LOCUS       NC_002505               2714 bp    DNA     linear   CON 10-MAR-2020
DEFINITION  Vibrio cholerae O1 biovar El Tor str. N16961 chromosome I, complete
            sequence.
ACCESSION   NC_002505
VERSION     NC_002505.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN02603969
            Assembly: GCF_000006745.1
KEYWORDS    RefSeq.
SOURCE      Vibrio cholerae O1 biovar El Tor str. N16961
  ORGANISM  Vibrio cholerae O1 biovar El Tor str. N16961
            Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales;
            Vibrionaceae; Vibrio.
REFERENCE   1  (bases 1 to 2714)
  AUTHORS   Heidelberg,J.F., Eisen,J.A., Nelson,W.C., Clayton,R.A., Gwinn,M.L.,
            Dodson,R.J., Haft,D.H., Hickey,E.K., Peterson,J.D., Umayam,L.,
            Gill,S.R., Nelson,K.E., Read,T.D., Tettelin,H., Richardson,D.,
            Ermolaeva,M.D., Vamathevan,J., Bass,S., Qin,H., Dragoi,I.,
            Sellers,P., McDonald,L., Utterback,T., Fleishmann,R.D.,
            Nierman,W.C., White,O., Salzberg,S.L., Smith,H.O., Colwell,R.R.,
            Mekalanos,J.J., Venter,J.C. and Fraser,C.M.
  TITLE     DNA sequence of both chromosomes of the cholera pathogen Vibrio
            cholerae
  JOURNAL   Nature 406 (6795), 477-483 (2000)
   PUBMED   10952301
REFERENCE   2  (bases 1 to 2714)
  AUTHORS   Heidelberg,J.F., Eisen,J.A., Nelson,W.C., Clayton,R.A., Gwinn,M.L.,
            Dodson,R.J., Haft,D.H., Hickey,E.K., Peterson,J.D., Umayam,L.A.,
            Gill,S.R., Nelson,K.E., Read,T.D., Tettelin,H., Richardson,D.,
            Ermolaeva,M.D., Vamathevan,J., Bass,S., Qin,H., Dragoi,I.,
            Sellers,P., McDonald,L., Utterback,T., Fleishmann,R.D.,
            Nierman,W.C., White,O., Salzberg,S.L., Smith,H.O., Colwell,R.R.,
            Mekalanos,J.J., Venter,J.C. and Fraser,C.M.
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2000) The Institute for Genomic Research, 9712
            Medical Center Dr, Rockville, MD 20850, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 03/10/2020 04:57:55
            Annotation Pipeline               :: NCBI Prokaryotic Genome
            Annotation Method                 :: Best-placed reference protein
            Annotation Software revision      :: 4.11
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
            Genes (total)                     :: 3,735
            CDSs (total)                      :: 3,608
            Genes (coding)                    :: 3,527
            CDSs (with protein)               :: 3,527
            Genes (RNA)                       :: 127
            rRNAs                             :: 9, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 98
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 64 of 81
            Pseudo Genes (incomplete)         :: 12 of 81
            Pseudo Genes (internal stop)      :: 9 of 81
            Pseudo Genes (multiple problems)  :: 3 of 81
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence was derived from
            AE003852.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Annotation Pipeline (PGAP)
            set; GeneMarkS-2+
            repeat_region
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..2714
                     /organism="Vibrio cholerae O1 biovar El Tor str. N16961"
                     /mol_type="genomic DNA"
                     /strain="N16961"
                     /serotype="O1"
                     /db_xref="taxon:243277"
                     /chromosome="I"
                     /biotype="El Tor"
     gene            13..723
                     /locus_tag="VC_RS08595"
                     /old_locus_tag="VC1781"
                     /old_locus_tag="VC_1781"
                     /db_xref="GeneID:2613661"
     CDS             13..723
                     /locus_tag="VC_RS08595"
                     /old_locus_tag="VC1781"
                     /old_locus_tag="VC_1781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005470000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="WP_001230630.1"
                     /db_xref="GeneID:2613661"
                     /translation="MRKNFLNIEELKRFLNGQTVVSIQPVTGSPLDKTDFIVAMAIAVE
                     QAGAKALRIEGVNNVAAVSAAVTIPIIGIVKRDLPDSPIRITPFVSDVDGLANAGATVI
                     AFDATDRTRPESRERIAQAIKNTGCFAMADCSTFEDGLWANSQGVEIVGSTLSGYVGDI
                     EPTVPDFQLVKAFSEAGFFTMAEGRYNTPELAAKAIESGAVAVTVGSALTRLEVVTQWF
                     NNATQAAGERKCAH"
     gene            711..1574
                     /locus_tag="VC_RS08600"
                     /old_locus_tag="VC1782"
                     /old_locus_tag="VC_1782"
                     /db_xref="GeneID:2613662"
     CDS             711..1574
                     /locus_tag="VC_RS08600"
                     /old_locus_tag="VC1782"
                     /old_locus_tag="VC_1782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005524639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="STP|Glucokinase"
                     /protein_id="WP_001259414.1"
                     /db_xref="GeneID:2613662"
                     /translation="MRTLAIDIGGTKIALAIVEEGTIIQRYQIATPVVQDVTKFVQAIL
                     EKVTEWLPSIDYVGVSTTGYVTPEGITSINPETLNFPVPFPLAQTLEQLTNKPVSILND
                     AQAAAWFEFVQLKNPSLNMAFITVSTGVGGGIIIDGKLHKGNSGLAGHIGHMSVAIEGP
                     LCGCGQRGCVESMASGNAIQKESEATFTETMSNVELFKQAAFNPKAEAIINRSVQAVAT
                     LCCNLKACLDLDIIVLGGGIGLAEGYLERLNKAIQSRPSVFHIPVTPAHGDYDACLLGA
                     AFQFKE"
     gene            1578..2714
                     /gene="nagA"
                     /locus_tag="VC_RS08605"
                     /old_locus_tag="VC1783"
                     /old_locus_tag="VC_1783"
                     /db_xref="GeneID:2613663"
     CDS             1578..2714
                     /gene="nagA"
                     /locus_tag="VC_RS08605"
                     /old_locus_tag="VC1783"
                     /old_locus_tag="VC_1783"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001185232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CE9"
                     /protein_id="WP_001185226.1"
                     /db_xref="GeneID:2613663"
                     /translation="MALKAISATRLFDGIQYYENAAMVWEGSHIHSIVPIESLTEDIEH
                     QHFDGALIAPGFIDLQVNGGGDVMFNNDMTLAGIDSICRAHRTHGTAYLLPTLISATPE
                     HINRALDAIQSAIENQVSGVLGIHLEGPWLNPEKKGAHNPDLFYSPTPEQLSQFHWPTK
                     GKVLVTVAAENLSIDSLKWLKDHHVTLSCGHSNATTAQLTTEKLALIDGFTHLFNAMSP
                     FESREPGVVGTALNTDHAWCSVITDGIHVHPQSFLLAKRIKPKDKLLIVTDAMASLGSV
                     TSQFELDGETIRVIDNKLINSRGNLAGAHIGMDESVANVIRWGIAEDEALKMASSYPAQ
                     AIQCDDLGQLKPNYRAAATVLNSKYESLAVVSEGVLYN"
ORIGIN
        1 atgaggcccg tcgtgagaaa gaattttttg aatatcgaag agttaaagcg atttttaaac
       61 ggccaaactg tcgtttccat acaacctgta acaggcagcc cactcgataa aacagatttc
      121 attgtggcga tggcgatcgc cgtcgaacaa gcgggtgcaa aagcgctgcg cattgaaggt
      181 gtgaataacg tggctgctgt atccgccgca gtaacaattc cgattatagg tatcgttaag
      241 cgtgacttgc ctgatagccc aattcgaatc actccttttg tttcagatgt tgatggctta
      301 gcaaatgctg gcgcaacggt cattgctttt gatgccaccg atagaacacg ccctgaaagt
      361 cgagaacgta ttgcgcaagc aatcaaaaac acgggatgtt ttgcgatggc cgattgctcc
      421 acattcgagg atggattatg ggctaactca caaggtgttg aaattgttgg atcaacactg
      481 tcaggctatg tcggagatat tgagcccacg gttccagatt tccaacttgt gaaagcgttt
      541 tctgaagccg gcttttttac catggcggaa ggtcgataca atacgcctga gttagcagcg
      601 aaagctattg agtctggtgc ggttgccgta acggttggtt ctgcattgac tcgattagaa
      661 gtggttactc aatggttcaa taacgcaacc caagctgcgg gagaaaggaa atgcgcacac
      721 tagccatcga tatcggcgga acaaaaatag cattagcgat tgtagaagaa ggtacgatca
      781 tacagcgtta ccagatagca acgcctgtgg tgcaggacgt caccaagttt gttcaagcga
      841 ttctcgaaaa ggtcactgaa tggctccctt ctatcgatta tgtaggcgta tcaacaacag
      901 gttatgtaac gccagaaggc atcacatcga taaatccaga gactcttaat ttccctgtac
      961 cttttccatt agctcaaacg ctagaacaac tcactaataa accagtctcc attcttaatg
     1021 atgcacaggc cgcggcatgg tttgaatttg tgcagttaaa aaatcctagc ttaaatatgg
     1081 cttttattac ggtttcaaca ggggttggtg gcggaatcat cattgatggc aagcttcaca
     1141 aaggaaacag cggtttagcg ggacacatag gtcacatgtc ggtggccatt gaaggtccat
     1201 tatgcggatg tggtcagcga ggttgtgttg agtccatggc ttcaggtaac gcgattcaaa
     1261 aagagagcga agccactttt accgagacaa tgagcaatgt tgagttattt aagcaagcag
     1321 cgttcaaccc gaaagcagaa gcgatcatca atcgcagtgt gcaagcagta gccacattat
     1381 gctgtaatct taaagcatgc ttagatctgg atattattgt tttgggtggt ggaattggtc
     1441 tcgcagaggg ctaccttgaa cgcctcaaca aagctattca atctaggcca tccgtatttc
     1501 acatccctgt cactcctgct catggcgatt atgatgcttg cctactcgga gcagcatttc
     1561 agtttaagga gtaaacgatg gcattaaagg caatttcagc cacacggctt tttgatggaa
     1621 ttcagtatta cgagaatgcg gcaatggttt gggaaggttc acacattcac tccattgttc
     1681 ctattgagtc tctgacggag gatattgagc atcaacattt tgatggtgca ttgatcgctc
     1741 caggattcat tgacttacaa gttaatggcg gtggcgatgt catgttcaat aatgacatga
     1801 ctcttgcggg tattgattcg atctgccgag cacacagaac tcacggcacc gcctatctgc
     1861 ttccaacctt aatcagtgca acaccggaac acatcaaccg tgcacttgat gccattcaat
     1921 ctgcaatcga aaatcaagtc tcgggtgtgt tgggtattca cttagagggg ccttggttaa
     1981 acccagaaaa gaaaggcgct cataacccag atctgttcta ttccccgaca cccgaacaac
     2041 tttcacagtt tcactggcca accaaaggca aagttcttgt aacggtcgcg gctgaaaacc
     2101 tctccatcga ctcactaaag tggttaaagg atcatcatgt tactctctcg tgtggtcaca
     2161 gtaatgccac tacagcccaa ttaaccactg agaagttagc tctcattgat ggatttaccc
     2221 acttatttaa tgccatgtcg ccttttgaga gtcgtgaacc cggagttgtc ggtacagcat
     2281 tgaataccga tcatgcttgg tgttcagtaa taactgatgg aattcatgtc catccacaaa
     2341 gttttttact cgctaagcga atcaaaccta aagacaaact tcttattgtt accgatgcca
     2401 tggctagcct tggcagtgtg actagccagt ttgaattgga tggggaaacc attcgcgtca
     2461 tcgataataa actgattaat agcagaggca atcttgcggg agcacacatc gggatggatg
     2521 aatcggttgc caatgttatt cgttggggaa tcgcggaaga tgaagcatta aaaatggcct
     2581 cgtcttatcc ggctcaagca attcaatgtg atgatttagg gcaactaaaa cccaattatc
     2641 gagccgccgc cactgtatta aactccaaat atgaaagctt ggctgtagtc agtgaaggcg
     2701 tgctctacaa ctga
//
