LOCUS       NC_002973               4383 bp    DNA     linear   CON 30-JAN-2025
DEFINITION  Listeria monocytogenes serotype 4b str. F2365, complete sequence.
ACCESSION   NC_002973 REGION: 2802883..2807265
VERSION     NC_002973.6
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN02603980
            Assembly: GCF_000008285.1
KEYWORDS    RefSeq.
SOURCE      Listeria monocytogenes serotype 4b str. F2365
  ORGANISM  Listeria monocytogenes serotype 4b str. F2365
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Listeriaceae;
            Listeria.
REFERENCE   1  (bases 1 to 4383)
  AUTHORS   Nelson,K.E., Fouts,D.E., Mongodin,E.F., Ravel,J., DeBoy,R.T.,
            Kolonay,J.F., Rasko,D.A., Angiuoli,S.V., Gill,S.R., Paulsen,I.T.,
            Peterson,J., White,O., Nelson,W.C., Nierman,W., Beanan,M.J.,
            Brinkac,L.M., Daugherty,S.C., Dodson,R.J., Durkin,A.S., Madupu,R.,
            Haft,D.H., Selengut,J., Van Aken,S., Khouri,H., Fedorova,N.,
            Forberger,H., Tran,B., Kathariou,S., Wonderling,L.D., Uhlich,G.A.,
            Bayles,D.O., Luchansky,J.B. and Fraser,C.M.
  TITLE     Whole genome comparisons of serotype 4b and 1/2a strains of the
            food-borne pathogen Listeria monocytogenes reveal new insights into
            the core genome components of this species
  JOURNAL   Nucleic Acids Res 32 (8), 2386-2395 (2004)
   PUBMED   15115801
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4383)
  AUTHORS   Nelson,K.E., Fouts,D.E., Mongodin,E.F., Ravel,J., DeBoy,R.T.,
            Rasko,D.A., Kolonay,J.F., Angiuoli,S., Gill,S.R., Paulsen,I.T.,
            Peterson,J.D., White,O., Nelson,W.C., Nierman,W.C., Van Aken,S.E.,
            Khouri,H.M., Fedorova,N.B., Forberger,H.A., Tran,B. and Fraser,C.M.
  TITLE     Direct Submission
  JOURNAL   Submitted (07-DEC-2005) The Institute for Genomic Research, 9712
            Medical Center Dr, Rockville, MD 20850, USA
  REMARK    Sequence update by submitter
REFERENCE   3  (bases 1 to 4383)
  AUTHORS   Nelson,K.E., Fouts,D.E., Mongodin,E.F., Ravel,J., DeBoy,R.T.,
            Rasko,D.A., Kolonay,J.F., Angiuoli,S., Gill,S.R., Paulsen,I.T.,
            Peterson,J.D., White,O., Nelson,W.C., Nierman,W.C., Van Aken,S.E.,
            Khouri,H.M., Fedorova,N.B., Forberger,H.A., Tran,B. and Fraser,C.M.
  TITLE     Direct Submission
  JOURNAL   Submitted (27-FEB-2004) The Institute for Genomic Research, 9712
            Medical Center Dr, Rockville, MD 20850, USA
COMMENT     REFSEQ INFORMATION: The reference sequence is identical to
            AE017262.2.
            
            On Jan 24, 2006 this sequence version replaced NC_002973.5.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000008285.1-RS_2025_01_30
            Annotation Date                   :: 01/30/2025 01:21:45
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,896
            CDSs (total)                      :: 2,807
            Genes (coding)                    :: 2,773
            CDSs (with protein)               :: 2,773
            Genes (RNA)                       :: 89
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 67
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 34
            CDSs (without protein)            :: 34
            Pseudo Genes (ambiguous residues) :: 0 of 34
            Pseudo Genes (frameshifted)       :: 20 of 34
            Pseudo Genes (incomplete)         :: 13 of 34
            Pseudo Genes (internal stop)      :: 8 of 34
            Pseudo Genes (multiple problems)  :: 6 of 34
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..4383
                     /organism="Listeria monocytogenes serotype 4b str. F2365"
                     /mol_type="genomic DNA"
                     /strain="4b F2365"
                     /serotype="4b"
                     /db_xref="taxon:265669"
     gene            1..1455
                     /locus_tag="LMOF2365_RS13945"
                     /old_locus_tag="LMOf2365_2751"
     CDS             1..1455
                     /locus_tag="LMOF2365_RS13945"
                     /old_locus_tag="LMOf2365_2751"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_466283.1"
                     /GO_function="GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="WP_003727629.1"
                     /translation="MEHNKLKPFPKDFLWGSASAAYQVEGAWDEDGKGPSVWDEFVRI
                     PGTTFKETNGDVAVDNYHRYKEDVALMAEQGLKAYRFSVAWSRVIPHGNGEVNEAGLK
                     FYDNLIDELLSYGIEPVVTLYHWDIPQGLQDEYGGWESRKVVEDFTNYAALLFKRFNG
                     RVKYWVTLNEQNVFISHGYKLAYHPPGVSDDKRMFAANHNANLANASAIAKFRELGTS
                     GKIGPSFAYGPSYSIDANPANVLASENSEEFNAHFWMDVYTWGEYPTATWNWLEEHGL
                     APEILPGDTELLKKGKPDFMGVNYYRSMTHAFNGKDGVGSGKMNTTGEKGTSEETGVP
                     GLYKNTNNPYLEKTNWDWDIDPTGLRIGLRRITNRYKLPIMITENGLGEYDSLTEDHK
                     IHDEYRIEYIRAHALAIQEAITDGVEMLGYCTWSFTDLLSWLNGYQKRYGFVYVDRDE
                     NDEKELKRYKKDSFYWYKKTIEANGANLVEEQGK"
     gene            1499..1801
                     /locus_tag="LMOF2365_RS13950"
                     /old_locus_tag="LMOf2365_2752"
     CDS             1499..1801
                     /locus_tag="LMOF2365_RS13950"
                     /old_locus_tag="LMOf2365_2752"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_466284.1"
                     /GO_function="GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA]"
                     /GO_process="GO:0008643 - carbohydrate transport [Evidence
                     IEA]; GO:0009401 - phosphoenolpyruvate-dependent sugar
                     phosphotransferase system [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="WP_003725315.1"
                     /translation="MKKILLVCAAGMSTSLLVTKMKAHATSIGEEIEIEALPVSEASS
                     VVDKMDIVMLGPQVRYQKPQVDELVQGRIPVIVIDMKDYGMLNGKAVLEKAFAEIG"
     gene            1834..3186
                     /locus_tag="LMOF2365_RS13955"
                     /old_locus_tag="LMOf2365_2753"
     CDS             1834..3186
                     /locus_tag="LMOF2365_RS13955"
                     /old_locus_tag="LMOf2365_2753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_466285.1"
                     /GO_component="GO:0016020 - membrane [Evidence IEA];
                     GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_function="GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA]"
                     /GO_process="GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="WP_003725316.1"
                     /translation="MSIMSKFEHGMERVLVPVANKLNSQRHIAAIRDAFILVFPLIMA
                     GSIITLINFAVLSPDGFIAKILFLGKIFPNLADAQAVFSPVMQGSTNIMAILIVFLVA
                     RNLAIFFKQDDLLCGLTSIGAFFIVYTPYTVVDNASYMTIKFLGAQGLFVAIIVAIIT
                     GEVFSRLARSPRLMIKMPDQVPPAVARSFKVLIPVIIITILFSVINYLITLIAPEGLN
                     DLVYTVIQAPLKDMGTNVFSVIIIGLVSNLLWVLGIHGPNTVAAIRDTIFTEPNLDNL
                     SYVAQHGSAWGAPYPATWAGLNDGFANYGGSGMTLGLLIAIFIASRRADYRDIAKLSL
                     APGIFNINEPVIFGLPIVLNPIMVIPFIITPAINTLIGYFFISTKLIPPVAYQVPWTT
                     PGPLIPFLGTGGNWLALLVGLLCLAVATVIYLPFVLVSNKIAASDAAMDKNATASTEQ
                     "
     gene            3198..4082
                     /gene="bglK"
                     /locus_tag="LMOF2365_RS13960"
                     /old_locus_tag="LMOf2365_2754"
     CDS             3198..4082
                     /gene="bglK"
                     /locus_tag="LMOF2365_RS13960"
                     /old_locus_tag="LMOf2365_2754"
                     /EC_number="2.7.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_466286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucoside kinase"
                     /protein_id="WP_010959095.1"
                     /translation="MKIAAFDIGGTALKMGVVLPHGEIILTKSAEISGSDGDQILAEM
                     TLFLTENKDVTGIAVSAPGYVNPKTGLITMGGAIRRFDNFNLKEWLEAETGIPVAIEN
                     DANCALLAEKWLGKGQNLDDFLCLTIGTGIGGGIFSNGALVRGGRFRAGEFGYMFSER
                     PGAFRPGKYTLNETTTMLVLRRQYAELTGRPLEEITGEEIFAKYDGHDAVSERLITEF
                     YTGICTGLYNLIYLFDPTHIFIGGGITSRPTFITELKHHMESFGLRDTIIETATHKNQ
                     AGLLGAVYHFLQEENRHE"
     gene            4075..4383
                     /locus_tag="LMOF2365_RS13965"
                     /old_locus_tag="LMOf2365_2755"
     CDS             4075..4383
                     /locus_tag="LMOF2365_RS13965"
                     /old_locus_tag="LMOf2365_2755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_466287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="WP_003725346.1"
                     /translation="MNEMETVIFGMISQVGSARSSYLEGLRAAREGNFEEAEAKLQEG
                     SETLANGHHEHHKLIQKEASGEKVEIQLLLIHAEDLLITTETLREVVTEFVHVYKKIS
                     "
ORIGIN      
        1 atggaacata ataagttgaa acctttccca aaagattttc tatggggatc agcttctgca
       61 gcgtaccaag tagaaggtgc ctgggatgag gatggcaaag gaccatctgt atgggatgaa
      121 tttgttcgta ttcctggaac aacattcaaa gaaacaaacg gagatgtagc ggtggataat
      181 taccatcgtt ataaagaaga tgtcgcacta atggctgaac agggcctaaa agcatatcgt
      241 ttctctgtcg catggagtcg cgttatcccg catggtaacg gggaagttaa cgaagcagga
      301 cttaaattct atgataattt gattgatgaa cttctttctt atggaattga gccagtcgtt
      361 acactttatc actgggatat tccgcaaggg cttcaagacg aatatggtgg atgggagtcg
      421 cgcaaagtcg tagaagattt cactaactac gctgcccttc tattcaaacg ctttaacggc
      481 cgagttaaat actgggtaac acttaatgaa cagaacgtat ttatctcaca cggttacaaa
      541 ttagcgtatc acccacctgg cgtttctgac gacaagcgta tgtttgcggc aaatcacaat
      601 gcgaacttgg cgaatgcttc tgcaattgct aaattccgcg agctaggtac atccggaaaa
      661 attggaccaa gttttgctta tggaccaagt tactccatcg atgctaaccc agcaaatgta
      721 ttagcttctg aaaactccga agaattcaat gcccatttct ggatggatgt ttacacatgg
      781 ggtgaatatc cgactgctac ttggaactgg ctagaagagc acggtcttgc accggaaatc
      841 ttaccaggcg atacggagct tctgaaaaaa ggaaaacctg atttcatggg agttaactat
      901 taccgctcaa tgactcatgc atttaatggg aaagacggcg ttggttctgg gaaaatgaat
      961 acaactggcg aaaaaggcac ttccgaggaa actggtgtac cggggttata caaaaacacc
     1021 aataatccat acttagagaa aacgaattgg gactgggata ttgatccaac tggcttgcgc
     1081 attggcttac gtagaattac taaccgctat aaattaccaa tcatgattac agaaaatggt
     1141 cttggtgagt atgatagctt gacggaagac cataaaatcc atgatgagta ccgaattgaa
     1201 tacattcgcg cgcatgctct agcaatccaa gaagcaatca cggacggcgt agagatgctc
     1261 ggttactgca cttggagctt cacagattta ctaagctggt taaacggcta ccaaaaacgt
     1321 tacggtttcg tatatgtaga ccgcgacgaa aacgatgaaa aagaattaaa acgctataaa
     1381 aaagatagtt tttactggta taaaaagacc atcgaagcaa acggagctaa tttagtagaa
     1441 gaacagggca aataagcctt gttctctctg cttcaaccat tttgggaggg aaattttaat
     1501 gaaaaaaata ttacttgtat gtgcggccgg aatgtcgaca agcttactcg ttactaaaat
     1561 gaaagcgcac gcaacctcta ttggggaaga aattgaaatc gaagcattac cagtatcaga
     1621 agctagcagc gttgtggaca aaatggatat cgtgatgctt ggacctcaag tccgttacca
     1681 aaaaccgcaa gtagatgaac tcgtacaggg tcgcattcct gttattgtta tcgatatgaa
     1741 agattatggt atgttaaacg ggaaagccgt tcttgaaaaa gctttcgcgg agattggtta
     1801 agggagattc attcaaaata gggaggtttt aaaatgagta taatgtcaaa atttgaacac
     1861 ggcatggaac gtgttttagt accagttgcg aataaattga actcgcagcg ccatattgca
     1921 gcaattcgtg atgcatttat tttagttttc ccattaatta tggctggttc aattatcact
     1981 ttgattaact tcgcagtatt atcaccagat ggctttattg caaaaatctt attcctaggg
     2041 aaaattttcc ctaatttagc cgatgcacag gctgtatttt cgccggtaat gcaaggttcg
     2101 accaatatta tggccattct gatcgtattc ttagtcgcac ggaatctcgc catcttcttt
     2161 aaacaggatg atttgctctg tggacttacc tcgataggtg cattctttat cgtgtataca
     2221 ccttacacag tagttgacaa tgcatcttac atgacaatca aattcttagg cgcacaaggt
     2281 cttttcgttg ctattattgt agcgattatt actggggaag tatttagccg tctagctaga
     2341 tcccctcgtt taatgatcaa aatgcctgac caagtaccac cagcagttgc tcgttctttt
     2401 aaagtattaa ttccagttat catcatcact attcttttct ctgtcattaa ctacttaatc
     2461 actttaatcg ctccagaagg tttaaacgac cttgtttaca cagttattca agcgccactt
     2521 aaagacatgg gaactaacgt attctctgta attatcatcg ggcttgtttc taacttactt
     2581 tgggttcttg gtattcacgg gcctaacact gttgcggcta ttcgtgacac catcttcact
     2641 gaaccaaact tagacaactt atcttacgta gcacagcacg gttctgcttg gggagctcca
     2701 tacccagcaa catgggctgg cctaaatgac ggatttgcaa actacggcgg atctggtatg
     2761 actctaggtt tactgattgc tatctttatc gcttctcgtc gtgcagacta ccgagatatc
     2821 gcgaaacttt ctcttgcacc agggattttc aacatcaatg aaccagttat tttcggttta
     2881 ccaatcgtat taaacccaat tatggttatt cctttcatca ttacaccagc aatcaataca
     2941 ttaattggtt acttctttat ctcaacaaaa cttattccac ctgtcgccta tcaagtgcct
     3001 tggacaactc caggaccact gattccattt cttggtacag gaggaaactg gctcgcgctt
     3061 ctggtcggct tgctctgtct agccgtcgcg acagtcattt atctaccatt cgtacttgta
     3121 tctaacaaaa ttgccgcgag tgatgctgca atggacaaaa atgcaacagc ctcaacggaa
     3181 caataggatg tgacaaaatg aaaattgcag cttttgatat cggtggaacg gcccttaaaa
     3241 tgggggtcgt tttgccgcat ggtgaaatta tactaacaaa atccgccgaa atcagcggta
     3301 gcgacggcga ccaaatttta gcagaaatga cattatttct tactgaaaat aaggatgtaa
     3361 ccggaattgc agtcagcgcg cctggctatg tgaacccaaa aaccggactt attacaatgg
     3421 gcggcgctat ccgtagattt gataacttta atttgaaaga atggcttgaa gcagaaaccg
     3481 gaattcctgt tgccattgaa aatgacgcca attgcgccct tcttgccgaa aaatggcttg
     3541 gtaaaggaca aaatttggat gattttcttt gtctaacaat cggaactggg attggcggcg
     3601 gaattttttc caatggcgca ttagttcgtg gtggtcgttt ccgggctggc gagtttggtt
     3661 atatgtttag cgaacgtcca ggggctttcc gtcctggcaa atatacgcta aatgagacta
     3721 ccacaatgct tgttcttcgc agacaatacg cggaacttac tgggcgccct ttggaagaga
     3781 ttactggcga agaaattttt gctaagtatg atggacacga cgccgtctca gaacgtctta
     3841 ttactgagtt ttatactgga atttgtacgg ggctttataa tttaatttac ttgttcgatc
     3901 caacgcatat ctttattggt ggtggaatta caagtcgccc tacttttatc acggagctaa
     3961 agcatcatat ggagagcttt gggctgcgtg acacaattat cgaaacagca acacataaaa
     4021 accaagctgg cctactcggc gcagtgtatc actttttaca ggaggaaaat agacatgaat
     4081 gaaatggaaa cagtaatttt tggcatgatt agccaagttg gttctgcgag aagcagttac
     4141 ttagaagggc ttcgtgcggc tcgtgaaggc aatttcgagg aagcagaagc aaaactacaa
     4201 gaaggtagcg aaactcttgc aaatgggcac cacgagcatc ataagctaat ccaaaaagaa
     4261 gcttccggtg aaaaagtgga aatccaatta cttttaatcc atgcggaaga cttactcatc
     4321 acaaccgaaa ctttaagaga agttgtcact gagttcgtgc atgtatataa aaaaataagc
     4381 taa
//
