LOCUS       NZ_DS990119            28955 bp    DNA     linear   CON 06-OCT-2022
DEFINITION  Phocaeicola plebeius DSM 17135 Scfld_02_2, whole genome shotgun
            sequence.
ACCESSION   NZ_DS990119 REGION: 268931..297885
VERSION     NZ_DS990119.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN00000028
            Assembly: GCF_000187895.1
KEYWORDS    WGS; RefSeq.
SOURCE      Phocaeicola plebeius DSM 17135
  ORGANISM  Phocaeicola plebeius DSM 17135
            Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae;
            Phocaeicola.
REFERENCE   1  (bases 1 to 28955)
  AUTHORS   Sudarsanam,P., Ley,R., Guruge,J., Turnbaugh,P.J., Mahowald,M.,
            Liep,D. and Gordon,J.
  TITLE     Draft genome sequence of Bacteroides plebeius (DSM 17135)
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 28955)
  AUTHORS   Sudarsanam,P., Ley,R., Guruge,J., Turnbaugh,P.J., Mahowald,M.,
            Liep,D. and Gordon,J.
  TITLE     Draft genome sequence of Bacteroides plebeius (DSM 17135)
  JOURNAL   Unpublished
REFERENCE   3  (bases 1 to 28955)
  AUTHORS   Fulton,L., Clifton,S., Fulton,B., Xu,J., Minx,P., Pepin,K.H.,
            Johnson,M., Thiruvilangam,P., Bhonagiri,V., Nash,W.E., Mardis,E.R.
            and Wilson,R.K.
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2008) Genome Sequencing Center, Washington
            University School of Medicine, 4444 Forest Park, St. Louis, MO
            63108, USA
REFERENCE   4  (bases 1 to 28955)
  AUTHORS   Fulton,L., Clifton,S., Fulton,B., Xu,J., Minx,P., Pepin,K.H.,
            Johnson,M., Thiruvilangam,P., Bhonagiri,V., Nash,W.E., Mardis,E.R.
            and Wilson,R.K.
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2008) Genome Sequencing Center, Washington
            University School of Medicine, 4444 Forest Park, St. Louis, MO
            63108, USA
REFERENCE   5  (bases 1 to 28955)
  AUTHORS   Fulton,L., Clifton,S., Fulton,B., Xu,J., Minx,P., Mardis,E.R. and
            Wilson,R.K.
  TITLE     Direct Submission
  JOURNAL   Submitted (27-MAY-2008) Genome Sequencing Center, Washington
            University School of Medicine, 4444 Forest Park, St. Louis, MO
            63108, USA
COMMENT     REFSEQ INFORMATION: The reference sequence is identical to
            DS990119.1.
            
            On Mar 3, 2009 this sequence version replaced NW_002063610.1.
            Bacteroides plebeius (GenBank Accession Number for 16S rDNA gene:
            AB200217) is a member of the Bacteroidetes division of the domain
            bacteria and has been isolated from human feces. The sequenced
            strain was obtained from Deutsche Sammlung von Mikroorganismen und
            Zellkulturen GmbH (DSMZ)(DSM 17135).
            
            We have collected 7.9X coverage in plasmid end reads and 454 reads.
            We have performed one round of automated sequence improvement
            (pre-finishing), along with manual improvement that includes
            breaking apart any mis-assembly, and making manual joins where
            possible. Manual edits also are made where the consensus appears to
            be incorrect. All low quality data on the ends of contigs is
            removed. Contigs are ordered and oriented where possible.
            
            Sequencing/Assembly: The genomic DNA was purified from liquid
            culture derived from a single bacterial colony. A hybrid sequencing
            strategy that utilized reads from both 454 GS-20 and ABI 3730xl
            sequencers was devised and implemented to generate the draft genome
            sequences. 454 reads were assembled using Newbler (454 Life
            Sciences) into 454 de novo contigs. These de novo contigs were
            converted in silico to 800 base paired reads ('superreads') with
            400 base overlaps with neighboring superreads.  Finally, PCAP
            (Huang, et al, Genome Research, 13:2164, (2003)) was used to
            assemble the super-reads and the conventional 3730xl capillary
            reads.
            
            This sequenced strain is part of a comprehensive, sequence-based
            survey of members of the normal human gut microbiota.  A joint
            effort of the WU-GSC and the Center for Genome Sciences at
            Washington University School of Medicine, the purpose of this
            survey is to provide the general scientific community with a broad
            view of the gene content of 100 representatives of the major
            divisions represented in the intestine's microbial community. This
            information should provide a frame of reference for analyzing
            metagenomic studies of the human gut microbiome. Further details of
            this effort are described in a white paper entitled 'Extending Our
            View of Self: the Human Gut Microbiome Initiative (HGMI)'
            (http://www.genome.gov/Pages/Research/Sequencing/SeqProposals/HGMIS
            eq.pdf). These studies are supported by National Human Genome
            Research Institute.
            
            For answers to your questions regarding this assembly or project,
            or any other GSC genome project, please visit our Genome Groups web
            page (http://genome.wustl.edu/genome_group_index.cgi) and email the
            designated contact person.
            Bacteroides plebeius (GenBank Accession Number for 16S rDNA gene:
            AB200217) is a member of the Bacteroidetes division of the domain
            bacteria and has been isolated from human feces. The sequenced
            strain was obtained from Deutsche Sammlung von Mikroorganismen und
            Zellkulturen GmbH (DSMZ)(DSM 17135).
            
            We have collected 7.9X coverage in plasmid end reads and 454 reads.
            We have performed one round of automated sequence
            improvement(pre-finishing), along with manual improvement that
            includes breaking apart any mis-assembly, and making manual joins
            where possible. Manual edits also are made where the consensus
            appears to be incorrect. All low quality data on the ends of
            contigs is removed. Contigs are ordered and oriented where
            possible.
            
            Sequencing/Assembly: The genomic DNA was purified from liquid
            culture derived from a single bacterial colony. A hybrid sequencing
            strategy that utilized reads from both 454 GS-20 and ABI
            3730xlsequencers was devised and implemented to generate the draft
            genome sequences. 454 reads were assembled using Newbler (454 Life
            Sciences) into 454 de novo contigs. These de novo contigs were
            converted in silico to 800 base paired reads ('superreads') with
            400 base overlaps with neighboring superreads.  Finally, PCAP
            (Huang, et al, Genome Research, 13:2164, (2003)) was used to
            assemble the super-reads and the conventional 3730xl capillary
            reads.
            
            This sequenced strain is part of a comprehensive, sequence-based
            survey of members of the normal human gut microbiota.  A joint
            effort of the WU-GSC and the Center for Genome Sciences at
            Washington University School of Medicine, the purpose of this
            survey is to provide the general scientific community with a broad
            view of the gene content of 100 representatives of the major
            divisions represented in the intestine's microbial community. This
            information should provide a frame of reference for analyzing
            metagenomic studies of the human gut microbiome. Further details of
            this effort are described in a white paper entitled 'Extending Our
            View of Self: the Human Gut Microbiome Initiative (HGMI)'
            (http://www.genome.gov/Pages/Research/Sequencing/SeqProposals/HGMIS
            eq.pdf). These studies are supported by National Human Genome
            Research Institute.
            
            Coding sequences were predicted using GeneMark v3.3 and Glimmer2
            v2.13. Intergenic regions not spanned by GeneMark and Glimmer2 were
            blasted against NCBI's non-redundant (NR)  database and predictions
            generated based on protein alignments. tRNA genes were determined
            using tRNAscan-SE 1.23 and non-coding RNA genes by RNAmmer-1.2 and
            Rfam v8.0. Gene names are generated at the contig level and may not
            necessarily reflect any known order or orientation between contigs.
            
            For answers to your questions regarding this assembly or project,
            or any other GSC genome project, please visit our Genome Groups web
            page (http://genome.wustl.edu/genome_group_index.cgi) and email the
            designated contact person.
            
            Annotation was added to the contigs in September 2008.
            
            This is a reference genome for the Human Microbiome Project. This
            project is co-owned with the Human Microbiome Project DACC.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 10/05/2022 09:16:28
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.3
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Genes (total)                     :: 3,688
            CDSs (total)                      :: 3,591
            Genes (coding)                    :: 3,539
            CDSs (with protein)               :: 3,539
            Genes (RNA)                       :: 97
            rRNAs                             :: 6, 5, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 5, 6 (16S, 23S)
            tRNAs                             :: 78
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 15 of 52
            Pseudo Genes (incomplete)         :: 43 of 52
            Pseudo Genes (internal stop)      :: 4 of 52
            Pseudo Genes (multiple problems)  :: 8 of 52
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28955
                     /organism="Phocaeicola plebeius DSM 17135"
                     /mol_type="genomic DNA"
                     /strain="DSM 17135"
                     /isolation_source="biological product [ENVO:02000043]"
                     /host="Homo sapiens"
                     /type_material="type strain of Bacteroides plebeius"
                     /db_xref="taxon:484018"
     gene            complement(1..4227)
                     /locus_tag="BACPLE_RS02415"
                     /old_locus_tag="BACPLE_00983"
     CDS             complement(1..4227)
                     /locus_tag="BACPLE_RS02415"
                     /old_locus_tag="BACPLE_00983"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: protein motif:HMM:NF014567.2"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hybrid sensor histidine kinase/response
                     regulator transcription factor"
                     /protein_id="WP_050792054.1"
                     /translation="MGANAPKFRTLTMENGLLHTDVTCVTQDVNGLIWIGTNGGLQSF
                     DGYNLQSYEYYKPTDRIRYLHDRITSLATDSCNLWIGTESGLLRFNYNQGNYADFELS
                     ADLQVLSSTLVDKVYATEEGVLWVVTSDSMYVVNVDRKRNLLSSYGKESEVLSAKKNV
                     HTIVKNGDYTWLCTPDMLLQVKLTQGRVKIVNSYKCREISRRNEASSSLYIRDNFLYL
                     RVSSGCARFPLNTDGSLNLSRYDFYDFHSLNAHIPQHTSGKLIVDRSNTLWCASNIGL
                     LQISTNSGKVYADIHARQSAYTTSISSNFISTLFIDSFHNLWIGTWGKGLNYVSLSMP
                     LFGTVYDNPSNEYSIKGTFVKGIERSSDGTLWLLTQKQGLNKYRTDEGLLMFTDFSQF
                     LGKGNVFKALKFSKNERILYVGLINGLVAYDVKSNSMSYVIFNNEKALVKAAVDITRM
                     EYDANGFLWVGTWRNGIYCFKEDNGALTFVKHIGLRDGLKSTCVPYLFFDKEKNEMMA
                     CTRKGLSRFILQGTDSDIKKVVSYGVDLKNSHSLSNNFLACIDKQNDSIYWVGTLGGG
                     LNRLVINGDTDNAYSATSYMTQDGMMSNDAEIVMVDKNNNVWIGGYGIMKLDTQTGIL
                     SRFDYLDGLQGNFFKYGAGYKGKDGMMYMGGIDGLSYFYPNHVQTGNEKYQLYLSNLY
                     VHGERIRVGEKINGVVVLPEILDKLEKLTLHHDQNDFSIEFSALGYRLSNRIMYRYKL
                     GGYDAEWREVPVSENKVLYSNLDYSTYDFELQYSTDNGQTWNPVSKKLQIEVLPPWWL
                     SPWAKITYLIFTFSLVLFIFYLYVQELNMKHKISLHDMEKQKDEENHQLKLQFFMNIS
                     HEFKTPLTLILSSVERMEDEFSRTVGQVPQKIQESFNSVSRNANRLLTMITELVDFRK
                     SDLNIADLNLQEDRIDKYVLQIVQEFSPWALRKKIEFTTSVQENVLMKFDLEKFSMVL
                     TNLLSNAMKYTSNGGRVEVSLTTGTDVAPSPKYENSFQVGDTIWGEEVCILKVSDTGV
                     GISAETISKIYDRFFQIRDNSSVHLGSGIGLAIAKNMVLLHGGNIIVSSERMKGTEFI
                     VTLPMRLKEEVQDKNNTFDVHGYLQSVHVEYNYDMEPQKASVDEDKEAADASDRQTLL
                     LVEDNVELLSMLKEHFQIKYHVITAENGEEGLRKCTEFYPDLIISDVMMPLMDGIEMC
                     KAIRNNLSIAYTPIILLTAKSTVENQIEGYESGADLYLPKPFSMKILELNVARLLAQK
                     LRMMQTEHTQAMPVDVNPEEQTEGQEQAEPEVTRKSIKSEKDKEFIESLNGFLENNIS
                     NPDLSVDMLCKHFGLGRTRLYAMVKEISGQSLGDFIRDMRLNKAAYLLKHTDMNITEI
                     IYETGFGSNSHFSKVFKNKFGITPSDFAKQ"
     gene            complement(4547..6031)
                     /locus_tag="BACPLE_RS02420"
                     /old_locus_tag="BACPLE_00984"
     CDS             complement(4547..6031)
                     /locus_tag="BACPLE_RS02420"
                     /old_locus_tag="BACPLE_00984"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_081458090.1"
                     /translation="MRTKVLLFIVCLCISWMNSIYAGNKTATLVTYPEKNLRVQQSEL
                     YRVYLNDDTDNDVTIFKNVCNTYFKGMPGQRKNDDKPLTKFKGRSIHWGHFSFQGKVK
                     VTVRVNKDIEGKKIKVYPSRHDIKVNKQDANCFSFMLDRPGQFSVEIGEDGYKEGLLI
                     FADPMETDVPADLSKWKVIEKGDKTLLSTLSVKDSALYFKKGVHDIGVYKVPSNIKRI
                     YLEGGAWVFGSFIMDGKACSNVKIYGRGVLSGARLHLRESHMVEAKNGADGIIVDGIV
                     IADYSFFAVRLLGTDNEVAWTKIVGGWIYNCDGIAAYANSTIRNCFIWANDDNIKIYR
                     DNIVVEDVVCWQLDNGAIFQLNWSNSVARNCRVSRVDIVRAEWDSDRPNNGILSCRNG
                     GGADEGFVFEDVRTDTPVTHIFRLSPLGDKDQLIKNFLFKDWDVWVDVSKGKKNYMEG
                     VKGQTPLSGLIFENFRVNGKVLTEKSMHEMLRWSILNCEKIDFR"
     gene            6215..8047
                     /locus_tag="BACPLE_RS02425"
                     /old_locus_tag="BACPLE_00985"
     CDS             6215..8047
                     /locus_tag="BACPLE_RS02425"
                     /old_locus_tag="BACPLE_00985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007480018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 2 TIM barrel-domain
                     containing protein"
                     /protein_id="WP_148374629.1"
                     /translation="MRKFIFLLCCCVCFSAYAQKWEMKQAPLMTPWSKNIDIHHVLPE
                     YPRPLMQREDWKNLNGVWEFEMREEGDRLPAKRKLHEKILVPYPWESALSGVRRQLST
                     QRAWYKRTFTLPKEWKGKNIILNFGAVDWESEIYVNGKLVGTHKGGYDPFSFNITSYL
                     DLSAKEQELIVSVYDPGNSKAIPHGKQNNTRFSEPKGYSYSPSSGIWQTVWIEPVNKD
                     HVTAIHTIPDFDKKAFHVEVNASGNQNLKVNICIQSQGKTESQHSGALNTPITLPLQT
                     IRPWSPDTPHLYDVIVKLTNEKGETVDSIRSYAGMRKISLKNENGVQRLALNDKFIFQ
                     MGPLDQGYWPDGIYTAPTDEALKWDVQKIKEWGFNMIRKHIKVEPQRWYYWCDKLGIL
                     VWQDMPNCFKTRNEEEKEQFETELQRMIRTHWNHPSIVNWIVFNEHWGIYDCERITEN
                     VMKLDPSRLVTGNSGIDARKPSIDYEVGHIKDNHSYRPPHVPLISSKRATVNGEYGAI
                     GYKIEGHIWDTDGPWVHHNYKNKENATKEYVKFIQQINEYIRRGLSAAVYTQWTDVEN
                     EMNGLYTYDRKVEKLDKQKVSDANRSTYTEKEQIKGQTDAQYIQ"
     gene            8065..9495
                     /locus_tag="BACPLE_RS02430"
                     /old_locus_tag="BACPLE_00986"
     CDS             8065..9495
                     /locus_tag="BACPLE_RS02430"
                     /old_locus_tag="BACPLE_00986"
                     /inference="COORDINATES: protein motif:HMM:NF013080.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfatase"
                     /protein_id="WP_007558596.1"
                     /translation="MNSIKLISLAALATSLMPSWAAQKQNKPNIIFVISDDHSVPFLG
                     CYGNKDIKTPNFDKFASEGMTFTRTYVTAPQSAPSRSSFFTGRSTISTTMSMFSLPLP
                     GNVITYPDILKEHGYYIGVTARSHHQDGLKRNKDIQQAIERNDMATFGRRFDYHRIGG
                     QPLPELKVFLDKAATEGKGKPFYVQVSFYDPHRPWDKNAIPEPHDPNTINLPDNYPDN
                     ALIREDFARHYDEIARMDTQFGLMMEELEKRGLADNTIVVFVGDNGSALLRGKGTLYE
                     TGINVPLIVRWPGKIKPGSYSNVLVSGEDFAPTLLELAGYKADPKMTGHSFAHTLLGK
                     AGTDRTWVFSARGAHAEDLPVTTKDFDLIRAIVTDRYKLIYNPVRELPYWPVDFSHEP
                     FWLDLVEQNRTGFIPREWKERYFSERPMFELYDLKNDPQELHNLAGLKEYAEIEKKLR
                     DTMAEKMLVDRDYVPLPFYSLDKEYK"
     gene            9589..11025
                     /locus_tag="BACPLE_RS02435"
                     /old_locus_tag="BACPLE_00987"
     CDS             9589..11025
                     /locus_tag="BACPLE_RS02435"
                     /old_locus_tag="BACPLE_00987"
                     /inference="COORDINATES: protein motif:HMM:NF027814.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 27 protein"
                     /protein_id="WP_007558600.1"
                     /translation="MKNKTFLSAALAFFMLAGFNQTTQAITPQMPSEETVSKCKVAPT
                     PPMGWNSFDAYDCRINEQEFKAIVDYMAANLKQHGWEYAVIDYCWFNDNPGGWNNPSK
                     RYGHPDIRLDKDGKPLDVLCMDEYSRLIPSVKRFPSAANGKGFKPLADYVHSKGMKFG
                     IHIMRGIARQAYFQKSKIMGSKATAYDIAEPFDTCNWCNNMYGVDASKEGAQEYYNSI
                     FKLYAEWGVDFIKADDTMYPPYHKGEIEMMRKAIENCGRPMVLSLSCGEAPLGRAEHI
                     KKNATMWRVSADFWDNWEDLYHNFDLLNAWSSHIGEDSWPDADMIPFGKLALQNRPVG
                     KERMSRFTPEEYNTLMTLFCMARSPLMIGADLLSTPKEIIDKYFKNDEILAIDQHSTD
                     NRQVFKNKSYAIWTATVPETGERYIALFNLQDKPATVTFNMELESLRGKYQARDLWKK
                     QNIGIVEGKLSAQLGAHDATVFKLTKVK"
     gene            11043..13022
                     /locus_tag="BACPLE_RS02440"
                     /old_locus_tag="BACPLE_00989"
     CDS             11043..13022
                     /locus_tag="BACPLE_RS02440"
                     /old_locus_tag="BACPLE_00989"
                     /inference="COORDINATES: protein motif:HMM:NF016497.2"
                     /GO_function="GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 43 glycosylhydrolase"
                     /protein_id="WP_007558602.1"
                     /translation="MKKINILLIGIFITFHTLYAQTPLWQGKGRIAISSDGNEHDDDD
                     WAATPLSLAMIAAKGLQDKLVLYTYSDHIWGSNQDRPNKHGISAYEHMRLSALGSKKW
                     FGFHNSRFICAVDNAEIAYNAMRDVINASSAEDPLIIVAAGPMQVVGEALQRSDKEKR
                     QYVTLLSHSQWNNRHSDNPERKKGWDMHSGWTWDEMKAAFGTPEGGNVRFVQILDQNH
                     GKDYIGFFCPKENYDWIKTSPARNSPAYQPGAWDFLYERISTCIKKKGTCFDPSDAGM
                     IVYLFTGIEKTNPDMARQIMENPQFTYQNPIRSGIDPKGLRDCQVLKDQNTWYLTGTA
                     FPHWARQEQNGKLNQGVPLYKSTNLTDWTFVKYIVERPDSSKWYYNRFWAPEIHKIKG
                     KYYATFNCSNPKHGYPGQHIGYAVANSIEGPYKVITEEKPLANGNDLTLFEDEDGKVW
                     AFWNRGREFGIGYAQLDLETGKFLTTLQTAIQPGKVDYEYDKEGKLVHEPGYDGRPIP
                     KVKKYYSWDSIGIEGAYVIKENGQYYLFYSSWTRGYEIGYATASKITGPWKKYEGNPF
                     YGAQSKAACNRNGFTWKGDPYSPFNQVGHNEIFVGPDGRYWISCHGITHDAPESPSLV
                     IDPIWFDHDGNIKSNGPTYTLQQTNYLNNPTSKAK"
     gene            13133..14512
                     /locus_tag="BACPLE_RS02445"
                     /old_locus_tag="BACPLE_00990"
     CDS             13133..14512
                     /locus_tag="BACPLE_RS02445"
                     /old_locus_tag="BACPLE_00990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017140974.1"
                     /GO_function="GO:0008484 - sulfuric ester hydrolase
                     activity [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfatase-like hydrolase/transferase"
                     /protein_id="WP_007558604.1"
                     /translation="MKTKFMLSTLLAFPALSHAQTNFIIILTDDQGYQDIGCYGSPLI
                     ETPNLDKMAEEGLRLTNFYVSASVSSASRAGLLTGQLNTRNGVKGVGWPDSKGLPTDK
                     ITIANALKTKGYATGCFGKWHLGDLDGYLPTDRGFDYYYGIPYSNDMYIGYTHKFSPN
                     CVFTEGYNLDKALQDQQLVKRTKNKAQLKKELNYASPLFENKEVIEYPCDQATTTYRY
                     FNKAMEFIGKNKNQPFFVYLTPSMPHVPLFVSPQFKGKSKRGLYGDAVEEIDWNVGRL
                     LDFLEKEGLSENTMVIFTSDNGPWLGMKENGGSALPLRDGKFSAYEGGVRTPCIIKWK
                     NHIPAGKVSDHIIASIDIFPTLLELAQMDKSKYDLDGITLTKFISNPDNVEPRDRYLY
                     VKDGKIVGIRQNDWIYLPQTGLRVTPKGNFEQELFNIRMDIGQKSNLFKKETKKAQEM
                     EQLLQQQSH"
     gene            complement(14612..16669)
                     /locus_tag="BACPLE_RS02450"
                     /old_locus_tag="BACPLE_00991"
     CDS             complement(14612..16669)
                     /locus_tag="BACPLE_RS02450"
                     /old_locus_tag="BACPLE_00991"
                     /inference="COORDINATES: protein motif:HMM:NF017502.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Sip1-related alpha-galactosidase"
                     /protein_id="WP_007558606.1"
                     /translation="MSKKYVTFFVLMCLMWIQGIPSKAKDLNLSFSDSCAVFRTSVKG
                     KPVEGVLESYRIELPVYKKALFYASRFKGFDGINQNFSWPVDRLSALFDASFEPVPTI
                     DKPVNCGIFLVLELQDGSYWVVQPVAINSAMSWIEVVDDNHIDIKYGTMGTEEVDLKD
                     APVFAYGRSGDVYKVVNAIWSSLVKDKYIADNLKLRKDKVYPEPFKYLGWCSWEHFRK
                     NINEKVLLEAVDGIEKSDVPIRWVLVDHGHQTQVKDKLINFEVSPEKFPRGWSPLLSK
                     RSDKIKWFGLWHCMYGIWGGISANHKMDDLKPYLMKNDRGRIIINGSPEAADLFYNKM
                     VSSASDNDFDFIKIDVQTRDFNNYLMISNPVEAHHNNAAALERYAKKKLDGLMNCMAQ
                     NLPCAFNTKYSATTRVSVDYKLNSIPLARNHIYQGFQNTLWMGQTVWPDHDMFHSSDA
                     RLGRLMAVSKAMSAAPIYLSDPPKNFVDDYISPLAFSDGEILRPMAPGTSLPKSLFNN
                     VLTGDGVYYVIAPLTETSAAVVAYSLSNKNTKNITEVEVTAEDYTYADAMVQPYPGRR
                     ELPAEGLVYYDWYTKKGNVLKDKYAFNLKNMEDRLVLLCEIENGWSVIGLENKYLSPV
                     AVKKYKAEKNKLTVSLKENAPFVIYSDKPLLKCQYASYKKLDNGFYLVTPDSGKNQFV
                     MYK"
     gene            complement(16687..18060)
                     /locus_tag="BACPLE_RS02455"
                     /old_locus_tag="BACPLE_00992"
     CDS             complement(16687..18060)
                     /locus_tag="BACPLE_RS02455"
                     /old_locus_tag="BACPLE_00992"
                     /inference="COORDINATES: protein motif:HMM:NF012516.2"
                     /GO_function="GO:0004650 - polygalacturonase activity
                     [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase family 28 protein"
                     /protein_id="WP_007558608.1"
                     /translation="MKQRLLLMILCFATLCSDVVLAKVFVYPMADGIKKSSLFEIEVS
                     DGGEFLESPVYTNVAQWKTNRCKTTSWTSFATDTKPVVRVKTNAYKVEVCRILPRKYN
                     IACHILNDSTVEFKLPGPGQYSVEFEEGVAIAHPLLIFVDTYPLKKPAEHTPNLIVFE
                     KGIHEIGDNYMLKSNQTVYLAPGAYVKGQFVSDGQENITIMGQGIISGEEYPARSHNH
                     MIAFRNCNNVLIEGVTIINAPRFCVSLTGTNQICRNLKMMGWWFSTDGIGIGSNSLIE
                     DCFFKVNDDAIKLYRSNTIARRCVIWQMENGAPFQIGWNMPGYNTNFHVYDVDIIRVE
                     HPWDNPNEAVFDAIHGSNGIMTNYLYEDIRIDNCKHRLFHIMTKPNRFGSWDPERGEI
                     RNLTFRNIECYTEPEMRNIIMGHDSIHKVSNVLLENIKVNGKLWKNMSDANLLTNENT
                     TEGIIIK"
     gene            complement(18085..19089)
                     /locus_tag="BACPLE_RS02460"
                     /old_locus_tag="BACPLE_00993"
     CDS             complement(18085..19089)
                     /locus_tag="BACPLE_RS02460"
                     /old_locus_tag="BACPLE_00993"
                     /inference="COORDINATES: protein motif:HMM:NF016497.2"
                     /GO_function="GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 43 glycosylhydrolase"
                     /protein_id="WP_007558610.1"
                     /translation="MNLASFKCLFNKQIFLFLLVCLCLESALAGNPIRKGLPEYGIRD
                     CHVYVEKGRYYMVGTEIAPPGENKEGISLYESKDMKKWKKTALLVDRESIPADSWYKN
                     GFDSPEIHKINGRYVLCFGGRNNDVNPYGTTETVVAISDKIQGPYKIVTDKPIVKGNR
                     FTLWQDDKDGKVYAYWEKDGSLCGALMDTALTHLAGDPVVISIPRQFRKDDRFLDSPS
                     VLKYKGKIYLFYTVFKGGYYAANLVSESPLGPWKASDEILFYRSEDQAPTQLHGEYDN
                     PLVFAPPCEIIGNVQLFKGLNDKWYISYHSEDKYAEPFFCVDRVYPDENGFKCVITLP
                     "
     gene            complement(19138..19932)
                     /locus_tag="BACPLE_RS02465"
                     /old_locus_tag="BACPLE_00994"
     CDS             complement(19138..19932)
                     /locus_tag="BACPLE_RS02465"
                     /old_locus_tag="BACPLE_00994"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_007558613.1"
                     /translation="MPVWREKGLLAFTINLQGGSPEGYSETQPWHNSAILSDGSLDEE
                     YMKRLKLILDKADELEMVVILGLFYVGQEKFLDNAEAARNGIKNAVEWVLTNGYKNVL
                     LEINNECDFFKLDGLSPETVHESIEYAKSITYHGRRLLVSTSYAGKIVPSDKVIAVSD
                     FVLLHGNGVWKPERITLQVDSVRKSPAYTPKPMVYNEDDHFKFDKEVNNFVKATEAYA
                     SWGYFDFRKKDEPYEQGFQCIPADWGINSERKKGFFRLLTEWKKAE"
     gene            complement(19938..20237)
                     /locus_tag="BACPLE_RS19600"
                     /old_locus_tag="BACPLE_00995"
     CDS             complement(19938..20237)
                     /locus_tag="BACPLE_RS19600"
                     /old_locus_tag="BACPLE_00995"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_007558614.1"
                     /translation="MKHFFKQSFISTAFLSLLFVSCGTADVHKTEVSIVGEEFYINGK
                     PTFEGKTWRGMKIQGLLPNARLVNGILMTRRILRVINGRIRIRKYGMPTAIQESL"
     gene            complement(20274..21080)
                     /locus_tag="BACPLE_RS02470"
                     /old_locus_tag="BACPLE_00996"
     CDS             complement(20274..21080)
                     /locus_tag="BACPLE_RS02470"
                     /old_locus_tag="BACPLE_00996"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase"
                     /protein_id="WP_148374630.1"
                     /translation="MNEYRGWSNCIEISNAGTRVVISPQSGGRVLCYSVENENILFED
                     REFDGYLLENFRKDRHWPDGARFDIGPEAIPGKLRDEPFMGVWDYKIINEYTVELSFS
                     KDNRLGLHLKRTFTLDAHSSELYIRQSARNYTDKCLNRHFWGRYFCKGGGRVVLPLSD
                     NEVWGYMGNYQSDKVLTNNGKLCYNVSDETLKLGCNSRSGRISYLYKDLKFEVTFKVM
                     PQMDYSSTMGYTTIFYTNGKLCEIEPVSPLYKLSPGESFVFEQTWSLKKQ"
     gene            complement(21223..24147)
                     /locus_tag="BACPLE_RS02475"
                     /old_locus_tag="BACPLE_00997"
     CDS             complement(21223..24147)
                     /locus_tag="BACPLE_RS02475"
                     /old_locus_tag="BACPLE_00997"
                     /inference="COORDINATES: protein motif:HMM:NF014850.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 2"
                     /protein_id="WP_007558618.1"
                     /translation="MKKDVLLFALLTLSLYASSQTIDLSKQPWRLWLDETAEYFNDSL
                     YLPPYNMDVIPCTPPTCGWQNLYNNKNAVDITIPATVEEYMWGKNGNTYGINGNYCGV
                     SWFTTGVSVPADWKGKRITIDFESARMRAEVYLNDKLVGYELINGTPFSIDVTDDVKI
                     GSHNRLAVRITDPNGNFAWRDWDSFMWGKYEIPPSHGFGGITGKVSLHATSHSYIDDI
                     FIKNTPDLNRVSVMTTLENEGDLCNGVIEYSIKEYGTDKLVWKGKTVVPSWSKKACVE
                     KNIEVKNAKLWSPDSPNLYVLTAKWMNDKGEKHVKTERFGFRWFDVKTVNGDRMFMLN
                     GKRIVLHTAISWGHWPVNGIYPTTELARKHIMSAKQLGMNMLNFHRGIGQSCVFDLAD
                     ELGMLIYEEPGGYRPGNSAFARKWKREKLLRMVKRDRNHPSLVIVNMINESSRNPYPN
                     EVEDIREAHLLDPTRCITFTSTYFGAKLYKGVCPSTPAPIKMHMLPNDTTIHYQGWWD
                     QHHASGPGVYKDEFYKSPVDFSRYKKEKDEIIFYGEEGAIGTPPRLQLIKQEIEKGGK
                     RGWTGDDLLKQYHAFDAFIHEKGFTDAFPDVDSLCRSLGSVSYYYQGRMIENMYISNN
                     IDGWATNGWESTKLENHSGIVDIYRNHKADPAIIAYYNQPLYVAVKANKKVLEQNDTT
                     SVDFFVVNRKDLKGRYKLTVFLGNQANDAWTQKQEFQVAVKGGVIFGQLLKQHIRFKI
                     NQDGYTTIRAELSKHGKIVAQGAEQVFAVNNSPVAHPSVYVADTAGRMERVLQKAHIP
                     YQNIKIKDIISRMGTLVVGGKLQPGIVGGNFRQDDPLIEWVSRGGKLVILDNASEWCT
                     YLEQKEVADYRGSRLIGRDWFGGNFFVKNHALFNGLPQATAFNWEYQCFASYNRHREG
                     LRLENGECVVGCYADHKNELFSALTILPVGKGHIIISSLDFMKAVDNPVCVKLLNNII
                     AF"
     gene            complement(24264..25916)
                     /locus_tag="BACPLE_RS02480"
                     /old_locus_tag="BACPLE_00998"
     CDS             complement(24264..25916)
                     /locus_tag="BACPLE_RS02480"
                     /old_locus_tag="BACPLE_00998"
                     /inference="COORDINATES: protein motif:HMM:NF025680.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RagB/SusD family nutrient uptake outer membrane
                     protein"
                     /protein_id="WP_167535712.1"
                     /translation="MKSHNKIVQAFMFASLLTCGACTDLSDTVYSEITEESFSKNPSS
                     INLLIGKVYTSIGTYIAATNPNFSPFYYNVCTTDEMFIPFRNVTKEWNNAKFSDAYQH
                     SWTPTTQDLDKNWEKCFGIITSANMAIDQVNSFDGMEQHLKDVTIAEIRMARAYAYYL
                     LIDLWGDVPYTVSSSDKTSDIKKKTSAEIYNLMMKEFDDCLPLLKEAKKDKSTTYGKF
                     NYWAALALKAKYLLNAKIFLETDRVNPKYADEKTGLDECIDICDELMSPEAGFELEKD
                     YFTNFKAHNENSKENIFVIPFDAVYSKDNFTLGFGYARHCLHASQTPVYNGTVNGQNG
                     FSVYPSLYKTFEDFDVRKNGLNAGPQFDASGKPLKCIKAQMKNPDGTFMDLDFKVDFD
                     INNCDEMSGARFQKYEYENGIITDAMNNDFVVVRLADIMMMKAECLMRLADGQATQEA
                     VDLVNEVCNRSISDPSRYDFYDTSNLTMDALLEERRREFYGEALRRTDLIRFEKFTDM
                     DWVDDIHMDRSKIRTEKYRTVFPLPANYLKTAPQIEQHPYYQ"
     gene            complement(25935..28955)
                     /locus_tag="BACPLE_RS02485"
                     /old_locus_tag="BACPLE_00999"
     CDS             complement(25935..28955)
                     /locus_tag="BACPLE_RS02485"
                     /old_locus_tag="BACPLE_00999"
                     /inference="COORDINATES: protein motif:HMM:TIGR04056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent receptor"
                     /protein_id="WP_007558622.1"
                     /translation="MKQRIVFVMCLCFLLMNGVLAQTKSLKGTVKDKLGESIIGASVL
                     IEGTSQGTITDLDGNYVIENIPAGKNVLVVSYVGYQTQKLEINGRSVIDIVLQEDTEV
                     LDEVVVVGYGVQRKTDVTSAVASIKKENFTQTVTSSSPLQMVQGKIPGLAMSRAGGGD
                     PTSDMTLQIRGMSTINAGASPLIVIDGIPGGSMSTVSPNDIESIDVLRDGSAAAIYGS
                     RGTSGVIIITTKKGVADGKTKIEYDGNVSFDQVSSTWDLLSGDEYRSLKESMMNSSIK
                     LAQEKGQAMVDYGGNTDWMKEITRTAVSHQHYLSLNTSSKHSRTAASLTYNNYQGIVA
                     TSGKEEINGRISTEFKHFNDNLKVNLNLAYTSKTQVPIEKLALRQALFWNPTMTPYQE
                     DGSYTPGADPLIYNNPVNLINETRREDKYNTLMGNAKITITPFKGMTLTGMIGLDRTE
                     SSLAWYKTSKHEEMMMKGKSGEAYKKSALNETRTLELTAGYNRQLIDDLNFDIMGGYS
                     YQEFINEYLDATNYDFKFDDNGYNSIGSGAALKNGQASLDSYKGSSKLIAFFGRVVFN
                     YKDKYLFNATVRHEGSSRFGKNHQWGTFPAASVAWRIINEPFMKEQKVFSDLKLRLGY
                     GVTGNMIDQAYLNYVLFASQPIYAHNGSTSGNAYEPTYAPKTNANPDLKWETKKELNV
                     GLDMAFLGGRLNANIDIYQRKSEDLLYKYNVPVPPYLASEMWGNIGTISNKGVEIGIN
                     ATLIQKKNFSWSMNFNGSYNKNNVEKLTTADGDVQERYELNLASPMNGHWAVVTKVDA
                     PIGNFWGFKYAGVNENGETMVYQLNEDKSIAMGEDGKPLTLRWLDAKGSEDNKTIIGN
                     GMPKYYANMSHQFRYKNFDFSFLLRGVFGFDILNLGSAYQGSPTFNRVDNVLKSALTS
                     PIYDEPSITDAVVENGNFVKLDNITLGYNFPIKNNKFISSLRLYGSVQNVATFTSYSG
                     QNPELEINGTVVGVDNMDAYPVARTYSLGVKISF"
ORIGIN      
        1 ctattgcttg gcaaaatcag atggagtgat gccaaactta tttttaaaga ccttactgaa
       61 atgggaatta cttccaaagc ccgtctcata gattatctcc gtgatattca tgtctgtatg
      121 tttcaacaga taagctgctt tgttcaatcg catatcccgg atgaaatcac ccaatgactg
      181 tccggaaatc tccttcacca tggcataaag tcttgtccgg ccaagcccaa aatgcttgca
      241 cagcatatca acagaaagat ccggattcga tatattattt tccaggaatc cgttcagact
      301 ttctataaac tccttatctt tctccgactt tatggatttg cgggttactt ccggttctgc
      361 ctgctcctgc ccttccgtct gttcttccgg atttacatcc acgggcattg cctgtgtatg
      421 ttctgtctgc atcatccgga gtttctgtgc cagaagtctg gctacattaa gttccaatat
      481 cttcatggag aaaggtttgg gaagatacaa atcggctccc gattcataac cctcaatctg
      541 attttctacc gtactttttg ccgtaaggag aattatcggt gtatatgcta tcgacaggtt
      601 atttcggatg gccttgcaca tctctattcc gtccattaac ggcatcatca catcactgat
      661 aattaaatca ggatagaatt ccgtacattt tctcaacccc tcttctccgt tttccgcagt
      721 aatcacatgg tattttatct ggaaatgctc tttcagcatg gacaacaatt ccacgttatc
      781 ctccactagc aacagggtct gcctgtccga ggcatctgcc gcttccttat cttcatctac
      841 cgatgctttc tgaggttcca tatcatagtt atattctacg tgaactgatt gcaaatagcc
      901 atgcacatca aatgtattat ttttatcctg cacttcttct ttcaatctca tgggcaatgt
      961 gacaatgaat tccgtaccct tcatccgttc actgctcaca ataatgttcc caccatgtag
     1021 aagcaccatg ttcttggcaa tggcaagtcc tatacccgaa cctaaatgta ccgaagagtt
     1081 gtctcttatc tgaaagaaac ggtcgtaaat cttactgatt gtttccgcag agattccgac
     1141 tcccgtatcg gaaactttta agatacaaac ttcttcgccc catatcgtgt cgcccacttg
     1201 gaaagagttt tcatatttag gagaaggagc cacatctgtg ccagttgtaa gagacacttc
     1261 cacacgccct ccattggacg tatatttcat ggcattggaa agcaggtttg tcagcaccat
     1321 ggaaaatttc tccagatcaa atttcatcag cacgttctcc tgcaccgagg tggtaaattc
     1381 tattttctta cgcagggccc agggagaaaa ttcctgcaca atctgcaaca catatttatc
     1441 aattctgtct tcttgcagat tcaaatcggc aatattcagg tcactctttc tgaaatctac
     1501 cagctctgta atcatggtca gcagtctgtt ggcatttcgg gataccgaat tgaatgactc
     1561 ctgaattttc tgtggcacct gcccgactgt ccggctaaac tcatcttcca ttcgttccac
     1621 tgacgacaga ataagcgtta aaggcgtctt gaattcatga gagatattca tgaagaactg
     1681 caatttcaac tgatggtttt cttcatcctt ttgcttttcc atgtcatgca aggatatttt
     1741 atgtttcata ttcagttcct gcacatacag gtagaagatg aacagcacca gtgaaaaggt
     1801 aaatatcaga taagtgattt tagcccacgg agaaagccac caagggggca gcacttcaat
     1861 ctgcagtttt ttacttaccg gattccaagt ctgtccatta tccgtagagt actgcagttc
     1921 gaagtcgtaa gtggaataat ccagattgga ataaagcact ttattctcac tcaccggcac
     1981 ttcccgccat tccgcatcat atccgcccaa tttataccga tacataattc tgttcgaaag
     2041 acgatagccc aaggcagaaa attctataga gaaatcattc tggtcatggt gcagtgtcaa
     2101 cttctccagt ttgtccaaaa tctcaggaag cacaaccacc ccatttatct tctcaccgac
     2161 ccgaattctc tctccatgaa catataagtt tgacagataa agctgatact tttcattccc
     2221 agtctgcaca tgattgggat aaaaatagct caaaccatct attccaccca tgtacatcat
     2281 tccgtccttt cctttgtaac cagctccata tttgaagaag ttgccttgca atccgtccag
     2341 gtaatcaaat cgagaaagaa tgccggtttg tgtatccagc ttcataatgc catagccgcc
     2401 aatccacaca ttgttattct tatctaccat cacaatttcc gcatcattgc tcatcatacc
     2461 atcctgcgtc atgtaagacg ttgcagaata ggcattgtct gtatctccat tgataaccag
     2521 acggttcagg cctcctccca atgttccgac ccagtaaatc gaatcattct gtttgtcaat
     2581 acatgccagg aagttattcg ataaggaatg agagttcttc aaatctactc cataagaaac
     2641 cactttttta atatcagaat cggttccctg caagataaat cgagaaagcc cttttctggt
     2701 acatgccatc atttcgtttt tttctttatc aaaaaacaaa taaggtacac aagttgactt
     2761 caagccatcc cgtaaaccta tgtgtttgac aaaagtaagt gccccattat cttctttaaa
     2821 gcaatagata ccatttctcc aggtacccac ccacaggaag ccgtttgcat catattccat
     2881 tcgagtgatg tctacagcag cctttaccaa tgctttttca ttgttgaaga tgacatacga
     2941 catcgaattt gattttacgt cataggccac aaggccattt atcagtccca cataaagaat
     3001 acgttcattc ttactaaact ttaaagcctt aaacacattt ccttttccca ggaattgaga
     3061 aaagtctgta aacatcagaa ggccttcgtc cgtacgatac ttatttaagc cttgtttctg
     3121 agtcagaagc caaagcgtac cgtcagaact tctttcaata cccttcacaa aagtaccctt
     3181 tattgaatat tcatttgaag ggttatcgta tactgtacca aacaaaggca ttgataaaga
     3241 aacataattc agtccttttc cccaagttcc aatccacaaa ttatgaaaac tgtcaatgaa
     3301 taatgtggaa ataaagttag aggaaatgga agtggtatat gcagattgcc gggcatgaat
     3361 atcggcgtaa accttgcctg agtttgtaga aatctgcaac aagcctatat tcgaggcaca
     3421 ccataaagta ttgcttcggt ccacaatcag ttttcctgaa gtatgttgag gaatatgtgc
     3481 attcaagcta tgaaaatcat aaaagtcata acgtgacaag ttcagactgc catctgtatt
     3541 caacgggaat ctggcacaac cggaagatac tctcagatac aggaaattgt ctctaatata
     3601 aagtgaggaa gaagcctcat tccttcggga aatttcacgg catttatatg agttcacaat
     3661 tttcactctg ccctgagtca gcttcacctg taaaagcata tcgggagtac acaaccaagt
     3721 ataatcgcca tttttcacaa tcgtatgcac atttttcttt gccgacaaga cctcagactc
     3781 tttcccataa gaagaaagca agtttctttt acgatccaca ttcaccacat acatggaatc
     3841 agaagttacc acccacaaaa ctccttcttc tgtggcatat actttgtcga ccaaagtgga
     3901 tgataatacc tgaaggtcag cagagagttc aaaatcggca taattcccct gattataatt
     3961 aaatctcaac aaaccgcttt ctgtaccaat ccataaatta caggaatctg tagccaacga
     4021 agtgatacgg tcgtgaagat aacggattct gtccgtcggt ttataatact catacgactg
     4081 caggttgtat ccatcaaaac tttgcaagcc tccattggtt ccaatccaga tgagtccatt
     4141 cacatcctgt gttacacagg ttacatctgt atgtaatagt ccgttctcca ttgtcaacgt
     4201 cctgaactta ggagcatttg cacccataag agtcaggcta aagactagca aacaactaag
     4261 gagtacccct gttttttctt ttaaagacat cataaaatta cattttcaac aaagataaaa
     4321 tatataaatg cattaattac cactcattca caaaaaaaga ggagttaccc cctcttttta
     4381 ctaacctata caacattacc tttatgaaaa ccacgaacaa catccttcat acaagcatgt
     4441 cattcaattg attaaaaccc tattgaaaac ctctccacaa agaaaaaaac aattagttag
     4501 ttgtatttga tttattgtac ggattcttat ttcaaatgta caaatattac ctgaaatcaa
     4561 tcttttcaca atttaagatg gaccatctca gcatctcatg catacttttt tcggtcagca
     4621 cctttccgtt taccctgaaa ttctcaaaaa tgagtccact taaaggagtc tgccccttca
     4681 ctccttccat ataattcttt ttaccttttg aaacatccac ccacacatcc caatccttaa
     4741 acaggaaatt cttaatcaac tggtctttat cgcctaatgg ggataacctg aaaatatgtg
     4801 tcaccggagt atccgtacgc acgtcttcaa atacaaaccc ttcatctgct cctccaccgt
     4861 tccggcagct tagaatacca ttattaggtc tgtccgaatc ccactccgct cgaactatat
     4921 ccacccggct tacacgacag tttcttgcga ctgaattact ccagttcaac tggaaaatgg
     4981 ctccattatc caattgccag catacgacat cttctaccac aatattatct ctatatatct
     5041 tgatattatc atcattggcc cagatgaaac aattccggat tgtagagttg gcataagcag
     5101 caataccgtc acaattataa atccatcctc ccacgatttt agtccaggcc acttcattat
     5161 ccgttcccaa caaccttaca gcaaagaaag aatagtctgc aatcacaata ccatccacta
     5221 taatgccgtc ggctccattt ttggcttcta ccatgtgcga ttcacgcaga tgtaagcgtg
     5281 ctcctgacaa aacccctctt ccgtaaatct tcacattgga acaagccttt ccatccataa
     5341 tgaaagaacc aaatacccaa gctcctcctt ccaggtagat gcgttttata tttgaaggaa
     5401 ctttatacac tcctatgtca tgtacccctt tcttgaaata aagggctgaa tcttttacag
     5461 aaagtgtaga gagaagtgtt ttatcaccct tttctatcac tttccatttt gacaaatcgg
     5521 ccggaacatc cgtttccatc ggatctgcaa aaatcaacaa tccctcctta tagccatctt
     5581 caccaatttc cacagaaaat tgtcctggac ggtcgagcat aaaagagaag cagttagcat
     5641 cctgtttatt cacttttata tcgtgtctgg acggatacac tttaattttt ttcccttcta
     5701 tatctttatt cacccgcact gtaactttca cctttccctg aaacgagaaa tgtccccaat
     5761 gaatgcttct gcctttgaat ttagtcaaag gcttgtcatc gtttttcctt tgtccgggca
     5821 ttcctttaaa ataagtgtta cagacatttt tgaaaatagt cacgtcatta tccgtgtcat
     5881 cattcagata cacacgatac aactcagact gttgtacccg aagatttttt tccggatatg
     5941 tcacaagtgt ggctgttttg tttcctgcgt aaatggaatt catccatgaa atacacaagc
     6001 atacaatgaa taataatact ttcgtcctca tatgtttttc attcttacag cgacaaaatt
     6061 acaagcaaac agactatccg ccttattttc atgtacaaat aatttgtact agcgtacaga
     6121 acccgcagtg tgtacgctgg caacaatttc aaggacacat aaaccagtgg ttagcctgtt
     6181 ccaaggctat ttttgtataa aacatttata cattatgaga aaattcatct ttttattatg
     6241 ttgctgcgta tgtttttccg cttatgcaca aaagtgggaa atgaagcaag ctcctttaat
     6301 gacaccttgg agcaaaaaca tcgacatcca tcatgtactt ccagaatacc ccaggccact
     6361 tatgcaacgg gaagactgga aaaatcttaa tggagtatgg gaatttgaaa tgcgtgaaga
     6421 aggagaccgg ctaccggcaa aaagaaaact tcatgaaaaa atcctcgttc cctatccatg
     6481 ggaatcggct ctctctggag taagaagaca actctctacc caacgggcgt ggtacaaacg
     6541 gacttttact cttcccaaag aatggaaagg caagaatatc attctaaatt ttggagccgt
     6601 tgactgggaa tcagaaatct atgtgaacgg aaaactagtc gggacccaca aaggaggata
     6661 cgatccgttc tctttcaata taacgtctta tcttgactta tcggccaaag agcaggagct
     6721 tattgtcagt gtctatgacc cgggaaacag caaggccatt cctcacggaa agcaaaacaa
     6781 tacacgtttt tccgaaccga aaggctatag ttactcccct tcttccggta tctggcaaac
     6841 cgtatggata gaaccggtca acaaagatca tgtcacagcc atacatacga ttcctgattt
     6901 tgataagaaa gcattccacg tagaagtcaa tgcttccggc aatcagaacc tgaaggtaaa
     6961 catctgtatc cagtcacagg ggaaaacaga aagccaacac tcaggcgcac tgaatactcc
     7021 gattactcta cccctgcaaa ccattcgtcc atggagtccc gacacacctc atctgtatga
     7081 tgtgatagtc aaactgacca acgaaaaagg agaaaccgtg gatagcatca gaagctatgc
     7141 gggtatgcgc aaaatctcat taaagaacga aaacggtgta cagcgtctgg cacttaatga
     7201 caaatttatt ttccagatgg ggccattgga ccagggatac tggcccgacg gcatatacac
     7261 tgcgcccaca gatgaagcct tgaaatggga tgtacagaaa ataaaagaat ggggcttcaa
     7321 tatgatacga aaacacatca aagtggaacc gcagagatgg tactactggt gcgacaaatt
     7381 aggcatattg gtatggcaag acatgcccaa ctgtttcaag acacgaaatg aagaagaaaa
     7441 ggaacagttt gaaaccgaac tgcaacgcat gattcgtacc cactggaacc acccttccat
     7501 tgtcaactgg attgtgttca acgaacattg gggaatatac gattgtgagc gtatcacaga
     7561 aaatgtcatg aagcttgacc cgagcagact tgtcacaggc aatagtggta tcgatgcccg
     7621 gaagcccagt atcgactatg aagtgggcca cattaaggac aaccattcct accggcctcc
     7681 tcacgtgccg cttatcagta gcaaaagagc caccgtcaac ggagaatacg gtgccatcgg
     7741 ttataaaatc gaaggccata tctgggatac cgacggacct tgggtacacc acaactataa
     7801 gaacaaggag aatgcgacaa aagaatacgt aaaattcatt cagcaaatca acgaatacat
     7861 acgtcgcgga ctcagtgcag ctgtatatac ccagtggact gatgtggaaa atgaaatgaa
     7921 cggactctat acctacgacc gtaaagtaga gaaattagat aaacaaaaag tatctgacgc
     7981 caaccgctcg acctatacag agaaagagca gataaaaggc cagaccgatg cacaatacat
     8041 tcaataatct tttaattaca ccttatgaac tctattaaac tgatttcact tgccgcactg
     8101 gcaacttcac tcatgccctc ctgggctgct caaaagcaaa acaagccgaa cattatcttt
     8161 gtcatatccg atgaccatag cgttccgttc ttagggtgct atggaaataa agacatcaag
     8221 actcccaact tcgataagtt cgcttccgaa ggaatgactt ttaccagaac ctacgtgacg
     8281 gcccctcaaa gtgctccttc acgttcttct ttcttcacag gacgttctac catctctact
     8341 acgatgtcta tgttctctct gcctctgcca ggaaatgtca ttacctatcc tgatattctg
     8401 aaagagcatg gatattacat cggagtgact gcccgaagcc atcaccagga tgggctgaaa
     8461 cgcaacaaag acattcagca ggccattgaa agaaacgaca tggctacctt cggtcgtcgg
     8521 ttcgattatc acagaattgg cggacagccg ttgccggaac tgaaagtctt tctggacaag
     8581 gctgccacag aaggaaaagg aaagcccttc tatgttcagg tcagtttcta cgaccctcat
     8641 cgcccatggg ataagaatgc tatcccagaa cctcatgacc ctaataccat taatttgcca
     8701 gacaattatc cggataacgc acttattcgg gaagattttg cacgtcatta cgatgagata
     8761 gcccgtatgg atacccagtt cggactcatg atggaagaac tggagaaacg aggattggca
     8821 gacaatacta tcgttgtatt tgtaggcgat aacggttcag ccctgttaag aggtaaagga
     8881 accctttatg aaaccggtat caatgtacca cttatcgtac gctggccagg aaaaatcaaa
     8941 ccgggaagct acagtaatgt acttgtatcg ggagaagact ttgctcctac cctcttggaa
     9001 ctagcaggat ataaagccga ccctaaaatg accggccaca gcttcgctca taccctgttg
     9061 ggtaaagcag gaaccgacag aacgtgggta ttctctgccc gtggagctca cgcagaagac
     9121 ctgccagtca ccaccaaaga ctttgacctc atcagagcca tagtgaccga cagatacaag
     9181 cttatctata acccggtgag agaacttccc tactggccgg tagatttctc acatgaacca
     9241 ttctggctcg acctggtaga acaaaacaga accggcttca taccacggga atggaaagaa
     9301 agatatttct cagaaagacc gatgttcgaa ctgtatgacc tcaaaaacga cccgcaagaa
     9361 ttacacaacc ttgcaggact taaggaatat gcagaaatag aaaagaaact gcgtgacacc
     9421 atggccgaga aaatgctggt agaccgtgat tatgtgccac ttcctttcta ctcactggac
     9481 aaagaatata aatagaacgt acaaattcaa taagaatgcg gacacaggaa ccaaccgttt
     9541 tctcttagtc cgcctaactt tgtgacaata accaaataat tataaatcat gaaaaataaa
     9601 acattcttat ctgccgcact ggctttcttc atgctggccg gctttaacca gacgactcag
     9661 gctattactc cgcagatgcc gtctgaagaa acagtaagca aatgcaaggt ggctcccact
     9721 cctcctatgg gatggaacag tttcgatgca tacgactgcc gtatcaacga acaggaattc
     9781 aaagccatcg tagactatat ggctgccaac ctgaaacagc atggttggga atatgccgtt
     9841 atcgattact gctggtttaa cgataaccct ggaggttgga ataaccccag caaacgatat
     9901 ggccatccgg acatccgatt ggataaagac ggcaaaccac tcgacgtact ttgcatggac
     9961 gaatacagtc gtctgattcc ttctgtgaaa agattcccgt ctgcagcaaa cggaaaagga
    10021 ttcaaaccgc tggccgacta tgtacacagc aagggtatga aattcggtat ccacatcatg
    10081 cgtggtatag ctcgccaggc ttacttccag aaatcaaaaa tcatgggaag caaggctacg
    10141 gcgtacgaca tagctgaacc tttcgacaca tgtaactggt gtaacaacat gtacggagtg
    10201 gacgcttcta aagaaggcgc acaggaatac tataactcta tcttcaaatt gtatgcagaa
    10261 tggggagtag actttattaa agccgacgac accatgtatc ctccctatca caaaggagaa
    10321 atcgaaatga tgcgcaaagc cattgaaaac tgcggtcgcc cgatggtact gagtttatct
    10381 tgtggtgaag ctccattagg ccgtgcagaa cacattaaga agaatgctac catgtggaga
    10441 gtttcagctg atttctggga caattgggaa gatttgtatc acaattttga cttactgaat
    10501 gcctggtctt ctcatatcgg cgaagacagt tggccggatg cggatatgat tccgtttgga
    10561 aaactggcac ttcaaaaccg tccggtagga aaagaacgca tgagccgttt cactccagag
    10621 gaatataata cgctcatgac tctgttctgt atggctcgct ctccactgat gattggagcc
    10681 gacttgcttt ctacccccaa agaaatcatc gacaaatatt tcaagaacga tgaaatcctt
    10741 gccatcgacc agcactccac agataaccgg caggtattca agaacaagag ttatgccatc
    10801 tggactgcta ctgttcccga aacaggcgaa cgctatattg cgctgttcaa tctgcaagac
    10861 aaacctgcta ccgtcacttt caatatggaa ctggaatctc tacgcggaaa atatcaagca
    10921 cgtgatttgt ggaagaagca gaatatcggt attgtggaag gaaaactttc tgctcagttg
    10981 ggagcacacg atgccactgt attcaaactc acaaaagtaa aataatccag aaagtaatct
    11041 caatgaaaaa aatcaatatt ctacttattg gtatattcat tacttttcac acgctatacg
    11101 cccagacccc tctttggcag gggaaagggc gtattgccat aagtagcgac ggtaatgaac
    11161 acgatgatga tgactgggct gccactccgt tgtcgctcgc tatgattgca gctaaaggcc
    11221 tgcaagacaa gcttgtattg tatacctaca gcgaccatat ctgggggagc aatcaggatc
    11281 gccctaacaa acatggcatt agtgcctatg agcacatgcg tctcagtgca ctgggaagca
    11341 agaaatggtt tggctttcac aatagccgtt tcatttgtgc cgtagacaat gctgaaattg
    11401 cttacaatgc catgagagac gtaatcaatg cttcctccgc agaagatccg ttaatcatcg
    11461 tagctgccgg acctatgcaa gtggtaggag aagctcttca acgctccgat aaagaaaagc
    11521 gccaatacgt taccctgttg tcccactctc aatggaacaa tcgtcacagc gacaatccgg
    11581 aaagaaaaaa aggatgggat atgcattctg gctggacatg ggacgaaatg aaagctgcat
    11641 tcggtactcc ggaaggaggt aatgtccgat tcgtacaaat tctcgaccaa aatcatggaa
    11701 aagattatat cggtttcttc tgtcccaaag aaaactacga ctggataaaa acttcaccag
    11761 ccagaaattc tcccgcctac caaccaggag catgggactt cctgtatgaa cggatttcca
    11821 cttgtatcaa gaaaaaagga acttgtttcg acccctcgga tgcgggcatg attgtatacc
    11881 tgttcaccgg aatcgaaaaa actaatccgg acatggcacg acaaatcatg gagaatcctc
    11941 aattcaccta tcaaaaccca attcgttcag gtatagaccc caaaggatta agagactgcc
    12001 aggtactgaa agaccagaat acctggtacc tcacaggtac cgcttttccc cattgggcac
    12061 gacaggaaca aaatgggaag ctgaaccaag gagttcctct ctacaaatcc acaaatctga
    12121 ccgactggac tttcgtaaaa tacatcgtag aaaggcccga ttccagcaaa tggtattata
    12181 accgtttctg ggctcctgag attcataaaa tcaaggggaa atattacgct accttcaact
    12241 gttccaaccc caagcatggg tatcccggac aacacatcgg ttatgccgta gccaatagta
    12301 ttgaaggccc ctacaaggtg attacagaag aaaagccact ggccaatgga aacgacttga
    12361 cactgttcga agatgaagac ggaaaagtat gggcattctg gaacagagga cgtgaattcg
    12421 gtattggata tgcgcaactg gatttagaaa ccggaaaatt tctgactacc cttcagacgg
    12481 ctatccagcc cgggaaggta gattatgaat acgataagga aggaaaatta gtacacgaac
    12541 ccggatacga cggacgcccc atccccaaag taaagaagta ttactcctgg gattccatcg
    12601 gtatagaagg ggcttacgtc atcaaagaaa acggacaata ctaccttttt tattccagtt
    12661 ggaccagagg atatgaaatc ggctatgcta ctgcttctaa aattaccgga ccatggaaga
    12721 agtatgaagg aaatcccttc tacggagcac aaagcaaagc cgcatgcaac agaaacggat
    12781 tcacctggaa aggtgaccca tatagtccgt tcaaccaagt gggccacaat gaaatatttg
    12841 tcggaccaga tggtagatat tggatttcct gccacggaat tacacacgac gctcccgaaa
    12901 gtccctcatt ggttattgac ccgatatggt tcgaccacga cgggaacatc aagagtaacg
    12961 gtccgacata tactcttcaa caaacaaatt atttgaacaa cccaacctct aaggctaaat
    13021 aactcatagt caattcatcc ctcggtgctt gtgaaagtat cgggggaata taatttctac
    13081 tgaataagat ttgaagacat aaaaacactt ttaattctaa aaaacattta taatgaaaac
    13141 gaagtttatg ttatccacgt tgctggcttt tcctgcgtta agtcatgcac aaaccaactt
    13201 tatcatcatc cttaccgatg accaagggta tcaggacata ggatgctatg gttcgccact
    13261 gattgaaact cccaaccttg acaaaatggc ggaagaagga cttcggctta ccaattttta
    13321 cgtatccgct tctgtatcga gtgcctcgag agccggactg cttaccgggc agttaaacac
    13381 acgcaatgga gtgaaaggtg tgggctggcc agattcaaaa ggacttccaa cagataaaat
    13441 cacgatagcc aacgcactaa agacaaaagg gtatgccacc ggatgctttg gtaaatggca
    13501 cttaggcgac cttgacggat atcttcctac cgatcgtgga tttgattatt attatggtat
    13561 cccttatagc aacgacatgt atatagggta cacacataaa ttctctccca actgtgtgtt
    13621 taccgaaggg tataatcttg ataaagcctt acaagaccag caactggtaa aaagaactaa
    13681 aaacaaagcc caactgaaaa aagaactgaa ctatgcttcc cctttgttcg aaaacaagga
    13741 agtcatagaa tatccatgcg accaagctac taccacatac agatatttca ataaagcaat
    13801 ggaatttatc gggaaaaaca agaaccagcc gttttttgta tacctgactc cttccatgcc
    13861 tcatgtgccg ctttttgtct ccccacagtt caaaggaaaa agtaaaagag gattgtatgg
    13921 agatgccgta gaagaaatag actggaacgt aggccgactg cttgatttct tagaaaaaga
    13981 agggctcagc gagaatacaa tggtcatttt cacttccgac aatggcccat ggttaggaat
    14041 gaaagaaaac ggtggatctg ctcttccatt gagagacggt aaattctcgg catacgaagg
    14101 tggtgtccgc actccttgta tcatcaaatg gaagaaccac atcccggcag gaaaagtgag
    14161 cgaccatatc attgcaagta tcgatatctt ccccactcta ttggaacttg cccagatgga
    14221 caaatcaaaa tatgatcttg acggtatcac acttaccaag ttcataagca atccagataa
    14281 tgtagagcct cgcgaccgct atttgtatgt caaagacgga aagattgtag gcatcagaca
    14341 aaatgactgg atatacctgc cgcaaacagg actcagagtc actcccaaag gaaactttga
    14401 gcaagaactc ttcaatatcc gtatggacat tgggcaaaaa tcaaatctgt tcaaaaaaga
    14461 aaccaagaaa gctcaggaaa tggaacagct attacagcaa caatctcatt agtccctttt
    14521 gagcaggtgt atattaaaaa gtctggtatg aaccacagca ggttacatac cagacttttt
    14581 ttacaggatc tatctataac agacaagcag gttatttgta catcacaaac tgattcttgc
    14641 cagaatctgg agttaccaga taaaatccgt tgtcaagctt cttgtaactg gcatactgac
    14701 atttcagaag cggcttgtca ctatatatca caaaaggtgc attctccttc aaggatactg
    14761 tcaacttatt cttttcagcc ttatacttct ttactgccac cggactgagg tacttgttct
    14821 ccagccctat aaccgaccag ccgttctcga tttcacacag caacaccaga cggtcctcca
    14881 tattcttcag gttaaacgca tacttatctt tcagcacgtt tcctttcttc gtataccagt
    14941 cataatatac cagtccctct gccggaagtt cacgtcgtcc cggatacggc tgtaccatcg
    15001 catccgcata tgtatagtct tctgcagtaa cctctacctc cgttatattc ttggtatttt
    15061 tgtttgacag gctataagcc accactgcag cagatgtttc agtcaaagga gctatcacat
    15121 aatacacccc atctcctgtc agcacattgt taaacagaga cttgggcaaa gaagttcccg
    15181 gagccatagg acgcaagatt tcaccgtctg aaaaagctaa tggagaaata taatcatcca
    15241 caaaattctt gggagggtca gacagataga taggagccgc cgacatcgct ttgctgaccg
    15301 ccatcagacg ccccagtctg gcatctgaag aatgaaacat gtcatgatcc ggccaaaccg
    15361 tctgccccat ccataatgtg ttctggaatc cctgatagat atgatttctc gccaatggaa
    15421 tgctgttcaa cttataatcc acgctcacac gcgtcgttgc actgtatttg gtattaaatg
    15481 cacaaggcag gttctgagcc atacagttca tcaatccatc cagtttcttt ttggcatacc
    15541 gctccagtgc tgccgcattg ttgtgatgcg cctccaccgg attggatatc atcagatagt
    15601 tgttaaagtc acgtgtctga acgtctattt taatgaagtc aaaatcattg tccgatgcag
    15661 aagaaaccat cttgttataa aacaaatcgg cagcttccgg cgaaccgttt atgatgatac
    15721 gtcctctgtc attcttcatc agataaggct ttaaatcatc cattttatga ttggccgata
    15781 taccacccca tattccatac atgcaatgcc acaatccgaa ccactttatc ttgtccgaac
    15841 gtttagataa caaaggagac catcctcttg ggaatttctc tggactcacc tcaaaattga
    15901 taagtttgtc tttcacctga gtctggtgtc catgatccac cagaacccag cgaatgggta
    15961 catcagattt ttctatccca tccacagcct ccagcaacac tttttcattg atgtttttcc
    16021 ggaaatgctc ccacgaacac caacctaaat atttgaacgg ctccggataa accttgtcct
    16081 ttcttaattt cagattatct gctatgtatt tatcctttac caaagaactc cagattgcat
    16141 tcactacctt atatacatcc ccacttcttc cataggcaaa caccggagca tctttcaaat
    16201 ccacttcttc cgttcccatg gtaccgtatt taatatcaat gtgattatcg tccaccactt
    16261 ctatccagct catagctgaa ttaatggcta ccggctgcac tacccagtaa cttccatcct
    16321 gaagttccag gacaagaaag ataccacaat tgacaggctt atcaatagtg ggtaccggtt
    16381 caaatgatgc atcaaaaagt gcagacaatc tatccacggg ccatgaaaaa ttttggttta
    16441 tcccgtcaaa acccttaaac cgggaagcat agaacaatgc cttcttatac acaggcaatt
    16501 ctatacgata actctccaac actccctcta caggctttcc ctttacagaa gttctaaaca
    16561 cagcgcacga atctgaaaaa gacagattca agtcttttgc cttcgacgga ataccttgta
    16621 tccacatcaa acacatcaaa acaaaaaacg ttacatactt tttactcata atacaatgta
    16681 tatttgttat tttatgatta taccttctgt cgtattttca ttagtcagca aattcgcgtc
    16741 agacatattc ttccacaatt tgccattcac cttaatattt tccagaagta cattgcttac
    16801 cttatgaata gaatcgtgcc ccataatgat atttctcatt tcaggttcgg tatagcactc
    16861 aatatttctg aaggtaagat ttctgatttc acctctttcc ggatcccagc ttccgaaacg
    16921 gttaggtttt gtcatgatat gaaacaaacg atgcttgcag ttatcaatcc gaatatcctc
    16981 atacaaataa ttggtcataa tgccattact gccatgaatc gcatcaaata cagcttcatt
    17041 aggattgtcc caaggatgct ccacccggat tatatccacg tcatagacat gaaaattagt
    17101 gttatacccc ggcatattcc agccaatctg aaaaggagcc ccgttttcca tctgccatat
    17161 cacgcatctt cttgctatcg tgttgcttcg atacaacttg atagcatcat catttacctt
    17221 gaaaaaacag tcttctatca aactattgct tccaattcct attccatccg tactgaacca
    17281 ccagcccatc atcttcaggt tccggcatat ctgattagta ccagttaacg acacacaaaa
    17341 cctcggtgca ttgataatag tcaccccttc aatcagtaca ttattacagt tcctaaaagc
    17401 aatcatgtga ttatgactcc gtgcaggata ttcttcccca cttataatac cctgccccat
    17461 aatggtaatg ttctcctgcc cgtcagaaac gaattgtcct tttacatagg cgccaggagc
    17521 aagatatacc gtttgattgc tcttcaacat gtagttgtct cctatctcgt gtatcccttt
    17581 ttcgaaaaca atcagattag gagtatgctc agctggtttc ttgagagggt acgtatccac
    17641 aaaaatcagc aagggatggg caatagccac tccctcctcg aattccactg aatactgtcc
    17701 aggaccaggt aatttaaatt ctacagtcga atcattcaaa atgtgacatg cgatattgta
    17761 cttacgaggc aatatccggc atacttcaac cttataagca ttagtcttta ccctgacaac
    17821 aggtttcgta tctgtagcaa aagatgtcca cgaagttgtc ttacaccggt tagttttcca
    17881 ttgtgccaca ttggtataca caggagactc caaaaattct cctccatccg atacctcaat
    17941 ttcaaataaa gaagatttct tgataccgtc ggccatcgga tatacaaaca ccttagccaa
    18001 aaccacatca gaacacaatg tggcaaagca taatatcatt aacaacaatc tttgtttcat
    18061 gtttgataag tttgaaaaag ttatttacgg aagagttatc acacacttaa atccattctc
    18121 atccgggtac acacggtcaa cgcaaaaaaa cggttccgca tatttatcct cactatgata
    18181 cgagatatac cacttgtcat tcagtccctt aaacaattgc acattgccta taatctcaca
    18241 aggaggagca aagacaagcg ggttgtcata ttcaccatgc aactgagtag gagcctgatc
    18301 ttccgaacga taaaacagaa tttcatcaga agctttccaa ggaccaagcg gagattcaga
    18361 cactaagttc gcagcatagt atcccccttt aaacaccgta tagaagagat aaatcttacc
    18421 tttgtatttt aagacggaag gagaatccag aaaacggtca tcttttctaa actgacgagg
    18481 tatggagatt accacaggat ctccggcaag atgtgtaagc gcagtatcca tcaatgcacc
    18541 acacagactt ccgtctttct cccaataagc atacactttt ccatctttat catcctgcca
    18601 taaggtaaac ctgtttcctt tgacaatagg tttatctgtc acaattttat aaggcccttg
    18661 aatcttatca cttatggcta caaccgtttc cgtagtgcca taaggattta cgtcgttgtt
    18721 cctgcctccg aaacacaaca catacctgcc gtttatctta tgaatttccg gagaatcaaa
    18781 accattttta taccatgaat cggcaggtat actttcccgg tcaactaata gagcggtttt
    18841 cttccatttc ttcatatcct tactttcata caaagatatg ccttctttat tttcacccgg
    18901 aggagctatt tccgtcccca ccatatagta ccggcctttt tctacataaa catgacaatc
    18961 tctgattcca tattccggca aacctttacg tatcggattt cctgctaacg cactctccaa
    19021 acaaagacat actaacagga acagaaaaat ctgcttgtta aacagacatt taaatgacgc
    19081 gagattcata atctaaattt taaatcagct ttaatataca gatgctctac aaacctatca
    19141 ctccgccttc ttccattccg taagcaaccg gaagaagcct ttttttcttt cactgttgat
    19201 gccccagtcc gcaggaatac attgaaaacc ctgttcgtag ggttcatcct ttttcctgaa
    19261 atcaaaatat ccccacgaag cataagcctc tgtagctttt acaaaattat tgacctcttt
    19321 gtcaaacttg aagtggtcat cctcgttgta aaccatgggc ttgggagtat aggccggcga
    19381 ttttctcacc gaatctacct gcagggttat tctttcaggt ttccataccc cgtttccatg
    19441 aagcaagaca aaatcggata cagcaatgac tttgtcactc ggaacaattt ttccggcata
    19501 actggtgctt accaacaaac gtcttccatg ataagtaatc gactttgcat attcaataga
    19561 ctcatgcaca gtttccggac tcaacccatc caacttgaag aaatcacact cattgttaat
    19621 ctcaagcaac acgttcttat atccgttcgt cagtacccac tccactgcat tctttattcc
    19681 atttctggca gcctctgcat tgtccaggaa tttttcctga cctacataaa acaatcccaa
    19741 tatcaccacc atttccagct catctgcttt atcaagaatc agcttcagtc gcttcatgta
    19801 ttcttcatcc agacttccat ccgaaagaat agctgaatta tgccagggct gtgtttccga
    19861 gtatccttcc ggacttcccc cctgcaggtt aatggtaaaa gcaagcagtc ctttttccct
    19921 ccataccggc atattctcta caaactctct tgtattgcgg ttggcatccc atactttcgt
    19981 atccggatac gcccatttat aacgcgtaga atccgtcttg tcatcaaaat tccattcaca
    20041 agtcgcgcat taggaagcaa tccttgtatt ttcatccccc tccaggtttt accttcgaac
    20101 gtaggttttc cgttaatata gaactcttca cctacaatcg aaacttcagt tttgtgaaca
    20161 tcagcagttc cacaagagac gaacaacaaa gaaagaaatg ctgtagaaat aaaactttgc
    20221 ttaaaaaaat gcttcatatc atccactatt tatcttatat taaactctaa attttattgt
    20281 ttctttaaac tccaggtctg ttcaaaaaca aaagattcac ccggcgacaa cttatacaaa
    20341 ggacttacag gctcaatctc acacaacttt ccattggtat aaaatatagt tgtatacccc
    20401 atagtagaag aataatccat ctgtggcatt actttgaaag taacctcaaa ctttaaatct
    20461 ttatacagat aagaaatccg cccagaccta ctattacatc ctaacttcaa ggtctcatct
    20521 gacacgttgt aacacaattt cccattattt gtcagcacct tatcactttg atagtttccc
    20581 atatatcccc atacctcatt atctgacaac gggagtacca cacgtccacc tcctttgcag
    20641 aaataccttc cccagaaatg acggttcaga catttgtctg tatagttacg ggcactttgc
    20701 ctgatataca gttctgagga atgtgcatca agagtaaaag tccgtttcaa atgaagtccc
    20761 aacctattat cttttgagaa cgaaagttca accgtatatt catttattat tttataatcc
    20821 cataccccca taaaaggctc atcacgtaac ttgccaggaa tggcttccgg tcctatgtca
    20881 aaccttgccc catccggcca atgcctgtct tttctgaaat tttccaacag ataaccatca
    20941 aactctctgt cttcaaataa aatattctca ttctctactg aataacataa tacccttccg
    21001 cccgattgtg gagatataac aacccgcgta ccggcattgc taatctcgat acagtttgac
    21061 catcctctgt actcattcaa cacaacaact ttagaactta ggcttgcaac ataagccaca
    21121 aacaataaaa acaggagtat ctttttttga ttcataaata tttatatcgc aaataatcag
    21181 tttattaatt tatcatatta accgtcaccc tttttcagga acctaaaatg ctattatatt
    21241 atttaaaagt ttcacgcaca caggattatc aacggctttc ataaaatcaa gagaagaaat
    21301 gataatatgt cctttaccta ccggcaatat ggtcaaagca ctaaacaact catttttatg
    21361 gtctgcatag cagcctacca cacattcccc gttctcaaga cgaagtcctt ccctatgccg
    21421 gttgtacgaa gcaaaacact ggtactccca gttgaaagct gtagcttgcg gcaagccatt
    21481 aaacaacgca tggtttttca caaagaaatt tcctccaaac cagtctcttc caataagtct
    21541 tgatcctctg tagtctgcca cctctttttg ttccagataa gtacaccatt ccgatgcatt
    21601 atcaagtatt acaagctttc ctccgcgaga aacccattct atcaaaggat cgtcttgtct
    21661 gaagttacca ccaactatac caggctgtag tttacctcca accaccagtg ttcccattcg
    21721 ggaaatgata tctttaattt taatattctg atagggaata tgagctttct gaagcactcg
    21781 ttccatccgg cccgcagtgt cggccacgta cacggaagga tgagcaaccg gcgaattgtt
    21841 cacggcaaaa acctgttcgg ctccttgagc cacaatctta ccatgctttg acagttctgc
    21901 ccttatagtg gtatagccat cctggttgat tttaaatcga atgtgctgtt tcagaagctg
    21961 cccgaaaata acgcctcctt tcactgctac ctgaaattcc tgcttctgcg tccaggcatc
    22021 attagcctga tttcccagaa agacagtcag cttgtaccta cctttcaaat ctttcctgtt
    22081 caccacaaag aaatctacgc ttgtcgtatc attctgttcc agcacctttt tattagcctt
    22141 tacagccaca taaagcggct gattataata tgcgataatg gcaggatctg ctttatggtt
    22201 tctatatata tccacaatcc cggaatgatt ctccagcttc gtactctccc aaccgtttgt
    22261 agcccagcca tcgatattgt tactgatata catattctct atcatcctgc cttgataata
    22321 atatgacaca ctaccaagac tgcggcataa agaatctaca tcgggaaaag catccgtaaa
    22381 ccctttttca tggataaacg catcaaaagc atgatattgc ttcaacaaat catcaccagt
    22441 ccagcctctt ttccctcctt tttcaatttc ctgctttatc agttgaagac gaggtggagt
    22501 acctatggct ccttcttctc cataaaatat gatttcatcc ttttctttct tatatcttga
    22561 aaaatcaaca ggcgatttat aaaactcatc tttatacact ccaggcccac tggcatgatg
    22621 ctggtcccac cagccttgat aatgaatcgt tgtatcatta ggcaacatgt gcatttttat
    22681 tggagcagga gtcgacggac aaactccttt gtaaagcttg gctccgaaat aggtagacgt
    22741 aaatgtaata catctggtag gatctagcag atgtgcttcc cgaatgtctt ctacctcatt
    22801 aggatatgga tttcgggacg attcattaat catattgaca atcacaagcg aaggatgatt
    22861 tcggtctctt ttcaccatgc gcaaaagctt ctctcttttc cattttctgg caaaagcaga
    22921 atttccaggt ctgtatcctc ccggttcttc atagataagc ataccaagtt catcggccag
    22981 atcaaaaaca caagattgtc cgataccccg atggaaattc agcatattca tacctagctg
    23041 tttggcagac atgatatgct ttcgggccag ttccgtagta ggataaattc cattaaccgg
    23101 ccaatgcccc catgaaatag ccgtatgcag tactatacgt ttgccattca gcataaacat
    23161 cctgtcgcca ttaactgttt tcacatcaaa ccaccggaaa ccaaaccgct ccgtttttac
    23221 atgcttctca cccttatcat tcatccattt tgctgtaagc acatataaat tcggactatc
    23281 cggactccat aattttgcat ttttcacctc tatgtttttt tctacacaag ccttctttga
    23341 ccaagaggga accactgtct ttcctttcca gaccagtttg tccgttccat attcctttat
    23401 ggaatattca atgactccgt tacataaatc tccttcattc tcaagagtag tcattacgct
    23461 tacccggttc aaatcgggtg tgttttttat aaagatatcg tctatatagc tgtgacttgt
    23521 agcatgaaga cttacttttc ccgtaattcc accaaagcca tgacttggag gtatttcata
    23581 ctttccccac ataaaagaat cccagtctct ccacgcaaaa ttaccattag ggtcagttat
    23641 tcttacggcc aatctattgt gcgaacctat ctttacgtca tcagtaacgt cgatactgaa
    23701 aggcgttcca tttatcagtt cataccccac cagcttgtca ttaagataaa cctctgccct
    23761 cattctggca ctttcaaagt ctatcgtaat acgtttaccc ttccagtcag caggaaccga
    23821 taccccggta gtaaaccatg aaacaccaca ataattccca ttaatcccat atgtatttcc
    23881 attctttccc cacatatatt cttcaactgt agcaggtatg gtaatatcta ctgcattttt
    23941 attattgtaa agattctgcc atccacaagt gggaggtgta catggaatca catccatatt
    24001 atatgggggc aaatagagcg aatcattaaa atattccgcg gtttcatcaa gccatagccg
    24061 ccacggctgt ttacttaaat caattgtttg cgaactggca tataatgata aagtcagtaa
    24121 agcaaaaaga agaacgtctt ttttcataga tccaatcaag cattaataca taatatacct
    24181 acttccatat agtatttaag gtccggtaaa aatttgctat taccggacct tatcctaaat
    24241 cctatttatt ccatatctgg catttattga taatatggat gctgctctat ctgaggagca
    24301 gttttcaagt aatttgcagg caatggaaat acagttctgt atttttctgt ccgaatctta
    24361 cttctatcca tgtgtatatc atccacccag tccatatctg taaatttctc gaacctgatc
    24421 aaatccgttc ttcgtaacgc ctcaccataa aattcccttc ttctttcttc tagtaaggca
    24481 tccattgtca gattagatgt atcataaaaa tcatatcgtg aagggtcaga aatggatcgg
    24541 ttgcatactt cattcaccaa gtcaacagct tcctgtgtag cctgtccatc tgcgagtctc
    24601 attaaacact cagctttcat catcatgata tctgccagac gaacaaccac aaaatcattg
    24661 ttcatggcat ctgtaataat accgttctcg tattcatact tttggaatct ggctccactc
    24721 atttcatcac agttgttaat atcgaaatcc accttaaaat ccaaatccat gaacgtgccg
    24781 tcaggatttt tcatttgtgc cttgatacat ttcaacggtt taccagaagc atcaaactga
    24841 gggccggcat tcagtccgtt ctttcttaca tcaaagtctt caaatgtttt atagagtgaa
    24901 ggatatacag aaaagccatt ctgtccgtta accgtaccat tgtatacagg cgtctgactt
    24961 gcatgcaagc aatgacgggc ataaccgaaa cctaatgtaa agttatcctt tgaatacacg
    25021 gcatcgaaag gaataacaaa aatattttcc ttggaatttt cattatgggc tttaaagtta
    25081 gtaaagtagt ctttttccaa ttcaaatcca gcctcaggcg acataagttc atcacagata
    25141 tctatacatt catccagacc tgttttttca tctgcatact taggattaac cctgtccgtt
    25201 tcaagaaata tctttgcgtt cagcagatac ttagccttta atgccaaagc tgcccaataa
    25261 ttgaatttgc cgtaagtagt cgatttatcc ttcttggctt ctttaagcaa gggcaaacaa
    25321 tcgtcaaatt ctttcatcat gagattgtat atctctgccg atgttttctt cttgatatct
    25381 gaagtcttgt cagaagaaga tactgtgtaa ggcacatccc cccataagtc tatcagcaaa
    25441 taataagcat acgctctagc catccttatt tcagcgatag taacatcctt caggtgctgc
    25501 tccattccgt caaagctgtt cacctgatca atggccatat tggcactggt gataatacca
    25561 aaacatttct cccagttttt atcaaggtct tgtgtagttg gagtccagct atgctgatat
    25621 gcatcagaga attttgcatt attccattcc tttgtaacgt ttctaaaagg aataaacatc
    25681 tcgtccgtcg tacatacatt atagtagaac ggtgaaaaat taggattggt agcagcaatg
    25741 tatgtaccaa tgcttgtata cacttttcca attaaaagat tgatggaact gggattttta
    25801 gaaaaagact cttccgtaat ctcactatac accgtatcag aaaggtcggt acatgctccg
    25861 caagtcagca aggaagcaaa cataaatgcc tgaactattt tattatgtga tttcataatc
    25921 gtcttcatta taagttagaa agaaattttt acgcccaaag aataagtacg tgccaccgga
    25981 taagcatcca tattgtctac acctaccact gtgccattaa tctccagctc cggattttga
    26041 cctgaatagc tggtaaaagt ggccacattc tgcacactgc catacaagcg caatgaagaa
    26101 ataaacttat tattctttat cgggaaatta tatcctaaag taatgttgtc aagttttaca
    26161 aagttaccat tctctaccac cgcgtctgta atagaaggct catcataaat aggcgatgta
    26221 agagctgatt tcagaacatt gtctacacga ttgaatgtag gacttccctg atatgcacta
    26281 cctaaattca ggatatcaaa tccaaataca cctctcagca agaatgaaaa atcaaaattc
    26341 ttgtatctga actgatgact catgtttgca taatatttgg gcataccatt acctatgata
    26401 gttttattat cctcactacc tttggcatcg agccaacgaa gagtcaaagg ttttccatct
    26461 tctcccattg caatcgactt gtcctcatta agctggtaaa ccattgtctc gccattttca
    26521 ttgacacctg catacttgaa tccccagaag tttccaatcg gagcatccac cttagtcact
    26581 acagcccaat gtccgttcat aggtgaagcc agattcaatt catatctttc ctgaacatcg
    26641 ccgtctgcag tagtcagttt ttccacattg tttttattat agctgccatt aaaattcatg
    26701 ctccatgaaa aattcttttt ctgtataagt gtggcattaa taccgatttc aacaccctta
    26761 ttcgaaatag taccgatatt accccacatc tcagatgcca gatacggagg tacaggaaca
    26821 ttgtatttat aaagcaaatc ttccgatttc cgctgataaa tatcaatatt cgcattcaag
    26881 cgtcctccta aaaatgccat gtcaagtcct acatttaatt ctttctttgt ttcccatttc
    26941 aaatctggat tcgcatttgt tttaggagca taagtaggct cgtaagcatt gccactggta
    27001 gaaccgttat gtgcataaat aggctggctg gcaaacaaca cgtagttaag ataagcctgg
    27061 tcaatcatat taccagttac tccatagccc agtcgaagtt tcaaatcact gaatactttc
    27121 tgctctttca tgaacggctc attgataatt ctccacgcca cagaagcagc cgggaatgta
    27181 ccccactggt ggttcttgcc aaatcttgaa gaaccttcat gacgtaccgt agcattaaac
    27241 aaatatttat ctttgtagtt gaacacaact ctaccaaaga aagctattaa tttagatgaa
    27301 cctttatagc tgtcaaggct ggcctgtccg ttctttaatg cggcaccact accaatggag
    27361 ttatatccgt tgtcatcaaa cttaaaatca tagtttgtcg catcaagata ttcgttaatg
    27421 aattcctgat agctataacc tcccataata tcaaaattca aatcatctat caactgtctg
    27481 ttatatccgg cagtcagttc taaagtacgg gtttcattaa gagccgattt cttgtaagcc
    27541 tccccacttt tacctttcat catcatttcc tcatgttttg aggttttata ccatgccaag
    27601 ctagattctg ttctgtcaag tccaatcatt ccggtcagag tcattccctt gaaaggagtg
    27661 attgttatct tggcatttcc cataagcgtg ttatatttat cttcacggcg agtttcattg
    27721 attagattca ccggattgtt atatatcaat ggatcggctc ccggagtata gcttccgtct
    27781 tcctgataag gagtcatagt cggattccag aacaatgcct ggcgaagagc cagcttctca
    27841 ataggaacct gagtctttga agtataagcc aaattcaaat ttactttcag gttatcattg
    27901 aagtgcttga actcagtaga gatacggcca ttgatttctt ctttaccaga agtagccact
    27961 ataccctgat aattattata tgtcaatgag gctgctgttc tggaatgttt tgaactggta
    28021 ttcaatgaca gataatgctg atggctgaca gctgtacggg taatttcctt catccagtcg
    28081 gtattacccc cataatctac catggcttgt cccttctcct gagccaactt tatactgctg
    28141 ttcatcatag attctttcaa ggagcggtac tcatcgcccg aaagaaggtc ccaagtgctg
    28201 cttacctgat caaaagacac atttccatca tactctattt tggttttgcc atcggccaca
    28261 cctttttttg tcgttatgat gataactccc gaagttcccc tagaaccata aatggctgcc
    28321 gcagaaccat cgcgcaacac atcgatagat tcaatatcat taggagaaac agtagacata
    28381 cttccaccag gaatgccatc aattacgata agaggagaag ctcccgcatt aattgtactc
    28441 atacctcgaa tctgcaaagt catatccgat gtgggatcac cacctccagc ccgcgacatt
    28501 gctagtcccg gaattttacc ttgcaccatc tgaagcggag aagaagaagt gacggtctga
    28561 gtaaaatttt ccttcttaat agaagccacc gcactggtta catctgtttt tcgctgtaca
    28621 ccgtaaccta cgacaaccac ttcatccaac acctctgtgt cttcctgaag aacgatatca
    28681 attacactac ggccattaat ttccagtttc tgggtctgat accctacata agaaacgacc
    28741 agcacattct tacctgcagg aatgttttca atcacataat taccatcaag atcggtaatc
    28801 gtaccctggc tggttccctc aattaacaca gaagctccaa taatagactc tcctagtttg
    28861 tctttcaccg tgcctttcaa agattttgtc tgtgccaaca ctccattcat aagaaggaag
    28921 cacaaacaca ttacaaaaac aatgcgttgt ttcat
//
