LOCUS       NZ_LR027880            19897 bp    DNA     linear   CON 25-MAR-2023
DEFINITION  Roseburia intestinalis L1-82 chromosome 1, complete sequence.
ACCESSION   NZ_LR027880 REGION: 4318380..4338276
VERSION     NZ_LR027880.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMEA4878606
            Assembly: GCF_900537995.1
KEYWORDS    RefSeq.
SOURCE      Roseburia intestinalis L1-82
  ORGANISM  Roseburia intestinalis L1-82
            Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae;
            Roseburia.
REFERENCE   1
  AUTHORS   Petit,M.-A. and Lossouarn,J.
  TITLE     Direct Submission
  JOURNAL   Submitted (03-SEP-2018) INRA, MICALIS, Domaine de Vilvert, France
COMMENT     REFSEQ INFORMATION: The reference sequence is identical to
            LR027880.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 03/25/2023 00:03:05
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.4
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,200
            CDSs (total)                      :: 4,109
            Genes (coding)                    :: 4,021
            CDSs (with protein)               :: 4,021
            Genes (RNA)                       :: 91
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 10 of 88
            Pseudo Genes (incomplete)         :: 76 of 88
            Pseudo Genes (internal stop)      :: 9 of 88
            Pseudo Genes (multiple problems)  :: 6 of 88
            CRISPR Arrays                     :: 3
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..19897
                     /organism="Roseburia intestinalis L1-82"
                     /mol_type="genomic DNA"
                     /strain="L1-82"
                     /type_material="type strain of Roseburia intestinalis"
                     /db_xref="taxon:536231"
                     /chromosome="1"
     gene            complement(1..957)
                     /locus_tag="RIL182_RS20205"
                     /old_locus_tag="RIL182_03999"
                     /db_xref="GeneID:61435214"
     CDS             complement(1..957)
                     /locus_tag="RIL182_RS20205"
                     /old_locus_tag="RIL182_03999"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006856630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate kinase"
                     /protein_id="WP_006856630.1"
                     /db_xref="GeneID:61435214"
                     /translation="MNKQYDVAALGELLIDFTENGTSGQGNPVYEANPGGAPCNVLSM
                     LNKLGHRTAFLGKVGNDIFGRQLRAAVESAGIDVSGLLTDEDVRTTLAFVETKPDGDR
                     DFSFYRNPGADMMLREDEVRHDIIADAKIFHFGTLSMTNEPVRSATRHAIKVAKENGA
                     ILSFDPNIREPLWKDMEDARTQMAYGLSVCDILKISDNEIQWFSGKEDYTEGIHMLQQ
                     TYQIPLILLSMGKDGSRAYYKDMLVEVPAFLQKNTIETTGAGDTFGACCLHHILKYGL
                     DNLTKQQLKEMLTFANAAASIITTRKGALRVMPSLEEIQRLL"
     gene            complement(1523..3775)
                     /locus_tag="RIL182_RS20210"
                     /old_locus_tag="RIL182_04000"
                     /db_xref="GeneID:61435215"
     CDS             complement(1523..3775)
                     /locus_tag="RIL182_RS20210"
                     /old_locus_tag="RIL182_04000"
                     /EC_number="3.2.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002565117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="WP_006856629.1"
                     /db_xref="GeneID:61435215"
                     /translation="MAIIIDQEQKLITLHTKNTTYQMGVGNYGQLLHLYYGKRLTGDM
                     RYLLTYYDRGFSGNPYEAECDKTYSMDALPQEYPCFGNGDFRSPAFILKNADGSYCAD
                     LRFVSCEICEGKYRIPGLPAAYDETGTESETLKVYLEDKPSGVQVTLLYGIFAELDII
                     TRAVQITNRGQEAVHIEKAASAVLDFMTGEFDVIHFHGRHGMERILERTPVEHGNQVF
                     GSRRGSSSHQQNPFVMLAGKQTGEDAGECYGCMLLYSGNFKAEAEKDQYEQTRLVMGL
                     SDEMFSWKLEPGETFDTPETAFSYSANGFSTLSWNLHRLIRSHICRSAYRDTKRPVLI
                     NNWEATYFDFTGEKIIEIAKQAAELGVEMLVLDDGWFGKRDDDLAGLGDWTVNEKKLG
                     MPLSQVAEKIRGLGMKFGIWIEPEMVCEDSDLYREHPDWAFTIPGRKPVRARYQLVLD
                     YSRKEVVDGIFAQIAKVLDDTKADYVKMDMNRHLTDIWSKTAAEQNQGAILHRYVLGV
                     YDFLERLHERYPDLLIEGCSGGGGRFDAGMLYYTPQIWCSDNTDAVERIKIQYGTSFA
                     YPSCTVGSHVSAVPNHQTGRMTELATRAAVAMAGSFGYELDLNLLTEEEKEQVREQIK
                     NYHRFEMLIRQGRYYRLTDVWQKKEYAAWEYCRPDGSEALVTVVTLDTQCNPATEYVK
                     LRGLGEDKKYRVEVVGMQTGGENGQRINGTPNSVEPEYYTGAQLVHAGLPVPRLGNEY
                     KSWQVYVKEV"
     gene            complement(3800..5482)
                     /locus_tag="RIL182_RS20215"
                     /old_locus_tag="RIL182_04001"
                     /db_xref="GeneID:61435216"
     CDS             complement(3800..5482)
                     /locus_tag="RIL182_RS20215"
                     /old_locus_tag="RIL182_04001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015561145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="WP_044998831.1"
                     /db_xref="GeneID:61435216"
                     /translation="MEEKKWWKEAVVYQIYPRSFMDSNGDGVGDLRGIKSRLSYLKLL
                     GIDVIWLSPVYQSPNDDNGYDISDYRDIMTEFGTIEDFDEMLAEAHKLGIKIVMDLVV
                     NHSSDEHRWFVESRKSKDNPYRDYYIWREARDGKEPNNWGSCFGGSAWEYDQTTDMYY
                     LHMFSKKQPDLNWENPKLRQEVYDMMTWWGERGIDGFRMDVITMISKDQRFPDGVVRG
                     NEKFGDSSPYVNNGPRVHEYLKEMNEKVISRFDWMTVGEGAGAGVEDAKRYAGTNENE
                     LDMIFTFEHVNLGQTQYGKWSDGSFDLVELKKVFQKWEDGLEGVAWNSLYWDNHDQPR
                     AVSRFGNDSEEYREISAKMLATCLHFMKGTPYIYQGEELGMTNRKCRDFSEFRDIEIK
                     NAYRDFVGGGILDEETMLKFVNAIGRDNARFPMHWDDSDNAGFTTGTPWISVNENYKK
                     INAAAQVNDPDSIFSYYKKLIELRHQMEIIVYGVYKSKAIEHPDVFAYTRTLGDEKLF
                     VVCNFREQEMDFTLEDGFTGDEKVLISNYDDVVKTENGIYLRPYEAKVFYRK"
     gene            complement(5564..6541)
                     /locus_tag="RIL182_RS20220"
                     /old_locus_tag="RIL182_04002"
                     /db_xref="GeneID:61435217"
     CDS             complement(5564..6541)
                     /locus_tag="RIL182_RS20220"
                     /old_locus_tag="RIL182_04002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015561144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="WP_006856627.1"
                     /db_xref="GeneID:61435217"
                     /translation="MATLKDVAKETGLTVSTVSRVLNNRGYISEETRKKVYEAMKKLN
                     YRPNEVARSLSKQTTNTIGVIVPHIRHPYFAELISNLESQAYHYDHKILLFNSQEKNE
                     KEWEYMEMCTSNRVAGVILCSGTVGVEKFTGLNVPLITIERYLENGTAEVECDNEQGG
                     RLAAQHLIDCGCKHLIHISGVHETAMPADARAVGFRAVCEKQKVSYQIADTTAFEYNH
                     LEYHQILEKLLKENPDTDGIFASSDLIAAQLLQVCHKLSIDVPSQMKIVGFDDVNIAS
                     LTTPPITTIHQPIKEMAKMAVELLVRSGNGELVPNRTTLPVSLVVRETT"
     gene            complement(6529..8220)
                     /locus_tag="RIL182_RS20225"
                     /old_locus_tag="RIL182_04003"
                     /db_xref="GeneID:61435218"
     CDS             complement(6529..8220)
                     /locus_tag="RIL182_RS20225"
                     /old_locus_tag="RIL182_04003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015521793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="WP_006856626.1"
                     /db_xref="GeneID:61435218"
                     /translation="MEKEIYIKKGWLFIPVCATYGELPFGGKKNNRMLEIFCRENNSE
                     TKLFEFQIPAGEAEDETYPVSYYARFPVKQFTDKTLILRGDLGKAFFDRIRNEDVPET
                     EEKSLRATQGEAFRRPSIHFTPQTGWMNDPNGLVYAEGVYHLYFQHNPFDVQWENMSW
                     GHAVSRDLLHWEQKDDVLFPDETGTMFSGSGIVNDRKMLGLPEDALVFFYTAAGNNNK
                     WSAGKQFTQRIAYSTDGGETLHKIDKGVLPTVCKENRDPKVFWHEKSGAYIMTLWLEE
                     NDFGIFRSTDLLKWEQTDRLTFKEAWECPDLVCLKDEKGNETWMFWSADGFYFWGEFD
                     GYQFQTDGVRHAAYINKIAYAAQTYSNTGNRVISVPWLRFPNRGRNYTGAMGLPREFS
                     VAYKNGEKVLRQKPVREYDDSRKPVYDSTMKNVRQQDTENEALMADTAAKVADEHVSA
                     KDLFQWKFVQDTATEIQITRAQSEDILSARINQKTDFVYNAKTGELKIGEETFVTGAG
                     IRDFSLLFDDVILEVTADCGTITGIFELPETAEKFCMEKGSREKIQVFGEEVWQP"
     gene            complement(8396..9835)
                     /gene="gtfA"
                     /locus_tag="RIL182_RS20230"
                     /old_locus_tag="RIL182_04004"
                     /db_xref="GeneID:61435219"
     CDS             complement(8396..9835)
                     /gene="gtfA"
                     /locus_tag="RIL182_RS20230"
                     /old_locus_tag="RIL182_04004"
                     /EC_number="2.4.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015521792.1"
                     /GO_function="GO:0004645 - 1,4-alpha-oligoglucan
                     phosphorylase activity [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose phosphorylase"
                     /protein_id="WP_044998851.1"
                     /db_xref="GeneID:61435219"
                     /translation="MKKLENKCMLITYSDSMGHNLADLNEILDKYFKNAVGGIHILPF
                     FPSSGDRGFAPMDYHKVDPAFGDWSDVEHLAEKYYLMFDYMINHISAQSPYYKDFLEK
                     KDASEYHDLFIRYKDFWENGEPTEEQVDAIYKRKPRAPYVEAHFADGTSEKVWCTFDE
                     EQIDINCKSETAKRFIRDNLTTLCEHGAAMIRLDAFAYATKKAGTSCFFIEPDVWEFL
                     KECEDIVKPYGVTLLPEIHEHYTMQEKIAKEDYYVYDFALPMLLINALYYGQTQYLKH
                     WFEICPRKQFTTLDTHDGIGVVDVKDLLPDEEIGRTKEDIFKFGANVKKIYNTAAYNN
                     LDIYQVNCSYYSALGDEDDAYLLARAVQFFAPGIPQVYYVGLLAGKNDLKLLEETKVG
                     RNINRHYYTKEEIDAEVKRPVVAELLRMMEFRNAHPAFDGTFELETCDDDKLVIVRRN
                     GDAWAKLSADFKVKKFTITYTEDGEVHTF"
     gene            complement(9918..10781)
                     /locus_tag="RIL182_RS20235"
                     /old_locus_tag="RIL182_04005"
                     /db_xref="GeneID:61435220"
     CDS             complement(9918..10781)
                     /locus_tag="RIL182_RS20235"
                     /old_locus_tag="RIL182_04005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006856624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="WP_006856624.1"
                     /db_xref="GeneID:61435220"
                     /translation="MSRGSKVGGTKRRVLDVVGFTAIIVLFLLYMVPFILVLLNSFKQ
                     KRDIIKNPFSFITEKGYTLANYTKAFEKMEFIKAFGNSLFITGLSTLLVIIFASMVAY
                     YFTRAKNTFSRVFFALMAASMIIPFQAIMIPLVSIYGSGLHMLNHRLTLIFMHTGFAM
                     SMSVFIYQGFIKSGIPLSLEEAAYLDGCTNVQTFFKVVFPLLKPTTATLVILNVLAFW
                     NDYLLPSLVLGKKNLYTLPLSTYSFYGTYSSDYGVIMAALVLTVAPILVLYLFLQKEI
                     IDGVVAGAVKS"
     gene            complement(10781..11659)
                     /locus_tag="RIL182_RS20240"
                     /old_locus_tag="RIL182_04006"
                     /db_xref="GeneID:61435221"
     CDS             complement(10781..11659)
                     /locus_tag="RIL182_RS20240"
                     /old_locus_tag="RIL182_04006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013655264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="WP_006856623.1"
                     /db_xref="GeneID:61435221"
                     /translation="MGRKTGEKIKNLCIFALPGCLIFCAVVILPFLYGFYLTLTDWDG
                     VSKVKNIIGVQNYISVFKDTAFWSSMGLTLKYVVLSVILVNAVAFLLAYALTNGIKGQ
                     KFFRAGFFTPNLIGGVVLGFIWQFVFSRVLVNMGKSTGWGLFSTSWLADPNKAFWSMV
                     IVTVWQLSGYMMLIYIAGFTGLSTDVLEAASIDGATGFQKMKSIILPLMVPSFVICLF
                     LTLSRAFMVYDVNLTLTGGEPYGSTRLVAMYVYEKAFTSRNYGVGQAEALILFIIVAC
                     ISGAQIYIGKKKEVEA"
     gene            complement(11793..13187)
                     /locus_tag="RIL182_RS20245"
                     /old_locus_tag="RIL182_04007"
                     /db_xref="GeneID:61435222"
     CDS             complement(11793..13187)
                     /locus_tag="RIL182_RS20245"
                     /old_locus_tag="RIL182_04007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015521789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="WP_006856622.1"
                     /db_xref="GeneID:61435222"
                     /translation="MKAKKVVAVFMTAAMTMGMLAGCGSNNSTGTANAGSNSAESKSD
                     AGESTDAAGTESAGSTDTSDLAGTQITMLNSKAEIQTALEDMAEAFKEDTGIELEVQA
                     CGTGESPYTRITSAYNSGTAPTMAIIDATDVVALASQYAVDLSDEEWVKECVNQTTQV
                     DGKIYSFPLCVEGRGIIYNKTAIEDTLGEEFDPSTINSYDALKELLENLRAGGMENPV
                     VISKEDWSLGAHQLGFIYDSYDGTTEGSAKVIDELKAGTLKAEDYDRFNEFMDTFDLL
                     SQYNINGEDPLGALYDQDPIFLADGDAALWINGCWAWPNLKEAGASDSDEYGFIPYVL
                     GNDTSDFANNGIQASAIKQLMIDAEQSTPEQQEAAKAFVNWLVYSDNGQKMLVEDAAV
                     IPACKNNTYEVLDPLGKDIQAKMAAGNTYSSSYIAPSDHWSVLGASMQKYLGGQCTRD
                     DLAADIDNYWTSQN"
     gene            complement(13621..17739)
                     /locus_tag="RIL182_RS20250"
                     /old_locus_tag="RIL182_04008"
                     /db_xref="GeneID:61435223"
     CDS             complement(13621..17739)
                     /locus_tag="RIL182_RS20250"
                     /old_locus_tag="RIL182_04008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006856621.1"
                     /GO_function="GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endo-1,4-beta-xylanase"
                     /protein_id="WP_242655525.1"
                     /db_xref="GeneID:61435223"
                     /translation="MKRNWKAGVCAALCSAMVFTGIGPVLTPYLENAVVYADENENSG
                     VKKVFTADQLKVAWGDADYELADGQWKLSFAKQYNQVKWTLPESIEMSQVNAVTFQVA
                     DQKVPISLKVYNGGDDATAANTQYGLSGQTEYTINPSGDGAIDAVGIMITEDKPENAT
                     VSLVSVTFELKAGAGDAKLGDNIIKNGDFAASEAAESWNSAAGESVVSVAAEEEEIAD
                     SGLKTYGVLTRNQETATPGDCFSQDITDAVEKGETYKFSFWAKLSDDYKDAPEEQRNV
                     EFAPFYVSGGEATYLGSYSAGILSGDCTKTLKAGEWTKYEGTFKIPKAADQVVIRIIE
                     QGTNYGQGDCVKGTYYVTGVSMNKIEREKPSIEKDIPDWKESVKAALGNDVVAGTAVT
                     GDEINDDTLMELVEKHFNAVTLGNELKPDALFNYQLEDKVNTKTIQFKGQDLEVPVVN
                     EAGDSLDFSRADKLINKICEWNNENPDNKIRIRGHVLVWHSQTQEWFFHENYDKTKPY
                     VDKETMNRRLEWFISSVFDHYFGEAANGKYDGLFYGWDVVNEAVIGNSYRTDTVSAAE
                     SLDEIRHGNNSSWWHVYKSNEFIINAFRYANQYAPKNVELYYNDFGETDNTKCEGIVK
                     LINDVKAADGTRLDAFGMQAHYSVDSFSATQFKTVAEKYAKAAGKVQLTELDFKSSAS
                     YTSGMATKESEYTKIAYCHKQLFDAIKGLKADGSNVSGLTVWGVIEPNSWLHEQSGVG
                     GGADGSAQCPLLFDGNYKAKPAYWAYVDASRLQPSIQDVVAAEKKGDAVTGKTYSIMQ
                     NDITASFISMWDKDGLTVQVTVEDAVKDDNDAVAVYVDSANSGKDDITPVTVTVKRSE
                     AAEVENGYQATIKVPLSGLSVAKVIGMDVVVTNGDKTAAFNDLTGKQGTSSKYYAKVT
                     MKPGVEKAAYGTVTVDGDKDAVWDNAGTIPITINLGSNVSANAKLLWDKDNFYVYAEI
                     KDPVLNNTNGDAWEQDSLEVFIDENNGKSNSYEYDDKQYRISYANDHSFNGKKCLEEN
                     MKSVAKITSDGYVVEASFKWTDITPKAGDEIGLEFQINDADASGKRIGTLSWNDETGM
                     GWSKPEVFGTVKLGEIKNAPEKDTEKKPETEKKEVKVKKITLNKTKAGMKKGATLTLK
                     AVVSPSDADIKDVKWTSSNKKVATVDKHGKVKALKNGVTTITATAKDGSRVSASCKIT
                     VGYKITYKLGKGKNSSKNPEYYYNEKVNLKSASKKGYVFKGWYTDSKYTKRIKTISKS
                     SKKNLTLYAKWQKVTVKKSAIKKMKAVSGRKAKVTVQKVDGAAGYQIVYSTDKQFKKN
                     VKKVTISGTSKTLGKLAKGKTYYVKVRAYKKDSTGAKVYGSFSSAKKIKISK"
     gene            complement(18044..19897)
                     /locus_tag="RIL182_RS20255"
                     /old_locus_tag="RIL182_04009"
                     /db_xref="GeneID:61435224"
     CDS             complement(18044..19897)
                     /locus_tag="RIL182_RS20255"
                     /old_locus_tag="RIL182_04009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015561141.1"
                     /GO_function="GO:0015926 - glucosidase activity [Evidence
                     IEA]"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase 53 family protein"
                     /protein_id="WP_006856619.1"
                     /db_xref="GeneID:61435224"
                     /translation="MKSGMVKRMLAAALAATLIVTSAGTTDVWAAGSEETVSVSVEET
                     EESTENVKTASSSNLITNGDFETDASGWTFLLGGGDYSPNLKKGTDTGMTNNTTGYIN
                     IWSENEAEFVMSQEITGLSAGNYTAMLSIDGANDKTADLKFYAGDESTVLSTENGWNN
                     WSTFKVENIVVDESGSIIIKIAGTLGAGYWFDVDDITLTKNLSDGEEKTEAAEALNTL
                     ITACEALTESDYTSDTWSALQTALTSAKAVYGDKDNKTVEELTEAKTVLQAAKDALVD
                     AGIVDTGADGIFVQKVDGLSNDFIKGVDVSSYVSLRDSGVTFKDWNGNVIGDQEFFSQ
                     LKEAGVNYVRIRVWNDPYDSNGKGYGGGNNDLAKAKKIGKWATDAGMKVLIDFHYSDF
                     WADPGKQKAPKAWAGYTIDQKVTAVSDYTTASITELLDAGVDVGMVQVGNETNNGVCG
                     ESTWENMCRIFDAGADAVHAAGEAKGKNILVAVHFANPEKSANYATYAKNLNTYDVSY
                     DVFASSYYPYWHGTLDNLTSTLKNIADTYDKKVMVAETSWATSLEDGDGHENTVRKGN
                     NDTKVDGMDYTFSIQGQANEVRSVISAINNIGDNGKQTFKRQDLLCQSACL"
ORIGIN      
        1 ctacaacaat ctctgaatct cctccaacga cggcatgaca cgcagggcac cttttcttgt
       61 tgtaatgatg gatgctgctg cattggcaaa tgtgagcatt tcttttaact gctgttttgt
      121 aaggttatct aagccatact ttaatatatg gtgcaggcag catgccccaa aggtgtctcc
      181 ggcaccggtg gtttcgatcg tgtttttctg taaaaatgca ggaacttcaa ccagcatatc
      241 cttataatag gctctgcttc cgtcctttcc catggataaa aggatgagcg ggatctgata
      301 ggtctgctgc agcatgtgga tcccttcggt gtaatcttct ttcccggaaa accactggat
      361 ctcattgtcc gaaattttta agatatcaca gacggataaa ccatatgcca tctgcgttct
      421 tgcatcttcc atgtctttcc agagcggctc cctgatattc ggatcaaagg aaagaatcgc
      481 gccgttttct tttgcgactt taattgcatg tcttgtcgca cttctgaccg gttcattggt
      541 catggatagt gtgccaaaat gaaagatttt tgcatctgca ataatgtcat gcctgacctc
      601 atcctcccgg agcatcatat ctgcacccgg attccggtaa aaggaaaaat cgcggtcgcc
      661 gtccggcttt gtctcaacaa acgcaagcgt ggtgcgtaca tcctcatctg tcagaagtcc
      721 gctcacatca attccggctg attccacggc agcacgaagc tgtctgccaa aaatatcatt
      781 tccgactttt cctaaaaatg cggtgcgatg acctaactta tttaacattg aaagtacatt
      841 acacggtgcc cctcccggat ttgcctcata gaccgggttg ccctgaccac tggtgccgtt
      901 ttctgtaaaa tcgattaata gctcgccgag agcggctaca tcatattgtt tgttcattta
      961 tgtgctcctt tctgctatgt taagctaatg caaagttctg gtttggtttg ttggaacgtt
     1021 gagagaacgg cacagattta acgaaggcac gctctcgctg cctgtcgctc gcagcggata
     1081 ctaagtgagc aaaatacgct cactaagtac cggcggctcc ccagcacctt cttataaatc
     1141 cgtgccgttc tctcaactgc ctgcagtctg tggcagattt cgccctggct tctcggtagt
     1201 gactgacgaa tatctccgca aaaggcgtgc cgcaaggtaa tggctggcaa attgagcgaa
     1261 gccggggctg cttttgtgac tttggtagaa aattagaaaa acttagtatg cctgttaaca
     1321 cacagtgttg tgccgccacg gacggcagcc caagtcctaa tgtgcccgga tggcacattt
     1381 aggacgcaca cgtcactccg ccacacaccc ccgcaggcat acttagcttt tcttattttc
     1441 ggacatcgga acaaaacacg ccccggcttc gctcaatttg ccttcacagc acctccggca
     1501 tccacctttc catatatttt ccttacactt ccttaacgta cacctgccac gacttatact
     1561 cattcccaag ccgcggaacc ggcagccccg catgcacaag ctgtgcccct gtatagtact
     1621 ccggctcaac agagttcggt gtcccattga tccgctgccc attttcgcca ccggtctgca
     1681 ttccgacaac ttccacccgg tactttttat cttcgccaag tccccgcaac ttcacatact
     1741 ccgtcgccgg attacactgc gtatccagcg ttaccacagt aaccagcgcc tcgcttccat
     1801 ccggcctgca atactcccac gcagcatatt cttttttctg ccagacatct gtcagcctgt
     1861 aatacctgcc ctgccggatc agcatctcaa aacggtgata gtttttgatc tgctctctga
     1921 cctgttcctt ttcttcttcc gtcagcagat ttaagtccag ttcataacca aaactgcccg
     1981 ccatggcaac tgctgcccgt gtcgcaagtt ctgtcattct tccggtctga tggttcggaa
     2041 ctgccgacac atgggaaccg accgtgcagg acggataggc aaaggatgtt ccatactgta
     2101 ttttaatacg ctcaaccgca tccgtattgt cactgcacca gatctgtggt gtataataca
     2161 acattcccgc atcaaacctg ccgccgccac cgctgcatcc ctcaatcaga agatccgggt
     2221 aacgttcatg cagccgttcc aaaaaatcat aaacaccgag cacatagcgg tgcaggatcg
     2281 caccctgatt ctgctctgcc gccgttttcg accagatatc cgtgagatga cggttcatat
     2341 ccatcttgac ataatcagcc ttcgtgtcat cgagcacttt cgcaatctgt gcaaaaatac
     2401 cgtccaccac ttcttttctg gaatagtcga gcacaagctg atagcgtgca cgcaccggtt
     2461 ttcgtccagg aatggtaaat gcccagtccg ggtgttcccg atagaggtca ctgtcctcac
     2521 agaccatttc cggctcgatc cagatcccaa atttcatgcc aagcccacga attttttctg
     2581 caacttgtga aagcggcatg ccaagttttt tctcattgac cgtccagtcg cccagtcctg
     2641 ccagatcatc atcacgtttt ccaaaccacc catcatcgag caccagcatc tccacgccaa
     2701 gctccgccgc ctgttttgcg atctctatga ttttttctcc ggtaaaatca aaataagttg
     2761 cctcccagtt attgatcaga accggtcttt tggtatcgcg gtatgcactg cggcagatgt
     2821 ggctgcggat cagacgatgc agattccacg aaagtgttga aaaaccattt gccgaataac
     2881 taaatgccgt ctccggtgta tcaaacgtct ctcccggctc taatttccag gagaacattt
     2941 cgtcggacaa gcccataaca agcctcgtct gctcatactg gtctttttct gcctccgcct
     3001 taaaattgcc gctgtacaaa agcatacagc cgtaacattc accggcatct tccccggtct
     3061 gttttcccgc cagcatcaca aacggattct gctgatggct ggatgacccg cgcctgcttc
     3121 caaatacctg attgccatgc tccaccggcg tacgctctaa gatccgctcc atcccgtgtc
     3181 tgccatgaaa atgaatcaca tcaaattctc cggtcataaa atcaagtaca gcgcttgctg
     3241 ctttttcaat atgaacagcc tcctgccccc ggtttgtaat ctgcacagcc cttgtaataa
     3301 tatcgagctc tgcaaatata ccataaagca gtgtcacctg cacgccactt ggcttgtcct
     3361 ccagatatac ctttaaagtc tcactctccg tccccgtctc gtcataagct gccggaagac
     3421 ccggtatccg atattttccc tcacaaattt cgcaggatac aaaccgcaga tcggcacagt
     3481 aacttccatc cgcatttttc aggataaatg ccggactgcg gaaatccccg tttccaaaac
     3541 acggatactc ctgtggcagt gcatccatgg aatatgtctt gtcgcactcc gcctcatacg
     3601 gattgccgga aaatcccctg tcataatagg tcagaagata ccgcatatcg cctgttaaac
     3661 gttttccata ataaagatgg agcaactgcc cgtaattgcc gactcccatc tggtaagtcg
     3721 tattttttgt atgcagtgtg atcagtttct gctcctgatc tatgatgatt gccatagttt
     3781 ttccccttcc actccaaact tatttccggt aaaatacctt tgcctcgtaa ggtcttaaat
     3841 agatgccatt ttctgttttt accacatcgt cataattgct gatcaggact ttctcgtccc
     3901 cagtaaaacc gtcttccagg gtaaaatcca tctcctgctc cctgaaattg cagaccacaa
     3961 acagtttctc atctccaagt gttctggtgt acgcaaacac atccgggtgt tcaatcgcct
     4021 tactcttgta tacaccatac acaataatct ccatctgatg acgcagttcg atcagtttct
     4081 tataataaga aaatatagaa tccggatcgt ttacctgtgc tgccgcattg atctttttat
     4141 aattctcatt gacagagatc cacggtgttc ctgtcgtaaa tcccgcattg tcactgtcat
     4201 cccagtgcat cgggaatctt gcattgtcac ggccgatggc attgacaaat tttaacatgg
     4261 tctcctcgtc caaaataccg cccccgacaa aatcacggta tgcatttttg atctcaatat
     4321 cgcggaactc cgaaaaatcc ctgcatttcc ggtttgtcat tccaagttcc tcgccctgat
     4381 aaatataagg tgttcccttc ataaaatgca gacaggttgc aagcattttt gcagagatct
     4441 cgcggtactc ctcactgtca tttccaaatc ttgacacggc tcttggctga tcgtggttat
     4501 cccagtaaag actgttccat gccacacctt caagtccgtc ctcccatttc tgaaatacct
     4561 ttttgagctc caccagatca aaactgccgt cactccattt gccatactgt gtctgtccga
     4621 gattgacatg ctcaaatgtg aagatcatat ccagctcatt ttcgtttgtt ccggcatagc
     4681 gttttgcatc ttcaacgcct gctccggcac cttcgccgac tgtcatccag tcaaatctgg
     4741 agattacctt ttcattcatc tcttttaaat actcatgtac acgcgggcca ttgttgacat
     4801 aaggagaaga atccccgaat ttttcattgc cacgcaccac accgtccgga aaacgctggt
     4861 cttttgatat catcgtaatg acatccatac gaaatccgtc gatgccgcgc tcgccccacc
     4921 aggtcatcat gtcatagact tcctgtctga gttttggatt ttcccagttg agatccggct
     4981 gttttttgga aaacatgtga agataataca tatccgttgt ctgatcgtac tcccatgcgg
     5041 atccaccaaa acaggaaccc cagttattcg gttcttttcc gtctcttgcc tcacgccaga
     5101 tataataatc gcggtacggg ttatccttac tttttctgct ctccacaaac caccggtgct
     5161 catcggaact gtggttgacg accagatcca tgacgatctt aatgccaagt ttgtgtgcct
     5221 cggcaagcat ttcatcaaaa tcttcgattg taccaaactc cgtcatgata tctctgtaat
     5281 cactgatatc gtaaccgttg tcatcgttcg gagactgata gaccggggat aaccagatca
     5341 cgtcaattcc caataatttt aaataagaca gccggctctt aatgccgcga agatcgccga
     5401 caccatcacc attgctgtcc ataaagctgc gcggatagat ctggtagact accgcttctt
     5461 tccaccattt tttttcttcc ataggaatcc tccattcctg cgccggtttt gcgcatgcac
     5521 tatttacctt cctgttatat atctggttca tatacatatt gaatcaagtc gtctccctta
     5581 ccacaagtga taccggcaga gtagtgcggt tcggcacaag ttccccgtta ccggaacgga
     5641 cgagcagttc caccgccatt tttgccatct ctttgatcgg ctgatggatc gtcgtgatcg
     5701 gtggcgttgt taatgatgca atattgacat catcgaaacc cacgatcttc atctgcgacg
     5761 gcacatcaat gctcaactta tggcacacct gaagaagctg cgctgcgatc agatcactgc
     5821 tggcaaaaat tccgtctgta tccgggtttt cctttagcag tttttcgaga atctgatggt
     5881 attcgagatg attatattca aaggccgtgg tatctgcgat ctggtaagaa accttctgtt
     5941 tttcacagac tgcacggaaa ccaactgcac gcgcatccgc aggcatggca gtttcatgga
     6001 caccgctgat gtggatcaga tgtttacatc cgcagtcgat cagatgctgc gctgcaagac
     6061 gtccgccctg ctcattgtca cactccacct ccgctgttcc attttcaaga taacgctcga
     6121 tcgtgatcag cggcacattt aatccggtaa acttttccac gccgaccgtt ccactgcaga
     6181 gaatgactcc cgccacgcgg ttgctcgtgc acatttccat gtactcccat tctttttcat
     6241 ttttctcctg ggagttaaac agtaaaatct tatgatcata atgatacgcc tgactctcca
     6301 aattactgat cagctccgca aaatacggat gtctgatgtg cggcacgatc acaccgatcg
     6361 tgttcgtcgt ctgtttggaa agcgaacgcg ctacttcgtt cgggcggtaa ttgagtttct
     6421 tcatcgcctc atatactttt tttctcgttt cttcgctgat atatccacgg ttattcagca
     6481 cacgggaaac agtgcttacg gtaagccctg tctcctttgc cacatccttt aaggttgcca
     6541 tacttcctcc ccgaaaacct gtatcttctc tctactgccc ttttccatgc aaaatttttc
     6601 tgcagtttca ggcagttcga atatacctgt gattgtacca caatctgcag tcacttcaag
     6661 aatcacatca tcaaaaagca gagaaaaatc acggattccg gcacctgtta caaatgtttc
     6721 ttcaccgatt tttaactctc cggtttttgc attgtataca aagtcagtct tctggttgat
     6781 gcgggcactt aaaatgtcct ctgactgtgc acgggtaatc tgaatttctg ttgcagtatc
     6841 ctgcacaaat ttccactgaa ataaatcctt tgctgacaca tgttcatctg caacttttgc
     6901 tgcggtgtct gccatcagtg cctcattttc agtatcctgc tgccggacat ttttcattgt
     6961 actgtcatac acaggtttcc tgctgtcatc atactccctg accggtttct gtctgagcac
     7021 tttttcaccg ttcttatatg caacggaaaa ctccctcggc agtcccatcg ccccggtata
     7081 atttcttccg cggtttggaa atctgagcca cggaactgag atcacacgat ttcctgtatt
     7141 gctgtaagtc tgcgccgcat aagctatctt attaatgtat gccgcatgac gcacaccatc
     7201 ggtctgaaat tgatatccat caaactctcc ccagaagtaa aaaccgtctg cgctccagaa
     7261 catccaggtc tcatttcctt tttcatcttt caggcatacc agatccggac attcccacgc
     7321 ctctttgaat gtcaggcggt cggtctgttc ccattttagc agatcggtgg aacgaaaaat
     7381 gccaaaatca ttttcctcta accacagtgt catgatatag gcaccgcttt tttcatgcca
     7441 gaacaccttc ggatcacggt tttctttaca aaccgtcgga agcacacctt tgtcaatttt
     7501 atggagtgtc tccccgccat ccgtactgta tgcaatgcgc tgggtaaact gtttccctgc
     7561 gctccattta ttattatttc cggctgccgt atagaaaaat accagcgcat cttccggcag
     7621 tccgagcatc ttacgatcat ttacaatacc gcttccggaa aacatcgttc cggtctcatc
     7681 cgggaaaagt acatcatcct tctgctccca gtgcagtaaa tccctgctta ccgcgtgtcc
     7741 ccagctcata ttttcccact gcacatcaaa cgggttatgc tggaaataca aatgatacac
     7801 gccctctgca tacacaaggc cattcggatc attcatccat ccggtctgcg gtgtaaaatg
     7861 aatcgaaggg cggcggaaag cctcaccctg cgtagcacgg agagattttt cttccgtttc
     7921 aggtacgtcc tcgtttctga ttctgtcaaa gaaagctttc ccaagatccc ctcttagaat
     7981 tagtgttttg tcggtaaatt gctttaccgg aaaacgggca taataactga cagggtatgt
     8041 ttcatcctct gcctctcccg ccgggatctg aaactcaaac agctttgttt cgctgttatt
     8101 ctcccggcag aatatctcaa gcatacggtt gttttttttg ccgccaaacg gcagctcgcc
     8161 atacgtggca cagaccggaa taaacagcca cccttttttg atgtatattt ccttttccat
     8221 gtcttacaac ctcctactta tatttttcct ttttaaccag cacttgtaca cacataactt
     8281 attttttctt tataatgctt gtacgcacat aacttatctt gcattggtta acatattctt
     8341 gcatttttct tattcgtact actaataaca ttgacaccct attgtgcaat tatcttcaaa
     8401 acgtgtgaac ttctccgtct tctgtataag tgatcgtaaa cttcttcacc ttaaagtcag
     8461 cggaaagttt tgcccacgca tcaccgtttc ttcgcacgat cacaagctta tcatcgtcac
     8521 aggtttccag ttcaaatgtt ccgtcgaatg ccgggtgagc attacgaaat tccatcatgc
     8581 gcagaagttc tgccacgacc ggacgtttta cttccgcatc gatctcttct tttgtataat
     8641 aatgacggtt gatgttccgt cccactttcg tctcttccaa aagttttaag tcattctttc
     8701 ctgccagcag tccgacatag taaacctgcg gaatacccgg tgcaaaaaac tgaaccgctc
     8761 tcgctaacag atacgcatca tcctcatcac caagtgcgga ataataagaa cagttgacct
     8821 gataaatgtc aaggttattg tacgctgcgg tattatagat tttcttgaca tttgcaccaa
     8881 acttaaagat atcctccttg gtgcgcccga tttcctcatc cggcagcaaa tctttgacat
     8941 ctaccacacc gattccgtca tgcgtatcaa gtgttgtgaa ctgtttgcgc gggcagatct
     9001 caaaccagtg ttttaaatac tgtgtctgtc catagtataa tgcattgatg agcagcattg
     9061 gaagtgcaaa atcgtataca tagtaatctt cttttgcgat cttctcctgc atcgtgtaat
     9121 gctcatgaat ttccggtaaa agtgtgactc cgtaaggctt tacgatatcc tcacactctt
     9181 ttaagaactc ccatacatcc ggctcaatga aaaagcagct tgttccggct tttttggttg
     9241 cataggcaaa tgcgtcgagg cggatcattg cagcgccatg ctcacacaat gtcgttaagt
     9301 tgtcgcggat aaaacgtttt gctgtctcag atttacagtt gatatcgatc tgctcttcat
     9361 caaacgtgca ccatactttt tcagatgttc cgtctgcaaa atgtgcctcc acatacggtg
     9421 cacgcggctt tcttttgtag attgcatcca cctgctcctc ggtcggctcc ccgttttccc
     9481 agaaatcttt gtagcggatg aacaggtcat gatactcaga tgcatctttt ttctccagaa
     9541 agtctttgta atacggactc tgtgccgaaa tatgattgat catataatca aacatcaggt
     9601 aatacttttc tgccagatgt tccacgtcgc tccagtctcc aaatgccgga tcgactttgt
     9661 ggtaatccat cggtgcaaat cccctgtctc ccgaagaagg gaagaacgga aggatatgga
     9721 tcccgcccac tgcattttta aaatatttat ctaagatctc gtttaagtct gccagattat
     9781 gtcccatcga atccgaataa gtaatcagca tacatttgtt ttccaacttt ttcatatcag
     9841 tctccatttc tgcataaaat cctgttttta tgctcaccac catttcactg ctgccacttc
     9901 acaggaataa tactctttta tgatttcacc gctccggcta ccacgccatc gataatctct
     9961 ttctgcagga acagatataa taccaggatc ggtgcaacag taagtaccag tgctgccatg
    10021 atcacaccgt aatcggatga gtaagttccg tagaaagaat aagtggataa cggaagtgta
    10081 tataagtttt tctttccaag taccagtgaa ggaagcagat agtcgttcca gaatgccagt
    10141 acgtttaaga tcacaagggt tgccgtagtc ggttttaaca gaggaaatac gaccttgaaa
    10201 aatgtctgta cattggtaca tccatccaga tatgccgcct cctccagtga aagcgggata
    10261 ccgctcttaa taaatccctg ataaatgaat actgacatac tcatcgcaaa tccggtatgc
    10321 ataaagatca gtgtcagtct gtggtttaac atatgaagtc cggaaccgta aatggaaact
    10381 aacgggatca tgatcgcctg gaatggaatg atcatggatg ctgccatcag tgcaaagaat
    10441 actctggaaa atgtattttt tgcgcgggta aaataatatg ctaccataga tgcgaaaatg
    10501 atgacgagca atgtgcttaa gcctgtgata aacagggagt ttccaaacgc ttttatgaat
    10561 tccattttct caaatgcttt tgtatagttt gcaagtgtat atcccttttc tgtaataaag
    10621 gaaaatggat tcttgatgat atcacgtttc tgtttaaagg agtttaacaa caccagaatg
    10681 aacggtacca tataaagcag gaataaaaca atgatcgctg taaagccaac aacatccaat
    10741 acacggcgtt ttgtcccgcc aacttttgaa cctctgctca ttatgcctct acctccttct
    10801 tctttccgat atagatctgt gcaccgctga tgcatgcaac aatgataaat aagatcagtg
    10861 cttcagcctg gcctacgcca taatttctgg atgtaaatgc cttttcatag acatacatcg
    10921 caaccagtct ggtggaaccg taaggctcac cgcctgtcaa tgtaaggttt acatcgtaaa
    10981 ccatgaatgc tctcgataag gtaaggaaca gacagataac aaacgacggc accatcagcg
    11041 gtaagataat gctcttcatt ttctggaaac ctgttgcccc atctatgctg gctgcctcaa
    11101 gcacatctgt ggacagccct gtgaaaccgg cgatgtagat taacatcata taaccggata
    11161 attgccaaac tgtaacgatc accatggacc agaatgcttt attcggatcc gctaaccagg
    11221 aagtggaaaa taatccccag cctgtgctct ttcccatgtt tacaagcact cttgaaaata
    11281 cgaactgcca gataaatcca agtacgacac caccgatcaa attcggtgta aagaaaccgg
    11341 cacggaaaaa tttctggcct ttgattccgt ttgtcagtgc atatgctaaa aggaatgcta
    11401 ctgcattgac taagattacc gataaaacta catattttaa agtaagtccc atagaggacc
    11461 agaatgccgt atctttaaat acggaaatat aattctgcac gccgataata ttttttactt
    11521 tgctgactcc atcccaatcg gtcagtgtca ggtaaaaacc atacaggaaa ggcagtatga
    11581 caactgcaca gaaaattaga catcccggca gtgcaaagat acatagattt ttaatttttt
    11641 ctcccgtttt tctacccata accctaattc ctttctgata tccccacgga aactgccatc
    11701 atgctttttc agatggcatt cccgcagaga tgatatatgg ctgtgatccg tacggtcacg
    11761 ctcagatatt tttgtttttt ctttagatac gattaattct gtgatgtcca gtagttgtcg
    11821 atgtctgctg caagatcatc tcttgtacac tgtccgccaa ggtatttctg catggaagct
    11881 ccaagtacgc tccagtggtc agaaggtgcg atatagctgg atgaataggt gtttcctgct
    11941 gccatttttg cctgaatgtc ttttccaagc ggatctaata cttcataagt attgttttta
    12001 catgccggga tcactgctgc gtcttctact aacattttct gtccgttgtc agagtatacc
    12061 agccagttga caaatgcctt tgccgcctcc tgctgctccg gtgtggactg ctctgcatcg
    12121 atcattaact gtttaattgc gcttgcctga ataccgttgt ttgcaaaatc agaagtatca
    12181 tttcctaaaa catatggaat gaatccatac tcatcactgt cagaagcgcc tgcctctttt
    12241 aagtttggcc aagcccagca tccattgatc cagagagcgg catcgccgtc agctaagaag
    12301 atcggatcct gatcgtaaag agcgcctaaa ggatcctctc cgttgatgtt gtactggctt
    12361 aataaatcaa aagtatccat gaactcgttg aatctgtcat aatcttctgc ctttaatgta
    12421 cctgctttta actcatcgat cactttggca cttccctctg tggttccgtc gtaggaatca
    12481 tagataaatc caagctgatg tgcgcctaaa gaccagtctt ctttggagat aacaaccgga
    12541 ttctccatgc cgcctgcacg aaggttttca agcagttcct ttaatgcatc gtaggaattg
    12601 atggtggatg gatcaaactc ttctcctaaa gtatcctcga tcgctgtttt attgtaaatg
    12661 attccacgtc cctcaacaca gagtgggaag ctgtatatct ttccgtcaac ctgtgtggtc
    12721 tggtttacac actcttttac ccactcttca tcggagagat caactgcata ctgggaagca
    12781 agtgcaacaa cgtctgtggc atctatgatc gccattgtcg gtgctgttcc tgagttgtat
    12841 gcgcttgtaa ttcttgtata cggagactca ccggttccac atgcctgaac ctcaagctcg
    12901 attcctgtat cttctttaaa cgcctctgcc atatcttcaa gtgctgtctg gatctcagct
    12961 ttactgttta acatggtgat ctgtgttcct gccagatctg atgtatcagt gcttccggca
    13021 ctctctgttc ctgctgcatc tgtgctctca ccggcatcac ttttgctctc tgcgctattg
    13081 ctgcctgcat ttgctgtacc tgtactgttg ttgcttccgc agcctgctaa catccccatt
    13141 gtcattgctg ctgtcatgaa tactgctacc actttttttg ctttcattgt ttttcctcca
    13201 ctctttcatg atctaaaata tgattggttc ccgttcccat tttactaatt ctttttggct
    13261 gtccgtcatc gctgtcctta ctgtgccctt actttaacac cgctttttgt ttatgtcaag
    13321 cggttgacat atgatttgtc agttataatc aaataattac attatttttt gtacatattt
    13381 acaataaatt ttttgcattt ctaatcattt ctaggtattt agaactatta tagcgtgcta
    13441 ttttatgcca atcggttgac attttaaatt ttatcaattc cgattcctgt ttatggtact
    13501 ggaaaaacac acacctatca tgcaaagcaa aaagaggacc tcacaactta gttgcaaaat
    13561 cctctttccg gtgtgccaca cattttactg tatgacgggt atattaaatt tatttgggaa
    13621 ctacttactg atctttatct tctttgcact gctgaaactt ccataaactt ttgctcctgt
    13681 ggaatctttc ttataagcac gtacttttac ataatatgtc ttgccttttg ccaattttcc
    13741 aagtgttttt gatgtgcctg atattgttac tttctttaca ttctttttga attgcttatc
    13801 cgtagaataa acgatctgat atccggctgc accgtccact ttctggactg taacttttgc
    13861 ttttcttccc gaaacagctt tcattttctt aattgcagat ttctttacgg tcactttctg
    13921 ccatttcgca tataaagtaa gattcttttt gctgctcttt gagattgttt taattctctt
    13981 tgtatacttg ctgtctgtat accagccctt aaagacatat ccctttttgg aagcagattt
    14041 taaatttacc ttttcattgt aataatattc cgggtttttg ctgctgtttt taccttttcc
    14101 taacttatag gtaattttat aacctaccgt gatcttacag gacgcgctta ctctgcttcc
    14161 atcttttgcc gttgccgtga tcgtggtcac accatttttc aatgctttta ctttcccatg
    14221 cttatcaaca gtcgcaactt ttttgttgga agatgtccac ttaacgtctt taatatctgc
    14281 atcagatggt gaaacaacag cctttaatgt aagcgttgca ccttttttca ttccggcttt
    14341 tgttttattt aacgtgattt ttttaacttt tacttctttc ttctctgttt ccggtttctt
    14401 ttctgtatct ttctccggag catttttaat ttctccaagt tttacagtac caaatacttc
    14461 cggtttagac catcccattc ctgtttcatc gttccagctc aatgtaccaa ttcttttgcc
    14521 acttgcatca gcatcattga tctgaaattc aagtccgatc tcatctccgg cttttggtgt
    14581 gatatccgtc catttaaatg acgcttcaac aacatatccg tcagaagtta tttttgccac
    14641 agacttcata ttctcttcaa ggcacttttt gccattaaat gagtgatcat ttgcataact
    14701 gatcctgtac tgcttgtcat cgtattcata agagttggat tttccattat tttcgtcgat
    14761 aaatacttct aaggaatcct gctcccatgc atcaccgttg gtattattga ggacaggatc
    14821 tttgatctcg gcatatacat aaaaattgtc tttatcccag agtaacttcg catttgcaga
    14881 aacattggag ccgagattga ttgtaatcgg aatggttccg gcattatccc ataccgcatc
    14941 tttatctccg tctacggtaa ctgtaccata ggcagctttc tccacccctg gtttcatcgt
    15001 tactttcgcg taatatttac tgcttgttcc ctgttttcct gtcaaatcat taaatgcggc
    15061 tgttttatcc ccatttgtga ccacaacatc cattccgatc acttttgcaa cggaaagtcc
    15121 tgataacggt acctttatgg ttgcctgata accattttct acttctgctg cctcgcttct
    15181 ttttaccgtt acggtcactg gtgtgatgtc atcttttccg gaatttgcag aatccacata
    15241 aacagcaact gcatcattat catcttttac ggcatcttct accgtaacct gcacggtaag
    15301 accatcttta tcccacatcg aaataaagga agccgtgata tcattctgca tgatactgta
    15361 tgtctttcct gtcactgcat cacctttttt ctctgcagca actacatcct gaattgacgg
    15421 ctggagtctg gatgcatcta catacgccca gtacgcaggt tttgctttat aatttccatc
    15481 aaaaagcaat gggcactgcg cagagccgtc tgcaccacca ccaacaccgg actgttcatg
    15541 taaccatgaa tttggctcga tgacccccca tacggtcaat ccggaaacgt tcgaaccatc
    15601 tgcttttaag cctttgatcg catcgaataa ctgtttatgg caatatgcaa ttttagtata
    15661 ctcgctctct tttgttgcca tacctgatgt ataagatgca cttgatttaa aatcaagctc
    15721 tgtaagctgt acttttcctg cagcttttgc atatttttca gccactgttt taaactgcgt
    15781 ggcagaaaaa ctatccacac tgtaatgtgc ctgcatgcca aatgcatcca gtctggttcc
    15841 atcggcagcc tttacatcat tgatgagttt tacaataccc tcacattttg tattatccgt
    15901 ctcaccaaaa tcgttgtaat aaagctctac atttttcggt gcatactggt ttgcatatct
    15961 gaaggcattg atgataaatt cgttgctctt atatacatgc caccagcttg aattatttcc
    16021 atgacggatc tcatcgagac tttccgctgc actcacggta tctgtacggt aagagtttcc
    16081 aatgacagcc tcatttacaa catcccagcc ataaaataat ccgtcatatt ttccatttgc
    16141 agcttccccg aagtaatggt caaagacact tgaaataaac cattcaagac ggcggttcat
    16201 ggtctctttg tccacataag gtttggtttt atcataattt tcatggaaaa accattcctg
    16261 tgtctgggaa tgccatacaa ggacatgacc acggatacgg attttgttat ccggattttc
    16321 attattccac tcacagattt tatttattaa tttatctgca cgtgaaaagt ccaagctgtc
    16381 accggcttca tttacgaccg ggacttcaag atcctgtcct ttaaattgga tcgtctttgt
    16441 gttgacttta tcctctaact gatagttgaa caatgcatcc ggttttaatt cgtttccaag
    16501 tgtaaccgca ttaaagtgtt tttccaccag ttccatcagc gtatcatcat tgatctcatc
    16561 accggtcact gctgtgccgg caactacatc attgcctaaa gcagctttca cactttcttt
    16621 ccagtccggg atgtccttct caatagatgg cttttctctt tcaatcttat tcatggacac
    16681 accggtcaca tagtaagtcc cttttacgca atcgccctgt ccatagttgg ttccctgttc
    16741 tataatacgg atgaccacct gatctgcagc tttcggtatt ttgaaagttc cctcatattt
    16801 tgtccattct ccagctttta atgtctttgt acagtctcct gacaaaatac ctgctgaata
    16861 acttccaaga tatgttgcct caccaccgga aacatagaat ggtgcaaact ccacatttct
    16921 ctgctcttcc ggagcatctt tgtaatcatc ggacaatttc gcccagaatg agaatttgta
    16981 tgtttcccct ttttcaaccg catccgtgat atcctgcgaa aaacaatccc caggggtggc
    17041 agtttcctga ttacgtgtaa gtacaccgta tgttttaaga ccggaatctg cgatttcttc
    17101 ttcctctgct gcaactgaaa caaccgattc tccggctgca ctgttccatg actccgccgc
    17161 ttcggacgct gcaaaatcac cgttttttat aatattatcc cccaattttg catcgcctgc
    17221 tcctgctttc agttcaaagg tcacgctcac aagacttacc gttgcatttt ccggtttatc
    17281 ttccgttatc atgattccga ctgcatcaat agcgccatcc cccgatggat ttatcgtata
    17341 ctccgtctgt ccgcttaatc cgtactgtgt attagctgct gttgcatcat ctccaccgtt
    17401 gtatactttc agactgatcg gtactttctg atccgccacc tgaaatgtaa cagcattcac
    17461 ctgtgacatt tcgatactct ccggcaacgt ccatttcacc tgattatact gttttgcaaa
    17521 agacaatttc cactgtccat ctgcgagttc ataatccgcg tctccccatg ccactttcag
    17581 ctgatctgca gtaaaaactt tttttacccc tgaattttcg ttttcatctg catagacaac
    17641 tgcattttca agatatggtg tcagcaccgg tcctatcccg gtaaaaacca tagcactgca
    17701 caaggctgcg catacccctg ctttccaatt tcgtttcaaa ccccgttctc ctccttttat
    17761 atattttcta ccgttacaaa tttatgttag cagaagaaaa tattaaaaat agaggaattt
    17821 ttatagaaaa aaaccggaca gataatagaa tacactctct gccgacatcc attatcatga
    17881 gttaaaaaag tggagaatcc tgcaaaaaac aaaattctcc actttctatc atgtttttac
    17941 cacatgacat atattataaa tttacttttt gggctactta ctgatcttta ccttcttcac
    18001 actgctgaaa cttccataaa cctttgcgcc tgtggaatct ttcttatagg cacgcacttt
    18061 gacataataa gtcttgcctt ttgaaagttt gcttaccatt gtcaccgata ttgttgatcg
    18121 ctgaaataac acttcttact tcatttgcct gtccctgtat ggaaaatgta taatccatac
    18181 catctacttt tgtatcatta ttacctttac gaacagtatt ttcatgtcca tcgccatcct
    18241 ctaaacttgt tgcccaggat gtctctgcta ccattacttt tttgtcataa gtatcagcga
    18301 tattctttaa agtactggta agattgtcaa gtgttccatg ccagtatgga taataagaag
    18361 atgcaaatac atcatagctt acatcatatg tattcagatt ttttgcataa gttgcatagt
    18421 ttgcgctttt ttccggattt gcaaaatgaa cagcaaccaa gatattcttt ccttttgcct
    18481 ctcctgctgc gtgaaccgca tctgcaccgg catcaaagat cctgcacatg ttttcccatg
    18541 tactctcacc acagacaccg ttgtttgtct catttccaac ctgaaccatt ccaacatcaa
    18601 cacctgcatc taacagttct gtaatgctcg ctgttgtata atcagataca gctgtcactt
    18661 tctgatcgat cgtataaccc gcccaggctt tcggcgcctt ctgttttccc ggatctgccc
    18721 agaaatcaga ataatggaaa tcaattaaca ccttcatgcc tgcgtcggtt gcccattttc
    18781 cgattttctt tgcttttgca agatcgttat ttccaccacc gtatcctttt ccattgctgt
    18841 catatggatc attccacaca cgtatacgca catagttgac acctgcttct tttaactggc
    18901 tgaagaactc ctgatcacct atcacgttac cgttccagtc tttgaatgtc actccgctgt
    18961 ctcttaagct gacataagat gacacatcca cacctttgat aaaatcattg ctcagtccat
    19021 ctactttctg tacaaaaata ccatcagctc cggtatcaac gatgcctgca tcaaccagtg
    19081 catcttttgc agcctgcagg actgttttag cttctgttaa ttcctctacg gttttgttgt
    19141 ctttatcccc ataaactgct tttgctgatg taagcgctgt ctgtaatgca ctccaggtat
    19201 ctgaagtgta atctgactct gtcagggctt cacaggctgt gataagggta tttaaagcct
    19261 ctgctgcttc ggttttttcc tctccatcag acagattttt tgttaatgta atgtcatcta
    19321 catcgaacca gtatccggca cctaatgtac ctgcaatttt aataataata cttccgcttt
    19381 catctactac tatattttca accttaaacg tcgaccagtt attccagcca ttttccgtac
    19441 ttaatactgt actctcgtct cccgcataaa actttaaatc tgcagtttta tcatttgctc
    19501 catctatact taacatagcg gtataatttc ctgctgaaag tcccgtaatc tcctgagaca
    19561 taacaaactc ggcttcgttt tccgaccaaa tgttgatata acccgtcgta ttatttgtca
    19621 tacctgtgtc tgtacctttt tttaagtttg gcgaataatc gccaccaccc aacaaaaatg
    19681 tccatccaga tgcatctgtc tcaaaatctc catttgttat cagattactg ctgcttgcag
    19741 tttttacatt ctccgtactt tcctctgtct cttccacact cacagaaact gtctcttcgc
    19801 ttcctgctgc ccagacatcc gttgtcccgg cacttgtcac aatcaatgtc gctgccagtg
    19861 ccgctgccag catgcgcttt accatcccac ttttcat
//
