LOCUS       CP012801               13750 bp    DNA     linear   BCT 16-OCT-2015
DEFINITION  Bacteroides cellulosilyticus strain WH2, complete genome.
ACCESSION   CP012801
VERSION     CP012801.1
DBLINK      BioProject: PRJNA289334
            BioSample: SAMN03852682
KEYWORDS    .
SOURCE      Bacteroides cellulosilyticus
  ORGANISM  Bacteroides cellulosilyticus
            Bacteria; Bacteroidetes; Bacteroidia; Bacteroidales; Bacteroidaceae;
            Bacteroides.
REFERENCE   1  (bases 1 to 13750)
  AUTHORS   Wu,M., McNulty,N.P., Rodionov,D.A., Khoroshkin,M.S., Griffin,N.W.,
            Cheng,J., Latreille,P., Kerstetter,R.A., Terrapon,N., Henrissat,B.,
            Osterman,A.L. and Gordon,J.I.
  TITLE     Genetic determinants of in vivo fitness and diet responsiveness in
            multiple human gut Bacteroides
  JOURNAL   Science 350 (6256), AAC5992 (2015)
   PUBMED   26430127
REFERENCE   2  (bases 1 to 13750)
  AUTHORS   McNulty,N.P.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-SEP-2015) Center for Genome Sciences and Systems
            Biology, Washington University School of Medicine, 4444 Forest Park
            Ave., Saint Louis, MO 63108, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method       :: HGAP 2.0 and Celera v. AUG-2014
            Assembly Name         :: B_cell_WH2_2.0
            Long Assembly Name    :: Bacteroides cellulosilyticus WH2 2.0
            Genome Coverage       :: 209x
            Sequencing Technology :: PacBio; Illumina MiSeq
            ##Genome-Assembly-Data-END##
FEATURES             Location/Qualifiers
     source          1..13750
                     /organism="Bacteroides cellulosilyticus"
                     /mol_type="genomic DNA"
                     /strain="WH2"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:246787"
     gene            1..4080
                     /gene="todS_12"
                     /locus_tag="BcellWH2_02517"
     CDS             1..4080
                     /gene="todS_12"
                     /locus_tag="BcellWH2_02517"
                     /EC_number="2.7.13.3"
                     /inference="ab initio prediction:Prodigal:2.6"
                     /inference="similar to AA sequence:UniProtKB:E0X9C7"
                     /codon_start=1
                     /transl_table=11
                     /product="DBD-Pfam|HTH_AraC,DBD-SUPERFAMILY|0035607"
                     /protein_id="ALJ59756.1"
                     /translation="MQKFIRTLFLVLVSIVTANVHSQNITFNHLTTDDGLSQFSVNSLY
                     IDENGILWIATREGLNRYNGNDIQTYKLNKNDPYSLFCNTVLRMAGDQNGKIYLLCTEG
                     VAQFDLTTQRFTTLLQGNINSIYYKNGLFIGKKNEIYRYNEQTDNFDLYYQMAGENIEI
                     SCMFEDKGHMWIGTTSEGVFNLKIDEHLLTHPIEKGNITSIYQDNAGELWIGSWEKGLF
                     RVKTDGNIENLRNDPKNPHSISSDFVRSCCEDNLGNIWIGTFNGLNRYNKTTGLFQNHT
                     SNEMQNEGLTHSSIWCIVKDNQGTLWLGTYFGGVNYFNPEYEIYTRYKASIHEKEGLSS
                     PVVGRTIEDKNGNLWIGTEGGGLNFYNRRTREFKWYLAGQGRNSISHSNVKALYYDPAK
                     EIIWIGTHLGGLNKLDIRTGTFTHYLMEEGNPETLPSNIVRDIAPYQDQLIVATQNGVC
                     LFNPQTGKCQQLFKDSKEGRKIAMVADVEVDNSGTLWIAATGEGIFSYRFDTNKLTNYR
                     HDGTQAHSLSNNNVNNIMQDSKGNLWFSTSGSGLDLYRSATNDFENFDKGKNGLVSDCI
                     YDTQESPVSGKLILITNQGFSIFDQKVEKFQNYSVENGFPLTAVNENALCVTRDGEIFL
                     GGTQGMLSFNELELNFTPKPYKIILSRLIVNGAEVKVSDETGILTQSLCHTQEITLNAN
                     QTMFSIEFATSNYVAANKNEIIYKLEGFSEDWNSTRGQPIITYTNLNAGTYNLLIKPKG
                     KEESICPQVHLTIHVLPPYYKTPLAYLIYLIVTGILLWYLVKTYKSRIKLRESLKYEQK
                     HIQDVEALNQSKLRFFTNISHEFRTPLTLIVSQVETLMQLQNFTPTIYNKILSIYQNSI
                     QLRELITELLDFRKQEQGHMKVKVSPHNIVHFLYENYLIFMEYASSKQINFNFEKDCES
                     LEVWYDQKQMQKVVNNLLSNAIKHTQAEDTITLSITTEGNEAVIRVTDTGSGIDAKEVD
                     KIFDRFYQTEQMDSLTTGVGTGIGLALTKGIVELHHGTIKVESELGKGSSFIVRLHLGN
                     AHFNTEEISKKSEDVQQIEQPQISEIDASLKAELEENAPIKRMPDVKMVIVEDNASICE
                     MLANIFRPFYQVLTAADGEEGLELIQKEMPNIVVSDVVMPKMSGTELCKQIKNDFNTCH
                     IPVVLLTARTAVEQNIEGLRIGADDYITKPFNTNLLISRCNNLVNSRILLQEKFSKQPQ
                     AYAQMLATNPIDKEILDRAISIIEKNLDNTEFNVNIFAREMAMARTNLFTKLKAITGQT
                     PNDFILTIRLKKGALMLRNNPELNITEISDKIGFSSSRYFSKCFKDVYQISPLAYRKGE
                     NMDSDEKNEEEPPLAT"
     gene            4226..5785
                     /gene="atsA_10"
                     /locus_tag="BcellWH2_02518"
     CDS             4226..5785
                     /gene="atsA_10"
                     /locus_tag="BcellWH2_02518"
                     /EC_number="3.1.6.1"
                     /inference="ab initio prediction:Prodigal:2.6"
                     /inference="similar to AA sequence:UniProtKB:Q9X759"
                     /codon_start=1
                     /transl_table=11
                     /product="Arylsulfatase precursor"
                     /protein_id="ALJ59757.1"
                     /translation="MKHFSPLWSLLPGAALIAGCGNPSKKETTDNTRQKPNVIYLIADD
                     LGIGDLSCYGATKISTPNIDRLAGQGVQFTNAYATSSTSTPSRFGLLTGMYPWRQENTG
                     IAPGNSELIIDTACVTMADMFKAEGYATGAVGKWHLGLGPKGGTDFNHLIKPNTQDIGF
                     DYEYIIPATVDRVPCVFVENGHVVGLDPNDPITVNYNHKVGDWPTGLENPELVKLKPSQ
                     GHNNTIVNGIPRIGWMTGGKSALWVDEDIADVITGKAKDFIIKHKDEPFFMYMGTQDVH
                     VPRVPHARFAGKSGMGTRGDVILQLDWTVGEIMNTLDSLNLADNTIFVFCSDNGPVIDD
                     GYQDQALELLNGHTPMKQYRGGKYSAYEAGTRIPFIVRWPAGIQPCKQQALFSMIDVYA
                     SLAALLNHPLTPATVAPDSRDQLATFLGKDNTGCDYVVQQNLNNTLSIIQGTWKYIEPS
                     DKPAVEHWTKMELGNDPKPQLYNISIDPSEKNNVAAAHPEMVKELSTLLEQVKAGKNQG
                     TK"
     gene            5955..9095
                     /locus_tag="BcellWH2_02519"
     CDS             5955..9095
                     /locus_tag="BcellWH2_02519"
                     /inference="ab initio prediction:Prodigal:2.6"
                     /inference="protein motif:Pfam:PF00593.18"
                     /codon_start=1
                     /transl_table=11
                     /product="gnl|TC-DB|Q45780|1.B.14.6.1"
                     /protein_id="ALJ59758.1"
                     /translation="MKQKVTLILLATFLCCVLGVQAQTGSQVTGKVVDAMGELPGVSVV
                     VKGTTNGTTTDVNGEFKLGNVKNSDVLQFSFIGYKTLDVKVGNQRKFDVTLQEDAQALD
                     EVVVVAVGYGDVRRRDLTGSIGSANMSDLVKAPVTNIAESLGGRIAGVQVSSSDGGLGD
                     NFNIVIRGAGSLTGSTAPLYVVDGFPQETSTMSALNQNDIESIDILKDASATAIYGARG
                     ANGVVIITTKKGGAGKPTITYNGSMTVGQVKNTADMMNAYEFVQLQRELLDDADFESNY
                     ITDLYGSLEDYRYAPTYDWQDYIYRTALSHNHHVSMTGSQGDLKYSTSLSYTDQQGIII
                     RSGLKRYQGRVNLSQKVNKRLKVDFTGNYASNVQDGPTASTATTAMSTAYMYSVWAFRP
                     VSPTGSDMLNQMYDEGVNMTEDYRFNPVHSARNEYRHKTTNNLQFNVSADYEFIKGLKL
                     KIAAGYTSRDYTNEEFNSSMTRTGNSHPSNTQSKGINAYLYKSEARSYLNENTLTYQFN
                     KNKHNFNALAGLSFQKNTSYIYSITAEHIAKDSYGMAGLDKGSSTPSVTSSKGENTLMS
                     YFGRINYNYDSRYYVTATMRADGSSKFAKNNRWGYFPSGSLAWAFQREAFMSDVNWLSN
                     GKLRFSYGQTGNNRIGNYEYMAHLVTSDDVYKYPWNGQFNQGYVLSSMENEKLKWETTE
                     QLDFGIDLGFLNGRINLTMDYYIKTTKDLLLDANIAASSGFATATLNVGKLRNNGFELT
                     LETTNVKTKDFNWTSNFNIAFNKNKIISLNSGQEDITSYITWDNKYRTTPAYISKKGEA
                     AGKMYGFIYEGTYKYEDFNITEENGKKVYTLKEGIPYYVANTQPGDPKYKDLDNSGTIT
                     DKDKTTIGNGQPKHIGGFSNNFTYKNWDLNIFLQWSYGNDILNANRLVFENPGGKKNTN
                     MFAGYVNRWTEDNPTSNIPRAKANGAAEYSSLYVEDGSFLKLKTISLGYNFLPKTLRPL
                     HISSARLYVSAENIATITGYSGNDPEVSTRNSILTPGFDWSPYPRSFNMSVGLNVTF"
     gene            9113..10717
                     /locus_tag="BcellWH2_02520"
     CDS             9113..10717
                     /locus_tag="BcellWH2_02520"
                     /inference="ab initio prediction:Prodigal:2.6"
                     /inference="protein motif:Pfam:PF07980.5"
                     /codon_start=1
                     /transl_table=11
                     /product="gnl|TC-DB|C6Y217|8.A.46.1.3"
                     /protein_id="ALJ59759.1"
                     /translation="MKTIYKSLRNISLALCATMAISSCDSFLDTKPYDFVAPQTFYTNE
                     SECTMALAGVYYTLVYEQTYGNYYSCMISNVDDLSYYQRPEGQTASYVYGNDHSPSEQY
                     IWGAWETLYKGINNANMLIENVDGADMEDAIKTRIKGEAKFLRAYYHFLLVQGWYEVPL
                     RPESFKDVNNSSKEATSHVEALDWIIQEMEDCVDMVDNTNYDLSPSYVKKNSVMGVLAR
                     VYLWRACYPFDGKISSDGKAYFEKAAYWATQVKNSNKHHLNPDVYTMWKAMASDTYDTE
                     YNESIWEAEFIGTRDDGSYTAGRIGNVIGNIQKGTANPGNGYAYGFYAPTLILWDLFDE
                     KDKRRDLSIAPYQINAKEEKVEWTAKQIVQRSCGKFRREWESAATKHKNYTPENYPLLR
                     YADVLLMLAEAENEANQGPTTSAYEAINEVRERAGIDPLKNLSYSDFQQAVRDERAREL
                     CFESLRKYDLVRWGIYEKAIHDDLGAATKDSRWATGTNFIGAATYAQRTSEKHQFLPIP
                     TKELGVNTKLKQNKYWE"
     gene            10847..13750
                     /locus_tag="BcellWH2_02521"
     CDS             10847..13750
                     /locus_tag="BcellWH2_02521"
                     /EC_number="4.2.2.20"
                     /inference="ab initio prediction:Prodigal:2.6"
                     /inference="similar to AA sequence:UniProtKB:P59807"
                     /codon_start=1
                     /transl_table=11
                     /product="PL8_2"
                     /protein_id="ALJ59760.1"
                     /translation="MTRKHLLFILALLCGQVSFAQLIGFETGIPKQFQTSDKGKITLST
                     QYYKEGKQSLKWDFRSGSKLSVALEQPLTLDKRMENSYGITLWIYNEAPQQDSIRFEFL
                     SPQGDVSYWFSFQLASAGWRACWIGFQHMKGNKQNKEIASYRLIAPERKGRIFLDRLTF
                     PVKKMNDRTTPDLQMPYNNSLSYRDLWHWCRVWQWEQYKYDIPLPSTLNQAEKDELRTV
                     EQRLTTALDIQKAPKEAVSKAYDVFQKANIQRSGTGFTGTPILTPDELDRSKGEISWND
                     LETMLSGFAYDTYYNHSETSRQNYFTVWDFAIDQGFSFGSGMGTNHHYGYQVRKIYTTA
                     WLMRNAIWKAPNRDNILSTLIFWSALQETRQPYQYGRDELLDSWHTLLMAKTVSALLFT
                     DERERVRALKGLSRWVSSSLQYTPGTIGGIKVDGTTFHHGGFYPAYTTGVLATVGQFIS
                     LTNNTVYEPTEEARQVLKSAFIAMRNYSNKYEWGIGISGRHPFGGSMKADDVAAFAYLA
                     LSGDLSGEGNAFDHHLAADYLRLCEKDTPEARYFKAQGITPAPAPQGFFVYNYGAAGIF
                     RRNDWMVTLKGYTTDVWGSEIYRKDNRYGRYQSYGSVQIMGYPSRLASGYDENGWDWNR
                     LPGTTTIHLPFELLDSPLPGTTMAHSRENFSGSSSLENRNGMFVTKLMERELKNFTPDF
                     VARKSVFCFGNRMICLGSGIKNSNNSYSTETTLFQSIFHKGINSIQINGDEHKEVGFYQ
                     KINCKAEQPACIKDSYNNYYFVKDGKIKVQIAEQKSLHEKTRAVTQGTFASSWIDHGKA
                     PNNATYEYMIWIQPTSEELKKQALQSYEVLQRNNDAHIVHDYVTGITAYALFESFESQT
                     DKLFHSIPAETMVMYRNDNDKIILSVCDPNLNISEKTYTTKEPSRIIKKQLELKGLWKP
                     TKNSKQTEISYKANSTSLTVYCQHGQPVEITLINLPQ"
ORIGIN
        1 gtgcaaaagt ttatcagaac gctgtttctt gttttagtaa gcatagttac agcaaacgta
       61 cacagccaga atatcacttt caatcattta accaccgacg acggcctatc tcagtttagt
      121 gtcaacagtt tgtatattga tgaaaatggt atcttatgga ttgctacgcg cgaaggtttg
      181 aaccgttaca atggaaacga tatacagact tacaaactga acaaaaacga tccctacagc
      241 cttttctgta acaccgtgct ccgtatggca ggcgaccaga acggaaaaat ctacctgctc
      301 tgtaccgaag gtgttgccca gttcgacctg actacccaac gcttcaccac cctcctgcaa
      361 ggaaacatca atagcatata ttataaaaac ggccttttca tcgggaaaaa gaatgaaata
      421 taccgctata atgagcaaac cgataacttt gatctttact accagatggc aggagaaaac
      481 atcgaaatat cctgcatgtt cgaagacaaa ggacacatgt ggataggaac caccagcgaa
      541 ggtgtgttca atctgaaaat agacgaacat ctgctaactc accccatcga gaaaggaaat
      601 atcaccagta tttaccagga caatgcaggc gaactgtgga tcggaagctg ggaaaaggga
      661 ctcttccgag tgaaaacaga cggaaatatc gagaacctgc gaaacgaccc aaagaacccg
      721 catagcatat cttccgattt tgtcagatcc tgctgcgagg ataatcttgg caatatctgg
      781 atagggacct tcaacggcct gaaccggtac aataaaacga caggactttt ccagaaccat
      841 acctccaacg agatgcagaa tgaaggactt acacactcgt ccatctggtg catcgtaaaa
      901 gataatcaag gtactttatg gctgggtact tacttcggcg gtgtcaatta cttcaaccct
      961 gaatatgaaa tctatacccg atacaaagct tccattcatg aaaaagaagg attaagcagt
     1021 cccgtagtcg gacgcaccat tgaagataag aatggaaatt tgtggattgg cacggaagga
     1081 ggcggactga acttctacaa ccgccggaca cgtgagttca agtggtatct tgccggacaa
     1141 ggacgcaaca gcatctccca cagtaacgtg aaagcccttt attatgatcc cgcaaaggaa
     1201 atcatctgga taggaaccca ccttggcgga ctgaacaaac tggatatccg cacaggtaca
     1261 ttcacgcatt atcttatgga agaaggaaat ccggaaactc ttccgtccaa tatcgttcgt
     1321 gacattgccc cctaccagga ccaactgatt gtcgctaccc aaaacggtgt atgcctgttc
     1381 aatcctcaga ccggaaaatg tcaacagctc tttaaagata gcaaagaagg gcgtaaaata
     1441 gctatggttg cagatgtaga ggtagataat agcggtacac tctggattgc cgccacaggc
     1501 gaaggtatct tctcctaccg cttcgatacg aacaagttga ccaactaccg tcacgacgga
     1561 acgcaggcac acagcctcag caacaataat gtgaacaaca tcatgcagga cagtaagggt
     1621 aacttgtggt tctctacttc gggaagtggc ctcgacctgt accgttccgc taccaacgat
     1681 ttcgaaaact tcgacaaggg caagaacgga cttgtcagtg attgcattta cgatacacaa
     1741 gaatctcccg tcagcggtaa actgatactg attaccaatc agggcttctc catcttcgat
     1801 cagaaagtgg aaaagtttca gaactacagc gtggagaatg gtttcccact gacagctgtc
     1861 aatgaaaacg ccctttgtgt gacacgcgac ggagaaatct tccttggcgg tacgcaaggt
     1921 atgctctcat tcaatgaact ggaacttaat ttcaccccga agccttacaa gatcatcctt
     1981 tcccgcctca tcgtaaacgg cgccgaagta aaagtgagcg atgaaacggg tattttgacg
     2041 caatccctat gccatacaca ggaaatcacc ctgaatgcta accaaaccat gttcagcatc
     2101 gaattcgcca cctccaacta cgtggcagcc aataagaatg aaatcattta caagctggaa
     2161 ggcttctccg aagactggaa cagcacgcgc ggccaaccta tcatcaccta cacgaacctg
     2221 aatgccggaa catacaatct gctgattaaa cctaaaggaa aagaagagtc catctgtccg
     2281 caggtgcatc ttacgattca tgtactgcca ccttattata agactccgct cgcctatctt
     2341 atttatctga tagtgaccgg tatccttttg tggtatctgg tgaagacata caaatcgaga
     2401 attaagctgc gtgaatcgtt gaagtacgaa cagaagcata tacaagacgt ggaagcgctg
     2461 aaccaatcga aactacgctt cttcaccaac atctcacacg agttccgcac gccgcttaca
     2521 ctcatcgtat cgcaggtgga aactctgatg caattgcaaa acttcacacc caccatttat
     2581 aataagatac tgagcattta ccaaaacagc atccaactgc gcgaactgat caccgaactc
     2641 ctagacttcc gcaaacagga acaaggacac atgaaggtaa aagtcagtcc gcacaacata
     2701 gtgcatttcc tttatgagaa ttacctcatc ttcatggaat atgcaagcag caaacagatc
     2761 aatttcaatt ttgagaaaga ctgtgaaagt cttgaagtat ggtatgacca gaagcaaatg
     2821 cagaaggtag tcaataacct gctatccaat gccatcaagc atacccaagc cgaagatacc
     2881 atcacactca gcatcaccac cgaaggcaat gaagccgtaa ttcgcgtgac tgatactggt
     2941 agcggtatcg atgccaaaga agtagataag atattcgacc gtttctatca gacagagcag
     3001 atggacagtc tcaccaccgg tgtaggcacc ggcatcggtc tggccctgac gaaaggcatc
     3061 gtcgaactgc accacggtac catcaaggta gaaagcgaac tgggcaaggg cagcagtttc
     3121 atcgtccgcc ttcacctggg caacgcccat ttcaatactg aggaaatcag caaaaagagc
     3181 gaagacgtac agcaaataga acaaccgcaa atttctgaaa tagatgcttc actcaaagct
     3241 gaattggaag aaaatgcccc gattaagcgc atgcccgatg tcaagatggt tatcgtggaa
     3301 gacaatgctt ccatttgtga gatgttggca aacatcttcc gcccattcta tcaggtgctg
     3361 acagccgcag acggtgaaga aggtctggag ctgatacaga aggaaatgcc gaatattgtg
     3421 gtaagcgacg tcgttatgcc caaaatgtcc ggtaccgagc tctgcaaaca gattaaaaat
     3481 gatttcaata cttgccacat accggtagta ctgcttaccg cacggactgc cgtagaacaa
     3541 aacattgaag gactgcgtat cggtgcggac gattacatca ccaaaccatt caacacgaat
     3601 ctgttgattt cgcgttgtaa caacctggta aattcacgca ttctcctcca agaaaagttc
     3661 agtaaacaac cacaagctta tgcacagatg cttgccacca acccgataga taaggaaatc
     3721 ctggaccgcg ccatcagcat catcgaaaag aatctggata atacggaatt taatgtcaat
     3781 atcttcgccc gcgaaatggc tatggcacgt accaacctgt tcactaaact gaaagccatc
     3841 accggacaaa caccgaatga cttcatcctg accatccgcc tgaaaaaagg cgccttgatg
     3901 ttgcggaaca acccggaact aaacattacc gagatatcgg acaaaatagg tttcagttct
     3961 tcacgctact tctcaaagtg tttcaaggac gtataccaga tcagtccgct ggcataccgt
     4021 aaaggagaaa atatggactc cgatgaaaag aacgaagaag aaccgcctct tgccacttaa
     4081 caggcaagag gccggcaaag taccaaacat acactcgata cgtgttttgt acgtttttcc
     4141 ccttcacttg tactctacta tacacagaat ttcccgaaag ccattacctt tgacctcaga
     4201 aataacaatc taaagtcaaa gagctatgaa acatttttca cctttatggt ctctcctccc
     4261 gggcgcagcc ctgatagctg gatgtggaaa tccatcgaaa aaggaaacca ctgacaacac
     4321 ccgtcagaaa cctaatgtga tatacttaat tgccgacgat ttgggtatcg gcgatttgag
     4381 ttgctatggc gctaccaaga taagtactcc taatatcgac cgtcttgccg gacaaggtgt
     4441 acagtttacc aatgcctatg ctacttcctc taccagtact ccttcccgct tcggtctgtt
     4501 gacaggtatg tatccttgga ggcaggaaaa cacgggaatc gctccgggta actctgagct
     4561 gattatcgac acagcctgtg tcaccatggc tgatatgttc aaagcagaag gctatgctac
     4621 cggcgccgta ggaaaatggc atctaggact cggccccaaa ggtggtacgg acttcaatca
     4681 tctgataaag cctaatactc aagatatagg atttgattac gaatacatca ttcccgccac
     4741 agttgaccgt gtaccttgtg tattcgttga gaacgggcat gtagtaggtt tggatcctaa
     4801 cgatcccatt accgtcaact ataaccacaa agtgggtgac tggcctaccg gattggagaa
     4861 tccggaactt gtaaaactga aacccagtca gggacataac aatacgattg taaatggtat
     4921 tccccgtatc ggttggatga ccggtggtaa atctgctctt tgggtggatg aggacattgc
     4981 agatgtcatc acaggtaaag caaaagattt tattatcaag cataaagacg aacctttctt
     5041 tatgtacatg ggtacgcaag atgtacatgt tccacgcgtc ccccacgccc gtttcgccgg
     5101 aaagagcggt atgggaaccc gtggtgatgt aatcctgcaa ctggactgga ctgtgggcga
     5161 gattatgaac actctggaca gtctgaacct tgcggataac accatctttg tattctgtag
     5221 cgataacggc cctgtcattg acgacggcta tcaagatcag gctcttgaac tactgaacgg
     5281 tcacactcct atgaaacaat accgtggtgg aaagtacagt gcctatgaag ccggaacacg
     5341 tattccattc attgtacgtt ggcctgccgg tattcagcct tgtaaacagc aagctttatt
     5401 ctctatgatt gatgtatatg cttctttggc tgcgttgttg aatcacccgc ttacacccgc
     5461 aaccgttgcg cctgacagcc gtgatcaatt agccactttc ttagggaaag ataataccgg
     5521 atgcgactat gtagtacagc agaatttgaa caatacttta tcgattattc aaggaacatg
     5581 gaagtacatc gagccaagtg ataaacccgc tgtcgaacat tggactaaaa tggagttagg
     5641 gaatgatccc aaacctcaac tgtacaatat ttccatagat ccgtcggaga aaaataacgt
     5701 tgcagcagca catccggaga tggtaaaaga gctttcaaca ctactggagc aggtaaaggc
     5761 cggaaagaac cagggtacaa agtaaggaat cgtacagaac agggtttctt tatcaagaat
     5821 gtacaaattc gtactttttg cgaactatta actaaagtcg acttctattc aatcacatac
     5881 atttgcgttg tgattcgagt cgtttaacga gaaagaacaa cctttttttt aaaaaactaa
     5941 ttaatttaat atttatgaaa cagaaagtaa ccttaatact attggcaact tttctttgct
     6001 gcgtattagg cgtacaggca cagacaggaa gtcaagttac aggtaaagtt gttgatgcta
     6061 tgggagaact tcccggagtc agcgtcgttg tgaaaggaac tactaatgga actactaccg
     6121 acgtaaatgg tgagtttaag ttaggtaacg taaagaactc tgatgtctta caattttctt
     6181 ttatcggata taaaacttta gatgtaaaag tcggaaatca aagaaaattc gatgttacat
     6241 tacaggaaga tgctcaagca ttggatgaag ttgttgttgt agctgttgga tatggtgacg
     6301 ttagaagacg cgacttgaca ggttctattg gatcggctaa tatgagcgat ctagttaaag
     6361 ctcctgtcac caacattgcc gaaagtttag gtggtcgtat tgcaggtgta caagtttcat
     6421 cctctgatgg tggtttaggt gacaatttca acattgttat tcgtggagcc ggctcattaa
     6481 caggaagtac cgcacctctt tatgtagttg acggattccc tcaagaaaca tctaccatga
     6541 gtgcacttaa ccaaaacgac atcgaatcta ttgatatttt aaaagatgca tctgcaactg
     6601 ctatctatgg tgcacgcggt gccaatggtg ttgttattat taccaccaaa aaaggtggcg
     6661 caggtaagcc tacaatcact tataatggta gcatgacagt aggtcaggtg aaaaacactg
     6721 cagatatgat gaatgcatat gagtttgttc aactgcaacg cgaacttctt gatgatgcag
     6781 attttgaaag taactatatt actgaccttt atggttctct cgaagattat agatatgctc
     6841 caacatatga ttggcaagac tatatttatc gtacagcgtt aagtcataat catcatgttt
     6901 ctatgacagg ttcacagggc gatcttaaat attctacttc attatcctat accgatcagc
     6961 aaggtatcat catcagatct ggcttaaaac gttatcaagg acgtgtaaac ctgagccaaa
     7021 aagtaaataa gagattgaaa gttgatttca caggtaacta tgccagtaat gtacaagatg
     7081 gtcctactgc ctcaaccgct acgacagcca tgtctacagc ctacatgtat agtgtatggg
     7141 catttcgtcc cgtatcacct accggatcag acatgttaaa ccagatgtat gatgaaggtg
     7201 tcaatatgac agaagactac cgttttaacc cagtacattc tgcacgtaat gaatatcgtc
     7261 acaaaaccac taacaattta caattcaatg ttagtgcgga ttacgaattc atcaaaggat
     7321 tgaaactgaa aattgctgcc ggatacactt caagagacta tacgaatgaa gaattcaaca
     7381 gttcaatgac tcgtacgggt aactcacatc cttcaaatac acaaagtaaa ggtattaatg
     7441 cttatctgta caaatcagaa gcaagaagtt atctgaacga aaatactctt acctatcagt
     7501 tcaataaaaa caagcataac tttaatgcac tggcaggtct ttctttccag aagaatacaa
     7561 gctacatcta ttccattaca gcagaacata tagctaaaga ttcctatgga atggcaggtt
     7621 tggacaaagg ttcatctact ccttctgtaa catcatcaaa gggagaaaat acattgatgt
     7681 cctacttcgg acgtatcaac tacaactatg actctcgcta ttatgtaact gccactatgc
     7741 gtgctgacgg ttcttccaaa tttgcaaaaa ataatcgctg gggttacttt ccttctggtt
     7801 cattggcctg ggcattccaa cgtgaagctt ttatgtcaga tgtaaactgg ctatcaaatg
     7861 gtaaattacg tttcagttat ggacaaacag gtaacaaccg tattggtaat tatgaatata
     7921 tggctcacct tgttaccagt gatgatgtat ataaatatcc ctggaacgga cagttcaatc
     7981 aaggatatgt actaagtagt atggaaaatg agaaattaaa atgggagaca acagaacagt
     8041 tagacttcgg tattgattta ggtttcctaa acggacgtat taatcttacg atggattatt
     8101 atatcaaaac cacaaaagat ttactacttg atgctaatat tgcagctagt tccggctttg
     8161 caacagccac cctaaatgta ggtaagttgc gcaataacgg ttttgaactt acattggaaa
     8221 caacaaacgt taaaaccaaa gattttaact ggacatccaa ctttaatatc gcgttcaata
     8281 agaacaagat tatttctctg aactcaggtc aggaagatat tactagctac attacttggg
     8341 ataataaata tcgtaccaca cctgcataca ttagcaaaaa gggtgaagca gcaggcaaaa
     8401 tgtatggttt catctatgaa ggaacttata aatatgagga tttcaatatt actgaagaaa
     8461 atggaaaaaa ggtttatact cttaaagaag gtattcctta ttacgtagcc aatactcaac
     8521 caggcgatcc gaaatacaaa gatctggata atagtggtac aattactgac aaagataaaa
     8581 cgacaatcgg taatggacag cctaaacata ttggtggttt cagcaataac ttcacctaca
     8641 aaaactggga tctgaatatc ttcctgcaat ggagctatgg caacgacatt ctgaatgcca
     8701 accgccttgt attcgaaaat cctggaggta aaaagaacac caatatgttt gcaggatacg
     8761 ttaaccgctg gactgaagac aatccaacta gtaatattcc acgtgcaaaa gcaaatggtg
     8821 ctgcagaata cagttcacta tatgtagaag atggttcatt cctgaaactg aaaacgatct
     8881 ctttaggata caatttcctg cctaagacat taagaccgct tcatatcagt agtgcacgtc
     8941 tttatgtgtc agcagaaaat atagcaacaa tcactggata ttctggtaat gaccctgaag
     9001 tgtcaactcg taattctatt ttgaccccag gattcgactg gtcaccttat ccacgttcat
     9061 tcaatatgtc tgtgggatta aatgtaacat tctaattaat aaaaaacaga atatgaaaac
     9121 aatatataaa agcttgagaa atatcagcct cgccctatgt gccacaatgg ccatcagttc
     9181 ctgcgatagc tttttagata cgaaacctta tgattttgtt gccccacaaa cgttctatac
     9241 aaacgaatcg gaatgtacaa tggctttggc cggagtttat tacacactag tttacgaaca
     9301 aacttatggt aactattact catgtatgat ttccaatgta gatgatctga gctactacca
     9361 acgccctgaa ggccaaacag ccagctacgt atatggtaat gatcatagcc ctagcgaaca
     9421 atatatctgg ggggcatggg aaactctata taaagggatt aataatgcca atatgctaat
     9481 agagaatgta gatggtgctg acatggaaga tgctataaaa acccgaatca aaggtgaagc
     9541 caaatttctt cgtgcatact accacttctt attagttcaa ggatggtacg aagttcctct
     9601 tcgtccagaa tcattcaagg acgtaaacaa ttcatccaaa gaagcaactt cgcatgttga
     9661 agctttggat tggattatcc aggaaatgga agattgcgta gatatggtag ataatacaaa
     9721 ctatgattta tctccgtcat atgttaagaa gaattcagtt atgggcgtac ttgcccgcgt
     9781 ttacttgtgg cgtgcttgtt atccatttga cggaaaaatt tccagtgatg gaaaagccta
     9841 cttcgaaaaa gcagcttact gggcaaccca agttaaaaat tcaaataagc atcacttgaa
     9901 tcctgatgtt tataccatgt ggaaagcaat ggcttcagat acttatgata cagaatataa
     9961 tgaatctatc tgggaagccg aatttatagg tacacgcgat gatggtagct acacagctgg
    10021 acgcattggc aatgtaatag gtaatatcca gaaaggtact gcaaatccag gtaatggata
    10081 tgcctacggt ttctacgccc ccacactaat actttgggat ctatttgacg aaaaagacaa
    10141 gcgtcgcgat ctctctatcg caccttacca aatcaatgcc aaagaagaaa aggtagaatg
    10201 gactgcaaag caaatcgtac aacggtcctg tggaaaattc cgtcgtgaat gggaaagtgc
    10261 tgcaacaaag cacaaaaact atacccctga gaattaccca ctattacgtt atgcagatgt
    10321 actgttaatg cttgctgaag ctgaaaacga agccaaccaa ggtcctacaa catcggccta
    10381 cgaagctatt aatgaagtac gcgaacgtgc cggaatcgat cctctgaaga atttatctta
    10441 tagcgatttt cagcaagctg tacgtgacga acgtgcccgt gaattatgtt ttgaatcttt
    10501 acgtaaatat gacttggtac gatggggaat ttacgagaaa gcgatccacg atgatttagg
    10561 tgctgctaca aaagactctc gttgggctac cggtactaat ttcatcggtg cagctaccta
    10621 cgctcaaaga acatcggaaa agcaccagtt tcttcctatc cccaccaaag aactgggtgt
    10681 gaatactaag ctaaaacaaa acaaatattg ggaataatca tttagttacg cataacttct
    10741 aaccttaaaa tgaaatcaaa tagaccttaa tcaatttgat atgtatgggg agagtgaccg
    10801 tgaggttcct ctccctcttt ttaaaaactt aaaaacaata tgccttatga ccagaaaaca
    10861 cttgctattc atccttgcgc tgctatgcgg tcaagtatct tttgcccaac tgataggttt
    10921 tgagactggg attcccaagc agtttcaaac aagtgataag ggaaagataa ctttatctac
    10981 tcagtattat aaagaaggga aacagagtct gaaatgggat ttccgttccg gttccaagct
    11041 cagcgttgct cttgaacagc ctctcaccct cgataaacgg atggaaaatt catacggaat
    11101 aaccctatgg atttataatg aagcccctca acaagattcc attcgttttg aattcctttc
    11161 cccccaagga gatgtatctt attggttcag tttccagttg gcatcggctg gttggcgcgc
    11221 ttgctggatc ggcttccagc acatgaaagg aaataaacaa aacaaagaaa tagcaagcta
    11281 tcggctgata gcccctgaac gaaaaggtcg catatttctg gaccgcttga ctttccctgt
    11341 gaaaaagatg aacgaccgca ctacccccga cttacagatg ccttacaata actccctctc
    11401 gtatcgtgac ctgtggcatt ggtgccgggt ttggcaatgg gaacaatata agtatgatat
    11461 tccattacct tccaccctca atcaagcaga aaaagacgaa ctgcgtaccg tagaacagcg
    11521 attaactact gccctcgata ttcagaaagc gccgaaggaa gctgtttcca aagcatacga
    11581 tgtttttcag aaagccaata ttcaacgctc cggaacagga tttaccggta ctccgattct
    11641 aacacccgat gagcttgacc gttctaaagg agaaatttcc tggaatgacc tagagacaat
    11701 gctctccgga ttcgcttacg atacttatta taatcattcc gaaacttccc gccagaatta
    11761 cttcaccgtc tgggacttcg ccatagatca gggattctct ttcggtagcg gaatgggaac
    11821 caatcatcat tacggatatc aggtacggaa aatctatact acagcctggt taatgcgcaa
    11881 cgctatctgg aaagctccaa atcgggataa tatcttatcc accctcattt tctggtccgc
    11941 cttacaagaa actcgccaac cctaccaata cggtagagac gagctactgg acagctggca
    12001 taccctttta atggctaaaa ctgtttcagc actactgttc actgacgaac gggaacgagt
    12061 acgcgcactg aaaggtcttt cccgttgggt atcctcttct cttcaataca ctccaggaac
    12121 tatcggaggt atcaaagtgg acggaaccac ttttcaccat ggtggtttct atccagccta
    12181 tacaacagga gtactcgcca cggtaggcca atttatttcc ttaaccaata ataccgttta
    12241 tgaacctacc gaagaggctc gtcaagtgct gaaatccgcc tttatcgcca tgcgcaacta
    12301 ctccaacaaa tatgaatggg gaattggtat cagcggacgg catcctttcg gtggctcaat
    12361 gaaagcggat gatgtagccg cttttgctta tcttgccttg tcaggagact tatcaggaga
    12421 aggcaatgcc ttcgaccacc atctggcagc agactatcta cggctttgcg aaaaggatac
    12481 ccccgaagca cgttacttca aagcacaagg cattactccc gcccccgcac cacaaggttt
    12541 ctttgtatac aactatggtg ctgcaggtat atttcggaga aacgattgga tggtaacctt
    12601 aaaaggttat accactgatg tctggggatc tgagatttat cgaaaagata accgttatgg
    12661 acgttatcaa agttatggtt ccgtccagat tatgggatac ccttcacgcc ttgcaagtgg
    12721 ctacgatgag aacggttggg attggaatcg cctgccggga actacgacca tccatttacc
    12781 ttttgaattg cttgacagtc cactaccggg aaccaccatg gctcattcta gagagaattt
    12841 ttcaggcagt agttctcttg aaaacagaaa cggcatgttt gttacaaaac tgatggaacg
    12901 cgaactgaaa aactttactc cggatttcgt agcccgtaaa tcagtcttct gttttgggaa
    12961 ccggatgata tgtttaggta gcggaattaa aaatagtaat aacagctatt ctacagaaac
    13021 gactttgttc caaagcatct tccacaaagg aataaacagt atccagatca atggggatga
    13081 acacaaagaa gtaggcttct atcaaaaaat taattgtaaa gcagagcaac ccgcctgtat
    13141 caaagacagc tataataatt attattttgt aaaggatgga aaaataaaag ttcagatagc
    13201 ggaacaaaaa tcacttcatg aaaaaacacg tgctgtcacc caaggtactt tcgcatcctc
    13261 atggattgac cacggcaaag ctccaaacaa tgcaacctac gaatatatga tatggataca
    13321 acctactagt gaagaattaa aaaagcaagc actgcaaagc tatgaagtat tgcaacgtaa
    13381 taatgatgca cacattgttc atgattatgt aaccggcatc actgcttatg cactatttga
    13441 atcattcgaa tcacaaactg ataagttatt ccatagtata cctgcagaaa caatggtaat
    13501 gtaccggaat gataatgata agattatttt aagtgtttgt gatccaaatc tgaatattag
    13561 cgaaaagact tatacaacta aagaacccag ccgtatcata aagaaacagc tggagttaaa
    13621 aggcttatgg aagccaacaa agaatagcaa acaaacagaa atctcttata aagccaatag
    13681 cacaagcctc accgtttact gccaacatgg acaacctgta gaaataacac taatcaatct
    13741 cccccaatag
//
