LOCUS       NZ_ACFY01000084        16455 bp    DNA     linear   CON 31-JUL-2020
DEFINITION  Roseburia inulinivorans DSM 16841 R_inulinivorans-1.0.1_Cont419.1,
            whole genome shotgun sequence.
ACCESSION   NZ_ACFY01000084
VERSION     NZ_ACFY01000084.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN00008857
            Assembly: GCF_000174195.1
KEYWORDS    WGS; RefSeq.
SOURCE      Roseburia inulinivorans DSM 16841
  ORGANISM  Roseburia inulinivorans DSM 16841
            Bacteria; Firmicutes; Clostridia; Clostridiales; Lachnospiraceae;
            Roseburia.
REFERENCE   1  (bases 1 to 16455)
  AUTHORS   Sudarsanam,P., Ley,R., Guruge,J., Turnbaugh,P.J., Mahowald,M.,
            Liep,D. and Gordon,J.
  TITLE     Draft genome sequence of Roseburia inulinivorans (DSM 16841)
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 16455)
  AUTHORS   Sudarsanam,P., Ley,R., Guruge,J., Turnbaugh,P.J., Mahowald,M.,
            Liep,D. and Gordon,J.
  TITLE     Draft genome sequence of Roseburia inulinivorans (DSM 16841)
  JOURNAL   Unpublished
REFERENCE   3  (bases 1 to 16455)
  AUTHORS   Fulton,L., Clifton,S., Fulton,B., Xu,J., Minx,P., Pepin,K.H.,
            Johnson,M., Bhonagiri,V., Nash,W.E., Mardis,E.R. and Wilson,R.K.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-FEB-2009) Genome Sequencing Center, Washington
            University School of Medicine, 4444 Forest Park, St. Louis, MO
            63108, USA
REFERENCE   4  (bases 1 to 16455)
  AUTHORS   Fulton,L., Clifton,S., Fulton,B., Xu,J., Minx,P., Pepin,K.H.,
            Johnson,M., Bhonagiri,V., Nash,W.E., Mardis,E.R. and Wilson,R.K.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-FEB-2009) Genome Sequencing Center, Washington
            University School of Medicine, 4444 Forest Park, St. Louis, MO
            63108, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 04/08/2020 14:18:27
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 4.11
            Features Annotated :: Gene; CDS; rRNA; tRNA; ncRNA; repeat_region
            Genes (total)                     :: 3,990
            CDSs (total)                      :: 3,924
            Genes (coding)                    :: 3,520
            CDSs (with protein)               :: 3,520
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 4, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 4, 3 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 404
            CDSs (without protein)            :: 404
            Pseudo Genes (ambiguous residues) :: 0 of 404
            Pseudo Genes (frameshifted)       :: 271 of 404
            Pseudo Genes (incomplete)         :: 133 of 404
            Pseudo Genes (internal stop)      :: 30 of 404
            Pseudo Genes (multiple problems)  :: 27 of 404
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence was derived from
            ACFY01000084.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Roseburia inulinivorans (GenBank Accession Number for 16S rDNA
            gene: AJ270473) is a member of the Firmicutes division of the
            domain bacteria and has been isolated from human feces. The
            sequenced strain, A2-194, was obtained from the Deutsche Sammlung
            von Mikroorganismen und Zellkulturen GmbH (DSMZ) (DSM 16841).
            This is a Newbler assembly
            (http://www.454.com/enabling-technology/the-software.asp) comprised
            of 1/4 plate of XLR fragment 454 DATA with a Q20 coverage of 15.8X.
            This sequenced strain is part of a comprehensive, sequence-based
            survey of members of the normal human gut microbiota. A joint
            effort of the WU-GSC and the Center for Genome Sciences at
            Washington University School of Medicine, the purpose of this
            survey is to provide the general scientific community with a broad
            view of the gene content of 100 representatives of the major
            divisions represented in the intestine's microbial community. This
            information should provide a frame of reference for analyzing
            metagenomic studies of the human gut microbiome. Further details of
            this effort are described in a white paper entitled 'Extending Our
            View of Self: the Human Gut Microbiome Initiative (HGMI)'
            (http://www.genome.gov/Pages/Research/Sequencing/SeqProposals/HGMIS
            eq.pdf). These studies are supported by National Human Genome
            Research Institute.
            Coding sequences were predicted using GeneMark v3.3 and Glimmer2
            v2.13. Intergenic regions not spanned by GeneMark and Glimmer2 were
            blasted against NCBI's non-redundant (NR) database and predictions
            generated based on protein alignments. tRNA genes were determined
            using tRNAscan-SE 1.23 and non-coding RNA genes by RNAmmer-1.2 and
            Rfam v8.0. Gene names are generated at the contig level and may not
            necessarily reflect any known order or orientation between contigs.
            For answers to your questions regarding this assembly or project,
            or any other GSC genome project, please visit our Genome Groups web
            page (http://genome.wustl.edu/genome_group_index.cgi) and email the
            designated contact person.
            This is a reference genome for the Human Microbiome Project. This
            project is co-owned with the Human Microbiome Project DACC.
            Product names were updated in June 2013.
FEATURES             Location/Qualifiers
     source          1..16455
                     /organism="Roseburia inulinivorans DSM 16841"
                     /mol_type="genomic DNA"
                     /submitter_seqid="R_inulinivorans-1.0.1_Cont419.1"
                     /strain="DSM 16841"
                     /isolation_source="biological product [ENVO:02000043]"
                     /host="Homo sapiens"
                     /culture_collection="DSM:16841"
                     /type_material="type strain of Roseburia inulinivorans"
                     /db_xref="taxon:622312"
     gene            complement(1..2169)
                     /gene="gnpA"
                     /locus_tag="ROSEINA2194_RS08245"
                     /old_locus_tag="ROSEINA2194_01886"
     CDS             complement(1..2169)
                     /gene="gnpA"
                     /locus_tag="ROSEINA2194_RS08245"
                     /old_locus_tag="ROSEINA2194_01886"
                     /EC_number="2.4.1.211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014078991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,3-beta-galactosyl-N-acetylhexosamine
                     phosphorylase"
                     /protein_id="WP_007885595.1"
                     /translation="MGNKEHGGRVTIPTNLDVVPETIELMKRWGADAIRDCDGTEFPEE
                     LTKTGAKIYATYYTTRKDNAWAKANPDEVQQSYIMTNFYTATGNELQIPLMKGISDELM
                     QVNTRDDRKRWWEVIDRSTGEVVSTDKWEYNEETGCVCIHDTEPFHEYTVSFLAYIIWD
                     PVHMYNAVTNGWKDFEHQITFDVRQPKTHKYSMERLRKYCAEHPYVNVIRYTTFFHQFT
                     LVFDELKREKFVDWYGYSSSVSPYILEQFEREVGYKFRPEFIIDQGYHNNQYRVPSKEY
                     KDFQAFQRREVAKLAKEMVDITHECGKEAMMFLGDHWIGTEPFMEEFATIGLDAVVGSV
                     GNGSTLRLISDIEGVKYTEGRFLPYFFPDTFHEGGDPVKEAKENWVTARRAILRKPIDR
                     IGYGGYLKLALEFPEFLDYVESVCNEFRELYENAKGTTPYCVKKVAVLNSWGRIRSWGC
                     HMVHHALYQKQNYSYAGIIEALSGAPFDVKFISFDDILENEDILKDIDVIINVGDGDTA
                     HTGGAVWENPVISSAIRRFVYEGGGFIGIGEPAGHQYQGHYLQLADLIGVEKETGFTLN
                     YDKYNWDEHPEHFILADTTKPVDFGEGKKSIYAYEGTEILVQREKEVQMAVNGFGAGRS
                     VYISGLPYSFENSRILYRSILWSTHSEEELHQWYSTNFNVEVHAYVKNGKFCVVNNTYE
                     PQNTVIYRGDGSSFALKMEANEIKWYAV"
     gene            complement(2181..3353)
                     /locus_tag="ROSEINA2194_RS08250"
                     /old_locus_tag="ROSEINA2194_01887"
     CDS             complement(2181..3353)
                     /locus_tag="ROSEINA2194_RS08250"
                     /old_locus_tag="ROSEINA2194_01887"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="3.2.1.63|GH95"
                     /protein_id="WP_044927509.1"
                     /translation="MDYLWNLKPRFEQFANEFYGVDGLLIPGVSTIDGKPMGGWSQYAL
                     SPTMSIWVALSFDEYYLYTGDVLFLKEKAYPFFYEVGKAIMGLLEEKNGKLYLPLSTSP
                     EIYDDTPEAYLIPNSNFDLALIRYLFVRLQEYSEILNKEKTAYEEILSKLDEIAVIDGY
                     IGLNRVERLKESHRHFSHLMCLYPLHLIHYDTKEHRELYKKALSEIEKLGTGMWVGFSF
                     AMCAQLYAMAENGAGAYEKLRQFADGFVEENGFHLNGDYKQKGYSTFHYRRFTLEALFG
                     FCDALQEMLLQEYRGYLHLFPAIPKQWENEGIEFNGFRSYGGILVSGKIKNGYLSEIRL
                     KIPEKMLIKIKNTFPTKRARLETDKKTQIIEETEGFFVLELEKGNAKITG"
     gene            complement(3319..3492)
                     /locus_tag="ROSEINA2194_RS21035"
                     /old_locus_tag="ROSEINA2194_01888"
     CDS             complement(3319..3492)
                     /locus_tag="ROSEINA2194_RS21035"
                     /old_locus_tag="ROSEINA2194_01888"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_007885600.1"
                     /translation="MPLQGVWTADDGKIPPWRGDYHHDTNTQLSYQAYLKADRLAEGEV
                     FFGLFMEFKTSF"
     gene            complement(3563..4405)
                     /locus_tag="ROSEINA2194_RS08255"
                     /old_locus_tag="ROSEINA2194_01889"
     CDS             complement(3563..4405)
                     /locus_tag="ROSEINA2194_RS08255"
                     /old_locus_tag="ROSEINA2194_01889"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="3.2.1.63|GH95"
                     /protein_id="WP_007885603.1"
                     /translation="MDLSKYDICYEHAITSWDMGLPLGNGRLGCIVYGEDAIYLAVDRI
                     DLWDTREHPNTLEAGFCYKNLVKLSKLRTEEAWKERERLFEKIYDELSYPSKISAGHFK
                     LDYGCELQNVHAKIDLKSAIGEMHFDGGEIELFMDAWKPVGAARIKGDFRSELCIPEYI
                     SSDCHNEREMFKDGGQITPTCGMGYPQADIKKEDGFLYYIQETKSEFSYGVFAYTVLKK
                     EFAEIYFTIKTSKDGDDFDRIAKEELKEAARTGYDKLKEEHIKWWKKILGKGFTENQR"
     gene            complement(4438..5855)
                     /locus_tag="ROSEINA2194_RS21040"
                     /pseudo=""
     CDS             complement(4438..5855)
                     /locus_tag="ROSEINA2194_RS21040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015736742.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-fucosidase"
     gene            complement(5903..6694)
                     /locus_tag="ROSEINA2194_RS08265"
                     /old_locus_tag="ROSEINA2194_01892"
     CDS             complement(5903..6694)
                     /locus_tag="ROSEINA2194_RS08265"
                     /old_locus_tag="ROSEINA2194_01892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008706708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gnl|TC-DB|Q8RJU8|3.A.1.1.18"
                     /protein_id="WP_156337721.1"
                     /translation="MILVTVIMIYPLLWNVYSSFKTNNEFLTNAFSLPKSLAWDNYARA
                     IEKSNLLSNVGNSVLIVLITLCVIMVCAVPCAYCLVRYKFFGSRLMLNIYMAAIFIQAT
                     FIMIPLFLQMNALHLLNNRVALAVLYATMQFPFAIFVLSGFLRSIPRDYEEAAMIDGCG
                     PFRILIKVIMPMAKPGIVTVCMISAMAAWNEYPVALVMLTDPEKQTLPVGLANLYEVQR
                     YATDWGALFAALILALIPTIIIFLIGQKQLIQGMNVGGLKG"
     gene            complement(6773..7672)
                     /locus_tag="ROSEINA2194_RS08270"
                     /old_locus_tag="ROSEINA2194_01893"
     CDS             complement(6773..7672)
                     /locus_tag="ROSEINA2194_RS08270"
                     /old_locus_tag="ROSEINA2194_01893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009003154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gnl|TC-DB|Q8RJU9|3.A.1.1.18"
                     /protein_id="WP_081453893.1"
                     /translation="MPEKKKKKGQKLPVGFICICVLPAFLLTLIFTIIPTIRAFLLSLT
                     NATSLGLNSKFVFLENYKYMFRDEYFILALKNTLKLMAVVPIITIAIALVLAFIISQSD
                     LKERGLYRTVFYFPNIISLTVVGIIWSFVFHPTMGILNSFLNGVGLSAWAKSWLGDGST
                     ALWCIAVTLIWQATGYYMVMHIAAMDGISSEIYEAATIDGAGPVRKMFSITLPLIKDII
                     GITFVLALSGTINLSFTLSKVMTGGGPNGASSVLLQYMYTQGFINGNFGYAMAITVFTL
                     IISIALSMVSRKLTNSES"
     gene            complement(7766..9178)
                     /locus_tag="ROSEINA2194_RS08275"
                     /old_locus_tag="ROSEINA2194_01895"
     CDS             complement(7766..9178)
                     /locus_tag="ROSEINA2194_RS08275"
                     /old_locus_tag="ROSEINA2194_01895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009003153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="STP|SBP_bac_1"
                     /protein_id="WP_007885619.1"
                     /translation="MKKAISTLLVASMCAATLAGCGGNANTSANTDNSSAENTVGTEKT
                     EKNGTADNAAEFENKKLNIAVFEGGYGPDYWNEIVEKFEAAYPGVEVDMQISPSIGDVI
                     RPQIVAGNVPDFIVMNDNDSTGLISSMIKEHALLDLTDVFEGPGIDDETPLKDQVNTGI
                     LETAKCQPYADGKIYLAPFNSSPMGLVYNKTLFEEMNYELPTTWDEFFALGDQAKEDGY
                     ALMTYAGIYPSYVESLLWPALASATGIDNIKDISNYVEGSFSKPEAMEVLENIAKIGTG
                     GYLLEGTVALNHTQSQTEMMMNKCLFIPNGNWMENEMADAPRADGFEFGLWTAPVLKDG
                     DEAYVMTSVEQFSIPAKAENPELAKEFLRFLYTEESVKLFAEKANGIYALKDATELSKG
                     LVSDGIYNMNEIYEHGTSMVFGFAALPEGCKVVPNDDVFNVLSDVMTGKMSAEEWAQKV
                     ENSFKEVSETAQ"
     gene            9370..11160
                     /locus_tag="ROSEINA2194_RS08280"
                     /old_locus_tag="ROSEINA2194_01896"
     CDS             9370..11160
                     /locus_tag="ROSEINA2194_RS08280"
                     /old_locus_tag="ROSEINA2194_01896"
                     /inference="COORDINATES: protein
                     motif:HMM:NF012876.1,HMM:NF014567.1,HMM:NF018305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gnl|TC-DB|F4LXP4|8.A.59.2.1"
                     /protein_id="WP_007885620.1"
                     /translation="MKLTKTRHCVKQTNLLRTIKIRNRLLCIFLFISLVPVTFIGFYAY
                     TVYTQSINDKLERSNEQALYLLNQNFITELNIFRMYIDTISVSDECQQILSKSCDTNFT
                     LNEQDVQALNDFRSRVPFPSIHLKNLRILDRNRNIVYDLGYDDIDAERFSQIVEEIDET
                     SPHDSLQYIHTYRSSDKIIIGRKIYSSTRLSEHIGYILIYLDETFFSNTLFTNVSFGDE
                     SNIMLVRGDGYIISSQKRSVLGALLDDALLQQVKLNKNSLAETFYTEYEGEKLVIISVY
                     NSEFNNYLMATFPYRYITDETSRINQRLLLLAAILIALCLCLTLIVYTSIMQPIHQIVT
                     KCNDISYEDLNTAINDTSPDELGFLARTIDQMLQRIHMFHIEQAQNEEQKRHLELRVLQ
                     YQINTHFLFNTLNSLRIVAQMNDVPILEQGISSLTFLLQQTLVKKQERIPLSLEIENLN
                     HYFTVQSIRYAGMFDVKYHLENDTLACEIPRFALQPLAENAIIHGTANAAIPIIISVES
                     HFSDNKTLEIILRDNGCGFDQDEVKQTDKKCGSGIGVDNVNQRIKLHYGASYGLKLESH
                     PGEGTVCYLTLPHILYKEEN"
     gene            11162..12757
                     /locus_tag="ROSEINA2194_RS08285"
                     /old_locus_tag="ROSEINA2194_01897"
     CDS             11162..12757
                     /locus_tag="ROSEINA2194_RS08285"
                     /old_locus_tag="ROSEINA2194_01897"
                     /inference="COORDINATES: protein
                     motif:HMM:NF012301.1,HMM:NF024242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DBD-Pfam|HTH_AraC,DBD-Pfam|HTH_AraC,DBD-SUPERFAMI
                     LY|0036286,DBD-SUPERFAMILY|0035607"
                     /protein_id="WP_007885621.1"
                     /translation="MSLQILLVDDEPAIKIGFRQLTDWSKTPYTLCGTAGNGKEALAYL
                     EKNPVDIIITDLKMSVMDGIGLIHALKQNNSEIPIIVLSSYSDFELVREALTAGAADYI
                     LKANISADSLIAHLDKVAGNLLNRQKDRAAALLQKQQLEEQNTQILMNDIRNFFLDETI
                     TTEELLKETSDLAFFSVPCIVLTLFFHEDMKREKLKRVAPNIQTLLTETLALAASPVSI
                     MMHHNELAFFLPYSDTLKYNISSKTQVLNRQIATYFGVLPILCYSAPAAGAAECRNAYF
                     SCINARRITFYEKNRSIIFTKDIRFVFEISAEEIQETMNSVLNFVQTGSRENLFGYVRN
                     LLAEWSALPLEPFHLCMNCVHIFEGVALSGKSGKLHAQIHDYQKKISQSTSLAELKVTL
                     CDALLLLLESNENNYENYKKEIQVVMRYVNVHYKEHITLDQIAEEANLNKSYLCRLFKK
                     EYGDSVFNYLNMIRMEKAAELLRSNPGLYVQEAAAEVGITEPFYFTRRFKEYFGISPRE
                     YILRVSDNDHSPEA"
     gene            complement(12838..15399)
                     /locus_tag="ROSEINA2194_RS19690"
                     /old_locus_tag="ROSEINA2194_01898"
     CDS             complement(12838..15399)
                     /locus_tag="ROSEINA2194_RS19690"
                     /old_locus_tag="ROSEINA2194_01898"
                     /inference="COORDINATES: protein motif:HMM:NF012956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH136|3.2.1.-"
                     /protein_id="WP_007885622.1"
                     /translation="MLAAVIVAGMVTGSMPVCVNAQETTGNAGTTYYVDAENGDDSNSG
                     TSIDAPWKSLNKVTDTTFLPGDQILLKSGSVWNGEWLWPKGSGVEGAPIIIDKYGGEEK
                     PIINGMGIDRGLNYSGAVHLRNQEYWEIRNLEITNDDDFDEDIDLSRPKGDNSWSSKNM
                     TRNGILLIVDCDQLEDDDDGIMDHIYIENCYVHDVDGPNDWNDTFTGGIIFNVVGSSLR
                     PSSSFNDLRIAYNTIRKVDLLGVTGYVTTVKGNYQDGIDANNMWMTNVYIGHNYFEDIA
                     QGAIDLCDAKDAVVEYNVVDGFLKRYPNFRPTVALYPWKCENAVFQFNEVYNGPSTNAD
                     GSPYDMDSGLKDVVYQFNYSHNNPCGWMLYMGKNNNDIIRYNISDDGGDYIIKYFLTAC
                     ETPTYFLNNVIIYDGERTKFMHRDPFKSQTYFYNNVFYNKSTTTTTTWHDTARYLGNLG
                     AVTFSNNCFYEASGIHSKYEPADAYKVTENPKMVNPGQKPERNEQGILSGATIWDGYKI
                     GKDSPLVDAGIYVPQMGTMDFFGNQLYYGDAPDIGVYEVPEGEYNAPPVNLAVKASASA
                     NNFHVSFDACNVVDGDDTTRWASADSTLPIWLELDFGEETTFNELIAKENIVSGWASAR
                     IAKFELQKWNGTEFEKFYESSETIGESAEFVFPEVTTTKLRFVITGLKADTTLHGKGQT
                     DPSLKELELYYNKQASKKVNLVLNKEVITNNCHNDFDVSWLNDGKMDTRWASANSELPI
                     EIEFNLGSDVTFNTMAMTENIVANWATPRIESFQLQAWDGTTYQTIFENTGEVGERKEF
                     AFEDTTAQKIRLVITALRADTSANSAGQTDPSIAEFELYRR"
     gene            complement(15433..16455)
                     /locus_tag="ROSEINA2194_RS08295"
                     /old_locus_tag="ROSEINA2194_01899"
     CDS             complement(15433..16455)
                     /locus_tag="ROSEINA2194_RS08295"
                     /old_locus_tag="ROSEINA2194_01899"
                     /inference="COORDINATES: protein motif:HMM:NF024545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidyl-prolyl cis-trans isomerase"
                     /protein_id="WP_007885623.1"
                     /translation="MGKRRYFYFVIGIVLLAAFSITGISLLISSPALYVENIKISKEEA
                     EFFVSEEKSASYAYFAGKYNADTSVSSFRNTQFDGITPEEYARERALKNIVETKNILLL
                     AKEAGMAESVSYSDIRKDWKEFVAARKNAVESNEIVYGPVEMSFSDYYSYYISKIKLEM
                     FEQYKVDNRLQESETRQYYESHKELFSQGDEISLLVYSVPDAADGNGESTLRQIKKEIE
                     VNGRIQSEKERIGQYDETELAIGEMSNKGDSRSNSIYLEAVYGLNAGEISDVYYDDSIG
                     YYAVRYLGRKEGSGLSYDEVRNRLEDMIMTEQFQRYLTDREEELSVTVVDRVYDTIKWN
                     "
ORIGIN
        1 ttaaacagcg taccatttaa tctcatttgc ctccattttc aacgcaaaac tgcttccatc
       61 gccgcggtaa ataaccgtgt tctgtggctc ataggtatta tttacaacac agaatttgcc
      121 attttttaca tatgcatgca cttctacgtt gaagttcgtg ctataccact gatgaagctc
      181 ttcttcgctg tgtgtgctcc ataaaatact gcggtacagg attctgctgt tctcaaaact
      241 gtatggaagt ccgctgatgt atacagagcg gcctgctcca aatccgttga cagccatctg
      301 tacttccttc tctctctgca caaggatctc tgttccctcg tatgcataga tactcttctt
      361 tccttctccg aaatctaccg gttttgtggt atctgcaaga atgaagtgtt ccggatgttc
      421 atcccagtta tacttgtcat agtttaacgt aaatcctgtt tctttctcta ccccgatcag
      481 atctgcaagc tgtaaatagt gtccctgata ctggtgtcct gccggttccc cgataccgat
      541 gaatccgcct ccttcatata caaatctgcg gatcgcagaa gaaatgaccg gattctccca
      601 gactgctcca cctgtatgtg ctgtatcacc atcacctacg ttaatgatca catcaatatc
      661 ttttaatata tcttcatttt ctaaaatatc atcaaaagaa atgaacttca catcaaatgg
      721 tgctccactt aacgcttcga taatacctgc atagctgtaa ttctgtttct ggtacagtgc
      781 gtgatgtacc atatggcatc cccagcttct gatcctgccc caactgttta atactgctac
      841 tttcttcacg caatacggtg tcgtgccttt tgcattttca tacaattcgc ggaactcgtt
      901 gcagacactc tccacatagt ctaaaaattc cgggaattcc agtgcaagtt ttaagtatcc
      961 gccatatccg atacggtcga tcggttttct taagatggca cggcgtgctg tcacccagtt
     1021 ttcctttgct tccttgacag gatccccgcc ctcatggaag gtatccggga aaaagtatgg
     1081 aaggaatctt ccttctgtat atttgacacc ttcaatatca gagatcagac gaagtgtgct
     1141 tccgtttcca acgcttccta ccactgcgtc aagaccgatc gttgcaaact cctccatgaa
     1201 tggttctgtt ccgatccagt gatcccccaa aaacatcatt gcctctttgc cgcattcatg
     1261 tgtgatgtca accatctctt ttgcaagctt tgcaacttcc ctgcgctgga acgcctggaa
     1321 atccttgtat tctttgcttg gcacacgata ctggttatta tggtaaccct gatcgatgat
     1381 aaattccgga cggaatttat aaccgacctc tctctcaaac tgctctaaaa tatatggact
     1441 tacagaggaa gaataaccgt accagtcaac aaacttctct ctcttaagct catcaaatac
     1501 gagtgtgaac tgatggaaga acgttgtata acggatcacg ttcacatacg gatgctctgc
     1561 acagtatttg cgcagacgct ccatggaata cttatgtgtt ttcggctgtc tgacatcgaa
     1621 tgtgatctga tgttcaaaat ccttccagcc atttgtcaca gcattgtaca tatgaaccgg
     1681 atcccagatg atgtaagcta aaaagctgac tgtatattca tggaacggtt ctgtatcgtg
     1741 gatgcagaca cagccggttt cctcattgta ttcccattta tctgtggata ccacttcccc
     1801 tgtggagcgg tcgatgactt cccaccagcg ttttctgtca tctcttgtat ttacctgcat
     1861 cagttcatcc gaaattcctt tcattaaagg aatctgaagt tcgttaccgg ttgcagtgta
     1921 aaaattagtc atgatataac tctgctgcac ttcatccgga tttgcttttg cccacgcatt
     1981 atcttttctg gtggtataat aagttgcata tatttttgca ccggttttgg tcagttcctc
     2041 agggaactct gtaccgtcgc agtcacggat cgcatctgct ccccagcgtt tcattaactc
     2101 aattgtctcc ggaactacat ccaggtttgt tggaatcgtc actcttccac cgtgttcttt
     2161 attacccata atcttctcct ttatcctgta atttttgcat ttcctttttc taactctaaa
     2221 acaaaaaatc cttctgtttc ctctattatc tgcgttttct tgtctgtctc cagtctggct
     2281 ctttttgttg gaaatgtatt ttttattttt ataagcattt tctcaggtat cttcaatcgg
     2341 atttctgaca gataaccatt tttaattttt ccgcttacga gaataccacc ataactccga
     2401 aaaccattaa attctatccc ctcgttttcc cattgttttg gaattgctgg aaataaatgc
     2461 aaatatcccc gatattcctg taaaagcatc tcttgtaatg catcacaaaa tccaaataat
     2521 gcttccaacg taaaacgtct gtaatgaaag gttgaataac ctttttgctt gtaatcacca
     2581 ttcaggtgaa atccgttttc ttctacaaat ccatccgcaa attgtctcag tttttcataa
     2641 gcgcctgctc cattctctgc catagcatag agctgtgcac acattgcgaa cgaaaatcct
     2701 acccacattc cagttccgag tttctctatt tctgataagg cttttttata aagttccctg
     2761 tgttcttttg tatcataatg tatcaaatga agcggataca gacacattaa atgtgaaaaa
     2821 tgcctgtgtg actctttcaa acgttctact ctgttcaagc cgatatatcc atctataact
     2881 gcaatctcat ctaatttaga aagtatctct tcatatgctg ttttttcctt atttaatatt
     2941 tctgaatact cctgcaaccg cacaaacaag tatctgataa gtgcaagatc aaaattactg
     3001 tttgggatca aatatgcctc tggcgtatca tcatatattt ccggtgaggt ggagagtggc
     3061 aaatataatt tcccattctt ttcctctaaa agacccataa tggcctttcc aacttcataa
     3121 aaaaatggat atgccttctc ttttaaaaaa agaacatcac ctgtatacaa ataatactca
     3181 tcaaagctta gtgccaccca gatactcata gttggagaaa gtgcatattg tgaccagcca
     3241 cccattggtt ttccgtcaat cgttgacaca cccggaatga gcagaccatc cacaccataa
     3301 aactcgtttg caaactgttc aaaacgaggt tttaaattcc ataaataatc caaaaaaaac
     3361 ttctccctca gcaagcctgt ccgctttcaa atatgcctga taggacaact gtgtattcgt
     3421 atcatggtga taatctccgc gccatggcgg aatcttccca tcatccgcag tccagactcc
     3481 ttgcagtggc attggataat ttccttttct gctgcacgat gcaaataaat accacgaccg
     3541 gtaataggtt ttttccaaca gttcatcgtt gattttcagt gaagcctttt cccaatattt
     3601 ttttccacca ttttatatgc tcttccttta acttgtcgta tcctgtcctg gcagcttctt
     3661 ttaattcctc ttttgcgatc ctgtcaaagt catctccgtc tttgcttgtt ttaattgtaa
     3721 aataaatctc agcaaattcc ttttttaaga cggtatatgc gaacacacca taagagaatt
     3781 cactttttgt ttcctgtata taatacagaa agccatcttc cttttttatg tcagcctgtg
     3841 ggtaacccat tccgcatgtc ggagtaatct gtccgccatc cttaaacatt tccctttcat
     3901 tatgacagtc tgaagaaatg tattccggga tgcagagttc tgatctgaaa tcacctttta
     3961 ttcttgctgc tcctacaggc ttccatgcat ccatgaaaag ttcaatttct ccaccatcaa
     4021 aatgcatttc cccaatggca cttttcaaat caatttttgc atgtacgttt tggagttcac
     4081 acccataatc taacttaaaa tgtcctgcag agattttaga aggataagat aattcatcat
     4141 atattttttc aaaaagtctc tcccgttctt tccatgcttc ctctgtacga agtttagaca
     4201 gctttacaag atttttgtaa caaaatccag cttccaatgt attaggatgc tctctggtat
     4261 cccacagatc tattctgtcc actgccagat aaatggcatc ttcgccatac acaatacatc
     4321 ccagcctgcc atttccaagt ggtaacccca tatcccacga agtaatggca tgttcataac
     4381 aaatatcata tttacttaaa tccatactct tttcactttc tgactgttca gattttctta
     4441 tgattcttga taaacctcaa gtaatcttaa agccgcttct gttctcgatg aagtgatttt
     4501 tatgataagt tcctctgtct gtaccggatc aaacatgcaa atacgtttat gtcctacaac
     4561 tgtaaaatca gcaattttat tttttcccgc aaggatctct ccctgttcaa tatgttgtcc
     4621 caatggcaaa tattctccca gcacaactgc ggaaatattc ttaagctccg gaaaacgaag
     4681 tgtgatgact gcactcgcac tgtcctctga tgccaaccaa tatgtcccgt tgtctccatc
     4741 tgtaagaaat tctaccgaat gatctgtttg tacggtatcc gcttcaattt gtgccgtggc
     4801 agctatatta tgtgcaaatt tgtttttcaa catttcccca agttgtttca actgctcaca
     4861 atccgcttta gctatacgtc cgtgtttatc cggtggaata ttcagcaaca ggcttgcatt
     4921 tgcaccaacc gcatccagat aaatatggaa taactcctcc gctgtgcgta cctgtgcatc
     4981 ctcttcctca tgataaaacc agccggtgcg gatcgaagta tcaacttctg ccggatacca
     5041 gaccagtgtt tccgcctgtt ttattgcttc ccggctgccc agatcctcat cctgcgagtc
     5101 gaattttctg gaaaatgttc cgtcatctga cttttgcgac ttttccgagg ttcgttctgc
     5161 atcacggagt tctgccggaa caacactcca ctcactcttc ctgcaatgtc ctgcctcatt
     5221 tccacaccat cttacatccg gtccacatat attaattact gcctccggct gtaagtttcg
     5281 tattacactg tagtacctct cccagtcata gacttgtttt ttccgttcgg tccttcaccg
     5341 catgcaccat caaaccaaaa acaaaatata tcaccgtaat tgcttgcgag ttctgtcaac
     5401 tggttcacaa aataatcatc atatgctgtt ccgcttccat aacatgactc atgccgatcc
     5461 catggtgata agtacacccc gaattttatt ccaccgcgtc tgcacgcatc tgcaacttcg
     5521 cgcaccacat ccccctgtcc atttttccat ggactgtttt taacactata ttctgtatag
     5581 gcacttggcc acaggcaaaa accgtcatgg tgtttgcacg tcaacagcag tcctctcatc
     5641 cctgctgact taacagccgc tacccattga tctgcatcaa acgcatctgg tgcaaaaagt
     5701 ctcggggaat ctgttccatc tccccactca cgaccggtaa aagtattcat accaaaatgc
     5761 gtaaatgcat aaaattcaag ctgctgccat gcaagctggc gcagacttgg tgcaatgcca
     5821 gccgcataat aaatctgttc ttcgggtgtc ctcatctttt cctccttctc ctgtatctgc
     5881 tttttttatt ccagataaga aattaacctt tcagacctcc gacattcatt ccctgaatta
     5941 actgcttctg tcctatcagg aaaataataa tggtcgggat taacgctaat ataagtgctg
     6001 caaacaatgc tccccagtct gtagcataac gctgaacctc atacagattg gcaagtccga
     6061 ccggaagtgt ctgcttttcc gggtcagtta acataacaag tgcaaccgga tattcgttcc
     6121 atgcagccat cgctgaaatc atacacactg tcacaattcc cggctttgcc atcggcataa
     6181 ttacttttat caggatacgg aacggtccac agccatcaat cattgctgct tcctcataat
     6241 ccctcggaat agaccttaaa aagccggaca aaacaaatat ggcaaacgga aactgcattg
     6301 ttgcatacaa aacagccagt gccacacggt tattgagtaa atgcaatgca ttcatctgta
     6361 aaaacagcgg tatcataata aaggttgcct gaataaaaat agctgccata taaatattta
     6421 acatcagcct tgagccaaaa aatttatacc gcaccaggca ataggcacac ggaacagcac
     6481 ataccatgat gacgcacaat gtaataagta caatcagcac ggaatttccg acattgctta
     6541 aaagatttga tttttcaatt gcacgcgcat agttatccca tgccagactt ttgggaagtg
     6601 aaaatgcatt tgtaagaaat tcattattcg ttttaaacga tgaataaaca ttccaaagca
     6661 atggataaat cataatcact gtcaccaaaa tcataaaaat gcggacgacc caccgcaatg
     6721 cggctgcctg gcgtcggctc tgctcatttg tcttcatatt tcctaccccc ctttaagact
     6781 cactgtttgt aagcttacgt gaaaccattg acaacgcaat cgaaattatc aatgtaaata
     6841 ctgtaattgc cattgcatat ccgaagttac cgtttataaa tccctgggta tacatgtact
     6901 ggagcaatac ggaggatgca ccgtttggtc ctccaccggt cataaccttg gataaggtaa
     6961 agcttaaatt tatcgttccc gaaagagcca atacaaacgt aatacctata atgtctttta
     7021 ttaacggcag cgtaattgaa aacattttac ggacaggacc tgccccgtca attgttgctg
     7081 cttcataaat ctcactggaa ataccatcca ttgccgcaat atgcattacc atatagtaac
     7141 cggtcgcctg ccagattaaa gtgactgcaa tacaccagag tgctgtgctt ccatcaccca
     7201 gccatgattt tgcccaggca gacaaaccaa ctccatttaa aaagctattt aaaataccca
     7261 tggtcggatg aaaaacaaat gaccagataa ttcctacgac tgtaagtgat ataatgtttg
     7321 gaaaatagaa tactgtccgg tacagaccac gttccttcaa atcagactgt gaaataataa
     7381 acgcaagtac cagtgcaatc gcaattgtaa ttattgggac aaccgccata agctttagtg
     7441 tattttttaa tgcaaggata aaatattcgt cccggaacat atatttgtaa ttctccagaa
     7501 aaacaaactt actgtttaat ccaagagaag ttgcattcgt taatgataat aaaaacgccc
     7561 gtatagtcgg aataattgta aaaatcagtg tcagtaaaaa ggctggtaaa acacatatac
     7621 agataaaacc taccggcagc ttctgccctt tctttttttt cttttccggc agcttgcagt
     7681 ttcatttaat tacccctttc gaaaaaaaat agcgccatgc cacacaatgc ggcatggcgc
     7741 ctcataagtc tacagactta cttgattatt gcgcagtttc tgaaacctct ttaaaggaat
     7801 tttctacttt ctgagcccac tcttctgcac tcattttacc tgtcataaca tctgacaata
     7861 cgttaaatac atcatcattc ggaactacct tgcatccttc tggtaatgct gcaaaaccaa
     7921 ataccatgga tgttccatgc tcataaatct cattcatatt atagataccg tcagaaacaa
     7981 gtcccttgga taactcagtt gcatctttta atgcgtaaat accatttgcc ttttctgcaa
     8041 acaacttcac agactcttct gtatacagga aacgtaaaaa ctcttttgcc agctcagggt
     8101 tctctgcctt tgcaggaata ctaaactgct ctacacttgt cataacatag gcttcatccc
     8161 catcttttaa aactggggct gtccagagtc caaactcgaa accatccgct ctcggagcgt
     8221 ctgccatctc attttccatc cagttaccat ttggaataaa caaacatttg ttcatcatca
     8281 tttctgtctg ggactgtgta tggttcaatg caactgtacc ctccagcaaa tatcctccgg
     8341 tgccgatctt tgctatattt tcaagaactt ccatcgcttc tggttttgag aaagaacctt
     8401 ccacataatt agaaatgtct ttgatattat ctatccctgt agcagaagct aaggccggcc
     8461 acaataaaga ctctacatat gacggataaa ttcctgcata agtcatcagt gcatatccat
     8521 cttcttttgc ctggtcaccg agagcaaaga attcgtccca tgtcgtcggg agttcataat
     8581 tcatttcctc aaacagagtc ttattgtata caagtcccat tgggctgctg ttaaatggcg
     8641 ccagataaat ctttccatca gcatacggct gacattttgc tgtctcaaga atacccgtat
     8701 ttacctgatc ttttaatggt gtctcatcat caatgccagg tccttcaaac acatctgtca
     8761 aatccaataa tgcatgttcc ttaatcatag acgagataag acctgtagaa tcattgtcgt
     8821 tcataacaat aaaatccggt acatttccgg caacaatttg tggtctgatg acatcaccaa
     8881 ttgatgggct gatctgcatg tcaacctcaa ctcccggata ggctgcttca aacttctcga
     8941 ctatttcatt ccagtaatcc ggaccataac ctccttcaaa taccgcaata tttaatttct
     9001 tgttctcaaa ttctgccgca ttgtctgctg ttccattctt ctccgttttt tctgtgccta
     9061 ctgtgttttc tgcgctgctg ttgtctgtgt ttgcggatgt atttgcattt cccccgcatc
     9121 ctgccagtgt tgctgcacac atgcttgcaa caagtagcgt actaatcgct tttttcattt
     9181 taatttcctc ctgattttta attttctgga aaactttttt gtctcccttg gaatgatttc
     9241 attatagctg taacaggtgg cagattgaat ggacacaatt tacaaaaagc tatacaatat
     9301 tgactttttc gactgacact gttagtatta atgaacagct aaaaataaag tattggaaaa
     9361 gaggaaactt tgaaattaac aaaaacacgc cattgcgtaa aacagacaaa tcttttaaga
     9421 accattaaaa tcagaaaccg gcttttatgc atttttcttt ttatttccct tgttccggtt
     9481 acttttatcg gcttttatgc atacacagta tacacccagt caatcaatga taagctggaa
     9541 cgttccaatg aacaggctct gtatctttta aatcagaatt ttattaccga gctcaacata
     9601 ttccgtatgt atattgacac aatttccgtc agcgatgaat gccagcagat cctttccaaa
     9661 tcatgtgata ccaatttcac attaaatgaa caggatgtac aggcactcaa cgatttccgc
     9721 agccgtgttc cattcccatc cattcacctg aaaaatctgc gtattctcga ccgcaatcga
     9781 aatatcgtat atgatttagg atatgatgat atagatgccg aacgtttttc ccagattgta
     9841 gaagaaattg atgaaacctc ccctcatgac tcccttcaat atatccacac ctatcgaagc
     9901 agtgacaaaa tcattatcgg ccgtaaaatt tacagcagta cacgtctgag tgagcatatt
     9961 ggttacatcc ttatttatct tgatgaaacc tttttcagca atacactttt tacaaacgtc
    10021 tcctttggag atgagtccaa tattatgctt gtgcgcggtg acggctatat catttcctcc
    10081 cagaagcgtt ccgtacttgg cgcactgtta gacgatgccc tgcttcagca ggtgaaatta
    10141 aataaaaact cccttgccga aaccttttac acagaatatg agggtgaaaa gcttgttatt
    10201 atctctgtgt ataacagtga atttaataac tacctcatgg ctaccttccc ctatcgctac
    10261 attaccgatg agacgagcag gattaatcaa agactgcttc tccttgcagc cattttaatt
    10321 gcgctctgcc tgtgtcttac gctcattgta tacacaagta ttatgcagcc aattcaccag
    10381 attgtcacaa aatgcaatga tatttcctat gaggacttaa acacagccat caacgataca
    10441 agccccgacg aattaggttt tcttgcccgg acaatcgacc agatgcttca acgcattcac
    10501 atgttccata tcgaacaggc tcagaatgag gagcagaaaa ggcacctgga attaagagtt
    10561 ctgcaatacc agattaacac ccattttctg tttaacacct taaactcgct gcgtatcgtt
    10621 gcacagatga acgatgtacc tattttagaa cagggtatct cctcccttac ttttttattg
    10681 cagcagacac tggtcaaaaa acaggagcgg atacctcttt cccttgagat tgaaaactta
    10741 aaccactatt ttacggtgca gagtatccgc tatgccggaa tgttcgatgt gaaataccat
    10801 ttggaaaatg atactctcgc ctgtgaaatc ccacgctttg cattacagcc gctcgctgaa
    10861 aatgcgatta tacatgggac cgccaatgca gctattccaa ttataatttc ggtggaaagc
    10921 catttttctg acaataaaac acttgaaatc atccttcgtg acaacggatg cggatttgac
    10981 caggacgagg taaaacagac agacaaaaaa tgtggctcgg gtatcggcgt agacaatgta
    11041 aaccaacgga ttaaattaca ttacggcgct tcgtacggcc ttaagctgga aagccatccg
    11101 ggagaaggca ctgtctgcta tctgacactt ccgcacatac tttataagga ggaaaattaa
    11161 aatgagttta caaattttac ttgtagatga cgaacctgcc atcaaaatcg gttttcgtca
    11221 gttaacggac tggtccaaaa ctccttatac tctttgtgga acagccggaa atggaaagga
    11281 agcacttgcc tatcttgaaa agaacccggt cgatattatc ataaccgatt taaaaatgtc
    11341 cgtaatggac ggtatcggtc ttattcacgc cttaaagcag aataattcgg aaattcctat
    11401 cattgtgctc agcagctatt cggattttga gcttgtccgg gaagcactga ctgccggggc
    11461 agccgattac atattaaaag ccaacatttc cgctgacagc ctgatagcgc atctcgataa
    11521 ggtggccgga aatcttttaa acagacagaa agaccgtgcg gctgcccttt tgcaaaagca
    11581 gcagttagag gaacagaata cacagatttt aatgaatgat attcgtaatt tctttttaga
    11641 tgaaacaatt actaccgaag aacttttaaa ggaaacatcc gaccttgcgt ttttttctgt
    11701 tccgtgtatc gtgctcacat tattttttca cgaagatatg aaacgggaaa aattaaaacg
    11761 tgttgcacca aatattcaga ccctgctgac agaaacgctc gctttggcag cttcccctgt
    11821 cagcattatg atgcaccaca atgagcttgc attttttctc ccttacagcg acaccttaaa
    11881 atacaatatc tcatcaaaaa cacaggttct caatcggcag attgccacct atttcggtgt
    11941 tctccctatt ttgtgctact ctgcaccggc tgccggtgca gccgaatgcc ggaatgcata
    12001 tttttcctgt ataaatgcaa ggagaattac tttttatgag aagaaccgtt ccattatttt
    12061 tacaaaggat attcgttttg tttttgaaat ttccgcagaa gaaatccagg aaacaatgaa
    12121 ttccgtttta aactttgtgc agaccggaag ccgtgaaaat ctgtttggat atgtccgaaa
    12181 tctcctggca gaatggtctg cccttccgct ggaacctttt catctgtgca tgaattgcgt
    12241 ccatattttt gaaggtgtcg cattgtccgg caaatctgga aaactgcatg cacaaattca
    12301 tgattaccag aagaaaattt cgcagtccac aagcttggca gaattaaagg ttacactttg
    12361 tgatgcgctt ttacttttac tggaaagcaa tgaaaataat tatgaaaatt acaaaaaaga
    12421 aattcaggtt gtgatgcggt atgtgaacgt acactacaag gaacatatca ccctcgacca
    12481 aattgctgag gaggcaaacc tgaacaaaag ctatctctgc cgccttttca aaaaagaata
    12541 cggtgacagt gtctttaatt atctgaatat gatacggatg gaaaaagctg ccgagcttct
    12601 gcggagcaat cccggacttt atgtgcagga ggcagccgca gaggtcggaa ttacagaacc
    12661 tttttacttt accaggcggt tcaaagaata ttttggcatc tcgccaaggg aatatatcct
    12721 gcgggtttca gacaatgacc attccccgga ggcataacct ttcttcctct gtccctgcac
    12781 gattaaaaaa ccagcacact gtgatttaac tcatctgtgt gccggttttc cttttcttta
    12841 tcttctgtaa agctcaaatt ctgcaatgct cgggtctgtc tgtccggcac tgtttgccga
    12901 agtatccgcc cgcaacgcag taattaccag ccttattttc tgtgctgtgg tatcctcaaa
    12961 agcaaattcc ttcctttctc cgacttctcc tgtattctca aatattgtct gatatgtggt
    13021 tccatcccac gcctgaagct ggaagctttc aattcgcggc gttgcccagt ttgcaacaat
    13081 attttccgtc attgccattg tgttaaatgt cacatcactg cccaggttaa attctatctc
    13141 aatcggtaat tctgaattgg cagatgccca gcgtgtatcc atttttccgt cattaagcca
    13201 tgatacatca aaatcattat gacagttatt ggttataact tctttgttta aaaccagatt
    13261 gacctttttg gaagcctgtt tattataata aagctccagt tctttcaggc tcgggtctgt
    13321 ctgtcctttt ccgtgcaatg tcgtatctgc cttaagccct gtaattacaa aacgcagttt
    13381 tgtcgttgta acttctggaa aaacaaactc tgcagactcc ccaattgttt cactgctctc
    13441 ataaaacttc tcaaactccg ttccgttcca tttttgcagt tcaaacttgg caattcgcgc
    13501 agatgcccat ccggaaacga tattttcttt tgctataagc tcattaaagg ttgtctcctc
    13561 cccaaaatca agctccagcc aaatcggaag ggtggagtcg gcagatgccc atcttgtcgt
    13621 atcatctcca tccactacat tacacgcatc aaacgataca tggaaattat ttgcactcgc
    13681 agaagctttg accgcaagat taaccggtgg tgcattatat tctccttccg gtacttcata
    13741 tacaccaata tccggtgcat ccccgtaata taactgattt ccgaaaaagt ccatcgttcc
    13801 catctgtggt acataaatcc ccgcatcaac taacggagag tccttcccaa ttttataacc
    13861 gtcccaaatg gtggcaccgc tgagaattcc ctgttcattg cgctccggtt tttgtcccgg
    13921 atttaccatt ttcgggttct cggtaacttt atatgcatct gccggttcat atttcgaatg
    13981 tattccgctc gcctcataaa aacaattgtt actgaatgtc accgctccaa gatttccgag
    14041 atatctggca gtatcatgcc acgttgtcgt agttgtggtg cttttattat agaatacatt
    14101 attgtaaaag tatgtctgtg atttaaatgg gtcccgatgc ataaacttcg ttctttcccc
    14161 atcatatata ataacattat ttaaaaaata ggttggtgtt tcacaggctg tcagaaaata
    14221 tttaatgatg taatcgccgc cgtcatcact gatattataa cggataatat cattattatt
    14281 ttttcccata tacagcatcc agccacacgg attgttatgt gaataattaa actgatatac
    14341 aacatctttc agacctgagt ccatatcata agggcttcca tctgcatttg ttgacggtcc
    14401 gttgtatacc tcattaaact gaaaaactgc attttcacat ttccatggat aaagtgcaac
    14461 cgtcggccgg aaattcggat aacgtttcaa aaatccatct acaacattgt actccacaac
    14521 tgcgtccttc gcatcacaca agtcaattgc tccctgcgca atgtcctcaa aatagttgtg
    14581 tccgatatac acgttcgtca tccacatatt gttggcatca atcccatcct gatagtttcc
    14641 cttaacggtt gtaacatatc cggtaactcc cagaaggtcc accttacgga ttgtattgta
    14701 tgcaatacgg agatcattaa agctgctgga aggtctcaat gagcttccaa ccacgttaaa
    14761 tataattcca ccagtaaatg tatcattcca gtcatttggt ccgtctacat catgtacata
    14821 acagttctca atgtaaatat ggtccataat tccgtcatca tcatcctcta actgatcaca
    14881 atcgacaatc agaagtattc cgtttcttgt catattttta ctcgaccagc tattgtcgcc
    14941 cttcggtctg gaaaggtcaa tatcctcatc aaagtcatcg tcatttgtaa tttccagatt
    15001 tctgatttcc cagtactcct gatttctcag atggactgct ccagaatagt ttaatccacg
    15061 gtcaattccc ataccgttta taataggttt ctcctcaccg ccgtacttgt caataataat
    15121 cggcgctcct tccacaccgg agcctttcgg ccataaccat tccccattcc acacactgcc
    15181 ggattttaac agaatttggt cgcccggcaa aaatgtcgta tcagtgactt tattcagact
    15241 tttccatggt gcatctatgc ttgtgccact gttagagtca tctccatttt ctgcatcaac
    15301 ataataggtt gtccctgcat tacctgtcgt ttcctgtgca tttacacaaa caggcatgct
    15361 tcctgtcacc atacctgcaa caattactgc cgccagcaat gaactaatct ttttttatac
    15421 attcttcttc tcctaattcc atttaatcgt atcgtaaact ctgtctacga ctgttactga
    15481 aagttcttcc tctctgtctg tcagatatct ctgaaactgc tctgtcataa tcatatcctc
    15541 cagacggttt cttacctcat cataagagag tccgctgccc tcctttctgc ctaaataccg
    15601 gactgcataa taacctatgg agtcatcata ataaacatct gatatctccc cggcattcaa
    15661 tccatagact gcttccaaat aaatactgtt gctgcgcgag tcccctttat ttgacatctc
    15721 tcctatcgca agctctgttt cgtcatattg cccgatgcgt tctttttcag actgtattct
    15781 gccgttaacc tcaatttctt tttttatctg tcttaacgtg ctctccccat tgccgtccgc
    15841 tgcatccggc actgaataaa ccaaaagact gatttcatct ccctgcgaaa acagttcttt
    15901 gtggctttca taatactgcc ttgtctcact ctcctgtaat ctgttatcca ctttatattg
    15961 ttcaaacatt tccagtttta ttttactaat atagtaagaa taataatctg aaaaactcat
    16021 ctcaaccggt ccatagacaa tttcgttact ctcaactgca ttttttctcg cagctacaaa
    16081 ctctttccag tcttttcgaa tatcagagta ggatacactc tctgccatcc cggcttcctt
    16141 tgccagtagc agaatatttt ttgtctccac aatatttttc aatgcacgtt cacgcgcata
    16201 ttcctccggc gttattccat caaactgcgt attccgaaaa gaagacacag aggtatccgc
    16261 attgtatttc cccgcaaaat atgcataaga tgcacttttt tcctccgata caaaaaattc
    16321 tgcctcctct ttggaaatct taatattttc tacataaagt gccggagaag aaataagcag
    16381 acttattcct gtaatgctga atgctgctaa aagaacaatt cctataacaa aataaaaata
    16441 tcgtctcttt cccat
//
