ttagtccgaa tactgataaa ccttcaaatc gaacttcgga accattgcca gcaaatggtc
       61 gaagatatcc gactgaatac gctcgtattc tttccagacc ttattgcggg agaagaaata
      121 aacctgaata ggtactccgt acatcgtagc ttctttctga ctgataatca aatccaactc
      181 ctgattgacc acaggcagac tacacaaata gcgttcaata tataccctgt acacttgaga
      241 attggtagga acgactcctt cttccggctg ataatccgcc attaatggaa tttctttccg
      301 gtaacggtcc aacatttccg gagtacagaa ttgaagtgta gtcaaatcca aagttatact
      361 cttcatcacc cgtcgtcctc ccgactgtgt cattccccgc caattctgaa aaggactgct
      421 cactaatgta taaggaggaa tagtggaaat ggtattatca aaattctgga tcttgactgt
      481 attcagcgtt atttcctgta caatgccatt tgcgtcaccg gaaggaagcg tcacccagtc
      541 ccccggacga accatatcgt tggcagaaag ctggataccc gccacaaaac ctaatatgga
      601 atctttgaat actaacatta aaatagccgc tgaagcgccc aagcccgcaa acaaagtagc
      661 cggagactta ttcacgataa tagcaatgat tacaatcccg ccaacaaaga aaagaagcac
      721 ctgcaacact tggataaaac ctttcatcgg gcggtctttc atcgactctc ttccgtcata
      781 gatatccatt atcatcaaca gaatcccatt tatagccaat agtaaagaga aaataatata
      841 aatgacgcac gccttctggg aaatcagcaa cagctctttt ccacggataa aagccatcgg
      901 caacaacgaa taaaccagaa aagccgggat ggtatgaatc aaattatgaa ataccctacg
      961 cttcatcaac aatgtattcc attgatgagg tttacgtctc gtatactgtt tcatacctcc
     1021 aataagaatt gcctggcaaa gataattcaa aacgatagca accactatca tcagtaaagc
     1081 cataatagtc tcatcaaaac gatcggcaac tgccggatct attccccaat taatgagggt
     1141 tttattcatc cattttccta aatctactac taacataact tctgtctttt ttttataaat
     1201 aacagtaaaa tattcatttg gtttagaaaa aaagagacta gtatccgatt tatcaagaat
     1261 caagacaccg gtctccactg ctactctcta agcatatcat ttttcgatga gggctccatc
     1321 agggaatcac catcacccct atttcattca tatttacttt agcaacggta gcatcaggtg
     1381 tagtggcctc cagtttaatg aaacgtgcct gtactttctg actgaaagca accgtctgtg
     1441 gcaacggatt atgcataata ttgctgaact ctccactggc aggcacttct ttccagctct
     1501 taccatccat gcttacaaag aattgataac ggaatgccat cgtcggcttt acctccgctt
     1561 ttgaaggcgc gtacgtgaaa ctgctcaatg ttaccgtctt ccccaaatca atcgttaatg
     1621 gagaagcagc aacctgtttc catccggaac gcggcaaatt attccagtct tctttcgttg
     1681 tttcttcctg caaaggttct gcataataag cggcaacctg actaacgtaa gcagtcaacc
     1741 ggcactcgtc tattctcacc cggagcttat tggcattaac tgccggaaag cgcaacatac
     1801 gtttatatcc tatcgtcgta ccttttccta cttctttcca gccattatcc gtcaaggctt
     1861 ccacagtaaa agcctctacc ctctgccctt tcgttatatc ttcctgcaac atgaccagat
     1921 tgatttccga tttggacttc aaggcataga cagcctcacc gcccgaagta gtgctccagt
     1981 attttcttcc gtttttcacc cggttgtcag caaacgtttg ttgccgataa tcagcaaact
     2041 ctttcaaccg cttgatatca gcttcatgaa tcagtcccct ccggtcaggt ggaatattca
     2101 gtagaagcac tgaattatat cctaccgact ggaaataaat atctgataaa tgcttcaaag
     2161 atttcacttt accatcttcc tccgcatgat agaaccatcc cggacggata gatacgtcga
     2221 cttccgaagg ataccagaat aattccgtag ctttctccaa tatcttacga cttcccaaat
     2281 cctctgcttt actgaaaaca cccaaacgtt tgttgttctc ttgtgaacgg gcatatatac
     2341 cgggagtcaa cacagttgcg ttccattccg tttcacggcc tactcctttc tcgtttccga
     2401 cccagcggac atcatccccc ataattgcca tcacagcttt gggttggagg cgttggatgg
     2461 tttggtaaaa agcgtcccag tcatacactt gcttctttcc gttcggacct tctccattcg
     2521 ccccgtcgaa ccagacttca tgtacttcac cataattggt gagcaattcc gtcaattgcc
     2581 gaataaaaaa atcattgtaa cggggagagt ctccataaca ttccgcattc cggtcccagg
     2641 gagaaagata tactccaaac ttcatatcat atttgtcaca ggcagcacga agttctttca
     2701 ctacatcgcc ttgtccgttt ttccaaggag aagaggccac ggaatgtttg gtagtagccg
     2761 ttggccaaag gcagaaaccg tcgtgatgtt ttgcagtcag aagcaccatt ttaaagccgg
     2821 cttccttgag ggtacgtacc cattgttcag catccagttc cgaaggatta aagagcgcgg
     2881 gatcttcttt cccgtccccc cattcacgtc cggtaaaggt gttgatacca aaatgaagga
     2941 aagctgttaa ttccatttgt tgccaagcgt attgctgtgg agtaggtacc agacgcgctg
     3001 ccatatcaac cttctgttcg atagttgcac tttgaggaaa ttcaacatgc ttcacatagt
     3061 aattttcttt tttctgcgcc tgcgctccac tcatgagagt aacagacaat aaaagagagg
     3121 ttagtagttt attcatggtc tattaattat tgcaatcgta caaagataaa ataaaggtgc
     3181 agatttcacg atcctcatgg aatattttct tacgacattc catccattca gtgtaacccc
     3241 cacctttata tataatctaa ataacctatt gatttagtat ctatttcacc ggataaaggg
     3301 taaattcaaa actctgtttc tttaatggaa ccaagtattg cggtaatact ccgggaccac
     3361 aagtagccgt tcccacacct gcctgttcag catccagatg cactgtcagc aatccatcgc
     3421 gttccagttc attgatatgg cgggccttct ctaataatac atccgagaaa ggaatgatac
     3481 taaactggaa agcacgatcc gactcaacaa agataccttc gccggaagta tctgccaact
     3541 tcacccaacg tacatcggtg cggttgcttg tagattgcgg agcaacataa tagtggaaca
     3601 tccgttccgg tgtggtctga tatacaccga ttttaccgga ctgattgcgg tcaatatagg
     3661 tttcattatc tccacgtccc aagtaagaaa cctgatcgta ggcgttcgac acacggaacg
     3721 tcaatcccaa gcgtgccatt gatttcacga tggtcgtgtc gggttggaaa gttgtatgta
     3781 ctttcagtgc accgtttcta tccagtgaat aaacaaagtc agcaattcct accctttgcg
     3841 tttttgcatt tagaatttct acacgggcag tggtcgaagt cttactttcc ttcaatgaca
     3901 ctactttctg ggtcagacaa tccaatcccg catcacgcca caagcgtgcg ccgttcttat
     3961 cccggttgtc attatccgtt gccgggcggt aaaggctcaa tgtcagcgga gtagccaata
     4021 attctttgcc gttcaagttc aatgaagtca gcgcgcctgt ttgcttatca acggtgaaag
     4081 tcgtttcacc tgctttttgc ggacggtagc ctgtgtagtt cttattaccg gcaaatacaa
     4141 actggtcgta tgccacctcc caatccttat ctatcattga agaagcttca cgacgggtcc
     4201 agctgatatt caaataagcc tcacggactg tattcggaag ttttacagcc cccaaagtaa
     4261 catcaacagt agcgtgtggt gcacaatcaa ccgtttttgt accttccgcc aaaatcttgc
     4321 cattatctgc cgtcacattc cagttcagta catactcatt caagttagag aaatcatacc
     4381 agttcttgac acggatagtc agattcttct gattcgccag cgttactttt atgttctgat
     4441 atactttctt tacttcgagc aaatgcgggt gcggttcacg gttggcgccc accaaaccgt
     4501 tacagcagaa gtttccgaaa cttggaattc cttccggtcc gtaatcaccg ccatacgtcc
     4561 agtaccattt accattcttg tctatttcgc ggaatgactg atccacccag tcccaaacgc
     4621 agccaccttg tgccatcgga ttgttttcaa atacgtccca gtattctttc agtccgccgc
     4681 aactgttgcc catcgcatga agatattcac aaagaatgaa agggcggtag atgtctttct
     4741 cttttacgta tgctttgata tcgtctacac tgcggtacat acgacagtaa atatccgtat
     4801 tatagttcaa ttcggcacgt tcatactgta cagggcgagt tttctctacc gatttcagcc
     4861 agtcataagt acgttcgaag ttaattccgt ttcctgcttc atttcccaat gaccagataa
     4921 cgatagccgg gtgattctta gaacgttcat acatccggtg agtgcgatcc atgtgtgcag
     4981 tcagccaggt actatccttg gctagggaag caggaccata tcccattccg tgagattcga
     5041 tgtttgcctc atcaatcatg tacaaaccgt aacggtcgca aagttgatac cagtaaggat
     5101 gtgtaggata atgcgagtta cgcaccatgt tgatattgtg ctgcttcatc agtttgatgt
     5161 ccagttccat cagctccttg ctcacggtac gtcccagttg agaatgctcg tgtcggttgg
     5221 ttcccttcac caataccgga acgccgttga tgcagaaacg tccgtctttg atttccgagg
     5281 tacggaagcc gacttcacaa ccagtcagtt cggttacctt gccttgttca tccttcagtt
     5341 cgagtattaa tgtgtaaaga tgaggatgct ctgcactcca agcctttaca tcgggaatat
     5401 tcttttcatc aaacgtgata aaattgctca atccgcggga ttttatccgg atagcatcct
     5461 gcaggacagt tttgccatcg gcgtctttca gggtataagc aatagaagta gctccagata
     5521 tagcagaatg tccctctacg gtcacttcaa gtccgaaaat accatctttg tatttctctt
     5581 tttctaaaga agcattcagt ttataatccg caatgtactg tttgggagta ctgtaaagat
     5641 acacgtcacg ttcgatacca ctcaaacgcc acatatcctg acattccaga taagcacccg
     5701 aactccagcg atacacttcc aaagcaacca cattttcgcc ttcattgagg acatctgtaa
     5761 tatcccattc ggcagccgtc tttgatccct gattatagcc aagtaatttt ccattcaccc
     5821 atacataata gaaagaaatg actccttcac aacacagtac taccctgcgt cctttccagt
     5881 cggcaggcac tttgaaggta cgtcggtagg agccgacttc attctctgca taaggcacca
     5941 gcggcggatt cttcttgaag ttgaacattt tatcatcaaa ctcatacgtt tcgttgacat
     6001 agatagccgt gccatacccc tggcgttccc agttaccggg cacattgata tccgcccatc
     6061 ctcctgtata ataagaaggt tggtaaaagt ccttcggacg attatcggga ttcttcaccc
     6121 aatggaattt ccactttcca ttgagactca tataaaaagg agactgttca taccctcccg
     6181 gcttttcaat gtcggaagcg ttggcgtaag gccatacgta tgtgtgagga gcgagtttgt
     6241 tcagtcccac cgcatactgg ctttgccatt cgggcaacgg ttgttgttgc gctaaagtga
     6301 aagtagcagt cagtcctgac aatagaacta aaagagttcg tttctttaag ctaatattca
     6361 taagcatgtc atcataattg gtttatataa taaattaggc acagattaag ctgattgacg
     6421 ctattatttt atatactcat cattctaaaa accgtgaaat tcgtgtaatc cgtctctaat
     6481 aatataagat tattctgcaa gaacacttaa ttgctgtttt taactatttg attactattc
     6541 tataatcact tcatcaaaat agactctcgc ttcctgaccg ggacggacat gctcgtcggg
     6601 acatatcccc gcaccttccg ccgtcactcg gacataacgg gcagatactc cgcccatatc
     6661 tatcgaatag tcatttctaa aagttccttc cagatagatt tcttccggag agaagttcaa
     6721 ttctcccata gtatggtagg ttcgattgtc atcggaaact tctacgcgaa tcatcttcgg
     6781 tttatgtgct cccattccat aattcgtaat gcaaccgatg gcaaatttat tcaaaatctc
     6841 ccgcccctgc aaatctatcg tgaaagatat agaatcattt tgattccagt tacaccattc
     6901 aaaatcagta tatttcaggc ttccccgcaa tccgttgact aacaacattt cgttcttctt
     6961 attgccaagc aaaggttttg ccgtagcttt gttccatgtg agttgcaagt ctaaagtttc
     7021 tcccatttgc ttgccgttca taaaggtagc ggctttcacc atttgtgtct tcgtcacacg
     7081 gataggtccg tcgtaacgat gagaagacat tgccggatta cttccgttca gtgtataatg
     7141 aatctctaca tccgggcgga tacattccaa attcacttcc aaatgtccgt ccactgatgt
     7201 caccgtctgt tgtatgttat acattgaacg ggcatagaca attccttttt ccgcaatatg
     7261 cgcgttgtat gcgtccatcc gcttcaagaa tccagaccag tccttcgttc ctgcgggcgt
     7321 ccatgccact tctgctaaag cggccaggcg gggaaacaaa agataatcca catcttcggg
     7381 tttattacag aactctgtcc acatacaagc ctgtactccc attaacaaag actcatattc
     7441 cggtttccaa tccttctgta caggttcgta atcgaaaaca tctttcaggg tattgttgcc
     7501 aaaataggtt accggttcaa accattgcgg tccctgataa cgaatcaagt ataagacacg
     7561 cgccggagtc atgataaaac gatgtccctt ttcggcagct ttcagagcag ccgtacccat
     7621 tccctgccag cctaggataa tagattcttc aggaagaaaa gagctgtttg tcaactcatc
     7681 ccagccaatc acttcacgac ctttcttacg cagataatca ctgatacgtt tcatgaagta
     7741 accctgcaaa tcttcttcat tggccaaacg ctgttttttc atccgttttt ggcaaagcgg
     7801 gcatttctcc cagtttgtct ttcgcgcctc atctccacca acatgaatat agcgagaagg
     7861 gaaaagctct agaatttcgt caaaaacatc ttgcaagaat gtaaatacgc tatcatttcc
     7921 cgcacagtag ataatctcgg aatttcgtcc tcccagtccg ggaagtacac cgacaaagtc
     7981 tttcacaacc ggacaggcaa gctggggata agcagccaga gcagagttac tgtgtgccgg
     8041 tacatctatt tcgggaatga cttctatctg tctgtcggct gcataagcta caatttcccg
     8101 gatgtcctcc tgcgtgtaga aaccgcctat cggagtaggt tctccccgtt ccgggttacg
     8161 acgtgagtgg aaaggcacat ctgtacggtc tactctccac gctcctattt ccgtcaaacg
     8221 ggggtatttc tttatttcaa tccgccagcc gttatcgtct gtcagatgaa aatgaagttt
     8281 gtttattttc agcatcgcca tacagtcaat gattcgcagt acattctttt tagggataaa
     8341 acaacgtacc ggatccaaca gtaatccgcg gaaaccgaaa cggggttcat cctgaaccgt
     8401 cattgccgga actctccaat cgacattccg gaccggttgt tccgattcta tggcagccgg
     8461 cagaagttgg cggatagatt gcagggcata gaaaaagcct tttgtatccg aagctttaat
     8521 gagtatctgt tccggcgtaa tctccagtaa gtaggcttca ctttttaaag aagaatccgt
     8581 cacaaaacgg acttgtccct cttcacgccc gacattcaaa gcaggagtta ttccggcagc
     8641 acgagtaaac aagtcaataa aattgcgagc aatcacggct tgttcctgac tttctaccgc
     8701 aaacaccgtt tgggctgaaa aggtgaagtt gccacggccc ggcacaatct gtgtcgggcg
     8761 tggtactatt gaaattaaag gggatgttaa gttatcagcc tgcaaaaacg ctgtcagtgg
     8821 cgaaagcagt atgagaatga ttaagatgta ttttttcatg gcgtatgtac attggtatta
     8881 ttccttgtct ctctccggtg agaagcggac aggatcattg tattgctcct gaagtttcag
     8941 catttcttct tttagttctt tcactaccgg ttcatattca ggttgtccgt agaggttgtg
     9001 catttccgac gggtctgcct gcaggtcgta gagttcccac cagttaatgt cattatagaa
     9061 atgaaccagt ttatagcgtt ccgtacgtac accataatga cgtttcacca tgtgttcagc
     9121 gggatattcg tagaaatgat agtagagagc cttccgccaa tctttcggat gttcgccttt
     9181 cagcaagggg acgagggata caccttgtat gtctgaagga atctctgctc ctgccaattc
     9241 gaggaaggta ggtgcataat cgatgttctg aaccatttcg gtgatgtcgc ccctacggtc
     9301 gaatcctttc ggcagacgca tgatgagtgg tgtacgcatg gattcttcgt acatgaaacg
     9361 tttgtcgaac caaccgtgtt cgcccatgta gaatccttgg tcggaagtat agacaacaag
     9421 tgtgttatcc agtaatcctt tctctttcag gtagtcgagt acacgaccaa cattgtcgtc
     9481 cagcgacttc accgtcttca tataatcgcg catataacgc tgaaatttcc agttggctag
     9541 ttccttgcct tgcaggttct gtttatagaa gtcgtctatt attggggtgt agaatttgtc
     9601 ccatgcagca cgttgtgctt catccatacg accaatatat ttctcatata aggatttcag
     9661 acgggtcttt ttgtcgggac gaagcatttt gaggtcataa atcatgtcca tgtctttcat
     9721 aatactcatc tcttgtgcgg cagcggcagg gcgtccttcg taatcgtcaa agaaattgtc
     9781 cggtagcggg aaggttttat cttcgtacaa agccaggttg caagtatctg ccaaccaatt
     9841 acggtgaata gccttatggt gaatcaaaag acagaaaggt ttctccggat tgcgtttgtt
     9901 ttctatccag tcaatggcgt cgtcagtgat aaggttcgtg atatatccat gtttttggat
     9961 agtgtcattg ttctgtgtga tgaaatccgg attgtagtag tcgccttgtc cggggacaat
    10021 ctgccagtaa tcaaaaccgg aaggcaaact ttcaagatgc catttaccta ccagtgctgt
    10081 ctgataaccg attttctgca acagcttcgg aaaagtctgt tgcgaactgt cgaatacgca
    10141 agtggtatta tcatagaatt tattagcaca actatgttta cctgttatca tgcaggcacg
    10201 actaggaccg cttaatgaat tggctacaaa actttgagta aagcgtacac catcggcagc
    10261 aatacggtcg agattgggtg tttccatgta gcgtgtgtca taacagctca tcatttgagc
    10321 tgtgtggtcg tctgtcataa tgtagacgat attcaaaggt ttctgttcca caggcttttg
    10381 cttgtttgaa caggaagcaa aggaagctac agctgctact cctgcaaaag gaaagaataa
    10441 gtttggttgc aatttttcca taaaacaact ttatattaga ttgtagtgac aaaggtagag
    10501 ccccgtcaac aaaatccatg ttcacaaata accaattaat ttccaatatt ctccatttct
    10561 acctgtttca gaaagaaaaa tggtaaaaac acgatttaca gctcattccc aatcctgcaa
    10621 atccaagaaa atatatacaa cgatttctat ttataaaaga aaacccgaat gaagagcaga
    10681 aacactcctc ctctgcattc gggaaatcta aaacaaccta ttataactac tatttttaat
    10741 agccgaagtt attttccgta atagctatat tagtattcat ttcatcacgc ggaatgggga
    10801 acaacagatt ctttttcaaa aaagtctcat cattcaaatt tccattatta taaatgcgtt
    10861 ctccccaaac tcccgttgca ttaggattat tttcctgcca ctttttagtt attgagtgat
    10921 tattattcac agtaagtgct tttttcaaat attcagttcc acgtaaacgc atcatttgat
    10981 acatttcagt ttcaccggca ccttcaaaaa gtctttcaaa gaatatcttt tcacgtactt
    11041 gctcctttgt taatgttgat tcccatttgg ctggttgtgc cgaaacctta attcctgact
    11101 tacgtgcacg tgccaacacg atatctgctg tattaattgc atcgtctttt ctatccaatt
    11161 cattatagac atcagccaac atcaataata aatctgcata acgatataaa attagattct
    11221 tatgactggc aataccggcc atattcatat caaaagcttt tgcaaaatga ggccatgctg
    11281 ctctttctcc tgtcctaccc gccgcagtac atacattcaa aaaatccttc aatcctttgc
    11341 gatatttctc atcaaatttg gtttcatcat ttgtgatagc caaaatttca tccgcactcg
    11401 gattctcttt attagtcaat aactcataag gaattctacc aactaacaac ttgttatttt
    11461 tccaacctgc aggttttata ccgctatcat aagtgaaata aggatattca taagtagagt
    11521 cacgggcaga cggtacaggc tctacttgag ctacaggtcc gacattgttt gtacattttc
    11581 tccattttgc cataaatgta gtctcaatac gaggatctcc ccaataggtt cccgcaaaga
    11641 aatcataaaa tgctttcgta cacttcactc tatgaaagct cttaccatac gatgatgcag
    11701 caggattaaa cacccaagat cctctgttaa aagaagacaa gtcaccattc acttgaaatc
    11761 ccagttgaaa tatagactct ttagaacctt taatcttatc aacaaataaa ttagaaaatt
    11821 tcgattccag atcatattta cctttcactc cttcaaaata ggtctttgcc ttttcccaag
    11881 ccgtagcatc acccaaacag cctaaagtgt gatataactt acctaaatat gcttctgcag
    11941 cccatttggt tggaaatccg tcagaatttg tttccggcaa atatttcgca gcaaattcca
    12001 agtcagtccg taccacatcc agcacctctg aacgcgggga acgaggtaca gctacgccgt
    12061 catgagaaga aggggttgtc ttcaagggta catctcccca acatattgca aggttataat
    12121 aagataaagc acgcaagaaa cgagcctctg cagccatttc gtctttatcc tctaaagaag
    12181 tgctttccac attggctata aatgcattcg tttcattaat cactttatac attacatacc
    12241 atgcatttgt caacaaatca tctgtatagt cacattgcag ccatccacac atatcatttg
    12301 tatttccatt agtttgagcc catccgaaac cactatatcg tacaggaact tcttgccaat
    12361 gctgaccata tcctccacta gtcaatgcaa aataaccata gcatccatat aatgctgcac
    12421 gcgccttttc agaagtagaa aactgaattt gtgtattcaa agtatattgc ggatcttcat
    12481 ctaaccacga ttcacaagaa gccaacaata agcagcttgc caataataat atataggtta
    12541 attttttcat tttcataatc atttattgta aattaaaaag ttacattcaa gccaaacaca
    12601 aaagaacgca tatttggaaa agcattcata tcaacacccc gacgcagacc atcaaatgca
    12661 aagctattta cttccggatc atatccacta taattggtaa taacaaatgc attcttcact
    12721 gaagcaaaaa tgctggtatt ctggaacccg atcttagtca tccacgcttt aggcaaaata
    12781 taattcaacg taatatctga gcaacgcaaa taacttccat cttctatata acgatcataa
    12841 acaactcctt ttacatttga agtagacgac ggatataaat tagaacgatt ctccggagtc
    12901 catgcattat aataagcatc ttttctcaag tttccagcct gcctggaagg agtctgttca
    12961 taacgaatat ttgtatttag aatatcatta ccataaacac ctgtaaagga agcagaaaga
    13021 gagatattct tccattccag acgtgtttgg aaaccgtagg tgaaatcagg attcggatca
    13081 ccaattacag ccatatcatt agcatctacg acaccatctt cattcacatc cacacattta
    13141 atattaccag ctgccatatc atttccaaca gatgaagtgt aatattttgt agaaccatcc
    13201 gacgagatat atcctacttt gccatcaact acatcttctt cctgaataat tccctgtgtc
    13261 ttataaccga aaaatagtcc aggagcttca ccttcaataa aaatatttgc aggtccaaaa
    13321 tgatcgccaa tcgtcttacc taaatagcca cgtactcctt tcaaagagcc tatatcggaa
    13381 acttccaaac ccaaattttc aatcgtagtc ttattgaaac cgatatttcc gcctacattc
    13441 catttccacc cgttactacg aatgatatca gcatttaaac taaactcaaa acctttattc
    13501 aataacgatc cttcattgat catcactgtt gcaaatccac tggaatatgg caaagcacgt
    13561 tcaaccaaca aatcttttgt gtttttacgg taatagtcaa atgcaccatt cagacggcca
    13621 ttaaagaaac caaagtcaag accagcattc cacgaagaag tacgttccca cttcaagccc
    13681 tcattttgca aacttttgat ttgcatagac gtcagtttat tcccatctcc gtcagcatag
    13741 tccaccttat tctcataaat agataacgac tgatatggat caataccttg attgcctgtc
    13801 tcaccatagc ccacacgtac cttcaactga cttaaccagt cgatgttctt catataagct
    13861 tcctgttcca tacgccatgc taatgaaaaa gacgggaaat atgcccaacg attacctttt
    13921 ttaaatttac tggatccgtc agcacgcaat gaagcagtta acaagtactt atcataagct
    13981 gataaattaa cacgccctaa atatgaaagc agttgataat ctttttgtat aggctgtttc
    14041 acatccactt ttcctgcatt agacaatcct tttgtacgta agtcatagat agaaaaagta
    14101 ttacctgaaa cattctctgt cagaaaatga tattcatcat aagtgatacc cgctgttgcc
    14161 gacagacgaa agtccttagt caaatccata ttaaagttta acaggttttc caccgtataa
    14221 ttagacttat tgacattact gattgccaac agacctttta cattttctcc tggaggcaac
    14281 tgaatcccgt accaacgttt acggtcattt actacaatat ttcctcctgc acgcagacta
    14341 tacgagaaat atttattgat gttccaattc agattcaaac ttccgttaaa tgttttatca
    14401 ttcgtaatat catcgtaatc attcacccaa ctaaagacat tcatttttga ttccaaagca
    14461 cccggatcat catcaggaac aatataagga gctgtatcaa gaaccgtacg agccaaagat
    14521 ccggcaacgc ctccggttgt attgccacct gtcatcatgt cattctgctt caatgaaccg
    14581 ctcaatatca aatttaaagt tactttctta gataattcag cagttaaatt agcacgtaag
    14641 tcaccttgtt ttattcctgt attttctaca ataccattaa tatctttaaa attaccggag
    14701 atataatatt tcataccggc agttcctcca ctgacagaag ccgagtaaat ttgtgagaaa
    14761 gctgatgtat atgcctcttt ttgccagtta cgataggtaa tgaccttata taattccgga
    14821 ttattcggat ctgcctgata agcggattca ttaccactaa atacgtaacg catttcacca
    14881 ttaggttgca aataatatcg cggttggtcc aatttagaat tagtgtaatc ggcatactct
    14941 tccaaattta acatatcgtg caagttacgt gcattagcta tcgtaaagtt tgctgtaaca
    15001 tttacttttg cctttccggc ctttcctttt tttgttgtaa taagaattac accattagca
    15061 ccacgagaac cataaatcgc agtagcagaa gcgtctttca agacggtaat atcttcaata
    15121 tcattaggat ttattgcact caacggatct tgagctatct ggaagtcacc acttcctaca
    15181 gctgactcgg caaattcacc agtagatgct tgcggtacat tatcaatcac atataatggc
    15241 tgattatctc cacgtaatga attagcacca cgaatagtaa cagaagaagc agcccccgga
    15301 gtagacattg aggctgttac atttaaacct gcaatcttac cttgtaatag tccatcaata
    15361 gacacagctt ttgaagcatc attcgcatca ggacgaagac tggcagtagc acctgttaaa
    15421 tcgctctttt tagctgttcc ataaccgaca acgactactt catccaaatt ttgtgcatcc
    15481 tcttttaatt gaacattaat tttagcctga tttccaacca ctatttcttg tttggaataa
    15541 ccgataaaag taaagatcaa cactgatttt gagtttggaa cggaaatgga gaattttcca
    15601 tcaatgttgg taattgtccc attagtagta ccttttactt gtacattgac accaggcata
    15661 ctttcattta gagcatccac tacctgtccg gtaatggtct ttccttgtcc catagattgc
    15721 gcagcaaacg caaacaaggc gatgaaacat agcagaaaaa cttttaatag gttcttcata
    15781 gaagtcattt ttataaatta ttaaatttta aagattaaaa agctcattcc agactttatt
    15841 tgctgaaatc catacgcaaa tatagatgtg gttactaaat atgtatgttc tatttttact
    15901 ataattcttc catttttatc taaaatcatc catttcatcg acaaattgcg gtattataga
    15961 cattgttgga catcttacga atcaaaaaaa gaaagcggaa gtattcattc ctgaatattc
    16021 ccgcctcttt tatattttat cctaatataa ctacaacaat tttcctacga agatatatta
    16081 taggttttct atatcagaag attgaagacc cgtgtatttg ataattgtat caatggatat
    16141 tccgtcctcc ctcatctttc gagcaatttc aatttgcttc ttttgctctc ctttctccat
    16201 ccctttctcc attccttcct ttattccttc tcttatccct tcctttagcc cttctttcat
    16261 cccttcttca gccgcttttc tccgcatctc ttcgttttta cgccgttcat cctcctctac
    16321 gatttgattg actctatatc gatctaatgc cttatcataa gcgatacgat tttcttccga
    16381 aagatcggca actgctacca atctcgccag atgttcaaac acttgttctt tcaaagcatc
    16441 cggcattcta ttccaattgc tcatattctt cagtgcataa atcaatttat catataatgt
    16501 atggcagtcc gacaagtcct ttgtaaaata aggaaattgc aaataaatct gccggagatg
    16561 cagatttaca atcttcccag tatcacggcc ggaaagaacc gtatccgtac ggaatttagc
    16621 ctccaaattt tccttacggg tttatatagt tcatatctaa tttacgaggc aaaaagaacc
    16681 cctttataca attaggatta cgcacacata tctgaatatg attcttttct ctaaaccctg
    16741 cgtctggata gagttcaaca ccttcccaaa atacaccttt cactgaatca aattctcttc
    16801 ctgatacttc tctgttaatc tgatgtgccg tttcaataac tgcacaatcc aatctgcgca
    16861 atagcttatc ttcagatatt cctattgtag aatttgtagg aagagaaatc cctgttacac
    16921 gacatgtttc cacaagtaca ttataagatt ccttcaattc acctaaatac aatgaatctg
    16981 tcaagtccat gcagtatccc aaatcaataa tagcaccaat tacagctggg catttaacag
    17041 atgaatgagc tctacccatc atatcatttg catattgcaa tgcacgaagc tcgttgtttt
    17101 cccaaaaata gattccatgt cccagccaat cataatcatt agtacttgca attagatcat
    17161 ctttaccttc aattatctta tttgcaattg attgatcaca accatgaaag ccaacaacaa
    17221 gattagaacg acgtgagtat aatgtttctt tcatctataa attttggtaa gttcacctga
    17281 tttagagact attccagctt tttttagaaa agattgggca ttccttttat tagctgtaat
    17341 tttcttcact acctcaactc taagttcttc ccgagttttt attttctttg tagcagtcat
    17401 tatatacctc ctttcttgta caaagataac tatttaaatc cataaacata aaaaacaatc
    17461 ccaaacttta cggatttata gccttttaag taagccgtct ccctttcaat tcctccaaac
    17521 aaacaagaga aatgttcttt ttttcagatt aagaaagaaa acaaaactgt tgaagatggg
    17581 aatccggaat taaaagcatc catattatca catatatatg catattactg ccacaataca
    17641 gcatatattt tcagataata tgcgttttct ttaaagaaat aaatgatttt cctcggtgag
    17701 caataagcca ttcctcggtg aggaacacat ccttcctcac cgagaaagcc ttccatactc
    17761 accgaccaag ttataaaagc ccttggaaaa gcccgtttat aggctagttc atcatcatat
    17821 acgcaccaaa aaagaatgat aaaacaaact acatacgggc aaacagtaag catatagata
    17881 gcaatacaga ggaattattt atttttagac aggaattatc caggataaca aacaatccta
    17941 cattctttca tccaaaatgc agagcgtttt ttccttcacc acaaacaagt gactgatata
    18001 ttaaaaacag aaagaataga atataccctt tttcagatca gcacatttct aatcccatcc
    18061 tttcaacaac catactcttt cagagtctgc atcaacttcg cgccattgat cggcttcacc
    18121 agataatcat cacaaccggc tttcaacgca gctacccggt cagcatcaaa ggcatgagca
    18181 gtcagggcga taattggaat ttcagcattg aacttccgga tctccgaggt tgcagtacgt
    18241 ccgtccataa caggcatctt catatccatc agtaccaaat ccaccggttg ggtacggaca
    18301 atctcaactg cctccagtcc attcggtgcg tgtaacaact ggcatttgtt tttcaagata
    18361 gaagatacca aaaagaagtt actttgtata tcttcaacga ccagtactct tttaggtact
    18421 ttttttgttt cttcggagtc aagaatattt tctttattcg catccttctc attgttccga
    18481 cgtgaagaag tcggttcgct gttaaccgat tcgaactggc atggcaaaac cgcccaaaat
    18541 aaagaccctt tatcaaattc tgactcaaag cctatctctc ctctgcaagc ctcaacaatg
    18601 gctttacaaa tggacaatcc caatccggtt ccctgtgcaa attcatccag tttctcaaaa
    18661 cgatgaaata ctttatcttt tttatcctcc ggtatgccga tacctgtatc gcgaacgtaa
    18721 agacgaatat tttcgtctat cttctcatac cccatttcaa tagttccttt ggaggtatat
    18781 ttgatagcat tagttacaaa gttagtgaga atctgcgcta accggttttt atccaaacga
    18841 acggtacaag tttcataagg attcacggga actaaccgaa cctgcggatt tactacacga
    18901 cgatgcatcg aagcagctaa ttcgttgaaa taaacagcca aatcaaaatt ttcgtatttc
    18961 agttctaccg agccggcttc tattttcgaa agatccagta tgtcgttaat cagcttcaaa
    19021 agcaactcat tgttggcatt gataatctga ataaattctt ctttttcttc ttgatcttcc
    19081 gtcaccatca ataagtcgga aaaaccaacg atagcattta acggtgtacg aatttcatgg
    19141 ctcatatttg ccagaaaggc ggatttcaac ttatcggatt gttcagcgcg gctccttgcc
    19201 ttttcaagtt caccaatcat gtgctgccgc tcggtaacat catctacacg aatcacgaca
    19261 ccgtcaacat ctccctgttc attaaatatg ggagtagcaa agacttctat gacatgcttg
    19321 ttatccagat taaacaagat agactctacc tgaccggatt tccgggcacg ttgcatcaca
    19381 caattctcac aaggagtggt gcgattatgg gctgtcagat agcaaggttc tccttttttg
    19441 taagcctcat aagaaaggct tttactacaa agcgagatat tctcccattg tacgatatag
    19501 tcgttcgcaa tatatgccaa tcccgaatta atattgttca ataccaattc attctgacga
    19561 atcaaatgga tcattctttg ttcgctctca agaagttctt ttttcgaacg cacaacctct
    19621 tcgtaaagat tgtcatattt gttttgccac aaaacacgtt cggtgatatc ttgagttatc
    19681 accatataat tggtaatttc agacttatca ttatgtacaa aagaaacggt aatctcgaag
    19741 aattttatac cggacagatt agtaggaaaa agacggcaca agtcatcaaa atcatatttt
    19801 gccatgaaac gcactgtttc tccttttctg atctgttcct tgatttcatc agagaaactg
    19861 gtgtagttga atagattata gcccaaaata tcctttttgt cttttatccc cattgatctc
    19921 aaccgtgaat aattgacatc tatcatgaga ccgtccttat catacaattc caagcctaca
    19981 gacaagtcat taaagatatt atgcaataag ttatcagcta tcccatttac caaagtctgt
    20041 tccat
//
