LOCUS       CP012801               13402 bp    DNA     linear   BCT 16-OCT-2015
DEFINITION  Bacteroides cellulosilyticus strain WH2, complete genome.
ACCESSION   CP012801
VERSION     CP012801.1
DBLINK      BioProject: PRJNA289334
            BioSample: SAMN03852682
KEYWORDS    .
SOURCE      Bacteroides cellulosilyticus
  ORGANISM  Bacteroides cellulosilyticus
            Bacteria; Bacteroidetes; Bacteroidia; Bacteroidales; Bacteroidaceae;
            Bacteroides.
REFERENCE   1  (bases 1 to 13402)
  AUTHORS   Wu,M., McNulty,N.P., Rodionov,D.A., Khoroshkin,M.S., Griffin,N.W.,
            Cheng,J., Latreille,P., Kerstetter,R.A., Terrapon,N., Henrissat,B.,
            Osterman,A.L. and Gordon,J.I.
  TITLE     Genetic determinants of in vivo fitness and diet responsiveness in
            multiple human gut Bacteroides
  JOURNAL   Science 350 (6256), AAC5992 (2015)
   PUBMED   26430127
REFERENCE   2  (bases 1 to 13402)
  AUTHORS   McNulty,N.P.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-SEP-2015) Center for Genome Sciences and Systems
            Biology, Washington University School of Medicine, 4444 Forest Park
            Ave., Saint Louis, MO 63108, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method       :: HGAP 2.0 and Celera v. AUG-2014
            Assembly Name         :: B_cell_WH2_2.0
            Long Assembly Name    :: Bacteroides cellulosilyticus WH2 2.0
            Genome Coverage       :: 209x
            Sequencing Technology :: PacBio; Illumina MiSeq
            ##Genome-Assembly-Data-END##
FEATURES             Location/Qualifiers
     source          1..13402
                     /organism="Bacteroides cellulosilyticus"
                     /mol_type="genomic DNA"
                     /strain="WH2"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:246787"
     gene            1..1551
                     /locus_tag="BcellWH2_02537"
     CDS             1..1551
                     /locus_tag="BcellWH2_02537"
                     /inference="ab initio prediction:Prodigal:2.6"
                     /inference="protein motif:Pfam:PF02055.10"
                     /codon_start=1
                     /transl_table=11
                     /product="GH30|GH30_3"
                     /protein_id="ALJ59776.1"
                     /translation="MKNKRLFTYVFLFGLLVNGSACGSDHNETDFPETPGDETPPSPSG
                     LQAYMLTTTDTRTYDLRESTVEFESQASMSPKNILLNPQQIYQTMQGFGAALTGSSAFC
                     LKLMKQEDRAAFLKRTYSLTEGYGCSYVRIAIGCSDFSLKEYTCCDTPGIENFALTSEE
                     TDYVIPILKEIIAINPDIRILGSPWTCPLWMKDYRKYPVYQNREYTAGQLKPEYYADYA
                     TYFVKWIQAFQVAGIPINAITIQNEPLNNKNSASLVMEWKEQRDFVKVLGPAFEAAGLS
                     TKIYAYDHNYNYDNKSDQNGYPYQIYNDSEAAKYIAGAAYHDYGGNRSELLNVYQRAPE
                     KDLIFTESSIGTWNNGHDLTKTLLSNMESIGIGTINNYCSAVTIWNLMLETDFNGSIPS
                     NNGGQPNRPGGCQTCFGAVDLNMSDLKTIYMNSHYYMICHLSAVVRPGAIRIGTSGYTD
                     NDIAYSAFKNTDGSYAFVIINKSSSDKNIVLTAPDDAGKKHSASCTLQPRSVNSFKWK"
     gene            1602..2999
                     /locus_tag="BcellWH2_02538"
     CDS             1602..2999
                     /locus_tag="BcellWH2_02538"
                     /inference="ab initio prediction:Prodigal:2.6"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ALJ59777.1"
                     /translation="MRNRFLLGMMALSLIGMTSCKDEIDQFDDHGSSTIVSFAGTEKAY
                     MGDSITFDFEVKSGGVKINQAKVQLYYGEEMVSEAFYSLKADGKYSGKVLAPYQKNTPD
                     GEAKVILRIQNERFSNDSKEMTVAIERPKYQTLKLVAANGKEYTMTPVPGKEYEYKARE
                     AFPLDMEASIVAPAYSDGTGNPYLQGNELKFGMDNGKIALNSTKGIGFETTGYGEDGKY
                     EITFNTLTFEGSPFPKFGVRFDTQNKFLEFDGSGNVFYIETEFKKDDIIKISGVKEEYA
                     DYWKNPTWFDLVKEDETLLHFRGRDGKYKLTLNKGMNAIMMEQLEKASSSSTQNATAMW
                     VIGNDKIGFPSYAQNNINWSTDKAFNLVPLTETKYELIMLVGQNVNGVNFKFFGQKGWG
                     LEWKGPGAYTAKEGGDYIKYASDGNFNANATWPSGKYMVMTVETSTSPNELWVKALDEL
                     PSYEMGE"
     gene            3042..6248
                     /locus_tag="BcellWH2_02539"
     CDS             3042..6248
                     /locus_tag="BcellWH2_02539"
                     /inference="ab initio prediction:Prodigal:2.6"
                     /inference="protein motif:Pfam:PF00593.18"
                     /codon_start=1
                     /transl_table=11
                     /product="gnl|TC-DB|Q45780|1.B.14.6.1"
                     /protein_id="ALJ59778.1"
                     /translation="MKKRYYIAAMFALGLVAQPAILRANAADEANSIAAVQQQKQRISG
                     LLTDSNGDPIIGATIRVQGTTNRGVISDVEGRYSIEAAPGEVLEFSYIGFVSVEHRVKA
                     DETTFNLRMEMDAIATEEVVVVGYGKQKKESVVSSMSTVGPAQLSVKSANLTNNIAGKL
                     SGLIAVQRSGEPGWDDAQFFIRGISSYAGGTDPLVLVDGVPRKMNDIDVDEIETFSILK
                     DAAATAVYGAEGANGVVLITSKRGKSQKTVVSMSAEYGYSTPLRLPNLMNSYDYLSLYN
                     EADWNSNGNPRANYTAPVSDADLEKYRSGVDPDLYPDADWMSMLRDHTSSQRYTINFRG
                     GGDRVRFFVSGAYYTQDGVYKEKKNADYDSNINFDRYNLRSNIDFELSKTTRMSVDMSG
                     QYINRVAPSKKAEDIFGGMTLQPVHLYPQIYSDGSASQHPNYDNSGLRQNPYNFLYFSG
                     YSKSWDATFQSKVLLEQDLDFITKGLSIRGSVSFDANSNQYVNRTMSAATFAATGRDAD
                     GNLIFKSLESGSALSNPSSGSSGGEKKIYIEASLNYKRNFSNKHDVTGLLLYNQKETQK
                     QNKSGLQLLPYRKQSIVGRGSYTYDNRYTIEGSFGMTGSENFAPGHRWGIFPAVGGAWY
                     VSHEKFFEPVQKVISTLKLRASYGRTGNDQIKINNEDLRFPYQEAMNTDAGGLNLGISG
                     ISNGNAQNWFGGLSENRAYYANLRWEIEDKTNFGFDLGLLNGQIDLSMDYFSNRRKDIL
                     ITRNTIPSMSGLQSNPTQNYGIVSNKGLDGNLTFKQHVGDVNLTFRANYTYAKNKIVET
                     DEIKHRYSYQDLTGMSLWTPYLYIADGLYTPDDFNITIDPVSGAESYQLKSGMADPGAS
                     VAPGDIKYRDLNEDGVINDDDKTYRNGYLDKTPRSVYGLSLNAEWKGFFAGIFFQGVTG
                     CSINLMSKASNFMPFNQGKDASSARMEAMSRWKASDPYNDNVLYPRLRNNTFAHNLQAS
                     TWWYRDASFIRLKNVEFGYQFNKKQLKSLRLTNLRLYVQGTNLKTWDHVKYWDPELGDA
                     NSGAKYPISSTWTFGAEVTF"
     gene            6269..8245
                     /locus_tag="BcellWH2_02540"
     CDS             6269..8245
                     /locus_tag="BcellWH2_02540"
                     /inference="ab initio prediction:Prodigal:2.6"
                     /inference="protein motif:Pfam:PF07980.5"
                     /codon_start=1
                     /transl_table=11
                     /product="SusD family protein"
                     /protein_id="ALJ59779.1"
                     /translation="MKLKNLLYAAVGSAALAFSTASCSDYLDISGEFNASLGIDEVWSN
                     ASYTRNWYGVIYRHLMEYSETGSEVSAFKNPWSNLCGEIASEKASSRDVMMAGFTAASG
                     NYHRWANFYKDVRQAMIFIERAQDQGVGDPTSTDKLTAEEIARMKDECRFMIAYYYFSM
                     FELYGPACIVTEIDDAAEPHITDYDRATVDEMVNHIDGILAPLCDPAQSKLPESVITSY
                     ADNTYNFNTNEVVRPTIVVAKALRAKLWMYAASKLFNGGDGSEYYQGLQKLQNSKGEYI
                     FPQSKDPQKWVTARDRVKDLIDYAEAQHHALYRVMANGVEQPDRSVYNLFQVYNEEILW
                     CSTNNSYSDQYKMEKRTNPRDVNSCYGTIGPSQDAVDMFFMGNGLAINDPNSGYDETGF
                     GAVENHCYDPDYKDKKTDQNISNMYANREPRFYASVVYQGRSWFKKWMNGNPNYIVDFS
                     AGGGNDLSNGDNVKTGYMLGKFKNRTVNHASGDTQSWKRVSIIYRLAEFYLFYAEALNE
                     TDPSNPDIIKYIDMVRERAGIPGYQTMNDNGIKTGIIGNYDKQFDAIQHERYVELYCEG
                     QRYFDIRRWMICGDKDRIGCDQTRFYGMNMKGSKDKTPGEPTSYYTRTKVENRQWTDKL
                     YLYPIHQNVIELANGRIPQNYGW"
     gene            8384..11050
                     /gene="lacZ_13"
                     /locus_tag="BcellWH2_02541"
     CDS             8384..11050
                     /gene="lacZ_13"
                     /locus_tag="BcellWH2_02541"
                     /EC_number="3.2.1.23"
                     /inference="ab initio prediction:Prodigal:2.6"
                     /inference="similar to AA sequence:UniProtKB:P26257"
                     /codon_start=1
                     /transl_table=11
                     /product="GH2|CBM57"
                     /protein_id="ALJ59780.1"
                     /translation="MRKEKKYRIGTYLILIPAILFLFPKVYAQHESKTINDSWKFYQGE
                     CKAAASATYDDSAWNSIHLPHTWNTDAYTEKKYYQGTGWYRRTLTLPQNWQTKQVFLKL
                     DAASKAATIYMNGRKIGEHNGGYTACTFDITPFCSFDAPNSLAIHVDNARQDIPPISAD
                     FTFFGGIYRDVWLTAVPKQHFHLTNYGSEGIFISTPQVSEEKGTILIRGEIKNDAEQKA
                     SLELEHIIYNPDGSIAQTQKQSIQIKGGELYSFRTETSPILSPRLWAPEAPHLYRVESI
                     LRDKKTKAILDHSNHHTGFRWFSFDGKTGFSLNGKPYKLRGICRHQDQKPIGVALTDEM
                     HRRDMKLMKEMGANFIRISHYPQDDALLEMCDKLGMLAWEEIPIIDIVPDTPGYAENCE
                     NNLREMIRQHYNHPSIITWGYMNEILLVTQRRYKKEEELKPVLERTLSLANRLEKVLKE
                     EDSTRVSTMAFHGSNSYNEVGLGNITDIVGWNLYQGWYGGDLTGFERFLTEQHKKHPSH
                     PMIVSEYGAGSDKRLHSLQPHAFDFSIEYQQKYLEHYLPILEETPYICGGTHWNFIDFS
                     SALRDESMPRINNKGLVYSDRSPKDVYYYYKAAWRQNIPVLHIASRDWTHRSGVQHGKA
                     PVPLPVKVYTNLPEVELFIDGKSLGKQKTENYTVTFQVPFSRKKHFIFAQAENKESDQS
                     ISMIEDALHINFTPIPANLNETNLRNLELAVNVGSNCFYTSDESQLTWLPDQPYTESSW
                     GYIGGESRNSQTQVENTHDGPLFQTLRNEIEGYCFDVPNGVYEVEFLFTDIFRENAATV
                     YQLGRESGVESRENIFDIVINGESVEENFSPCRESGYFHTLRKRYNITNFRNKIEIRFP
                     VRNGKSFLNGIKLRKLY"
     gene            11069..13402
                     /gene="ugl_3"
                     /locus_tag="BcellWH2_02542"
     CDS             11069..13402
                     /gene="ugl_3"
                     /locus_tag="BcellWH2_02542"
                     /EC_number="3.2.1.180"
                     /inference="ab initio prediction:Prodigal:2.6"
                     /inference="similar to AA sequence:UniProtKB:Q8DR77"
                     /codon_start=1
                     /transl_table=11
                     /product="GH88"
                     /protein_id="ALJ59781.1"
                     /translation="MRAKICLVITSLLLAVVSIHAQSIWDGKHLERVKQSLHQPYFSAA
                     YQELISGADRLLDVRPLSVMLKEKTPGSGDKHDYMSQARYYWPDPSKPDGLPYISHDGK
                     SNPELDKLDRNRLGETAQRVTTLALAWYFSGDEKYAQKATELIRVWFFNKDTRMNPNLE
                     YAQMIPGHNNNKGRCYGVIDTYSFVEMLDAVQLLEKSEAFTPKDAKQLKTWFGKLLTWI
                     LNSPQGQEEARQANNHSTAHDAQVIAFAMYAGNMKVAREVINAIPRKRLFTQIEPDGKQ
                     PHELRRTLAFGYSQFNLSHFIDIFMMARKIGISIDNATSEDGRSFYKAMDFLVPYVGKD
                     VKAWPYQQISEWKYKQQEFCKDLYRTFLLNPERKDYLKLYKTHRIIDWKDRFNLLWMEA
                     DDVDNAYAFACGQLQFAMQCAAKARKEADNQCKHRVIPRSINKDGSLRMIHPHDWCSGF
                     FPGSLWQVYAYTNDDFWRQQAISNTWLIEEAKWHKGTHDLGFMMNNSFGKAYQLTGERS
                     YKDVVLQSAKTLITRYNKKVKSIRSWDHNRDKWKFPVIIDNLMNLEMLFWATQETGDSI
                     YWKVAVNHANTTMKNHFRPDYSSFHVVDYDPETGEVRARQTAQGYADDSFWSRGQAWAL
                     YGYTMCYRFTKNPAYLQQARHIADFFFGLPNLPEDMVPYWDMKAPGIPDIPRDASAAAI
                     MASALYELRTYVSAEDGNRYQNIADKIVDSLNQHYQAEPGTTYGFLLLHSTGHHPGGDE
                     IDVPINYADYYYLEALARKEALKQ"
ORIGIN
        1 atgaaaaaca aaagactatt cacttatgtg tttcttttcg gcctactggt caacggtagt
       61 gcatgcggat cggaccacaa tgaaacagac tttcccgaaa cgcccggcga tgaaactccg
      121 ccctccccta gtggtctaca agcctacatg cttaccacca ctgacacccg tacctatgat
      181 ttaagagaat ccaccgtgga atttgagtcc caagccagca tgtcgcctaa aaacatccta
      241 ctgaatccac agcaaatcta ccaaactatg cagggattcg gagcggcact tacaggatcg
      301 tcagctttct gcctaaaact aatgaaacag gaagatcggg cagcattcct caaaagaacc
      361 tattcgctaa ccgaaggtta tggatgtagc tatgtacgca ttgccattgg ctgttccgac
      421 ttctccttga aagaatacac ctgttgtgac acacctggta tagaaaactt tgctctgact
      481 tcagaagaga cagattacgt aatacctatc ttaaaggaaa ttattgctat caacccggac
      541 atccgcatac tgggttcacc ctggacttgt cccttatgga tgaaagacta ccggaaatac
      601 cctgtctacc aaaatcggga atacaccgca ggacaactaa aacccgaata ctatgctgac
      661 tatgccacct attttgtgaa gtggatacag gcatttcagg tagctggtat tcccatcaat
      721 gccatcacca tacagaacga accactcaac aacaagaact cagcctcact ggtgatggaa
      781 tggaaagaac aacgtgattt tgtgaaagta ctgggtcctg cttttgaggc tgctggactt
      841 tccaccaaaa tatacgctta cgaccacaac tacaattatg ataacaaaag cgaccaaaac
      901 ggttatccct accagatata caacgattcc gaagccgcta agtatatagc aggagcagcc
      961 taccatgact atggaggtaa tcgcagcgaa ctgctcaacg tctaccaacg agctcctgag
     1021 aaggacctga tcttcacaga atcgtctatc ggcacctgga ataacggaca cgacttgacc
     1081 aaaactctcc tttctaatat ggaaagtatt ggtataggca ccatcaataa ctattgcagt
     1141 gcagtgacca tctggaacct gatgcttgaa acagacttca acggaagcat acccagtaac
     1201 aatggtggac aacctaaccg ccccggcgga tgtcaaacct gcttcggggc tgtagaccta
     1261 aacatgagtg atcttaaaac tatctacatg aactcgcact actatatgat ctgccacctg
     1321 tcggcagtgg taagacccgg tgccatacga attggtacaa gcggctacac agacaatgac
     1381 atagcctaca gtgctttcaa gaatacagac ggaagttatg cctttgtcat catcaacaaa
     1441 agcagttcgg acaagaacat tgtacttacc gcccccgatg acgctggtaa gaagcactcg
     1501 gcaagttgca ctctgcagcc gcgctcagta aactctttca agtggaaata acagagattc
     1561 aaacataata aatcactttt ttaattttaa atttataaat tatgagaaat cgatttttgc
     1621 tcggcatgat ggcactcagc cttataggta tgacatcatg caaagatgag attgaccagt
     1681 tcgatgatca tggcagctcg actatcgtat cctttgcagg cactgaaaaa gcctacatgg
     1741 gcgatagtat caccttcgac tttgaggtga agagcggagg cgtgaaaatc aaccaggcca
     1801 aagttcagct ctattatgga gaagaaatgg tatccgaagc cttctacagt ctgaaagccg
     1861 acggaaaata cagtggaaaa gtgctggctc cctaccagaa aaacacgcct gacggagaag
     1921 caaaggttat actgcgcatc caaaatgaac gtttcagcaa tgacagtaag gaaatgaccg
     1981 ttgctataga gcgtccaaaa tatcaaacat tgaaacttgt ggctgccaat ggcaaggaat
     2041 ataccatgac tcctgttccc ggtaaagaat atgaatacaa agcacgtgag gctttcccac
     2101 tcgacatgga agcatctatc gtagcaccag cttattccga tgggacaggt aatccttatt
     2161 tgcagggcaa tgaactgaaa tttggtatgg acaatggcaa aattgccctc aattccacca
     2221 aaggcatcgg ctttgaaacc acaggttacg gtgaagacgg caagtacgaa atcacattca
     2281 ataccctgac tttcgaaggt agcccattcc caaaattcgg tgtacgtttc gacacccaga
     2341 ataagttcct ggaattcgat gggtcgggca atgttttcta catcgaaacc gaatttaaga
     2401 aagatgacat catcaaaatc agcggtgtca aagaagaata tgctgattat tggaagaacc
     2461 ccacttggtt tgacctcgta aaggaagacg aaactctgct ccatttccgc ggaagagacg
     2521 gcaagtataa actcactctg aacaaaggca tgaatgcaat tatgatggaa cagttggaaa
     2581 aagcttcttc atcaagtaca cagaatgcca ccgctatgtg ggtgattggt aatgataaga
     2641 taggattccc gtcatatgcc cagaacaaca taaactggag tacggacaaa gcattcaacc
     2701 tggttccgct caccgagacc aaatatgaac taatcatgct tgtaggacag aatgttaacg
     2761 gagtcaactt caagttcttc ggacagaagg gatggggact ggaatggaaa ggtcccggag
     2821 cctataccgc aaaagaaggc ggcgattata tcaaatatgc cagtgacggc aacttcaacg
     2881 ccaatgccac ctggccatcc ggcaaatata tggtgatgac cgtagaaacc agcaccagcc
     2941 cgaacgagct ttgggtgaaa gctttggatg aactcccctc atacgaaatg ggcgaatgac
     3001 agactttctt aaagtataga taaacaatta agtatagata tatgaaaaaa agatattaca
     3061 tagcagccat gtttgccctt ggtttggtag cccagcctgc catcctacgt gccaacgctg
     3121 ctgacgaggc taacagcatt gcggctgtac agcaacaaaa acaacgcatc agcggtttgc
     3181 tcaccgattc caatggtgac cctatcatcg gtgccaccat cagagtgcaa ggtaccacta
     3241 atcgcggcgt tatcagtgac gtcgaaggac gatactccat cgaagcagct cccggcgaag
     3301 tactggaatt cagctacatc ggattcgtca gtgtagaaca cagagtgaaa gctgacgaaa
     3361 ccactttcaa cctccgaatg gagatggatg ccatcgctac ggaagaagta gtagttgtgg
     3421 gatatggtaa acagaaaaaa gagagcgtag taagctccat gtccaccgta ggaccagctc
     3481 aattgagtgt aaagagtgcc aaccttacca acaacatcgc cggtaagctg tctggtttga
     3541 ttgccgtaca gcgttcgggc gaaccgggtt gggatgacgc acaattcttc atccgtggta
     3601 tcagctcata tgccggtgga acagacccat tggtactggt ggacggcgta ccccgtaaga
     3661 tgaacgatat cgacgtagac gaaatcgaaa cattctctat cctgaaggat gccgccgcaa
     3721 cggccgtgta tggtgctgaa ggtgccaacg gtgtggtatt gattacttcc aaacgtggta
     3781 aatcacaaaa aacagttgtc agcatgtcgg cagaatacgg ctactcgaca ccgctccgcc
     3841 tgcccaacct catgaactct tacgactatt tgagcctata caacgaagca gactggaaca
     3901 gcaacggtaa cccgcgcgcc aactatacag caccggtgag cgacgctgat ctggaaaaat
     3961 atcgcagcgg cgtagaccct gacctctatc cggatgcaga ctggatgagt atgttgcgtg
     4021 accacaccag cagccagcgc tataccatca atttccgcgg tggtggtgac cgcgtacgct
     4081 tcttcgtatc aggtgcctac tacacacaag acggtgtata caaggagaag aagaacgccg
     4141 attacgattc aaacattaat tttgaccgtt acaacctgcg ttccaatatt gacttcgaat
     4201 tgagcaagac tacccgtatg tctgtggata tgtcaggaca gtacatcaac cgtgtagctc
     4261 cctccaagaa agcggaagat atcttcggcg gcatgactct gcaacctgta cacctctatc
     4321 cgcaaatcta ttctgacggt tcagcttcac aacatcctaa ctatgataat tcaggtcttc
     4381 gtcaaaaccc ctacaacttc ctctacttca gtggatacag caaaagttgg gacgctacat
     4441 tccaaagtaa ggtattgctg gaacaagacc tggacttcat cacaaaggga ctttcgataa
     4501 gaggtagtgt cagtttcgat gccaactcca accaatatgt caaccgcacc atgtctgccg
     4561 ctacatttgc agctaccgga cgcgatgccg acggcaatct gatattcaaa tcactggagt
     4621 caggctctgc attgagtaat ccctcaagcg gttcatccgg cggtgaaaag aaaatctaca
     4681 tcgaggcatc gcttaactac aagcgtaact tcagcaacaa acatgatgtg acgggcttgc
     4741 tgctgtacaa ccagaaggaa actcagaagc agaacaaatc cggtctccag ttacttccct
     4801 atcgcaaaca gagcatcgta ggtcgtggtt cttatactta cgacaaccgc tacaccatcg
     4861 aaggcagctt cggtatgaca ggtagtgaaa actttgctcc gggacaccgt tggggtattt
     4921 tccccgctgt gggtggagcc tggtatgtga gccatgaaaa gttcttcgaa cctgtgcaga
     4981 aagtaatcag tactctgaag ttacgcgcat cctacggacg taccggtaac gatcagataa
     5041 agattaacaa tgaagatcta cgttttccct accaggaagc catgaacacc gatgccggcg
     5101 gtcttaactt aggtatctcg ggcatctcta atggtaatgc acagaactgg ttcggtggac
     5161 tgagtgaaaa ccgcgcctac tacgccaacc tgcgttggga gattgaagat aaaaccaact
     5221 tcggtttcga cctcggtctg ctgaacggac agatcgacct ctctatggac tacttctcca
     5281 atcgtcgtaa agacatcctg attacccgta atacgattcc ttcgatgagt ggtttgcaat
     5341 ccaacccaac tcagaactac ggtatcgtaa gcaacaaagg tctggatgga aacctgacat
     5401 tcaagcaaca cgtaggcgat gtgaatctga cattccgcgc caactacacg tatgccaaga
     5461 ataagattgt agaaactgat gaaatcaaac atagatacag ctaccaagat ctcacgggta
     5521 tgtcattgtg gactccttac ctctacatcg ccgacggtct ttatacaccc gatgacttca
     5581 acatcaccat cgaccctgtg agcggtgccg aaagctacca actgaaatcc ggaatggccg
     5641 atccgggagc atccgtggca cccggtgaca tcaagtatcg ggacttgaac gaagacggtg
     5701 tcatcaacga cgatgacaag acctaccgca acggctatct ggacaagacc ccgcgtagcg
     5761 tatacggtct ctcgttgaat gccgagtgga aaggattctt cgccggtatc ttcttccaag
     5821 gcgtgacggg ctgttccatc aacctgatga gcaaagcatc caacttcatg ccgttcaacc
     5881 aaggcaagga cgcttcttcc gcacgtatgg aggctatgag ccgctggaaa gcatccgacc
     5941 cctacaacga caatgtgctt tacccccgtc tgcgcaacaa tacctttgca cacaacttgc
     6001 aagcaagtac ctggtggtat cgcgatgcca gcttcatccg cctgaagaac gtagagttcg
     6061 gttatcagtt caataagaag caactgaagt cactacgtct caccaacctg cgcctctacg
     6121 tgcaaggcac caacctgaaa acttgggatc acgtgaagta ctgggatccg gaattgggtg
     6181 atgcaaactc aggtgccaaa taccccatct ccagcacatg gacctttgga gcggaagtta
     6241 cattctaaac atttaattaa taaacgatat gaaactgaaa aatttactat acgcagccgt
     6301 cggctctgcc gcccttgcat tcagcacagc atcttgttca gactatcttg acatatcagg
     6361 cgaattcaac gccagcttgg gtatcgatga ggtttggagc aatgcaagct ataccagaaa
     6421 ttggtacgga gtcatctacc gccatttgat ggaatattca gaaaccggtt cagaagtcag
     6481 tgccttcaag aatccttggt caaacctctg cggtgaaatc gcttcagaaa aagctagttc
     6541 acgcgatgtc atgatggcag gcttcacggc cgccagtgga aactatcatc gctgggccaa
     6601 tttctacaaa gacgtacgcc aagccatgat tttcattgag cgcgcccaag accaaggcgt
     6661 aggcgacccc accagcaccg acaagctgac tgccgaagag atagcccgca tgaaggacga
     6721 atgccgcttc atgattgcct actattactt ctccatgttc gagctttatg gccctgcctg
     6781 catcgtgacg gagatagacg acgctgccga accgcacata acggactacg accgcgctac
     6841 tgtagacgaa atggtgaacc acattgatgg catattggct cctctatgtg accccgcaca
     6901 gtcaaaattg cccgaatcag tcatcacatc atacgcggac aatacataca acttcaacac
     6961 caatgaagta gtacgcccca ctatcgtagt ggccaaagca ctacgcgcca agttgtggat
     7021 gtatgctgcc tccaagttat tcaatggtgg cgatggttcc gaatattacc agggactgca
     7081 gaagttgcag aactctaaag gtgaatacat cttcccacag agtaaggatc cgcaaaaatg
     7141 ggtaactgcc agagaccgcg taaaggatct gatagactat gctgaagcgc aacaccacgc
     7201 tctctatcgc gtgatggcaa acggagtaga gcaacccgac cgttctgtat acaacctttt
     7261 ccaggtgtac aatgaagaaa tcctgtggtg cagtaccaac aacagctact ccgaccagta
     7321 caagatggag aaacgtacta acccgcgtga cgtgaactca tgctatggta ccatcggccc
     7381 gtctcaggat gctgtagaca tgttcttcat gggcaacggc ctcgccatca atgacccaaa
     7441 cagtggttat gacgaaaccg gattcggtgc tgtagaaaac cattgttacg accccgacta
     7501 taaagacaag aagacagacc agaatatctc caacatgtat gccaaccgtg aaccgcgttt
     7561 ctacgcaagc gttgtatatc agggaagaag ctggttcaag aaatggatga acggtaatcc
     7621 caactacatc gtagatttct ctgcaggtgg cggaaacgac ctttccaacg gtgacaacgt
     7681 gaaaaccgga tatatgctgg ggaaatttaa gaaccgtacc gtaaatcatg ccagcggcga
     7741 tactcagagt tggaaacgtg tttccatcat ctatcgtctg gccgaattct atctgttcta
     7801 tgccgaagca ctcaatgaaa cagatccgag taatccggac atcatcaagt atatcgacat
     7861 ggtacgcgaa cgcgcaggca tcccaggcta tcagaccatg aacgataacg gcatcaagac
     7921 cggcataatc ggcaattacg acaagcagtt cgatgccata cagcacgaac gctatgtaga
     7981 gctctattgc gagggacaac gctatttcga catccgtcgt tggatgatct gcggtgacaa
     8041 ggacagaata ggttgcgacc agacacgttt ctacggaatg aacatgaagg gttcaaaaga
     8101 caagactccg ggcgaaccaa cttcttacta cacgcgtacg aaagtagaaa accgacaatg
     8161 gacagacaaa ctctacctct atcccatcca tcagaatgtg atagaactgg ccaacggacg
     8221 tattccacaa aattacggat ggtaaaaaag acagcttttt tgattagttt tcgaaggata
     8281 taagtaaaaa gattgaatga aggtttggag gcagaaactg gcataaccgg cctggtaact
     8341 gcctcctttc tttttcagct aataaaccaa caataaatat accatgagaa aagagaaaaa
     8401 atatcgaatc gggacatacc tgatcctgat acctgctatt ctgttcctat tccccaaagt
     8461 atacgcacaa catgagagca aaacgatcaa cgacagttgg aaattctatc agggagaatg
     8521 caaagctgcc gcttcagcaa cctatgatga cagtgcgtgg aacagcatac atctcccgca
     8581 cacatggaat acggatgcat atacagaaaa aaagtattac cagggaacag gctggtatcg
     8641 ccgtacgctg acattaccgc aaaattggca aaccaaacag gtattcctga aactggatgc
     8701 agccagtaag gccgctacca tctacatgaa tggacggaaa ataggtgagc ataacggtgg
     8761 atatactgcc tgcacattcg atatcacccc attctgttca tttgacgctc ctaattctct
     8821 cgctatccat gtagataatg cccgacagga tattcccccc atctctgccg actttacatt
     8881 cttcggcggt atctaccggg atgtatggct tacagccgta cccaaacaac atttccattt
     8941 gacgaactat ggttcagaag gaatatttat cagtaccccg caagtatccg aagaaaaagg
     9001 cacaatactt attcgcggag agataaagaa cgatgcagaa cagaaagcat ctcttgaact
     9061 ggaacatatc atctacaatc ccgatggaag tattgcccag acccagaaac agtctatcca
     9121 gataaaaggt ggagaattat actctttccg caccgaaacc tcccctattc tatccccccg
     9181 attatgggca cccgaggctc ctcatctcta cagagtagaa agcattctgc gcgataaaaa
     9241 aacaaaagcc atcctcgacc acagtaatca ccatacaggc ttccgctggt ttagcttcga
     9301 tggtaagacc ggcttctccc tcaacggaaa accttataaa ttacgcggta tttgccgcca
     9361 tcaggaccaa aaacccatcg gagttgccct gacagacgaa atgcaccgtc gtgacatgaa
     9421 gttaatgaaa gagatgggcg ccaacttcat ccgcatctcc cattatccgc aagatgacgc
     9481 tctgttggaa atgtgcgaca aactcggtat gctagcttgg gaagaaatac ccattattga
     9541 tattgtgccc gacactcccg gctatgcaga aaactgcgaa aacaatctgc gagaaatgat
     9601 acgccagcac tataaccacc cctccatcat cacctgggga tacatgaatg agatattact
     9661 cgtcacccag cgccgctata aaaaagaaga agaactgaaa cccgtgctgg aacggacact
     9721 gtcactggcc aatcgtttgg agaaagttct gaaagaagaa gattccactc gtgtcagcac
     9781 tatggctttt catggcagca acagctataa tgaggtagga ctgggcaaca tcaccgatat
     9841 tgtcggctgg aatctttacc aaggctggta tggaggagat ctcacaggct tcgaacgttt
     9901 cctgacagag caacacaaaa aacacccttc tcatccgatg attgtcagcg aatacggtgc
     9961 cggatctgac aagcgtctac attcgctgca accgcacgct tttgatttca gtatcgagta
    10021 ccaacagaaa tacctggaac actacttacc gatattggaa gaaacgccgt atatttgtgg
    10081 tggaactcac tggaacttta tcgatttctc ttctgcattg cgtgatgaat ctatgccgcg
    10141 catcaacaat aaaggactgg tatactcaga ccgcagtcca aaagacgtgt actattacta
    10201 taaagccgcc tggcgtcaaa acattcccgt gttacacatt gccagccgtg actggacgca
    10261 ccgtagcggt gtacaacatg gaaaggctcc ggttccgcta cccgtcaagg tatataccaa
    10321 tcttccggaa gtggaactct tcattgacgg aaaatcctta ggcaaacaga aaacagagaa
    10381 ttatacagtt acatttcagg taccattcag ccggaaaaag cacttcatct tcgcccaagc
    10441 tgaaaacaaa gagtcagatc aaagcatctc catgatagaa gatgccctcc acatcaactt
    10501 cacccctatc cctgcaaatc tgaatgaaac aaacttacgg aatctggaac ttgccgtaaa
    10561 tgtaggcagc aactgtttct atacttccga tgaaagccag ctcacgtggc tacccgatca
    10621 accctacact gaaagcagtt ggggatatat cggcggagaa agcagaaata gccagacaca
    10681 ggttgagaat acccacgacg gaccattgtt tcaaactctt cgcaacgaaa ttgaagggta
    10741 ttgtttcgat gttcccaacg gagtctacga ggtagaattt ctttttacag atatcttccg
    10801 cgaaaatgca gcaactgttt accagttggg ccgggaatcc ggtgtagaga gccgtgaaaa
    10861 tatcttcgat atagttatca atggtgagag cgttgaagag aacttttctc cttgccgcga
    10921 aagcggttat ttccatactc tacggaaaag atacaatatt acaaactttc ggaataaaat
    10981 tgaaatacgc ttccctgttc ggaatggaaa aagctttctg aacggtataa agctcaggaa
    11041 actttattaa cttcaaaaca aaaacaccat gagagctaaa atttgcttag ttattaccag
    11101 tttgttgctc gcagtagtca gtatacatgc acagtccatc tgggatggga aacatctgga
    11161 gagagtaaaa caatcattac atcaaccgta cttttcggcc gcctatcagg agctgatttc
    11221 aggtgccgac aggctactgg atgtgcgccc cttgtccgtc atgctgaaag agaagacacc
    11281 cggtagcgga gacaagcacg actacatgag tcaggcacgc tattattggc ccgatccctc
    11341 caaacccgat ggcctgcctt acatcagcca tgacggcaag tcgaaccccg aactggacaa
    11401 gctggatcgc aaccgcctcg gagaaacagc tcagcgtgta actactcttg cccttgcctg
    11461 gtactttagc ggcgacgaga aatatgccca aaaggcaacg gaacttatcc gcgtatggtt
    11521 ctttaataaa gatacgcgta tgaatccaaa cctggagtat gcccagatga taccgggaca
    11581 caacaacaat aagggacgtt gttacggcgt catagacact tattcattcg tagagatgct
    11641 ggatgccgta cagttgttag agaagtcgga agcctttacg cccaaggatg ccaagcagct
    11701 gaaaacctgg ttcggcaagt tgctgacgtg gatactgaat agtccgcagg gacaggaaga
    11761 agcccgtcag gccaataacc atagcacggc gcatgatgca caagtgatag cctttgccat
    11821 gtacgcagga aacatgaaag tagcccggga agtcatcaat gccattcccc ggaagcgcct
    11881 cttcacccag atagagccgg acggcaaaca accgcatgaa ctacgccgca ctctcgcttt
    11941 cggttactca caattcaatc tgtctcattt cattgacatc ttcatgatgg cccggaagat
    12001 cgggatttcc attgataatg caacctccga agacggacga agcttctaca aagccatgga
    12061 ctttctggta ccatacgttg gaaaagatgt caaagcctgg ccgtaccagc agatcagtga
    12121 atggaaatac aagcaacagg aattctgcaa agacctgtac cgcactttcc tgctgaaccc
    12181 cgaacgcaaa gattatctga agctctataa aacccatcgc atcatcgact ggaaagaccg
    12241 tttcaacctg ttatggatgg aagccgatga tgtggacaat gcctacgcct ttgcctgcgg
    12301 acaactgcaa tttgccatgc agtgtgctgc caaggcccga aaagaggcag acaatcaatg
    12361 caagcatcgt gtaattcccc gtagcatcaa caaagacggt tcgctgcgga tgatacatcc
    12421 tcacgattgg tgctcaggct tctttcccgg ttcattatgg caggtatacg cctatacaaa
    12481 cgatgatttc tggcggcagc aggccatcag caatacttgg ctgatagaag aagccaaatg
    12541 gcataaaggc actcacgacc tcggtttcat gatgaacaac agtttcggca aagcctatca
    12601 gttgacaggc gaacgctctt acaaagatgt ggtgctgcaa agcgccaaaa ccctgattac
    12661 ccgctacaat aagaaagtaa agagcatccg ttcgtgggat cataatcgcg ataaatggaa
    12721 gtttccggta atcatcgaca acctgatgaa cctggaaatg ctattctggg ctacacagga
    12781 aaccggagat tccatctact ggaaggttgc cgtaaatcat gccaatacaa ctatgaagaa
    12841 tcatttccgc ccggactact cttctttcca cgtagtagat tacgatccgg aaaccggcga
    12901 agtacgcgcc agacaaaccg cacaaggcta tgccgacgat tccttctgga gccgcggaca
    12961 ggcatgggca ctatacggat ataccatgtg ctaccgcttc accaagaacc ccgcatacct
    13021 gcaacaggca cgccacattg cagatttctt tttcggtctg cccaacctgc cggaagacat
    13081 ggttccctac tgggacatga aagctcccgg catccccgac attccccgcg acgcctcggc
    13141 tgcagccatc atggcttccg ccctgtatga actccgcact tacgtttcag cagaagatgg
    13201 caaccgttac caaaacattg ccgacaagat agtggacagc ctcaaccagc actatcaggc
    13261 cgagccggga acaacttatg gcttcctgct cctccattcc accggacacc atccgggagg
    13321 tgatgaaatt gatgtgccca tcaactatgc cgactattat tatctggaag cattggcaag
    13381 aaaagaggct cttaagcaat aa
//
