LOCUS       CP012801               12585 bp    DNA     linear   BCT 16-OCT-2015
DEFINITION  Bacteroides cellulosilyticus strain WH2, complete genome.
ACCESSION   CP012801
VERSION     CP012801.1
DBLINK      BioProject: PRJNA289334
            BioSample: SAMN03852682
KEYWORDS    .
SOURCE      Bacteroides cellulosilyticus
  ORGANISM  Bacteroides cellulosilyticus
            Bacteria; Bacteroidetes; Bacteroidia; Bacteroidales; Bacteroidaceae;
            Bacteroides.
REFERENCE   1  (bases 1 to 12585)
  AUTHORS   Wu,M., McNulty,N.P., Rodionov,D.A., Khoroshkin,M.S., Griffin,N.W.,
            Cheng,J., Latreille,P., Kerstetter,R.A., Terrapon,N., Henrissat,B.,
            Osterman,A.L. and Gordon,J.I.
  TITLE     Genetic determinants of in vivo fitness and diet responsiveness in
            multiple human gut Bacteroides
  JOURNAL   Science 350 (6256), AAC5992 (2015)
   PUBMED   26430127
REFERENCE   2  (bases 1 to 12585)
  AUTHORS   McNulty,N.P.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-SEP-2015) Center for Genome Sciences and Systems
            Biology, Washington University School of Medicine, 4444 Forest Park
            Ave., Saint Louis, MO 63108, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method       :: HGAP 2.0 and Celera v. AUG-2014
            Assembly Name         :: B_cell_WH2_2.0
            Long Assembly Name    :: Bacteroides cellulosilyticus WH2 2.0
            Genome Coverage       :: 209x
            Sequencing Technology :: PacBio; Illumina MiSeq
            ##Genome-Assembly-Data-END##
FEATURES             Location/Qualifiers
     source          1..12585
                     /organism="Bacteroides cellulosilyticus"
                     /mol_type="genomic DNA"
                     /strain="WH2"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:246787"
     gene            1..3000
                     /locus_tag="BcellWH2_05309"
     CDS             1..3000
                     /locus_tag="BcellWH2_05309"
                     /inference="ab initio prediction:Prodigal:2.6"
                     /inference="protein motif:Pfam:PF00593.18"
                     /codon_start=1
                     /transl_table=11
                     /product="gnl|TC-DB|Q45780|1.B.14.6.1"
                     /protein_id="ALJ62511.1"
                     /translation="MQKYKMPIRLRIMACLIGMLLPMCMFAQQITVQGVVKDQTGETVI
                     GASVVQKNTTNGTITGIDGDFSLNVPSDAVIVVSFVGYKSLEVPVKGQKQIMVTLSEDS
                     EMLDEVVVIGYGTMKKSDLTGAVSSLGSKDIKDAPVSNLGQAIQGRISGVQVVDAGKPG
                     DNVSIKIRGLGSINNCDPLVVIDGVPTDLGLSSLNMADVERLDVLKDASATAIYGSRGA
                     NGVVMITTKRGTEGKGKLSVSANCAFQNATNVPSLLNASQYADLSNDMMVNSGRNPNPN
                     WANPSELGAGTDWMDELLRTGVMQNYTVSYSGGNEKSHYYVSGGFLDQSGTVRSVNYRR
                     FTFQSNSDAQVLKWLKFSNNITFSTDTKDSGSYNIGDALKALPVLPVKNEDGSWSGPEG
                     NSEWYGSIRNPIGPTQLNKSQTKGYNFLANLTAELTFTKWLKFKSTFGYDAKFWFIDNF
                     TPKYNWKPIPTEETSRYKSDNKSFTYLWDNYFLFDHTFAEKHRVGVMAGSSAQWNENDY
                     LNAQKNVFMFDNVHEMDNGQEMYAIGGSSNEWALLSYMARINYSYEDRYMLTATVRRDG
                     SSRFGKKNRWGTFPSVSAAWRISQESWFPKNDVVNDLKIRVGYGVTGSQASVGNYSYLA
                     SYNTSVYPFGTTSGNQTALVSSTLANPYIHWEEVAQTNIGFDASLFNSRIVFSLDAYLK
                     ETRDMLVKASIPITSGFEDTTTTYTNAGKVRNQGLEMSLHTINLTGELGWETNVTATYN
                     KNKIKDLNSAVPYYINQINNSYVTMLAKDYPINAFYGYVTDGLFQNQAEVDAHAVQPGA
                     EPGDIRFRDLNNDGVINDSDRTVIGNPNPSWFFSMNNNLSYKGFELSVFLQGVAGNKIY
                     NANNIDNVGMAAAYNQTTDVLNRWRGEGTSYSMPRAVFGDPNQNCRVSDRFVEDGSYLR
                     VKNITLSYTFPKQWLQKLQIENARLSLSCENVATITGYSGFDPEVDINGIDLSRYPISR
                     TFSVGLNFNF"
     gene            3012..4502
                     /locus_tag="BcellWH2_05310"
     CDS             3012..4502
                     /locus_tag="BcellWH2_05310"
                     /inference="ab initio prediction:Prodigal:2.6"
                     /inference="protein motif:Pfam:PF07980.5"
                     /codon_start=1
                     /transl_table=11
                     /product="gnl|TC-DB|E4RVP8|8.A.46.1.5"
                     /protein_id="ALJ62512.1"
                     /translation="MKKITNLLYVLAVLMLVSCNDFLDKSPKYAVDPETTVTDDVAVAL
                     TNACYKALQSSNLYNQRMWSLDIVAGNSLVGAGGGTDGLETIQASNFITQSDNGMALYM
                     WRSPWVGIGQCNIVLTSLPQAEAVSESIKNRCMGEAYFLRAHYYYILARLYGGVPLRLE
                     PYNPGESTAIARTTLDQTYEQIISDCKNAVDLLPAKAEYNEEEKGRACKDAALAMLADI
                     YLTLAPNHTSYYEDVVELCNEITNLGYDLSTCKYENNFDATINNGPESLFEVQYSGSTE
                     YDFWGTDGQSSWLSTFMGPRNSDFVAGSYGWNQPTEEFVSQYEEGDKRKELTVLYAGCP
                     DFDGKTYKSSYSNTGYNVRKFLVSKTISPEYNTNPNNFVVYRYADVLLKKAEALNEMGQ
                     PGQAAAPLNIVRKRAGLPEVSGLSQEAMREKIIHERRMELAFEGHRWFDMIRVNNGEYA
                     IRFLQSIGKNSVNKNRLLFPIPQTEMDANILMTQNPGY"
     gene            4525..6021
                     /locus_tag="BcellWH2_05311"
     CDS             4525..6021
                     /locus_tag="BcellWH2_05311"
                     /inference="ab initio prediction:Prodigal:2.6"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ALJ62513.1"
                     /translation="MKRYISHLVFALLGCMALPACVDNDYMELDKGHNELVLSTSNTEV
                     ALNEQAHGDDALELSWTTGTNYGTGNKISYTLELAKAGSNFAAPYVALENVVQEYTWKK
                     NVEELNNILREYFGVEATENVSLEARLTAKVTDREETQVATTSFSVTAYKPLTSTLYLV
                     GDATPGGWSADDATEMTRKDNGIFTWTGKMTAGSFKFITTLGAFLPSYNKGTDGKLVLR
                     TSADQPDESFTIEEEFNYIVEANLFTGVITLTQTENLRPAYDQLYFVGGMNDWGFVPMK
                     KDVLDPFLFRYARLFDAGQGGEFKFGTSEGSWESMYKAKNANAAYTDTEMVFVKGFDPD
                     NKWVLKDAECGKAYKICVDIRAGKERMMMSEFVPYEMIYMVGDAAPAGWSIGDATPMQA
                     TDNPYVFTWQGVLNVGELKLTCDKKEDWNGAWFMPTVADKQPSGETEPMLFLDKASDAF
                     KAQYLDVMIGGIDLKWKITTAGSYKITLNQLEETISIVKQ"
     gene            6099..7889
                     /locus_tag="BcellWH2_05312"
     CDS             6099..7889
                     /locus_tag="BcellWH2_05312"
                     /EC_number="2.4.1.248"
                     /inference="ab initio prediction:Prodigal:2.6"
                     /inference="similar to AA sequence:UniProtKB:P94286"
                     /codon_start=1
                     /transl_table=11
                     /product="GH66"
                     /protein_id="ALJ62514.1"
                     /translation="MKYIVYAMAAMFFLASCSKDNDETGGGNGGGGETGGVTDVTPVTS
                     DLTVNLTTDKACYKPGETVSFTADALPEGAKVRYRTLNKVISEQTVAGSSWTWTAPATD
                     FTGYLADVYRTKEDGTEVILGTIAVDVSSDWTRFPRYGFVATFDASKTESKIQEEMAFL
                     NRCHINGVQFQDWHNKHHWPLGGTREHLDAVYKDIANRDIYTQSVKDYIRIQHSFGMKA
                     MFYNLCFGALDDAAGDGVREEWYIFKGTGHTDKDAHTLPDSWKSNIYLLDPGNAEWQAY
                     IAQRNDDVYANLDFDGYQIDQLGNRGDRYDYKGNKVNLPKTYVSFIEAMKGKHPDKRLV
                     MNAVSSYGASQIAGTGKVDFLYNEVWGDEADFTDLYTILKANHQYGNQALKTVFAAYMN
                     YEKGSGEFNMPGILLTDAVMFALGGSHLELGGDHMLCSEYFPNTRLQMSDALKTAVVRY
                     YDFMTAYQNLLRDGGEEEKVTLVCTDASKNLNLNTWPPQKSAITSFARRVNGKQVVHLL
                     NFLSANSLSWRDLNGTMPEPRLVTKVPLKLNVAGKVSKVWVATPDAHAGASQELAFEQK
                     DGAITFTLPSLKYWSMIVME"
     gene            7910..10408
                     /gene="yicI_10"
                     /locus_tag="BcellWH2_05313"
     CDS             7910..10408
                     /gene="yicI_10"
                     /locus_tag="BcellWH2_05313"
                     /EC_number="3.2.1.177"
                     /inference="ab initio prediction:Prodigal:2.6"
                     /inference="similar to AA sequence:UniProtKB:P31434"
                     /codon_start=1
                     /transl_table=11
                     /product="GH31"
                     /protein_id="ALJ62515.1"
                     /translation="MRKYIYLFLILCCLSPHLYGGNVTGNCTSYSQEGRDVTFHLDDNS
                     AVQLQLCSPSVVRVWFSPDGKLQRGNPSFAVINEELEDVGTVQVDEQNACYEIFTPKLR
                     IRVNKAPFSLQIFDKYQKLLFSDYADKGHISDGERKVEYKTLRRDEHFFGLGEKTGKLD
                     RRGESYKMWNSDKPCYSVVEDPLYKSIPFFMSSYRYGIFLDNTYKTEFKFGTESRDYYS
                     FEAPGGEMIYYFIFGKDYKEIMKQYVALTGQPIMPPKWALGFAQCRGLLTTEKLSYEIA
                     EGYRKRGIPCDIIYQDIGWTQYLQDFNWRKENYQNPKKMLADLKGMGFKVIVSQDPVIS
                     QANEKQWEEADRLGYLVKDSTTGKSYDMPWPWGGNCGVVDFTIPEVADWWGAYQQKPID
                     DGIAGFWTDMGEPAWSNEEQTERLVMKHHLGMHDEIHNVYGLTWDKVVKEQFEKRNPDL
                     RVFQMTRAAYAGLQRYTFGWTGDCGNGDDVLQGWGQMANQIPVLLSAGLGVIPFVACDI
                     SGYCGDIEDYPAMAELYTRWVQLGAFNPLSRIHHEGDVAVEPWLFGEEAEKNVKAAIEM
                     KYRLLPYIYTYAREAYETGLPIMRPMFMEYPADLETVSTDAQFMFGSELLVAPVVKKGA
                     TNKNVYLPEGIWIDYNDKRTEYNGEQWTTANAPLNTIPMFVRKGSIIPQMPVMNYTDEK
                     AVYPITFEVFPATAGGETSFSLYEDVGTDLGYQRGEFMRTPVSCRTTEKGYVLEIGERA
                     GEKYALPGERNLMFCIYTGQMPKEALIDGQKVRKMKAEKLNEGMETEFKVTAWCPDKKQ
                     NLCMLRLPDDGVKHTIEFIY"
     gene            10432..12585
                     /locus_tag="BcellWH2_05314"
     CDS             10432..12585
                     /locus_tag="BcellWH2_05314"
                     /EC_number="3.2.1.22"
                     /inference="ab initio prediction:Prodigal:2.6"
                     /inference="similar to AA sequence:UniProtKB:Q8A6L0"
                     /codon_start=1
                     /transl_table=11
                     /product="GH97"
                     /protein_id="ALJ62516.1"
                     /translation="MRKLMLSAICLLFALAGKAEGVSSPSGQVKLDFELSKNGAPTYQV
                     EYKGKSVIKPSTLGLELKNANNLLDGFEVLKAFTSTFGETWQPVWGETKDIRNHYNELL
                     VKLKQPATDRYMNLRFRVYDDGVGFRYEFPQQKNLVYFVIKDEHTQFAMTGDHIAWWIP
                     GDYDTQEYDYTESKLSEIRGLMQGAITDNASQNQFSPTGVQTSLQMKTADGIYLNLHEA
                     ALVDYSCMHLNLDDKNLIFESWLTPDAQGDKGYMQSPCHTPWRTVIVSDDAREMLASNL
                     ILNLNDPCKYEDTSWIKPVKYVGVWWEMIAAGKPWAYTFDLPSVKLDETDYTKVKPNGI
                     HPANTENVKKYIDFAAEHGFDQVLVEGWNTGWEDWFGNSKDYVFDFLTPYPDFDIKYLN
                     EYAHSKGVKLMMHHETSASARNYERHMEAAYDLMNQYGYNSVKSGYVGNIIPRGEYHYG
                     QWMNNHYLYAVTEAAKHKIMVNAHEAVRPTGLCRTYPNLIGNESARGTEYEAFGGSKPF
                     HTTILPFTRLQGGPMDYTPGVFEMDMNKLNPNSHAHVNSTLARQLALYVTMYSPLQMAA
                     DLPENYERFMDAFQFIKDVALDWDDSRYLEAEPGRYITAARKAKGTNDWFIGCTSSEQG
                     HASTLKLDFLDADKQYIATVYADAKDADYKTNPQAYVIRKGIVSPKTVLKLKAAPGGGY
                     AISIMEVKDKAELKGLKKLSGNI"
ORIGIN
        1 atgcaaaagt acaaaatgcc gatcaggctt cgaattatgg cttgtctgat aggaatgtta
       61 cttccgatgt gcatgttcgc acagcaaatc acagtacaag gtgtagtgaa agaccagacc
      121 ggagaaaccg ttatcggtgc cagtgtggtg cagaagaaca caacgaacgg tacgataacg
      181 ggtatcgatg gcgatttctc gctgaatgtg ccttcggatg ccgttatagt agtttcattc
      241 gtgggctata agtctttgga agttcccgtg aaaggacaga aacagattat ggtaacactc
      301 tcggaagaca gtgaaatgct ggacgaagtg gtggttatcg gttatggaac catgaagaaa
      361 agtgacctta ccggtgctgt ttcctctttg ggaagcaagg acatcaaaga tgctcccgtt
      421 tctaacttgg gacaagccat tcagggccgc atctccggtg tgcaggtagt ggatgccgga
      481 aagcccggtg acaatgtatc tatcaagatt cgtggtctgg gctccattaa caactgcgat
      541 ccgctggtgg tgattgacgg tgtgcctacc gacctgggac tgtcttcact gaacatggcg
      601 gatgtggaac gcctggacgt attgaaagac gcatcggcta cagccattta cggttcgcgt
      661 ggagccaatg gggtagtgat gatcaccacc aagcgcggaa cggaagggaa aggaaaattg
      721 tcggtatcgg ctaattgtgc tttccagaat gccacgaacg ttccttcttt actgaacgca
      781 agccagtatg ccgatttgag taatgatatg atggtgaaca gcggtcgcaa cccgaatccg
      841 aattgggcaa atccttcgga actgggtgca ggtaccgact ggatggacga attgctgcgc
      901 acgggtgtga tgcagaacta tacggtaagt tattccggag gaaatgagaa gtctcattat
      961 tatgtgtccg gtggttttct tgatcagtcg ggtacggtgc gcagtgtaaa ctatcgccgt
     1021 tttacgtttc agtccaacag cgacgcacag gtgctgaagt ggttgaagtt ctccaataat
     1081 atcactttca gtactgatac gaaggattcg ggcagctata atatcggtga tgcgctgaag
     1141 gctcttcccg ttcttccggt gaagaatgaa gacggctcat ggagtgggcc ggaaggtaat
     1201 tcggaatggt acggtagcat ccgcaacccg atagggccta cgcaactgaa caaaagtcag
     1261 acgaaaggtt ataacttcct tgccaacctg acagcggaac tgacttttac caaatggctg
     1321 aaattcaaga gcactttcgg ttacgatgcc aaattctggt tcatcgataa cttcacgccg
     1381 aaatataact ggaagcctat tccaacggaa gaaacttcac gttacaagag cgataataaa
     1441 tcattcactt atctgtggga taactatttc ctgttcgacc atacctttgc agaaaagcat
     1501 cgtgtgggag tgatggcagg ttcatctgca cagtggaatg agaatgatta cctgaatgca
     1561 cagaagaacg tcttcatgtt cgacaatgtg catgaaatgg ataacggtca ggagatgtac
     1621 gccattggcg gcagttccaa tgaatgggca ttgctctctt acatggcacg tatcaactac
     1681 tcttacgaag accgctatat gctgacggca actgtccgcc gtgatggttc cagccgtttc
     1741 ggtaaaaaga accgttgggg tactttccct tctgtatctg ccgcatggcg catttcgcag
     1801 gaaagctggt tcccgaagaa tgacgttgtg aacgacctga aaatacgtgt aggatatgga
     1861 gtgacgggta gccaggcaag tgtcggcaat tatagttacc tggcatctta caacaccagt
     1921 gtatatccat tcggaacaac gagcggcaat cagaccgcat tggtttcctc tacgcttgcc
     1981 aatccttaca tccattggga agaggtggca cagacgaata tcggttttga tgcttccctg
     2041 ttcaattcac ggatcgtatt ctcactggat gcttatctga aagagacaag ggatatgttg
     2101 gtgaaggcat ccatccccat cacatcggga tttgaagata ccaccaccac ttatacgaat
     2161 gccggtaaag tgcgcaacca gggcttggaa atgagtctgc acaccatcaa tctgaccgga
     2221 gaactgggtt gggaaacaaa tgtgaccgcc acgtacaata aaaataagat taaggacctg
     2281 aacagcgcgg ttccttacta tatcaaccag atcaataact cgtatgtcac gatgctggca
     2341 aaagactatc cgattaatgc cttctacggc tacgtgacgg atggcttgtt ccaaaaccag
     2401 gcggaagtgg atgcgcatgc cgtgcagccg ggagctgaac cgggtgatat ccgtttcagg
     2461 gatttgaaca acgacggtgt catcaacgac agtgaccgca ctgtgattgg caatcccaat
     2521 cccagttggt tcttctcaat gaacaacaac ttgtcttata aaggattcga gctttccgta
     2581 ttccttcagg gagtggccgg caataagatt tataatgcca acaatatcga caatgtcggt
     2641 atggctgccg catacaacca gacgactgat gtgctgaacc gttggcgcgg agaggggaca
     2701 agctactcca tgccgcgtgc cgtgttcggc gatcctaacc agaactgccg tgtatccgac
     2761 cgctttgtag aagacggatc ttacttgcgt gtgaagaata tcactctctc ttataccttc
     2821 ccgaaacaat ggttgcaaaa gttgcagata gagaatgcac gcctttccct ttcttgtgag
     2881 aatgtggcta ccattaccgg gtattccggt ttcgatccgg aggtggatat caacggtatt
     2941 gatttgtccc gttaccccat ttcccgtaca ttcagtgtag gattaaactt taacttttaa
     3001 ttgatttgga tatgaaaaag ataacaaact tactatacgt gctggctgta ttgatgctgg
     3061 tatcatgtaa tgacttcctg gataagtcgc ccaaatatgc cgttgatcct gaaacaaccg
     3121 tgaccgatga tgtggccgtg gcactgacaa atgcttgcta caaggcgctt cagtcttcca
     3181 atctctacaa ccagcgtatg tggtcgctgg atatcgttgc gggcaacagc ctggtaggtg
     3241 caggcggtgg tacggacggt ctggaaacca tacaggcatc caattttatc acgcagagcg
     3301 ataatggtat ggccctgtat atgtggcgtt ctccgtgggt aggcatcggg cagtgtaaca
     3361 ttgtgctgac cagtcttccg caggccgaag ccgtatcgga aagcataaag aaccgttgta
     3421 tgggtgaagc atatttcctt cgtgcccatt actattatat cttagcccgt ttgtatggcg
     3481 gcgttccttt gcgtctggaa ccttataatc cgggtgaatc tactgcaata gcacgcacta
     3541 cgttggatca gacttatgag cagatcattt cggactgtaa gaatgcggtc gatttgcttc
     3601 cggcgaaagc ggaatataat gaagaagaaa aaggacgtgc ctgtaaggat gctgcccttg
     3661 ctatgctggc ggatatctac ctgacactgg ctcccaacca tacgagttat tatgaagacg
     3721 tggtggaact gtgcaatgag attacgaacc tgggttacga cctttctacc tgtaagtatg
     3781 aaaataactt cgatgctacc atcaataacg gtcccgaatc tctgtttgaa gtgcagtatt
     3841 ccggaagtac ggaatatgat ttttggggaa cggacggtca atcttcctgg ctttccactt
     3901 ttatggggcc ccgtaactcg gactttgttg caggcagcta cggctggaat cagcctacgg
     3961 aggaatttgt gagccagtat gaagaaggtg acaaacggaa agaactgacg gtgctttatg
     4021 caggttgtcc ggacttcgac gggaagactt acaagagttc ttattccaat accggatata
     4081 acgtgcgcaa atttctggtg tccaagacta tttcgccgga atacaatacg aaccccaata
     4141 actttgttgt gtaccgctat gcggatgtct tgctgaagaa agcggaagcg ctgaatgaaa
     4201 tgggacaacc cggccaagct gccgctcccc tgaatatagt tcgcaaacgt gccggactgc
     4261 cggaagtttc gggcctgtca caggaggcga tgcgtgagaa gattattcac gaacgacgca
     4321 tggaactggc tttcgaagga catcgctggt tcgatatgat ccgcgtcaat aatggagagt
     4381 atgccatccg tttcctgcaa tccatcggca agaacagtgt gaacaagaat cgtctgttgt
     4441 tccccattcc gcagacggaa atggatgcga atatactgat gacacagaat ccgggttatt
     4501 aatcacttaa atcagaagaa gaatatgaaa agatatattt cacatttagt atttgcattg
     4561 ctgggttgca tggcactgcc tgcatgcgtg gacaatgact atatggaact ggacaagggg
     4621 cacaatgaac tggtgctttc caccagcaac acggaagtcg ctttgaacga acaggcgcat
     4681 ggcgatgatg ccttggaact ctcctggaca acgggcacga attatggtac gggaaataag
     4741 atttcctata cactggaact tgccaaagcg ggcagtaatt ttgccgctcc ttatgtggct
     4801 ttggagaacg tcgtgcagga atatacctgg aagaagaacg tggaggaatt gaataacatc
     4861 cttcgtgagt attttggtgt ggaagctact gaaaacgtct ctctggaagc acgcctgaca
     4921 gccaaagtaa cggatcggga agagacacag gtggccacca cctcttttag tgtcactgcc
     4981 tacaaaccgt tgacttctac tctttacctg gtaggtgatg ccactcccgg cggttggagt
     5041 gcggacgatg caacggaaat gacccggaaa gataatggta tctttacatg gacgggaaaa
     5101 atgactgcgg gttccttcaa gtttatcact acgctggggg ctttcttgcc gtcgtacaac
     5161 aaaggaactg acggaaagct ggtgcttcgt accagtgccg atcagccgga cgaatcgttt
     5221 acgattgaag aagagttcaa ctatattgtt gaagcgaacc tgtttaccgg tgttatcacc
     5281 ttgactcaga ccgagaacct cagaccggct tacgatcagc tttatttcgt tggaggtatg
     5341 aacgactggg gatttgtgcc gatgaaaaag gatgtgctcg atccgttcct gttccgctat
     5401 gcccgtttgt ttgatgcagg ccagggcggg gaattcaagt tcggaacttc ggaaggaagc
     5461 tgggagagca tgtataaggc aaagaatgcc aatgccgctt acaccgatac ggaaatggta
     5521 tttgtgaaag ggttcgatcc tgacaataaa tgggtgctga aagatgccga atgtggtaag
     5581 gcctataaga tatgtgtcga tatccgtgca gggaaagagc gcatgatgat gagcgaattt
     5641 gttccttatg agatgattta tatggtaggg gatgctgcgc ctgcgggatg gagcattgga
     5701 gatgctacgc cgatgcaggc cacggataat ccgtatgtat ttacctggca aggtgtactg
     5761 aatgtgggtg agttgaagct gacctgtgat aagaaagagg actggaacgg tgcctggttt
     5821 atgccgaccg tagctgataa gcagccttcg ggcgagacgg aaccaatgtt gttcctggat
     5881 aaggccagcg atgctttcaa agctcaatac ctggatgtaa tgattggagg tatcgacctg
     5941 aaatggaaga ttacgacggc tggttcttat aagattactc tgaatcaact ggaagagact
     6001 atttcgatag tgaaacaata aaataaatga taattgagat acttcgcgta tcatgccgct
     6061 aaattattac tcagaaataa cccttaaaat tcaataggat gaaatatata gtttatgcaa
     6121 tggctgccat gttctttttg gcttcgtgca gcaaagacaa tgatgaaacc ggcggtggta
     6181 acggcggtgg aggagaaacc ggaggagtga ctgatgtcac tcccgttacc tccgatttaa
     6241 ccgtgaacct gactactgac aaggcttgtt acaaaccggg tgaaaccgtt tccttcacag
     6301 ccgatgccct gcctgaggga gcaaaggtac gttaccgtac tttgaacaag gtaatctccg
     6361 aacagacagt cgcaggcagt tcctggacgt ggactgcccc tgcaacggat ttcaccggat
     6421 atctggcgga tgtctatcgc actaaagaag acggtacgga agtcattctc ggtactattg
     6481 ccgtcgatgt atccagcgac tggacacgct ttccgcgtta tggctttgtc gccaccttcg
     6541 acgcttctaa aacggaaagt aaaattcagg aggaaatggc ttttctgaac cgttgccata
     6601 tcaatggtgt gcagtttcag gattggcaca acaagcacca ctggccgtta ggcggtacgc
     6661 gcgaacatct cgatgcggta tataaggata ttgccaaccg ggatatctat acacagtcgg
     6721 taaaggatta tatccgcatc cagcactcgt ttggaatgaa ggcgatgttt tataatcttt
     6781 gtttcggtgc gctcgatgat gcagccggtg acggtgtgag ggaagaatgg tacatcttta
     6841 aaggcacagg gcatacggat aaggatgcgc atacgttgcc tgacagttgg aagagcaata
     6901 tctatttgct cgatccgggt aatgccgaat ggcaggcata tattgcccag cgcaacgatg
     6961 atgtctatgc caatcttgac tttgacggct atcagataga ccagttggga aatcgtggcg
     7021 accgctatga ttacaagggg aataaggtga atctgcctaa gacttatgtt tcgtttattg
     7081 aagctatgaa ggggaaacat cctgataaga gactggtgat gaatgcagta agtagctatg
     7141 gggcgtctca gattgcaggt acggggaaag tagatttcct gtataatgaa gtttgggggg
     7201 atgaagctga ttttacggat ttatatacga tcctgaaagc gaaccatcag tacggaaatc
     7261 aggctctgaa gacggtgttt gcggcttata tgaattatga aaagggttcc ggcgagttca
     7321 atatgccggg aatcttgctg acggatgcgg tgatgtttgc tctgggaggt tcgcacctgg
     7381 aattgggagg cgaccacatg ttgtgcagtg aatattttcc aaatacccgt ttgcagatga
     7441 gtgatgcctt gaagacggct gttgtgcgct attatgactt tatgactgct tatcagaatc
     7501 ttcttcgcga tggcggggag gaggagaagg taactttggt atgtacggat gcaagcaaga
     7561 atctgaatct gaacacttgg ccgccacaga aatcagccat tacttctttc gccagaaggg
     7621 tgaacggcaa acaggtggtt catctgctga acttccttag tgcaaacagt ttaagttgga
     7681 gagacctgaa cgggacaatg cccgaaccac ggttggtgac taaagtgccc ttgaagctga
     7741 atgttgcagg gaaagtgagc aaagtgtggg tagctactcc cgatgcacat gccggagctt
     7801 cgcaggaatt agcttttgaa cagaaagacg gagcgataac ctttacgctt ccttcactga
     7861 aatactggag catgattgta atggaataaa ttataaaaga tatagaacca tgagaaaata
     7921 tatatattta tttttaatac tgtgttgcct gtctccgcac ttatatggcg gaaatgtaac
     7981 gggaaactgt acttcttatt cgcaggaagg gagagacgtt acgtttcatt tagacgataa
     8041 ttcggctgtg cagttgcaac tttgcagtcc ctccgttgtg cgcgtctggt tttcgccgga
     8101 cggtaagttg cagcggggaa atccttcctt tgcagtgatt aatgaagaat tggaagatgt
     8161 aggcaccgtc caagtggacg aacagaatgc ctgttatgag atatttacgc ctaaactgcg
     8221 tatccgcgtc aacaaggctc cgttcagctt gcagatattc gacaagtatc agaagctttt
     8281 gttcagcgac tatgccgaca aggggcatat tagcgatgga gagcgtaaag tggagtataa
     8341 gaccctgcgc cgggatgagc atttcttcgg tttaggtgaa aagaccggca agctggaccg
     8401 ccgaggcgaa tcttataaga tgtggaacag tgataaacct tgttacagcg ttgtggaaga
     8461 tcccctgtac aagagtatcc ctttctttat gagcagttat cgctatggta tatttctgga
     8521 taacacgtat aagacagaat tcaaattcgg cactgagagc cgtgattatt acagctttga
     8581 agctcctggt ggggagatga tttactactt catcttcggt aaggattata aggaaatcat
     8641 gaaacagtat gtcgcattga ccggacaacc catcatgcct ccgaagtggg cactgggctt
     8701 tgcacaatgc cgcggcctgc tgactaccga gaagctctct tatgaaatag ccgaaggata
     8761 ccgcaagcgt ggtattcctt gcgatatcat ctatcaggat ataggctgga cacaatacct
     8821 acaggacttc aactggcgga aagaaaacta tcagaatccg aagaagatgc tcgccgactt
     8881 gaaagggatg ggcttcaaag tgattgtttc gcaagacccg gttatctctc aggctaatga
     8941 aaaacaatgg gaagaagcgg accgcttggg ttatctggtg aaagactcca ctacgggtaa
     9001 gagctatgat atgccttggc cgtggggtgg caactgcggt gtggtggact ttaccattcc
     9061 cgaagtggcg gactggtggg gagcttatca gcagaaaccg atagatgacg gcattgccgg
     9121 cttctggacg gatatgggtg aacctgcctg gagcaatgag gaacaaacgg aacgtcttgt
     9181 aatgaaacac cacctgggta tgcacgatga aattcataac gtgtatggtc tgacctggga
     9241 caaggtggta aaggaacagt ttgagaaacg gaatccggat cttcgtgtct tccagatgac
     9301 acgtgccgcc tatgcaggat tgcagcgtta caccttcggc tggaccggag attgcggcaa
     9361 tggagacgat gtgctgcaag gctggggaca gatggctaat cagatcccgg tacttttatc
     9421 tgccggactg ggtgtgattc ctttcgttgc atgtgacatt tccggttatt gcggggatat
     9481 tgaagattat cccgctatgg cggaacttta tacccgttgg gtacagttgg gagcgttcaa
     9541 tcctctgagc cgtattcacc atgaaggaga tgtggcggta gaaccgtggc tctttgggga
     9601 ggaagcggag aagaacgtta aagctgccat agaaatgaaa tatcgcttgc tgccttatat
     9661 ttatacttat gcccgcgaag cgtatgaaac gggtttgccg attatgcgcc ccatgtttat
     9721 ggaatatccg gcggatttgg aaacagtctc tacggatgca caattcatgt ttggtagcga
     9781 actgctggta gctccggtgg tgaagaaggg ggcaactaat aagaatgttt atctgcccga
     9841 aggtatctgg attgattata atgacaagcg cacggaatat aacggcgaac agtggactac
     9901 ggcaaatgct ccgctgaata ccattcctat gtttgtgcgg aaaggaagta tcatccctca
     9961 gatgcctgtg atgaattata cggatgagaa agcggtttat ccgattacat ttgaggtatt
    10021 tccggctacg gcgggcggcg aaacgtcttt ctccctgtat gaagatgtag gaactgatct
    10081 ggggtatcag cgtggggaat ttatgcgtac tcctgtatct tgccggacaa cggaaaaggg
    10141 atatgtgctc gaaatcgggg aaagggcggg agagaagtat gcccttccgg gagaacgcaa
    10201 cctgatgttt tgcatttata ccgggcagat gccgaaggaa gcgcttattg acggacagaa
    10261 agtaaggaag atgaaagcgg aaaaattgaa tgaaggaatg gaaacggagt tcaaggttac
    10321 tgcatggtgt ccggataaga aacagaatct ttgtatgttg agattgccgg atgacggggt
    10381 gaaacacacg attgaattta tttattaata gcaaccataa aaagtatagt tatgagaaag
    10441 ttaatgctta gcgcaatttg tcttcttttt gccttagcgg ggaaagcaga aggagtgtcg
    10501 tctccttcgg gccaagtgaa actggatttc gaattatcaa agaatggcgc tccaacctat
    10561 caggtggagt ataaagggaa atccgtgatt aagcccagta ccttgggact ggaattgaag
    10621 aatgccaata atctgctgga tggttttgaa gtcctgaaag cttttacctc taccttcggc
    10681 gaaacctggc aaccggtgtg gggagagacg aaagatattc gtaatcacta caacgaattg
    10741 ctggttaaat tgaaacagcc cgccacggat cgttatatga accttcgttt tcgtgtatat
    10801 gatgatggtg taggattccg ttatgagttt ccgcaacaga agaatctggt ttacttcgtg
    10861 attaaggacg aacataccca gtttgctatg acgggcgatc atatcgcctg gtggattccc
    10921 ggtgattacg atactcagga atatgattat acggaatcca aactttcgga aattcgcggt
    10981 ttgatgcagg gagccattac tgataatgcg tcacaaaacc agttttcgcc gacaggtgta
    11041 cagacttccc tccagatgaa aacggctgac ggaatctatc tgaatctcca tgaagctgct
    11101 ttggtggatt attcgtgcat gcatctgaat ctggatgata agaaccttat ctttgaatcc
    11161 tggctgacgc cggatgcaca gggcgataaa gggtatatgc agtcaccttg tcacactccg
    11221 tggcgtacgg tgatagtcag tgatgatgcc cgtgaaatgc tggcttccaa tctgatactg
    11281 aatctgaatg atccttgtaa gtatgaggac acatcctgga ttaagcctgt gaagtatgta
    11341 ggcgtgtggt gggaaatgat tgcggcaggc aagccgtggg catatacatt tgatctccct
    11401 tccgtaaaac tggatgaaac ggattatacg aaagtgaaac cgaatggtat tcaccccgcc
    11461 aatacggaga atgtaaagaa gtacattgat tttgctgcgg agcatggttt cgaccaggta
    11521 ttggtagaag gctggaatac cggttgggaa gactggttcg gcaacagcaa ggattatgtt
    11581 ttcgactttc tcactccata tcctgatttt gatatcaaat acctgaatga gtatgctcac
    11641 tccaaaggtg tcaaactgat gatgcatcat gagacatcgg cttccgcacg caactacgaa
    11701 cgccacatgg aggctgccta tgacttgatg aaccaatacg gttacaattc cgtgaaaagc
    11761 ggttatgtgg gtaatatcat tccgcgcggc gaatatcatt atgggcagtg gatgaacaat
    11821 cattacctgt atgccgtgac tgaagctgcc aagcataaga ttatggtgaa tgcccacgag
    11881 gctgtacgcc ccactggttt atgccgtacg tatccgaacc tgataggaaa tgaatctgcc
    11941 cgtggcacgg aatatgaagc tttcggaggc agcaagcctt tccacacgac cattcttcct
    12001 tttacccgtc tgcaaggcgg accgatggat tatacgccgg gtgtctttga aatggatatg
    12061 aataaattga atccgaatag tcacgctcat gtaaactcta cattggcgcg tcagttggca
    12121 ctctacgtca cgatgtacag ccctctgcaa atggcagctg atctgcctga gaactatgaa
    12181 cgctttatgg atgctttcca gttcattaag gatgtggctt tggactggga tgacagccga
    12241 tacctggaag cagaaccggg acgctatatt acggctgccc gcaaggcgaa aggtacgaat
    12301 gattggttta taggttgtac cagcagtgag cagggacatg cttctactct gaaactggat
    12361 tttctggatg ctgataaaca gtatatagct actgtttatg cggacgcaaa ggatgctgat
    12421 tataaaacga atccgcaagc ttacgtaatt cgtaaaggga ttgtttctcc taagaccgtg
    12481 ctgaaattga aagcggctcc gggtggtggt tatgccatca gcattatgga ggtgaaagat
    12541 aaggcggaat tgaaaggatt gaaaaagcta tccggtaata tctga
//
