LOCUS       CP002160               19148 bp    DNA     linear   BCT 08-JAN-2014
DEFINITION  Clostridium cellulovorans 743B, complete genome.
ACCESSION   CP002160
VERSION     CP002160.1
DBLINK      BioProject: PRJNA32609
            BioSample: SAMN00002614
KEYWORDS    GSC:MIGS:2.1.
SOURCE      Clostridium cellulovorans 743B
  ORGANISM  Clostridium cellulovorans 743B
            Bacteria; Firmicutes; Clostridia; Clostridiales; Clostridiaceae;
            Clostridium.
REFERENCE   1  (bases 1 to 19148)
  AUTHORS   Lucas,S., Copeland,A., Lapidus,A., Cheng,J.-F., Bruce,D.,
            Goodwin,L., Pitluck,S., Chertkov,O., Detter,J.C., Han,C., Tapia,R.,
            Land,M., Hauser,L., Chang,Y.-J., Jeffries,C., Kyrpides,N.,
            Ivanova,N., Mikhailova,N., Hemme,C.L. and Woyke,T.
  CONSRTM   US DOE Joint Genome Institute
  TITLE     Complete sequence of Clostridium cellulovorans 743B
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 19148)
  AUTHORS   Lucas,S., Copeland,A., Lapidus,A., Cheng,J.-F., Bruce,D.,
            Goodwin,L., Pitluck,S., Chertkov,O., Detter,J.C., Han,C., Tapia,R.,
            Land,M., Hauser,L., Chang,Y.-J., Jeffries,C., Kyrpides,N.,
            Ivanova,N., Mikhailova,N., Hemme,C.L. and Woyke,T.
  CONSRTM   US DOE Joint Genome Institute
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2010) US DOE Joint Genome Institute, 2800 Mitchell
            Drive B310, Walnut Creek, CA 94598-1698, USA
COMMENT     ##MIGS-Data-START##
            investigation_type       :: bacteria_archaea
            project_name :: Clostridium cellulovorans 743B, ATCC 35296
            collection_date          :: Missing
            lat_lon                  :: Missing
            depth                    :: Missing
            alt_elev                 :: Missing
            country                  :: Missing
            environment              :: Soil
            num_replicons            :: 1
            ref_biomaterial          :: ATCC 35296
            biotic_relationship      :: Free living
            trophic_level            :: Chemoorganotroph
            rel_to_oxygen            :: Anaerobe
            isol_growth_condt        :: Missing
            sequencing_meth          :: WGS
            assembly                 :: Newbler v. 2.3 (pre-release)
            finishing_strategy       :: Finished
            Sequencing Depth         :: 30x
            GOLD Stamp ID            :: Gi02570
            Type Strain              :: Yes
            Greengenes ID            :: 16224
            Gene Calling Method      :: Prodigal
            Isolation Site           :: cellulose digester
            Source of Isolate        :: ATCC 35296
            Cell Shape               :: Rod-shaped
            Motility                 :: Nonmotile
            Sporulation              :: Sporulating
            Temperature Range        :: Mesophile
            Gram Staining            :: Gram-
            Diseases                 :: None
            ##MIGS-Data-END##
            ##Genome-Assembly-Data-START##
            Finishing Goal           :: Finished
            Current Finishing Status :: Finished
            Assembly Method          :: Newbler v. 2.3
            Genome Coverage          :: 30x
            Sequencing Technology    :: 454/Illumina
            ##Genome-Assembly-Data-END##
            URL -- http://www.jgi.doe.gov
            JGI Project ID: 4085037
            Source DNA and organism available from Christopher L. Hemme
            (hemmecl@ou.edu)
            Contacts: Christopher L. Hemme (hemmecl@ou.edu)
            Tanja Woyke (microbe@cuba.jgi-psf.org)
            Annotation done by JGI-ORNL and JGI-PGF
            Finishing done by JGI-LANL
            The JGI and collaborators endorse the principles for the
            distribution and use of large scale sequencing data adopted by the
            larger genome sequencing community and urge users of this data to
            follow them. it is our intention to publish the work of this
            project in a timely fashion and we welcome collaborative
            interaction on the project and analysis.
            (http://www.genome.gov/page.cfm?pageID=10506376).
FEATURES             Location/Qualifiers
     source          1..19148
                     /organism="Clostridium cellulovorans 743B"
                     /mol_type="genomic DNA"
                     /strain="743B"
                     /type_material="type strain of Clostridium cellulovorans"
                     /db_xref="taxon:573061"
     gene            complement(1..1407)
                     /locus_tag="Clocel_2249"
     CDS             complement(1..1407)
                     /locus_tag="Clocel_2249"
                     /EC_number="5.3.1.12"
                     /inference="protein motif:PRIAM:5.3.1.12"
                     /note="KEGG: cpe:CPE0152 glucuronate isomerase; PFAM:
                     Glucuronate isomerase"
                     /codon_start=1
                     /transl_table=11
                     /product="Glucuronate isomerase"
                     /protein_id="ADL51988.1"
                     /db_xref="InterPro:IPR003766"
                     /translation="MKEFMGEDFLLSTETAKTLYNEYAKDMPIFDYHCHLIPEQIATDK
                     KYNNITEIWLYGDHYKWRAMRSYGVDEKYITGDASDFQKFKAFASVMPYLIGNPIYHWS
                     HLELRRYFGVTEVLSEKNAEEIWNKCNEVIKSSGFSAKSIIMNSNVKYIGTTDDPADSL
                     EFHQEIASDKNFTCEVRPSWRPDKAVKIGNQDFAEYIKLLGATENTTITSYAKLLDVLK
                     KRLKFFVENGCTITDHAMDRVYFRETTEEEVDSIFKKALAGQALSQEAIEKYVTLTMIK
                     LSEMYHELGMILQLHIGALRNNNSRMFKKLGPDIGFDSIDDGEIAQPLSKLLDALESQD
                     KLPKTILYCLNPKDNEVLATMLGNFQGGGIASKIQFGSGWWFLDQKDGMIKQLTALSQL
                     GLVSKFVGMLTDSRSFLSYTRHEYFRRILCNYLGELVENGEYPADMEVLGQVVRDICYN
                     NAVIYFKNQK"
     gene            complement(1421..2908)
                     /locus_tag="Clocel_2250"
     CDS             complement(1421..2908)
                     /locus_tag="Clocel_2250"
                     /EC_number="4.2.1.7"
                     /inference="protein motif:PRIAM:4.2.1.7"
                     /note="PFAM: D-galactarate dehydratase/Altronate hydrolase
                     domain protein; SAF domain protein; KEGG: bcl:ABC0442
                     altronate hydrolase; SMART: SAF domain protein"
                     /codon_start=1
                     /transl_table=11
                     /product="Altronate dehydratase"
                     /protein_id="ADL51989.1"
                     /db_xref="InterPro:IPR007392"
                     /db_xref="InterPro:IPR013974"
                     /translation="MHRIVKINHDDDVVVLLEDSTIGEVIVADEQEIKLLNDIPKGHKV
                     AIKNIEKGQDVLKYGYSIGKAKEDIKVGEWIHSHNLGTGLGEILEYNFKGAMKQTVKEN
                     SAITFKGYVRDNGEVGIRNEIWIINTVGCINKTCANLAREGNKLINDKVDGVYHFEHPF
                     GCSQLDSDLENTRKILANLVNHPNAAGVLVVALGCENNTLESFKELLEPINEERVKFLR
                     VQDVEDEIEEGKKLLGELIQYASKFEREHVNISKLKIGLKCGGSDAFSGVTANPLLGRI
                     SNEITSLGGTAIQTEVPEMFGAETILFDRSINKEIFDKSVELINDFKEYFMRYNQVIYE
                     NPSPGNKKGGITTLEEKSLGCVQKSGKAVVTDVLQYGDRATKTGLNLISGPGNDQIAVT
                     VLAAAGAHIVLFTTGRGTPYGGSVPTLKISTNTDLYNRKKNWIDFNAGELIGSNNPEKI
                     DEEFLKLIIDTASGDYRAKNEVNDYREIAILKDGVTL"
     gene            complement(2901..4370)
                     /locus_tag="Clocel_2251"
     CDS             complement(2901..4370)
                     /locus_tag="Clocel_2251"
                     /inference="protein motif:PFAM:PF08125"
                     /note="PFAM: Mannitol dehydrogenase domain; Mannitol
                     dehydrogenase rossman domain; KEGG: gym:GYMC10_4122
                     mannitol dehydrogenase domain protein"
                     /codon_start=1
                     /transl_table=11
                     /product="Mannitol dehydrogenase domain"
                     /protein_id="ADL51990.1"
                     /db_xref="GO:0016491"
                     /db_xref="GO:0050662"
                     /db_xref="InterPro:IPR000669"
                     /db_xref="InterPro:IPR013118"
                     /db_xref="InterPro:IPR013131"
                     /translation="MLKKLSVECLNEKQRSIYDKVVKSPIKVMQIGEGNFLTSFFDWML
                     YKAIEAGKYEGSVALTCPLDFDKKINILKEQDMLYTVTQRGFKDNVEVDESDIISVFSK
                     VFNYNVDWNSFMEIAELESLEVIISNTTEAGLAYKEVELDKVSVDGLYPGKLTAFLMHR
                     FENIKDKTKKLLIFPCELLDDNGKVLEEMVKKHAESFGTSDEFKTWVNESCVFLNNLVD
                     RIVPGFPRENTEAYFEKLGYIDEAASVCEPFFLWGIEGSEEYDKILPLKSAGLNVKWAD
                     SLYDIHLLKVSILNGSHTLITPLGILKGFERVDELVEDPEEKAFLNEALQNEIIPSLKN
                     EDAEGYAKTILQRFRNPHLKHKLESISMNSVSKFVNRDLPTVKAYIEDNNSLPKNMVIG
                     LAGLLRFYQIEKKEDKYIGHNFKGKEYPVFDVINVLDFMCNMNKEYSIKNQNYVKAILS
                     NTELWGEDLTKIEGLTVAVSEALESLERKYA"
     gene            complement(4426..5256)
                     /locus_tag="Clocel_2252"
     CDS             complement(4426..5256)
                     /locus_tag="Clocel_2252"
                     /inference="protein motif:PFAM:PF01522"
                     /note="PFAM: polysaccharide deacetylase; KEGG: cac:CAC0358
                     xylanase/chitin deacetylase"
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase"
                     /protein_id="ADL51991.1"
                     /db_xref="GO:0016597"
                     /db_xref="InterPro:IPR002509"
                     /translation="MAKIYRCFPDGKFKVLTMSYDDGKITDRRLVNLFNDYGIKGTFHL
                     NSGYMEQNDPVLTLPYEKRIPKEEVKELYKGHEVACHTVTHPTISRCPMPQVIEQILED
                     RKVLESIVDYTVRGFSYPNGSYNNEIKDMLRHVGIEYSRIVGNSDNFKMPTDYYQWQST
                     CHHLHNLLEHADEFIGLSKKQYLYMFYVWGHSYEFEKDNNWEVIEEFCRRIGHRDDIWY
                     ATNIEIVDYLKVCDNLKFAADGSFVYNPSVASAWVVINDDNIVEIPGGAKVNLK"
     gene            complement(5891..6586)
                     /locus_tag="Clocel_2253"
     CDS             complement(5891..6586)
                     /locus_tag="Clocel_2253"
                     /inference="protein motif:PFAM:PF00392"
                     /note="KEGG: cpe:CPE0148 transcriptional regulator; PFAM:
                     regulatory protein GntR HTH; GntR domain protein; SMART:
                     regulatory protein GntR HTH"
                     /codon_start=1
                     /transl_table=11
                     /product="DBD-Pfam|GntR,DBD-SUPERFAMILY|0039384"
                     /protein_id="ADL51992.1"
                     /db_xref="GO:0003700"
                     /db_xref="InterPro:IPR000524"
                     /db_xref="InterPro:IPR011711"
                     /translation="MVLYDKNENESGKDYAYRVLKENIMSLELKPGELLSEIELSEKLG
                     ISRTPIREVLMKLKSEHLIEVKPQSGTYVSLIDLDLVQEARFMRFALEEKVLKSACEEF
                     NEELFVELDKNLYAQQILADMEGGEKEFHKLDNRFHELFFLGVNKVNVWQSILNISTHY
                     NRMRLLSQAEDPKKDVVEQHAEFIKVIKEKHIDKVESLINDHMRYTKKSWEHLLEEKNE
                     SHNFFKINK"
     gene            complement(6682..8214)
                     /locus_tag="Clocel_2254"
     CDS             complement(6682..8214)
                     /locus_tag="Clocel_2254"
                     /inference="protein motif:PFAM:PF00295"
                     /note="PFAM: glycoside hydrolase family 28; KEGG:
                     bld:BLi03511 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="GH28"
                     /protein_id="ADL51993.1"
                     /db_xref="GO:0004650"
                     /db_xref="InterPro:IPR000743"
                     /db_xref="InterPro:IPR006626"
                     /translation="MEQNKFQWNQKLYDFIEEKVNKNMPMIGNLMEYRITDERYTKLIK
                     EINEEYFTHVDGTYKGTKSELKKDKEYIAKALIRNVQEVTYYGDAIQRAIDEANSNKDG
                     GKVIIPGSENPEAPNVYYTGAITLKSNVILEIQKNAILRFVRNKTNEFYPLVYTRWEGV
                     EMMNFSPFIYSYEAENIAIVGEGVLDGNADEFNWMPWKFGYFKEEDQQIQRERLFELGQ
                     KNADVRTERIFGDDVSTIRPPFIQPYKSKNILIKDVKIINSPFWEINPVLCENIKVDNI
                     KVGTNLYNNDGVDPESCKDMIIENCYFLTGDDCIAIKSGRNNEGRNIGVPTENVIIRYN
                     EFKDGHGGITIGSEISGGVNDIFAHDNYFDSKELDYPIRFKTNAERGGKLENIYVKNST
                     VNKSKIAVIHADFFYEEGTNGDHKPILRNITLENIKTVEGGSIDAKNALYIKGFEHAPI
                     ENIVIEDAILNGVNGEAILQNVKNITFKNVSINGKKLADKTFHVNNEFQEII"
     gene            complement(8462..9970)
                     /locus_tag="Clocel_2255"
     CDS             complement(8462..9970)
                     /locus_tag="Clocel_2255"
                     /inference="protein motif:PFAM:PF07690"
                     /note="PFAM: major facilitator superfamily MFS_1; KEGG:
                     cac:CAC0357 Na:galactoside symporter family permease"
                     /codon_start=1
                     /transl_table=11
                     /product="gnl|TC-DB|Q93KC2|2.A.2.5.1"
                     /protein_id="ADL51994.1"
                     /db_xref="InterPro:IPR011701"
                     /translation="MKKKISIKHMIGYASINFLGSGSQNIVQLYLLIFYTSLCNLSVLQ
                     AGSIFAGTRFLDAALNPIMGFITDNFGKTRLGRRFGRRRFFILLGAPLSLLVFPMMWTV
                     GHSYAYYFGINMIWEMVFTMVIVSTIALPAEMAQTAADKTKLVAAKSYCGTIANMISSF
                     IPAQLFVMYGENNPDAFHLTGIVYAVILALSLVVVYSLTFERAPEDIVYSNEAHGIGQV
                     LKKLLLDISSTLKVKSFRIHTIMMLLIGIYKNLANSVFTYFVVYCLVLSKSVTGYISAF
                     STLISLATLTLFVALAYKFGGPKTLRVATSLVVLAALGLFGLTFLKGTSLIIPALVAVQ
                     IINTVGKGGADYIPVFQLPFMADIDEAVTGTRREGIFSGVNGAMSKIAYGVESLLLGFG
                     LQAFGFVKGAKEQPQLAIVGVVIFATVVPTVLLITTVIVSRKLKLNKETHKILVDEVNR
                     VKAGGSKADVTPEAREAIEELTGFAYENCFGNNNVGYHSKAANA"
     gene            complement(10054..11142)
                     /locus_tag="Clocel_2256"
     CDS             complement(10054..11142)
                     /locus_tag="Clocel_2256"
                     /inference="protein motif:PFAM:PF07470"
                     /note="PFAM: glycosyl hydrolase family 88; KEGG:
                     cac:CAC0359 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="GH105"
                     /protein_id="ADL51995.1"
                     /db_xref="InterPro:IPR010905"
                     /translation="MRDYAKWMADSVIARNTDLTSYWAYEFGLTLDGIAEVWKQTQDEK
                     YFKYVKDAMDTFIGEDGSIRGYRVDEYNIDHLNNGKIVLTLYQATKEEKYKKALELLRT
                     QINNHPRTREGVFWHKEIYPEQIWLDGLYMGATFYAKYVNEFGDVAEFDDIAKQFVIAK
                     QHLIDEKTGLLYHAYDDARVQPWANKETGLSAHFWSRSMGWYVMALVDTLEVLPKDNKH
                     RAEMLEIFQNTVDALIKVADKDSHVWYQVLDQGDRKGNYLEASGSSMIAYSILKGVRIG
                     LLREDLKEFGQASFKGLVDEFILETKEGNINLNKICFVAGLGGKDNRDGSFTYYISEPI
                     VANEPKGLGPFILAAAENNLLN"
     gene            complement(11736..12572)
                     /locus_tag="Clocel_2257"
     CDS             complement(11736..12572)
                     /locus_tag="Clocel_2257"
                     /inference="protein motif:PFAM:PF01261"
                     /note="PFAM: Xylose isomerase domain-containing protein TIM
                     barrel; KEGG: cbe:Cbei_0450 xylose isomerase
                     domain-containing protein"
                     /codon_start=1
                     /transl_table=11
                     /product="Xylose isomerase domain-containing protein TIM
                     barrel"
                     /protein_id="ADL51996.1"
                     /db_xref="InterPro:IPR012307"
                     /translation="MRIGVRGHDIGKFSLDELATRIKEKDLKSIQFVMKKAITEFEVTK
                     GCMTPGLARYIKETFDRHNVDISILGCYINMSHPDDEELQELLDLFKDHIRFARDLGCS
                     MVGTETGALNKEYVYGPENHTEEAFQRCLNSLKIMVSEAEKFGVMVAIEGVARHVINTP
                     TKMKRALDEINSNNLQAIFDPYNFLTNENYMNQDELIKEAFELYGDRIILIHAKDFIVE
                     NGQVKQVAIGTGQFNYPLLLSLIKSRKPHIDIILEGTTPQDLDNSIKYIKEIYDRV"
     gene            complement(12668..13294)
                     /locus_tag="Clocel_2258"
     CDS             complement(12668..13294)
                     /locus_tag="Clocel_2258"
                     /inference="protein motif:TFAM:TIGR01182"
                     /note="KEGG: cbe:Cbei_0462
                     2-dehydro-3-deoxyphosphogluconate
                     aldolase/4-hydroxy-2-oxoglutarate aldolase; TIGRFAM:
                     2-dehydro-3-deoxyphosphogluconate
                     aldolase/4-hydroxy-2-oxoglutarate aldolase; PFAM: KDPG and
                     KHG aldolase"
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydro-3-deoxyphosphogluconate
                     aldolase/4-hydroxy-2-oxoglutarate aldolase"
                     /protein_id="ADL51997.1"
                     /db_xref="GO:0003824"
                     /db_xref="InterPro:IPR000887"
                     /translation="MFEKIYSTLKEEKAVAVIRTKTYDEAKEISIAAINGGMKIIEVTM
                     SVPNAPKLIKELKEEYKDACVGAGTVLSKDAVDQCIENNADFIVSPCFDEEVIVYANQR
                     KVLIIPGLMTMSEVNNAYKLGLRFIKVFPGNVVGKAFIGAAKSIFPDLSIMPTGGVNKD
                     NIGEWIQAGADCSGIGSDLNKIYKSNGTEGVTEYCAEVVAKVKSL"
     gene            complement(13367..14314)
                     /locus_tag="Clocel_2259"
     CDS             complement(13367..14314)
                     /locus_tag="Clocel_2259"
                     /inference="protein motif:PFAM:PF00294"
                     /note="PFAM: PfkB domain protein; KEGG: cbe:Cbei_0461
                     ribokinase-like domain-containing protein"
                     /codon_start=1
                     /transl_table=11
                     /product="STP|PfkB"
                     /protein_id="ADL51998.1"
                     /db_xref="InterPro:IPR002173"
                     /db_xref="InterPro:IPR011611"
                     /translation="MDVITIGDAMIAMCPKAKGPIIFCNTFERKLGGAELNVIIGCARL
                     GIQSGWISRLGNDDFGKYIMKTVRGEGIDISEVKLVDNYPTSVYFREVLADGSSRSFYY
                     REKSPTSTMKCEDLNEEYFKNAKVLHITGVFPSIAKNNQEIILEAVKLAKKHGLVISFD
                     PNIRLKMWTKEEAKSYIEKILPNVDILLIGDEEIEILLGEVSIPDAIKTFHYYGIGKVI
                     VKKGAKGAVGSDGKNVYEVDAIKPKALVDTVGAGDGFAAGFLTSMIKGETLENCVKFAN
                     AVGSLVVGVEGDNEGLPCYEDVLVHLGQAKKIER"
     gene            complement(14471..15253)
                     /locus_tag="Clocel_2260"
     CDS             complement(14471..15253)
                     /locus_tag="Clocel_2260"
                     /inference="protein motif:TFAM:TIGR01832"
                     /note="KEGG: cbe:Cbei_0448 2-deoxy-D-gluconate
                     3-dehydrogenase; TIGRFAM: 2-deoxy-D-gluconate
                     3-dehydrogenase; PFAM: short-chain dehydrogenase/reductase
                     SDR"
                     /codon_start=1
                     /transl_table=11
                     /product="2-deoxy-D-gluconate 3-dehydrogenase"
                     /protein_id="ADL51999.1"
                     /db_xref="GO:0008678"
                     /db_xref="GO:0051287"
                     /db_xref="InterPro:IPR002198"
                     /db_xref="InterPro:IPR002347"
                     /db_xref="InterPro:IPR011286"
                     /db_xref="InterPro:IPR020904"
                     /translation="MSSILNEFSMDFFRLDGKVAIVTGGNTGLGQAYAMALAKAGADLV
                     ITTHGTNWEETRKLIENEGKRVVFVQAELTNKEDRKKIVDVSMKEFGRIDILVNNAGII
                     KRAPLLEYKEEDWNSVMDINLNALYFLSQEVVKIMVNQGSGKIINIASMLTFQGGKFVP
                     AYTASKHGVAGITKAFANELAFKNIQINAIAPGYIKTANTGQIREDEKRNKEILDRIPA
                     EKWAEPFDLMGAVVFLASKASDYVNGHILAVDGGWLVR"
     gene            complement(15398..16035)
                     /locus_tag="Clocel_2261"
                     /pseudo=""
     gene            complement(16047..16850)
                     /locus_tag="Clocel_2262"
     CDS             complement(16047..16850)
                     /locus_tag="Clocel_2262"
                     /inference="protein motif:PFAM:PF00106"
                     /note="PFAM: short-chain dehydrogenase/reductase SDR; KEGG:
                     cbe:Cbei_3371 gluconate 5-dehydrogenase"
                     /codon_start=1
                     /transl_table=11
                     /product="short-chain dehydrogenase/reductase SDR"
                     /protein_id="ADL52000.1"
                     /db_xref="GO:0016491"
                     /db_xref="InterPro:IPR002198"
                     /db_xref="InterPro:IPR002347"
                     /db_xref="InterPro:IPR020904"
                     /translation="MNIINNFSLEGKIALVTGAAYGIGFALAKACAEAGATIVFNDINQ
                     DLVNQGIKSYEELGIKAHGYVCDVTDEDAVNELVATIEKEVGIIDILINNAGIIKRIPM
                     LEMKAEDFRKVIDVDLNAPFIVAKAVIPGMIKKGHGKIINICSMMSELGRETVAAYAAA
                     KGGLKMLTKNIASEYGEYNIQCNGIGPGYIATPQTAPLREVQADGSRHPFDQFIVAKTP
                     AARWGTPEDLAGPAVFLASDASDFVNGHILYVDGGILAYIGKQPK"
     gene            complement(17121..17951)
                     /locus_tag="Clocel_2263"
     CDS             complement(17121..17951)
                     /locus_tag="Clocel_2263"
                     /EC_number="5.3.1.17"
                     /inference="protein motif:PRIAM:5.3.1.17"
                     /note="KEGG: cbe:Cbei_2458 5-keto-4-deoxyuronate isomerase;
                     PFAM: KduI/IolB isomerase"
                     /codon_start=1
                     /transl_table=11
                     /product="4-deoxy-L-threo-5-hexosulose-uronate
                     ketol-isomerase"
                     /protein_id="ADL52001.1"
                     /db_xref="InterPro:IPR007045"
                     /db_xref="InterPro:IPR021120"
                     /translation="METRYANHPDDSKKYDTEELRKHYLQEKIFEKDQISLTYSHVDRI
                     IFGGAMPVEEKLSLEAAEELRADYFLERREMGAINVGGSGVIILDGKKYQLDKYEGIYV
                     GMGTKEIQFVSLDKNNPAKFYINSVPAHTSYPTVKIDRNKAVIADLGTQENMNKRTIYK
                     FIHPEVCESCQLSMGVTMLKEGSGWNSMPCHTHERRMEVYFYFDLPEDQRVFHLMGQAQ
                     ETRHIVMANEQAVISPSWSIHAGIGTSNYTFIWGMCGENKTFDDMDNLATKDLK"
     gene            complement(18387..19148)
                     /locus_tag="Clocel_2264"
     CDS             complement(18387..19148)
                     /locus_tag="Clocel_2264"
                     /inference="protein motif:PFAM:PF01614"
                     /note="KEGG: cno:NT01CX_1476 IclR family transcriptional
                     regulator; PFAM: Transcriptional regulator IclR; regulatory
                     protein IclR; SMART: regulatory protein IclR"
                     /codon_start=1
                     /transl_table=11
                     /product="DBD-Pfam|TrmB,DBD-SUPERFAMILY|0040266"
                     /protein_id="ADL52002.1"
                     /db_xref="GO:0003677"
                     /db_xref="InterPro:IPR005471"
                     /db_xref="InterPro:IPR014757"
                     /translation="MQEVVQSVDRALCILEILSDYEDGLGIAEISEKANLHKSTVYRFL
                     NTLIYKGYVTQDTSTSKYLLTLKLFELGNKRIEKMNLVTVAQPYLRELMKKTDEVIHLA
                     VREDNELIYVAKVEPKKSIIMYTRIGMRKPMYCTAMGKAIMAELTEEEVKNIWDTSDRK
                     VYTDNTIVNLSELKNNLREVRSKGYAIDDQEVENGIICMGAVIKDYRSKICGAISVSGT
                     IMSVDEEKKEIIAEELLQCANKISKDLGYNI"
ORIGIN
        1 ctatttttga tttttaaaat atattactgc attgttatag caaatatctc ttaccacttg
       61 tcctaatact tccatatcag ctggatattc tccgttttca actaactcgc ctaagtagtt
      121 gcaaagtatt cttctaaaat actcatgtcg tgtgtatgat aaaaagctac gtgaatcagt
      181 aagcattcca acaaatttgc taacaagccc taattgagat aatgctgtta attgttttat
      241 cattccatct ttttggtcaa ggaaccacca accagatcca aattggattt tactagcaat
      301 tccaccacct tggaagtttc caagcatagt tgcaagaact tcattatctt taggatttaa
      361 acaatataat attgtctttg gtaacttgtc ttgagattct agtgcatcta ataattttga
      421 taaaggttga gctatttcac catcatcaat actatcaaag cctatatctg ggcctagttt
      481 tttaaacatt ctactattat tgtttcttaa agcaccaata tgtaattgta gaatcattcc
      541 aagttcatga tacatctcac ttaacttaat cattgttaat gtaacatatt tttctattgc
      601 ttcttgtgat aaagcttgac cagctaatgc tttcttaaaa atagaatcaa cttcttcttc
      661 agtagtttct ctaaaataaa ctctatccat agcatgatct gttattgtgc aaccattctc
      721 aacaaagaat ttcagtcttt ttttaaggac atctaaaagc tttgcataag atgtaatagt
      781 tgtattttca gtagcaccta ataattttat atattcagca aagtcttggt ttcctatctt
      841 aacggctttg tcaggtctcc atgaaggtct tacttcacat gtaaaattct tatcactagc
      901 tatttcttga tgaaattcta aactatcagc tggatcatct gtagttccaa tatacttaac
      961 attggaattc ataattattg actttgcact gaatccagaa ctctttatta cttcattgca
     1021 tttattccaa atttcttcag catttttttc acttaatact tctgtcacac caaaatatct
     1081 tctaagttct aaatgcgacc aatgatatat tggattgcct attaaatatg gcattacaga
     1141 agcaaatgcc ttaaactttt gaaagtcgct tgcatctcct gttatatact tttcatcaac
     1201 gccgtagctt ctcattgctc tccatttgta gtgatctcca tataaccata tctcagtgat
     1261 attgttatat tttttatctg tagcaatttg ctccggaatt agatgacaat gataatcaaa
     1321 aataggcata tccttagcat attcgttata aagtgttttt gcagtttcag ttgataataa
     1381 aaaatcttct cccataaact ctttcatgtc aaataccctc ctataatgta actccatctt
     1441 ttaatatagc tatttctcta taatcattaa cttcgttctt tgctctataa tcacctgatg
     1501 cagtatctat aattaatttt aagaattctt catcaatttt ttcaggatta ttggagccaa
     1561 taagttctcc agcgttaaaa tcaatccaat ttttctttct gttatataaa tcagtattag
     1621 ttgaaatttt taaagttgga acactaccac cgtatggagt tcctcttcca gtagtgaata
     1681 atacaatatg agctccagca gctgctaata ctgtaactgc aatttgatca ttaccaggtc
     1741 ctgagataag atttaacccc gttttggtag ctctatcacc atattgcaaa acatctgtta
     1801 caacagcttt accacttttt tgaacacaac ctagtgattt ttcttctaaa gttgtaattc
     1861 cacctttttt atttcctggt gaagggtttt cataaatcac ttgattatat ctcataaaat
     1921 attctttgaa atcatttata agctctacac tcttatcaaa tatctcttta tttatagacc
     1981 tatcaaacag aatagtctca gctccaaaca tttctggtac ttcagtttgt atagctgttc
     2041 cacctaaaga agttatttca tttgatattc ttcctagtaa tggattagct gtaacccctg
     2101 aaaatgcatc tgaacctcca cattttaatc ctatctttag tttagatata ttaacatgtt
     2161 cacgttcaaa cttagacgca tattgaatta attctcctaa taacttcttt ccttcttcaa
     2221 tttcatcttc aacatcttga acccttaaaa atttaactct ttcttcattt ataggttcaa
     2281 gaagttcctt aaaactttct aaagtattgt tttcacatcc aagagcaact acaagtacac
     2341 ctgctgcatt aggatgattt actagattcg ctagaatttt tctagtgttc tctaaatcag
     2401 agtctaattg agaacatcca aatggatgtt caaaatgata aacaccatct actttatcat
     2461 ttataagttt atttccttcc cttgctaagt ttgcacaagt tttattaata cagccaactg
     2521 tattaataat ccatatttcg tttcttatac caacttcacc attgtcacga acatatcctt
     2581 taaaggtaat agcgctattt tctttaacag tttgtttcat agcacccttg aagttgtatt
     2641 ctaatatttc tccaagacct gttccaaggt tatgagaatg aatccattct ccaaccttga
     2701 tatcttcttt agcctttccg atactgtagc catatttaag gacatcttgt cctttttcta
     2761 tattttttat ggctacttta tgacctttag gtatatcatt tagcaatttt atttcttgtt
     2821 catcagcaac aatgacttcg cctattgtac tatcttctaa tagtacgact acatcatcat
     2881 catgatttat cttaactatt ctatgcatac tttctctcca aactttccaa tgcttcactt
     2941 acagctacag ttaacccttc aattttagtt aaatcttcac cccatagttc tgtattactt
     3001 aatatggctt ttacataatt ctgatttttt attgagtatt ctttgttcat attgcacata
     3061 aagtctaata cgtttataac gtcaaataca ggatattctt ttcctttaaa attgtgtcct
     3121 atatatttgt cttccttttt ttctatttgg taaaatctaa gaagaccagc aagacctatt
     3181 accatgttct ttggtaaaga attgttatct tcgatatatg cttttacagt aggtaaatct
     3241 ctattaacaa acttagatac tgagttcatt gatatagatt ctaatttatg ttttaagtga
     3301 ggatttctaa atctttgaag aattgtctta gcatatcctt ctgcatcctc attcttcaat
     3361 gatggtatta tttcattttg taatgcttca tttaaaaatg ctttttcttc tggatcctca
     3421 actaactcat ccactctttc aaatcctttt aaaattccta gtggagttat caaagtatgt
     3481 gacccattta gtatactaac ttttagtaaa tgtatgtcat ataatgaatc tgcccatttg
     3541 acatttaatc cagctgattt taatggtaat attttgtcat attcttcact accttcgatt
     3601 ccccataaga aaaatggctc acatactgaa gcagcttcat ctatataacc taacttttca
     3661 aaatatgctt ctgtattttc tcttgggaat cctggaacta ttctatcaac taaattattt
     3721 agaaatacac atgattcatt tacccaagtt ttaaactcat cactagtccc aaaactttca
     3781 gcgtgctttt ttaccatttc ttcaaggact ttaccattat catctagcaa ctcacatggg
     3841 aagataagta atttttttgt cttatcttta atattttcaa atctatgcat taagaatgca
     3901 gtcaatttac caggatataa tccgtcaact gatactttat ctaattctac ttctttataa
     3961 gcaagtccag cttcagtagt gttagatata attacttcta agctttcaag ctctgctatc
     4021 tccataaatg aattccaatc aacattatag ttgaatactt ttgaaaatac tgagattata
     4081 tcactttcat caacttcaac attatcctta aaacctcttt gcgttactgt atataacata
     4141 tcttgttctt ttaagatatt tatcttttta tcaaaatcta aaggacaagt taatgctact
     4201 gatccttcat attttccagc ttctattgct ttatataaca tccaatcaaa aaatgatgtt
     4261 aaaaagtttc cttcacctat ttgcataact tttattggac tttttacaac cttatcatat
     4321 atcgatcttt gcttttcatt taaacattca acacttagtt tctttagcat aagaatattc
     4381 acctcataat atttttttaa tctatagttt tactttttat taaatttact tgagatttac
     4441 ttttgctcca cctgggattt caactatatt atcatcattt ataacaaccc aagctgatgc
     4501 tactgaagga ttatagacaa aacttccatc tgctgcaaac ttcaaattat cacacacctt
     4561 tagataatca actatttcta tattggttgc ataccaaata tcatctctat gacctattct
     4621 tctgcaaaat tcttctataa cttcccagtt gttatctttt tcaaattcat aactatgacc
     4681 ccaaacataa aacatatata aatattgctt tttggataaa ccaataaatt cgtctgcatg
     4741 ttcaagtaaa ttatgcagat gatgacaagt agattgccac tgataataat ctgttggcat
     4801 cttaaaattg tcactatttc caactattct tgaatactct attccaacat gtcttagcat
     4861 atcttttatt tcattattgt aagaaccatt tggataagag aatcctctta cagtatagtc
     4921 aacaattgat tctaaaactt ttctatcttc taaaatttgt tctattacct gaggcatagg
     4981 acaccgagat atagtcggat gagtcacggt gtgacaagct acttcatgac ctttatataa
     5041 ttcctttact tcttctttag gaattctttt ttcatatggc aaggtcaaca ctggatcatt
     5101 ttgttccata tatcctgaat ttaaatggaa tgtaccttta attccataat cattaaaaag
     5161 attaactaat cttctatctg taattttccc atcatcataa ctcatagtta atactttaaa
     5221 ttttccatcg ggaaaacatc tgtatatctt ggccactttc cttcatctcc taaaaattaa
     5281 gttcttataa actttgaact acccatataa acatatttat tacttaaaat tcaaacatgc
     5341 tttaaagtat tattaataat aaatttaatc tattatttta agcatctata aactgtcata
     5401 catcttaatg taattactta aatccttgct tgtataccaa gtgtttaaaa ctgatactta
     5461 aactggtatt atttttcaca taaaaatcaa tgataaatcc cttataattg catgatttcc
     5521 tataaacagt ttgaaaattt ctatgttcta attcctgtgc ccttccctta cttgtatact
     5581 agttatagtt ctattataca tcttttgtta cattttgcaa cccttttcaa ggcttttctc
     5641 agagatttat cactaaaata tcaatataaa tattaaaaac aaacctattt taactgttga
     5701 ttaaagtaat agaccttata ttcttaaaat ttattttaag aatataaggt ctattactga
     5761 gatcacatta aactcctatg aacatattga aaaacaatat aacatatgaa tttttttatc
     5821 aaatcctata taagttatat ttttgtgaaa aaaagatgct tcatataagc atctttttaa
     5881 aatcagtatt ctatttattt atcttgaaaa agttatgaga ttcatttttt tcctctagaa
     5941 gatgttccca actcttcttt gtatatctca tatgatcatt aattaatgat tcgactttgt
     6001 ctatatgctt ttcttttata acctttataa actcagcatg ctgttctact acatccttct
     6061 taggatcctc agcctgagat agtagtctca ttctattata atgagtactt atattaagta
     6121 tactctgcca aacatttacc ttattaactc ctaagaaaaa cagttcatgg aagcggttat
     6181 ctaacttatg gaattctttc tcccccccct ccatatctgc aagtatttgt tgggcatata
     6241 gatttttatc caattcaaca aatagctctt cattgaactc ctcacaagct gattttagca
     6301 ctttttcttc taatgcaaat ctcataaacc tagcttcttg aactaaatca agatctatta
     6361 atgaaacata cgtcccagat tgtggtttta cctctattaa atgttcactt ttaagtttca
     6421 tcaaaacttc tcttatagga gttcttgata tacctagttt ttctgatagt tcaatttcac
     6481 ttagtaattc tcctggctta agttctagag acattatgtt ttctttcaac actctataag
     6541 cataatcttt tccactttca ttctcgtttt tatcatatag taccaaatat tatctcctcc
     6601 atacgtaccc atatatcatt ttcttatgtt tagtatacta gatactctaa attattcaat
     6661 atattaactt aaaaataact attaaattat ttcttgaaac tcattattta catggaaagt
     6721 tttatctgct aacttcttac catttataga tacgttttta aatgttatat ttttaacgtt
     6781 ttgaagaata gcttctccgt taacaccatt taaaatagca tcttctataa caatattttc
     6841 tataggcgca tgctcaaacc cttttatgta caaagcattt tttgcatcaa tacttccacc
     6901 ttcgacagtc tttatgtttt ctaatgtaat atttcttaat ataggtttgt gatctccatt
     6961 agtaccttct tcatagaaaa aatcggcatg tataacagct attttagact tattaacagt
     7021 gctgtttttt acgtagatat tttctaactt tccaccacgt tctgcattag tcttaaatct
     7081 tataggataa tcaagttctt tactatcgaa atagttatcg tgagcaaata tatcattaac
     7141 tcctccagat atttcactac caatagtaat accaccatgc ccgtccttaa actcattata
     7201 tcttataata acattttcag taggaacacc aatatttctt ccttcattat ttcttcctga
     7261 ctttatagct atacaatcat cccctgttaa aaagtaacaa ttctctataa tcatatcttt
     7321 acatgattct ggatctacac catcattatt atataaattt gtgcccactt ttatattatc
     7381 tacttttata ttttcacaga gtacaggatt tatctcccaa aaaggagagt taattatttt
     7441 tacatctttt ataagaatgt ttttagattt atatggttga ataaatggtg gtcttatagt
     7501 ggaaacatca tccccaaata ttctttctgt tcttacatca gcattttttt gacctaactc
     7561 aaataatctt tctctttgaa tttgctgatc ttcttcttta aaatatccaa acttccatgg
     7621 catccaatta aattcatcag catttccatc tagtacccct tccccaacta tagctatatt
     7681 ttcagcttca taagaatata taaatggaga aaaattcatc atttcaaccc cttcccatct
     7741 agtatatact aatggataga attcatttgt cttatttcta acaaatctaa gtattgcatt
     7801 tttctgaatt tcaagtataa cattactttt taatgttata gctcctgtat aatagacatt
     7861 aggagcttca ggattttcac ttcctggtat tataactttc ccaccgtctt tattactatt
     7921 agcttcatca atagctcttt gtattgcatc accataataa gttacttctt gaacatttct
     7981 tattaaagct tttgctatat actctttatc ttttttaagt tctgactttg tccctttata
     8041 agttccatca acatgagtaa agtattcttc attgatttct ttaataagct ttgtatatct
     8101 ttcatctgta attctatatt ccattaagtt acctatcata ggcatgtttt tatttacttt
     8161 ttcttcgata aaatcataaa gcttttgatt ccactgaaat ttattttgtt ccataaatgc
     8221 tcctccaaaa aaaaatttta caagttcatt tttcattata taataactac actgttatct
     8281 ataaccaaca atcaatagag acgcttcata aggtatacta ctttttcaac atatccgtat
     8341 actttcggtt gtagccacaa taatgaaccg tatatattat aaaaaaatat agtagataaa
     8401 cataagatac atttacctac tatatattat caattattta tttgcactaa atatttatat
     8461 tttatgcgtt agcagctttt gaatggtatc ctacattgtt gtttccaaaa caattttcat
     8521 aagcaaatcc tgttaattct tcgattgctt ctctagcttc tggtgtaaca tctgctttag
     8581 aaccaccagc ttttactcta ttaacttcat caactaaaat tttatgagtt tctttattta
     8641 attttaattt tcttgaaaca attacagtag taataagtaa cacagttgga actacagttg
     8701 cgaaaataac tacccctact atagctaatt gaggttgttc tttagcacct ttaacaaatc
     8761 caaatgcttg taatccaaag cccagtaata atgattctac accgtatgcg attttagaca
     8821 tagctccatt aacccctgag aatatacctt ctcttctagt acctgttaca gcttcatcaa
     8881 tatcagccat gaatggtaat tggaatactg gtatatagtc agcaccaccc ttaccaactg
     8941 tatttatgat ttgaactgca actaaagctg gaattattaa gcttgtacct tttaagaatg
     9001 ttaatccaaa taatccaagc gcagctaaaa caactagtga agtagcaact cttaaagttt
     9061 ttggtccgcc aaatttataa gcaagagcaa cgaacaatgt taacgttgct aaagaaatta
     9121 atgttgagaa agctgaaata taacctgtaa cagacttact taacactaaa caataaacta
     9181 cgaaataagt aaatacgcta ttagctaagt ttttataaat tccgattaaa agcatcataa
     9241 ttgtatgtat tctgaaagat tttactttta atgttgaaga gatatctaat agtaattttt
     9301 tcaaaacttg tcctatacca tgagcttcgt ttgagtaaac gatgtcttct ggtgctcttt
     9361 caaatgtaag tgaataaact acaactaaag aaagtgcaag tataactgca taaacaatac
     9421 ctgttaaatg gaatgcatct ggattatttt caccatacat tacgaataat tgagctggta
     9481 tgaatgaaga tatcatatta gctattgttc cacaataaga tttagcagca acaagttttg
     9541 ttttatcagc tgcagtttgt gccatttctg ctggcaatgc aattgtagaa acgataacca
     9601 tagtaaatac catttcccaa atcatgttga ttccgaaata gtatgcataa gagtgaccaa
     9661 ctgtccacat cattggaaac acaagtaaag ataatggtgc tccaagtaat ataaagaatc
     9721 ttcttcttcc aaaacgtcta cctaatctag tttttccaaa gttatcagta atgaacccca
     9781 ttataggatt tagagcagca tcaaggaatc ttgtacctgc gaatatagac cctgcttgta
     9841 atacactaag attacaaaga gatgtgtaaa atattaatag gtataattga actatattct
     9901 gtgatccact tcctaagaag ttgatagatg cataacctat catatgttta atgctaattt
     9961 tctttttcat ttttttccct ccatttttta ttttcgtgct ttttaataat aattaagatg
    10021 attgcaataa gtttacaata atcattatta actttagttt aataaattgt tttctgcagc
    10081 tgctaatatg aatggtccta agccctttgg ttcatttgca actattggtt cgctaatgta
    10141 ataagtaaat gatccatctc tgttatcttt accaccaagt ccagctacaa aacaaatctt
    10201 atttagattt atgttacctt ctttagtctc aagaataaat tcatctacta aacctttaaa
    10261 ggatgcttgt ccaaattctt ttaaatcttc tcttaacaag cctattctta caccttttaa
    10321 tatagaataa gctatcattg aagaaccaga agcttctaag taattacctt ttctatcgcc
    10381 ttggtctaat acttgatacc aaacatggct atctttgtca gctactttta ttaaagcatc
    10441 aacagtattt tggaatatct ctaacatttc agctctatgt ttattatctt taggtaatac
    10501 ttctaaagta tcaactaacg ccataacata ccaccccata gatctactcc agaaatgtgc
    10561 tgataagcct gtttctttgt ttgcccaagg ttgtactcta gcatcatcat aagcgtgata
    10621 taataagcct gttttttcat ctataagatg ttgttttgct ataacaaatt gttttgctat
    10681 atcatcaaat tcagcaacat ccccgaattc gtttacatac tttgcataaa aagttgcacc
    10741 catatataat ccatctaacc agatttgttc tggatatatt tctttatgcc agaagacacc
    10801 ttctcttgtt cttggatgat tattaatttg tgttcttaat aattctaagg cttttttata
    10861 tttttcttcc ttagttgctt gatataaagt caatacaatt ttaccattat ttaaatgatc
    10921 gatattatat tcatctactc tatatcctct aatacttcca tcttctccta taaaagtatc
    10981 catagcatct tttacatatt tgaaatactt ttcgtcttga gtttgtttcc atacctcagc
    11041 gataccatct aaagttaatc caaactcata agcccagtag ctagttaaat cagtatttct
    11101 tgctatgact gaatcagcca tccattttgc ataatctctc attgcgacat tccctctcct
    11161 atttctatat tattctttca attttccatt tcttgaaaac gtattctttc cacatcttta
    11221 ttatattacc tagctattat aaagtcaata gtaattagta tattagtttt actttttttt
    11281 atattttttt acgttttttt attattggaa aagatcgcct ttataatctt aatatctttg
    11341 tatttttact ccttatcaaa taaaccattg atacaagccg atttattaaa ataaatgttg
    11401 ataattcagc tttatttctt taatgttttt tcgaaattca ccccctaaaa gattatatca
    11461 ctcctcccaa ctagtataca acacttttat atttttatta cattttttct ttttttaaaa
    11521 tatataatta catatttgtt atagaaattt catcaaacag aatacaagta tacaactttt
    11581 tattcttttt aaaaataaga tttttattta tgcattgata acaaatgaat ctttgaagtt
    11641 tttatacaaa atctactttt taaaattgta tacaaaatgc acaaaaaatt gcaactattt
    11701 tagcccaagt aattaggtta aaatagttgt atttcttata ctctatcata gatttcttta
    11761 atatatttta tgctattgtc taaatcttgt ggagttgtcc cttcaagaat aatatcaata
    11821 tgtggttttc tcgattttat taatgacaat aataaaggat aattaaattg tcctgttcct
    11881 attgctactt gcttaacttg tccattttct actatgaaat cttttgcatg aattaatatt
    11941 attctatcac catataactc aaaagcttct ttgataagtt catcttgatt catataattt
    12001 tcatttgtca aaaagttata tggatcaaat attgcttgaa gattatttga attgatttca
    12061 tctaacgctc tcttcatttt tgttggtgtg ttaattacgt gtcttgcaac cccttcaata
    12121 gcaaccatga ctccaaactt ctctgcttca ctaaccatta tttttaaaga atttaaacat
    12181 ctttgaaatg cttcttctgt atgattttct ggtccatata catattcctt attaagagct
    12241 cctgtttcag taccaaccat actgcagcca agatctctgg caaacctaat atgatcttta
    12301 aataaatcta ataattcttg taactcctca tcatctggat gtgacatatt aatatagcaa
    12361 ccaagaatac ttatatctac attatgtcta tcgaaagttt cttttatata acgagctaat
    12421 cccggagtca tacatccctt ggttacttca aactcagtta tagctttttt cataacaaac
    12481 tgtatacttt ttaaatcctt ttctttaata cgtgttgcca attcatctaa tgaaaactta
    12541 cctatatcat gacctcttac tcctattcgc atcagtgcct ctccttactt taaatactat
    12601 atttctcttt ttctcaaata ctattaatag tataaaagaa tgttatttaa acattctttt
    12661 atgacaatta taaacttttt actttagcaa caacttcggc gcaatattca gtcacacctt
    12721 cagtaccatt acttttgtat attttattta aatcgcttcc tataccacta caatcagctc
    12781 ctgcttgtat ccattcacct atattgtctt tattaacacc accagttggc attatactaa
    12841 gatctgggaa aatagattta gcagctccta taaatgcttt tccaacaaca tttccaggga
    12901 acacttttat aaatctaagt cctaatttgt aagcattgtt tacttcagac attgtcatca
    12961 aaccaggaat tattaatact tttctttggt ttgcgtaaac tattacttct tcatcaaaac
    13021 atggtgaaac gatgaaatca gcattatttt caatacattg atctacagca tctttagata
    13081 atacagttcc agcgccaacg caagcatctt tatactcttc ttttaattct tttattaatt
    13141 taggagcatt aggaacactc atagttactt ctataatttt cattccacca tttatagctg
    13201 caatacttat ttcctttgct tcgtcataag ttttagttct tataacagct acagcttttt
    13261 cttcttttaa agtactataa attttttcaa acatttattt acacctcatt tttgtttctt
    13321 tatatcaaaa ctaactatga tacatctata aatttcaata ttttctctaa cgttctattt
    13381 tcttagcttg tcctaaatgt actagaacat cttcatagca gggtaatcct tcattatcac
    13441 cttcaacacc aacaactaaa gatcctactg catttgcaaa cttaacacaa ttttctaaag
    13501 tttcaccctt aatcattgat gttaaaaatc ctgctgcaaa accatctcca gctccaactg
    13561 tgtcaactaa agcttttggt ttaatagcat caacttcgta aacattttta ccatctgatc
    13621 ctactgcacc tttagctcct tttttaacaa taacctttcc tatgccataa taatgaaaag
    13681 tttttattgc atctggtata gatacttctc ctaaaagaat ttctatctct tcatcgccaa
    13741 tcaataagat atctacatta ggtaatatct tttcaatata agacttcgct tcttctttag
    13801 tccacatttt tagtcttata ttagggtcaa aggatataac taaaccatgt ttttttgcta
    13861 gtttaactgc ttctaatatt atttcttgat tattcttagc tattgaagga aatacacctg
    13921 taatatgtag tacttttgca ttcttgaaat attcttcatt tagatcttca catttcattg
    13981 tacttgtagg tgatttttct ctataataaa aggatctgct agagccatct gctaagactt
    14041 ctctaaaata tactgatgtt ggataattat ctacaagttt aacttctgaa atatcaatac
    14101 cttctcctct tacagttttc attatatatt taccaaaatc atcatttcca agtcggctta
    14161 tccaacctga ttgaatacct aatcttgcac aacctattat aacatttagt tctgctccac
    14221 ctagttttct ttcaaaagtg ttacaaaata ttattggacc ttttgcttta ggacacattg
    14281 ctatcattgc atcacctata gtaataacat ccatatattc ttgcctcgct ttcaatctat
    14341 tattttttat tattaacatt ttacttctaa aacttttatt gttcaaatat atatcaaaat
    14401 gtaatcaagt gtttcgagaa atttttataa tttacttaat acagcaagta ttaaccaaag
    14461 ataactttca ctatcttact aaccagccac catcaactgc aaggatatga ccattaacat
    14521 agtcagatgc tttacttgct aaaaatacaa ctgcacccat taaatcaaat ggctcagccc
    14581 acttttctgc tggaattcta tctaaaattt ctttatttct tttttcatct tctcttattt
    14641 gtccagtatt agctgttttt atatatcctg gtgctatagc attaatttga atatttttga
    14701 atgctaattc attggcaaaa gctttagtta taccagctac tccatgttta ctagcagtat
    14761 atgctggtac aaattttcca ccttggaatg ttaacattga tgcaatatta attatttttc
    14821 ctgaaccttg atttaccatt attttaacta cttcttggct taaaaaatat aatgcattta
    14881 aatttatatc cattaccgaa ttccaatctt cttccttata ttcaagaagt ggagctcttt
    14941 ttataattcc agcattattt actaatatgt ctatcctacc aaactctttc atagaaacgt
    15001 ctactatctt tttcctatct tctttattag ttaattctgc ttgaacaaat acaactcttt
    15061 taccttcgtt ttctattaac ttccttgttt cttcccaatt agtaccatgg gttgtgatta
    15121 ctaagtctgc tcctgcttta gctaaagcca tagcataagc ttggccaagt cctgtatttc
    15181 caccagtaac tatagctacc tttccatcca atctaaaaaa atccattgaa aactcattta
    15241 aaatactcga cattataatt cactcccatc ataatttaat tgtttatgtt agcgaaaacg
    15301 aaacatgata taaaagcctt catatataaa gaaaagagcg gattattcat gtccgctctt
    15361 aacttttcta ctatattaga tgtgtcttat cagcttatta ttctaatatg cttcttatat
    15421 aagactctat ctccttgcac tgacaattat taaagaagta ttccttaaac ttttgcccgc
    15481 taacagcacc ttttaataag gcttgatcta tttcttttaa aatagtaatc atatccttat
    15541 gggttactat ttttacttca tctaaaatct ttttatttct ttgttctggt ataactctat
    15601 cttttggata tccttgtcca ctttcgcctt ggaatagttt ttcaaagata tattctaaat
    15661 ttaattctgc tccccatcca aatccttttg caaaaggtaa tgatatagaa ttcccatcat
    15721 taatttgtgc aaacatatat gcatcggatg gatctactat gtgaccacat aatactcctg
    15781 gaaatgaatt agcagcaagc attgcgcctt ctcctgttcc acatccagtt attacataat
    15841 ctgcagccct gaatttaata atatagctgt taatatgcca ttttgaacat atgttaattg
    15901 agcctcatct tcagcactat acattccgta gttaaatact tcatgtcctt ttggttctac
    15961 tactttcttt aaggtttcgt agattaaacc attttttgat gcttggctat tttcatttat
    16021 taaagctatt ttcattgtcc taccccctat tttggttgtt ttccaatgta agctaaaata
    16081 ccaccgtcta catataaaat gtgaccgtta acgaagtcag atgcatcaga tgctaagaat
    16141 acagctggac ctgctaaatc ttctggagtt ccccaacgtg ctgctggagt ttttgcaact
    16201 ataaattgat caaatggatg tcttgaacca tctgcttgaa cttctctaag tggtgcagtt
    16261 tgtggtgtag ctatatatcc aggtccaatt ccgttacatt gaatattgta ttcaccatat
    16321 tcagatgcaa tattctttgt taacatctta agtccaccct tagctgctgc ataagctgct
    16381 acagtttctc ttcctaattc actcatcata gagcatatgt tgattatttt tccgtgacct
    16441 tttttaatca tccctggaat tactgcttta gctactataa atggagcatt taaatctaca
    16501 tctataactt ttctaaaatc ttctgctttc atttctaaca ttggaatacg tttgattatt
    16561 ccagcgttat tgattaatat atcaattatt cctacttctt tttctattgt tgcaactagt
    16621 tcatttacag catcttcatc tgtaacatca catacataac catgtgcttt tattcctagt
    16681 tcttcataac tttttattcc ctggttaact aaatcttggt ttatatcatt aaatactatt
    16741 gtagctccag cttcagcaca agcttttgca agagcaaatc caataccata agcagcgcct
    16801 gttactaatg caattttgcc ttctaatgaa aaattgttaa ttatgttcat tgaactttcc
    16861 ctccataatt taagtgtgtt aaacgtgttt gattctgaat ttgtttgtgt tattgtgtta
    16921 cgtgttattg agatattttt ttgagatatt cttttttaga gatatatatt ctttttttag
    16981 agatatattt tttagggaaa tagagattat tcccttatgg tttacaatat taaaattatt
    17041 ttttaacttt ttgtatttct atttaatcaa tgagttacac catactatag gtgccttttt
    17101 agagaaaagg tttttaaaat ctattttaaa tcttttgttg ctagattatc catatcatca
    17161 aaagttttat tttctccaca cattccccat ataaaagtat aattgctagt tcctatacca
    17221 gcatgaattg accaacttgg ggatattacg gcttgttcat tagccattac tatatgtcta
    17281 gtttcttgag cttggcccat taaatggaat actctttgat cttctggtaa atcaaagtaa
    17341 aaatacactt ccattcttct ttcatgtgta tgacaaggca tactattcca accgctacct
    17401 tcttttaaca tagtaacgcc catagatagt tgacagcttt cacaaacttc tggatgaata
    17461 aatttataaa ttgttcgctt attcatattt tcttgggtac ctaagtctgc aatcacagct
    17521 ttatttctat ctattttcac tgttggatac gatgtatgag caggtacaga atttatgtaa
    17581 aattttgcag gattgttttt atctaatgaa acaaattgaa tttcttttgt tcccattcct
    17641 acatagatac cttcatattt atctagttga tatttttttc catcaagaat aatcactcca
    17701 gagccaccta cattaatagc acccatttct cttctttcta agaaataatc tgctcttaat
    17761 tcctctgctg cctctaaaga aagtttttct tctacaggca tagctccacc aaatattatt
    17821 ctatctacat gactataagt cagacttatc tgatcttttt caaaaatctt ctcttgtaga
    17881 taatgttttc tcaactcttc agtatcatac ttttttgagt catctggatg attcgcatat
    17941 ctagtttcca tttcacacct cctaaatgtt tttcatatta aaaatattaa ttttattatt
    18001 acctttatca gtaatacgct tccatagcta ctctttattt taaatttaca ccttataaag
    18061 aatatataac tataacaagc acagcaacat aagttgctat attacccccc agtaatcgct
    18121 cgcattatgg attagcgttt cacatcgtga acttaatact attatacgat acgcagtttc
    18181 atttttcaag tagataataa aaaatttgta gaattttttt attgtttttt gtttaactat
    18241 tcttgcattt gaaataaaaa aacaaaccgc tgccaatatt tacatgacaa tgatttgttt
    18301 tttaatctca attattgatt tatatatatg tatctttaat ccctataatt tatattcgtt
    18361 gctcctactg tgtgaacatc tagtagttaa atattatatc caagatcctt tgatatttta
    18421 tttgcacatt gtaaaagttc ttctgcaata atttcttttt tctcttcatc tacgctcata
    18481 atagttcctg aaacactaat agccccacat attttacttc tgtaatcttt gattacagct
    18541 cccatgcata ttattccatt ttcaacttct tggtcatcta tcgcatagcc tttggaacgt
    18601 acttctctta aattgttttt cagttcactt aagttaacta tagtattatc agtgtagact
    18661 tttctatcac ttgtgtccca tatatttttc acttcttctt cagtcaattc tgccattatt
    18721 gctttaccca tagctgtaca atacattggc tttctcatcc caatacgagt atacataatt
    18781 atagactttt taggttcaac tttagcaaca taaataagtt cattatcttc tctaacagct
    18841 aaatgaatta cttcatcagt ttttttcata agttctctta gataaggctg agcaacagtc
    18901 actaaattca ttttctcgat tcttttatta cctaattcaa ataattttaa tgttagaaga
    18961 tacttgcttg tacttgtatc ttgagttaca tatcccttat atattagcgt atttaaaaat
    19021 ctatatactg tacttttatg taaatttgct ttttcactaa tctcagctat tcccaatcca
    19081 tcctcataat cagataatat ctctaaaata caaagggctc tatctactga ttgtactact
    19141 tcttgcat
//
