LOCUS       CP012801               11930 bp    DNA     linear   BCT 16-OCT-2015
DEFINITION  Bacteroides cellulosilyticus strain WH2, complete genome.
ACCESSION   CP012801
VERSION     CP012801.1
DBLINK      BioProject: PRJNA289334
            BioSample: SAMN03852682
KEYWORDS    .
SOURCE      Bacteroides cellulosilyticus
  ORGANISM  Bacteroides cellulosilyticus
            Bacteria; Bacteroidetes; Bacteroidia; Bacteroidales; Bacteroidaceae;
            Bacteroides.
REFERENCE   1  (bases 1 to 11930)
  AUTHORS   Wu,M., McNulty,N.P., Rodionov,D.A., Khoroshkin,M.S., Griffin,N.W.,
            Cheng,J., Latreille,P., Kerstetter,R.A., Terrapon,N., Henrissat,B.,
            Osterman,A.L. and Gordon,J.I.
  TITLE     Genetic determinants of in vivo fitness and diet responsiveness in
            multiple human gut Bacteroides
  JOURNAL   Science 350 (6256), AAC5992 (2015)
   PUBMED   26430127
REFERENCE   2  (bases 1 to 11930)
  AUTHORS   McNulty,N.P.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-SEP-2015) Center for Genome Sciences and Systems
            Biology, Washington University School of Medicine, 4444 Forest Park
            Ave., Saint Louis, MO 63108, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method       :: HGAP 2.0 and Celera v. AUG-2014
            Assembly Name         :: B_cell_WH2_2.0
            Long Assembly Name    :: Bacteroides cellulosilyticus WH2 2.0
            Genome Coverage       :: 209x
            Sequencing Technology :: PacBio; Illumina MiSeq
            ##Genome-Assembly-Data-END##
FEATURES             Location/Qualifiers
     source          1..11930
                     /organism="Bacteroides cellulosilyticus"
                     /mol_type="genomic DNA"
                     /strain="WH2"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:246787"
     gene            complement(1..2145)
                     /locus_tag="BcellWH2_02435"
     CDS             complement(1..2145)
                     /locus_tag="BcellWH2_02435"
                     /EC_number="3.2.1.22"
                     /inference="ab initio prediction:Prodigal:2.6"
                     /inference="similar to AA sequence:UniProtKB:Q8A6L0"
                     /codon_start=1
                     /transl_table=11
                     /product="GH97"
                     /protein_id="ALJ59674.1"
                     /translation="MKHSLFIAFFLCLGSFASAQQLTSPDGNLSLEFMEQADGVPAYRL
                     DYKGKPVLTSGRLGLLTEEADLTRGFKQTNLERASVDNYWNPVWGEYNRVRNHYNEMTV
                     TLEQPETGRILNIRFRLFNDGLGFRYELPLQRKMNYLTVKDEVTEFNLTGNHKAFCIPG
                     DYDTNEFAYTTAPLSDIAVDMEKRIAKKSYESKAEGGLTVQTPLMMKSEDGIYLNIHEA
                     ALVDYAGMLLNVDDKQFKLSAHLTPDKLGKKGYLQLPVLSPWRTVIVSDDARDILASQL
                     IYNLNEPCQYEDTSWIRPMKFVGVWWEMFTGEGKTWAYSDFYQAKPGITDYAKLKPNGH
                     HPANTAHVKEYIDFASAHGIDGILVEGWNEGWEDWASYRKDRQFLFNKAYPDFDVKELQ
                     RYAKEKGVQMVMHHETAANAADYERQLDEAFQFMVDNGYHAVKTGYVGYIIPRNEYHSS
                     QWMNNHYIHVARRAADYKVMVNSHEAVRPTGLCRTYPNWLAQESARGGEFETMGGNDPD
                     HTCILPFTRLKGGPMDYTPGIFETRLSYYNGEKPNERVHTTLVKQMALYMTMPSPIQMV
                     ADLPSNYARFPDAFRFIEDVAVDWDNSWYLEAEPGDYITVARKAKGKNEWFVGGITDEN
                     SRTATIPFSWLPEGKQYIATIYEDGKDADWDTNPQSYRIRKVVVTPKSVLKQKLAASGG
                     VAISIKEADKAEMKGLKTIR"
     gene            complement(2489..3814)
                     /gene="nplT_2"
                     /locus_tag="BcellWH2_02436"
     CDS             complement(2489..3814)
                     /gene="nplT_2"
                     /locus_tag="BcellWH2_02436"
                     /EC_number="3.2.1.135"
                     /inference="ab initio prediction:Prodigal:2.6"
                     /inference="similar to AA sequence:UniProtKB:P38940"
                     /codon_start=1
                     /transl_table=11
                     /product="GH13"
                     /protein_id="ALJ59675.1"
                     /translation="MKKYIFVVSLLCLLAACTGKRQGEAAVEIAALPAVEDVVMYQVNP
                     RVFAPEKSFKAVERRLDSIQALGINVVWFMPINEVGQEKSVNSPYCVKDYKGVNPEFGT
                     LDEFKALVATCHQKGMNVIIDWVANHTSWDNAWIANKEWYTQDEAGNIIFPAGTGWKDV
                     ADLNFDNQEMRLAMIEAMKFWVTEIGIDGFRCDAADFVPFDFWKQALDSLRAIPERSLL
                     MLAEGKRRDHFDAGFDMNYSWDFLESLRDVFVKDAPAQELFATDKAEYDTIPVGKVKLR
                     FTTNHDESAKMSPIKEFGDMRGSMAAFVLTTYLHGGALIYGSQEAGYPEAINFFTYVPV
                     DWTGNSELYQEYCRLMALYNEYPAIRKGGLTTYPQPDVLLFEKQDGKDRVLVAVNVRNR
                     EVNVTLPQEWNGHPSKDMYSGTEEKLEAELSLCPYQYRIFKY"
     gene            complement(3816..5159)
                     /gene="nplT_3"
                     /locus_tag="BcellWH2_02437"
     CDS             complement(3816..5159)
                     /gene="nplT_3"
                     /locus_tag="BcellWH2_02437"
                     /EC_number="3.2.1.135"
                     /inference="ab initio prediction:Prodigal:2.6"
                     /inference="similar to AA sequence:UniProtKB:P38940"
                     /codon_start=1
                     /transl_table=11
                     /product="GH13"
                     /protein_id="ALJ59676.1"
                     /translation="MRIKDILKILCSSLLLLSFTGCSSDDDPDMPPPADDVTTDGMVIY
                     EANPALFGETQALNGLTAQLPRIKKLEANVLWLMPIFQQGEKNAVGSPYCVKDYRAINP
                     AYGTLSDLKALVTKAHAEGMLVILDWVANHTAWDHAWTTEHKDWYTQDANGNIVSPPGM
                     GWDDVADLNYDNTAMRAAMQEVMLYWLTEADIDGFRCDHAEGVPNDFWKETITKLRAAK
                     STLLMLAEGSQTALYDAGFDMLYAWNFAYKLQDVYAGSASVANLYDTHRSELASVTDKR
                     LLMRYSTNHDMASEKSPVQAYQTKEGAFSAFVASISMGGCPMIYSSQELAYDKALSFFG
                     YQAMDWNSNADYQADYTKLMQLYRNSPALQNGEIKLYQTSKAICSYRISSTEKILVLIN
                     TSGNQERLNLPMERVGDSAKNLWTGESTVLPRTITLEPYQYYIWKIEG"
     gene            complement(5323..7002)
                     /locus_tag="BcellWH2_02438"
     CDS             complement(5323..7002)
                     /locus_tag="BcellWH2_02438"
                     /inference="ab initio prediction:Prodigal:2.6"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ALJ59677.1"
                     /translation="MKKIIYWLFMLPLFALLNGCDDTDTIIFDDELPQFEIKANAILLE
                     VIMPKGSAADDEYYIVGDFNGGAEAAVGNLEWQLEKATGSESKWGIYLLPSTFKDGKTL
                     ADGFYFVSASKGEERSVKNEAVVHQLDVKVGTRTNVWVDRWEAYFNTEEEGHDGFVVYV
                     ADKSGWDNLYLYGWAGAGDVTPAWPGIAVKGTEVINGVTYKYFDMGKALDGYEGVNLIF
                     NNNDGKQFDGPVVTLNRNFYFRITDKGFEEIDPEASYCIYVDDQSGWGDLALYISGAGD
                     NNEDWPGLEPAGTKEINGVVYKYFETDVELMNQSLKLTFNNNKKEDDPGLVLSFVKNIT
                     FSRDFYFSITPEKCEEIDPATHGTSYSLYVEDNTGWNVLALYGYGEAAIGSSWPGIQVS
                     ETKEINGTTYKCFHLTPACTNKNINLIFNDNGVGNQLKDYNLTIDRDYYLRISEAGCSE
                     IKDCTVYVQDNSGWEALTLYGWGDAAIGDSWPGIQVTGTREINGVTYKYFDLSEHVGKY
                     SNLIFNNNGGGQQIEDGGLYTVLIGDIYFSITATSYEKLPKP"
     gene            complement(7021..8817)
                     /locus_tag="BcellWH2_02439"
     CDS             complement(7021..8817)
                     /locus_tag="BcellWH2_02439"
                     /inference="ab initio prediction:Prodigal:2.6"
                     /inference="protein motif:Pfam:PF07980.5"
                     /codon_start=1
                     /transl_table=11
                     /product="SusD family protein"
                     /protein_id="ALJ59678.1"
                     /translation="MKYLKYKCLLAIILGCSLSGCFDLTEEVFDRVDSGVYYQDENSVK
                     SAVATIYSTGATSYAEYFWYMQEFPADQVTWRVWNGGQWGYDEGEKFIFSIQNWTPDAK
                     IIRSAWENAWTTIGLCNTLLADMGKLTSADLKMTDEKLKAYEGEVRTLRAWAYYNIFEI
                     WGGALPLNIEPATVDGELPPTADPDFDTSCKKIYNFIATELDDCYEGMVENQVNRMNKA
                     VNRMIKARLLLNAEVFIKESHYTECAELCREIISGKYGKYELAKDYRDIYSINNTECPE
                     VIMAFACEDGKLNMGWMRMTFYPYNIWDYFGGTYSQSGWNCTCLVPSYDNAGTVNELGG
                     TQGATCFLDAAYGDKLGAVYERFDDRDIRKKNYNYDKKNGYSGIFLKGTIKANYGKGEA
                     LKADADRDGQDLAYVDQVGTFMNLGRNLETVMSPRWGETNSGLRLVKYPVYPTSAAIDF
                     QNIDEVEFRLSEVYYMLAECEMRAGQADKAKELVNEVRKRYFSAGDWADVKDKPGRGFT
                     AFDMDWMLSQWGVEFLNEGRRRRTDLRRFDKFTQGQWWFFGRATDNGQLYPAKRDRKYE
                     WYPLPASALLVNQGLIQNPNYK"
     gene            complement(8952..11930)
                     /locus_tag="BcellWH2_02440"
     CDS             complement(8952..11930)
                     /locus_tag="BcellWH2_02440"
                     /inference="ab initio prediction:Prodigal:2.6"
                     /inference="protein motif:Pfam:PF00593.18"
                     /codon_start=1
                     /transl_table=11
                     /product="gnl|TC-DB|Q45780|1.B.14.6.1"
                     /protein_id="ALJ59679.1"
                     /translation="MNVKRTKLCLCRSLLLMAGLLFAVASFAQDLTVKGKVTDTTGETV
                     IGANVTVKGTTNGIITDIDGNYTLSGVKPSSVLVFSFIGYKTQEIPCSGRQEINVVLSE
                     DAQALDEVVVVGYGSLSKKELSSSIVQVDRSKFLQGSMNNPMEMLTGKVAGLTVNNTAA
                     ANPNASSSLQIRGATSISASNDPLVVIDGVAGGDIRNLAAQDIESMTVLKDAASAAIYG
                     TRGANGVILITTRKGAGEAGRAQVTYDSWFGVNLAKSGPDILSADEFRRSRRATDYGYS
                     TDWYDLLLRDFSYDNNQYLSIDGSTKNGYYGASFNYKKATGLDLNSSREEFGGRFVLNQ
                     RMMDGIVELNGSLNARRVNEVWGNDGMFDTALSMNPTMPLYNEDGTYFQPTSPTGARNP
                     VQELKEIDNNGQRVYLLGTAEVKVNLIRSEKQMLNTSLSYSLHYNDLKQHYYTPSTAGE
                     SYWNGYNGRAEVTYQKWYTSRLEWLGNYSLDLGDHNFKVMVGYNYEQTTWERLQAGNSD
                     FNFDDILWNNLGSGSYLAKGKASMGTGKSLAKLIGVFGRINYNWKNLLIASASIRYEGS
                     TKFGADHKWGAFPSLSLAWEMANMGFLKDHQNIVQSLKPRVSYGVTGRSDFDCYQSLAT
                     YGSHKNAQLNVTDTYLMDGAWVTGYAPSVNANSKLGWEKSVSMNIGVDFALWNRLRGSV
                     EWFDRQSRDLLYNYTAPQPPYIYSTILVNVGTTVNRGIEVSLEGDAFKGTPVEWTTGIN
                     YSYGTTKLDKLSNSLYKASYVELYQKPGVGTSEYFFRVEEGSKIGQFYGYEYAGVENGD
                     MMIYTDEGEKVPVSKADVKYKRHIGNGTPTSYLSWSNTLRYKNFDLSLMFNGAFGFEIF
                     NMRRYGMGLKGCGTDNVLRDAYGKDADITTGGGVISSFFLEKGDYFKLDNLTLGYTITP
                     KENKFIKGMRVYLTAKNLFTLTGYSGNDPSAVAINGLTPGVDTNSAYPSATQLSVGLNI
                     RFK"
ORIGIN
        1 ttagcggatg gttttcaaac ctttcatctc cgctttatca gcctctttga tgctgatggc
       61 aacgccaccg ctggcggcta atttctgttt caatacactc ttaggtgtca ctactacctt
      121 acgtatacga tagctttggg gattggtgtc ccaatctgca tccttgccat cttcgtaaat
      181 ggtagcgata tattgttttc cttccggaag ccaggagaaa ggaatcgtcg ccgtacgact
      241 attctcatca gtaatgccgc caacaaacca ttcgttttta cctttcgcct tgcgggctac
      301 ggtgatataa tctcccggtt cagcttccag gtaccagcta ttgtcccaat ctaccgcaac
      361 gtcttcaatg aatcggaagg catccgggaa acgggcgtaa ttggaaggca agtcggctac
      421 catctggata ggagaaggca tggtcatgta gagtgccatt tgcttcacca aagtggtatg
      481 cacacgttcg ttgggtttct caccgttgta ataagacagt cttgtctcga aaatacccgg
      541 ggtatagtcc atcggaccac ctttcaggcg ggtaaaaggc agaatacagg tatgatcggg
      601 atcattgcca cccattgttt cgaactctcc gccacgggca gattcctgag ccagccagtt
      661 agggtaagta cgacacaaac cggtggggcg tactgcctcg tggctattaa ccattacttt
      721 ataatcagca gcgcgacggg ctacatggat gtaatggttg ttcatccatt gggaagagtg
      781 gtattcatta cgggggatga tataacctac gtaaccggtt ttcacagcat gataaccatt
      841 gtctaccatg aactggaagg cctcatccaa ttggcgttcg tagtcggcag cattggcggc
      901 tgtttcgtga tgcatcacca tttgcacgcc tttttctttg gcgtaacgtt gcagctcttt
      961 aacgtcgaag tcgggatagg ctttgttgaa gaggaactga cggtctttcc ggtaagaagc
     1021 ccagtcttcc caaccttcgt tccagccttc taccagtatt ccgtcgatgc catgggcgga
     1081 ggcgaagtcg atatattcct tcacatgggc ggtattggcg ggatgatgac cattgggttt
     1141 cagtttggca taatccgtaa tgccgggttt ggcctggtag aaatcactat atgcccaggt
     1201 ctttccttcg cctgtgaaca tttcccacca cacgccgacg aatttcatcg gacgaatcca
     1261 agaggtatct tcatattggc aaggttcgtt cagattataa atcaattgag aagcaagaat
     1321 gtcacgggca tcatcgctaa caataacggt acgccaggga gacagcacgg gcagttgcaa
     1381 gtaacctttc ttacctaatt tatcgggagt caggtgggca cttaatttaa actgcttatc
     1441 atctacattt agcaacatac cggcataatc cactaaagca gcttcatgga tattcaggta
     1501 gatgccatct tcgcttttca tcattaacgg ggtttgcact gtcaggccgc cttcggcttt
     1561 agattcataa gatttcttgg caattctttt ctccatatcc actgcgatgt ccgatagagg
     1621 ggcggtggta taggcaaact cgttggtatc atagtcaccg gggatgcaaa aggctttatg
     1681 atttcccgtg agattgaatt cggttacttc atcttttacg gtgaggtagt tcatcttgcg
     1741 ttgcaaaggc agttcgtagc gaaagcccag accatcattg aacagacgaa aacggatatt
     1801 taggatacgt cccgtttccg gttgttctaa ggtgacggtc atttcgttat aatgattccg
     1861 tacccggttg tactcacccc aaacgggatt ccagtagtta tcaacagaag cacgttcaag
     1921 gtttgtttgt ttgaatcctc gggtcaggtc ggcttcttcc gtcaggagac ctaaacgacc
     1981 ggaagttaaa acgggtttgc ctttatagtc cagccggtat gccggaacgc cgtctgcctg
     2041 ctccataaac tccaatgaca ggttaccgtc aggagaagtg agttgctggg ccgaggcgaa
     2101 cgaaccgagg caaaggaaaa aggcaataaa aagagaatgt ttcatattct attatggttt
     2161 tagtattata cataaactga taatttacaa gacgaacatt gaaagacaga actatcccaa
     2221 ttcccctcat cttgggagga ggggtgccca aagggcgggg tggtaggtag ggaaaagatt
     2281 ccttagactt atgattgata ggtattttat tgctttacct accacctccc cctacgggta
     2341 ctccaccccc tccggctccc ccgttatcgg gggagagcaa ttcccaggag gaggagaatt
     2401 aagttactcc atattacagt tactccatat tataaatact tcgtaattat atcgaacttg
     2461 ataaattatc attcatatca tcatattatc aatacttaaa gattcgatac tgataagggc
     2521 acaggctcag ttctgcttcc agcttctctt ctgttccgct atacatatct ttacttggat
     2581 gtccgttcca ctcttgcgga agcgtcacat ttacttcacg attacgtaca tttacagcaa
     2641 ccaacacacg atctttacca tcctgtttct caaatagtag cacatcgggt tgcgggtatg
     2701 ttgtcaatcc ccctttacgg atagccggat actcgttgta aagagccatc agacggcagt
     2761 attcctgata cagttcactg ttccccgtcc aatccaccgg aacatacgta aagaagttga
     2821 tagcttcggg ataacccgcc tcttgtgaac cataaatcaa cgctcctcca tgcagataag
     2881 tagtcagcac gaaagctgcc atagagccgc gcatatctcc gaattcttta ataggcgaca
     2941 tctttgccga ctcatcatga ttggtggtaa aacgcagttt cacttttcct acggggatag
     3001 tgtcatactc cgccttatcc gtagcaaaca gttcctgtgc cggagcatct tttacgaata
     3061 catcgcgaag tgactccaga aagtcccagg aataattcat atcgaaacct gcatcaaagt
     3121 gatcgcgtct tttcccttca gccagcatca gcaacgaacg ctcggggatg gcacgcaaag
     3181 aatcgagcgc ctgtttccag aagtcgaaag gaacaaagtc cgccgcatcg caacggaagc
     3241 catcaatgcc gatttcagta acccaaaact tcatggcttc aatcattgcc aggcgcatct
     3301 cctgattatc aaagtttaag tcagccacat ccttccaacc ggttccggca ggaaagatta
     3361 tgtttccggc ctcatcctgc gtataccatt ctttgttggc aatccaagca ttgtcccagg
     3421 aagtatgatt ggctacccag tcgataatca cattcatccc cttctgatgg caagtggcaa
     3481 ccaaggcctt aaactcatcc agtgtaccga actccggatt cactcctttg tagtccttca
     3541 cacaataggg ggaattcaca gatttctcct gccccacttc attgatcggc ataaaccaca
     3601 ccacgttgat tcccaatgcc tgaatggaat ctaagcgacg ctccaccgcc ttgaatgact
     3661 tctcaggagc aaacactcgc ggattgacct gatacatcac cacatcttcc acagcaggca
     3721 atgccgcaat ttccaccgcc gcttcgccct gccgcttacc tgtacaggca gcaagcagac
     3781 acagcaggct tacaacaaat atatatttct tcatattatc cttctatttt ccagatgtaa
     3841 tattgatagg gctccaacgt aatcgttctt ggcaacacgg tgctttctcc ggtccagaga
     3901 ttcttcgcac tatcccctac ccgctccata ggcagattca atctttcctg attaccactg
     3961 gtatttatca gtaccagtat cttttccgta ctggagatac gataagagca tatcgcttta
     4021 ctcgtctgat aaagtttgat ctctccattc tgtaaagcag gagaattgcg atacaactgc
     4081 atcagtttgg tataatccgc ctgataatcg gcattagagt tccagtccat cgcctgatag
     4141 ccaaagaaag agagggcctt gtcataagcc agttcctgcg aactataaat cattgggcag
     4201 ccacccatag aaatagaggc cacaaaggct gagaaagcac cttccttggt ttgataagcc
     4261 tgcacgggcg atttctcgga agccatatca tggttggtgg aataacgcat aagtaaccgt
     4321 ttatctgtta ccgaagcaag ctcactacga tgtgtatcat acaaattagc cacagaagcg
     4381 cttcctgcat atacatcctg tagtttataa gcgaagttcc aggcatacag catatcaaag
     4441 cctgcatcgt agagtgcggt ttgtgaacct tcggccagca tcagcaaggt acttttggcg
     4501 gcacgaagct tcgtgatagt ttccttccaa aagtcattgg gcacaccttc ggcatggtcg
     4561 caacggaatc cgtctatgtc agcttcggtc agccagtaaa gcataacctc ctgcatggcg
     4621 gcacgcatgg cagtgttgtc ataattcaaa tcagccacat cgtcccaacc cattccgggg
     4681 ggagaaacaa tattgccgtt ggcgtcctgc gtataccagt ccttatgttc cgtagtccag
     4741 gcatgatccc aggcggtatg gttagctacc cagtccagga ttaccaacat accttcggca
     4801 tgggccttcg tgactaatgc tttcaaatcg gacagtgttc cataggcagg attaatagcc
     4861 cgatagtctt tcacacaata cggagaaccg acagcattct tttcaccttg ctggaaaatg
     4921 ggcatgagcc aaagaacatt ggcttccagc tttttgatac gcggcagttg ggcagtcagt
     4981 ccattcagtg cttgcgtttc accgaagagt gccggattgg cttcataaat caccattccg
     5041 tctgtagtaa cgtcatctgc gggaggcggc atgtcaggat catcatccga actgcatccg
     5101 gtaaagctca acagcaaaag gctggagcac aaaatcttaa ggatatcctt tattctcata
     5161 tctatttaat taattgagat agtataagtt ataatttcaa ataatctgtt tcaagcaatg
     5221 aaactaagag tttctcggtg tgaaacagag agtttcaagt aatgaaacta cttgttccaa
     5281 ggcatgaaac aaacggtttc ccatcttgaa actcaaagca tcttagggct tgggcaattt
     5341 ttcataagaa gtagctgtga tagagaagta gatatctcct atcaatactg tatacagccc
     5401 gccatcttct atttgctgtc cgcctccatt gttattgaaa atcagattcg aatacttacc
     5461 tacgtgctcc gataaatcaa agtacttata tgtaacacca ttgatctccc tcgttccggt
     5521 tacttgtatg cccggccaac tgtcgccaat tgcagcgtcg ccccagccat agagagtcaa
     5581 agcttcccaa ccggagttat cctgtacata cacggtgcaa tcttttattt cactacaacc
     5641 cgcttccgag atgcggagat agtaatcgcg atctatcgtc agattatagt ctttcaactg
     5701 atttccaacg ccgttatcat tgaatatcag gttgatattc ttatttgtgc aagccggtgt
     5761 caaatggaag cacttatacg ttgtaccgtt gatttccttc gtttctgaaa cctgtatgcc
     5821 gggccagctg ctaccaatag ccgcttctcc atagccatac agcgccaaca cattccaacc
     5881 ggtattatcc tccacataaa gggaataact tgtaccgtgt gttgcaggat ctatctcctc
     5941 acacttctca ggagttatgc tgaaatagaa atcgcggctg aaagtgatgt tctttacgaa
     6001 agacagcacg agtcccggat cgtcttcctt tttgttatta ttaaatgtca gcttcagact
     6061 ctgattcatc aattccacat cggtttcaaa gtatttataa actactccgt tgatttcctt
     6121 cgttccggca ggttcgagtc ccggccagtc ttcattgtta tcacctgccc cggagatgta
     6181 aagtgccaga tctccccaac cggactggtc atccacatag atgcaataac ttgcttccgg
     6241 gtctatctct tcaaagcctt tatcggtaat gcggaagtag aagtttctgt tgagtgtcac
     6301 caccggaccg tcaaactgct ttccatcatt attattgaaa attagattca caccttcata
     6361 accatccaga gctttcccca tatcgaagta tttataagta accccattga tcacttccgt
     6421 acctttcacc gcaatacccg gccaagcagg tgttacatca ccggcaccgg cccaaccgta
     6481 caagtaaaga ttatcccaac cggacttatc agccacataa accacaaagc catcatgtcc
     6541 ttcttcttcc gtattaaagt aagcctccca gcggtctacc catacattgg tacgggttcc
     6601 cacctttaca tccaactgat gcaccacagc ttcattcttc accgaacgtt cttcaccttt
     6661 cgaggccgat acgaagtaga agccgtctgc cagcgtcttt ccatctttga aagtagaagg
     6721 tagcagatag attccccact tggactcact accggtagct ttctccaact gccattccag
     6781 attacctaca gcagcttcgg ctcctccgtt gaagtcgccc acaatgtagt attcgtcatc
     6841 ggcagcactg cctttcggca tgatgacttc cagtaatata gcgttcgcct tgatttcgaa
     6901 ctgaggcagt tcatcatcga atataatcgt atctgtatcg tcgcacccgt tgagcagagc
     6961 aaacaacggc aacataaaca gccaataaat tatctttttc atggattttc tgtttttgag
     7021 ttatttataa ttcgggttct gtatcagtcc ttgattgaca agcaatgcag aagcaggcaa
     7081 cggataccac tcatatttac gatcacgctt ggcgggataa agttgaccat tgtccgtggc
     7141 acgtccgaag aaccaccact ggccttgcgt gaatttgtcg aaacgacgca ggtctgtacg
     7201 gcggcggcga ccttcattca ggaattcaac accccactga ctcaacatcc agtccatatc
     7261 gaaagcagtg aagccacggc ccggtttgtc tttcacgtct gcccagtcgc cggcactgaa
     7321 gtaacgttta cgtacttcgt tcaccagttc tttggccttg tcggcttgtc cggcacgcat
     7381 ttcacactct gccagcatat agtacacttc gctcaggcgg aattccactt catcgatgtt
     7441 ctgaaagtcg atggctgcgg aagtaggata taccggatac ttcaccagac ggaggccgga
     7501 gttcgtctca ccccaacgcg gtgacatgac ggtttccagg ttgcgtccga ggttcataaa
     7561 cgtacctacc tggtctacat acgccaagtc ttgtccgtca cggtcggcat cggctttcaa
     7621 ggcttcaccc ttaccatagt tagcttttat ggtacctttc aggaagatac cgctgtagcc
     7681 gttcttctta tcataattat agttcttttt acggatgtcg cggtcgtcga agcgttcgta
     7741 gactgcaccc agtttatcac cgtaagccgc atcgaggaag caggtagctc cctgtgtacc
     7801 tcccaattca ttcaccgttc ccgcattgtc atacgaagga accagacaag tacagttcca
     7861 accactctga ctgtaagtgc ctccaaaata atcccagata ttataaggat agaaagtcat
     7921 gcgcatccat cccatattca gtttaccgtc ttcgcaggca aaagccatga tgacttcggg
     7981 acattccgta ttattgatag agtaaatatc gcggtaatcc tttgccaatt catattttcc
     8041 atatttaccg ctgattattt cacggcacag ttcggcacat tcggtatagt ggctttcttt
     8101 gatgaacact tcggcattca gcaacagacg ggccttgatc atacggttca cggccttgtt
     8161 catgcggttc acctgatttt ctaccattcc ttcgtagcaa tcatccagct cggtagcaat
     8221 gaagttataa atcttcttgc aacttgtatc gaagtccggg tcggcagtgg gtggcaattc
     8281 accgtctacg gtggccggtt caatattcag cggcaatgca ccaccccaga tttcaaagat
     8341 attataataa gcccaggcac gaagtgtacg tacttcgcct tcataagctt tcagtttctc
     8401 atcagtcatc ttcaggtcgg cagaagttag ctttcccata tcagccaata aggtgttaca
     8461 caggccgata gtggtccatg cattctccca ggcactacgg ataatcttag catcgggagt
     8521 ccagttctga atggagaaga taaacttttc accttcatca tatccccact gaccgccatt
     8581 ccatacacgc caggtcacct gatcggcagg aaattcctgc atgtaccaga agtattcggc
     8641 ataactggta gcacctgtgg aataaatagt agctaccgca ctcttcacac tattctcgtc
     8701 ctgataatag acaccggagt ctacacggtc gaacacttct tccgtaaggt cgaagcaacc
     8761 gctcaatgaa caacccagaa tgattgccaa cagacattta tatttcagat atttcataat
     8821 tcttttctgt atttagttat taaaggagtt gacaaggctt caggcgacaa gttgacaagg
     8881 ggaaatgact ctcttactaa acgaaactat tatcctcgtt cccttgttaa ctgcaacctt
     8941 gttaactata tctatttgaa acggatattc aagcctacgc tcaactgagt agccgaagga
     9001 taggcactgt tcgtatctac acccggagtc agtccgttga tggcaacggc tgagggatcg
     9061 ttaccggaat aaccggtcag cgtaaacaga ttcttagctg tcagataaac tctcatacct
     9121 ttgatgaact tgttttcttt cggagtgatg gtatatccca gagtcaggtt atccagctta
     9181 aagtaatcac ccttttcaag gaagaaagaa gagattacac cgccaccggt tgtaatatcc
     9241 gcatcttttc cataagcatc gcgcagcaca ttgtccgtac cgcaaccttt cagacccatt
     9301 ccgtaacgac gcatattgaa gatttcaaaa ccgaaagcac cgttgaacat caggctcagg
     9361 tcgaagttct tataacggag cgtattactc caggaaagat aagaggtcgg cgtaccatta
     9421 ccgatatggc gtttgtactt cacatctgcc ttggatacag gaactttttc gccttcatcg
     9481 gtataaatca tcatatcgcc attctctaca ccggcatact cgtagccata gaactggccg
     9541 atcttgctgc cttcttccac gcggaagaag tattcactgg tacctacacc cggcttctga
     9601 tacagttcca cataagaagc tttgtacagg ctgttggaga gtttatccag tttcgtagtg
     9661 ccgtaagagt agttgatacc cgttgtccat tctacgggag ttcctttgaa agcgtcgcct
     9721 tccagagaaa cttcgatacc acgattcaca gtggttccta cgtttaccag aattgtagag
     9781 tagatgtagg gaggctgtgg agccgtatag ttataaagca agtcgcgtga ctggcggtcg
     9841 aaccattcaa cagaaccacg caatctgttc cacaaggcaa agtcaacacc gatgttcata
     9901 ctgacactct tttcccagcc cagtttggaa ttggcattca ctgaaggagc ataacctgtt
     9961 acccaggcac cgtccatcag ataggtatcc gtaacattca actgggcatt tttatgagag
    10021 ccgtaagtgg ctaatgactg gtagcaatcg aagtctgaac gacctgttac accataggaa
    10081 acacggggtt tcaaactctg aacgatgttt tggtggtctt tcaggaaacc catattcgcc
    10141 atttcccagg caagagaaag agacgggaaa gcaccccatt tatgatctgc accgaatttc
    10201 gtagagcctt cgtagcggat ggaggcggaa gcaatcaaca gattcttcca attatagttg
    10261 atacgtccga agacaccgat cagtttggca agagatttac cagtacccat acttgctttt
    10321 cctttggcaa ggtaagaacc gcttccaaga ttattccaga gaatatcatc gaaattgaaa
    10381 tcactgtttc cggcttgcag gcgctcccag gtggtttgct catagttgta acctaccatt
    10441 accttgaagt tgtgatcacc cagatccaac gagtagttac ccaaccactc caggcgggac
    10501 gtgtaccact tctggtaagt cacttctgca cgtccgttat aaccgttcca gtaagattca
    10561 ccggcagtgg aaggggtata atagtgttgt ttcagatcgt tgtagtgcaa agagtagctc
    10621 aatgaagtat tcagcatttg cttttccgaa cggatcaggt tgacttttac ctcagcagta
    10681 cccagcaggt aaacacgctg accgttattg tcgatttctt tcagttcctg caccgggttg
    10741 cgtgctccgg taggagaagt aggctggaag taagttccat cctcgttata caaaggcatg
    10801 gtagggttca tgctcagggc agtatcgaac ataccgtcgt taccccatac ttcattcacg
    10861 cgacgggcgt tgagtgaacc gttcagttct acgattccat ccatcatacg ctggttcagg
    10921 acgaagcgtc caccgaattc ttcacgactg ctgttcagat cgaggccggt tgctttctta
    10981 taattaaaag aagcgccgta gtatccgttc ttggtactgc cgtcgataga aagatattgg
    11041 ttgttatcat aagagaaatc acgcagcaag aggtcatacc aatcagtaga atacccataa
    11101 tccgttgcac gacgggaacg acggaattcg tctgcactca aaatatccgg accgctcttt
    11161 gccaggttca caccgaacca gctgtcgtaa gtcacttggg cacgtccggc ttctccggct
    11221 cccttacggg tagtaattag gatcacacca ttggcaccgc gtgttccgta gatggcagcg
    11281 gaagcggcat ctttcagtac ggtcatcgac tcaatgtcct gtgctgccag gttgcggata
    11341 tcgccacctg ccacaccatc aattaccacc aacgggtcat tggatgccga aatagatgtt
    11401 gcaccacgaa tctgaagaga ggaacttgca ttcggattgg ctgccgccgt attgtttacg
    11461 gtcaaaccgg caactttacc ggtcagcatc tccatcggat tgttcataga accttgcagg
    11521 aacttcgatc tgtctacctg cacaatggaa ctggaaagct ctttcttgct caatgagccg
    11581 tagcccacca caacgacttc atccagtgcc tgagcgtctt ctgacagcac tacattgatt
    11641 tcctgacgtc cactacaggg gatctcttgt gttttgtagc caataaagga gaaaacaagg
    11701 acggaagaag gcttcacgcc cgacaaagta tagttaccgt caatatcggt aatgatacca
    11761 ttagttgtac ctttcacggt tacgttagca ccaattacag tttcgcccgt ggtatccgtt
    11821 acttttcctt tcacggttaa atcctgggca aaggatgcca ctgcaaaaag taatccggcc
    11881 ataagaagaa gagaccggca caaacataac tttgttcttt ttacattcat
//
