LOCUS       CP012801               12505 bp    DNA     linear   BCT 16-OCT-2015
DEFINITION  Bacteroides cellulosilyticus strain WH2, complete genome.
ACCESSION   CP012801
VERSION     CP012801.1
DBLINK      BioProject: PRJNA289334
            BioSample: SAMN03852682
KEYWORDS    .
SOURCE      Bacteroides cellulosilyticus
  ORGANISM  Bacteroides cellulosilyticus
            Bacteria; Bacteroidetes; Bacteroidia; Bacteroidales; Bacteroidaceae;
            Bacteroides.
REFERENCE   1  (bases 1 to 12505)
  AUTHORS   Wu,M., McNulty,N.P., Rodionov,D.A., Khoroshkin,M.S., Griffin,N.W.,
            Cheng,J., Latreille,P., Kerstetter,R.A., Terrapon,N., Henrissat,B.,
            Osterman,A.L. and Gordon,J.I.
  TITLE     Genetic determinants of in vivo fitness and diet responsiveness in
            multiple human gut Bacteroides
  JOURNAL   Science 350 (6256), AAC5992 (2015)
   PUBMED   26430127
REFERENCE   2  (bases 1 to 12505)
  AUTHORS   McNulty,N.P.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-SEP-2015) Center for Genome Sciences and Systems
            Biology, Washington University School of Medicine, 4444 Forest Park
            Ave., Saint Louis, MO 63108, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method       :: HGAP 2.0 and Celera v. AUG-2014
            Assembly Name         :: B_cell_WH2_2.0
            Long Assembly Name    :: Bacteroides cellulosilyticus WH2 2.0
            Genome Coverage       :: 209x
            Sequencing Technology :: PacBio; Illumina MiSeq
            ##Genome-Assembly-Data-END##
FEATURES             Location/Qualifiers
     source          1..12505
                     /organism="Bacteroides cellulosilyticus"
                     /mol_type="genomic DNA"
                     /strain="WH2"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:246787"
     gene            complement(1..1461)
                     /gene="pehX_6"
                     /locus_tag="BcellWH2_03074"
     CDS             complement(1..1461)
                     /gene="pehX_6"
                     /locus_tag="BcellWH2_03074"
                     /EC_number="3.2.1.82"
                     /inference="ab initio prediction:Prodigal:2.6"
                     /inference="similar to AA sequence:UniProtKB:P15922"
                     /codon_start=1
                     /transl_table=11
                     /product="GH28"
                     /protein_id="ALJ60312.1"
                     /translation="MKVYILSILFSLSFSLVWSKEYNASFFGIKSDGVTLNTNSIQTGI
                     NYIHKEGGGVLVFNVGRYLTGSIELKSNVAIQLKEGAVLVGSLNPYDYNMEGPCYSMIR
                     AINQKNIAIYGKGIIDAQGRQVSYNIIDQVHKGFIKDPLENDRPRRPRGIHFKQCRGIT
                     IEGITIKNTCDWTQEYEECDSLWVRGITVDNKAYWNNDGIDIVDCQNVLIENSFFDSSD
                     DAVCLKSHKTETACRNVVIRNCTMRSSANGIKLGTMTVGGYENIRIINNKIYDTYRSAL
                     TIATPDGGYARNIVVDSLQAYNTGNAIFLRIGNRTHSNKIGTMDSILISNLYVEIPEGK
                     PDAGYEYEGPIEHMPRNISPASIIGLKGHPITHVTLKNVVINHPGAGKPEIAKVGMTPE
                     ELDRVPELADSYPEFSCFKELPAWGLYLRHVERIVLENVTFIARKKDYRPAIVLDDAHH
                     VSMSKMKIQEPGKKKQQIHIYQSTNITK"
     gene            complement(1464..3677)
                     /locus_tag="BcellWH2_03075"
     CDS             complement(1464..3677)
                     /locus_tag="BcellWH2_03075"
                     /inference="ab initio prediction:Prodigal:2.6"
                     /inference="protein motif:Pfam:PF07971.6"
                     /codon_start=1
                     /transl_table=11
                     /product="GH92"
                     /protein_id="ALJ60313.1"
                     /translation="MKRKECFWWVFAIIGVCFLSIRCSNVKEDYCCYVNPFIGNADNGH
                     TFPGACVPFGMIQVSPESGNGSWRYCSGFNIEDDSIMGFSQNHLNGTGCPDLGDILILP
                     FCGDIQNEKYKSRYEKEHQKAHPGYYSVVLSDFGVEVELTATQRTAMHRYTFRKAEPAH
                     ILVDLQSGIVSKNEQLRTHVIDAEMQLLDQYSIVGKNKVKMWVEREFFYVIKFDKPYIA
                     IEELQPQEGEKAKRLLLSFDLKPGENVQVKVGLSTVSIEGAQEALEKENPDWNFEKVKA
                     QSAEAWNNLLSRIDVSGTEEQKVNFYTSIYHLCIQPNNITDVDGRYRGPNDSILYSPIG
                     EYYSTLSLWDTYRAAHPLYTLLVPEKVNGFVNSMLSHCDTQGYLPIWALWGKENHCMIG
                     NHAIPVIVDAYLKGYKGFDPERAYEAIRKSSLESHPKSDWETYNQYGYYPFDLIPEESV
                     SRTLESCYDDYCVAQMAKALGKKEDYNFFSKRARAYTSLFDPVTKLMRGKDSQGKWREP
                     FDPFRLSHAGTSGGDYTEGNAWQYVWHVQHDVDSLIEMMGGNKAFTAKLDSLFWLENNT
                     VNTGFVSDVTGLIGQYAHGNEPSHHVAYLYNYAGEFWKTQKLIREIFDHFYLPVSDGLC
                     GNDDCGQMSAWYLFSAMGFYPVDPISKEYIIGAPQLKEMILRLEGGKNFIIRAEGLSEE
                     NKYVKAVFLNGKELKRFRIFHHEITDGGILEFIMTDNPSKSFN"
     gene            complement(3683..5752)
                     /locus_tag="BcellWH2_03076"
     CDS             complement(3683..5752)
                     /locus_tag="BcellWH2_03076"
                     /inference="ab initio prediction:Prodigal:2.6"
                     /inference="protein motif:Pfam:PF07971.6"
                     /codon_start=1
                     /transl_table=11
                     /product="GH92"
                     /protein_id="ALJ60314.1"
                     /translation="MRYFSIIFVLCLTLSMVQAQQTSFVNPFIGTSDDHGQTDPSATIP
                     FGMIKPGPETIPRGNGGYDYQSQQLKGFSQTRMSGVGCIGVGGNLLIIPFVGTACKTLK
                     MDKASETAIPGYYSVTLDNQLKVEITTGRTAAIYRFTYPATETAGIKINFKHSYGKHIA
                     EEHSIIGDNAVKGFVRSACTCDLGSYKFYYYIEKDKSTYKPEDNDSELLWKFQTEPNEQ
                     IILKIGLSSVSAEEAEANLKKECSNQSFEQIRTNARIAWENLLGQIQVETSDEDLKTSF
                     YTRLYHACQTPFTINDYSGSYKGSDGKVYSQQLPYYHGWSIWDTYRTKYPLLSIVCPME
                     YKHMISSLAELYKQGKPRSATKTEPFLTTRTEHSIITILDALQKGMFDGSLDELLPLML
                     KEAEDISNDSPDKALERGYDFWGVSELAGKMGNKELKKEFSLRSKEYRPIWLQKFKDIG
                     PTSDIMHGDGLYEGTIWQYRWFVPHDFDWVIATLGSKKKVLSELDYFFENNLFNMGNQP
                     DIHVPFLYYYLGAPWKTQKLVRQILLEPTTNYYGTHEKWEKPYIGKIFNTTPQGYLKEM
                     DDDAGTMSSWFVLSSIGLFPVCPGIPYYWINAPVFDTVTLHPTSQQEFKIHVNRPDAEC
                     IYIQKAILNGKVLNRSWLSYDEIMQGGDLTLELGKLPNKHWGHNTDFIKSLFKK"
     gene            complement(5829..7379)
                     /locus_tag="BcellWH2_03077"
     CDS             complement(5829..7379)
                     /locus_tag="BcellWH2_03077"
                     /inference="ab initio prediction:Prodigal:2.6"
                     /inference="protein motif:Pfam:PF07980.5"
                     /codon_start=1
                     /transl_table=11
                     /product="SusD family protein"
                     /protein_id="ALJ60315.1"
                     /translation="MKKILIYSILLFALCSCDNFLEEDPRGKLTPSSFFSSPEDLDMAI
                     TGMYNKYYQTNARVFRAIYVWCADDVTAHSGGNKSRFSEYDRFNFNSGNTDILEMYQLY
                     YQTIKACNYVINNAERTPVEKSFLEPRLGQAYFLRALNYFMLVRIWGRIPLVTENEINY
                     NTPKAEVNKIYELIESDALTAERMLPDNHKIAPYFQNGINVAPNKGAAKALLASVYMTE
                     AGWPLKKGAEYYDKAAAKYKEIIENEDTYGYILEPDIRTLTKEPEANYSKEIVFGEFHN
                     KTKNYFSGPKSELPEESGGWCDYMVELEFFKSMPEGIRKDAWFLTKVTMTGQERNPETG
                     RYPLLNWDDPATNQKHPYWKKNIESSDWVFNYDDGYYETKGISSASGKTRMIFRYADIL
                     LLYAEAVAYGTKSIDDLAFDCMWRVQERAGVPLISKDVTKEYFQKAVLDERRWETAGME
                     HSCMGRFFTMQRHEILHLQKNYRDAAELSLNPNLTLSEEFYYFPIPDNELLIVPGLKD"
     gene            complement(7404..10751)
                     /locus_tag="BcellWH2_03078"
     CDS             complement(7404..10751)
                     /locus_tag="BcellWH2_03078"
                     /inference="ab initio prediction:Prodigal:2.6"
                     /inference="protein motif:Pfam:PF07715.9"
                     /codon_start=1
                     /transl_table=11
                     /product="gnl|TC-DB|Q45780|1.B.14.6.1"
                     /protein_id="ALJ60316.1"
                     /translation="MKINPLLSLFIVQNQSFKDYFRIMKISLFLLFACALQLLAVNTEA
                     QNAVITFPSNSISVGQLIEEIEKQTDYLVVYSNREIDTNRQVIIQNKSAKVSSYLKETL
                     AKVGIGYKFENDYIILSKNTSLLDQIQQEKITGIVTDVKGEPIIGANVSVIGKSIGTIT
                     DIDGKFTIQASLGNTLQVSFIGYKTQTTKVANKHITIVLQEDMEMLDEVVVIGYGTVKK
                     SDLTGSVSSISQKNIKDQPMTRLDQALSGRIPGVVVITNSGAPEQSTQIRIRGANSIYG
                     GNSPLYIVDGVPNTDLFNNLAPNDIQSIEVLKDASATAIYGSRGANGVILVTTKRGAEG
                     KTNIHLETEQSISTIAKKLDLLSASEYAEFYNEYRREKGANQDFFSPDEITQWKKNGGT
                     DWQDLMFRTAHTQNYKLSISGGIPKLQYLVSMNMMDIEGILKESKSQKFSLRSNITADV
                     TNWLKMNLDVNAVRRKTNKNGPRGGVGTIIADAITYSPTLKLKDEEGNWLRDNINSTKD
                     NPYGRLTQDLDESYTNYLAANLQFMVQLPVKGLSLNFQGAAHYKDYKNRWMKSNAKDLR
                     AQNNSANNNQNDSFDWYNVNQINYAREWKEHKLNLMGAIELSQSTTTGLSNEVANLRTE
                     SVDFWNLSLGDMNLFSNSFSRSSLVSLMGRAMYQFKDRYLLTATIRRDGSSKFQGKNKW
                     GNFPSVAVAWRMSEESFIKNLNIFDVLKLRMSWGNTGNQAIGAYSTLGLLAESKYGWGG
                     TSDYPGYGVSGPATPNLTWEKTTQYDLGLDMAFANNRILANIDLYQKNTTGLLLKKPIP
                     YYDGGGTTWVNLGEVKNRGIEFSLTGIPIQNKNLIWESTFNVSYSKNEVVSLGDETRLH
                     PGTKLDQASLNTAVLQVGKPLGSIYGYIWEGLWRTDEAEEAAKWGQKPGDNKFKEKNVN
                     YKLESDDADIIGQAFPDVILGWNNTIKWKNLDFNLFFQGSLGADRLNLSRYLTNECVSD
                     SRFITSKEGYYNRWTPENQNTKIPNPFSSTINSRFETAQYLEKADYLRLKNISIAYTIP
                     RAKTKFADIRISLSAQNLFTITSYTGYDPEGTMDITSNGGNSDINAGVDGGSYPLPRTF
                     TLGLGFSF"
     gene            complement(10892..11863)
                     /locus_tag="BcellWH2_03079"
     CDS             complement(10892..11863)
                     /locus_tag="BcellWH2_03079"
                     /inference="ab initio prediction:Prodigal:2.6"
                     /inference="protein motif:CLUSTERS:PRK09774"
                     /codon_start=1
                     /transl_table=11
                     /product="STP|FecR"
                     /protein_id="ALJ60317.1"
                     /translation="MDERILKYFQNSLAPNERLLLLREIEKNEELKKQFAEYQNIQALL
                     NLSSHTEDKKEGETSYQHFQKRIKSKKMRIWLVKTMKYAAAILILMISTYQLSIWQMSH
                     KLQDDFQVQTNTLYVPAGQRACISLQDGTVVWLNAQSTLTYPSHFYGKERTVSIIGEAF
                     FEVAKDKNRPFIVAAQDAKIQVLGTKFNVYSYPDSKQIRTSLIEGAVQVFYKSKQVILR
                     PNEESIAQDGKLTVSNIKNPDMLLWRNGIYSFNNERLADIVNKLELYYDVTINIANPKL
                     KDINYTCKFRQRDGIEKILHTIQKIHHFKIEIDKENNVITLK"
     gene            complement(11942..12505)
                     /gene="rpoE_5"
                     /locus_tag="BcellWH2_03080"
     CDS             complement(11942..12505)
                     /gene="rpoE_5"
                     /locus_tag="BcellWH2_03080"
                     /inference="ab initio prediction:Prodigal:2.6"
                     /inference="similar to AA sequence:UniProtKB:Q3IYV6"
                     /codon_start=1
                     /transl_table=11
                     /product="DBD-Pfam|GerE"
                     /protein_id="ALJ60318.1"
                     /translation="MILEKQHIDFEQIYLSYFSKMKRFAREYVLSDEDAENIVQDVFLD
                     FWEKKELLPLPINILAYLFTSIKNRCIDFLRHKIVQKEVENKMQEEYRLTLQMKYYSLG
                     ELDEGIFEKDDVEQLLSKVIDSLPERCREIFLKSKIEGKKQKEIAEEMNISINTVETQM
                     GIAYKKLRNELKDYFPLFIFLYYL"
ORIGIN
        1 ctatttagtg atattagtag attgatatat atgtatctgt tgcttctttt tccccggttc
       61 ctggattttc attttactca tgctgacatg atgtgcatcg tccagtacta tagctggtct
      121 ataatctttt tttcgggcaa taaatgtaac attctctaaa acaattcgct caacatgtcg
      181 aagatagagg ccccacgctg gaagttcctt gaaacatgaa aattcaggat atgaatcagc
      241 caattcagga actctatcta attcttccgg agtcatacca acttttgcta tttccggttt
      301 tcctgcaccc ggatgattga ttaccacatt tttcagtgtc acgtgtgtta tgggatgccc
      361 ttttagccca atgatacttg ccggagatat atttctaggc atatgttcta tggggccttc
      421 atattcatag cctgcatccg gttttccttc gggaatttct acatacaaat tagaaataag
      481 gatagagtcc attgttccga ttttattcga atgcgtacgg ttgcctattc gaagaaatat
      541 agcatttcct gtattatagg cttgcagact atccactact atgtttcggg cgtatcctcc
      601 atcgggagta gctattgtta atgccgaacg ataagtatca taaatcttat tgtttatgat
      661 ccggatattt tcatatcctc caactgtcat agtacctaat tttatcccgt tggcactcga
      721 acgcatagta caattacgaa ttactacatt ccggcatgca gtttcagttt tatgggattt
      781 caggcaaact gcatcatccg aagagtcaaa gaaagaattc tctatcaaaa cattctggca
      841 atcgacgata tcaataccat cattattcca atatgcttta ttgtcgactg taatacccct
      901 gacccatagc gaatcgcatt cttcatattc ctgtgtccaa tcacaggtgt tttttatagt
      961 aatcccttct atagttatgc ctcggcattg cttaaaatga attcctcgcg gtctacgcgg
     1021 tctgtcgttt tccaaagggt ctttgataaa acctttatgt acttggtcga ttatgttgta
     1081 tgatacttga cgcccttgtg catcaattat tccttttcca taaatggcta tatttttttg
     1141 gtttatagct cgaatcatac tatagcaagg accttccata ttatagtcat aagggtttag
     1201 ggaacctacc agcactgctc cttcctttaa ttgtatcgct acgttcgatt tgagttcaat
     1261 gctacctgtt aaataacggc cgacattaaa aactaaaacg cctccccctt ctttgtgaat
     1321 ataattaata ccagtctgga tagagttggt gttcaatgtt actccatcag actttatgcc
     1381 aaaaaaagat gcattatact ctttactcca cactaacgaa aaagacaggg agaaaaggat
     1441 tgataatatg tatactttca taattaatta aatgattttg acggattatc cgtcatgata
     1501 aattctaaaa tacctccgtc tgtgatttca tgatgaaaga ttctaaaccg ttttaattct
     1561 tttccattca aaaagactgc ctttacatat ttattttctt ctgataagcc ttcggcacga
     1621 atgatgaaat tctttccacc ttccagacgt aatatcatct ccttcagttg aggagcacca
     1681 ataatatact ctttactgat aggatctaca ggataaaatc ccatagctga gaacaaatac
     1741 catgcggaca tctgcccaca atcgtcattt ccgcacaaac cgtcggaaac gggcagataa
     1801 aagtgatcaa agatttctcg gataagtttt tgggttttcc agaattcccc tgcatagttg
     1861 tataggtaag ctacatgatg actaggttca ttcccatggg catattgtcc tatgagtccg
     1921 gtcacatcag atacaaaacc tgtatttaca gtattgttct caagccagaa gagtgaatcg
     1981 agttttgctg taaatgcttt atttcctccc atcatctcaa ttaaagaatc tacatcgtgt
     2041 tgcacatgcc atacatattg ccatgcattt ccttcagtat aatcccctcc ggaagttccg
     2101 gcatgtgata gtctgaaagg atcaaaaggt tctctccatt tgccctgtga gtccttcccg
     2161 cgcattagtt tggttaccgg atcaaacagg gatgtatatg cacgggctct tttggaaaag
     2221 aaattataat cttctttctt tcctaatgct tttgccattt gtgccacaca atagtcatca
     2281 tagcaactct ctaaagttct ggaaactgat tcttcaggaa taagatcgaa aggatagtat
     2341 ccatattgat tgtaggtttc ccaatcagac ttcgggtgag attctaatga tgattttctg
     2401 attgcttcat aagctctctc aggatcaaaa cctttatatc ctttcagata tgcatctaca
     2461 ataacgggga tggcatggtt accgatcata caatgatttt ctttacccca taaagcccat
     2521 atgggtaaat aaccctgtgt atcacagtga gataacattg aattgacaaa tccgttaact
     2581 ttctccggta ctaaaagagt atataatgga tgagctgcac gataagtatc ccacaaggat
     2641 agggtagaat agtattctcc tatgggagag tagaggatgc tgtcattagg acctctgtat
     2701 cttccatcca catcagttat attattaggt tggatacata aatggtaaat ggaagtgtag
     2761 aagtttactt tttgttcttc tgtgcctgat acgtctatcc gtgacaacag attgttccag
     2821 gcttcggcag attgagcctt tactttttca aagttccaat ctggattttc tttttctaat
     2881 gcttcctgtg caccttctat gctgacagta gacagaccga cttttacttg aacattttct
     2941 cctggtttta aatcaaatga aagaagaagg cgtttggctt tttctccttc ttgaggttga
     3001 agttcttcaa tagctatata gggtttgtcg aatttgataa catagaagaa ctctctttct
     3061 acccacattt tcaccttgtt ctttccgacg atactatatt ggtctaacag ctgcatttct
     3121 gcatctatta catgagttcg cagctgctca ttcttactta cgattccact ttgaaggtct
     3181 accagaatat gtgccggttc tgcttttctg aaagtataac gatgcatggc cgtgcgttgt
     3241 gtcgcagtca attctacctc cactccaaaa tcagataaaa ctactgaata gtatcctgga
     3301 tgagcttttt gatgttcttt ctcatatcta cttttatatt tttcattttg tatatcacca
     3361 caaaatggta gaatcaatat atctcctaag tcgggacatc ccgtaccgtt caaatgattt
     3421 tgggaaaatc ccatgataga gtcatcctca atattaaagc cggagcaata tctccacgaa
     3481 ccatttccac tttccggact tacttgtatc attccaaatg gtacgcaagc tcctggaaat
     3541 gtgtggccat tatctgcatt accaataaag ggatttacat aacagcaata atcctctttt
     3601 acattactac atcttatgct cagaaagcat actccaatta tcgcaaatac ccaccaaaaa
     3661 cattcctttc ttttcattta atttattttt taaatagtga ctttataaaa tcagtattat
     3721 gtccccaatg tttattagga agctttccta actctagggt caaatctccg ccttgcatga
     3781 tttcgtcata gcttaaccaa cttctattta aaactttacc gtttaaaatt gctttttgaa
     3841 tatagataca ttctgcatca gggcgattta catggatttt aaattcttgt tgagacgttg
     3901 ggtgtaatgt aaccgtatca aagaccggag catttatcca ataatagggt atacctgggc
     3961 agacaggaaa taatcctatg gaagagagca caaaccaaga ggacatggtt ccggcatcat
     4021 catccatttc tttcaagtac ccttgtggag tggtattgaa gattttgccg atataaggtt
     4081 tttcccactt ttcatgtgtc ccataataat tagtggtcgg ttcaagtaat atttggcgga
     4141 ctaacttttg cgttttccat ggcgctccaa ggtaataata taaaaacgga acatgtatat
     4201 caggttggtt tcccatattg aataaattgt tctcaaagaa ataatctaat tcactcaaaa
     4261 cctttttctt gctacccaaa gtcgcaataa cccagtcgaa gtcatgaggt acgaaccaac
     4321 gatattgcca tatagtacct tcgtacaaac cgtcaccatg cattatatct gaagttggac
     4381 caatgtcctt aaatttttgt aaccatattg gtctgtattc ttttgagcgt aaagaaaact
     4441 ctttttttaa ctctttatta cccattttcc ctgcgagttc agaaactccc cagaaatcat
     4501 atcctcgttc caatgctttg tccggtgagt cattggagat atcttctgcc tcttttagca
     4561 tcagtggaag tagctcgtcg agagaaccat caaacattcc tttttgtaat gcatctaaaa
     4621 tcgtgataat agagtgttca gtacgtgttg tcagaaatgg ttctgtcttt gttgcagaac
     4681 gaggcttgcc ttgtttgtat aattccgcaa gtgaggagat catgtgcttg tattccatgg
     4741 gacaaacaat agacaacaga ggatattttg ttcggtaggt atcccaaata gaccaaccat
     4801 gataataggg caactgctgg ctatatactt ttccgtcact tcccttataa ctaccggaat
     4861 aatcattgat tgtgaaaggg gtctggcagg catgatagag ccgcgtataa aatgatgttt
     4921 ttaaatcttc atcagaagtt tctacttgta tttgtcccaa tagattttcc caggcaatac
     4981 gtgcattggt gcgtatctgt tcgaaagact gattcgagca ctcttttttg agattcgcct
     5041 cagcttcttc tgcactgaca gaggataatc ctattttcag tataatttgt tcattaggct
     5101 ctgtttgaaa cttccatagt aattctgaat cgttatcttc tggtttataa gtagatttat
     5161 ctttttcaat ataataataa aatttgtaac tgcctaaatc acaagtgcaa gcagaacgca
     5221 caaatccttt tactgcattg tctcctataa tgctatgttc ttcggcaata tgcttaccat
     5281 aagaatgttt gaaatttatt tttatgccgg cggtctctgt agcaggatag gtaaaacgat
     5341 agatagctgc agtcctacct gtggttattt caactttaag ttgattatct aaagttacgc
     5401 tataatatcc ggggattgca gtttctgacg ccttatccat ttttaaagtc ttgcatgctg
     5461 ttccgacaaa aggtattatc agcaggtttc ctccgacgcc tatacagcct actccagaca
     5521 ttctggtctg tgagaatcct ttcagctgtt gtgattgata atcataacct ccgtttccgc
     5581 gaggtatagt ttctggcccc ggtttaatca tcccgaacgg aatggttgcg gatggatcgg
     5641 tttgtccatg atcatcggaa gtaccaatga aaggatttac aaaagaggtt tgctgagctt
     5701 gaaccataga aagggtcaag cataatacaa atattatact aaagtatctc atattaaatg
     5761 ttttataaat gaaagagggt ttcaaaagaa acgcgaactc ttaaaaccct cattttagaa
     5821 aagtagaatt aatcttttaa tccaggaact attaagagtt cattgtctgg tatcggaaaa
     5881 taatagaatt cttcgcttaa tgttaaattg ggatttaaag aaagctcggc tgcatctcta
     5941 taattctttt gcaaatgaag aatctcatgt ctttgcatag taaagaaacg ccccatacag
     6001 ctatgttcca tacctgcggt ttcccaccgt ctctcatcca gaacagcttt ttggaaatat
     6061 tctttagtga catcctttga aataagtggt actccagctc tttcttgtac tctccacatg
     6121 cagtcaaatg ctaaatcatc aatactctta gttccataag caactgcttc tgcgtacaat
     6181 agtaagatat cagcatatct aaatatcatt ctggttttcc cgcttgcgct tgaaattcct
     6241 ttggtttcat aatacccgtc atcataatta aatacccagt ctgaactttc tatatttttc
     6301 ttccaataag gatgtttctg attggttgcg ggatcatccc aatttagtaa tggatagcgt
     6361 cccgtttctg ggttacgctc ctgcccggtc atcgtcacct tggtcaggaa ccaagcatcc
     6421 ttgcgtattc cttccggcat acttttaaag aattccaatt caaccatata gtcacaccat
     6481 ccgccggact cctctggtaa ttcgcttttg ggtccagaga aatagttttt cgttttgtta
     6541 tggaactctc caaatactat ttccttggag taattagctt caggttcttt agtcaatgta
     6601 cgtatgtccg gttctaatat ataaccatac gtatcttcgt tttcaatgat ttctttatac
     6661 tttgcagccg ccttatcata atattccgct ccttttttca aaggccagcc tgcttccgtc
     6721 atgtaaacag aggctagtaa agcttttgca gcgcctttgt taggagctac attaattccg
     6781 ttctgaaaat agggggctat cttatgatta tccggcagca ttctttctgc tgttaatgca
     6841 tccgattcta ttaattcata tattttattc acctctgctt ttggggtatt gtaatttatc
     6901 tcattctctg tgactagagg tatacgtccc caaatgcgta caagcataaa atagtttaat
     6961 gctcttaaaa agtaggcttg tcccagtctc ggctccagga aagatttctc aaccggtgtt
     7021 ctttctgcat tattaattac ataattgcaa gctttgattg tctgataata gagttgatac
     7081 atttcaagaa tatctgtatt tcccgagttg aaattaaacc ggtcatattc cgaaaaacgt
     7141 gacttattac caccactatg ggctgttaca tcatctgcac accacacata aatggctctg
     7201 aagacgcgag cattagtctg gtaatatttg ttgtacatcc cagttatagc catatccaag
     7261 tcttccggac ttgagaagaa agaggaaggg gtaagtttgc cacgagggtc ttcttccagg
     7321 aaattgtcac aagaacataa agcaaataat aatatgctat aaatcaatat ttttttcatt
     7381 ttgcatctat tttattggtt aaactaaaat gagaatccaa gccccaaagt aaatgttctt
     7441 ggtaatgggt atgaaccgcc atcaacgcct gcgttaatgt cactattgcc gccattgctt
     7501 gtgatatcca tagttccttc cggatcatat cctgtgtaag acgtgatcgt aaacaggttt
     7561 tgagcactca gggagattct gatatctgca aattttgttt ttgctctggg gattgtatat
     7621 gcaatactta tattctttaa tcttagataa tcagcttttt ccaaatattg agcagtttca
     7681 aatctggaat tgattgtcga actgaacggg tttggtattt tagtattttg attttcgggt
     7741 gtccatctgt tataataacc ttctttagag gtgataaaac gtgaatcact gacacattca
     7801 ttggtgagat agcgtgataa attcaaacgg tcagctccca gtgaaccttg aaagaataaa
     7861 ttgaaatcta aattcttcca tttgatggta ttattccatc ctaatattac atcaggaaat
     7921 gcttgtccga taatatctgc gtcatcagat tccaatttgt aattcacatt tttctcctta
     7981 aatttgttat ctcctggctt ttgcccccat ttggctgcct cttcggcctc gtcagtacgc
     8041 cataaacctt cccaaatata tccatagata ctacctaatg gttttcctac ttgcaatacg
     8101 gccgtattga gagaagcttg gtctaatttt gttcccggat gtaatcttgt ttcatctcct
     8161 aaactgacaa cttcattttt tgagtaggat acattaaatg tgctttccca tattaaattt
     8221 ttgttttgaa taggaattcc ggttaaagag aattcaatac ctctgttttt cacttcacca
     8281 agatttaccc aagtggttcc tccgccatca tagtatggta taggtttctt tagtaacaac
     8341 ccggttgtat tcttttgata tagatcgata tttgccagaa ttctattatt tgcaaatgcc
     8401 atatctaagc ctaaatcata ttgagtagtt ttttcccatg tcagattagg agtggcaggt
     8461 ccggaaactc cgtatccggg ataatcactt gtacctcccc aaccatactt cgactcagct
     8521 agaagcccta aggttgaata ggctccaatg gcttggttac ctgtattgcc ccaactcatt
     8581 cttaacttta agacatcaaa aatattgaga ttctttataa aagattcttc tgacattctc
     8641 caggcaacgg caactgatgg aaaatttccc catttattct taccttggaa tttggaagaa
     8701 ccatctcgtc taatagtcgc agtaagtaag tatctatctt tgaattgata cattgcacgt
     8761 cccataagtg aaactaacga agagcgtgaa aatgaattgc taaacagatt catatctccc
     8821 aaactcaaat tccaaaaatc aacagattct gttctcaggt tagctacttc attagacaat
     8881 cctgtagttg ttgattgtga taattctatg gctcccataa gattcaactt atgttctttc
     8941 cattctcttg cataatttat ttgatttaca ttataccagt caaaactatc gttttgatta
     9001 ttatttgcag aattgttttg agctcgtaaa tcctttgcat tcgacttcat ccaacgattc
     9061 ttgtaatctt tataatgggc agcaccttgg aaattcaaac tcaacccttt tactggtaat
     9121 tgtaccataa actgtaaatt tgctgctaga taattagtgt aactttcatc caaatcttga
     9181 gttaatcggc cataagggtt atcttttgtt gaattgatat tatctctcaa ccagtttcct
     9241 tcttcatctt ttaatttcaa ggtaggacta taggtaattg catctgctat aatagttccg
     9301 actcctccac ggggaccatt tttatttgtt tttcgtctta ctgcatttac gtctaagttc
     9361 attttcaacc aattagttac atcagcagtt atattagacc gtaaactgaa tttctgactt
     9421 ttcgattcct tcaaaatgcc ttctatgtcc atcatattca tagataccaa atattgaagt
     9481 ttcggaatac ctcctgaaat agagagttta taattttgag tatgagctgt tctgaacatt
     9541 agatcttgcc agtctgtacc tccatttttt ttccactgag tgatttcatc cggagaaaag
     9601 aaatcttgat tagccccctt ttcccgacga tactcattat agaattctgc atattcactt
     9661 gcacttaata gatctagctt tttggcaatg gtagatattg attgttctgt ttccaagtga
     9721 atatttgtct taccttcagc ccctcttttg gtagtgacca gtattactcc gtttgcacca
     9781 cgagaaccat aaatagcagt tgccgaagcg tctttcagga cctctatcga ttgtatgtca
     9841 ttaggagcca gattgttaaa taaatcggtg ttaggtaccc catctacaat ataaagtggt
     9901 gaatttccac cataaataga atttgcacca cgtatacgaa tttgggtact ctgctccggt
     9961 gcaccggagt ttgttataac aacgacgccg ggaattcttc cgcttaaagc ttgatccaat
    10021 cgagtcattg gctggtcctt tatatttttc tgtgaaatgg aagaaactga acctgtcaag
    10081 tctgacttct tcacagttcc atagccaatt acaaccactt catcaagcat ttccatatct
    10141 tcttgtaaaa caattgtgat atgtttgttt gcaactttgg tggtttgagt tttgtagcca
    10201 atgaatgaaa cttgaagggt atttcctagt gaagcttgaa tggtaaactt gccatctata
    10261 tctgtaattg tacctattga tttacctata acactgacat ttgcacctat aatcggctct
    10321 ccttttacat cagtcactat tcctgttatt ttttcttgtt gtatctgatc taataagctg
    10381 gtatttttcg ataaaataat ataatcgttt tcgaatttat agccaatacc tactttcgcc
    10441 aatgtctctt tcaaatatga agatacctta gcagatttat tttgtataat gacctgccgg
    10501 ttggtatcta tttcgcgatt gctatataca actaagtaat ctgtctgctt ttctatctct
    10561 tctattaact gacctacaga tatagaatta gaaggaaagg ttatgactgc gttttgtgct
    10621 tctgtattta ctgccagtaa ttggagggca caagcaaata gcaagaataa agagattttc
    10681 ataattctaa aataatcttt aaagctttga ttttggacaa taaagagtga taacaaagga
    10741 tttattttca tatctttgta tttagagtga atactaaaat tttttccggt gtttactttc
    10801 tacaggcgac aggtggtggt gcacttgtcg ccttcttgat tataattcta tgttttcatg
    10861 tggataatgt attaagggtt aaacaattgt attactttaa ggtgatcacg ttattttctt
    10921 tgtctatttc aattttgaaa tgatgtatct tttgaatggt atgtagtatt ttctctattc
    10981 catctctttg acggaattta catgtataat ttatatcttt caatttggga tttgcaatat
    11041 tgattgtgac atcataatat agctccaatt tgttaacaat gtcagctaag cgttcattat
    11101 taaagctgta gatgccattt cgccataata gcatatcagg attttttata ttgctgactg
    11161 tcaatttccc gtcttgtgca atgctttctt cattgggcct taatataact tgcttactct
    11221 tgtagaacac ttgaacggca ccttcaatca gacttgtcct gatttgtttg ctatccggat
    11281 agctatatac attgaatttt gttcctaata cttgtatttt cgcatcttga gccgctacga
    11341 tgaaaggtct gtttttgtct ttagctactt caaaaaaggc ttcgcctata atggaaacag
    11401 ttctttcctt tccataaaaa tgcgaggggt aggtcaaggt cgattgagca tttaaccaga
    11461 ccacggtacc atcttgcaaa gatatacaag cacgttgccc ggctggtaca tataaagtat
    11521 tggtttgcac ttggaagtca tcttgtagct tatgtgacat ctgccaaata gatagctgat
    11581 atgtgcttat cattaaaatg agtattgcag ctgcatattt cattgttttc accagccaaa
    11641 tacgcatttt tttgcttttt atccgttttt ggaaatgctg atagcttgtt tctccctctt
    11701 tcttatcttc tgtgtgtgag gataagttca gtaatgcctg gatattctga tactcggcaa
    11761 actgcttttt tagctcctca tttttctcta tttcacgaag aagtagcaac ctctcattgg
    11821 gtgctaggct gttttggaaa tattttaata tacgttcatc catcttttta tgacttaatt
    11881 catagtatag acgaatgtag aaaaagaatc cgctaaaagc aaatcacttt ttttgttcag
    11941 gttacaaata atacagaaag ataaaaagag gaaaatagtc ttttagttcg tttcgtagct
    12001 ttttataggc aattcccatc tgagtttcaa ccgtattaat tgaaatgttc atctcttctg
    12061 ctatttcctt ttgctttttg ccctctatct tacttttcaa aaatatctct ctacatcttt
    12121 caggcagcga atctattact ttagagagca attgttctac atcatctttt tcaaaaatcc
    12181 cttcatctaa ttctcctaaa gaataatatt tcatttgtaa ggtcaatcta tattcttcct
    12241 gcattttatt ttctacttct ttctgcacta ttttgtgccg tagaaagtca atgcaacggt
    12301 tttttataga agtgaataaa taggccagaa tattgatagg tagtggcaat agttctttct
    12361 tttcccaaaa atcgaggaaa acatcttgta ctatattctc tgcatcttca tccgataaga
    12421 catattctcg ggcaaaacgt ttcattttcg agaaataaga aagataaatc tgttcaaaat
    12481 caatatgttg tttctctagt atcac
//
