LOCUS       CP012801               14292 bp    DNA     linear   BCT 16-OCT-2015
DEFINITION  Bacteroides cellulosilyticus strain WH2, complete genome.
ACCESSION   CP012801
VERSION     CP012801.1
DBLINK      BioProject: PRJNA289334
            BioSample: SAMN03852682
KEYWORDS    .
SOURCE      Bacteroides cellulosilyticus
  ORGANISM  Bacteroides cellulosilyticus
            Bacteria; Bacteroidetes; Bacteroidia; Bacteroidales; Bacteroidaceae;
            Bacteroides.
REFERENCE   1  (bases 1 to 14292)
  AUTHORS   Wu,M., McNulty,N.P., Rodionov,D.A., Khoroshkin,M.S., Griffin,N.W.,
            Cheng,J., Latreille,P., Kerstetter,R.A., Terrapon,N., Henrissat,B.,
            Osterman,A.L. and Gordon,J.I.
  TITLE     Genetic determinants of in vivo fitness and diet responsiveness in
            multiple human gut Bacteroides
  JOURNAL   Science 350 (6256), AAC5992 (2015)
   PUBMED   26430127
REFERENCE   2  (bases 1 to 14292)
  AUTHORS   McNulty,N.P.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-SEP-2015) Center for Genome Sciences and Systems
            Biology, Washington University School of Medicine, 4444 Forest Park
            Ave., Saint Louis, MO 63108, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method       :: HGAP 2.0 and Celera v. AUG-2014
            Assembly Name         :: B_cell_WH2_2.0
            Long Assembly Name    :: Bacteroides cellulosilyticus WH2 2.0
            Genome Coverage       :: 209x
            Sequencing Technology :: PacBio; Illumina MiSeq
            ##Genome-Assembly-Data-END##
FEATURES             Location/Qualifiers
     source          1..14292
                     /organism="Bacteroides cellulosilyticus"
                     /mol_type="genomic DNA"
                     /strain="WH2"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:246787"
     gene            1..4473
                     /gene="todS_23"
                     /locus_tag="BcellWH2_04051"
     CDS             1..4473
                     /gene="todS_23"
                     /locus_tag="BcellWH2_04051"
                     /EC_number="2.7.13.3"
                     /inference="ab initio prediction:Prodigal:2.6"
                     /inference="similar to AA sequence:UniProtKB:E0X9C7"
                     /codon_start=1
                     /transl_table=11
                     /product="DBD-Pfam|HTH_AraC,DBD-SUPERFAMILY|0035607"
                     /protein_id="ALJ61271.1"
                     /translation="MKKILYLILGLIGVLSVKAQPDCFFTHYSSEDGLSQNTVMSILQD
                     RKGNIWLATWDGINKFNGYSFKTYKARLDNRIVLSHNRIDHMLEDKYGFLWLQTYDNHA
                     YRFDPRTETFERAPGDDEEGGTANITNIKVLPGGSVWLLTETEGVIRVATDPQDYSLTS
                     QYYSTQSGQFSASRVFQVYEDRAGNEWILSDNGLGMLAPGEKSPVFYFAETAEREKKGG
                     QAFYFCLEHGPEIYFGSDNGRVWRYQKESGQFLLLSLPVSSHIVSINHIDGNEIILTTS
                     KDGFFTYKCDTKKTEHFPASRFPDAPIHGTYVDKASEVWFEQHIPGTVVHFNPHTQVLK
                     REVIAVEPTSTDRSRPAFHAHEDINGMLWVHPYGGGFSYFDRESNSLRPFYNELSGHDW
                     RFSNKIHTAFSDNQGNLWMCTHSKGLEKVTFRPSQFGIVTPVPHDYESLSNEVRALCED
                     ADQNLWVGLKDGKLRIYDKNRVNKGYLTENGTVSHSGTPLRGNVYFILQDSKQNFWIAT
                     KGDGLVKAEKQKDSYHYKLTRYQHQEGDIYSLSDDNVYCVYEDKHGRIWIATFAGGINY
                     MAHSQGGKEIFVNHRNNLKGYPIDYCYKARFITGDDQGHIWIGTTVGALMMDADFKNPE
                     DVKFRHFLRVPDNEHSLSNNDVHWIVSTRNKELFIATFGGGLNKLVSLDESGNACFKSY
                     TVQDGLPSDVLLSIQEDKAGNLWLSSENGISKFIPSKEKFENYADKEIFFRVRFSEAAS
                     EYTASGNILFGASTGIFYFNPDSIGKSNYVPPMVFSKLLVANVDVVPGQGSVLKQGLDD
                     TKELVLSHRENIFTIQFAALDYSAPSEIQYAYILEGFEKAWNYVGKQRVATYTNLPKGH
                     YVFKVRSTNSDGIWTENTRTLDIEILPSFWETPFAYFLYVLFFIMIIVAAVYILFTIYR
                     LKHEVSVEQQMTDMKLRFFTDISHELRTPLTLISGPVEYILGNTKLPDDAREQLQVVER
                     NTNRMLRLINQILDFRKIQNRKMKMQVQRMDVVAFTRKIMANFESVAEEHQIDFLFETE
                     KEELYLWVDADKFEKIVFNLLSNAFKYTPNGKMITVLVREDEKSVSVSVEDQGIGIADN
                     KKKSLFVRFENLVDRNLFNQSSTGIGLSLVKELVEMHKATITVDSKLGEGSCFKVDFLK
                     GKEHYDESVEFLQDDATVGMGVIEQVTDILSEIPESSGEENIEEESEESMDAKGTMLLV
                     EDNSELRLFLRSIFASEYRIVEAVDGMQGWSKALKFLPDIIISDVMMPGKDGITMTREL
                     RADMTTSHIPIVLLTAKTSIESKLEGLEYGADDYITKPFSATYLKARVKNLLTQRRKLQ
                     GIYRDNLMTGNATVDLTEETVEEQGPEMSPNDRKFMDKLVELMEKNMDNGELVVDDLVQ
                     ELAVSRSVFFKKLKTLTGLAPIEFIKEMRIKRAVQFIETGEYSMTQISYMVGINDPRYF
                     SKCFKQKMGMTPTEYRDKGMNKINSSKNT"
     gene            complement(4701..6110)
                     /locus_tag="BcellWH2_04052"
     CDS             complement(4701..6110)
                     /locus_tag="BcellWH2_04052"
                     /inference="ab initio prediction:Prodigal:2.6"
                     /inference="protein motif:Pfam:PF12905.1"
                     /codon_start=1
                     /transl_table=11
                     /product="GH140"
                     /protein_id="ALJ61272.1"
                     /translation="MKRILFYLCFTCFFYQVFSQSHNLPWKNGALQISSNSRYLQHTNG
                     SPFFWLGDTGWLLPERLNRDEAEYYLEQCKQAGFNVVQVQTINGVPAMNFYGQSSMPDG
                     FDFSNINRPGIYGYWDHMDFIIDAAARRGIYIGMVCIWGGLVKSGKMNVEEAKAYGTFL
                     ANRYKDRPNIIWMIGGDIYGNIKTEVWNMLANTIKSIDKNHLMTFHPFGRTLSAEWFND
                     APWLDFNMFQSGHRRYGQSKDDKKTLLPQGTEEDNWRYVEHSLAQKPLRPVIDGEPSYE
                     AIPQGLHDPKEGFWKDNDVRRYAYWSVFAGSFGHTYGHSSIMQFLKPGVNPAYGATKLW
                     YEALKDPGFNQMQYLKKLILAFPFFERVADQSCIADNNGTKYERLIATRGNDYMLVYNY
                     TGRPMKIDLSKIHGKTKKAWWYSPRNAELSYIGEFSSKVETFQPEGGHSNGNDWVLILT
                     DGTRKYIEALQ"
     gene            complement(6135..7409)
                     /locus_tag="BcellWH2_04053"
     CDS             complement(6135..7409)
                     /locus_tag="BcellWH2_04053"
                     /inference="ab initio prediction:Prodigal:2.6"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ALJ61273.1"
                     /translation="MKKLFLVFSILTASITVMGQQPIPVKPRILISTDIGGTDPDDNQS
                     MAHFLMYSEMFETEGLVSSPSYGHGSKQNLLDMIDLYEKDLPKLKKHIKGFPSPDALRA
                     ICKQGRQGAAPFKGYTTATEGSDWIIKCTRKESTRPLWILVWGGLDDLAQALHDAPDIQ
                     NKIRVYWIGGPNKKWSTNSYVYIVENFPNLWFIEANASYRGFITNDKQPGKFNKDYYDE
                     CIRGAGYLGKDYIKYYDGKVKMGDTPSLLYMMDGDPNNPQKESWGGSFEKFTHSPRVIF
                     NRSTTLKDTVPVYAIIEFRIKGPEMNIPADSTCFTMTTDGQDWDGFYLGNGEYAIRYAP
                     KSTAVLTYKITSDIPGFPEQTGEFVVNNTWPGKIDADDYKLGDYWYTDRNDANLFEGKW
                     QGSKTVSKWRKDVLQDWAKRWELLK"
     gene            complement(7634..9205)
                     /locus_tag="BcellWH2_04054"
     CDS             complement(7634..9205)
                     /locus_tag="BcellWH2_04054"
                     /inference="ab initio prediction:Prodigal:2.6"
                     /inference="protein motif:Pfam:PF00041.15"
                     /codon_start=1
                     /transl_table=11
                     /product="Fibronectin type III domain protein"
                     /protein_id="ALJ61274.1"
                     /translation="MKNKFKNIALICGVGLMAFAASCSDLDDEIKSSSYDRLFSPTAVE
                     ARVQNKTNVRLGWTKVLGADSYVIELFANDSLQFEGSPVTTYNEVTDNPYTITGLDGET
                     KYSARIKAVGEKISESKWTGVFFKTDAEQILEAVTDDDITSSTVTLRWPAGTAVTAITI
                     SGGLEETRTLSAEEIAAGTATITGLTYETKYTFNIMNGTKSRGKVTVTTMPDYIPAYPG
                     DDLQAKIDAAEEGATIMLLPSKDGSTNQFIYLDNETGDASTKELTISKNIAIKCLGTKP
                     VEAQIKFVLEGTDGFTTENIKFIGVSADILIKTSNCSGTIIVNNIEASGFGNFVVDPGT
                     NTCKVDEFTVTNSYFHDMCSSKRFVDSQKKKCAIMLFNMKNCTVANSCSGSDFLRFDYN
                     ANAAGMIINFENNTLYKIEATSKGLFYIRSNSNGDKAFTANIKNNVFAEMGEKVFFSQD
                     AKTDNLIFNNNNYFNTPSLVVNPDGGSGKVFDTTGLSLNPEFKDAANNDFTITNETLID
                     KNIGNI"
     gene            complement(9226..11046)
                     /locus_tag="BcellWH2_04055"
     CDS             complement(9226..11046)
                     /locus_tag="BcellWH2_04055"
                     /inference="ab initio prediction:Prodigal:2.6"
                     /inference="protein motif:Pfam:PF07980.5"
                     /codon_start=1
                     /transl_table=11
                     /product="SusD family protein"
                     /protein_id="ALJ61275.1"
                     /translation="MKKLIYISLLASASLFASCEDLLDAPSKSSMDETIIFNTEALADA
                     AVMGIHQSFGETNSYRGRYLAYFGVNTDCEIFNNSGMNNVETDKEGSLVTYSAKPDNTY
                     MNTDNNAWAKLYEAIERANKGIKAMRENSDLTNTNMAQLYGELLTLRAFIYFDLIKAWG
                     DVPARFEPITSETIYVEKSDRMVVINQILADLLEAESYLGWPNENKYTQSTERVSKTFA
                     KGLRARIALFAAGYSQHPDGIRYNLEDAAQRQAMYQIAKDECVSIITQGYNKLGTFEEN
                     FRQLCQETGTAGLESIWEIPFSDGRGRVIYTWGVKHENANQWTALNKGGYNGPTPNLFY
                     DYDVDDVRRDITCIPYKWTGTGTAIKEPNKCFGGWSFGKLRFEWLNRIVTSTNDDGMNW
                     QVMRYADIYLMAAEAINELDNPTSAAPYLKPILDRSYPAAKATAILTAASASKTAFFNE
                     IVDQRKFEFAGEALRKVDLIRWNMLGSKLKETKEKMTRLTNREGEYADLPAKIYYNEGL
                     DAASNDADTYVIYGLNHGETDEEGKAMVDAGKFSTSKSWIYSSEESSIATTTKFISQLY
                     VNDPDTKQFWPIWQVFLDASNGTLTNDYNY"
     gene            complement(11068..14292)
                     /locus_tag="BcellWH2_04056"
     CDS             complement(11068..14292)
                     /locus_tag="BcellWH2_04056"
                     /inference="ab initio prediction:Prodigal:2.6"
                     /inference="protein motif:Pfam:PF07715.9"
                     /codon_start=1
                     /transl_table=11
                     /product="gnl|TC-DB|Q45780|1.B.14.6.1"
                     /protein_id="ALJ61276.1"
                     /translation="MSNKMKNMRAALLFCLVAVISLSVSAQNVTVTGTVTDKTGETVIG
                     ASVVQKGNTSNGTITDIDGNFSLSVPANSTLVFSYVGMTSQEIPLKGKTKVEVVMEDDA
                     QALEEVVVIGYGTAKRKDLTGSVATVSSETLAAVPVASATEALQGKMAGVQITTTEGSP
                     DATMSIRVRGGGSITQSNEPLFIVDGFPVESISDIPPTDIEDITVLKDASSTAIYGSRG
                     ANGVIIVTTKSGKEGKMSVSYNAYYSWKKVANKLDVLSARDYANWQYELGLLTDKADKY
                     SQYFGNYQDLDMYDDVATNDWQDLTFGRTGHTFNHNISLNGGSDKMKYAFSYSHMDDKA
                     IMQMSDFKRDNANLKLSHKPIKNITIDLSARFSRTKINGGGANDANSSLNTDKRLKYAV
                     QYTPFPVPGLSDELNSDNEEPSSLLINPLTSLIDNDTRKERTTYNLGAGFTWEIIMNLR
                     FKSEFGYDDYRYNTDRYYGPSTYYVRNTPSSTNQGKPAVTLTRQSRSTIRNTNTVNYDF
                     KKLIKDEKHHLNALIGQEYVIAKNNKITNTSHGFPSTFTADDCINLMTQGTPFEITNYS
                     DPNDVLLSYFGRLNYDYDSKYLFSGTFRADGSSKFARGNRWGYFPSAALAWRVSSEPFM
                     ESTHNWLDDLKLRFSYGTAGNNNIPSGQLNQEYEAKATTWINGYPSYWAPSKTMSNPDL
                     TWETTITRNLGLDYTLLGGKLSGTLEAYWNTTKDLLILFPTSGTGYDNQYRNMGETENK
                     GFEASVNWIAIDKKNFGLSFGANISFNKNKIKSLGSLKTMSNDLTQSYWASSEIGQDYW
                     IEVGGSVGKMYGYVSDGRYEVSDFERYDEVTETWILRDGVSSSSAVGTARPGMMKLKDL
                     DNSGDANGSDDKRVIGDANPLHTGGFNINARLYGFDLTANFNWSYGNDIYNANKIEYTS
                     TSKYLYRNLTSDMAGGKRWNNVDAAGNLVTNMAQLAEMNQNTTMWSPYTDKYIFSDWAV
                     EDGSFLRLNTLTLGYTMPTTLVKKVGINNLRFYVTAYNVFCLTSYSGYDPEVSTSRRNG
                     SNLTPGVDYSAYPKSRQFVVGLNLNF"
ORIGIN
        1 atgaaaaaaa tcttatatct gatccttggg ttgataggtg tgttgtcagt aaaagcgcag
       61 ccggattgtt ttttcaccca ttattcgtct gaagacggac tttctcaaaa tacagtaatg
      121 agcatcctgc aagaccgcaa gggaaatatc tggcttgcta cttgggatgg cattaataag
      181 ttcaatggtt attcatttaa aacatataag gcacgtcttg ataatcgtat cgtgttgagt
      241 cataatcgta tagatcatat gctggaagac aagtatggct tcctttggct acaaacctat
      301 gacaatcacg cctatcgctt cgatccccgt acggaaacgt ttgagcgtgc gccgggtgat
      361 gatgaagagg gaggcacagc caatataacg aatatcaaag tccttccggg tggttcggta
      421 tggttgctga cggagactga aggggtgatt cgggtggcaa ctgatccaca ggattatagc
      481 ctgacctccc aatattattc tacccaatcg ggacagtttt ctgcctcacg tgtgtttcag
      541 gtatatgagg accgggcagg taatgaatgg atattgtctg ataacggatt agggatgttg
      601 gcacccggag agaaatcacc ggtcttttat tttgcagaga cagcagagcg ggagaagaaa
      661 ggcgggcaag ctttttattt ctgtttggag catggccccg aaatctattt cggatcggat
      721 aacgggcgcg tatggcgcta tcagaaggag agcgggcagt tcttgttgct gagtctgccg
      781 gtttcatccc acattgtgtc aatcaatcat atagatggca atgagatcat actgaccact
      841 tcaaaagacg gattctttac ttataaatgt gatacaaaga agacagaaca cttccctgcc
      901 tcccgttttc ctgatgcgcc gattcatggt acttatgtgg ataaagcatc ggaagtatgg
      961 ttcgagcaac atattccggg tacagtggta cactttaatc cgcatacaca ggtcttgaag
     1021 cgtgaagtaa tagctgtgga acctaccagt acagaccgtt ctcgtccggc tttccatgcg
     1081 catgaagata tcaacggcat gctttgggta catccgtatg gcggtggttt ttcatatttt
     1141 gaccgtgaaa gtaatagtct gcgtccgttc tataatgagt tgtcagggca tgactggcgc
     1201 ttttccaata aaatacatac tgccttttcc gacaatcagg ggaatctatg gatgtgcact
     1261 cactctaagg gattggagaa ggtcactttc cgtccatctc agtttggtat cgtaacgccg
     1321 gtaccacacg attatgagtc attgagcaac gaagtacgtg ccctttgcga agatgctgac
     1381 cagaatttat gggtaggctt gaaagatggt aaactacgga tatatgataa gaaccgtgta
     1441 aataagggct atctgaccga aaacggtact gtgtcgcaca gcggcactcc gttgcgtggt
     1501 aatgtttatt tcatcttgca ggacagtaaa cagaatttct ggattgcaac caaaggggat
     1561 ggcctggtga aagctgaaaa gcagaaagat agctatcact ataagctgac ccgttatcag
     1621 catcaggaag gtgatattta tagtttgagt gacgacaatg tttattgtgt atacgaagat
     1681 aagcatggac gcatctggat tgctacattt gcaggcggca tcaactatat ggcgcacagt
     1741 cagggtggta aagagatttt cgtgaaccat cgtaataacc tgaaaggata tcctattgat
     1801 tattgttaca aggcccgttt tataacaggt gatgatcagg ggcatatctg gataggaact
     1861 accgtgggcg ccttgatgat ggatgcagac ttcaagaatc ccgaagatgt gaagttccgt
     1921 catttcctgc gtgttccgga caatgagcat agcctaagca ataatgatgt gcattggatt
     1981 gtatctaccc ggaataagga actctttatt gcaacatttg gcggaggact gaataagtta
     2041 gtatcgctgg atgagagcgg taatgcctgt tttaagtctt atacggtaca ggacggtctg
     2101 ccttcggatg tattgctttc catccaggag gataaagccg gtaacttatg gctcagttcg
     2161 gaaaacggta tcagtaagtt tattccttcc aaagagaaat ttgagaatta tgccgataag
     2221 gagatatttt tccgggtacg tttcagtgag gcggcttcgg aatatactgc ttcgggtaat
     2281 atacttttcg gggcaagtac aggtattttc tatttcaatc ccgattccat cgggaagagt
     2341 aattatgtgc cgccgatggt tttctccaag ttgctggtgg cgaatgtgga cgtggtgccg
     2401 ggacagggtt ccgtactgaa acagggattg gatgatacca aagaattggt actgtcgcat
     2461 cgggagaata ttttcaccat acagtttgct gcactcgact attccgcacc ttccgaaata
     2521 cagtatgctt atatcctgga aggttttgaa aaggcctgga actatgtagg taaacagcgt
     2581 gtagctactt ataccaactt accaaaaggg cattatgtct ttaaagtccg ttctaccaac
     2641 agtgacggta tatggactga aaacacgcgt acattggaca ttgagatact accttccttc
     2701 tgggaaactc cgtttgctta tttcctgtat gtgcttttct tcatcatgat tattgtagcg
     2761 gcggtgtata tcttgttcac tatttatcgt ttgaagcatg aggtgtccgt cgagcaacaa
     2821 atgacggata tgaaactgcg tttctttact gatatctctc atgaactgcg cactccgctg
     2881 actttgattt cagggcctgt ggaatatata ctggggaata ccaaacttcc ggatgatgcc
     2941 cgtgaacagt tacaggtggt agaacggaat acgaaccgca tgttgaggct tatcaaccag
     3001 atactggact tccggaagat acagaaccgg aaaatgaaga tgcaggttca acgtatggat
     3061 gtggtggctt ttactcgcaa aatcatggcg aacttcgagt ctgttgccga agaacatcag
     3121 atagacttcc tgtttgaaac ggagaaggaa gaattgtatc tttgggtaga tgcggataaa
     3181 tttgagaaga ttgtgttcaa tctgctttcc aatgctttta aatacactcc gaatggaaag
     3241 atgatcacgg tgcttgtgcg cgaagatgag aaatcagttt ccgtaagtgt ggaagaccag
     3301 ggaataggta ttgcagataa taagaaaaag tcgctgtttg tccgttttga gaatctagta
     3361 gaccgcaatc tgttcaatca gtccagcacc ggtatcggtt tgtcattggt gaaggaattg
     3421 gtagaaatgc ataaggcgac cattaccgtt gatagtaagt taggagaggg aagctgcttt
     3481 aaggtggact tcctgaaagg taaagaacac tatgatgaat cggtggaatt cttgcaagat
     3541 gatgctacgg tgggtatggg agttatagaa caagtgaccg atattcttag tgaaataccg
     3601 gaatcttctg gagaagagaa tatagaggag gaatcggaag agagtatgga cgccaaaggg
     3661 actatgttgc ttgtggaaga taattcggaa ctccgtttgt tcctgcgcag catctttgct
     3721 tctgagtaca gaatcgtgga agcagtggat ggtatgcaag gttggagtaa agctttgaaa
     3781 ttccttccgg atatcattat tagtgatgta atgatgcccg gaaaagatgg catcaccatg
     3841 acgcgtgaac tgcgtgccga tatgaccacc agtcatattc ccattgtatt gttgacggct
     3901 aagacttcca ttgaaagcaa attggagggg ttggagtatg gagcggacga ttacatcact
     3961 aagccgttca gtgccactta tctgaaagca cgcgtaaaga atctgctcac acagcgccga
     4021 aagttacagg gtatctatcg ggataacctg atgacgggaa atgcaacggt tgacttaacg
     4081 gaagaaaccg tagaagagca aggaccggaa atgtccccga acgatcgtaa gtttatggac
     4141 aaactggtgg aactgatgga gaagaatatg gataatggag aattggtagt agacgatttg
     4201 gtgcaggaac tggcagtcag ccgttcagtc ttctttaaga aactgaagac actgactggt
     4261 ttggcaccta ttgagtttat taaggaaatg cgtatcaagc gtgctgtgca attcattgaa
     4321 accggagaat attccatgac tcagatctct tatatggtgg gtattaatga tccccgttat
     4381 ttcagcaaat gcttcaaaca gaagatggga atgactccga cggagtatcg ggataaggga
     4441 atgaataaga tcaattcgtc aaaaaataca tgaattcatc aaaacggaca tctttgtagt
     4501 cttgtataag gctgataaac aattgattgc taaataatgc agaaaatact gatttatgga
     4561 gttacatttt gtattttcta tatacttttg cccgtgtcgt aaaggtaaga agatgataat
     4621 tacttgaatt caagaaatta tgactggtta gggttaagag gatgtcttca gggacatcct
     4681 cttgttttta ttaaaactat ctattgcaat gcttctatat acttccgggt tccgtctgtt
     4741 aggatgagta cccagtcatt gccgtttgaa tgaccacctt caggctggaa cgtttctact
     4801 tttgaactaa actcaccgat ataagatagc tctgcattgc gtggtgaata ccaccaagcc
     4861 tttttagtct ttccatgaat cttgctgagg tctattttca tggggcgtcc ggtatagttg
     4921 tacactaaca tatagtcgtt gccacgtgtt gcaatgagac gttcatactt tgtaccgtta
     4981 ttgtcggcta tgcaactttg gtcggctact ctttcgaaga agggaaaagc aagtatcagt
     5041 tttttcaaat attgcatctg gttgaatccg ggatctttca gggcttcata ccataatttg
     5101 gtagcaccgt aggctggatt aactcccggc tttaggaatt gcatgataga gctatgaccg
     5161 tacgtatgac cgaatgaacc ggcaaaaacc gaccagtaag catatctgcg tacatcgttg
     5221 tctttccaga aaccttcctt agggtcgtga agtccttggg gaatggcttc ataagacggt
     5281 tctccatcaa taaccggacg tagtggcttt tgagcaagac tatgttccac atatcgccag
     5341 ttgtcttctt ctgtgccttg tggtaacagt gtctttttgt catctttgct ttgtccgtag
     5401 cgacggtgtc cactttggaa catattgaaa tccagccagg gggcatcgtt gaaccattct
     5461 gccgagagtg tccttccgaa gggatggaaa gtcatgagat ggttcttatc aatggattta
     5521 atggtgttgg caagcatgtt ccagacttcg gttttgatgt ttccatagat atctccgcca
     5581 atcatccaga tgatgttggg gcgatctttg taacggttgg cgagaaaagt accataagcc
     5641 ttggcttctt ccacattcat ttttccactt tttaccagcc cgccccagat gcagaccatg
     5701 ccgatataaa tccctctgcg ggcggcggca tcgatgataa aatccatatg atcccaatat
     5761 ccatatatac ccggtcggtt gatattggag aaatcaaatc catccggcat agacgattgt
     5821 ccataaaagt tcatggcagg tactccgttg atggtttgta cctgtactac gttgaagcct
     5881 gcttgtttac attgttcaag atagtattcc gcttcatccc ggttcaacct ttcgggaagc
     5941 agccaaccgg tatctccgag ccagaagaag ggagagccat tcgtatgctg aaggtaacgg
     6001 gagttgctgg atatttgcaa ggctccattt ttccaaggga ggttgtgtga ttgtgaaaac
     6061 acctgataaa aaaagcaggt aaaacataga tagaatagta ttctcttcat gctattattt
     6121 tttagaatat gtatttattt aagcaattcc caacgcttgg cccagtcttg cagaacatct
     6181 tttctccatt tggataccgt tttacttccc tgccattttc cttcaaacag gtttgcgtca
     6241 tttcggtctg tataccaata atctcctaat ttatagtcat cggcatcaat ctttccgggc
     6301 catgtgttat ttacgacgaa ctctccggtt tgttccggaa atcccggaat atcagaggta
     6361 atcttgtagg ttaggactgc ggtagattta ggagcatatc tgatggcata ttcaccatta
     6421 cccagataga aaccgtccca gtcctgacca tctgttgtca tggtgaaaca ggttgagtca
     6481 gcggggatat tcatttccgg tccctttatg cggaattcaa tgatggcata taccggaacc
     6541 gtatctttca gggtagtact ccggttgaaa atgactcttg ggctatgagt gaatttctcg
     6601 aaactccctc cccagctttc tttctgagga ttattcggat caccatccat catgtaaagt
     6661 agtgatgggg tatctcccat cttgactttt ccatcgtaat attttatata gtcttttccc
     6721 agatatccgg ctccacggat acattcatcg taatagtctt tgttgaattt accaggttgt
     6781 ttgtcattgg ttatgaatcc acgataggaa gcattggcct cgatgaacca aaggttgggg
     6841 aaattctcga caatgtatac ataactattg gtactccatt ttttattcgg tccgccaatc
     6901 cagtatactc ttattttatt ttgaatgtcc ggagcatcat gtagagcttg tgctaagtca
     6961 tcgagtccgc cccatacgag tatccataag ggccgggtac tttcttttct ggtacattta
     7021 atgatccaat cagaaccctc tgtggcagta gtataacctt tgaatggggc tgctccttgt
     7081 cttccttgtt tgcagatggc tcgtaaggca tccggtgacg ggaagccctt tatgtgtttt
     7141 ttcaacttgg gcagatcttt ttcgtatagg tctatcatgt ccagaagatt ctgtttactt
     7201 ccgtgtccat aggagggaga agatactaat ccttctgttt cgaacatctc actgtacata
     7261 aggaagtgtg ccattgattg attgtcgtcc ggatctgtgc cacctatgtc cgtactgata
     7321 agaatgcgag gcttaaccgg aataggctgt tgccccataa cagttataga ggcagttaaa
     7381 atagagaaga ctaaaaagag tttcttcatg atatagattc ttttaatttt aaatgttccg
     7441 tcaatagtgg tttgtactta tgtgtatgca aaaatagaag tttatagcta taaagaggag
     7501 gaaatattgt tccttttgga gtaaatgatg ataatatcac ataaagaaat gattaaaata
     7561 gcaagaaaag ataagaggct gaatttttga attcagcctc ttattctatg atatttataa
     7621 ctttgtctac ctatcagata tttccgatat ttttgtcaat taatgtctca tttgtgatag
     7681 tgaaatcatt gttggcagca tccttgaatt ctgggttcaa tgataagccc gtggtatcaa
     7741 ataccttgcc tgaaccacca tcagggttga ctaccagaga tggagtgttg aaatagttgt
     7801 tgttgttgaa tataaggttg tccgtcttag catcctgact gaagaatact ttttctccca
     7861 tttccgcaaa gacattattc ttgatatttg cagtaaatgc tttatcgcca ttactgtttg
     7921 aacgaatata gaacagacct tttgaagtag cttcaatctt gtagagtgta ttgttctcga
     7981 agttgataat catacctgct gcgttggcat tgtagtcaaa acgtaaaaag tcagaacctg
     8041 aacaggaatt agctacagta caatttttca tgttgaagag catgatggca cattttttct
     8101 tctgtgaatc aacaaaacgt ttgctggaac acatatcgtg gaaataacta ttggtcacgg
     8161 taaattcatc tactttacaa gtgtttgttc ccgggtcaac aacaaagttg ccgaatccgc
     8221 ttgcttctat attattgact atgattgttc cggaacagtt acttgttttg atcagaatgt
     8281 ctgccgatac accgatgaat ttgatgtttt ccgttgtaaa tccgtctgta ccttctaata
     8341 caaatttaat ctgtgcttcc accggcttcg taccgaggca tttgattgca atgttcttgc
     8401 tgattgtcaa ctctttagtc gaagcatctc ccgtttcatt atctaggtag ataaactgat
     8461 tggtggaacc gtctttagat ggaagaagca taatggttgc cccttcttcc gctgcatcaa
     8521 ttttggcttg gaggtcgtca cctggatatg ccggaatata atcgggcatg gtagtaacgg
     8581 ttactttacc acgagatttt gtaccattca tgatgttgaa agtgtatttc gtctcataag
     8641 ttaaacctgt gatagttgca gtgcccgctg ctatttcttc ggcagacaag gtacgggttt
     8701 cttccaatcc tccactaatt gtgatggctg taacagctgt tcctgcgggc catctcaaag
     8761 taacggtgct agaagtgata tcgtcgtccg taacagcttc aagaatttgc tctgcatcgg
     8821 ttttgaagaa aactcctgtc catttagatt cggatatctt ttctccaacg gccttgatac
     8881 gagccgaata tttagtttcg ccatccaatc ctgtaatggt gtatgggttg tcggtaacct
     8941 cattgtaagt ggttacagga gagccttcaa actgtagact gtcattggcg aagagttcaa
     9001 tgacataaga atcggctccc aatactttgg tccaaccgag gcgtacattc gttttgtttt
     9061 gtacccgggc ctccacggca gttggagaga ataggcggtc gtagcttgag cttttgattt
     9121 cgtcgtcaag atcagagcag cttgcagcaa atgccattaa gccgactcca catatcaggg
     9181 ctatattttt gaatttattt ttcatatttg ttcagagtga taagattaat aattataatc
     9241 attggttaat gtgccgttac ttgcatcgag gaacacttgc cagatgggcc agaactgctt
     9301 cgtatcgggg tcgttgacgt aaagctggga gatgaacttt gttgttgtag caatgcttga
     9361 ctcctccgat gagtaaatcc atgatttgct ggtggagaac tttcctgcat ctaccattgc
     9421 tttgccttct tcatcggttt caccgtggtt caagccatag atgacgtaag tatcggcatc
     9481 gttgctggcg gcatccagtc cttcattata ataaatcttg gcgggaaggt cagcgtattc
     9541 tccttcacgg ttggtcagtc gggtcatctt ctcttttgtc tctttcagtt ttgatcctaa
     9601 catattccag cggattaagt cgactttgcg gagagcttct cctgcgaatt caaatttgcg
     9661 ctgatccacg atttcgttga agaaagctgt cttactagca ctggctgctg tcagaatagc
     9721 tgttgctttg gcggcaggat aagagcgatc cagaatcggc ttcagataag gggctgcact
     9781 ggtcggatta tccagttcgt tgatagcttc ggcagccatc aggtagatgt cggcataacg
     9841 cataacctgc cagttcattc cgtcatcatt tgtagaagta acgatacggt tcaaccattc
     9901 gaaacggagt ttaccaaagc tccatccgcc aaaacatttg ttgggctcct tgatggctgt
     9961 gccagtacct gtccatttat aaggtatgca ggtgatatca cggcgtacat cgtccacatc
    10021 gtagtcatag aacaagttcg gggtagggcc attgtatcca cctttattca gtgctgtcca
    10081 ctggttggca ttctcgtgct ttacacccca agtgtagatt acgcgcccgc gaccatcaga
    10141 gaacggtatt tcccagattg attccaaacc ggcagtaccc gtttcctggc acaattgacg
    10201 gaaattctct tcaaaagttc ccagtttgtt atatccctga gtgatgatac tcacacattc
    10261 gtctttagca atctgataca tggcttgcct ttgcgcagca tcttccaagt tgtagcggat
    10321 gccgtcagga tgttgcgaat atccggctgc aaataaggcg atgcgtgcac gcagtccttt
    10381 ggcaaatgtt ttgctgacac gctctgtgga ttgggtatat ttgttttcat tcggccatcc
    10441 cagatagctt tcggcttcca gtaagtcggc aaggatttga ttgataacaa ccatacggtc
    10501 ggacttttca acatagatag tttcggaagt gataggttcg aaacgtgcgg gcacgtctcc
    10561 ccaggctttt atcaaatcga aataaataaa tgcacgtaag gtcaacaatt caccatatag
    10621 ttgggccata ttagtattgg tcaaatcact gttttcacgc atagctttaa tgcctttgtt
    10681 ggcacgttcg atggcttcgt acaattttgc ccatgcattg ttgtctgtat tcatatacgt
    10741 attgtctggc ttggcagaat aggtcaccaa agaaccttcc ttatctgttt ctacattgtt
    10801 cattccggag ttattgaata tctcgcaatc tgtatttaca ccgaaataag cgaggtagcg
    10861 tcctcggtaa gaattagttt cgccaaatga ctggtgaatg cccatgacag ctgcatcggc
    10921 caaggcttca gtattgaaga tgatggtttc atccatggat gacttgcttg gggcatccag
    10981 taggtcttcg caagaggcga atagactggc tgatgctagg agtgatatat atattaattt
    11041 tttcattact ttctattatt tgtagagtta gaaattaaga tttaagccaa ctacgaattg
    11101 gcggctcttt ggataggccg agtaatcgac acccggggtc agattacttc cgttacggcg
    11161 gctggtagat acttccggat cataaccact ataacttgtc agacagaata cgttgtaggc
    11221 tgttacgtag aaacgcaggt tgttgatccc gactttcttc actaacgttg taggcattgt
    11281 gtagcctaag gtaagtgtat tcaggcggag gaatgaaccg tcttcaacag cccagtcgga
    11341 gaagatgtac ttgtcggtat acggagacca catggtggtg ttttggttca tttcggccag
    11401 ttgagccata ttcgttacca aattacctgc cgcatctaca ttgttccagc gtttccctcc
    11461 tgccatgtcg gaagtcaggt tacggtatag atacttcgaa gtgctggtgt actctatctt
    11521 attggcattg tagatgtcgt ttccataact ccagttgaag ttggcagtca ggtcgaatcc
    11581 atagaggcgt gcattgatat tgaaaccgcc ggtatgcaga gggttcgcat caccaatcac
    11641 tcttttgtca tcagaaccgt tcgcatcacc gctgttatcc aagtctttca gcttcatcat
    11701 acccggacgg gctgttccta cagcagaaga agaacttact ccgtctctca aaatccaggt
    11761 ttcggtcact tcgtcatatc tttcgaaatc ggatacttcg taacggccat cgcttacata
    11821 gccatacatt ttgcctacac tgcctcctac ttctatccaa tagtcctgac cgatttcgga
    11881 ggaagcccag taggattgtg tcaagtcgtt ggacatggtt ttcagtgaac ccaatgattt
    11941 gattttgttc ttgttgaaac tgatgtttgc tccgaagctc aagccgaagt tctttttgtc
    12001 gatggctatc cagttaacgg aagcttcgaa acctttgttt tctgtttcac ccatgttgcg
    12061 gtattggttg tcataacctg tacccgaggt agggaacaga atcaacaaat ctttcgtagt
    12121 gttccagtaa gcttccaagg taccgcttag tttgcctccc agcagggtgt agtccaaacc
    12181 gaggtttcgg gtaatggtgg tttcccaagt taagtccggg ttagacattg ttttggaagg
    12241 agcccagtaa gagggatagc cgttgatcca ggtagtagcc ttggcttcgt attcctgatt
    12301 taattgtccg gacgggatat tattattgcc tgcagtacca tagctgaaac gaagcttcaa
    12361 gtcgtccaac caattgtggg tgctttccat aaatggttcg gaagatacac gccaagccaa
    12421 ggcggctgat gggaaatatc cccaacggtt gccgcgggca aacttggaag agccgtcggc
    12481 gcggaacgtt ccgctgaaca aatatttact gtcatagtca taattcaaac ggccgaaata
    12541 agaaagcaat acgtcattcg gatccgaata attggtgatt tcaaaaggag ttccctgggt
    12601 catcaggtta atgcagtcgt ccgcagtaaa ggtgctgggg aagccatgtg aagtattggt
    12661 gattttgtta tttttggcta tcacatattc ttggccaatc aaggcattta agtgatgctt
    12721 ttcgtcttta atcagctttt taaagtcgta gttcacggta ttcgtattac gaatagtact
    12781 gcgactttga cgagtcagtg ttacagccgg ttttccctga ttggtagagg agggagtgtt
    12841 acgtacgtaa taggtactgg gaccataata tctatcagta ttatagcgat agtcatcgta
    12901 accgaattca gatttgaaac gtaggttcat gatgatttcc caagtaaagc ctgcaccaag
    12961 attataagta gtgcgttctt tgcgggtatc gttatcaatt aatgaagtca atggattaat
    13021 cagcaaggaa ctgggctctt cgttgtcgga gttgagttca tcggacaagc cgggaaccgg
    13081 gaatggggtg tattgtacgg catatttcag tcgcttgtca gtattcagcg aactgttggc
    13141 gtcgttggca ccaccaccat taatcttagt acgtgagaaa cgtgcactga ggtcaatggt
    13201 tatgttctta atgggcttgt ggcttaattt cagattcgca ttgtcgcgtt tgaagtcgga
    13261 catctgcatg atggctttat catccatgtg cgaataactg aaagcatatt tcatcttatc
    13321 actaccacca ttcaggctga tgttatgatt gaaagtatgt ccggtgcggc caaatgtcag
    13381 atcttgccag tcgttagtgg ctacatcatc atacatatcc aagtcctgat agttgccaaa
    13441 atactgggaa tatttgtctg ccttatccgt tagcagcccc aattcatatt gccaattggc
    13501 ataatctctg gctgagagca cgtccagttt attagctact ttcttccagc tatagtaagc
    13561 attatagctg acactcattt taccttcttt tccgctcttg gtggtcacaa tgattacacc
    13621 gttggcacca cgtgaaccgt aaatggctgt ggaggaggca tctttcagaa ctgtgatgtc
    13681 ttcaatgtca gtgggaggta tgtcggagat actttctacc gggaaaccgt caacaataaa
    13741 cagtggttcg ttgctctgtg tgatagagcc accaccgcgc acacggatag acattgttgc
    13801 gtcgggtgaa ccttccgtgg tggtaatttg tacaccggcc attttacctt gcaatgcttc
    13861 ggtagcagaa gcaacaggaa cagcagctag tgtctcagag cttacggtgg caacggagcc
    13921 ggtcaggtct ttacgctttg ctgtaccgta accgataacc acaacctctt ccaaagcctg
    13981 tgcatcgtct tccataacta cttcaacttt agttttgcct ttcaggggta tttcctgaga
    14041 agtcataccc acataagaga ataccaatgt ggaattggcg ggaacactaa gggagaaatt
    14101 accatcaata tcggtaatag taccgttgct ggtattccct ttctgtacta cggaagcacc
    14161 gataacggtt tctcccgtct tgtctgtcac agtacctgtt acggttacat tttgcgctga
    14221 tacgctaagc gatatcacgg ctactaaaca gaatagtagc gcggcgcgca tgtttttcat
    14281 tttgttagac at
//
