LOCUS       NC_010572               6166 bp    DNA     linear   CON 10-FEB-2020
DEFINITION  Streptomyces griseus subsp. griseus NBRC 13350, complete sequence.
ACCESSION   NC_010572
VERSION     NC_010572.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMD00060929
            Assembly: GCF_000010605.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces griseus subsp. griseus NBRC 13350
  ORGANISM  Streptomyces griseus subsp. griseus NBRC 13350
            Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae;
            Streptomyces.
REFERENCE   1
  AUTHORS   Ohnishi,Y., Ishikawa,J., Hara,H., Suzuki,H., Ikenoya,M., Ikeda,H.,
            Yamashita,A., Hattori,M. and Horinouchi,S.
  TITLE     Genome sequence of the streptomycin-producing microorganism
            Streptomyces griseus IFO 13350
  JOURNAL   J. Bacteriol. 190 (11), 4050-4060 (2008)
   PUBMED   18375553
REFERENCE   2
  AUTHORS   Funabashi,M., Funa,N. and Horinouchi,S.
  TITLE     Phenolic lipids synthesized by type III polyketide synthase confer
            penicillin resistance on Streptomyces griseus
  JOURNAL   J. Biol. Chem. 283 (20), 13983-13991 (2008)
   PUBMED   18364359
  REMARK    Erratum:[J Biol Chem. 2008 Sep 5;283(36):25104]
REFERENCE   3
  AUTHORS   Hirano,S., Tanaka,K., Ohnishi,Y. and Horinouchi,S.
  TITLE     Conditionally positive effect of the TetR-family transcriptional
            regulator AtrA on streptomycin production by Streptomyces griseus
  JOURNAL   Microbiology (Reading, Engl.) 154 (Pt 3), 905-914 (2008)
   PUBMED   18310036
REFERENCE   4  (bases 1 to 6166)
  AUTHORS   Hattori,M., Ohnishi,Y., Yamashita,A., Ishikawa,J., Ikeda,H. and
            Horinouchi,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2007) Contact:Masahira Hattori Graduate School of
            Frontier Sciences, The University of Tokyo; Kashiwanoha 5-1-5,
            Kashiwa, Chiba 277-8561, Japan URL
            :http://www.cb.k.u-tokyo.ac.jp/hattorilab/
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 02/10/2020 02:00:57
            Annotation Pipeline               :: NCBI Prokaryotic Genome
            Annotation Method                 :: Best-placed reference protein
            Annotation Software revision      :: 4.11
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
            Genes (total)                     :: 7,167
            CDSs (total)                      :: 7,079
            Genes (coding)                    :: 6,935
            CDSs (with protein)               :: 6,935
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 67
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 74 of 144
            Pseudo Genes (incomplete)         :: 97 of 144
            Pseudo Genes (internal stop)      :: 11 of 144
            Pseudo Genes (multiple problems)  :: 35 of 144
            CRISPR Arrays                     :: 3
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence was derived from
            AP009493.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            The complete and fully annotated sequences are also available at
            http://park.itc.u-tokyo.ac.jp/hakko/genome/
            Annotation Pipeline (PGAP)
            set; GeneMarkS-2+
            repeat_region
FEATURES             Location/Qualifiers
     source          1..6166
                     /organism="Streptomyces griseus subsp. griseus NBRC 13350"
                     /mol_type="genomic DNA"
                     /strain="NBRC 13350"
                     /sub_species="griseus"
                     /db_xref="taxon:455632"
                     /note="synonym: Streptomyces griseus subsp. griseus IFO
                     13350"
     gene            1..1323
                     /locus_tag="SGR_RS23570"
                     /old_locus_tag="SGR_4735"
                     /db_xref="GeneID:6209155"
     CDS             1..1323
                     /locus_tag="SGR_RS23570"
                     /old_locus_tag="SGR_4735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014672903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gnl|TC-DB|Q9X9R7|3.A.1.1.23"
                     /protein_id="WP_012380827.1"
                     /db_xref="GeneID:6209155"
                     /translation="MRITRSVAGRRRRTALVATTGLTVTALLLTGCGGSSDSDKGADAD
                     GNITLTLADFGQFGYKEAGLFEKYHELNPKITVKEDTTAEEKNYYPKLLQQLNSGSGLA
                     DVQGIEVGRIKEIVDTKADSFADLSQTIGVDEWVSWKAKQATAPSGAVIGAGTDIGPMS
                     LCYNRELFEKAGLPTDRAEVAKLTEGGWEDFLALGEQYKKKAPEGTYFMDSASAMFNAV
                     VSSSPEQYYDASGKPVYETSASVEKGWKLAAEAASKKLTQGLAQFEDQWQAALRKSTVA
                     TVVCPAWMAGQISTYAGDANKGKWDITSAPGNTSANWGGSFLAVPKSGKNVAEATKLVR
                     WLTAPEQQAAVFKAIGVFPSNQGAYELPDVKNATLPYFNNAPIGQIYADGAKSIPEAVL
                     GPKDGVIKDSISTQINNMEQRGTSPDDAWDAAVRTIDKAIG"
     gene            1492..2490
                     /locus_tag="SGR_RS23575"
                     /old_locus_tag="SGR_4736"
                     /db_xref="GeneID:6214400"
     CDS             1492..2490
                     /locus_tag="SGR_RS23575"
                     /old_locus_tag="SGR_4736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018518043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gnl|TC-DB|Q9X9R6|3.A.1.1.23"
                     /protein_id="WP_012380828.1"
                     /db_xref="GeneID:6214400"
                     /translation="MATSTPTRDAYATPPREPKKEPPSERRQLWRSRLWRFDDKASPYA
                     YIAPFFLVFGAFGLYPLLYTGWIALHRVEMTGLDSMEWVGWENFDKILHDPEFWTSVSN
                     TFLIGVISTVPQLLVALGLAHLLNYKLRASTFWRTVILTPYATSVASAALVFALVFRAD
                     GGLLNWTLGLVGFDPVNWANGHWTSKLAISIIVIWRWTGYNALIYLAAMQAVPNDLYEA
                     ASLDGASRWQQFRKVTIPSLRPTILFTIVISTIGSMQLFGEPLLLEGGALGATGGNENQ
                     YETLSIYLYNYGWNLGHLGPAAAVAWAMLALLLIIAAANWFIGRFVRKSAV"
     gene            2505..3425
                     /locus_tag="SGR_RS23580"
                     /old_locus_tag="SGR_4737"
                     /db_xref="GeneID:6214401"
     CDS             2505..3425
                     /locus_tag="SGR_RS23580"
                     /old_locus_tag="SGR_4737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014672901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gnl|TC-DB|Q9X9R5|3.A.1.1.23"
                     /protein_id="WP_012380829.1"
                     /db_xref="GeneID:6214401"
                     /translation="MTLTSPTHPAPVKLAPAPQGGAPRRPSRFRMGAGQQLKGGPFAYI
                     ALAVVGFGSLLPLYWTLVAASRTQDEVLAATPPFLPGGKLLENLQTAWEQANLGTAILN
                     SVIVSSSITLATLFFCTLAGYAFAKMRFRGRGWLMTAVIATLTIPPQLSVVPLFMMMSG
                     LGWGGQLESVIFPTLVSAFGVFFMRQYLIEALPYELIEAAKIDGANNLRIVVSVVLPVA
                     RPAMMVLGMLTFVQAWNDFFWPYLALNQQNPTLQVALGQLSASYTPDQSIVMAGALIST
                     LPLLVVFVVFGKKIVGGIMSGAVKG"
     gene            3492..4949
                     /locus_tag="SGR_RS23585"
                     /old_locus_tag="SGR_4738"
                     /db_xref="GeneID:6211999"
     CDS             3492..4949
                     /locus_tag="SGR_RS23585"
                     /old_locus_tag="SGR_4738"
                     /EC_number="3.2.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012380830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH1"
                     /protein_id="WP_012380830.1"
                     /db_xref="GeneID:6211999"
                     /translation="MTVVRPDTVPQQAPAATAPFPTGFLWGAATAAYQVEGAAAEMGRT
                     PSIWDTFSHTPGRTLGGDTGDVAADHFHRYRDDVALMKRLGLQAYRFSVSWSRVQPTGR
                     GPAVERGLDFYRSLVDELLLAGIKPVATLYHWDLPQELEDAGGWPERATAERFAEYAAI
                     MARALGDRVGMWTTLNEPWCSAFLGYGSGVHAPGRTEPAAALRAAHHLNLAHGRATEAL
                     RANLPAAAQTSVTLNLHQVRPLTGSEADADAARRIDAVGNRVFTGPMLKGAYPEDLLAD
                     TERIVNWGELVRDGDLAAIAAPIDVLGVNYYTPTIVSTPASGAGDTRNDGHGSSDHSPW
                     PGSEHVAFHLAEGRPVTAMNWSVKPEGLYDLLMDVSREHPELPLMVTENGAAFDDAPDA
                     DGRVHDPERIAYLRGHLEAVRRAAADGADVRGYFLWSLMDNFEWGYGYAKRFGAVYVDY
                     ETQLRTPKSSAHWYGEVIARHALPPEA"
     gene            5129..6166
                     /locus_tag="SGR_RS23590"
                     /old_locus_tag="SGR_4739"
                     /db_xref="GeneID:6212000"
     CDS             5129..6166
                     /locus_tag="SGR_RS23590"
                     /old_locus_tag="SGR_4739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015577271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="STP|LacI,STP|Peripla_BP_3"
                     /protein_id="WP_003968984.1"
                     /db_xref="GeneID:6212000"
                     /translation="MAASRVRNGGRPTLEEVAARAGVGRGTASRVINGSPRVSDATRQA
                     VEAAVAELGYVPNRAARALAGNRTDAIALVVPEPETRFFAEPYFSAIVRGVGAALADTE
                     MQLLLTLVGNDRERRRLAQYLTAHRVDGVLLVAVHADDPLPELLEQLGMPCVISGARHA
                     AETLPSVDSDNFEGARAAVEHLVSRGRRQVATITGRLEVYGAQRRLDGYRAAVSAAGLA
                     PDERLIAPADFTEEGGARAMRDLLARRPGLDAVFVASDVMAAGARQVLREADRRIPEDV
                     ALIGFDDSVVARHMHPALTSVRQPIEEMGRRMAQLLLDEIAGRAPGDERPSVVLPTELV
                     VRDSS"
ORIGIN
        1 atgcgcatca cccgcagcgt tgccggtcga cgcaggagaa ccgccctcgt ggccaccacg
       61 ggcctcacgg tcaccgccct cctcctcacc ggatgcggcg gctcgtccga ctcggacaag
      121 ggcgccgacg cggacggcaa catcaccctg accctcgccg acttcgggca gttcgggtac
      181 aaggaggccg ggctcttcga gaagtaccac gagctgaacc cgaagatcac ggtcaaggag
      241 gacaccaccg ccgaggagaa gaactactac cccaagctcc tccagcagct gaactccggc
      301 agcggcctcg ccgacgtcca gggcatcgag gtcggccgga tcaaggagat cgtcgacacc
      361 aaggcggact ccttcgccga cctctcccag acgatcggcg tggacgagtg ggtgtcgtgg
      421 aaggcgaagc aggccaccgc ccccagcggc gcggtcatcg gcgcgggcac cgacatcggc
      481 cccatgtccc tctgctacaa ccgtgagctg ttcgagaagg ccgggctgcc caccgaccgc
      541 gccgaggtcg cgaagctgac ggagggcggc tgggaggact tcctggcgct gggcgagcag
      601 tacaagaaga aggcccccga gggcacgtac ttcatggact ccgcgagcgc catgttcaac
      661 gccgtggtca gctccagccc cgagcagtac tacgacgcga gcggcaagcc ggtctacgag
      721 acgagcgcca gcgtcgagaa gggctggaag ctcgccgccg aggccgcgtc caagaagctg
      781 acgcagggcc tggcccagtt cgaggaccag tggcaggcgg ccctgcgcaa gagcaccgtc
      841 gccaccgtcg tctgccccgc ctggatggcc ggccagatct ccacctacgc cggtgacgcc
      901 aacaagggca agtgggacat caccagcgcc cccggcaaca cctccgccaa ctggggcggc
      961 tccttcctcg ccgtcccgaa gtccgggaag aacgtcgccg aggccaccaa gctcgtcagg
     1021 tggctgaccg cccccgagca gcaggccgcc gtcttcaagg cgatcggcgt cttcccgtcc
     1081 aaccagggcg cctacgagct gccggacgtg aagaacgcga ccctgccgta cttcaacaac
     1141 gcccccatcg gccagatcta cgccgatggc gcgaagtcca tccccgaggc ggtcctcggc
     1201 ccgaaggacg gcgtgatcaa ggactccatc tccacccaga tcaacaacat ggagcagcgc
     1261 ggcaccagcc ccgacgacgc ctgggacgcg gccgtgcgga cgatcgacaa ggccatcggc
     1321 tgacctgatc cccgaccggc cgcgagccgg tcccgcgccg gggtgggcgg gcgacaaccg
     1381 cccgccccgc cgcccgccca cccctccggc cgcccgcagc tccactcctc cagccgcccc
     1441 tccggccgcc ccggccgtcc gtcggcgcac ccagggaagg actccccgcc cgtggcaacc
     1501 tcgaccccca cccgggatgc gtacgcgacc ccgccccgtg aaccgaagaa ggaaccgccc
     1561 agcgaacggc ggcagttgtg gcgcagccgg ctgtggcggt tcgacgacaa ggcgtccccg
     1621 tacgcgtaca tcgccccgtt cttcctggtc ttcggggcct tcgggctcta ccccctcctc
     1681 tacaccggct ggatcgccct gcaccgggtg gagatgaccg gcctggactc gatggagtgg
     1741 gtgggctggg agaacttcga caagatcctg cacgaccccg agttctggac ctcggtcagc
     1801 aacacgttcc tgatcggcgt catctccacc gtgccgcagc tcctggtcgc cctcggcctg
     1861 gcccacctcc tcaactacaa gctgcgggcc agcacgttct ggcgcacggt catcctcacc
     1921 ccgtacgcga cctcggtcgc ctcggccgcc ctcgtcttcg ccctggtgtt ccgggccgac
     1981 ggcgggctgc tgaactggac gctcggcctg gtcggcttcg acccggtcaa ctgggccaac
     2041 gggcactgga cgtcgaagct ggcgatctcg atcatcgtca tctggcgctg gaccgggtac
     2101 aacgcgctga tctacctcgc cgccatgcag gccgtcccca acgacctcta cgaagcggcc
     2161 tccctggacg gggcctcccg ctggcagcag ttccgcaagg tcaccatccc ctcgctgcgg
     2221 ccgacgatcc tgttcaccat cgtcatctcc accatcggct ccatgcagct gttcggcgag
     2281 ccgctgctgc tggagggcgg cgcgctgggc gccaccggcg gcaacgagaa ccagtacgag
     2341 acgctcagca tctacctcta caactacggc tggaacctcg gacatctcgg tccggccgcc
     2401 gccgtcgcct gggcgatgct cgccctcctg ctgatcatcg ccgcggccaa ctggttcatc
     2461 ggccgattcg tccgcaagtc cgcggtctga ccgggagcgc atccatgacc ctgaccagcc
     2521 ccacgcaccc cgcccccgtg aagctcgcgc cggccccgca gggcggcgcc ccgcggcggc
     2581 ccagccgctt ccggatgggc gccggccagc agctgaaggg cggcccgttc gcgtacattg
     2641 cgctcgccgt cgtcggcttc ggctcgctgc tgccgctcta ctggaccctg gtcgcggcct
     2701 cccgcaccca ggacgaggtc ctcgccgcca ccccgccgtt cctccccggc gggaaactgc
     2761 tggagaacct ccagaccgcc tgggagcagg ccaacctcgg cacggcgatc ctcaacagcg
     2821 tcatcgtctc gtcctcgatc accctcgcga cgctcttctt ctgcacgctc gccggctacg
     2881 cgttcgccaa gatgcgcttc cggggccgcg gctggctgat gaccgcggtc atcgccaccc
     2941 tcaccatccc accgcagctc agcgtcgtcc cgctgttcat gatgatgtcc ggcctcggct
     3001 ggggcgggca gctcgaatcc gtgatcttcc cgacgctggt gagcgcgttc ggcgtcttct
     3061 tcatgcgcca gtacctgatc gaggcgctgc cgtacgagct gatcgaggcg gccaagatcg
     3121 acggcgcgaa caacctccgc atcgtggtga gcgtggtgct gccggtggcc cgccccgcga
     3181 tgatggtgct cgggatgctc accttcgtcc aggcgtggaa cgacttcttc tggccctacc
     3241 tcgccctcaa ccagcagaac ccgacccttc aggtggccct cggccagctc agcgcctcgt
     3301 acacccccga ccagtccatc gtgatggcgg gcgcgctgat cagcacgctg ccgctgctgg
     3361 tggtgttcgt ggtcttcggc aagaagatcg tcggcgggat catgtccggc gcggtgaagg
     3421 gctgaccctc cctcgcccgg cgtcctctcc acctccttcc cacccctcac ttccccaggg
     3481 agcgctccca catgacagtc gtccgacctg acacggtccc gcagcaggcc cccgccgcca
     3541 cggccccctt cccgaccggt ttcctctggg gcgcggccac cgccgcctac caggtggagg
     3601 gcgcggcggc cgagatgggc cgcacgccct ccatctggga caccttcagc cacacgcccg
     3661 gccggaccct cggcggggac accggggacg tggcggccga ccacttccac cgctaccgcg
     3721 acgacgtcgc cctgatgaag cggctcggac tccaggcgta ccgcttctcg gtctcctggt
     3781 cccgcgtcca gcccaccggc cggggacccg ccgtggaacg cggcctcgac ttctaccgct
     3841 cgctcgtcga cgagctgctc ctcgccggca tcaagcccgt cgccacgctc taccactggg
     3901 acctgcccca ggagttggag gacgcgggcg gctggcccga gcgggcgacg gccgagcggt
     3961 tcgcggagta cgcggccatc atggcccgcg ccctgggcga ccgcgtgggg atgtggacca
     4021 cgctgaacga accctggtgc tcggccttcc tcggttacgg ctccggggtc cacgcccccg
     4081 gccgcaccga accggccgcc gcgctgcggg ccgcccacca cctcaacctc gcccacggcc
     4141 gggcgaccga ggcgctgcgc gcgaacctcc ccgctgccgc gcagacctcg gtcaccctca
     4201 acctccacca ggtgcgcccg ctgaccggca gcgaggcgga cgcggacgcg gcccgccgga
     4261 tcgacgcggt gggcaaccgc gtcttcaccg gtccgatgct gaagggcgcg tacccggagg
     4321 acctgctggc cgacaccgaa cgcatcgtca actggggaga gctggtccgc gacggcgacc
     4381 tcgccgcgat cgccgccccg atcgacgtgc tcggcgtcaa ctactacacg cccaccatcg
     4441 tcagcacgcc cgcctccggc gcgggggaca cccgcaacga cggccacggc agcagcgacc
     4501 actccccgtg gcccggctcg gagcacgtcg ccttccacct cgccgagggc cggccggtca
     4561 ccgcgatgaa ctggtcggtc aagccggagg ggctgtacga cctcctcatg gacgtctcgc
     4621 gcgagcaccc ggagctgccg ctgatggtca ccgagaacgg cgccgccttc gacgacgccc
     4681 cggacgcgga cggccgggtc cacgacccgg agcggatcgc ctatctgcgc ggccacctgg
     4741 aggcggtgcg ccgggcggcg gccgacggcg ccgacgtacg gggctacttc ctctggtcgc
     4801 tgatggacaa cttcgagtgg ggctacggct atgcgaagcg cttcggcgcg gtctacgtcg
     4861 actacgagac ccagctccgt acgccgaagt ccagcgccca ctggtacggc gaggtcatcg
     4921 cccgccacgc gctgcccccg gaggcctgac ccggcggcag cccgttgaga gcggtgggcc
     4981 cggtcgaccc cgaccgggcc caccgccttt ccgtcccctt cttgggagcg ctcccaatac
     5041 actgtccgta cgctcgtcgg ggtgatcggt ccaggacttg gattgactgt acggctgtga
     5101 gaaattgacc gggaacgggg aggcggccat ggcggcatcg cgagtacgga acggcgggcg
     5161 gcccacgctc gaagaggtcg cggcacgggc cggggtcggc cggggcaccg cctcacgggt
     5221 catcaacggc tcgccccggg tcagcgacgc cacccggcag gccgtcgagg cggccgtcgc
     5281 cgaactgggg tacgtcccca accgcgccgc ccgcgccctg gcgggcaacc gcaccgacgc
     5341 catcgcgctg gtggtccccg agccggagac ccgcttcttc gccgagccct acttctccgc
     5401 catagtgcgc ggtgtcgggg cggccctggc cgacaccgag atgcagctgc tcctcaccct
     5461 cgtcggcaac gaccgcgagc gccgcaggct cgcccagtac ctcaccgccc accgcgtcga
     5521 cggggtcctc ctggtcgccg tgcacgccga tgacccgctg ccggagctcc tggagcagct
     5581 gggcatgccc tgcgtgatca gcggcgcccg gcacgcggcc gagacgctgc cctcggtcga
     5641 ctccgacaac ttcgagggcg cgcgggccgc cgtggagcac ctggtctccc ggggccgccg
     5701 ccaggtggcc accatcaccg gccgcctgga ggtctacggc gcccagcgcc gcctggacgg
     5761 ctaccgcgcc gcggtctccg ccgccggcct ggcccccgac gagcgcctga tcgccccggc
     5821 cgacttcacc gaggagggcg gcgcccgggc catgcgcgac ctcctggccc gccgccccgg
     5881 cctcgacgcc gtcttcgtgg cctccgacgt gatggccgcg ggcgcccgcc aggtcctgcg
     5941 cgaggcggac cgccgcatcc ccgaggacgt ggccctgatc ggcttcgacg actcggtggt
     6001 cgcccgccac atgcacccgg ccctcaccag cgtccgccag cccatcgagg agatgggccg
     6061 ccggatggcc cagctcctcc tggacgagat cgcgggccgg gccccgggcg acgagcgccc
     6121 ctcggtggtc ctgcccacgg agctggtggt ccgcgactcg tcgtga
//
