LOCUS       CP012801               11484 bp    DNA     linear   BCT 16-OCT-2015
DEFINITION  Bacteroides cellulosilyticus strain WH2, complete genome.
ACCESSION   CP012801
VERSION     CP012801.1
DBLINK      BioProject: PRJNA289334
            BioSample: SAMN03852682
KEYWORDS    .
SOURCE      Bacteroides cellulosilyticus
  ORGANISM  Bacteroides cellulosilyticus
            Bacteria; Bacteroidetes; Bacteroidia; Bacteroidales; Bacteroidaceae;
            Bacteroides.
REFERENCE   1  (bases 1 to 11484)
  AUTHORS   Wu,M., McNulty,N.P., Rodionov,D.A., Khoroshkin,M.S., Griffin,N.W.,
            Cheng,J., Latreille,P., Kerstetter,R.A., Terrapon,N., Henrissat,B.,
            Osterman,A.L. and Gordon,J.I.
  TITLE     Genetic determinants of in vivo fitness and diet responsiveness in
            multiple human gut Bacteroides
  JOURNAL   Science 350 (6256), AAC5992 (2015)
   PUBMED   26430127
REFERENCE   2  (bases 1 to 11484)
  AUTHORS   McNulty,N.P.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-SEP-2015) Center for Genome Sciences and Systems
            Biology, Washington University School of Medicine, 4444 Forest Park
            Ave., Saint Louis, MO 63108, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method       :: HGAP 2.0 and Celera v. AUG-2014
            Assembly Name         :: B_cell_WH2_2.0
            Long Assembly Name    :: Bacteroides cellulosilyticus WH2 2.0
            Genome Coverage       :: 209x
            Sequencing Technology :: PacBio; Illumina MiSeq
            ##Genome-Assembly-Data-END##
FEATURES             Location/Qualifiers
     source          1..11484
                     /organism="Bacteroides cellulosilyticus"
                     /mol_type="genomic DNA"
                     /strain="WH2"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:246787"
     gene            1..3255
                     /gene="pfeA_7"
                     /locus_tag="BcellWH2_04351"
     CDS             1..3255
                     /gene="pfeA_7"
                     /locus_tag="BcellWH2_04351"
                     /inference="ab initio prediction:Prodigal:2.6"
                     /inference="similar to AA sequence:UniProtKB:Q05098"
                     /codon_start=1
                     /transl_table=11
                     /product="gnl|TC-DB|Q45780|1.B.14.6.1"
                     /protein_id="ALJ61568.1"
                     /translation="MKKLLSVLFLLSFTLASAVYAQDIQIKGTVVSGADNEPLPGVNVV
                     VKGNATTGTITGIDGEFTLSVPSGATLSISYIGFKSQDIPVNGRRELKIVLQEDSEALD
                     EVVVVGYGVQKKSVVTASIAKVSSEDIAGKAPVRMDNALKGLAAGVDVTSASGQPGDSP
                     RVRIRGIGTINNSDPLYIVDGMPIGGGLDFVNPNDIESIEVLKDAASGAIYGARAANGV
                     ILVTTKKGKMGKTQINYNFSYGWQSAWKQRDVTSATDYAVLQNESRVNGGQAPAYADPY
                     NLIDGNGQAIKGFGTDWQDLVFNDNAPVVNHDVTISGASEKINYYLSLGYYTQDGIVGG
                     NYGQSNYDRLTIRSNTQYNLIDASKERSFLNKLDLGVNIAYMRTHATGISTNSEFGSAL
                     GSALYLSPILTPTLTGDAATDMIDYYKTYDLPRDANGNPYTVPGYGGAYQEMNNPLAMM
                     TLSPQKNWSHKFVPKFSLDLQLWDNLKYHFSYSADMGFWGYDKATTSRFYLSGNNNASH
                     TSVEANKEQNVTWQLENTLTYDKTIGKHTFGVVLGQSALKYKGDYLKGNRWNLVNPDKP
                     SIDYATGNIEYTYKTDGNGDYILDKDGNKIISSTTVQYGTSGAPRVEHTMSSMFARFSY
                     NYDERYMIQATIRRDGSSRFGPNNKYGTFPSVSAGWNVTNEAFMENTRAWLTNLKIRAS
                     WGKNGNDNIAEFAYTSLTAMGNNVLLGKDAVKYIGSKAQRLANPDLKWEESEQTDFGID
                     MGFFNNALTFSADYYIKKTNGMIMEMPIPSYVGESKPLGNVGDMENSGFEFELGYKWNI
                     SDAKFAVKGNATYLKNTLKNLGNDTGYMDFDGIQGLSGGGTRGSNGQPFPYFFGYKTDG
                     VFQNMDEVRAYVNKDGEMIMPNAVPGDTRFVDVNGDGSISADDRTNIGNGTPDWTYGLN
                     FNADWKGFDFNIFFQGVAGADVFDATYRTDVSSGNYPSWMLGRWTGEGTSNKYPRLAVG
                     DATNWMVSDLYVCDGSYLRLKNITLGYTLPKALTRKLTIERLRFYVQAENLVTWTKYWG
                     FDPEISSGPDGIKSLGIDRGVYPQARTFTVGVNVSF"
     gene            3275..4846
                     /locus_tag="BcellWH2_04352"
     CDS             3275..4846
                     /locus_tag="BcellWH2_04352"
                     /inference="ab initio prediction:Prodigal:2.6"
                     /inference="protein motif:Pfam:PF07980.5"
                     /codon_start=1
                     /transl_table=11
                     /product="SusD family protein"
                     /protein_id="ALJ61569.1"
                     /translation="MKTNKILAIGLLSVATVLATGCSDSFLEVDNPTGEPLEDYYTTDA
                     HIQEALIAAYDPIHWADWGLDQYNALNIDAEIMGDNFWVGGSTKTDMQNWHMLFNYEGN
                     ENYTLSSLWTVDYSGVKRCNDLLKYLDWATDVTAENRKSYEMQARCLRVFYYNMLWHYF
                     GNVPFYLENLSKPPYTAPQYTADDVYNELIVELEAVIDSKVLPLKYYKTAKGENDDSQL
                     GRVTQAMAYMMYAEMVMYQNDEARFAKALGYMKEIIADSNFQLVTDYASIWETNGEWCN
                     ESIWEINYEQTNSERGWGSPLAVGGTVLPTLISPNTFTADSEWTGEGWGFLPMRLETYE
                     MFSSTDKRRDATCWDVRGTTYKDRYQDTHIWLQKYRPYDRNFKSAPFDQNLNYNNNYRY
                     YRYAETLLNAAELSLRTGGSATGEAKTWLNAVRTRAGLAELSTATVDDILTERRLEFVG
                     EGKRYFDLVRAENISGVSSKNKATTALVPDQYGYRTNSWTLKKKHIPIAQGELDSDPAL
                     IQNDYK"
     gene            4878..6347
                     /locus_tag="BcellWH2_04353"
     CDS             4878..6347
                     /locus_tag="BcellWH2_04353"
                     /inference="ab initio prediction:Prodigal:2.6"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ALJ61570.1"
                     /translation="MKNIFKYMAGVLIAGFAMTACSPEDFSGASQDGLPKLADYKAAVT
                     VDQETNRVTFNIVDAQGQNPKGVYPIWVINISPIVKTTVNGYQTGLVPLAGEYSYSLQV
                     GNKNGISDGTIEGTFTINTTRYDFSDVVSKLTNKATKEWRVYSAKAGHLGCGESPKDPA
                     GWWSAPAEDKVSEGIYDDRITFTAGEKLAEGAYKYSAGEDGLTFCNKGVTTLGVTAAEA
                     DYSTACVGVNGALSEATYNLGYNAELDCVTITLPAKTLFPYMADDAQMNGAMTYIITDL
                     NSKTMTLVIELSGISWQIILVNGDDEAVEEAFDPELVNWCAVDAPENLGAGFNTKGEMT
                     FWFAAADWQQIGDPEFSYADGVYTVTTKDATVEPWQGQCVIGEVPLTIEGEEFYDIACK
                     VVASVSVDRFTVKVNKDPDVEGDPNALFAKVDVVLKKGENILRFAKRTGINSDGDPVSF
                     EQGKFIVDLGGTPAGVKIEISDIIIQKHNPK"
     gene            6467..7825
                     /gene="bglA_2"
                     /locus_tag="BcellWH2_04354"
     CDS             6467..7825
                     /gene="bglA_2"
                     /locus_tag="BcellWH2_04354"
                     /EC_number="3.2.1.73"
                     /inference="ab initio prediction:Prodigal:2.6"
                     /inference="similar to AA sequence:UniProtKB:P45798"
                     /codon_start=1
                     /transl_table=11
                     /product="GH16"
                     /protein_id="ALJ61571.1"
                     /translation="MKKLNIILLFLLLFISCSNEDAGNLVTDDVTLECSPEKVETSGAG
                     GVYTLDVTCSDSEWTALASDDCSSWIAVKVAGSLSSKGTATVTVSANTSKDSRNGSVII
                     KSGAKRVVIPVTQGAPMSVSQREIYSNSRGENFTLSVVTTGDWSVTFNDSWIKVEKKDS
                     KTVSVTTEPNESKTSRKGTLDIVSGAEKITVSVAQESAEDREINTPEGYRLVWHDEFNE
                     GATLGTGWTHEVQKPGWVNNELQEYVNGSVSGKRVTELVDGKLNINCFKASDGKIYSGR
                     VYANVNTGWLYGYFEARIMLPKGKGTWPAFWMMPVGNNYSTNPWPGCGEIDIMEEVGVD
                     ANIVSSSIHCAAYNHTINTQKTASRNIGTAESEFHVYACEWTPDYLKFFVDGTELMTFK
                     NEGSGKNVWPFTYAFYPILNLAWGGDWGGYKGVDESALPITMKVDYVRVFQKK"
     gene            7848..9188
                     /locus_tag="BcellWH2_04355"
     CDS             7848..9188
                     /locus_tag="BcellWH2_04355"
                     /inference="ab initio prediction:Prodigal:2.6"
                     /inference="protein motif:Pfam:PF12388.2"
                     /codon_start=1
                     /transl_table=11
                     /product="Dual-action HEIGH metallo-peptidase"
                     /protein_id="ALJ61572.1"
                     /translation="MKTRYFLFVFLLCFFFSCAEEDNMVISNEMLTESSLQMEQAKIAI
                     YAMGLDTTFISEWDRYYVVEEDILVCKDSVNLSRTLTRQYKTTYHVANFQTITIGVDNT
                     IASNTNWREAVQEVIVLYNKYTGLKFVYTEDDPDIKISKKYISGTNVCASGVFPSSSRK
                     PGEAIIINSNFFKDIDSFLSLNQKIFLLAHELGHNLGLRHTNGGPEGAAGVGLIQIPGT
                     PTTDSDSFMNAGTCGNSWTKFSHYDIVTFNYLWPKARYTVSFANNCCPSITVEVGSLLE
                     RSIAPESDYQIFSGWYEDRELTIPWNYGKRITGNLYLYPKWRYRTSPLVTYRKESYSTN
                     QVSFTLEQTTGVTLTGQVCRGFNEWWEIAKYGGATNVAVGKSSTLIKVMYVNQYIQTSS
                     TVGAFEHTERLVLEAGTYWLSATFPLELGPQNGASLKHGVTVAKIAY"
     gene            9232..11484
                     /gene="bglX_17"
                     /locus_tag="BcellWH2_04356"
     CDS             9232..11484
                     /gene="bglX_17"
                     /locus_tag="BcellWH2_04356"
                     /EC_number="3.2.1.21"
                     /inference="ab initio prediction:Prodigal:2.6"
                     /inference="similar to AA sequence:UniProtKB:P33363"
                     /codon_start=1
                     /transl_table=11
                     /product="GH3"
                     /protein_id="ALJ61573.1"
                     /translation="MKTLKIFSACLFLLPFVSCTQVANKGSDAATEKKVESLLSKMTLE
                     EKIGQMNQISSYGNIEDMSALIKKGEIGSILNEVDPVRINALQRVAMEESRLGIPLLIA
                     RDVIHGFKTIFPIPLGQAASFNPQVAKDGARVAAIEASSVGIRWTFAPMIDIARDPRWG
                     RIAEGCGEDTYLTSVMGAAMVEGFQGDSLNSPTSIAACPKHFVGYGAAEGGRDYNSTFI
                     PERRLRNVYLPPFEAATKAGAATFMTSFNDNDGIPSTGNAFILKNVLRDEWGFDGFVVT
                     DWASASEMISHGFAVGSKEAAMKSVNAGVDMEMVSYTFVKELPELVKEGKVKESTIDEA
                     VRNILRIKYRLGLFDTPYVDEQQTSVMYAPSHLEAAKQAAVESAILLKNDKEVLPLQPS
                     VKTVAVVGPMANAPYEQLGTWIFDGEKARTQTPLNAIKEMVGDKVQVIYEPGLAYSREK
                     NPASVAKAAAAAARADVILAFVGEESILSGEAHCLADLDLQGDQGALITALAKTGKPVV
                     TIVMAGRPLTIGKEVEESTAVLYSFHPGTMGGPALADLLWGKAVPSGKAPVTFPRMVGQ
                     IPVYYAHNNTGRPATRNEVLLNDIAVEAGQTSLGCTSFYMDAGFDPLFPFGYGLSYTTF
                     KYSNIKLASDVLKKDDVLTVTFDLENTGKYEGTEVVQLYIQDKIGSVTRPVKELKRFTR
                     VTLKPGEKKSVSFELPVSELAFWNIDMAKVVEPGDFGLWVATDSQSGEEVFFKVVD"
ORIGIN
        1 atgaaaaagt tattatcagt tttattttta ctgagcttta ccttagcttc tgctgtatat
       61 gcacaagata tacagataaa aggtacggtg gtaagtggtg cggacaatga acccttacct
      121 ggagtaaatg tggtggtgaa aggtaatgcc actacgggaa caatcaccgg tatagacggt
      181 gaattcacct tgtcggtacc ttccggcgca accctttcca tttcttatat aggatttaag
      241 tcacaggata ttccggtgaa cggtagacgt gaactgaaaa ttgttctaca agaagactct
      301 gaagcgttgg acgaagtagt ggtagtaggt tatggtgtgc aaaagaagag tgtggtaacc
      361 gcttctattg ccaaggtaag cagcgaagac attgccggaa aagctcccgt ccgcatggat
      421 aatgcactga aaggactggc tgctggtgta gatgtaactt ctgcttcagg acaaccgggt
      481 gattctcctc gcgtacgtat acgtggtatc ggtactatta ataatagtga tccgctatac
      541 atcgtagacg gtatgcctat tggaggtggc cttgactttg tgaatcctaa tgatatcgaa
      601 tccattgagg ttctgaaaga tgctgcatcc ggagctatct atggtgcacg tgccgccaat
      661 ggtgttatcc tcgttactac taagaagggt aaaatgggta aaactcagat caattacaac
      721 ttctcctatg gctggcagag cgcatggaag caacgtgacg tgacaagcgc tacggactat
      781 gctgtcttgc agaatgagag tcgtgtgaac ggcgggcagg ctccggctta tgctgaccct
      841 tacaatttga tagatggcaa tggacaggca atcaagggat tcggtacaga ttggcaggat
      901 ctggtgttca atgataatgc gccggtggtg aatcatgatg taactatcag tggagcatct
      961 gagaagataa actactatct ctcattggga tattatacac aagatggtat tgttggcggt
     1021 aactacggac aatctaatta tgaccgtctg accattcgtt ctaacacaca gtacaatctg
     1081 attgacgctt ccaaggagcg cagcttcctt aataaactag atttgggcgt aaatatcgct
     1141 tatatgcgca cacacgccac cggtatctcc accaactcag aattcggttc tgctctggga
     1201 tccgccttgt atctgtctcc tatcttgaca cctacattga ccggtgatgc ggcaactgat
     1261 atgattgact attataagac ttatgacttg cctcgtgatg caaacggaaa tccctatact
     1321 gtgcccggtt atggtggcgc ttatcaggag atgaataatc cgctggctat gatgacgttg
     1381 agccctcaga aaaactggtc gcataagttt gtacccaagt tttctcttga cttgcagtta
     1441 tgggataatc tgaaatatca cttcagttac agtgccgaca tgggcttctg gggatatgac
     1501 aaagccacga cttctcgttt ctatctttcc ggcaataata atgcctcaca taccagtgta
     1561 gaagccaata aggagcagaa tgttacttgg cagttggaaa ataccttgac ttatgataag
     1621 actattggca agcatacctt tggtgtggtg ttgggacagt ctgctttaaa gtacaagggt
     1681 gactatttga agggtaatcg ctggaatctg gtgaatccgg ataaaccttc cattgactat
     1741 gctacgggaa acatcgaata tacctacaag acagatggaa acggtgacta tatattggat
     1801 aaagatggaa acaaaatcat atcctctact actgttcagt atggcacatc aggtgctccc
     1861 cgtgtggaac acacaatgtc gtccatgttt gcacgcttta gttataacta cgacgaacgc
     1921 tatatgattc aggctacgat acgtcgtgat ggttcaagcc gttttggtcc taacaataag
     1981 tatggtacat tcccttccgt atcggcaggc tggaatgtga cgaatgaggc atttatggaa
     2041 aatacgcgcg cttggcttac taacttaaaa attcgtgcca gttggggtaa gaacggtaat
     2101 gataatattg cagagtttgc ttatacttcg cttacggcta tgggtaataa tgtgcttctt
     2161 ggtaaagatg ccgtcaagta tatcggatct aaggctcaac gactggccaa tcctgatttg
     2221 aagtgggaag aaagtgaaca gactgacttt ggtatcgata tgggattctt taacaatgca
     2281 ttgacattca gtgccgatta ttatataaag aagaccaatg gtatgattat ggagatgcct
     2341 attccgagtt atgtaggtga aagcaagcct ttgggtaacg tgggtgacat ggaaaatagc
     2401 ggcttcgagt ttgaacttgg ttacaaatgg aatatttcgg atgccaaatt tgctgtcaag
     2461 ggtaatgcca cttatcttaa aaacacattg aagaacttag gtaatgacac cggttatatg
     2521 gattttgatg gtattcaggg attgtccggc ggtggtacac gtggttcaaa cggacagcct
     2581 ttcccgtact tcttcggtta taagactgat ggcgtgttcc aaaatatgga tgaagtccgt
     2641 gcttacgtta ataaggatgg agagatgata atgccgaatg cggttcctgg tgatacacgt
     2701 tttgtggatg tgaatggtga cggaagtatt tctgccgatg accgtaccaa tatcggtaac
     2761 ggtacgcccg actggactta tggcttgaac ttcaatgccg actggaaggg tttcgacttc
     2821 aatattttct ttcagggtgt agccggtgcc gatgttttcg atgccactta tcgtacggat
     2881 gtttcttccg gtaactatcc ttcttggatg ttgggtcgct ggaccggtga gggaacttcc
     2941 aacaagtacc cccgtctggc agtgggtgat gccacaaact ggatggtatc cgacctttat
     3001 gtatgcgatg gctcttacct gcgtctcaag aatatcactt tgggttatac attacccaag
     3061 gctcttaccc gtaaacttac tattgaacgt ttgcgctttt atgtgcaagc tgagaatctt
     3121 gtgacttgga cgaaatattg gggttttgat cctgaaatat cttccggtcc cgacggtatt
     3181 aaatctcttg gtatcgatcg tggtgtttat ccgcaggctc gtacctttac agtaggtgta
     3241 aacgtttctt tctaatctaa aaatcaagaa atatatgaaa acaaataaga tattagcaat
     3301 aggcttactt tctgtcgcca cggtgctggc taccggttgt agtgacagtt tccttgaagt
     3361 ggataatccc acaggtgaac cattggaaga ttattatact acggatgcgc atattcagga
     3421 ggctctgatt gctgcttatg atcctattca ttgggccgac tggggattgg accagtacaa
     3481 tgccctgaac attgatgctg aaatcatggg tgataatttc tgggtaggcg gttccactaa
     3541 aacggatatg cagaactggc acatgctctt caattatgaa ggcaatgaaa attatacgct
     3601 tagttctctc tggacagtgg actactcggg cgtcaagcgt tgcaatgact tgctgaaata
     3661 tctggattgg gctactgatg ttacggcgga aaatcgcaag agctatgaga tgcaagcgcg
     3721 ttgcctgcgt gtgttctact ataatatgtt gtggcattac ttcggcaatg ttcctttcta
     3781 tctggagaat ctttccaagc ctccttatac ggctccgcaa tacacggccg atgatgttta
     3841 caacgagctg attgtggaat tggaagctgt gatagattca aaagtgctgc ctttgaagta
     3901 ctataagact gctaagggag aaaatgatga cagtcaattg gggcgcgtca ctcaggctat
     3961 ggcttatatg atgtatgctg aaatggtgat gtatcagaac gacgaagctc gttttgcaaa
     4021 ggctctcggc tatatgaaag agattatagc agactccaac tttcaattgg tgaccgatta
     4081 tgcctccatc tgggaaacaa acggtgaatg gtgcaatgag tccatttggg aaatcaatta
     4141 cgaacagact aactctgaac gtggttgggg aagtccgttg gctgttggtg gtactgtgct
     4201 tcctacattg atttcgccca atacatttac tgctgattcg gaatggaccg gtgaaggttg
     4261 gggattttta cctatgcgcc tcgaaactta tgagatgttt agcagtacgg acaaacgtcg
     4321 cgatgctact tgctgggacg tgcgcggaac gacgtataaa gaccgctatc aggataccca
     4381 tatctggttg cagaaatatc gtccgtatga ccggaacttt aagagtgccc cattcgacca
     4441 gaacttgaac tacaataata attaccgtta ttatcgttat gctgaaacgt tgctcaatgc
     4501 agctgaatta tctctccgca ccggtggcag tgcaactggt gaagccaaga cgtggctgaa
     4561 tgcagtccgc actcgtgccg gactggcaga actctccaca gctaccgtgg acgatatact
     4621 aaccgaacgt cgccttgagt ttgtgggtga aggtaaacgc tactttgact tggtacgtgc
     4681 cgagaacatc agtggagttt catccaagaa taaggctact acggcacttg ttcccgatca
     4741 atatggttat cgcaccaatt cgtggactct gaagaaaaag catattccta tcgcgcaagg
     4801 tgagttggat tccgatccgg ccttgattca gaacgattat aaatagtttc ccataacttt
     4861 attaaagaat aaacgatatg aaaaatattt ttaaatatat ggcaggggtg ttgattgcag
     4921 gttttgcaat gactgcatgt tcgcccgagg acttttccgg tgcatcacag gacggtctac
     4981 cgaaattggc tgattataag gctgctgtga cagttgacca ggaaaccaat agagtaacat
     5041 tcaatattgt agatgcccaa ggtcagaatc ctaaaggtgt gtatcctata tgggttataa
     5101 atatctctcc cattgtcaag acaacggtta acggttatca gactggctta gtaccccttg
     5161 caggcgagta ttcttactca ttgcaggtgg gaaataaaaa tggtatcagc gatggtacta
     5221 tagagggaac attcactatt aatacaacca gatacgattt ctctgatgta gtttctaaac
     5281 taaccaataa ggctacaaag gaatggcgcg tttacagtgc caaggctgga cacctgggtt
     5341 gtggcgaatc tccaaaagac ccggcgggat ggtggtctgc acctgctgaa gataaagtaa
     5401 gtgaaggtat ttatgatgat cggattactt tcacggcagg cgagaaactt gctgaaggtg
     5461 cttataagta tagtgcgggt gaagatggac tcacattctg taataaaggt gttaccactt
     5521 tgggtgtaac ggccgcagaa gctgattata gcactgcttg tgtgggtgta aacggtgctt
     5581 tgagtgaggc tacttacaac ttgggctaca atgccgaact ggattgcgtg accattacat
     5641 taccggctaa gactttgttc ccgtatatgg ctgatgatgc gcagatgaat ggggcaatga
     5701 cgtacattat aactgatctg aacagcaaga ccatgacttt ggttattgaa ctttccggaa
     5761 tttcctggca gattattctg gtgaacggag atgacgaggc tgtagaagag gcatttgatc
     5821 cggaattggt gaactggtgt gcggtagacg ctcctgaaaa tctgggtgcc ggtttcaata
     5881 caaaggggga gatgacgttc tggtttgcgg ctgctgattg gcagcagata ggtgatcctg
     5941 aattttctta tgccgatggc gtttataccg ttactacaaa ggatgctact gtagaaccat
     6001 ggcaggggca atgtgtaatc ggtgaagttc ctttgactat tgaaggtgaa gagttttatg
     6061 acattgcttg caaggtggta gcaagcgtgt cagtagatcg atttaccgtt aaggtaaaca
     6121 aggatccgga tgttgagggc gatcctaatg ctcttttcgc taaagtggat gtggttttga
     6181 agaaaggaga gaatattctt cgttttgcga aaagaacagg tattaatagt gatggagatc
     6241 ccgtttcttt tgaacaaggc aagtttatcg tcgacttagg cggtactccg gcaggtgtta
     6301 aaattgaaat cagcgacatc attattcaga agcataatcc gaaataatgt atacttagat
     6361 gataggaggg gagaaacttc ttccctccta tatatcatta aaacattcat tgtttttata
     6421 gaacacagat ggatatagta ttgcgttata aataatagat gtatagatga agaaattaaa
     6481 tattatactg ctgtttttat tgctcttcat atcttgtagt aatgaggatg ctggcaattt
     6541 ggtgacagat gacgtgactc tggaatgttc gccggaaaag gtggaaacat caggtgctgg
     6601 cggagtgtat acgctggacg ttacttgtag cgacagtgaa tggactgctt tagccagtga
     6661 tgattgcagt tcatggatcg ctgtaaaagt ggccggttcg cttagcagca aaggaacggc
     6721 gactgttacc gtaagtgcga atacaagtaa ggattcccgc aacggctctg ttatcattaa
     6781 atccggagcg aagcgcgttg tgatacctgt gacgcaaggg gctccaatgt ctgtctcgca
     6841 gcgtgagata tactctaatt ctcgtggcga gaacttcaca ttgtccgttg tgaccacggg
     6901 cgactggagc gtgacgttta acgatagctg gataaaggtc gaaaagaaag atagcaagac
     6961 agtgagtgtc acgacagaac ccaatgaaag caagacttcc cggaagggaa ctttggatat
     7021 tgtttcgggt gcggagaaga ttacggtaag cgtcgctcaa gagtcggcag aagaccgtga
     7081 gataaatacg cccgaaggat atcgcctggt ttggcacgat gagtttaacg aaggcgctac
     7141 tcttggcacc ggctggaccc acgaagtgca aaagcccggt tgggtgaaca atgaacttca
     7201 ggaatatgta aacggttcgg taagcggtaa acgcgtaacg gaattggtag atggtaaact
     7261 gaacatcaac tgctttaaag cttcagacgg caagatctat tcggggcgtg tttacgctaa
     7321 tgtaaatacg ggatggcttt atggctattt tgaagctcgt atcatgcttc ccaaaggcaa
     7381 gggtacttgg cctgctttct ggatgatgcc ggtgggcaat aattactcta ctaatccttg
     7441 gccgggttgt ggtgaaattg acatcatgga agaagtgggc gttgatgcga atatcgtgtc
     7501 gtcttccatt cattgcgcgg cttacaatca taccataaat actcagaaga ctgcatctcg
     7561 caatattggt acggcagagt cagagttcca tgtctatgct tgtgagtgga cacccgacta
     7621 tctgaaattc tttgtagatg gaacagaatt gatgacattc aagaatgaag gttccggcaa
     7681 aaatgtgtgg ccgttcactt atgctttcta tcctattctc aaccttgcat ggggcggtga
     7741 ttggggagga tacaaaggtg tagatgagag cgccttgcct ataacgatga aggtggatta
     7801 tgtacgggta ttccaaaaaa aatagtgtaa ctaataaaat aattgtaatg aaaactagat
     7861 atttcctttt tgtttttctt ctttgcttct ttttttcttg tgccgaagaa gataacatgg
     7921 taattagtaa tgaaatgttg acggagtcat cgttgcaaat ggaacaagcc aagatcgcta
     7981 tttatgctat gggacttgac acaacattta tttctgaatg ggacaggtat tatgttgttg
     8041 aagaagatat attggtatgt aaagatagcg tgaatttatc aagaactctt accagacagt
     8101 ataaaacgac ttaccatgtg gctaattttc agacaatcac tattggtgtt gataatacta
     8161 tcgcttcaaa tactaattgg agagaggctg tgcaagaagt cattgtattg tacaataaat
     8221 atacgggatt aaaatttgta tatacggagg atgatccaga tataaaaatc tctaaaaaat
     8281 atatttcagg aacaaatgta tgtgcaagtg gtgtgtttcc ttcatcttca agaaagccag
     8341 gggaagcgat aatcattaat agtaattttt ttaaagatat agattctttt ttatctttaa
     8401 atcaaaaaat atttttattg gcgcatgaac ttggacataa cttgggattg cggcatacta
     8461 atggtggacc tgagggtgcg gctggagtag gtttaattca aataccagga acgcctacta
     8521 ctgattcaga ctcttttatg aatgctggca catgtggtaa ttcttggact aagttttcac
     8581 attatgatat agttactttt aactatctgt ggcctaaagc tcgatataca gtttcttttg
     8641 caaataattg ttgtccttca ataacagttg aagtaggcag tctattagaa cgctctattg
     8701 ctcctgaatc tgattatcaa atcttttccg ggtggtatga agatagagag ttaaccattc
     8761 cgtggaatta tggaaaacga atcacgggta atctttattt gtatccaaaa tggagatata
     8821 gaacatcacc attagttact tatcgaaagg agtcatatag tactaatcag gtatctttta
     8881 ctttggaaca aactacaggg gttactctaa caggtcaagt ctgtcgtggg tttaatgagt
     8941 ggtgggaaat tgctaaatat ggtggtgcca ctaatgtagc tgtcggcaaa tcatcaacat
     9001 tgattaaagt tatgtatgtg aatcaatata ttcaaacttc tagtacagtt ggagcttttg
     9061 agcatacaga gaggcttgta ttggaggctg gaacttattg gttatctgct acattcccat
     9121 tggaactagg accacaaaat ggagcctcat taaaacatgg ggtgacagtt gctaagatag
     9181 cttattgatt aatgataatc tgtaatcata attatataat ttagttaatt catgaagaca
     9241 ctgaaaatct tctccgcctg cttgtttctc ttgccttttg tctcttgtac gcaagtagcc
     9301 aataaaggta gtgatgcggc aaccgagaaa aaagtagaat ctctcctgtc taagatgacc
     9361 cttgaggaga aaatcggtca gatgaaccag atttcctctt acggtaatat cgaggatatg
     9421 agtgctttga ttaagaaagg tgaaatcggt tccatcttga atgaggtgga tccggtgcgt
     9481 attaatgcgc tacagcgcgt ggcaatggaa gaatcccgtt tgggtattcc tttattgata
     9541 gcgcgtgatg tcattcacgg gtttaaaaca attttcccta ttcccttggg acaagcggct
     9601 tcgttcaatc cgcaggtagc gaaagacggt gcacgggtag cagctattga agcttcgtct
     9661 gtaggtatcc ggtggacttt tgcgccaatg attgatattg cccgcgatcc tcgctgggga
     9721 cgtattgccg aagggtgtgg tgaagatacg taccttactt ccgtaatggg agcagctatg
     9781 gtagaaggtt ttcagggaga ttcgctgaat agtcctactt caattgcagc ttgccctaaa
     9841 cattttgtag gttacggtgc agccgaagga ggacgtgatt ataattccac gttcattccc
     9901 gaacgtcgtc tgcgcaatgt ttatttgcca ccttttgaag ctgccaccaa agcgggggca
     9961 gccacgttta tgacttcatt taatgataat gatggaatcc cttctaccgg gaatgctttt
    10021 attttgaaga atgtactccg tgatgagtgg ggattcgatg gttttgttgt gacggactgg
    10081 gcttctgcca gcgaaatgat aagccatggt tttgccgtcg gttcaaagga agcggcaatg
    10141 aaatctgtga atgcaggagt agatatggaa atggtgagtt acacttttgt gaaggaactg
    10201 ccggaattag tgaaagaggg aaaggtgaag gaaagcacta tcgatgaggc tgttcgtaat
    10261 attttgcgta taaagtatcg tttaggattg tttgatacac cttatgtaga tgaacaacaa
    10321 acatctgtca tgtatgctcc ttctcatttg gaagcagcta agcaagccgc tgttgaatcg
    10381 gctattctgt tgaagaatga taaggaagtg ttgccgttac aaccatctgt gaaaactgtt
    10441 gcagtggtag gacctatggc taatgcacct tatgaacagt tgggtacttg gatatttgat
    10501 ggtgagaaag ctcgtactca gactccgttg aacgctatta aggaaatggt tggcgataaa
    10561 gtacaggtga tttatgaacc gggactagca tatagtcgtg agaaaaatcc ggcaagtgtg
    10621 gctaaagcag ctgccgccgc tgcacgtgca gatgtcattc ttgcttttgt gggtgaagaa
    10681 tctattcttt cgggtgaagc tcactgtttg gctgatctgg atttgcaggg tgatcaggga
    10741 gctttgatta cagctttggc taagacgggt aaacctgtag tgactattgt gatggcgggt
    10801 cgtccgttga ctatcggtaa agaagtcgaa gagtcgactg ctgttctcta ttcattccat
    10861 ccgggcacaa tgggcggtcc tgcattggct gatttgcttt gggggaaggc tgtgccgagt
    10921 ggaaaggcgc cggtcacttt cccgaggatg gtgggacaaa ttcctgtgta ctacgctcat
    10981 aataataccg gacgtccggc tacacggaat gaagtgttgc tgaatgatat tgctgttgag
    11041 gcaggacaga cttcactggg ctgtacttcc ttctatatgg atgcgggttt tgatcccttg
    11101 tttccgtttg gttatggctt gtcgtacacc acatttaagt atagcaacat caaactggcg
    11161 tctgatgtac tgaaaaaaga tgatgtgctg acagtgacat tcgatctgga aaataccggg
    11221 aaatatgaag gaacggaagt agttcaattg tatatacaag ataagattgg ttccgtgacc
    11281 cgtccggtga aagaactgaa acgtttcact cgtgtgacat tgaagccggg tgagaagaaa
    11341 agcgtttcgt ttgaactccc tgttagtgaa cttgcatttt ggaacataga tatggctaaa
    11401 gttgtggaac ccggagactt tgggctttgg gtggcaacgg atagtcagtc cggagaagaa
    11461 gttttcttca aggtagtaga ctga
//
