LOCUS       CP000410                6544 bp    DNA     linear   BCT 02-MAY-2018
DEFINITION  Streptococcus pneumoniae D39, complete genome.
ACCESSION   CP000410
VERSION     CP000410.2
DBLINK      BioProject: PRJNA16374
            BioSample: SAMN02604051
KEYWORDS    .
SOURCE      Streptococcus pneumoniae D39
  ORGANISM  Streptococcus pneumoniae D39
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6544)
  AUTHORS   Lanie,J.A., Ng,W.L., Kazmierczak,K.M., Andrzejewski,T.M.,
            Davidsen,T.M., Wayne,K.J., Tettelin,H., Glass,J.I. and Winkler,M.E.
  TITLE     Genome Sequence of Avery's Virulent Serotype 2 Strain D39 of
            Streptococcus pneumoniae and Comparison with That of Unencapsulated
            Laboratory Strain R6
  JOURNAL   J. Bacteriol. 189 (1), 38-51 (2007)
   PUBMED   17041037
REFERENCE   2  (bases 1 to 6544)
  AUTHORS   Lanie,J.A., Ng,W.-L., Kazmierczak,K.M., Andrzejewski,T.M.,
            Davidsen,T.M., Wayne,K.J., Tettelin,H., Glass,J.I. and Winkler,M.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (17-JUL-2006) The Institute for Genomic Research, 9712
            Medical Center Dr, Rockville, MD 20850, USA
REFERENCE   3  (bases 1 to 6544)
  AUTHORS   Lanie,J.A., Ng,W.-L., Kazmierczak,K.M., Andrzejewski,T.M.,
            Davidsen,T.M., Wayne,K.J., Tettelin,H., Glass,J.I., Rusch,D.,
            Podicherti,R., Tsui,H.-C.T. and Winkler,M.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (02-MAY-2018) The Institute for Genomic Research, 9712
            Medical Center Dr, Rockville, MD 20850, USA
  REMARK    Sequence update by submitter
COMMENT     On May 2, 2018 this sequence version replaced CP000410.1.
            Source bacterial stock (NCTC 7466) is available from the National
            Collection of Type Cultures, London, UK.
FEATURES             Location/Qualifiers
     source          1..6544
                     /organism="Streptococcus pneumoniae D39"
                     /mol_type="genomic DNA"
                     /strain="D39"
                     /culture_collection="NCTC:7466"
                     /db_xref="taxon:373153"
     gene            1..1437
                     /gene="bglA-1"
                     /locus_tag="SPD_0277"
     CDS             1..1437
                     /gene="bglA-1"
                     /locus_tag="SPD_0277"
                     /EC_number="3.2.1.21"
                     /note="equivalent gene in S.pneumoniae TIGR4 = SP0303;
                     equivalent gene in S.pneumoniae R6 = spr0276; identified by
                     match to protein family HMM PF00232"
                     /codon_start=1
                     /transl_table=11
                     /product="GH1"
                     /protein_id="ABJ53661.1"
                     /translation="MTTFKDGFLWGGAVAAHQLEGGWQEGGKGISVADVMTAGRHGVAR
                     EITLGVLEGKYYPNHEAIDFYHRYKEDIALFAEMGFKCFRTSIAWTRIFPKGDELEPNE
                     EGLQFYDNLFDECLKNGIEPVITLSHFEMPYHLVTEYGGWKNRKLIDFFARFAEVVFKR
                     YKDKVKYWMTFNEINNQANYQEDFAPFTNSGIVYEEGDNREAIMYQAAHYELVASARAV
                     KIGHEINPDFQIGCMIAMCPIYPVTCNPKDILMAMKAMQKRYYFADVHVLGKYPEHIFK
                     YWERKGISVDFTDQDKEDLLGGTVDYIGFSYYMSFAIDSHRENNPYFDYLETEDLVKNN
                     YVKASEWEWQIDPEGLRYALNWFTDHYHLPLFIVENGFGAIDQVAADGMVHDDYRIEYL
                     GAHIREMKKAVVEDGVDLMGYTPWGCIDLVSAGTGEMRKRYGFIYVDKDDNGKGSYNRS
                     PKKSFGWYKEVISSNGESVE"
     gene            1489..1728
                     /locus_tag="SPD_0278"
     CDS             1489..1728
                     /locus_tag="SPD_0278"
                     /note="equivalent gene in S.pneumoniae TIGR4 = SP0304;
                     equivalent gene in S.pneumoniae R6 = spr0277; identified by
                     match to protein family HMM PF03083"
                     /codon_start=1
                     /transl_table=11
                     /product="gnl|TC-DB|C3WG44|2.A.123.2.3"
                     /protein_id="ABJ53972.1"
                     /translation="MIGSIAAILTTFAFLPQVFRVVKTKDTGSIALGMYVMQVIGIALW
                     LAHGIRIGDLPLILANSVSFLLSGIILFYKLKYK"
     gene            1858..2172
                     /locus_tag="SPD_0279"
     CDS             1858..2172
                     /locus_tag="SPD_0279"
                     /note="equivalent gene in S.pneumoniae TIGR4 = SP0305;
                     equivalent gene in S.pneumoniae R6 = spr0278; identified by
                     match to protein family HMM PF02302"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system, IIB component"
                     /protein_id="ABJ55373.1"
                     /translation="MAKALIICAAGMSSSLMAQKTTEFLKGKGKDIVVDAISATEGGKA
                     IAAAAFDLYLVSPQTKMYFKQFEEAGSKAGKPVVQIPPQAYIPIPMGIEKMANLILENI
                     "
     gene            2296..4269
                     /locus_tag="SPD_0280"
     CDS             2296..4269
                     /locus_tag="SPD_0280"
                     /note="equivalent gene in S.pneumoniae TIGR4 = SP0306;
                     equivalent gene in S.pneumoniae R6 = spr0279; identified by
                     match to protein family HMM PF00874; match to protein
                     family HMM PF05043"
                     /codon_start=1
                     /transl_table=11
                     /product="STP|HTH_11,STP|Mga"
                     /protein_id="ABJ54823.1"
                     /translation="MLNIKEKDILQFLIKNKERFVTSKELAEYLSCSDRTVRNVLKLIE
                     KTMIIQGVRLISKQGQGYQIFFENQGAYQEFRQTYELAEDYTKTAVSKGDDRLVFILNK
                     LLFEQVPVLFDDLADELYVSRSTLSHDFKKIRVMLSEYNLSIESRANKGVYVSGEERDK
                     RRFIINYFLENQFFKTIHCYVKFNFFDQTVPLEEFARIVLDECQEANLKLSDFVLQNLV
                     VHIALSVIRLKSGFEIKNIDCQMTDDAIERKVAQRILSKVREVTNQEFPVQEIDYITLH
                     LLAKSQQCQKNQKNISEEVLKKSLLKTFQNLGLDDMYNFSSDFQLIEGLITHLMTLQVR
                     LESRITLNNPLVDEIKQNYSDIFFMTREILANMDKFLEWSISDDEIAYVSLHFLAAMER
                     SKESTKFNILAICATGFGAAQMLRNRLETEFGNRVEVVDVIGYYELNQEKLKGIDFIVS
                     AVDLSNLYFQIPVFKVSVFLKSDEMEMIRKAMDQMQVSSHIQSSKISKFENNNFRQYFS
                     KENFLICTKYDKENLLEKMVEGLSVGESNEFEQSLLYGIKQREELSSVVFSEKIAVPHP
                     IQPFGTEGKVSIAICKDSLLWDNQSSHVQLVFLLSPSIYGNEGLATVTKKIVSLTENDE
                     LQNQLISCNNFEDFINIFEKIK"
     gene            4279..4593
                     /locus_tag="SPD_0281"
     CDS             4279..4593
                     /locus_tag="SPD_0281"
                     /EC_number="2.7.1.-"
                     /note="equivalent gene in S.pneumoniae TIGR4 = SP0308;
                     equivalent gene in S.pneumoniae R6 = spr0280; identified by
                     match to protein family HMM PF02255"
                     /codon_start=1
                     /transl_table=11
                     /product="gnl|TC-DB|P46319|4.A.3.2.2"
                     /protein_id="ABJ54026.1"
                     /translation="MNQEELQVAAFEIILHSGNARSEIHEAFAKMREGSFDDAESKLNQ
                     SNEIILEAHHAQTKLLQEYASGVEIKIEIIMVHAQDHLMTTMTLLEVAKEMLALYKKVN
                     "
     gene            4612..5118
                     /locus_tag="SPD_0282"
     CDS             4612..5118
                     /locus_tag="SPD_0282"
                     /note="equivalent gene in S.pneumoniae TIGR4 = SP0309;
                     equivalent gene in S.pneumoniae R6 = spr0281"
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein, putative"
                     /protein_id="ABJ53797.1"
                     /translation="MDRKERQKIEQQRREMALTNTFFNRYLLLRYSIALFFFGNIYWLL
                     NQFISPSLIIIFPIMLIVFSILATVEQFKLYGNRKEKLGITLMFVRIQMLISIGLLVLT
                     WTSWFTNLFPIFENNQVARLFVFVVLLLGLVLSLLDIRRIKKIYKRTDKAYQQFVQLEK
                     NSLRL"
     gene            5198..6544
                     /locus_tag="SPD_0283"
     CDS             5198..6544
                     /locus_tag="SPD_0283"
                     /note="equivalent gene in S.pneumoniae TIGR4 = SP0310;
                     equivalent gene in S.pneumoniae R6 = spr0282; identified by
                     match to protein family HMM PF02378; match to protein
                     family HMM TIGR00410"
                     /codon_start=1
                     /transl_table=11
                     /product="gnl|TC-DB|Q72XQ0|4.A.3.2.8"
                     /protein_id="ABJ54842.1"
                     /translation="MDQQNGLFGFLENHVMEPMGKLAQFKVVRAITAAGMAAVPFTIVG
                     SMFLVFSILPQAFSFWPIVADIFSASFGKFTSLYMVANYATMGSLSLYFVLSLAYELTK
                     IYAEEEELNMNPLNGSLLALMAFVMTVPQIIFDGGMMKAVTSLKEGAVIADGWAMGNGV
                     ARFGTTGIFTAIIMAIVTVLIYRMCVKNNWVIKMPEAVPEGVSRGFTALIPGFVVAFVV
                     IFINGLLVAMGTDIFKVIAIPFGFVSNLTNSWIGLMIIYLLTQLLWIVGIHGANIVFAF
                     VSPIALANMAENAAGGHFAVAGEFSNMFVIAGGSGATLGLCLYIAFASKSEQLKAIGRA
                     SVVPALFNINEPLIFGLPIIYNPALAIPFILAPMVTATIYYVANSLNFIKPIIAQVPWP
                     TPVGIGAFLGTADLRAVLVALVCAFAAFLVYLPFIRVYDQKLVKEEQGI"
ORIGIN
        1 atgactactt ttaaagatgg atttttatgg ggtggtgctg ttgctgctca tcaacttgaa
       61 ggtggatggc aagaaggtgg caagggaatt agtgttgctg atgttatgac tgctggtcgt
      121 catggagtag ctcgtgaaat tactttggga gttttagagg gtaaatatta tccaaatcat
      181 gaggcgatag atttttatca tcgttataaa gaagacatag cactttttgc tgaaatggga
      241 ttcaagtgct tccgtacctc tattgcatgg acacgtatct ttccaaaagg tgatgagtta
      301 gagccgaatg aagaaggatt acagttttat gataatcttt ttgatgaatg cttaaagaat
      361 ggtattgaac ctgtcatcac tctatctcat tttgaaatgc cttatcactt agtgaccgaa
      421 tatggtggtt ggaaaaatag gaaattgatt gatttctttg ctcgttttgc agaagtcgta
      481 tttaaacgtt acaaagataa ggttaaatat tggatgactt tcaatgaaat caataatcaa
      541 gcgaattatc aggaagattt tgcaccattt actaactcag gtattgtata tgaggaaggt
      601 gataatagag aagcaattat gtatcaagca gcacattacg aattagttgc ttctgcacga
      661 gctgtaaaaa ttggtcatga gattaatcca gattttcaaa taggttgtat gattgcgatg
      721 tgtccaattt atccagttac ttgcaatcct aaggatatct taatggcaat gaaagctatg
      781 cagaagcgtt attattttgc tgatgtgcat gttttaggta aatatcctga gcatattttc
      841 aagtattggg aacgaaaagg tatttcagtt gattttactg accaggataa agaagattta
      901 cttggtggga ctgtagatta cattggtttc agttactata tgtcctttgc tatagactct
      961 catcgtgaaa ataatcctta ttttgattat cttgaaacag aagatttagt gaaaaataat
     1021 tatgttaagg cttctgaatg ggagtggcaa attgatccag aaggtttacg ttatgcgtta
     1081 aattggttta cagaccacta tcacttacca ctctttattg ttgaaaatgg ttttggagct
     1141 atagatcaag ttgcagcaga tggtatggta catgatgatt atagaattga atatctaggt
     1201 gcccatattc gtgaaatgaa aaaggctgta gttgaagatg gtgttgattt aatgggttat
     1261 actccatggg gatgtattga tttggtttca gctggtaccg gtgaaatgcg gaaacgttat
     1321 ggctttattt atgtagataa agatgacaat gggaagggaa gttataatcg ttccccgaaa
     1381 aaatcttttg gctggtataa ggaagttatt tcatctaacg gtgaatcagt agaatagtat
     1441 aaacaaactg agattattct cagtttgttt agcatattga ggtgacatat gattggaagt
     1501 attgcagcaa ttttaacaac atttgcattt ttaccacaag tttttcgtgt agttaagaca
     1561 aaggacacag gatctattgc tctaggtatg tatgttatgc aagttattgg tattgcattg
     1621 tggcttgctc atggtattcg tataggagac ttgcctttga ttttagcaaa tagtgtttca
     1681 tttctactct caggaataat tttattttat aaattgaagt ataaataatt tttttccata
     1741 tcatttagga aaatgaggga attgtcattg gaaacgcttt attttataat aaaaatagat
     1801 aacaaataag ccaacttagc acagctttga ttggatttaa gaaaaggaga aaatattatg
     1861 gcaaaagctt taattatttg tgcagcagga atgtcttcat cacttatggc acagaaaaca
     1921 acagagtttc taaaaggaaa agggaaagat attgtagttg atgctattag tgctactgaa
     1981 ggagggaaag ctatcgcagc agcagctttt gatttgtatc ttgtcagccc tcaaacaaaa
     2041 atgtacttta agcaatttga agaggctggt tctaaagcag gaaaaccagt tgtacaaata
     2101 cctcctcaag catatattcc tattccaatg ggaattgaaa aaatggctaa tttgattctt
     2161 gagaatattt gatgaacaca tgaaatgtca ataaatattt aggttaagat aaattgtttt
     2221 gagtttgata taaactgatt taagtgtata atatgcttca atatatgaaa acatacgttt
     2281 taggagggaa tgaatgtgtt aaacattaaa gagaaagata tccttcaatt tttaataaaa
     2341 aataaggaac gttttgttac aagcaaagaa ctggcagaat atttatcctg ttcagataga
     2401 actgtccgta atgtactgaa attaattgag aagacaatga ttattcaagg agtccggttg
     2461 atttcaaaac aaggtcaagg gtatcaaata ttttttgaga atcaaggcgc ttatcaagag
     2521 tttagacaaa cttatgaact ggcagaagac tatacgaaaa ctgcggtttc aaaaggtgat
     2581 gatcgtttag tatttatctt aaataaatta ttatttgagc aagttccagt tctttttgat
     2641 gatttagctg atgaacttta cgttagtcgt tcaacattat ctcatgattt caaaaagata
     2701 cgagtgatgt tatcagagta taatttgtcc attgagagta gggcgaataa aggagtttat
     2761 gtctcaggcg aggaacgtga taaacgacgt tttatcataa attatttcct agagaatcaa
     2821 ttttttaaaa caatacattg ctatgtaaaa tttaactttt ttgatcaaac tgttccatta
     2881 gaagaatttg ctagaattgt tttggatgaa tgccaagagg ccaacctaaa actatctgat
     2941 tttgtactac agaatttagt agttcacata gcattgtctg tgattcgttt aaaatccgga
     3001 tttgaaataa aaaatataga ctgtcagatg actgatgatg caatagagag aaaggttgcc
     3061 caaagaattc tttctaaagt aagagaagta acaaatcagg aatttccagt tcaggaaata
     3121 gactacatta ctttgcattt gttagctaag agtcaacaat gtcaaaaaaa tcagaagaat
     3181 atttctgaag aagttttaaa aaaatcttta cttaaaacat ttcagaattt aggattagat
     3241 gatatgtata acttttcttc agatttccaa ctaattgaag gattgataac tcatctaatg
     3301 acactacaag tacgtttaga aagccggatt accttaaata accctttggt agatgaaatt
     3361 aaacagaatt atagtgatat attctttatg actagagaaa ttcttgcaaa tatggacaag
     3421 ttcttggagt ggtcaatatc agatgatgaa atagcatatg taagtcttca ctttttagct
     3481 gctatggaac gtagcaaaga gagtactaag tttaatattc ttgctatttg tgcaacggga
     3541 tttggtgcag cccaaatgtt aagaaatcgt ttggaaacgg agtttgggaa ccgagtagaa
     3601 gttgttgatg taataggcta ttatgaattg aatcaagaaa aacttaaagg aatagatttt
     3661 atagtgtcgg ctgttgattt atcaaatcta tattttcaaa ttccagtttt taaagttagt
     3721 gtatttctta agagtgatga gatggaaatg attcgcaaag ctatggatca gatgcaagtt
     3781 tcaagtcata tacaatcgtc aaagattagc aagtttgaaa acaacaactt tagacagtat
     3841 tttagtaaag aaaatttttt aatatgtact aaatatgaca aggaaaattt acttgaaaag
     3901 atggttgagg gtttatctgt tggtgaatca aatgagtttg aacaatcttt actttatgga
     3961 attaaacagc gagaagaatt aagttcagtt gttttttctg aaaaaattgc agttccgcat
     4021 cctattcaac cctttggtac agagggaaag gtttcgattg caatttgtaa agattcgtta
     4081 ctctgggata atcaaagttc acatgtccag ctagtatttc ttctatctcc atcaatatat
     4141 gggaacgaag gtttggcaac tgtgactaaa aagatagtct ctctgacaga gaatgatgaa
     4201 ttgcaaaatc agctaatatc ttgcaataac tttgaagatt ttattaacat atttgagaag
     4261 ataaaatagg aggttcatat gaatcaagag gaactgcagg ttgcagcatt tgaaattatc
     4321 ctgcattcgg gaaatgcaag gtcagaaata catgaagcat ttgcaaaaat gagagaaggt
     4381 agttttgatg atgcagaaag caaattaaat caatcaaatg agataattct tgaagcgcat
     4441 catgcacaaa ccaaactcct gcaagaatac gcaagtggag tggaaattaa aattgaaatt
     4501 atcatggtac atgctcaaga tcatttaatg accactatga cattattaga agtagcaaag
     4561 gaaatgttag ctctttataa gaaagttaac taaatataag gagggaatga tatggataga
     4621 aaagaacgac aaaaaattga acaacaacgt cgagagatgg ctctaactaa tacttttttc
     4681 aatcgatatc ttcttctacg ttattcaata gcactcttct tttttgggaa tatttattgg
     4741 cttttgaatc agtttattag tccctcgctt attattattt tccccattat gctcatagta
     4801 ttttctattt tagcaactgt tgaacaattt aaactttatg gaaataggaa agaaaagttg
     4861 ggaataacac taatgtttgt tagaatacaa atgcttattt caataggatt acttgtttta
     4921 acttggacaa gttggtttac gaatcttttt ccgatttttg aaaataacca agtagcacgt
     4981 ttatttgttt ttgtagttct tctattaggt ttagttctga gtttgttaga cattagaaga
     5041 attaaaaaaa tttataaacg aacagataag gcttatcaac aatttgtcca attggaaaag
     5101 aactcacttc gtttataatc ctgatctagt atcatttgta tttgaaacta gtcttcaaaa
     5161 agtaaaaatt attatgtttt attaaggagg tctatttatg gatcaacaaa acgggttgtt
     5221 tggtttcctt gaaaaccatg ttatggaacc aatgggcaaa cttgcccagt ttaaagtagt
     5281 acgtgctatc acggctgctg gtatggcagc tgtaccattt actattgtag gatcaatgtt
     5341 tttggtattc agtattttgc cacaagcttt ctcattttgg ccaattgtgg cagatatttt
     5401 ctctgcttca tttggtaaat tcacatcact ttacatggtt gcaaattatg cgactatggg
     5461 ttctctatct ctttattttg ttctttcact tgcatatgaa ttgacaaaaa tttatgcaga
     5521 ggaagaagaa ctcaatatga atcctcttaa tggttccttg cttgccttga tggcttttgt
     5581 catgacagta ccgcaaatca tttttgatgg tggaatgatg aaggctgtga caagtctaaa
     5641 agaaggcgca gtaattgcag atggatgggc aatgggaaat ggagtcgcac gttttgggac
     5701 aacagggatt tttaccgcaa tcattatggc aattgtgact gttcttattt atcgtatgtg
     5761 tgttaaaaat aattgggtta ttaaaatgcc tgaagctgtt ccagaaggag tttctcgtgg
     5821 atttaccgct ttgattccag gatttgttgt tgcattcgtt gttatcttta tcaacggtct
     5881 tcttgtagca atgggaacag atatttttaa agtcattgca attccatttg gttttgtatc
     5941 caatctgact aattcatgga ttggtttaat gattatttat ctgttgactc aactactttg
     6001 gattgtaggt atccacggtg cgaacattgt ttttgcattt gttagtccaa ttgctcttgc
     6061 taacatggct gaaaatgctg ctggcgggca cttcgctgtt gcaggtgaat tttctaatat
     6121 gtttgtaatt gcaggtggtt ctggtgcaac attaggccta tgtttatata ttgcttttgc
     6181 ctctaaatct gaacagctta aagcaatagg acgagcatct gtagttccag ccttatttaa
     6241 tattaatgaa ccattaattt ttggattacc tattatctat aatccagcct tggctatacc
     6301 atttatttta gcaccaatgg ttactgctac tatttattac gtagcgaatt ctctaaactt
     6361 tattaagcca attatcgcac aggttccatg gccaactcca gtagggattg gagctttctt
     6421 agggacagca gatcttcgag ctgtattagt tgctctcgtt tgtgcatttg cagcattctt
     6481 agtttatctc ccattcatcc gtgtatatga tcaaaaacta gtgaaagaag agcaaggtat
     6541 ctaa
//
