LOCUS       NC_002505               4394 bp    DNA     linear   CON 10-MAR-2020
DEFINITION  Vibrio cholerae O1 biovar El Tor str. N16961 chromosome I, complete
            sequence.
ACCESSION   NC_002505
VERSION     NC_002505.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN02603969
            Assembly: GCF_000006745.1
KEYWORDS    RefSeq.
SOURCE      Vibrio cholerae O1 biovar El Tor str. N16961
  ORGANISM  Vibrio cholerae O1 biovar El Tor str. N16961
            Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales;
            Vibrionaceae; Vibrio.
REFERENCE   1  (bases 1 to 4394)
  AUTHORS   Heidelberg,J.F., Eisen,J.A., Nelson,W.C., Clayton,R.A., Gwinn,M.L.,
            Dodson,R.J., Haft,D.H., Hickey,E.K., Peterson,J.D., Umayam,L.,
            Gill,S.R., Nelson,K.E., Read,T.D., Tettelin,H., Richardson,D.,
            Ermolaeva,M.D., Vamathevan,J., Bass,S., Qin,H., Dragoi,I.,
            Sellers,P., McDonald,L., Utterback,T., Fleishmann,R.D.,
            Nierman,W.C., White,O., Salzberg,S.L., Smith,H.O., Colwell,R.R.,
            Mekalanos,J.J., Venter,J.C. and Fraser,C.M.
  TITLE     DNA sequence of both chromosomes of the cholera pathogen Vibrio
            cholerae
  JOURNAL   Nature 406 (6795), 477-483 (2000)
   PUBMED   10952301
REFERENCE   2  (bases 1 to 4394)
  AUTHORS   Heidelberg,J.F., Eisen,J.A., Nelson,W.C., Clayton,R.A., Gwinn,M.L.,
            Dodson,R.J., Haft,D.H., Hickey,E.K., Peterson,J.D., Umayam,L.A.,
            Gill,S.R., Nelson,K.E., Read,T.D., Tettelin,H., Richardson,D.,
            Ermolaeva,M.D., Vamathevan,J., Bass,S., Qin,H., Dragoi,I.,
            Sellers,P., McDonald,L., Utterback,T., Fleishmann,R.D.,
            Nierman,W.C., White,O., Salzberg,S.L., Smith,H.O., Colwell,R.R.,
            Mekalanos,J.J., Venter,J.C. and Fraser,C.M.
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2000) The Institute for Genomic Research, 9712
            Medical Center Dr, Rockville, MD 20850, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 03/10/2020 04:57:55
            Annotation Pipeline               :: NCBI Prokaryotic Genome
            Annotation Method                 :: Best-placed reference protein
            Annotation Software revision      :: 4.11
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
            Genes (total)                     :: 3,735
            CDSs (total)                      :: 3,608
            Genes (coding)                    :: 3,527
            CDSs (with protein)               :: 3,527
            Genes (RNA)                       :: 127
            rRNAs                             :: 9, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 98
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 64 of 81
            Pseudo Genes (incomplete)         :: 12 of 81
            Pseudo Genes (internal stop)      :: 9 of 81
            Pseudo Genes (multiple problems)  :: 3 of 81
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence was derived from
            AE003852.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Annotation Pipeline (PGAP)
            set; GeneMarkS-2+
            repeat_region
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..4394
                     /organism="Vibrio cholerae O1 biovar El Tor str. N16961"
                     /mol_type="genomic DNA"
                     /strain="N16961"
                     /serotype="O1"
                     /db_xref="taxon:243277"
                     /chromosome="I"
                     /biotype="El Tor"
     gene            complement(1..1215)
                     /locus_tag="VC_RS04905"
                     /old_locus_tag="VC0993"
                     /old_locus_tag="VC_0993"
                     /db_xref="GeneID:2614246"
     CDS             complement(1..1215)
                     /locus_tag="VC_RS04905"
                     /old_locus_tag="VC0993"
                     /old_locus_tag="VC_0993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005599340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DBD-Pfam|MarR,DBD-SUPERFAMILY|0040517"
                     /protein_id="WP_001013120.1"
                     /db_xref="GeneID:2614246"
                     /translation="MNGGQIGNVDLVKQLNSAAVYRLIDQQGPISRIQVADVSQLAPAS
                     VTKITRQLLERGLIKEVAQQASTGGRRAISLTTEVKPFHSIAVRIGRDYIQLSLYDLGG
                     NSLVDEHHEFHYNTQDVLMSSLIKQIKQFIQQHTALIDQLIAIGVALPGLVNPETGVVE
                     YMPNVAINELPLGATIRDEFHVECFVGNDVRGIALAEHYFGASQDCQDSILVSVHRGTG
                     AGIIVNGQVFLGYNRNVGEIGHIQIDPLGEQCQCGNFGCLETVATNPAITSRVQKLIAQ
                     GYESSLSTLDTITIDDVCEHANAGDELAKQALVRVGNQLGKAIAITVNLFNPQKIVIAG
                     QITAAKEIVFPAIQRNVENQSLKTFHQHLPIVSSQVYKQPTMGAFAMIKRAMLNGVLLQ
                     KLLED"
     gene            complement(1218..2354)
                     /gene="nagA"
                     /locus_tag="VC_RS04910"
                     /old_locus_tag="VC0994"
                     /old_locus_tag="VC_0994"
                     /db_xref="GeneID:2614247"
     CDS             complement(1218..2354)
                     /gene="nagA"
                     /locus_tag="VC_RS04910"
                     /old_locus_tag="VC0994"
                     /old_locus_tag="VC_0994"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001964282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CE9"
                     /protein_id="WP_000271133.1"
                     /db_xref="GeneID:2614247"
                     /translation="MYALTNCKIYTGNDVLVKHAVIINGDKIEAVCPIESLPSEMNVVD
                     LNGANLSPGFIDLQLNGCGGVMFNDEITAETIDTMHKANLKSGCTSFLPTLITSSDENM
                     RQAIAAAREYQAKYPNQSLGLHLEGPYLNVMKKGIHSVDFIRPSDDTMIDTICANSDVI
                     AKVTLAPENNKPEHIEKLVKAGIVVSIGHTNATYSEARKSFESGITFATHLFNAMTPMV
                     GREPGVVGAIYDTPEVYAGIIADGFHVDYANIRIAHKIKGEKLVLVTDATAPAGAEMDY
                     FIFVGKKVYYRDGKCVDENGTLGGSALTMIEAVQNTVEHVGIALDEALRMATLYPAKAI
                     GVDEKLGRIKKGMIANLTVFDRDFNVKATVVNGQYEQN"
     gene            2823..4394
                     /locus_tag="VC_RS04915"
                     /old_locus_tag="VC0995"
                     /old_locus_tag="VC_0995"
                     /db_xref="GeneID:2614248"
     CDS             2823..4394
                     /locus_tag="VC_RS04915"
                     /old_locus_tag="VC0995"
                     /old_locus_tag="VC_0995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002043566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gnl|TC-DB|P09323|4.A.1.1.2"
                     /protein_id="WP_001023164.1"
                     /db_xref="GeneID:2614248"
                     /translation="MNILGYAQKLGKALMLPIATLPVAALLLRLGQPDLLGIPFMAAAG
                     DAIFSQLPLLFGLGIAIGLSKDGSGAAGLAGAVAYFVLSATAKTIDASINMSFFGGIFA
                     GIIAGHSYNAFHTTRLPEWLAFFAGKRLVPIMAGLFALVAGALSGVIWPSIQGGLDALA
                     HAVSTSGALGQFVYGTLNRALIPVGLHHVLNSYFWFGMGTCQEILVSGAQAAGQALPAL
                     EKLCVDPALAKTLVVGQEHTFAFKNAVTPEITAVVKEVTEVVKSGDLHRFFGGDKSAGV
                     FMNGFFPVMMFGLPGAALAMYLAAPAERRHQVGGALFSVAFCSFLTGITEPLEFMFVFL
                     APALYAMHAVFTGLSLVVANMFGTLHGFGFSAGLIDFLLNWGLATKPATLFVIGLAFFA
                     LYFFTFTFAIRAFNLKSPGREDEEVETETDSADASKGDLARQYLKALGGHENLTSIDAC
                     ITRLRLTLKDRSVADEAVLKKLGAKGVVKLGENNLQVILGPLAEIVAGEMKAISPKEDL
                     SDVKLP"
ORIGIN
        1 tcagtcttca agcaattttt gtaacagaac cccatttaac atcgcacgtt tgatcatagc
       61 aaaagcgccc atagtgggtt gtttgtagac ttgtgaagac acaatcggca gatgttggtg
      121 gaacgttttc agtgactgat tttctacgtt gcgttgaatc gcggggaaca cgatctcttt
      181 ggcggcggtg atttgcccag caatcacgat cttttgtggg ttgaataggt ttacggtaat
      241 cgcaatcgcc ttacccaact gattacctac acgaaccaac gcttgtttcg ccagttcatc
      301 cccagcattt gcgtgctcac agacatcatc aatcgtaatc gtatcgagag tagagagcga
      361 agattcatac ccctgagcga tcagtttttg cacacgagaa gtgatagcag ggttggtcgc
      421 aacggtttct agacaaccaa agttgccaca ttgacattgc tcaccaagag ggtcgatttg
      481 gatgtggcca atttcaccga cgttgcggtt atagcctaag aagacttgac cgttaacgat
      541 aatccctgca cctgtgccac ggtgtacact gactagtatg gagtcttggc aatcttggct
      601 tgctccgaaa tagtgctccg ctaaggcaat accacgaacg tcgttaccca caaaacattc
      661 aacatggaac tcatcacgaa tggttgcgcc gagaggtaat tcattgatcg cgacattagg
      721 catgtactca acaacacctg tttctgggtt caccaaaccg ggtaaggcca caccaatcgc
      781 aatcaactga tcaattaatg cggtgtgttg ttgaataaat tgtttgatct gtttaatcag
      841 gctcgacatc aacacgtctt gcgtgttgta gtgaaattca tgatgctcat caaccagtga
      901 gtttccacct aggtcataga ggctgagttg aatatagtca cgtccgatac gcacggcaat
      961 agagtggaac ggcttgactt ctgtggtcag cgaaatggct cgccgaccac ctgtagaagc
     1021 ttgttgcgcg acttctttga ttaatccacg ttcaagcaat tggcgggtaa tcttggtaac
     1081 actggccgga gccagttggc ttacatcagc gacttgaatc cgactgattg ggccttgttg
     1141 gtcaatcaag cggtaaaccg ccgcactgtt tagctgttta actaaatcta cgttaccaat
     1201 ctgtccgcca ttcattatca attctgctcg tattgtccgt taactaccgt cgcttttacg
     1261 ttgaagtcac gatcaaaaac agtcaggttg gcgatcatac ctttcttgat acgaccgagt
     1321 ttctcatcaa caccgattgc tttcgctgga tacagagtag ccattcgcag agcttcatct
     1381 aaagcgatac cgacatgctc aaccgtattt tgaactgctt caatcattgt tagggctgaa
     1441 ccgccaagcg tgccattttc atcaacacat ttgccatctc ggtaatatac tttcttaccg
     1501 acaaaaataa agtaatccat ttcagcgcct gcaggagctg tggcatcggt cactaatacg
     1561 agcttttcac ccttaatttt gtgggcaatt cggatgtttg cgtaatcaac atggaagcca
     1621 tcggcgatga tgcccgcata cacctcaggt gtatcataaa tcgccccgac cactcctggt
     1681 tcacgaccta ccatcggggt cattgcgtta aagaggtggg tcgcaaaggt aatgccggat
     1741 tcaaagcttt tacgtgcttc gctataggtc gcgtttgtgt gtccaatgga aacaacaatt
     1801 cccgctttaa ccagcttctc aatatgttca ggcttattat tttctggcgc gagagtgact
     1861 ttggcgatca catcactatt ggcacaaatc gtatcaatca tcgtatcgtc agaggggcgg
     1921 atgaagtcaa cgctgtggat cccttttttc atgacattca gataaggccc ttctaaatga
     1981 agaccaagcg attgatttgg gtatttagcc tgatattcgc gagcggcggc aattgcttgg
     2041 cgcatgttct catcggaaga agtgatcagc gttggaagga agctggtaca gcccgattta
     2101 aggttagctt tgtgcatggt atcgatggtt tccgctgtga tttcatcatt gaacatcaca
     2161 ccaccacagc cattcagctg taaatcgata aaaccagggc tgaggtttgc accgtttagg
     2221 tcgaccacat tcatctcaga tggaagagat tcgatagggc aaacggcttc aattttgtca
     2281 ccgttgatga ttaccgcatg tttcacaagc acatcattgc ctgtgtagat tttgcagttc
     2341 gttagcgcat acataatcag ctaatcctct tgtcgatatt tttagattca ttttagcgac
     2401 tcaccgaggt tacagccaaa gcgcaagctg cttcacttca atcaggtcgc gaattatctt
     2461 ttgtgcaaaa ggccacagca actgcggcta aaaataagtc attggtcaat ccactcttcg
     2521 cggtgtttaa cctaagggca ttaagagaaa tgcactatgt taacgagtgt aacacggtga
     2581 ctgtctgacc aacaaacgct gtaatattag cgtccaaaag ttgttttttt acatcataaa
     2641 ataagtttta tgatctggct agcaaaatca tttcgttctt agaaccacgg gtgattagga
     2701 tcacaaatga tgaggtttta atttgcggag caaaattaat gtcataaact gaccaggact
     2761 aaattgggcg actaaaaaaa gtctctcaat actatacaaa aatcctatag ggggaactta
     2821 aggtgaatat tcttggatat gcgcaaaagt taggtaaagc attgatgcta cctatcgcta
     2881 cgctacctgt agcggcgctc ttacttcgtt taggtcaacc agacctgtta ggcattccat
     2941 tcatggctgc agcgggcgat gcaattttta gccagctgcc actactgttt ggtttgggta
     3001 ttgccattgg tttatcgaaa gatggatctg gcgccgcagg tctagcgggt gcagtagctt
     3061 actttgttct gagtgcaacg gcaaaaacga ttgatgcttc aatcaacatg tctttctttg
     3121 gcggtatctt cgcaggtatc atcgcagggc actcttacaa cgcgttccac actacacgtc
     3181 tgccagagtg gctagcattc tttgctggta agcgtttagt gccaattatg gcgggtctgt
     3241 tcgctctggt tgctggtgcg ctttctggcg ttatctggcc atcaattcaa ggtggattag
     3301 atgcgctggc gcatgccgtc tctacatcag gtgctttagg ccaatttgtt tacggtactc
     3361 tgaaccgtgc tctgatccct gtaggtttac accacgttct gaactcttac ttctggttcg
     3421 gcatgggtac ctgtcaagag atcctagttt caggtgctca agccgctggt caagcactgc
     3481 ctgcactcga aaaactgtgt gtggatccag ctctagcgaa aaccctagtt gtgggtcaag
     3541 agcatacttt tgcgttcaaa aatgcggtaa cgcctgaaat cacagctgtg gtaaaagaag
     3601 tgactgaagt ggttaaatct ggcgacctac accgtttctt cggtggcgat aagagcgctg
     3661 gggtattcat gaacggcttc ttccctgtca tgatgttcgg tctaccaggt gctgcacttg
     3721 ctatgtacct agccgctcca gctgagcgtc gtcaccaagt gggtggtgca ctgttctctg
     3781 ttgcgttctg ttcattccta acaggtatca ctgagcctct agagttcatg tttgtgttcc
     3841 tagcacctgc gctgtatgca atgcatgcgg tatttacagg tctgtcactg gttgtggcta
     3901 acatgtttgg cacactgcat ggtttcggtt tctcagcagg tcttatcgac ttcctgttga
     3961 actggggtct agcaacgaaa cctgcaactc tgtttgtgat tggtctggcg ttctttgctc
     4021 tgtacttctt tacgttcaca ttcgccattc gtgcgttcaa cctgaaatct ccaggtcgtg
     4081 aagacgaaga agtggaaaca gaaacagact ccgctgatgc atctaaaggt gatttggctc
     4141 gccaatacct gaaagcactg ggtggtcatg aaaacctgac atctatcgat gcgtgcatca
     4201 cacgtctacg tctgactctg aaagaccgct ctgttgcaga tgaagcggta ctgaagaaac
     4261 tgggcgcgaa aggtgttgtg aaactgggtg aaaataacct gcaagttatc cttggccctc
     4321 tagcagaaat cgtcgcgggt gagatgaaag ccatcagccc gaaagaagat ctttctgacg
     4381 ttaaactgcc ttaa
//
