LOCUS       NC_012034              23876 bp    DNA     linear   CON 13-DEC-2024
DEFINITION  Caldicellulosiruptor bescii DSM 6725, complete sequence.
ACCESSION   NC_012034 REGION: 212375..236250
VERSION     NC_012034.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN02598462
            Assembly: GCF_000022325.1
KEYWORDS    RefSeq.
SOURCE      Caldicellulosiruptor bescii DSM 6725
  ORGANISM  Caldicellulosiruptor bescii DSM 6725
            Bacteria; Bacillati; Bacillota; Bacillota incertae sedis;
            Caldicellulosiruptorales; Caldicellulosiruptoraceae;
            Caldicellulosiruptor.
REFERENCE   1  (bases 1 to 23876)
  AUTHORS   Lucas,S., Copeland,A., Lapidus,A., Glavina del Rio,T., Tice,H.,
            Bruce,D., Goodwin,L., Pitluck,S., Sims,D., Meincke,L., Brettin,T.,
            Detter,J.C., Han,C., Larimer,F., Land,M., Hauser,L., Kyrpides,N.,
            Ovchinnikova,G., Kataeva,I. and Adams,M.W.W.
  CONSRTM   US DOE Joint Genome Institute
  TITLE     Complete sequence of chromosome of Caldicellulosiruptor becscii DSM
            6725
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 23876)
  AUTHORS   Lucas,S., Copeland,A., Lapidus,A., Glavina del Rio,T., Tice,H.,
            Bruce,D., Goodwin,L., Pitluck,S., Sims,D., Meincke,L., Brettin,T.,
            Detter,J.C., Han,C., Larimer,F., Land,M., Hauser,L., Kyrpides,N.,
            Ovchinnikova,G., Kataeva,I. and Adams,M.W.W.
  CONSRTM   US DOE Joint Genome Institute
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JAN-2009) US DOE Joint Genome Institute, 2800
            Mitchell Drive B310, Walnut Creek, CA 94598-1698, USA
COMMENT     REFSEQ INFORMATION: The reference sequence is identical to
            CP001393.1.
            URL -- http://www.jgi.doe.gov
            JGI Project ID: 4084710
            Source DNA available from Michael Adams (adams@bmb.uga.edu)
            Bacteria available from DSMZ: DSM 6725
            Contacts: Michael Adams (adams@bmb.uga.edu)
                 David Bruce (microbe@cuba.jgi-psf.org)
            Annotation done by JGI-ORNL and JGI-PGF
            Finishing done by JGI-LANL
            Finished microbial genomes have been curated to close all gaps with
            greater than 98% coverage of at least two independent clones. Each
            base pair has a minimum q (quality) value of 30 and the total error
            rate is less than one per 50000.
            The JGI and collaborators endorse the principles for the
            distribution and use of large scale sequencing data adopted by the
            larger genome sequencing community and urge users of this data to
            follow them. it is our intention to publish the work of this
            project in a timely fashion and we welcome collaborative
            interaction on the project and analysis.
            (http://www.genome.gov/page.cfm?pageID=10506376)
            Meta information:
             Organism display name: Caldicelulosiruptor becscii Z-1320, DSM
            6725
             Culture Collection IDs: DSM 6725
             GOLD ID: Gi03121 http://genomesonline.org/GOLD_CARDS/Gi03121.html
             Sequencing Platforms: Sanger, 454
             Phenotypes: Thermoacidophile, Cellulose degrader
             Diseases: None
             Habitat: Fresh water, Hot spring
             Oxygen Requirement: Anaerobe
             Temperature Range: Thermophile
             Biotic Relationship: Free living
             Isolation: Hot spring on the Kamchatka peninsula in Russia.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000022325.1-RS_2024_12_13
            Annotation Date                   :: 12/13/2024 12:57:17
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,844
            CDSs (total)                      :: 2,783
            Genes (coding)                    :: 2,660
            CDSs (with protein)               :: 2,660
            Genes (RNA)                       :: 61
            rRNAs                             :: 3, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 3, 3 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 123
            CDSs (without protein)            :: 123
            Pseudo Genes (ambiguous residues) :: 0 of 123
            Pseudo Genes (frameshifted)       :: 71 of 123
            Pseudo Genes (incomplete)         :: 66 of 123
            Pseudo Genes (internal stop)      :: 36 of 123
            Pseudo Genes (multiple problems)  :: 46 of 123
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..23876
                     /organism="Caldicellulosiruptor bescii DSM 6725"
                     /mol_type="genomic DNA"
                     /strain="DSM 6725"
                     /type_material="type strain of Caldicellulosiruptor
                     bescii"
                     /db_xref="taxon:521460"
                     /note="type strain of Caldicelulosiruptor becscii DSM
                     6725"
     gene            1..2865
                     /locus_tag="ATHE_RS00855"
                     /old_locus_tag="Athe_0174"
                     /db_xref="GeneID:31771547"
     CDS             1..2865
                     /locus_tag="ATHE_RS00855"
                     /old_locus_tag="Athe_0174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014043207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="WP_041726955.1"
                     /db_xref="GeneID:31771547"
                     /translation="MIDLSGFLTILKRTKFVIVYLLVILLILLCKISAFASSEVPTLQ
                     DYLKKVGNVERPKKEIIIEAINYTSSSNASVRKISQFYGQKDVLLWEKEGGWLEWSVN
                     IPEDGFYNMALLYYPLPGKGLGIEFSVFIDGKIPYKEAQKVTFPRVWKDTTGIRKDKK
                     GNDLRPKCDEHQQWQKIDFIDTEGFYNKALPFYFTKGEHKIRLISIREPIALKQLIIY
                     NSEELPTYEEYISKSREKNSKNVFIKIQGENTYLKSDPILYPTYDRTDPATEPYHVSK
                     IRLNTIGQWNWRYPGMWISWIFEVPQDGYYKIAIKARQNFVRGLSVHRKLYIDGKIPF
                     KEAEDIEFPYSISWYMKTIGKKNQPYLIYLKKGVHELRLESTLGAFSEILSRVESTTI
                     DLNNLYRKIIMITGTSPDLYRDYFLEEQIPELVSTLKRLSNELEEEAAMFEKLAGQKG
                     GEAEFLRRVALQLRSMAEDTDTIPGRLTSFRDNLSGLSSWLAYRRDQPLEIDYILITS
                     PEEKLPSPTASIGNKIVNSIKAFLYSFVEDYNNVGEVYQGQKVIKVWVGGGRDQAQII
                     RDLINDSFTPQTGIKVNVSLVQAGLIEAILAGKGPDIVLTVSRAQPVNLAARGALVDL
                     SKFKDFNEVKKRFAKTALVPYTYNGGVYGLPVTQDFYMMFYRKDILKELNIELPRTWD
                     DMYKVIAKLQRYNLQVGLPYQRIDALEAIDAGLGARNLFPTLLLQFGGSFYDKTKTRT
                     LLDRPEAVAAFKTWTDFYTKYNLPLIYDFYNRFRTGEMPLGIAPYTTYNLLSTAAPEI
                     RNEWGMAPIPGVKKPNGEIDRSTGGSGTACIILKKSRNKEACWEFLKWWTSDEIQTQF
                     GKELEMLMGTAARYNTANLRAFQRLPWNKEEIENLETQWKYVKEIEEVPGSYYITRSI
                     DSAFSAVVYQGINPRESMWKYTKEINDELERKRIELSLNK"
     gene            2918..3811
                     /locus_tag="ATHE_RS00860"
                     /old_locus_tag="Athe_0175"
                     /db_xref="GeneID:31771548"
     CDS             2918..3811
                     /locus_tag="ATHE_RS00860"
                     /old_locus_tag="Athe_0175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013431286.1"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]; GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0008643 - carbohydrate transport [Evidence
                     IEA]; GO:0055085 - transmembrane transport [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="WP_013431286.1"
                     /db_xref="GeneID:31771548"
                     /translation="MSLIEDIKKNKASYLMIAPYMLLFTIFTLIPVISSIFLSFTNYN
                     MLQPPKWVGWSNYIRLFLNDKIFLKVLRNTLIFAFLTGPLSYFMSFFLAWFISEFNPK
                     LRAFLTLVFYSPSLAGNVFFIWSFIFSGDVYGLINGWAMKLGIIDEPINWLQDPNYIL
                     WVIIIVQLWLSMGAGFLAFVAGFQNLDRELFEAGAIDGIKNRFQELWYITIPQMAPQL
                     LFGAVMQIGASFGVSTVVMALGGLPTREYSADTVVTYLIDYGTVRFEMGYASAIAVVL
                     FIAMLLTNKVITSVLRRYSFD"
     gene            3866..4714
                     /locus_tag="ATHE_RS00865"
                     /old_locus_tag="Athe_0176"
                     /db_xref="GeneID:31771549"
     CDS             3866..4714
                     /locus_tag="ATHE_RS00865"
                     /old_locus_tag="Athe_0176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020615445.1"
                     /GO_process="GO:0008643 - carbohydrate transport [Evidence
                     IEA]; GO:0055085 - transmembrane transport [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="WP_041727298.1"
                     /db_xref="GeneID:31771549"
                     /translation="MLVWRKQNRSLGGNIVIFIILAVLGIFMALPLVYTIVNAFKPFD
                     EIFIFPPRLYVRRPTLDNFVLLFQLATNMWVPFSRYVFNSLFICIVGTVGHIFIASLA
                     AYPLAKHQFAAKRIINEIIVLALLFTPQVTYIPLYIIMSNLKLIDTYGALIFPAWQMT
                     LGLFLMRQFMTQIPDALLEAAKIDGANEFLTWWRIVMPNVKPAWLTLMILSFQQLWNQ
                     TGGSFIFSESLKPLPTLMSQIAAAGIARAGVGAAVALVLMIPPIVLFIISQSSVMETM
                     VNAGIK"
     gene            4744..6894
                     /locus_tag="ATHE_RS00870"
                     /old_locus_tag="Athe_0177"
                     /db_xref="GeneID:31771550"
     CDS             4744..6894
                     /locus_tag="ATHE_RS00870"
                     /old_locus_tag="Athe_0177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015906802.1"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YIP1 family protein"
                     /protein_id="WP_015906802.1"
                     /db_xref="GeneID:31771550"
                     /translation="MKVKVRTVKVELKSIKRSIVLIFAISLIFQIISTTKVYAYIIED
                     MREVPYYQYNYDVYQHEIPSAAGYYPAKTIRGEYIGSGSFKNPTDLYVDNNNTIYIMD
                     SGNKRVIVCDKDFKLKKIIDKFFDSNGTIQLIEPDGIFVDKSGLIYICDKGSKLVWIF
                     NQDGKLIRTIEKPVSDLKAAKKDFIPFKVVVDNAGIIYVLSLGSFEGAYMFDQNGNFL
                     GFYGSNKVVVTWQLLVDRFWKSILTKEQKSSMVRYLPTECTSIDIAKDGFIYTCSNYT
                     DVSEGEIRKLNYLGENILWYKKQGRTRDYGDISKYQGKELEDSYFIDIDVTDDGFINA
                     LDYERGRIFQYDQNANLLFICGGKGDQVGTFKDPVAIDSIANDLVVLDKLKGTITVFK
                     ETKLGSLVHKATLLYNEGKYDDARHLWEQVHKMDFNFSLAHVGLGKALLRMDKYSDAM
                     YYFRLANDKDGYSEAKEVLRNEFLKRNFGVIATTVIAIIVLLYVLIKRFRKPPTAQDI
                     YTKKIDKYKYPLHVMLHPFRGFEELKEERKGSVIIATFIVFIFFVTMVINRQYTGFIF
                     NPYRQDKINILSIFSSTVGIFFFWVLSNWMVSTLTEGEGKFGEIWVFSAYSLTPYIIC
                     TLLAVVMSQFMIAEEAMFINFVRLIGTLWLVICIFNAIKSVHQYTPSKTIGTIALSVL
                     GVGIILFIIVLMLTLFGQLIDFINNVYSEILLRI"
     gene            6922..9123
                     /locus_tag="ATHE_RS00875"
                     /old_locus_tag="Athe_0178"
                     /db_xref="GeneID:31771551"
     CDS             6922..9123
                     /locus_tag="ATHE_RS00875"
                     /old_locus_tag="Athe_0178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013431283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5696 domain-containing protein"
                     /protein_id="WP_015906803.1"
                     /db_xref="GeneID:31771551"
                     /translation="MFDLKKYKLIRTIGIIFAIIITQILSFQKIYADSEISFQKIAAN
                     DRLELYVNKKYGYFKVLDKKTNIVWLSNPENWKEDTVAAGSMKTQLASQLVVKYAFME
                     SYAIQTSNSYVSSAMKRGLKIKPIKNGYIATYSFKKEGFVIPVAVTISNDYLNIEVLV
                     NQIKELKKEKYRLVSIMLLPFFGAASKSDKGYIVVPDGCGAVINFNNKKGEEEYSQRV
                     YGPDYALIREPNTYVTQYARLPVFGMNKNDSGFLAVVTNGDSKAIINAYTSGVRTNFN
                     QVFSEFIIREQDSVTFREKQWNEKTFNIFEENIPNQTKYSIRYYFLDKNKSDYIAMAE
                     KYREYLIKEKGLKKEDQQKLPLYIELYGGMKKTKYIVGLPRNVTIPLTTFDDAIEISK
                     RLKNIGIKDIVVKYTGWYENGVYYNLPISPKPEKVLGGWKGFRKMIDYFNRNNIKAYF
                     DVDFVTFRKGSLFYPLNVVATKSLRKMPAKLIRYSPATCYADDDYPLLFMVSPSYVTK
                     FVDKFIGSKHAEIKNISISTISKMLYSDFGSKQINRLKTEEIFTNLVEKVTKQYNVLL
                     TSPNGYLIPKGKEIIDVPISSSKFAIEDYEIPFYQMVLRGYIPYSTPAINDYTNDWMV
                     LLKTLETGSFLKFTWTARNEDELKETMCDFLYSSNYRMWLNDVKSMYRKIYPVLQQIN
                     NKKFLEHKVLKEGLVYVKFDGGVEILLNYTSSDQKVGNTVVKARDFKVIKR"
     gene            9131..10051
                     /locus_tag="ATHE_RS00880"
                     /old_locus_tag="Athe_0179"
                     /db_xref="GeneID:31771552"
     CDS             9131..10051
                     /locus_tag="ATHE_RS00880"
                     /old_locus_tag="Athe_0179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015906804.1"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]; GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0008643 - carbohydrate transport [Evidence
                     IEA]; GO:0055085 - transmembrane transport [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="WP_015906804.1"
                     /db_xref="GeneID:31771552"
                     /translation="MQRTNLLKIFPKRKLTLRQKEALYGRLFILPWLIGLVIFFIIPF
                     INSIYYTFHKIRLGDNGLEFEFIGWENYIYAFTKDPDYLKNLTSSITNMLYEVPIVII
                     FSVFVAYLLKDDFKGRTFARTIFFFPVIIASGVVITVLKENVLGSNTSSMVASSTTIF
                     KAENLRAVMINAGVPRWFSMYIVDIVNKIFDLTWRSGVQILLILAALHNIPKSFYEVA
                     IIEGATEWEKFWKITFPMISPTILVAVIYSIIDYFTDYGNQVMRMVVNQANNGKFEYS
                     TTLAITYFLVVMIIILIVNRIIGKRVVYLT"
     gene            10081..11100
                     /locus_tag="ATHE_RS00885"
                     /old_locus_tag="Athe_0180"
                     /db_xref="GeneID:31771553"
     CDS             10081..11100
                     /locus_tag="ATHE_RS00885"
                     /old_locus_tag="Athe_0180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015906805.1"
                     /GO_process="GO:0008643 - carbohydrate transport [Evidence
                     IEA]; GO:0055085 - transmembrane transport [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="WP_015906805.1"
                     /db_xref="GeneID:31771553"
                     /translation="MKVARAIKLNYTFEKFRITDVSKLVFKKNLFIVLKKLFLYTFII
                     CMSYILLYPILFLISNALRAKEDLFDPSVIWIPKHITFKNFEYANMLLSYPLAIKNTL
                     IILIPSVIIQTFICMMVGYGFARFRFAERELLFGILLFTIIVPMQTIIVPLYMKFRYF
                     DFLYIGKLIGIFTGKPMTINLLDTPWPFYILNFFGMGIRSSLYIFVFRQFFRNMPVEL
                     EEAAKIDGCGPFSTFLRIMVPNATGAIITILLFTIVWHWNDYYVSAMFCNENLPVSVM
                     LTALNNRMSMIQDAYGFSSDDIYLIGSNVLEAGCLMVILPLIIVYIIGQRYFTESIER
                     TGIVG"
     gene            11175..12962
                     /locus_tag="ATHE_RS00890"
                     /old_locus_tag="Athe_0181"
                     /db_xref="GeneID:31771554"
     CDS             11175..12962
                     /locus_tag="ATHE_RS00890"
                     /old_locus_tag="Athe_0181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013431280.1"
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]; GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="WP_013431280.1"
                     /db_xref="GeneID:31771554"
                     /translation="MVRPKIVKRIISVLVAICMLASVALIVGKSPQRVQASSKLGDIS
                     FLRPGFSKESLKSTDIFNKAVAKAIEDYQKKYGGKVNIVYSDWNNWQTKIIARMAAGD
                     PIDVIFGGTGTFPAFYNRGLVQPLDKYVDLKAPYINKRAMDYAFKYNGHYYLASQKGS
                     NVPWLVIYNKDLMLEEGIDEEEMPLALYKKGRWNWDTFAALAKKLTADTNKDGKIDRY
                     GVNFWAATAIVYANGTQFVKVDSSGKGKVNFDNPALQRALNFYKKGAKEGWLARDWDI
                     TVSGLKKRQTVMLVAPQYKFDQDKREVEDELEAAPLPLGPDNKSGLYPFDADGYGIMK
                     GSKNPVGAGKFINLLLESVQKNHDDVNAKNRPKYLVDFVNKLAEKSFYPGLGESMLGM
                     PHWDIFGRVDSSDSVAAALSSLRPQVEKNVKEASAGAINAVYKPFKPFTINFEDGKLD
                     TFKVLDTSKKTVKLSIASGKEAIKGKSLKVTWDQGKDGGEIYVVTAPEKVKIYGWHDY
                     TVSFDVKVLKAPKAGKTTVVCSILNDTKPNATSYGSITKTIDKGQTVYHVEGNITNIP
                     DNSDKMCLRIGVQEGVDFVIDNIKVVELE"
     gene            13068..17084
                     /locus_tag="ATHE_RS00895"
                     /old_locus_tag="Athe_0182"
                     /db_xref="GeneID:31771555"
     CDS             13068..17084
                     /locus_tag="ATHE_RS00895"
                     /old_locus_tag="Athe_0182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015906806.1"
                     /GO_function="GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 43 glycosylhydrolase"
                     /protein_id="WP_015906806.1"
                     /db_xref="GeneID:31771555"
                     /translation="MKILRMFKNLIIETIILSMILWLFFSHNASFISAVGGEALRGGT
                     AATNPIILADIPDPDIVRVGKDYYMVSTTMHMTPGVPIMHSTDLVNWRIIGYVYDRLE
                     ENDAHNLKNGQNVYGKGQWAPCIRYHKGKFYVIFASLDSGKTYLFSSAKITGPWERVE
                     FHEYLHDPTLLFDDDGKVYIIYGNKEIRIRELTPDLKAFNPLGLNKVIIKSKIEGLEE
                     GSHAYKINGRYYITTIRWEKGKIREECIYRSDRIDGPYEGKVVLSDTMGYKNNGVAQG
                     GLIDTPDGKWFSMLFQDHDAVGRVPVLVPVRWKNGWPVFGDENGKVPIRFVKPGRSSF
                     ETEIVKSDEFYQEKIETNFRRFEVERNLEITAQEELAVNGDFKRGKVGWKGKDGSKVE
                     VVKEENRNVLHVYSISDQGTGVQQNFTGKIMKGKKYKSVFRVKYTKGAETVEFVLCAR
                     LSNGNNVISKELVKGLAQKNEWTTISSIFEIDQNFDTISLLVKVLSIGNKQEKVTEFY
                     VDFFSVKEVLFTSKEPEQVAPNGSVLNLTWQWNHNPDNTKWSLLERKGFLRLRTCDVV
                     NDIQQARNTLTQRTIGPKCSGWILMDVSKMNDGDVAGLAAFQKEYGFIGVSKQRNKYY
                     IIMVDKGKEVARENLQQMMVYLKIDFDFEVDKAYFYYSYDGINWTKCGSELEMKYTLP
                     QHFMGYRFAIFNFATKKPGGYVDIDFFKFENKLTGIKTENYLKAYFDKTEILLDNSTD
                     KKYQVSICVNSLPKNEKIEQVELLLNHPEWIDVAGIKKENKLLENAIVKVIKREANQT
                     TISISNIKKELIDKDNKWQRIVNIQLKQKIKLSESNKGEISIKSFVLQTEKEKISYGS
                     DAAVTKVEYTAPKVPIGKIPPNANPLISHKFGADPAVLVYNDRVYVYLTNDILEYDAD
                     GNIVDNTYSKINKITVISSEDLVNWTDHGEIEVAGPNGVAKWATQSWAPSIAYKKING
                     KDKFFLYFANNASGIGVLTSDSPIGPWVDPLGRPLISRSTPGVEGVVWLFDPAVLVDD
                     DGKAYIYFGGGVPQGQDQMPNTARVMQLGDDMISVVGSAKTIHAPFMFEDSGINKING
                     IYCYSYCTNFYGGSRPQGSPPAGVIAYMISKNPMGPWEYRGVILNNPGYFFGVGGNNH
                     HQIFMFKGKWYITYHAQTLAKDMGAAKGYRSPHINEVVIEGDKIREVVADYKGVNQVK
                     LFDPYRLVEAETFAWCAGVSTKKADASNNMCLTDINDGDWIALSKVDFGNAGAKKFEA
                     IVNNVNGESLIEIKLDSLDGRTIAVVEVKHQQEFLSKWTKVETKVEKVTGVHDLYFVF
                     RGKKQNKLFDMDYWRFMK"
     gene            17101..19194
                     /locus_tag="ATHE_RS00900"
                     /old_locus_tag="Athe_0183"
                     /db_xref="GeneID:31771556"
     CDS             17101..19194
                     /locus_tag="ATHE_RS00900"
                     /old_locus_tag="Athe_0183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013431278.1"
                     /GO_function="GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endo-1,4-beta-xylanase"
                     /protein_id="WP_015906807.1"
                     /db_xref="GeneID:31771556"
                     /translation="MKKRKFKILYLFLIIVLSVSFIISIVFPSFFKAAQTTSTNINFE
                     GRDKLTFFAYGKAKITIDQNIAQEGKKSIKVTDRKSVWDSFGIDVKDVLQRGKTWVVS
                     AYVKHKGKKPIEFSITAIYNDGRGLKYLQLGEKIVIPNKWDKIVAKWKPTLKNPMDLI
                     IAIHPTVDKTTAYNVDNIQIMTEEVYQSQAVVFKDTFESNLTNWQPRGDTVKLKIDNT
                     KSHNGNKSLYVSGRSAFWHGVQIPVTKYLVAGKVYKFSVWLYHQSIDKQGFGLTIQRK
                     MANDEQYKYDWITGSQIEGDGWVEISGNYYVPKDGKIEELVFCVSSWNPTLAFWVDDV
                     TISDPFKLQGPNYNLPSLKEKYKEDFKVGVAIGYGELISDIDTQFIKKHFNSITPGNE
                     MKPESVLKGPNNYDFTIADAFVDFATKNKMGIRGHTLVWHNQTPDWFFKDENGNFLKK
                     DELLKRLKNHIYTVVSRYKGKIYAWDVVNEAIDETQPDGYRRSNWYNICGPEYIEKAF
                     IWAHEADPQAKLFYNDYNTEIPQKRMFIYNMIKNLKAKGVPIHGIGLQCHINIDNPSV
                     EDIEETIKLFSTIPGLEIQITELDMSFYQWGSSVYYAEPSREMLLKQAKKYYELFNLF
                     KKYKNVIKSVTFWGLKDDNSWLRGVFNKPDFPLLFDEHYDGKPAFWALIDYSILPQNA
                     NLPTPPAIPKVKAKK"
     gene            19237..20742
                     /locus_tag="ATHE_RS00905"
                     /old_locus_tag="Athe_0184"
                     /db_xref="GeneID:31771557"
     CDS             19237..20742
                     /locus_tag="ATHE_RS00905"
                     /old_locus_tag="Athe_0184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013431277.1"
                     /GO_function="GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH39 family glycosyl hydrolase"
                     /protein_id="WP_015906808.1"
                     /db_xref="GeneID:31771557"
                     /translation="MTYVKIERGKIFGVFPDNWKFCVGSGRIGLALQKEYMEALEYVK
                     KHIDFKYLRAHGLLHDDVGIYREDSVGDMKQPFYNFTYIDKIYDSFLELGIRPFVEIG
                     FMPSKLASGTQTVFYWRGNVTPPSDYGKWEKLIKAVVKHFIDRYGEKEVENWPFEIWN
                     EPNLNVFWKDADQNEYFKLYEVTAKAIKDVNENIKVGGPAICGGADHWIDDFLNFCYK
                     NNVSVDFVTRHAYTAKPPTYTPHFVYHDLHPIDYMLNEFKMVREQVKNSPFPNLPIHI
                     TEYNSSYHPLCPVHDTPFNAAYLARILSEGGDYVDSFSYWTFSDVFEEADVPRSLFHG
                     GFGLVAFNNIPKPVFHMFTFFNAMGRDILYRDDHILVTKRADGSVAIVAWNEVISKEQ
                     EIEREYKLEIPIDFEDIFVKQKLIDEEHANPWRVWIEMGRPRYPSKEQIKTLKEIAKP
                     YVSTCRMRAREGYVTLNIKLGKNAVVLYELNKVNDETHTYIGLDDSKIPGY"
     gene            20762..21775
                     /locus_tag="ATHE_RS00910"
                     /old_locus_tag="Athe_0185"
                     /db_xref="GeneID:31771558"
     CDS             20762..21775
                     /locus_tag="ATHE_RS00910"
                     /old_locus_tag="Athe_0185"
                     /EC_number="3.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015906809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endo-1,4-beta-xylanase"
                     /protein_id="WP_015906809.1"
                     /db_xref="GeneID:31771558"
                     /translation="MSEDYYEKSTVSLTEKYKEFFKIGAAVTVKDFEGIHGRILTKHF
                     NSLTPENDMKFERIHPKEDFYNFEATDKIKDFALKHNMQLRGHTLVWHNQTPEWVFRD
                     NDKEAPKELVIERLREHIKTICTRYRDVVYSWDVVNEAVEDKTDVLLRDSKWRRIIGD
                     DYIKIAFEIAKKYTGNGKLFYNDYNNEMPYKLEKTYKVLKSLLEEGTPIDGVGIQAHW
                     NIWDKNLIDNLKRAIETYASLGLEIQITELDISVFEFEDRRTDLLEPTEEMVELQAKV
                     YEDVFRVFREYRDVITSVTLWGISDRHTWKDNFPVIGRKDWPLLFDIDGKPKKAFFRI
                     IDF"
     gene            21823..22620
                     /locus_tag="ATHE_RS00915"
                     /old_locus_tag="Athe_0186"
                     /db_xref="GeneID:31771559"
     CDS             21823..22620
                     /locus_tag="ATHE_RS00915"
                     /old_locus_tag="Athe_0186"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015906810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_015906810.1"
                     /db_xref="GeneID:31771559"
                     /translation="MAIMEINFYSKRLKRSTTLMAVLPVDRFDRSFSKKSDVDSLKVL
                     YLLHGYAGNHMDWLYGAQIVELSLKYNVAIFMPCGENSFYLDDEDREAYYSEYIGNEL
                     IEFTRNVFPIPEDREKTFIGGLSMGGYGALRNGLKYHKIFGGIIALSSALIIHKIAGI
                     TPDFKDGIASYKYYRHVFGDLSSLIGSDKDINALAKKLKKEGVDIPKIYMACGKDDFL
                     VHENRELYNFLKKEELNVTYEEDEGTHDWQFWNRYIFKAFEWVEKVF"
     gene            22710..23876
                     /locus_tag="ATHE_RS00920"
                     /old_locus_tag="Athe_0187"
                     /db_xref="GeneID:31771560"
     CDS             22710..23876
                     /locus_tag="ATHE_RS00920"
                     /old_locus_tag="Athe_0187"
                     /inference="COORDINATES: protein motif:HMM:NF013400.5"
                     /GO_function="GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH39 family glycosyl hydrolase"
                     /protein_id="WP_015906811.1"
                     /db_xref="GeneID:31771560"
                     /translation="MKINIYPEIKLGKINKFWTKCVGSCHAATALREDWRKQLKKCRQ
                     ELGFKYVRFHGWLNDDMSVCFRNDEGKLWFSFFNIDSIIDFLLDIGMKPFIELSFMPE
                     ALASGTKTVFHYKGNITPPKSYEEWGQLVKELTRHLVKRYGKNEVREWFFEVWNEPNL
                     KDFFWAGTMEEYFELYKHAAFAIKIVDSELKVGGPASAVDAWILELKEYCQKNGVPID
                     FITTHQYPTDLAFSTSSNMEEAMAKAKRGELAERVKKALSEAEPLPLYYTEWNNSPSP
                     RDPYHDIPYDAAFIVKTIIDIIDLPLGCYSYWTFTDIFEECGLSSLPFHGGFGLLNIH
                     GIPKPSYRAFQILNKLDGEKVELKVEEKSPTVDCIAAINGNELVLVISNHNVPP"
ORIGIN      
        1 atgatagatt tgtctgggtt tttaacaatt ctgaaaagga caaaatttgt cattgtatat
       61 ttactagtca tattactcat attgctctgt aaaatctcag catttgcttc aagtgaagta
      121 cctacccttc aagattacct aaaaaaagtg ggaaatgttg aaagaccaaa gaaagaaatt
      181 ataattgagg caattaatta cacaagttca agtaatgcaa gtgtcagaaa aatatcacaa
      241 ttctatgggc aaaaagatgt gcttttatgg gaaaaagaag gtggatggtt agagtggagt
      301 gtaaatattc cggaagatgg attttataat atggctcttc tctattatcc tttgccaggt
      361 aaagggctgg ggatagaatt tagcgtattt attgatggaa aaattcctta taaagaagcc
      421 caaaaagtta catttccaag agtatggaag gatacaacag gaattaggaa agataaaaaa
      481 ggcaatgatt tgagaccaaa atgtgatgaa caccagcaat ggcaaaaaat tgattttata
      541 gatactgagg gtttctataa caaagcttta ccgttctatt ttacaaaagg cgaacataaa
      601 attagactta taagtattag agagcctatc gcattgaagc agttgattat atataacagt
      661 gaggaattac caacttatga ggagtacata tcaaaaagtc gtgaaaaaaa ttcaaaaaat
      721 gtgtttataa aaattcaagg tgagaataca tatctaaaat ctgatccaat actatatcct
      781 acttatgata gaaccgaccc cgcaacagag ccttatcatg tttctaaaat aagacttaac
      841 acaataggtc agtggaattg gcgttatccg gggatgtgga taagctggat ttttgaagtt
      901 ccgcaggatg gatattataa aattgcaata aaagcaagac agaattttgt ccgagggtta
      961 tctgttcaca gaaagttata tattgacgga aaaattcctt tcaaagaagc tgaggatatt
     1021 gaatttccat atagtattag ctggtatatg aaaacaatag gcaagaaaaa tcaaccatat
     1081 ctaatatatt tgaaaaaagg tgttcatgaa ttaaggttgg aatcaaccct gggtgctttt
     1141 tcagagattt tgagtagagt tgaaagtacc acaatagatt taaacaattt gtatagaaaa
     1201 ataataatga ttacaggcac atcacctgac ttgtatcgtg actatttcct tgaagagcaa
     1261 ataccagagc ttgtcagtac attaaaaaga ttaagcaatg agctggaaga agaagctgct
     1321 atgtttgaaa aacttgcagg gcaaaaaggc ggagaagctg agtttttaag aagagttgct
     1381 cttcaactca ggagtatggc tgaagatact gacacaatac ctggaagatt aacaagtttt
     1441 agagacaatt tgagtggatt atcttcgtgg cttgcatata gaagagatca gccattagag
     1501 atagattata ttttgattac atctcctgag gaaaagctgc cctcgccgac agcttctatt
     1561 ggtaataaga ttgttaattc aataaaagca tttttgtatt cctttgttga agattacaat
     1621 aacgtaggtg aagtgtatca ggggcaaaag gttattaaag tttgggttgg cggtggtcgc
     1681 gatcaggcgc agattataag agatctaatc aatgattcat ttacaccaca gacaggaatt
     1741 aaagtaaatg ttagcctggt tcaagcagga ttaattgaag caatacttgc aggaaaaggt
     1801 ccagatatag ttttaacagt ttcaagggca caaccagtta atttagccgc acgtggtgca
     1861 cttgttgatt tgagcaaatt taaagatttt aatgaagtta aaaaaaggtt tgctaaaact
     1921 gctttagttc catatacgta taatggcggt gtatatgggc ttccagttac tcaggatttt
     1981 tatatgatgt tttacagaaa agatatctta aaagagctaa atattgaatt gccacgaaca
     2041 tgggatgata tgtacaaagt catagcaaag cttcagagat ataatcttca ggttggtctt
     2101 ccatatcaaa ggattgacgc tcttgaagca attgatgcgg ggcttggtgc aagaaatctc
     2161 tttcctacat tattgcttca gtttggtgga agcttttatg acaaaacaaa aacacgaaca
     2221 ctattggata gaccagaagc tgtagctgca tttaagactt ggacagattt ttacacaaag
     2281 tacaatcttc ctttgatata tgacttttac aacagattca gaacaggtga gatgccactt
     2341 ggaatagcac catataccac gtataacctg ttatcgacag ctgcacctga aattcgaaat
     2401 gaatggggaa tggcaccaat acctggggta aaaaagccaa acggtgaaat agaccgttct
     2461 acaggtgggt caggtacagc atgtataata ttaaagaaaa gcagaaataa agaagcatgc
     2521 tgggagtttt tgaaatggtg gacatctgat gaaattcaaa cacagtttgg gaaagagctt
     2581 gagatgctga tgggtactgc tgcaagatac aatacagcaa atttgagagc ttttcaaaga
     2641 cttccatgga acaaagagga gatagaaaat ttagagacac agtggaaata tgtaaaagaa
     2701 atagaggaag ttccaggaag ttattacatt acaagaagta tagacagtgc attttcagct
     2761 gttgtttatc aggggataaa tccaagagaa agtatgtgga aatatacaaa agaaatcaac
     2821 gatgagcttg aaagaaagag gatagagctt agtttgaata aataattgaa aaatatttaa
     2881 aaagattttc ataattccat gaagggagat tttatagatg agcctaattg aagacataaa
     2941 aaagaataaa gcaagttatt taatgatagc tccatatatg ttattattta cgatattcac
     3001 attaattcca gttataagct ctatattttt aagttttaca aattacaata tgcttcagcc
     3061 acctaaatgg gttggatggt caaattatat aagattgttt ctaaatgata aaatattttt
     3121 aaaggtgctc aggaatactc taatatttgc atttttgaca ggaccgctta gctattttat
     3181 gtcttttttc cttgcatggt ttataagtga gttcaatccg aagttgagag catttttaac
     3241 acttgtattt tattcacctt cacttgctgg aaatgtgttt ttcatatggt cgtttatatt
     3301 cagtggcgat gtttatggac ttataaatgg atgggcgatg aaacttggga ttatagatga
     3361 gcctattaac tggcttcagg acccaaatta cattttatgg gtaattataa tagttcagct
     3421 ttggcttagt atgggtgctg gatttttggc atttgttgca ggttttcaga atcttgatag
     3481 agaactattt gaagcaggag caattgacgg cataaaaaac agatttcaag aactttggta
     3541 catcacaatc ccgcagatgg caccacagct tttgtttggg gctgtaatgc aaataggtgc
     3601 atcatttggt gttagcacag ttgttatggc acttggggga ctgccaacaa gggagtacag
     3661 tgcagacact gttgtgactt atcttattga ctatgggaca gtcagatttg aaatgggcta
     3721 tgcttcagca attgcagttg tgctttttat tgctatgctt ttgactaaca aggttattac
     3781 gtcagttttg agaagatatt catttgatta gtatatgtat tctaaattta caaagagtag
     3841 gtgagtttag ttgaacagaa aagcaatgtt ggtgtggaga aaacaaaaca gaagccttgg
     3901 agggaatata gtaatattca ttatcttagc ggtactgggt atatttatgg cattaccgct
     3961 tgtttatacg atagtcaacg catttaagcc atttgatgaa atctttattt tccccccacg
     4021 gctatatgta cggcgtccta cacttgataa ctttgtctta ctgtttcaac ttgcaacaaa
     4081 catgtgggtg cctttttcaa gatatgtttt caacagctta tttatatgca ttgttggcac
     4141 agttggtcat attttcattg catcgcttgc tgcttatccg cttgccaagc atcaatttgc
     4201 ggcaaagagg attataaatg agataatagt tcttgcactg ctttttacac cgcaggttac
     4261 atatattcct ctttatataa ttatgtctaa cttaaagctt attgatactt atggagcact
     4321 gatttttccg gcttggcaaa tgactctggg gctatttcta atgagacagt tcatgaccca
     4381 gattccagat gcacttttag aagctgctaa aattgatggt gcaaatgaat ttttgacatg
     4441 gtggcgtata gttatgccaa atgttaagcc tgcgtggctg acgcttatga ttttatcatt
     4501 tcagcagctc tggaaccaga caggtggttc gttcatattc agtgaaagtt taaagccact
     4561 gcctactctt atgtcacaaa tagcagcagc gggtattgct cgtgctggag ttggtgctgc
     4621 tgttgcgctt gtgctaatga ttccacctat tgtacttttt atcatatcgc aaagcagcgt
     4681 catggaaaca atggtaaatg caggtattaa atagtaaata gttatgttgt aatttcttaa
     4741 actatgaaag taaaggtgag gacagtgaaa gttgaattaa aaagtataaa gagaagtata
     4801 gtactcattt ttgccataag cctaatattc caaataataa gtactacaaa agtgtacgca
     4861 tatataattg aagatatgcg tgaagttcca tattatcaat acaattatga tgtatatcag
     4921 catgaaatac caagcgctgc tggttattat ccagcaaaaa ccataagagg agaatatatc
     4981 ggttcaggca gttttaaaaa tccaacagat ctatatgttg ataacaataa tactatctat
     5041 attatggaca gtggcaacaa gcgagtaata gtctgcgata aagacttcaa acttaagaaa
     5101 attatagata aatttttcga ttctaatgga actattcaac ttattgaacc agatggaata
     5161 tttgtcgata aaagtggttt aatttacata tgtgataagg gttctaaact ggtctggata
     5221 ttcaaccaag atggcaaatt aataagaacc atagaaaagc ctgtatcaga cctgaaagct
     5281 gctaaaaaag attttattcc atttaaagtt gttgttgata atgcagggat tatctatgtt
     5341 ctttctttgg gaagttttga aggtgcttat atgtttgacc aaaatgggaa ttttttgggg
     5401 ttttacggga gcaacaaagt agttgttaca tggcagttat tggttgatag gttttggaag
     5461 agtattttaa caaaagaaca gaaaagttct atggtaagat atttaccaac ggaatgtacc
     5521 agcatcgaca tagctaaaga tggatttata tatacctgtt caaattacac tgatgtaagc
     5581 gaaggtgaaa taagaaaatt aaactattta ggcgaaaaca tactttggta taaaaagcaa
     5641 ggcagaacaa gagactatgg tgatatttca aaatatcagg ggaaggagtt ggaagattca
     5701 tattttatag atattgacgt gactgatgat ggatttatca atgcacttga ttatgaacga
     5761 ggacgaattt ttcagtatga tcaaaatgcg aatttgctat tcatatgtgg agggaaaggt
     5821 gatcaggtag gcacatttaa agatccagtg gctatagata gtatagcaaa tgatttagtt
     5881 gttcttgata agctaaaagg aacaatcaca gtttttaaag aaacaaaatt aggaagctta
     5941 gtacataaag caacgctgct atataatgaa ggtaagtacg atgatgcaag gcatttatgg
     6001 gaacaagttc acaaaatgga tttcaatttt tcacttgcac atgtaggtct tggcaaagca
     6061 cttttgagga tggataaata ttcagatgcg atgtattatt tcaggcttgc aaatgataaa
     6121 gatggttatt cagaggcaaa agaagtttta agaaatgaat ttttaaaaag aaattttggg
     6181 gttatagcaa caactgtaat tgctataata gtacttttgt atgtattaat aaaacgcttt
     6241 agaaagccac ctacagctca agacatttat actaaaaaga tcgacaagta taaatatcct
     6301 ttacatgtaa tgctgcatcc atttagaggc tttgaagaat taaaagaaga gaggaaaggt
     6361 tctgttataa ttgcaacatt tattgtgttt atattctttg taactatggt cataaataga
     6421 caatacacag gatttatctt taatccgtat agacaagata aaattaacat attgtcaata
     6481 ttctcaagta cagttggtat atttttcttc tgggtacttt ctaactggat ggtatccact
     6541 cttactgagg gtgaaggcaa gtttggagaa atatgggtat tttcggcata ttctctgaca
     6601 ccatatatta tttgtactct tttagcagtt gttatgagtc aattcatgat tgcagaagaa
     6661 gcaatgttta taaactttgt aagacttatt ggcaccttat ggcttgtaat atgcatattt
     6721 aatgcaataa aatctgttca tcagtatact ccaagtaaaa ctataggcac aatagctttg
     6781 agtgttttgg gagtaggaat aattcttttc attattgtat taatgcttac actgtttgga
     6841 cagttaatag actttatcaa taatgtgtac agcgagatac tcctcaggat atagctaacc
     6901 ttttaaaagg aggcatataa attgtttgat ttaaaaaagt ataaactaat cagaacaatt
     6961 ggaataatat ttgcaataat cattacacaa atattaagtt ttcaaaagat ttatgcagac
     7021 tctgaaataa gttttcagaa gattgctgcc aatgataggt tagaattgta tgtgaataaa
     7081 aaatatggtt atttcaaagt tttagacaag aaaacaaata ttgtatggtt gagcaatcca
     7141 gaaaattgga aagaagacac tgttgcagca ggaagtatga aaacacagct tgcatctcaa
     7201 cttgtagtaa aatatgcttt tatggagtca tatgcaattc aaacgtcaaa cagctatgta
     7261 agctctgcaa tgaaaagagg tttgaaaata aagccaataa aaaatggata tatagccacg
     7321 tattcattca aaaaagaggg ttttgtaata cctgttgcag taacaatttc gaacgactat
     7381 ctgaatattg aagtgttagt caatcaaatt aaagaactta aaaaagaaaa ataccggctt
     7441 gtttccatta tgctcttgcc gttttttgga gcggcaagta aaagcgataa gggttatatt
     7501 gttgtaccag acggttgtgg agctgtgata aatttcaaca ataaaaaagg agaagaagag
     7561 tattcacagc gagtatatgg tcctgattat gccttaatta gagagcccaa cacgtatgtt
     7621 acgcagtatg caaggttacc tgtctttgga atgaataaga atgattcggg gtttttggcg
     7681 gttgtaacga atggagattc aaaagcaata ataaatgcct atactagtgg cgttagaaca
     7741 aattttaatc aagttttcag cgaatttatc ataagagaac aagacagtgt cacatttaga
     7801 gaaaagcagt ggaatgaaaa aacgtttaat atatttgaag agaacattcc aaatcaaaca
     7861 aagtactcta ttagatatta tttccttgac aagaataaat cagactatat tgcgatggct
     7921 gaaaagtata gagaatatct aataaaggag aaaggtctta aaaaagaaga ccagcagaaa
     7981 ttacctttat atattgaatt atacggtgga atgaagaaaa caaaatatat tgttgggcta
     8041 ccaagaaatg taacaatacc attaactaca tttgatgatg ctattgaaat ttcaaagaga
     8101 ttgaaaaata taggtattaa agacatagtt gtgaagtata caggatggta tgaaaatgga
     8161 gtgtattata atcttcccat ttcaccaaaa cccgagaaag ttctgggtgg gtggaaaggg
     8221 tttagaaaaa tgatagatta cttcaataga aataatataa aagcatattt tgatgtagat
     8281 tttgtaacat ttagaaaagg ttcattgttt tatcctctga atgttgttgc cacaaagtct
     8341 ttgagaaaaa tgccagcaaa acttattaga tattcaccag ctacatgcta tgcagatgat
     8401 gattatcctc tactatttat ggtatctcct tcatacgtga ccaagtttgt tgacaaattt
     8461 attggatcca aacatgcaga gataaaaaat atatctatct caacaatttc taaaatgtta
     8521 tattcagact ttggttcaaa acaaataaac aggttaaaaa cagaagagat ttttactaat
     8581 ttggtagaga aggtgacaaa gcagtataat gttttattaa caagtccaaa cggctattta
     8641 atacctaagg gaaaagaaat aattgatgta cctatttcaa gcagcaaatt tgcaattgag
     8701 gactatgaaa taccatttta tcagatggtg ctaagaggat atattcctta ttctacacca
     8761 gcaataaacg attatactaa tgattggatg gtgttattga aaacattgga aacaggatca
     8821 ttcttaaagt ttacatggac cgcgagaaat gaggatgaat tgaaggaaac aatgtgtgat
     8881 tttctctact catcaaatta taggatgtgg ttaaatgacg taaagagtat gtacagaaaa
     8941 atttatcctg tactgcaaca aataaataat aaaaaattct tagagcacaa ggtattaaag
     9001 gagggacttg tgtatgttaa gtttgatggt ggagtggaga tattgttaaa ttatacttca
     9061 tctgaccaaa aggttggaaa tactgttgta aaagcaagag attttaaagt tattaagagg
     9121 tgaatattta atgcaaagaa ctaatttatt aaaaatattt ccaaaaagaa agcttactct
     9181 taggcaaaaa gaagcgttat acggcagatt atttatcctg ccatggctaa ttggacttgt
     9241 tatattcttt ataattcctt ttataaattc catatattac acgtttcaca aaataagatt
     9301 aggcgacaat ggtttggagt ttgaatttat tggatgggaa aattatatat atgcgtttac
     9361 aaaggacccc gactatttaa aaaatttgac atcgtctata acaaatatgc tgtatgaagt
     9421 tcctatagta ataattttca gtgtttttgt tgcatatttg ttaaaagatg atttcaaggg
     9481 aagaaccttt gccagaacca tatttttctt tccggtaatt atagcatcag gagttgttat
     9541 aacggtattg aaagaaaacg tccttggaag caacacatca agcatggtgg cttcatctac
     9601 aacaattttt aaggctgaga atttgagagc ggttatgata aacgcaggtg taccaagatg
     9661 gttcagtatg tatattgtcg acatagtaaa taagatattt gacctgacat ggaggtctgg
     9721 ggttcagata cttttgatac ttgcagcgct acacaacatt ccaaaaagtt tttatgaagt
     9781 tgcaataatt gaaggtgcga cagaatggga gaagttttgg aagataactt ttccaatgat
     9841 ttcgcccaca atacttgttg cagtcatata ttcaataatt gattatttta ctgactatgg
     9901 caaccaagta atgagaatgg ttgtaaatca ggcgaataac gggaagtttg aatatagtac
     9961 aactttagca ataacctatt tcttagtggt tatgataata attttaattg taaacagaat
    10021 aattggtaaa agggttgttt acttaactta aatttgattt atgaagagag gcgagattaa
    10081 atgaaagttg caagagcaat taagctcaac tatacctttg aaaagtttag aattacagat
    10141 gtttcaaagc tagtattcaa aaaaaatcta tttatagttt taaagaagct atttctgtac
    10201 acattcataa tatgcatgag ctacatacta ttgtatccaa tactatttct aataagtaat
    10261 gcactaaggg caaaagagga tttgtttgac ccgagcgtta tatggatacc gaagcatata
    10321 acttttaaaa actttgaata tgccaatatg cttttatcat acccattggc aataaaaaat
    10381 acgttaatta tcctaattcc atcggttatt attcagacat tcatatgcat gatggtcggg
    10441 tatggttttg ctaggtttag atttgcagaa agagagttat tattcgggat attgcttttt
    10501 acaattattg ttccaatgca aacaataata gtcccacttt atatgaaatt tagatatttt
    10561 gattttcttt acattggcaa acttatagga atttttactg gaaaaccaat gacaataaat
    10621 ttgcttgata caccttggcc attttatata ctgaattttt tcgggatggg aataaggtca
    10681 agtttgtaca tctttgtttt caggcaattc tttagaaata tgccagttga attggaggaa
    10741 gcagcaaaga ttgacggatg cggaccattt tcaacatttt tgagaataat ggttcctaac
    10801 gcgacaggag caataataac aattttgctc tttacaatag tatggcactg gaacgactat
    10861 tatgtttcgg ctatgttctg taatgagaat ttgcctgtat cagtaatgtt aaccgcactc
    10921 aacaacagga tgagcatgat tcaggatgca tatggttttt catcagatga tatttacctg
    10981 attggttcta atgtacttga agcagggtgt ttgatggtaa ttttaccact gattattgtg
    11041 tatatcattg gacagagata ttttactgaa agtattgaac gtacaggtat agttggttaa
    11101 aaaattgggc tttaatcccc ataaaaacag taggggatta aaaataaaaa acatgaatga
    11161 ggaggtttga gattatggta agaccaaaga ttgttaaaag aattatttcg gttttagtag
    11221 ctatttgtat gcttgcttca gttgctttga ttgtgggcaa gtctccacaa agagtgcaag
    11281 cgtcatcaaa acttggtgac atttcattct taagacctgg tttttctaaa gagagtttaa
    11341 aaagtactga cattttcaac aaagcagttg caaaggcaat tgaagactat cagaaaaaat
    11401 atggtggaaa agtaaacata gtatattctg actggaacaa ctggcaaaca aagataattg
    11461 caaggatggc tgcaggtgat ccaatcgatg ttatttttgg aggaaccggg acatttccgg
    11521 cattttacaa cagagggctt gtacaaccac ttgataagta tgttgatttg aaagctccat
    11581 atataaacaa aagagcaatg gactatgcat tcaagtacaa tggtcactac tatttagcaa
    11641 gccagaaagg ttcgaatgtt ccatggctgg ttatatataa caaagactta atgttagaag
    11701 aaggtattga tgaagaagaa atgccgcttg ctctttacaa gaagggaaga tggaactggg
    11761 atacatttgc cgcacttgct aagaagctga cagctgatac aaataaagat ggaaagattg
    11821 ataggtatgg tgtaaacttc tgggcagcaa cagctattgt atacgcaaac ggcacacagt
    11881 ttgttaaggt tgattcatct ggtaaaggca aggtaaactt tgataatcca gcgcttcaga
    11941 gagcattgaa cttctacaaa aagggtgcaa aagaaggctg gcttgctaga gactgggata
    12001 taacagtttc tggtttgaag aagagacaaa ctgtaatgct tgttgcacca caatataaat
    12061 ttgatcagga caagagagag gttgaagatg agcttgaagc tgctccattg ccacttggac
    12121 cagacaacaa gtcagggctt tatccattcg atgcagacgg gtatggcatt atgaagggtt
    12181 caaagaatcc agttggtgct ggaaagttta ttaacctgtt attagaaagc gtccaaaaga
    12241 atcatgatga tgtcaatgca aaaaatagac caaaatactt agtagatttt gttaataagc
    12301 ttgcagaaaa atctttctat ccaggcttag gagagtcaat gcttggtatg ccacactggg
    12361 atatattcgg aagagttgac agttctgact ctgttgcagc tgcattgtca agtttgagac
    12421 ctcaagttga aaagaacgtc aaagaagctt cagctggtgc tattaatgca gtttacaaac
    12481 cattcaagcc atttacaatt aactttgagg atggaaaatt agatacattc aaagttttag
    12541 atacatcaaa gaagacagtt aaactttcaa ttgcttcagg taaagaagct ataaaaggaa
    12601 aatccttgaa ggtaacttgg gaccaaggaa aagacggtgg cgagatttat gtagtaacag
    12661 caccagaaaa ggttaagata tacgggtggc atgactatac tgtaagcttt gatgtcaaag
    12721 tcttgaaagc accaaaagct ggcaagacga cagttgtatg ttcaatcctc aatgatacaa
    12781 aaccaaatgc aacatcttat ggcagcatta caaagacaat tgataaaggt cagactgtct
    12841 accatgtaga aggtaatatt acaaatattc cagataactc tgacaagatg tgcttgagaa
    12901 ttggcgttca agaaggagta gactttgtaa ttgataatat taaggttgta gaacttgaat
    12961 aattataaaa tgtgacactt attacagggc atactcataa aataagagta tgccctgtaa
    13021 taacaaatat ttctagtgta tttaaagtag tgaaggtagt gaatcatatg aagattttga
    13081 ggatgtttaa aaatttaatt atagaaacaa tcattttgag tatgatacta tggttgtttt
    13141 ttagtcataa cgcaagcttt atttctgccg taggaggaga agcattgaga gggggaacag
    13201 ctgcaacaaa tccgataatt cttgctgata ttcctgatcc tgacattgtt agagttggaa
    13261 aagactatta catggtcagc accacaatgc atatgacacc aggtgttcca attatgcatt
    13321 caacagatct tgtgaactgg aggataattg gctatgttta tgacaggtta gaagaaaatg
    13381 atgcacataa tttaaaaaat ggtcaaaacg tttacggaaa agggcaatgg gcaccttgta
    13441 taagatacca taaaggtaaa ttttatgtaa tatttgcttc attagattct ggcaagactt
    13501 acttgtttag ctcagcgaaa attacgggac catgggagag ggtggaattt cacgaatatc
    13561 tccatgatcc aaccctttta tttgatgatg atgggaaagt ctacattata tacggtaata
    13621 aagaaataag aattagagaa ttaactccag atttaaaagc ttttaatcca ctgggactga
    13681 acaaggtaat tattaaatct aaaattgaag gacttgagga aggttcacat gcttacaaaa
    13741 taaacggtag gtactacata acaacaattc ggtgggaaaa aggaaaaata agagaagaat
    13801 gtatatacag atcagataga attgatgggc catatgaagg gaaagttgta ctcagtgata
    13861 ccatgggata caagaataac ggtgttgcac agggaggact tatcgataca ccggatggaa
    13921 aatggttttc aatgcttttt caagaccatg acgcagttgg gcgtgttcca gttcttgtgc
    13981 ctgtcaggtg gaaaaatgga tggccagtct ttggagatga aaatggtaaa gttccgataa
    14041 gatttgtaaa gccgggcagg agcagttttg aaactgaaat tgtgaaaagc gatgagtttt
    14101 accaagaaaa aatagaaaca aatttcagaa gatttgaagt tgagagaaat ttggaaatta
    14161 cagcacaaga agagcttgca gtaaacggcg attttaaaag ggggaaagtt ggctggaaag
    14221 gcaaagatgg ttcaaaggtg gaagttgtga aagaagaaaa cagaaatgtt cttcatgtct
    14281 attctatttc agaccaaggt acaggagtgc aacaaaactt tactggtaaa attatgaaag
    14341 gaaaaaaata taaatctgtt tttagagtta aatacacaaa aggtgctgaa actgtagaat
    14401 ttgtcttatg tgcaagactg tcaaatggaa ataatgtgat ttccaaagag cttgtaaagg
    14461 gattggcgca aaaaaatgaa tggacaacaa tatctagtat atttgagatt gaccagaatt
    14521 ttgatacaat atcattatta gtaaaagttt tatctattgg aaataaacag gagaaagtaa
    14581 ccgaatttta tgtggacttt ttctctgtaa aagaggtgct ttttacaagt aaagaaccag
    14641 aacaagtagc accaaatggt tcggtattaa acttgacgtg gcaatggaat cataaccctg
    14701 ataacacaaa gtggtctttg cttgaaagaa aaggctttct tagattaaga acttgtgatg
    14761 tggtaaatga tatacagcag gcaagaaata cgttgactca gcgaactata ggtccaaaat
    14821 gttcaggatg gatacttatg gatgtaagta agatgaatga tggggatgtt gctggacttg
    14881 ctgcatttca aaaagagtat gggtttatcg gtgtttcaaa gcagagaaac aaatattata
    14941 taataatggt tgataaaggg aaagaagttg caagagaaaa tttacagcaa atgatggtgt
    15001 atttaaagat tgattttgat tttgaagttg ataaagcata tttctactac agctatgatg
    15061 gaattaattg gacgaaatgt ggttctgaac ttgaaatgaa gtataccttg ccccagcatt
    15121 ttatgggata cagatttgca atattcaatt ttgcgacaaa aaagccaggc ggttatgttg
    15181 atatagattt ctttaaattt gagaataaac taactggcat aaaaacagaa aattatttga
    15241 aggcatattt tgataaaact gaaattttac ttgataactc tactgataaa aaatatcaag
    15301 tttctatttg cgtaaattct cttcctaaga atgaaaaaat agaacaagtt gaacttttgt
    15361 tgaaccatcc tgaatggatt gatgttgctg gcataaaaaa agaaaataag ctgcttgaaa
    15421 atgcaattgt aaaagtaatt aaaagagaag caaatcagac aacaatttca atttctaaca
    15481 taaaaaaaga gcttatagac aaagataata aatggcagag aatagtaaat attcaactaa
    15541 aacaaaaaat aaaactatca gagtcaaata aaggtgaaat atcaattaaa tcatttgttt
    15601 tacaaacaga gaaagaaaaa attagttatg ggagtgacgc tgcagtgaca aaggtagaat
    15661 acactgcacc taaagtacca ataggtaaaa ttccacctaa tgcaaatcct ctaatttcac
    15721 acaagtttgg tgctgacccc gctgttcttg tttacaatga tagggtatat gtttatctta
    15781 caaacgacat tttagagtat gacgcagacg gaaatattgt ggacaatacc tatagtaaga
    15841 taaataaaat tactgttatt tcttctgaag accttgtcaa ttggacagac catggagaga
    15901 ttgaagttgc aggaccaaat ggagttgcaa aatgggcaac tcagtcatgg gctccaagca
    15961 ttgcttacaa aaaaataaat ggcaaagata aattcttcct gtactttgca aataacgcaa
    16021 gcggtatagg tgttttgaca agcgacagtc caataggtcc atgggtggat cctcttggaa
    16081 gaccattaat ttcaaggtct acaccgggag tagaaggcgt tgtttggcta tttgaccctg
    16141 cagtcttggt agatgatgat ggaaaggcat acatttactt tggcggtgga gttccgcaag
    16201 gacaagacca aatgccaaat actgcacgtg ttatgcaact gggtgatgat atgataagtg
    16261 ttgtaggaag tgcaaaaacc attcatgcac catttatgtt tgaagattct ggtattaaca
    16321 agataaatgg aatttactgt tattcctact gcacaaactt ttatggtgga tcaagaccac
    16381 agggaagtcc acctgctggt gtaatagctt acatgattag taaaaatcct atggggccat
    16441 gggaatacag aggagttata ctcaacaatc ctggatattt ctttggagtt ggtggcaata
    16501 atcatcacca gatttttatg tttaaaggta aatggtatat tacatatcat gcgcaaactc
    16561 ttgcaaaaga tatgggtgca gctaaaggat acaggtcacc gcatataaac gaggttgtta
    16621 ttgagggtga taagatcaga gaggttgttg cggattataa aggtgtcaat caagtaaagc
    16681 tgtttgatcc gtatagactg gttgaagctg agacatttgc atggtgtgca ggtgtgtcca
    16741 caaagaaagc agatgcaagt aacaacatgt gtcttactga tattaatgat ggtgattgga
    16801 tagctctttc aaaagtagat tttgggaatg ctggagcaaa aaagtttgaa gcgattgtga
    16861 ataatgtaaa tggtgaaagc ttaatagaga taaagcttga ttctttagat gggagaacca
    16921 ttgcagttgt ggaagtcaaa catcagcaag aatttttatc caagtggaca aaggtagaaa
    16981 caaaggttga aaaagtaaca ggagtgcatg atttgtattt tgttttcaga ggtaaaaaac
    17041 aaaataaatt gtttgatatg gactattgga gatttatgaa atgaaaggag taactgggag
    17101 atgaaaaaaa ggaaattcaa aatattatat ttatttttaa ttatagtact ttctgtatca
    17161 tttattatat caatagtttt tccatcattt tttaaggcgg cacagacaac ctcaacaaac
    17221 ataaactttg aaggaagaga caagttaaca ttttttgcat atggcaaagc aaaaataaca
    17281 atagaccaaa acatagcaca agaaggaaaa aagagtataa aagttacaga caggaaaagt
    17341 gtatgggata gctttgggat agatgtaaaa gatgttttac aaagaggaaa aacatgggtg
    17401 gtatcagcct atgtaaaaca taaggggaag aagccgatag aattttcaat aacagctatt
    17461 tataatgacg gcagggggtt aaagtacctt cagcttggtg agaaaattgt cataccaaac
    17521 aaatgggaca aaattgttgc taagtggaaa ccaacgttaa aaaacccgat ggacttgatt
    17581 attgcaattc atccaacagt tgataaaaca actgcatata atgtggacaa tattcaaata
    17641 atgacagaag aagtttatca atcacaagct gttgttttta aagatacatt tgaatcaaat
    17701 ttgacaaact ggcagccaag aggtgatact gtaaaactaa aaatagataa tacaaaatcg
    17761 cataatggaa ataagagtct ttatgtatca ggtcgttcgg cattctggca tggagttcaa
    17821 attcctgtga caaaatatct tgttgctggg aaggtataca aatttagcgt atggctgtat
    17881 catcaatcaa ttgacaagca aggttttggt cttaccattc aaagaaagat ggcaaacgat
    17941 gaacaatata aatatgattg gataactgga agccagattg aaggtgatgg ctgggttgag
    18001 ataagtggta attattatgt accaaaggat ggcaaaatag aagaacttgt attttgtgtt
    18061 tcttcgtgga acccaacatt agcattttgg gtagatgatg ttacaatatc tgatccgttt
    18121 aagttacagg gacctaatta taatttgccg tctttaaaag agaaatataa agaagatttt
    18181 aaagttggtg tagctattgg atatggtgaa cttattagtg atatagacac acaatttatc
    18241 aaaaaacatt ttaacagtat aacaccaggc aacgagatga aacccgaaag tgtgctaaaa
    18301 ggaccaaaca actatgactt tacaatagcg gatgcatttg tggattttgc aacaaaaaat
    18361 aaaatgggta tacgcggaca tactcttgtc tggcacaacc agacacctga ttggttcttc
    18421 aaagatgaga atggcaattt tttaaagaag gatgaacttt tgaaaaggtt aaaaaatcat
    18481 atatacacag ttgttagccg gtataaaggc aaaatatatg cttgggatgt tgtcaatgaa
    18541 gctattgatg aaacacaacc tgatggttac agaaggtcaa actggtacaa tatttgtgga
    18601 cccgaatata tagaaaaagc gtttatttgg gcacatgagg cagatccaca agcaaagtta
    18661 ttttacaatg attacaatac cgaaattcca caaaagagaa tgtttatata taacatgatt
    18721 aaaaatttga aagcaaaagg tgttccaata catggtatag gtcttcaatg tcacataaat
    18781 attgacaatc cttctgttga agatatagag gagacgataa aactatttag cacaattcca
    18841 gggcttgaga ttcaaattac tgagcttgac atgagctttt atcaatgggg ttcttctgtt
    18901 tattacgcag agccatcaag agaaatgtta ttaaaacagg caaagaaata ctatgagtta
    18961 tttaacctat ttaagaagta caaaaatgtc ataaaaagcg ttacattctg ggggcttaag
    19021 gatgacaact cttggctgag aggagttttt aacaaaccag attttccgct tttatttgat
    19081 gagcattatg atggcaaacc tgctttctgg gcgttgatag actattcaat attaccacaa
    19141 aatgccaatt tgcctacacc acctgctatt ccaaaagtaa aggctaaaaa ataatatttt
    19201 atcgtttaac attacatgat attgggggaa tagataatga catatgtaaa aattgaacga
    19261 ggaaaaatat ttggtgtatt tccagataat tggaaatttt gtgttggtag cggtcgtata
    19321 gggcttgcgc ttcaaaagga gtatatggaa gcattagaat atgtaaaaaa gcatattgat
    19381 tttaaatatt taagagctca tggtttgctt catgacgatg ttggaatcta ccgcgaagat
    19441 agtgttgggg atatgaagca gccgttttac aattttactt atattgataa gatatatgat
    19501 tcatttttgg agcttggaat acggcctttt gttgagatag gatttatgcc gtcaaaactt
    19561 gcatctggaa cacaaacagt attttactgg aggggtaatg ttacccctcc cagtgattat
    19621 ggaaagtggg agaagctaat taaagcagtt gttaaacact tcatagacag atatggcgaa
    19681 aaagaggttg aaaactggcc gtttgaaata tggaacgaac caaatttaaa tgtattttgg
    19741 aaagatgctg atcaaaatga atattttaag ctatatgaag tgacagcaaa ggctataaaa
    19801 gatgtaaatg agaatataaa ggttggtggg cctgcaatat gtggcggggc agaccactgg
    19861 atagacgatt ttttgaattt ttgttataaa aataatgttt ctgttgattt tgttacacga
    19921 catgcgtata cagcaaaacc ccctacttat acaccacatt ttgtttatca cgatttacat
    19981 ccaattgatt acatgttaaa cgaatttaaa atggtacgag agcaggtaaa aaattcaccg
    20041 tttccaaatt tgccgataca tattactgaa tacaacagtt cataccatcc gctttgccct
    20101 gttcacgaca cgccgtttaa tgcggcatac cttgcaagga tattaagcga aggaggagat
    20161 tatgtagatt cgttttctta ttggacattc agtgatgtat ttgaagaagc agatgtacca
    20221 aggtctctgt ttcatggtgg gtttggcctt gtagctttca ataatattcc aaaacctgtg
    20281 tttcacatgt ttacattttt caatgcaatg ggaagagata ttttgtatag agatgaccat
    20341 atcttggtaa caaaaagagc agatggttca gttgcgattg tggcatggaa tgaagttata
    20401 agtaaagaac aagagattga aagagaatac aagctggaaa ttcctattga ctttgaggat
    20461 atttttgtaa agcaaaaatt aattgacgaa gaacatgcaa atccatggcg tgtatggatt
    20521 gagatgggaa gaccaaggta tccgtcaaag gaacagataa aaactttgaa ggaaattgca
    20581 aaaccgtatg ttagcacttg cagaatgaga gcaagagagg gttatgtaac acttaatatc
    20641 aagttaggta agaatgcagt tgtgctttat gagctcaata aagttaatga cgagacgcat
    20701 acatatatag ggcttgatga tagtaaaatt ccaggttatt gaaaaaggag gatattgtat
    20761 aatgagcgaa gattattatg aaaagtctac tgtatcactt acggaaaaat ataaagagtt
    20821 ctttaaaatt ggtgcagctg ttacagtgaa agattttgaa ggaatacacg gaagaattct
    20881 tacaaagcat tttaacagtt taacacctga gaatgatatg aaatttgaaa gaattcatcc
    20941 gaaagaagat ttttacaact ttgaagctac tgataagatt aaagattttg cacttaaaca
    21001 taatatgcaa ctgagaggac atacacttgt atggcacaac caaacacctg aatgggtttt
    21061 tcgtgacaat gacaaagaag caccaaaaga gcttgtaata gaaagactga gggaacacat
    21121 aaagacaatt tgcacaagat accgcgatgt ggtttattcg tgggatgttg tgaatgaagc
    21181 tgttgaggat aaaacagatg ttctgctcag agattcaaag tggagaagaa tcataggtga
    21241 tgattatatt aagattgcct ttgaaatagc taaaaagtat acaggaaatg ggaaactatt
    21301 ttataacgac tataacaatg aaatgccata caagttagaa aagacataca aggtcttaaa
    21361 aagtctttta gaagaaggaa ctccgattga tggtgttggc atacaagcac actggaatat
    21421 ttgggataag aatttaatag acaaccttaa gagagctatt gaaacatatg catccttggg
    21481 gcttgaaata caaataacag agcttgatat atcagtattt gaatttgaag acagaagaac
    21541 tgacctatta gagcccactg aagagatggt ggagttgcaa gctaaggttt atgaggatgt
    21601 gtttagagta tttagggagt atagagatgt tataacgtca gttacattat gggggattag
    21661 cgatagacat acatggaaag acaattttcc ggtaataggc agaaaagact ggccattgct
    21721 gtttgacatt gatggaaagc caaaaaaggc atttttcaga ataattgact tttgaattaa
    21781 tgaacttaaa aaaaataatg ctcaaaaagg agatagattt aaatggctat aatggaaata
    21841 aatttttatt caaagaggct caaacgaagc acaaccctca tggcagtttt gccagttgat
    21901 aggtttgata ggagtttttc gaaaaaaagt gatgttgaca gtttgaaagt actttatttg
    21961 ttgcatggat atgcgggcaa tcacatggat tggttgtatg gagctcagat tgtagaattg
    22021 tctttaaaat ataatgtagc gatatttatg ccttgtggag aaaatagttt ctatttggat
    22081 gatgaggata gggaagcata ctatagtgag tatataggaa atgaacttat cgagtttaca
    22141 agaaatgtat ttccaatacc tgaagataga gaaaaaacgt ttattggtgg actttctatg
    22201 ggtggctacg gcgcgttgag aaatggctta aaatatcaca agatatttgg tgggataatt
    22261 gcgctttcct cagctttaat aatccataaa atagctggaa taacaccaga ttttaaggat
    22321 ggtattgcaa gctacaaata ttacagacat gtatttggcg acctgtcctc tttgattggc
    22381 agtgacaaag atataaatgc tcttgccaaa aagctgaaaa aagagggtgt agacattccc
    22441 aaaatttata tggcatgtgg caaagatgat ttccttgttc atgagaacag agaattgtac
    22501 aatttcctaa aaaaagaaga gctaaatgta acgtatgaag aagatgaagg tactcatgat
    22561 tggcagttct ggaacaggta tatttttaag gcttttgaat gggtagaaaa agtcttttaa
    22621 aatagctttt ttaggggaag agagattttt acgcctcctc tctttccttt ttttaaaaaa
    22681 tttagtatat gaaaggagag caaacacaca tgaaaataaa tatttatcca gaaattaagt
    22741 taggcaagat aaataaattc tggacaaagt gtgtaggcag ctgtcatgca gcaactgccc
    22801 tgagggagga ttggagaaag cagctgaaaa agtgtaggca agaacttggg tttaaatatg
    22861 tcagatttca tggctggctt aacgatgata tgagtgtttg cttcagaaat gatgagggca
    22921 aactttggtt ttcatttttc aacattgatt ctattattga ctttttattg gatattggaa
    22981 tgaaaccttt tatagaattg agctttatgc ctgaagcttt agcatctggt acaaagacag
    23041 tttttcatta taagggcaat ataactccgc caaaatccta tgaagagtgg ggacaacttg
    23101 ttaaagaact tacaagacat cttgtaaaaa gatatggtaa aaatgaggta agagagtggt
    23161 tttttgaggt atggaacgaa ccgaatttga aggacttttt ctgggcaggg acaatggagg
    23221 agtattttga gctttataag catgcagcgt ttgcaatcaa gatagttgac tctgaactga
    23281 aagtaggagg acctgcatca gcagtagatg cgtggatttt ggagctgaaa gagtattgtc
    23341 agaaaaatgg agtaccaata gattttataa caacacacca gtatccaaca gatttagcgt
    23401 ttagcacaag ttctaatatg gaagaagcca tggcaaaagc aaaaagaggt gagcttgctg
    23461 aaagagtaaa aaaggctttg agtgaagcag aacctttgcc tttgtattat actgagtgga
    23521 ataactcgcc gagtccgcga gacccgtacc acgatattcc atatgatgca gcatttattg
    23581 tgaagactat aatagacatt attgatttgc cgcttggttg ttactcatac tggacattca
    23641 cagatatatt tgaagagtgt gggctaagtt cattgccttt ccatggaggg tttggacttt
    23701 taaatattca cggtatacca aagccgtcat atagagcatt tcaaatattg aataaattag
    23761 atggagaaaa ggtagaactt aaagttgaag aaaaaagtcc aactgtagac tgcatagcag
    23821 ctataaatgg caatgaatta gttcttgtta tttcaaacca taatgttccg ccttag
//
