LOCUS       NC_011593               7693 bp    DNA     linear   CON 01-JUL-2024
DEFINITION  Bifidobacterium longum subsp. infantis ATCC 15697 = JCM 1222 = DSM
            20088, complete sequence.
ACCESSION   NC_011593 REGION: 395169..402861
VERSION     NC_011593.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN02598380
            Assembly: GCF_000020425.1
KEYWORDS    RefSeq.
SOURCE      Bifidobacterium longum subsp. infantis ATCC 15697 = JCM 1222 = DSM
            20088
  ORGANISM  Bifidobacterium longum subsp. infantis ATCC 15697 = JCM 1222 = DSM
            20088
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Bifidobacteriales; Bifidobacteriaceae; Bifidobacterium.
REFERENCE   1  (bases 1 to 7693)
  AUTHORS   Sela,D.A., Chapman,J., Adeuya,A., Kim,J.H., Chen,F.,
            Whitehead,T.R., Lapidus,A., Rokhsar,D.S., Lebrilla,C.B.,
            German,J.B., Price,N.P., Richardson,P.M. and Mills,D.A.
  TITLE     The genome sequence of Bifidobacterium longum subsp. infantis
            reveals adaptations for milk utilization within the infant
            microbiome
  JOURNAL   Proc Natl Acad Sci U S A 105 (48), 18964-18969 (2008)
   PUBMED   19033196
REFERENCE   2  (bases 1 to 7693)
  AUTHORS   Lucas,S., Copeland,A., Lapidus,A., Barry,K., Detter,J.C., Glavina
            del Rio,T., Dalin,E., Tice,H., Goltsman,E., Pitluck,S., Schmutz,J.,
            Larimer,F., Land,M., Hauser,L., Kyrpides,N., Mikhailova,N.,
            Sela,D.A., Chapman,J., Adeuya,A., Kim,J.H., Chen,F.,
            Whitehead,T.R., Rokhsar,D.S., Lebrilla,C.B., German,J.B.,
            Price,N.P., Mills,D.A. and Richardson,P.M.
  CONSRTM   US DOE Joint Genome Institute
  TITLE     Direct Submission
  JOURNAL   Submitted (28-MAY-2008) US DOE Joint Genome Institute, 2800
            Mitchell Drive B100, Walnut Creek, CA 94598-1698, USA
COMMENT     REFSEQ INFORMATION: The reference sequence is identical to
            CP001095.1.
            URL -- http://www.jgi.doe.gov
            JGI Project ID: 40002686
            Source DNA available from David Mills (damills@ucdavis.edu)
            Bacteria available from ATCC: ATCC 15697
            Contacts: David Mills (damills@ucdavis.edu)
                      David Bruce (microbe@cuba.jgi-psf.org)
            Quality assurance done by JGI-Stanford
            Annotation done by JGI-ORNL and JGI-PGF
            Finishing done by JGI-PGF
            Finished microbial genomes have been curated to close all gaps with
            greater than 98% coverage of at least two independent clones. Each
            base pair has a minimum q (quality) value of 30 and the total error
            rate is less than one per 50000.
            The JGI and collaborators endorse the principles for the
            distribution and use of large scale sequencing data adopted by the
            larger genome sequencing community and urge users of this data to
            follow them. it is our intention to publish the work of this
            project in a timely fashion and we welcome collaborative
            interaction on the project and analysis.
            (http://www.genome.gov/page.cfm?pageID=10506376).
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000020425.1-RS_2024_07_01
            Annotation Date                   :: 07/01/2024 00:54:16
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,672
            CDSs (total)                      :: 2,572
            Genes (coding)                    :: 2,465
            CDSs (with protein)               :: 2,465
            Genes (RNA)                       :: 100
            rRNAs                             :: 4, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 84
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 107
            CDSs (without protein)            :: 107
            Pseudo Genes (ambiguous residues) :: 0 of 107
            Pseudo Genes (frameshifted)       :: 33 of 107
            Pseudo Genes (incomplete)         :: 87 of 107
            Pseudo Genes (internal stop)      :: 7 of 107
            Pseudo Genes (multiple problems)  :: 20 of 107
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..7693
                     /organism="Bifidobacterium longum subsp. infantis ATCC
                     15697 = JCM 1222 = DSM 20088"
                     /mol_type="genomic DNA"
                     /strain="ATCC 15697"
                     /sub_species="infantis"
                     /culture_collection="ATCC:15697"
                     /type_material="type strain of Bifidobacterium infantis"
                     /db_xref="taxon:391904"
     gene            1..912
                     /locus_tag="BLON_RS01780"
                     /old_locus_tag="Blon_0341"
     CDS             1..912
                     /locus_tag="BLON_RS01780"
                     /old_locus_tag="Blon_0341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013140198.1"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]; GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="WP_012576772.1"
                     /translation="MTNATAQPDTSVMRKPKRQYIGILYCLPYVVVFLFGMIVPMFYA
                     LYLSFFKQSLLGGTTFAGFDNFIRAFKDEALWGGFRNVLIYAAIQIPMNLILSLVAAL
                     VLDSQRIRHIAVPRILLFLPYAVPGVIAALMWGYIYGDKYGLFGQIAGMFGVAAPNML
                     SKQLMLFAIANICTWCFLGYNMLIYYSALIGIPNDLYESARIDGASELRIAWSVKIPQ
                     IKSTIVMTVLFSVIGTLQLFNEPNILRTSAPDVINSSYTPNIYTYNLAFNGQNVNYAA
                     AVSLVIGIIVMALVAVVKIIGNKWENK"
     gene            912..1889
                     /locus_tag="BLON_RS01785"
                     /old_locus_tag="Blon_0342"
     CDS             912..1889
                     /locus_tag="BLON_RS01785"
                     /old_locus_tag="Blon_0342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004221042.1"
                     /GO_process="GO:0008643 - carbohydrate transport [Evidence
                     IEA]; GO:0055085 - transmembrane transport [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="WP_012576773.1"
                     /translation="MSEAIARPRSKSLQRRDAKLALKASKHYKRMQQREPAPKLTGKQ
                     RVLNWLLHIIMAVMVIYCLVPLLWVVFSSTKTSEGIFSSFGLWFDDKNVFWQNVQDTF
                     AYQHGVYTRWLFNTIMYAVVAGVGATIIATFAGYAIATMRFPGRNALLAVTLAFMSIP
                     STVITVPLFLMYSKIGLVGTPWAVIIPQLATPFGLYLMIIYAQTSIPVSLIEAAKLDG
                     ANTWTIFWKVGFPLLSPGFVTVLLFTLVGVWNNYFLPLIMLTNTNDYPLTVGLNMWLK
                     MGAQGTSDGQVPNNLIITGSLIAVVPLIIAFMFLQKYWQSGLAAGSVKQ"
     gene            2004..3392
                     /locus_tag="BLON_RS01790"
                     /old_locus_tag="Blon_0343"
     CDS             2004..3392
                     /locus_tag="BLON_RS01790"
                     /old_locus_tag="Blon_0343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012578460.1"
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]; GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="WP_014484561.1"
                     /translation="MKKSIRLIAAVAALAMTAGAAACGSGTSQKNNKADVSLNDINSA
                     LTDTSKTTDLTVWAYSAKQIEGPVKAFQERYPHIKINFVNTGAASDHFTKFQNVVSAN
                     KGVPDVVQMSISEYEQYAVSGALLNFESDEIEKAWGTQYAQAAWKNVHFGGGLYGTPQ
                     DAAPLALYVRKDILDEHGLKVPTTWQEFYDEGVKLHKQDPSKYMGFISSSDTSLFGVL
                     RTVGAKPWTVKDTTNIDFSLTTGRVAEFIKFIQKCLDDGVLRAAATGTDEFNREVNDG
                     VYATRLEGCWQGNIYKDQNPSLKGKMVVAHPLAWGNDGESYQSESTGSMFSVSSATPK
                     DKQAAALAFIQWVNGSKDGVSEFLTANKGNYFMASNYYQKDKSKRDQQETDGYFANTN
                     VNEIYFESMDKVNMDWDYIPFPAQLTVAFGDTVAPALTGKGDLLTAFTKLQDNLKSYA
                     EDNGFKVTTDAD"
     gene            3482..>4057
                     /locus_tag="BLON_RS01795"
                     /old_locus_tag="Blon_0344"
                     /pseudo
     CDS             3482..>4057
                     /locus_tag="BLON_RS01795"
                     /old_locus_tag="Blon_0344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013399559.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="fuconate dehydratase"
     gene            4368..5591
                     /locus_tag="BLON_RS01800"
                     /old_locus_tag="Blon_0345"
     CDS             4368..5591
                     /locus_tag="BLON_RS01800"
                     /old_locus_tag="Blon_0345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012576776.1"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="WP_012576776.1"
                     /translation="MSKIINYSEVLESKRLMVGVLSVSFLLSAGNAISGTIPAMEEAF
                     SNISKANIETLTTIPTAGIMLGTVLSGVFSNYLGKKKSVLAGLIIALVGGVIPAFLPQ
                     YWPIFISRFLFGVGMGIFNPLSVSYITDLYVGDRQRSLLGYRNAVSNLGDTIMLFVAG
                     ILITFGWNITYLVFFALLIPIVLIILFVPKEFDNFDIRNSALDENGQISDSVSDVKPS
                     TNLKVIEVGVVFMVITMLYNAIPLKFASYIVTEHIGTASTATWIFSFLVLAGIFSGVL
                     FEKISKVFKRLTVFVFEIVIGVAYITIAFTYNIPLLTALVLISGFGWGIINPALTARL
                     VDVSPINSMNLSTSIIVIFISVGSLISPYFFAMFAGLFGNDSAAFAIVVGGALYVVMA
                     VLDFIKIKKNKELSI"
     gene            5669..7693
                     /locus_tag="BLON_RS01805"
                     /old_locus_tag="Blon_0346"
     CDS             5669..7693
                     /locus_tag="BLON_RS01805"
                     /old_locus_tag="Blon_0346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012576777.1"
                     /GO_function="GO:0004565 - beta-galactosidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase trimerization
                     domain-containing protein"
                     /protein_id="WP_012576777.1"
                     /translation="MMSTATGFPNRQINLDFHTSPYVEHVADDFDAEEFAERLHRSHV
                     NSITCFARDHHGYLFYPSKRHPELVHPHLSDRNLLLEQIDACHKRGIRVPVYTSVGWD
                     GYSALNHPEWLARDPQDNVINGCPSVPKPNFYDSLCLNSNYRAYLIDHLNDIIDSLGP
                     DRVDGLFLDIFSLVPCDCPRCREQMERHGFDHTDIRQRERYSAILLDEFRREVHDLVD
                     DRVPGATLFFNGGHIGPSNKTSLDTFTHLEVESLPSGFWGYDNFPIVMRYVRNLGKPV
                     VGMTGKFHTAWGDFHSLKNEDAMEYECFQMLTMGAGCSIGDQLHPRGGLSDATYDLIG
                     RVYSQVEALEPYTLDTDTMADIAVMTPEREWNMDSALSDSLIGANRMLTELGCQFDII
                     DPDMDFTRYGLIVLPDEIVSSPELQRKLLDYVHGGGKVVGTYMSMDNGCDETNPLYGN
                     RMLGDSYWDRDFIMPNDEVGARLPKEEFVMYERGARVRTAGSRVLLDSVEPYFNREGR
                     YFCSHLHAPSTGRVGFPAATRYGDVVYFSHPLFRIYKDFAPSWVKAIFADVLDLLMPR
                     QLVRKEDGHTVSGLEVQLRRSGSRNSLMLHCLYYPCKKSAANLYTIDEKVPLFDQRVR
                     VYVGDAEIESVRAIRQGEVISERDYTVADGYVDLNIPKIDGYEIIELSLK"
ORIGIN      
        1 atgacaaatg caacggcgca accggatact tccgtgatgc gcaagccgaa gcgccaatac
       61 ataggcatat tgtattgtct tccatacgtg gtggtcttcc tgttcggcat gatcgtcccg
      121 atgttctacg cgctttatct cagcttcttc aagcagtccc ttctcggtgg caccacattc
      181 gcgggcttcg acaacttcat ccgagcgttc aaggatgagg ctttgtgggg cggctttagg
      241 aacgtgctga tttacgcggc gatccagatt ccgatgaatc tgattctgtc cctcgtggcg
      301 gcgctcgtct tggactccca gaggatccgc catatcgcgg tgccgcgaat cctgctgttc
      361 ctgccttatg ccgtcccagg cgtcatcgcg gcgctgatgt ggggatacat ttacggcgat
      421 aagtatggtc tttttggaca aatcgccggt atgtttggcg tagcggctcc taatatgttg
      481 tcgaagcagc tcatgttgtt cgccatcgcg aacatctgca cttggtgctt ccttggctat
      541 aacatgctga tttattattc tgcactgatc ggcattccga acgacctgta cgaatctgcc
      601 cgtattgacg gcgcttcgga gctgcgcatc gcttggtccg tgaagatccc ccagattaag
      661 agcaccatcg tgatgacggt cctcttctct gtgatcggca cgctccagct gttcaacgaa
      721 ccgaacatct tgcgtacttc cgccccggac gtgatcaaca gcagctatac gccgaacatc
      781 tacacctaca acctcgcatt caatggccag aacgtcaact atgccgctgc cgtctctctg
      841 gtcatcggca tcatcgtcat ggccttggtc gccgtcgtta agatcatcgg caacaagtgg
      901 gagaacaagt gatgagtgaa gcaatcgcaa gaccgcgttc caagtcgctg cagcgcagag
      961 acgccaaact ggcgctcaag gcaagcaagc attacaagcg catgcagcag cgtgagccgg
     1021 ctccgaagct gaccggcaag cagcgtgtgc tcaactggct gctgcacatc attatggctg
     1081 tgatggtcat ctactgcctc gtgccgctgc tgtgggtcgt cttctcttcc acaaagacca
     1141 gtgagggcat cttcagctct ttcggcctgt ggttcgatga caagaatgtg ttctggcaga
     1201 acgtgcagga tacgtttgct tatcagcatg gtgtctacac tcgttggctg ttcaatacga
     1261 tcatgtacgc agtggtagca ggtgttggtg caaccatcat tgccactttc gctgggtatg
     1321 ccatcgccac catgcgattc cctggacgta acgccctgct ggccgtcact ctggcattca
     1381 tgtcaattcc ttctacggtg atcaccgtgc cgctgttcct catgtattcg aagatcgggc
     1441 tggtcggcac tccgtgggcc gtgattattc cgcagcttgc cacgccgttc ggcctgtatc
     1501 tgatgatcat ctatgcgcag acctcgattc cggtctcgct gatcgaagcc gcgaaactgg
     1561 acggtgcaaa cacttggacc atcttctgga aggtcggttt cccgctgctg tctccaggtt
     1621 tcgtcaccgt actgctgttc acgctggtcg gtgtttggaa caactacttc ctgccgctga
     1681 tcatgcttac gaataccaac gactacccgt tgacggtcgg tctgaacatg tggctgaaga
     1741 tgggtgccca gggaacttca gacggtcagg ttccgaacaa cctcatcatc acgggctcgc
     1801 ttatcgcagt tgttccgttg atcatcgcat tcatgttcct gcaaaagtac tggcagtctg
     1861 gcctcgcggc cggctctgtc aagcagtgaa cccttggccg cacggtccct acgatcacac
     1921 attcgttgcc ttggcgaccg tgcggcatcc atctgtttga aaaaacaaca agatagtaat
     1981 tcatgacaca caaaggagta atcatgaaga agagtattcg ccttatagct gctgtagcag
     2041 cattggccat gactgctgga gcggctgcct gcggctctgg tacttcgcag aaaaacaata
     2101 aggctgatgt atctttgaat gatattaatt ccgctttaac cgatacctca aaaacaacgg
     2161 atttgacggt atgggcatat tcggctaagc aaatcgaagg tccggtcaag gctttccagg
     2221 agagatatcc tcatatcaaa attaacttcg tcaatacagg cgctgcatct gatcatttca
     2281 cgaaattcca aaacgttgtt tctgccaata aaggcgttcc ggatgtagta caaatgtcga
     2341 tcagcgaata tgagcagtat gcggttagcg gagcgctcct aaactttgaa tcagatgaaa
     2401 ttgaaaaggc ttggggaacg cagtatgcac aagcagcgtg gaaaaatgtg cactttggtg
     2461 gtggactgta tggcaccccg caggatgctg cacctttggc cctatatgtt cgaaaggaca
     2521 ttctcgatga gcatgggctg aaagttccca ctacttggca agaattctat gatgaaggag
     2581 tcaagcttca taagcaggat ccaagtaagt acatggggtt catttcctct agcgatactt
     2641 ctttgttcgg tgtattacgt accgttggcg caaagccttg gacggtaaag gatacaacga
     2701 atattgattt ctcgctaacc acaggtcggg tggcggagtt cattaaattc attcagaagt
     2761 gcctggatga tggagttctt cgtgctgctg ctaccggtac agatgaattt aatcgtgaag
     2821 tcaatgatgg cgtatatgca accagattgg aagggtgctg gcaaggcaat atctacaagg
     2881 atcagaatcc ttctttgaag ggtaagatgg tcgtcgccca tcctttggca tggggtaatg
     2941 atggagaatc gtatcagtct gagtctactg gctccatgtt ctctgtttca tcagctacac
     3001 caaaggataa gcaagcagcg gcattggctt tcattcagtg ggtcaatggc agcaaggatg
     3061 gagtttctga gttcttgacg gcaaataaag gtaattactt tatggcctct aactattatc
     3121 agaaggataa gagcaagcga gatcagcaag aaacagacgg atatttcgca aatactaatg
     3181 tgaatgagat ctattttgag tctatggata aagtgaacat ggactgggat tatattccat
     3241 tccctgcgca gctcacagtt gcgtttggtg ataccgtagc tcctgctctg acaggtaagg
     3301 gagacttgtt gactgcattt accaagttgc aggataacct taagtcttac gccgaggata
     3361 acggttttaa agtcaccact gacgcagact gataaccgcc cataatatgt tgttgcgggg
     3421 aggatggctg gtctgccgtc ctcccttttt gagattaaac atctttccaa ggaagcgcac
     3481 tgtgagcgtt atcaccaaag tcaccacgta tgatttccgg ttcccgacat cggccacgtt
     3541 ctcgggttcc gatgccatga accctgatcc ggattactcc tccgcctacg tcgtcgtctc
     3601 cacggatgcc ggtgactccg gcaatggatt cgtcttcacc atcggccgtg gcaacgatgt
     3661 cgtcgtccgg gccatcgact ccatgtccga gacccttatc ggtcgtaacg tcgaggaact
     3721 gctcgacaac atgcgtctcg catgggatct gttcgtgcgc gattcgcagc tgcgctggct
     3781 cggccctgag aagggcgtcg agcacatggc catcggcgcc gtgctttcgg ccctgtggga
     3841 cctcaaggcc aagcgcgccg gcaagccgct ctggctgctc ctttccgaga tggagcctga
     3901 agagctcgtc gcgacgcttg acttccgtta cctgaccgac gccctcactg cgcaggaggc
     3961 catcgatatc ctgcgcgccg cccaggaagg caaggcggag cgtatcgccc acctcaagga
     4021 agtcggttac ccgggatatt cgaccgccgc cggatggcgt gcggtcggca agatacagag
     4081 aagtatgtgc aagatacgga gaagtatatg aatgcgataa gtattgcgct tccattccga
     4141 cagtggaatt atttgcgttg tctgtctaat gtgattcgac cagatgggac gtcgatagtc
     4201 ggtcctattc cgtgtgctgg tgatgtggag ttgatcatcc attagtgcct catatgcata
     4261 tcggctatca atgtgggtag gtgaaggaga tatacgcaag aatatctaag atataagttc
     4321 aaattcttaa tcttttcaat gttgatttat atgtgtctgg agtgataatg tcaaaaataa
     4381 ttaattatag tgaagtactg gaatccaaac gtctgatggt tggcgtcttg tcggtgtctt
     4441 tcttattgtc cgctggtaat gctattagcg gaacgattcc cgcgatggaa gaagcgttct
     4501 cgaatatttc gaaagccaat attgagacac taacgaccat accgacagcg ggaattatgc
     4561 tcggaaccgt cctctcgggt gttttctcga attatctagg aaaaaagaaa tccgtgctcg
     4621 cgggtttgat tatcgctttg gttggcggtg ttatccccgc gttcctgcct caatactggc
     4681 caatctttat ttcgcgtttc ctctttggcg tgggcatggg tatctttaat ccgctttctg
     4741 tgtcctatat caccgatctg tatgtggggg atcgtcagcg tagtcttctt ggataccgca
     4801 atgcggttag caatctgggt gataccatca tgcttttcgt tgctggtatc ttgattacct
     4861 ttggttggaa tatcacctat ctggtcttct tcgccttgct gataccgatt gttttaataa
     4921 ttttgttcgt tccaaaggaa ttcgataatt tcgatatcag gaacagtgct ctggatgaga
     4981 atggtcagat tagtgacagt gtgtctgatg tcaaaccatc tacgaatctc aaggtgatcg
     5041 aggttggcgt tgtatttatg gttatcacta tgctatataa cgcgatcccg ctgaaatttg
     5101 cgagctatat tgtcacggag catatcggca ctgcctcgac cgccacatgg atcttcagct
     5161 tcctggtctt ggcgggcatt ttctccggcg tgctgttcga gaagatttcc aaggttttca
     5221 agcgtttgac ggtgttcgta ttcgagattg ttattggcgt cgcctatatc acgattgcgt
     5281 tcacctacaa cattccgttg ctgacggctt tggtgttgat ctctggcttt ggttggggta
     5341 ttatcaaccc ggcattgaca gcgcgactcg tagatgtgtc gccgattaac tctatgaatc
     5401 tgagtacttc aataattgtt atctttatca gtgttggttc tcttatttcc ccgtacttct
     5461 tcgcaatgtt cgcgggcttg ttcggtaacg attcggctgc gttcgctatt gttgtcggtg
     5521 gtgccctgta tgtggtcatg gccgtgcttg atttcatcaa aataaagaag aacaaggagc
     5581 tgagcatctg attgattcgt ggttggaatc gttgacgacg attccaaccc ggcaatcgga
     5641 agccgttcca tcgcaacaaa ggagttcaat gatgtccacc gcaactggtt tcccaaatcg
     5701 ccagattaat ctggattttc ataccagtcc ttacgttgag catgtcgccg acgatttcga
     5761 cgccgaggaa ttcgcggaac gtctgcatcg ttctcacgta aactcgataa cctgtttcgc
     5821 ccgtgaccat cacggctacc tgttctatcc ctcgaagcgc catcccgagc tcgtgcatcc
     5881 gcacctgtcg gacaggaatc tcctgcttga gcagatagac gcctgccaca agcgcggcat
     5941 ccgcgtcccc gtctacacga gcgtgggctg ggacgggtac agcgcgctca accatcccga
     6001 gtggcttgcc cgggaccccc aagacaatgt aataaacgga tgcccgtcgg ttccaaagcc
     6061 gaacttctac gattcgctgt gtctgaacag caattacagg gcctatctca tcgatcacct
     6121 caacgacatc atcgacagcc tcggcccgga ccgcgtcgac gggctcttcc tggatatctt
     6181 ctccttggtg ccgtgcgact gcccgcgttg ccgggagcag atggagcgtc atggctttga
     6241 ccacaccgat atccgccagc gggaacggta ttcggccatc ctgcttgacg agttccgtcg
     6301 tgaggtccac gacctcgtgg atgatcgggt gcctggcgcg actctgttct tcaacggtgg
     6361 gcatatcggc ccctcgaaca agacctcgtt ggacacgttc acccatctgg aggtcgagag
     6421 cctgccaagt ggtttttggg gctacgacaa cttcccaatc gtgatgaggt acgtgcgcaa
     6481 tctcggcaaa cccgtggtcg gcatgacggg caagttccac acggcttggg gtgatttcca
     6541 ttcgctgaag aacgaggacg cgatggaata cgagtgcttc cagatgctga cgatgggcgc
     6601 cggctgctcc atcggggacc agctccatcc gagaggcggg ttgtccgacg ccacctatga
     6661 tctgatcgga cgggtctact cccaggtgga ggccctcgaa ccgtacacgc tggataccga
     6721 cacgatggcg gacatagcgg tcatgacgcc ggaacgcgaa tggaacatgg acagcgcgct
     6781 gtccgattcg ttgatcggcg ccaaccggat gctcacggaa ctgggatgcc agttcgacat
     6841 catcgatccg gacatggact tcacgcggta cgggctcatc gtccttcccg acgagatcgt
     6901 gtcctccccc gaactccaac ggaagctgct ggactacgtg catggcggcg gcaaggtcgt
     6961 cggcacgtac atgtcgatgg acaacggctg cgacgagacc aatccgctgt acggcaacag
     7021 gatgctgggc gattcctatt gggatcggga tttcatcatg ccgaacgacg aggtcggggc
     7081 gcgtctgccc aaagaggagt tcgtcatgta cgagcgtggc gcgcgggtga ggacggcggg
     7141 atcgcgggtg ctgctggatt cggtcgaacc ctacttcaat cgtgagggga ggtatttctg
     7201 ctcccacctg catgccccct cgaccgggag ggtcgggttc cccgcggcga cgcggtacgg
     7261 cgacgtcgtc tatttctccc acccgttgtt ccgcatctac aaggatttcg ccccgtcgtg
     7321 ggtcaaggcg atattcgccg acgtcctcga tctgctgatg ccgaggcagc tggtgcgcaa
     7381 ggaggacggg catacggtca gcgggctgga ggtgcagctg cgccgttcgg gttcgcgcaa
     7441 ttcgttgatg ctgcattgcc tgtactaccc ctgcaagaag tcggccgcca acctgtacac
     7501 gatcgacgag aaggttccgc tgttcgacca gcgcgtgcgc gtgtatgtgg gcgacgccga
     7561 gatcgagtcg gtccgcgcga tccgtcaggg cgaggtgatc tccgaacggg actacaccgt
     7621 ggccgacggg tatgtcgatc tgaacattcc caagatcgac gggtacgaga tcatcgagtt
     7681 gtcgctgaaa tga
//
