LOCUS       NC_009004               7570 bp    DNA     linear   CON 17-SEP-2024
DEFINITION  Lactococcus cremoris subsp. cremoris MG1363, complete sequence.
ACCESSION   NC_009004 REGION: 1815995..1823564
VERSION     NC_009004.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMEA3138204
            Assembly: GCF_000009425.1
KEYWORDS    RefSeq; complete genome.
SOURCE      Lactococcus cremoris subsp. cremoris MG1363
  ORGANISM  Lactococcus cremoris subsp. cremoris MG1363
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Lactococcus.
REFERENCE   1  (bases 1 to 7570)
  AUTHORS   Wegmann,U., O'Connell-Motherway,M., Zomer,A., Buist,G.,
            Shearman,C., Canchaya,C., Ventura,M., Goesmann,A., Gasson,M.J.,
            Kuipers,O.P., van Sinderen,D. and Kok,J.
  TITLE     Complete genome sequence of the prototype lactic acid bacterium
            Lactococcus lactis subsp. cremoris MG1363
  JOURNAL   J Bacteriol 189 (8), 3256-3270 (2007)
   PUBMED   17307855
REFERENCE   2  (bases 1 to 7570)
  AUTHORS   Wegmann,U. and Linke,B.
  CONSRTM   MG1363 Sequencing Consortium: Institute of Food Research (Norwich,
            United Kingdom), Groningen Biomolecular Sciences & Biotechnology
            Institute (Groningen, The Netherlands), Alimentary Pharmabiotic
            Centre and Department of Microbiology (Cork, Ireland)
  TITLE     Direct Submission
  JOURNAL   Submitted (27-SEP-2006) Wegmann, U., Institute of Food Research,
            Food Safety Science Division Norwich Research Park, Colney, Norwich
            NR4 7UA, England Linke, B., Center for Biotechnology, Bielefeld
            University Universitaetsstrasse 25, 33615 Bielefeld, GERMANY
COMMENT     REFSEQ INFORMATION: The reference sequence is identical to
            AM406671.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000009425.1-RS_2024_09_17
            Annotation Date                   :: 09/17/2024 02:43:27
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,590
            CDSs (total)                      :: 2,504
            Genes (coding)                    :: 2,386
            CDSs (with protein)               :: 2,386
            Genes (RNA)                       :: 86
            rRNAs                             :: 7, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 64
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 55 of 118
            Pseudo Genes (incomplete)         :: 43 of 118
            Pseudo Genes (internal stop)      :: 33 of 118
            Pseudo Genes (multiple problems)  :: 12 of 118
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..7570
                     /organism="Lactococcus cremoris subsp. cremoris MG1363"
                     /mol_type="genomic DNA"
                     /strain="MG1363"
                     /sub_species="cremoris"
                     /db_xref="taxon:416870"
     gene            complement(1..990)
                     /locus_tag="LLMG_RS09190"
                     /old_locus_tag="llmg_1835"
     CDS             complement(1..990)
                     /locus_tag="LLMG_RS09190"
                     /old_locus_tag="llmg_1835"
                     /function="Transcriptional regulators"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011835605.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA];
                     GO:0003700 - DNA-binding transcription factor activity
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="WP_011835605.1"
                     /translation="MTKITLKEIATMADVSVMTVSNVIRGKDSRVSAETKAKIQALVK
                     KYNYVPNQNAANLRSGKSKLIGVLFYNKSQNIDFTDPFISSVLTGIERRAKEEGYFTM
                     VHTVQNAKGIEQLQRNWAFAGFIVVGVSNKDFLQIDQAILTPVSYIDTYFEDTKKLDD
                     KLRNFIGTNEEKISESIANHLTEMGHEEVLFYSFDFNQEEPSVIEKRYHAFHKFFKGE
                     ILFATTKSADYQEILKSVSVYLMEQPFTAIYATADILAAKLNQIFKEISIVGVDDAEF
                     DEFISPKLTTVAINQVEKGNVAMGSLINSIEKEISENYSSESLLIIRDSVKKL"
     gene            complement(1077..3296)
                     /locus_tag="LLMG_RS09195"
                     /old_locus_tag="llmg_1836"
     CDS             complement(1077..3296)
                     /locus_tag="LLMG_RS09195"
                     /old_locus_tag="llmg_1836"
                     /function="Alpha-glucosidases, family 31 of glycosyl
                     hydrolases"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011835606.1"
                     /GO_function="GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIM-barrel domain-containing protein"
                     /protein_id="WP_011835606.1"
                     /translation="MVSELESKYMNNNIIKFDKARFTVLTEHLIRIEYSETGEFEERM
                     TQMVQNREFSEVNFDIIEKEETIEIITSTVHLYYNGGEFTNASLFADVKFNFSVYSNR
                     WYFGEKSDGNLKGTTRTLDMIDGECPLEDGIMSKNGFAVLADKGKVLTEVGDIAGNSV
                     STIDLYLFAYGRDYRQALKDFYQLTGNTPKLPRFALGNWWSRYYDYSDKSYLALMDKF
                     TDKKVPLSVSVIDMDWHKVSEVPSRFGSGWTGYSWNKKLFPNPENFIDELHQRKLKVT
                     LNDHPADGIRAFEDPYPQVAQTLDLNTELEEAAKFDFDNLKFRKAYFEEVHGPLEKEG
                     VDFWWIDWQQGAISKSGVDPLWLLNHYQYQNAQKKHKNNIILSRYAGPGSHRYPLGFS
                     GDSVISWASLDFQPYFTSTASNIGYTWWSHDIGGHMQGYKDAELSLRWLQFGVFSPIN
                     RLHSSKSEFTSKEPWHFDAVIEQSMIDFLQLRHQLIPYLYSANLITASEGRALVEPLY
                     YEYPMEEEAYQHRNQYLFGEQLMVAPITEKMNSLLQMGSVEVWFPEGTWYDFFSGQPY
                     DGKVSLKVYREITEMPVFAKAGAIIPLDKNPLKKEEIPSEIIWKIFPGADGEYLLLEE
                     DNETKAEFVNGIFTVTSKKESSRKHTIIYGEHEIVSAKRGEFSIDLNGKEENFDWNFS
                     TALFRRLDIAEISYEQKDEILQQLSLIEEHEKQVAFIKTNENQELQNSLFELLYSGK"
     gene            complement(3323..3964)
                     /locus_tag="LLMG_RS09200"
                     /old_locus_tag="llmg_1837"
     CDS             complement(3323..3964)
                     /locus_tag="LLMG_RS09200"
                     /old_locus_tag="llmg_1837"
                     /function="Predicted integral membrane protein"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011835607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="WP_011835607.1"
                     /translation="MNKMGKLLNIDSSVMRIMALFADLIILNTLFILTSLPVITIGAS
                     FCALQTSLQKILHQKRGSVVKNYFKSFKINFKQATIFFTTLSLLTFILFCDFRLVGHL
                     PLLLSFLMRTAAFIGTLILALLIVYGFSYIGRYKNSLKKTVYNILLISIQNWFQSLFL
                     LIFNGFIIYFSFTSPYALLTMIYFLTFGGFSVINLVNSIMIKQVFDRIERVTH"
     gene            complement(4042..5604)
                     /locus_tag="LLMG_RS09205"
                     /old_locus_tag="llmg_1838"
     CDS             complement(4042..5604)
                     /locus_tag="LLMG_RS09205"
                     /old_locus_tag="llmg_1838"
                     /function="ABC-type sugar transport system, periplasmic
                     component"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011675691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="WP_011835608.1"
                     /translation="MKNQKMVVAAGAASMLAALALLSACGNSSSSKEGNSSNKDFTVA
                     TVRWADWGNDYTKFPNQLAKEAGINVKWDTYLNADWGDKKSTLMAGGNLPDTFMGSIT
                     FTDQEIAQNQSNFIPLEKYVKDIPNLQKAMKKNPALKAMITSPDGHIWSLPKEAPMRP
                     IIANQLFINKAWLDKLGLQMPTTYDEFVKVLEAFKTKDPNGNGKADEIPYGTGNFDPT
                     MSYTLPFGVLRGADNSNEMMMLNGKPAYIRSTDNFKKGIEAMNDAYTKGLIDPELYTL
                     DPTQAQAKLMADTETVGVSVGWTADATFGKNAKDYVALPALKGPDGNQYVMSDPDHFN
                     QGRDEFMVTTHAKNVKALIKWADKFYTNDAAIQNYYGAFGVGTEKSGEAYKVLKPTGN
                     NSADTQAWINSLRDFGPKSWDNSLNDKVTFEDPNNGDAQKLKMDAELKQYARPAFPSV
                     TYTNDELQKIAQVYPDLSSYTTQETAKWVTKGGIDKDWEAYIAKLNQMGLKDYLKIQT
                     DAYERYQKALKK"
     gene            complement(5667..>6407)
                     /locus_tag="LLMG_RS09210"
                     /old_locus_tag="llmg_1839"
                     /pseudo
     CDS             complement(5667..>6407)
                     /locus_tag="LLMG_RS09210"
                     /old_locus_tag="llmg_1839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014572955.1"
                     /GO_process="GO:0008643 - carbohydrate transport [Evidence
                     IEA]; GO:0055085 - transmembrane transport [Evidence IEA]"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
     gene            complement(6459..7570)
                     /locus_tag="LLMG_RS09215"
                     /old_locus_tag="llmg_1840"
     CDS             complement(join(6459..7354,7354..7570))
                     /locus_tag="LLMG_RS09215"
                     /old_locus_tag="llmg_1840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086896442.1"
                     /ribosomal_slippage
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence
                     IEA]"
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element IS981 family transposase"
                     /protein_id="WP_102032797.1"
                     /translation="MKKRYSKEFKETLVAFYHSGQSVTQLSKEYDVAPATIYKWIDLY
                     SKSNESSISKADFLELKRQLAKVKEERDNLKKSIDHIRREKEVSAADMAQTIQTLALN
                     VRLSCQLLDVPESSYYERINRHPSKTQLRRQYLSLKISQLFNANRGIYGAPKIHHLLL
                     KQGEKVGLKLVQKLMKQLQLKSVVIKKFKPGYSLSDHINRKNLIQTEPTKKNKVWSTD
                     ITYIPTQQGWAYLSTIMDRYTKKVIAWDLGKRMTVELVQRTLNKAIKSQDYPEAVILH
                     SDQGSQYTSLEYEELLKYYGMTHSFSRRGYPYHNASLESWHGHLKREWVYQFKYKNFE
                     EAYQSIFWYIEAFYNSKRIHQSLGYLTPNQFEKVSA"
ORIGIN      
        1 tcagagtttt tttacgctat cccgaatgat taggaggctt tccgaagagt aattttcaga
       61 aatttctttc tcaattgaat taatcaaact tcccattgcc acatttccct tttcaacttg
      121 gttaatggct actgttgtca atttaggcga gataaattca tcaaattctg catcatcaac
      181 tcctactatc gaaatctctt taaaaatttg atttaacttt gctgccaaaa tatcagcagt
      241 agcataaatt gccgtaaaag gctgctccat caaataaact gacacactct tcaaaatttc
      301 ctggtagtct gcgctttttg tcgttgcaaa caaaatttcg cccttaaaaa atttatgaaa
      361 agcatgataa cgtttttcaa taacacttgg ttcttcttga ttaaagtcaa aactataaaa
      421 tagaacttct tcatgcccca tttctgtgag atgattagca atactttctg aaattttttc
      481 ctcattggtg ccaataaaat ttcttaactt atcatctaat ttttttgtat cttcaaaata
      541 ggtatctata taactgactg gagttaatat cgcttgatca atttgcaaaa agtctttatt
      601 tgataccccg accacaataa aaccagcgaa agcccagttt ctttgaagct gctcaattcc
      661 ctttgcattt tggacggtat gaaccattgt aaaataaccc tcctccttcg ctcttcgctc
      721 aattccagtt aaaactgaag aaataaaagg gtcggtaaaa tctatgtttt gagatttatt
      781 ataaaataag acaccgatta atttcgattt tcctgaacgt aaattggctg cattttggtt
      841 gggaacataa ttatactttt tcactaaagc ttgaatttta gcttttgtct cagccgaaac
      901 gcgtgaatct ttcccacgga taacattaga gaccgtcatc actgatacat cagccattgt
      961 cgcaatttct tttaaagtga tttttgtcat agtcttcgtt tctaacaaga ggaagcattc
     1021 acctatatgt ttaagttttc agaacctctg tcatcctatt atacaaagct tcctctttat
     1081 tttccactgt aaagtaattc aaatagacta ttttgtaatt cttgattttc atttgttttg
     1141 ataaaggcca cttgtttttc atgttcttca atcaaagaga gctgctgtaa aatttcatct
     1201 ttttgctcat aagaaatttc tgcaatatct aatcttctaa acaaagcagt agaaaaattc
     1261 caatcgaaat tttcttcttt tccatttaaa tcaatagaaa attctcctct tttagcagat
     1321 acaatttcat gttccccgta aataatcgta tgtttgcgag aactttcttt tttacttgta
     1381 actgtaaaaa ttccattgac aaattctgct ttagtttcgt tgtcttcttc taataaaaga
     1441 tactcaccat cggctccagg aaatattttc cagattatct cactaggaat ttcttctttt
     1501 tttagaggat ttttatctag tggaataata gctcctgctt tagcgaaaac aggcatttct
     1561 gttatttctc gataaacttt caggctgacc ttcccatcat aaggttgacc gctaaaaaaa
     1621 tcataccaag ttccttctgg aaaccaaacc tccacacttc ccatctgtaa aagagaattc
     1681 attttttcgg taatcggtgc taccatcagt tgttcaccaa aaagatattg atttcgatgc
     1741 tgataagctt cttcttccat cggatattca tagtagagtg gttcaacaag tgctctacct
     1801 tcagaagctg ttattaaatt ggcgctataa agatatggaa ttaattgatg acgaagttgt
     1861 aaaaagtcaa tcattgattg ttcaatcacc gcatcaaaat gccagggctc tttactagtg
     1921 aattctgatt ttgaggaatg aagtcgattg attggtgaaa ataccccaaa ttgcaaccac
     1981 cttaaactga gctccgcatc tttgtaacct tgcatgtgcc ccccaatatc atggctccac
     2041 caagtatagc caatatttga agctgtactc gtaaaataag gctgaaaatc caagcttgcc
     2101 catgaaatga ctgaatctcc cgaaaatcct aaaggatatc gatgactccc gggtccagca
     2161 taacggctca agatgatatt atttttatgc ttcttttgag cattttgata ttgataatga
     2221 ttgagtaacc aaagtgggtc aactcctgat ttagagattg ccccttgttg ccaatcaatc
     2281 caccaaaaat caacgccttc tttttctaaa ggtccatgaa cctcttcaaa ataagctttt
     2341 cgaaatttta gattgtcaaa atcaaatttt gctgcctctt ctaattctgt atttaaatcc
     2401 agcgtttgag caacctgtgg ataagggtct tcaaaagcac gaattccatc agctggatgg
     2461 tcattcaaag ttactttcag ttttctttga tgcaattcat caataaaatt ttctggatta
     2521 ggaaataact ttttattcca tgaatagcct gtccatccag aaccaaaacg acttggaacc
     2581 tctgatactt tatgccaatc catatcaatc acactgacag ataagggaac tttcttatca
     2641 gtaaatttat ccatcaaagc caaatatgat ttatcactgt aatcgtaata ccgactccac
     2701 caatttccca aagcaaaccg aggaagcttt ggtgtgttcc ctgtcagctg ataaaaatct
     2761 ttcagagctt gtctataatc ccgtccataa gcaaataaat ataaatcaat tgtgctgaca
     2821 gaattaccag caatatctcc tacttctgtc agaacttttc ctttatccgc aaggactgca
     2881 aaaccatttt tagacataat cccatcctct aaaggacatt caccatcaat catatccaag
     2941 gttctagttg ttccttttaa attcccatca gatttttcac caaaatacca gcgatttgaa
     3001 taaacagaaa agttaaattt tacatcagca aataaactcg catttgtaaa ttctccacca
     3061 ttgtaataaa gatgaaccgt tgaggtgata atttcaatcg tctcttcttt ttcaatgata
     3121 tcaaaattga cctcagaaaa ctctcgattt tgtaccattt gtgtcattct ttcttcaaat
     3181 tcaccggtct cactatactc aatacgaatc aagtgctcag tcaaaaccgt gaatctagct
     3241 ttatcaaatt ttataatatt attattcata tatttacttt ctaattcact gaccatcctg
     3301 tcagtagata tctcactata atctaatgag tcactctttc aattctgtca aaaacttgtt
     3361 taatcatgat tgaattgaca agattaatca cagaaaagcc accaaaagtt aagaaataaa
     3421 tcattgtcag taaagcgtac ggacttgtaa agctgaaata gataatgaaa ccattaaaaa
     3481 tcagtaaaaa taaactttga aaccaatttt gaatacttat caacagaata ttataaactg
     3541 tttttttcaa agaattttta tatcttccaa tataagaaaa tccataaacg attagtaaag
     3601 caagaattaa agtgcctata aaagctgccg ttctcattaa aaatgacaac aataatggca
     3661 aatgacccac taaacgaaaa tcacagaata aaataaaagt cagcaaactt aaagtggtaa
     3721 aaaaaattgt cgcttgttta aaatttattt tgaagctttt aaaataattt ttgaccacac
     3781 ttcctctttt ttgatgcaat attttttgta aactcgtttg caaggcgcaa aaactcgctc
     3841 cgatagtaat cactggaagt gacgttaaaa taaataaagt attcaggatt atcaaatctg
     3901 caaaaagcgc cattattctc attactgaac tgtcaatatt taatagtttt cccatcttat
     3961 tcatcctttt ttactgataa gctgtccgcc acttttaata atagaccaga ggtttttaga
     4021 cctctggtct tttataacaa gctatttttt caaagctttt tggtaacgtt cataagcgtc
     4081 cgtttgtatt ttcaaatagt cttttaggcc catttgattt aattttgcaa tataagcctc
     4141 ccaatcctta tcaatcccac ctttagtaac ccattttgct gtttcttgtg ttgtgtacga
     4201 actcaaatct ggataaactt gagcaatttt ttgtaattca tcatttgtat aagtaaccga
     4261 aggaaaggca ggtcgagcat attgtttcaa ctctgcatcc atttttaatt tctgagcatc
     4321 accattgtta gggtcttcaa aagtaacctt atcattcaaa ctgttatccc atgatttagg
     4381 cccaaaatct cgcaaggaat ttatccaagc ttgagtgtct gctgagttat tcccagttgg
     4441 ttttaaaact ttgtaagcct cacctgattt ttcagtccca actccaaatg ctccataata
     4501 attttgaatg gctgcatcgt tagtataaaa tttatcagcc cactttatca gtgcttttac
     4561 atttttagca tgagtcgtta ccataaattc atctcgccct tggttaaaat ggtcagggtc
     4621 agacatcaca tattgatttc catcagggcc ttttaatgca ggcaaggcaa cataatcttt
     4681 agcatttttc ccaaaagttg catcagctgt ccaaccaact gacacaccaa ctgtttcagt
     4741 atcggccatt aattttgctt gtgcttgcgt agggtctagc gtgtacaatt ctgggtcaat
     4801 caaccctttc gtataggcat cattcatggc ctcaatccct tttttgaaat tatcagtcga
     4861 gcggatataa gctggttttc cattcaacat catcatttca tttgaattat cagctcctct
     4921 tagaacacca aagggtaagg tgtaagacat agtggggtca aaattgcctg ttccataagg
     4981 aatttcatct gccttcccat tgccattagg gtctttagtt ttaaaagctt ccaaaacttt
     5041 cacaaattcg tcataagttg ttggcatttg taagcccagc ttatccagcc aagctttgtt
     5101 gataaataat tgattcgcaa tgattggacg cattggggct tctttaggta aagaccaaat
     5161 atgaccatcc ggacttgtaa tcatggcttt taaagccgga ttcttcttca ttgccttttg
     5221 caaattaggt atatccttga catatttttc caagggaatg aaattagact gattttgagc
     5281 aatttcttgg tctgtaaagg tgattgaacc cataaaagta tctggtaaat tccctcctgc
     5341 catcaatgtt gacttcttat ctccccaatc cgcattgaga taagtatccc acttcacatt
     5401 aattccagct tcttttgcta actgatttgg aaatttagta taatcattcc cccaatcagc
     5461 ccaacgaact gttgcaactg taaaatcttt attgcttgaa ttcccctctt tactagagct
     5521 tgagtttcca caagcagaaa gtaaagcaag tgctgcgagc attgaagccg ctccagctgc
     5581 aacaaccatt ttttgatttt tcatttgaaa atctcctata atttaatttt aaaattacta
     5641 attaattcct aattcaatct aataacttac tctttaatcg ctccaaccat gacaccttga
     5701 ttaaaatatt tttgtaagaa aggataaacc atcataattg ggagtgtaga aacaacaata
     5761 gctgcatatt tcatcatatc agcagtttga cgaagttgtg aggctacgtc accagtagct
     5821 tgactttgga gcgtttggtt tgtaatcaat aattgtctta atattaattg caagggttgc
     5881 agattttggt cagtaagata aatcaaagca ttgaaccatg agttccaaat tccgactgct
     5941 gtccaaagac cgataactgc caaaatcgct tttgacaaag gaagaacaat ttggaaaaaa
     6001 tatctaaagg tactcgagcc atcaacttga gcagcttccc aaagaccatt tggaatagac
     6061 tcctgaaaaa aggtccgagc aacgataata ttataagggg aaaccgcaaa gggaacaatc
     6121 atgacccaaa ccgtattcaa gagtccaaaa tttttggtca ccaaataaat tggaatcaat
     6181 cctcctgtca caaacatagg aacaacatag agtagcgaaa tccattttct tccaaataaa
     6241 tctcttcgtg ataaggcata accgacaggg atattaacca ataacccaaa tgctgtccct
     6301 gcaactgtat ataaaatagt attaaaatag gaacgccaaa ttaagggctg agcaaatagg
     6361 gttttatagc cctctaaact ccaagatttc ggccaaaacc aaactgacgt taagtcaagt
     6421 ttttagagta acaaacgtag aattttaatc tatttatttt aagcacttac cttttcaaat
     6481 tgattaggtg taagataccc taaactttga tggattcgtt ttgaattata aaaggcttcg
     6541 atgtaccaga aaatactctg ataggcttct tcaaagttct tatatttaaa ttggtacacc
     6601 cactctcttt ttaaatgtcc atgccaagat tcaagactgg cattatgata agggtatccc
     6661 cttcgactga aagagtgagt catcccataa tacttaagca actcttcata ctctagactc
     6721 gtatactggc ttccttggtc agaatgaaga ataacagctt ctggatagtc ttgtgattta
     6781 atggccttat ttaaagttct ttgcactaat tctacagtca ttcgcttgcc caaatcccaa
     6841 gcaatgactt ttttagtata acgatccata atggttgaga gataagccca tccttgttga
     6901 gtaggaatat aagtaatgtc ggttgaccaa accttatttt tctttgtagg ttcagtctgt
     6961 atgagatttt ttcgattgat gtgatcactt agtgagtatc caggcttaaa tttcttaatg
     7021 actacagact tgagttgaag ttgcttcatt agcttctgta ccagttttaa cccgactttt
     7081 tccccttgct taagtagaag atgatgaatt ttaggagcac catagattcc tcggttagca
     7141 ttgaagagtt gagaaatttt gagtgacagg tattgtctcc ttaattgagt tttagatgga
     7201 tgtcggttaa tccgttcata ataacttgat tcaggaacat caaggagttg acagcttagt
     7261 ctgacattga gtgctaaagt ttgtatggtt tgagccatat ccgcagcact cacttctttt
     7321 tctcggcgaa tatggtcaat acttttttta agatgtctcg ttcttcctta actttagcca
     7381 attgtctttt taattctaga aaatcagctt tagagatgga gctttcatta gatttagagt
     7441 agaggtctat ccatttataa attgttgcag gggccacgtc gtattcttta gacagctggg
     7501 tgacggattg accagaatga tagaaggcga caagggtttc tttaaattct tttgagtagc
     7561 gttttttcat
//
