LOCUS       CP012801               16055 bp    DNA     linear   BCT 16-OCT-2015
DEFINITION  Bacteroides cellulosilyticus strain WH2, complete genome.
ACCESSION   CP012801
VERSION     CP012801.1
DBLINK      BioProject: PRJNA289334
            BioSample: SAMN03852682
KEYWORDS    .
SOURCE      Bacteroides cellulosilyticus
  ORGANISM  Bacteroides cellulosilyticus
            Bacteria; Bacteroidetes; Bacteroidia; Bacteroidales; Bacteroidaceae;
            Bacteroides.
REFERENCE   1  (bases 1 to 16055)
  AUTHORS   Wu,M., McNulty,N.P., Rodionov,D.A., Khoroshkin,M.S., Griffin,N.W.,
            Cheng,J., Latreille,P., Kerstetter,R.A., Terrapon,N., Henrissat,B.,
            Osterman,A.L. and Gordon,J.I.
  TITLE     Genetic determinants of in vivo fitness and diet responsiveness in
            multiple human gut Bacteroides
  JOURNAL   Science 350 (6256), AAC5992 (2015)
   PUBMED   26430127
REFERENCE   2  (bases 1 to 16055)
  AUTHORS   McNulty,N.P.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-SEP-2015) Center for Genome Sciences and Systems
            Biology, Washington University School of Medicine, 4444 Forest Park
            Ave., Saint Louis, MO 63108, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method       :: HGAP 2.0 and Celera v. AUG-2014
            Assembly Name         :: B_cell_WH2_2.0
            Long Assembly Name    :: Bacteroides cellulosilyticus WH2 2.0
            Genome Coverage       :: 209x
            Sequencing Technology :: PacBio; Illumina MiSeq
            ##Genome-Assembly-Data-END##
FEATURES             Location/Qualifiers
     source          1..16055
                     /organism="Bacteroides cellulosilyticus"
                     /mol_type="genomic DNA"
                     /strain="WH2"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:246787"
     gene            complement(1..2325)
                     /gene="bglX_2"
                     /locus_tag="BcellWH2_01926"
     CDS             complement(1..2325)
                     /gene="bglX_2"
                     /locus_tag="BcellWH2_01926"
                     /EC_number="3.2.1.21"
                     /inference="ab initio prediction:Prodigal:2.6"
                     /inference="similar to AA sequence:UniProtKB:P33363"
                     /codon_start=1
                     /transl_table=11
                     /product="GH3"
                     /protein_id="ALJ59172.1"
                     /translation="MKKQILLSLFFLAAYAAAMHSQEKANTMETFIKNLMDKMTVKEKI
                     GQLNLTVSGGFVAGETLEKGLNPLEQRIADGEVGGLFGLKNAAVIKKWQKVAVENSRLH
                     IPLIFGLDVIHGYDVTFPIPLALASSWNMELIEQVARTSAIEASSDGVCWVYSPMVDIC
                     HDSRWGRIAESAGEDPYLGSVIAKAWVKGYQTNNDLSRKDNVMACVKHYALYGAAEAGR
                     DYNTVDMSRQKAMNEYMLPYKAACEQGAGSYMASFNEFEGIPVTANKYLLDDVLRKQWG
                     FNGFVVTDYTGTMELTNHGIGNEVEVTARALKAGIDMDMVSEYFSQHLEEALEKGIIEL
                     ADIDKACRRVLEAKYKLGLFDNPYKYCDEKRAKETLGTRSHVEQACKAAQECQVLLKNE
                     GNLLPLKKSSKVALVGPLGDRAQDMLGCWSGNSEIVRPISLLEGLKEAVGPMGTVTFAE
                     GSYLVADKELEKILVGNSMGFASSGGRRYGVHERSEEEMLQEAIAIAQKSDIIIAALGE
                     NINMNGEGASRSEPDIPEPQQKLLKALVKTGKPVVLVLFTGRPLVLSWEDEHIPAILNT
                     WFLGVQAGPAIADVLFGDANPSGKITASFPRNVGQLPIHYNHKNTGRPQESDDAGYVRF
                     KSNYIDVVNAPLYPFGFGLSYTTYEYGEITLSSKTIPINGKLTAKINIKNTGKRSGKET
                     VQLYIRDVYSTATRPVKELKAFKQVALEAGESREVTFEITVDDLKYYNHDLQYVCEPGD
                     FEVLIGPNSRDLKMSMFTVLQ"
     gene            complement(2328..4838)
                     /gene="bglX_3"
                     /locus_tag="BcellWH2_01927"
     CDS             complement(2328..4838)
                     /gene="bglX_3"
                     /locus_tag="BcellWH2_01927"
                     /EC_number="3.2.1.21"
                     /inference="ab initio prediction:Prodigal:2.6"
                     /inference="similar to AA sequence:UniProtKB:P33363"
                     /codon_start=1
                     /transl_table=11
                     /product="GH3"
                     /protein_id="ALJ59173.1"
                     /translation="MNLKKVFTTFFICCVVFGSVAQNKRQPSIPGDIEIEKKIEALISK
                     MSIEEKIGQMIQLEVNMVTYTDPEYSTEALLSKSEKELAEIIRKFDLGFYYDSKSMTDA
                     NGRPLPEAGYQFYTLSRAINNELGFKLDNDKLDLVFNTYHVGSILNMLGGSYASDVRTW
                     HDAIRQIQESSLKHLNIPCVYGLDQVHGTNYSKGGTLFPQHIGMVATFNRDLAKRMGEI
                     CAYETRACGVPWIFGPTLDIGRKASWPRQYEGVGEDPYLAAEMGVSYLSGLQGDDPNHI
                     GKYHVGTCLKHYFGYGAPDNGIDRTPANITEQDLREKHYAPFLRAFRSGALSAMTNSSI
                     LNGMNGVANKRYLTNWLKEDLNWDGMIVTDWGDIENIRVRDHIAPTKKEAIKLAVNAGV
                     DMMMVPSEYGYGSLLKELVDDGSVSMDRINDAVRRILRLKFRIGLFEMPYTDVEDYPLF
                     GSNEHAAVAKQMAIESEVLLKNENQTLPLKRGKKILICGPNANTMRGLNGGWSYSWQGN
                     NVETFTTSYNTILKAMQNKFGVENIIYEPGVTYAEKEEWYVENTPEIEKVIEKAGAADY
                     IMVCIGENSYAETTGNINDLNLSHNQKSLVKAVQTVGKPVILILNQGRPRLISDLVPDA
                     QAVVNIMLPGNYGGDALADLVAGDENFSGRLPFTYPSHPNSFTTYDFKVCENRETMPGI
                     YNYEAHTNVQWWFGEGLSYTKFDYSNFRVNKTKFTAKDELVFTVDVKNTGECKGKEVVM
                     LFSSDLYASLIPDNRRLRAFDKIELEPGESKTVSLKIRGTDLAFVGAGGKWLLEKGDFN
                     MMIGGKFLNITCVEDYCCTTPNIE"
     gene            complement(5056..6732)
                     /locus_tag="BcellWH2_01928"
     CDS             complement(5056..6732)
                     /locus_tag="BcellWH2_01928"
                     /inference="ab initio prediction:Prodigal:2.6"
                     /inference="protein motif:Pfam:PF07980.5"
                     /codon_start=1
                     /transl_table=11
                     /product="SusD family protein"
                     /protein_id="ALJ59174.1"
                     /translation="MKKYKNLLLALFVALASGCSDMLDIKPTSFISDEAIWEDKVLIDK
                     FVANTYGSMLCGFNRCTAGFGQNWSMSWAGNMDSATDDFASVSDSPIYTQLNKDAITAQ
                     SCPFVSEIWIQEYLVIRKCNTIIERVAGVDDKVLTAKEKLRIDAEARFLRAFCYFDLGR
                     TFGKAPLILKAQNLEEDLLVAPSSFAEIVEFVKDECDLYADNLPLTYPEEEAGHATKGA
                     FLALKSRALLYLASPLNSEDDARKWDDAAVAAQAVMDLHVYELYKMGETPYRSMEFDKT
                     AANKEVIFERRFSFPEAPHNIHMMWSLDAEDAGSWNGLYPTQNLVDAYETIDGKLIDDP
                     TNTMYDAQDPYSNRDARFYQSIIYNGSTWETYLMSMVTNTVDPSKNGSCKPRLGKARCG
                     YGPKKFIEELDPSTNIYGGYAQSNNWPYFRYAEVLLNYAEAKNESLSVPDESVYNAVNE
                     VRARSNQPNLPTGLSKEEMRKRIKNERRVELLLEEHRFYDLRRWKDGNVLAEPIMGMNI
                     YNNNITLKYEISKVEDRVFTGEHYYLPIPLSEQEKNPLLKE"
     gene            complement(6753..9833)
                     /locus_tag="BcellWH2_01929"
     CDS             complement(6753..9833)
                     /locus_tag="BcellWH2_01929"
                     /inference="ab initio prediction:Prodigal:2.6"
                     /inference="protein motif:Pfam:PF00593.18"
                     /codon_start=1
                     /transl_table=11
                     /product="gnl|TC-DB|Q45780|1.B.14.6.1"
                     /protein_id="ALJ59175.1"
                     /translation="MKKLLLVLFLFVFTLGAVYAQTVQVKGLVISGSDMEPLPGVNVVV
                     KGNTSIGTITDVDGNFSLSVPSDAVLSVTYIGFKSQDVLVKGQRTLKIVLLEDTEALDE
                     VVVVGYGVQKKANLTGAVASIKSDELLKAKSANSTNTLVGQIPGLISKQAKGEPGADDA
                     SLYIRGIATFRGDTSPAFIIDGVERSSADFARMDPNDIESVNVLKDAASAAIFGMRGAN
                     GVVVVTTKRGKQDKTSIKYSGNVSIQSPTKLPEFANSYDYARLYNTFMGQEIYKEDELI
                     KFRDGTDPDNYPNTDWYKEMLSRNAIQHQHNLSVSGGTEKIRYYVSAGFLSQGGLWEDI
                     DYKRYNLRSNIDADITKTTRLGVDVSGRMEKTLNTGSAEGIFAGLVRNTPVLLCRFQDG
                     TFAVPDATHTNIVAANQPGGSYSKGNIFVVDARVDLEQKLDFITSGLSVKGTASFSKNI
                     YKNKSWNVSPYVYTKDAEGEYVLKPRSSASLGLTQNGSEYQEYQLQFNYSRSFGNHNVT
                     AMAMALARKGDFDGSSMNRISFDSEILDQMNAGNSKDQSLSAYDSKTARASYMGRINYN
                     YAQKYLAEFNLRRDGSENFAPSKRWGTFMSASLGWVLSEEKFFEKLKKTVNFLKIRASY
                     GTLGNDNTGGVAFPYYSRFELYSGATASNYLPNNLGDYVFGSLLTKGLVPGAVANAMAT
                     WEKSTKTNIAMDATLFNRLNLTVDFFMERRTDILVQRYDEVPSSFGGTLPLENLGEVKN
                     KGVDFSLSYHQKVREVDFTLGGNFTFARNKIVEMAEAVGTSEYMRKTGRPINGYYGYKT
                     DGIFKSQEEIDAYAKQEVAGTGYVTQPGDIKYVDVSGDGVVNSNDMTYLGNGNIPEIIY
                     GINGALNWKNLDFSFLFQGAARVQVYLQGGVIQPYFNQGNLPQFWVNESWTEQNINAKY
                     PRLTNSIHNNPTTDISGVQTYLYDASYLRLKNIEIGYTFPSKWLKSSAINGLRVYVNAQ
                     NLFTISDVPQIDPENTQQQGWTYPQMKAFNVGLTLQF"
     gene            9877..9972
                     /locus_tag="BcellWH2_01930"
     CDS             9877..9972
                     /locus_tag="BcellWH2_01930"
                     /inference="ab initio prediction:Prodigal:2.6"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ALJ59176.1"
                     /translation="METDNYPYILYKKERDHVSNILQVVYLPSIS"
     gene            complement(9924..11867)
                     /locus_tag="BcellWH2_01931"
     CDS             complement(9924..11867)
                     /locus_tag="BcellWH2_01931"
                     /inference="ab initio prediction:Prodigal:2.6"
                     /codon_start=1
                     /transl_table=11
                     /product="GH157"
                     /protein_id="ALJ59177.1"
                     /translation="MCDNRNFFFNLIIMMNLKTRILKQKLAMLVIMCLLSMTDTWAQFS
                     SSPDVEVKNNSFYIDGKKFFIKGIGYEIGALPGELPNERKFNPDQLHFDIRRILSGGFN
                     TIRTWAAFTEQELEVLRQYDIKIIMGIWIDPAGDFSNTQFVDNAKTIVNDVLSYSKNYN
                     NIIGYLIMNEPHPTAVLGAGYQHTVNLWTELVNIIHSQHPNRPVSIANTPNGTYIHPHI
                     FDFSAYNVYIYNPVTVNYLHGYRNHIDYLQQLNSSDHPLIITEYGLSVSPTGPGGWGYG
                     GNSLSEQESGDVYMYKSLVDGGANGACIFNYSDGWWKADDEFVHSDLPEEWFGLIEYSS
                     LSDKQGHERPVWKAIRDFQSAIIAQPRSEEIYIDKVPVEIFFNDTIKKIKVLLEDKLIY
                     QRDMTDDYLLDTLEIDYKDVKDVRLVFNCYDDKNNLIKTEEKSILITATELTLPTLQLS
                     VNSNCWQTNQVNVTYKVTKSTDFTVSPTFDYVYYPHIGFDYGQKFSSIIGNQNQVEISG
                     RHSISGNIDVFTVGAAFNIYYNGFQKRIFNQMTISRHDLSTGVEENTFVESSLAIRILG
                     DPHSGSLTLVSYADLQLSHVEVVGINGQVIAAYRAESSRLELPVGTLAKGLYLVRAYDM
                     EGRYTTCKMLLT"
     gene            12063..16055
                     /gene="tmoS_6"
                     /locus_tag="BcellWH2_01932"
     CDS             12063..16055
                     /gene="tmoS_6"
                     /locus_tag="BcellWH2_01932"
                     /EC_number="2.7.13.3"
                     /inference="ab initio prediction:Prodigal:2.6"
                     /inference="similar to AA sequence:UniProtKB:Q8KIY1"
                     /codon_start=1
                     /transl_table=11
                     /product="DBD-Pfam|HTH_AraC,DBD-SUPERFAMILY|0035607"
                     /protein_id="ALJ59178.1"
                     /translation="MKMKILSHILGCILFLSCHNSIDERGQKDVAITRQPQIGYNQIKD
                     IVEDKQGYIWIGTPGGVYQYNGKRYYHYRSTEDTTSLCNDAVLKMYCSSRGQLFVLTEF
                     GTSVYNNDGSFQTIFKEGVYPYSNGITETSDGRIFLSISDVGTNIYEYDARNKICTKRL
                     SGFLPLADRNDNLWIWRDGEACCHSIKDFSLIKSIRIDDLSDVAGLLPNGDLFYHTSQG
                     IFIIDPNTFRRVINDSIERVSMVLKNKHIKRVTPYNSSSMLLYAKNNQLYLWDTVKMTI
                     IDQNHTDFPFHIPLDDISTVYVDSHQNVWIGSERDGYQVLYHQQSRFKKETETIEFFRN
                     KDITNIFRGTNNDYYIIVSHSELYHVLADQRIFRLDISSFISKEEIDQCFVDSENLLWL
                     VTNRNLIKCKVYDENKIESLKIYPYYCYTVGEDGTGNIWFESNHNLYYLSKGAETPVAI
                     KENIGIVNTIRKIDSNSIIVSTYAGNIYIVDSNKMTIEEIEIPRSRSTGIVCMDLMIDH
                     TGNAWGVSYGQGLMHIDLTSKKISFYNDTNICGQMCSVIEDCQQNIWIGTLHGLIRFDT
                     ANKRFISYYKEDGIMNDSYVPMCAIHGQGDELIFGGTKGLTLFDPKEIKPYETCKIKIE
                     YISSNEQLLKPYEHKRVKMQGDSIAQVCLTNNNSGVYFYYTTLDYGNLNKYKTEFYLEG
                     LDQQWHSLENEDYAYYSHIPAGHYVLQIRAINENGDVIDAKTVDVFVEPAPWAQKWLLF
                     GVYPLCLLICLYTGWRIYRRIRQNRDQIRKITVQREQEKYANMMNIKYFTNISHEFRTP
                     LTMIYGAFRTLEENPKDSLSSSSLFQVIRHNTERMLKLINQLLDFNKMENGILRLKVSK
                     TNVIPLFNACADRFIVGFQQKKINVRRSIQSETINLLLDDDKFDKILTNILSNALKYSP
                     EEGNISIGIQVITQDIAHAEFPMSMKVKSDEWLEIKVADTGIGIPEDKQKAVFERFYQI
                     EHPDYQSGWGTGIGLFYAKSLVELHHGFIKCSSNAPNGSVFTFIIPMNPALYDNNQQVD
                     SPKGSNAITKIQENVREELNLISPPYQPDDDQAAKILVVDDDTEILNFMKLLLKDYVVE
                     CRTNPNTTIGEIGDIKPDLIISDILMHGMNGYEFCHKIKSDATTCHLPVILLTAQSSSE
                     HQVQGLSAGADAYVVKPFEPRYLTALIKSTLLNREKIRKVLTSSTQIDIQEQPILQSQD
                     GIFMEKLYSYMESHLSEAEIDLGEILNIFSISRSKFYYKVKDLTGLSPNSFFRTYKLNR
                     AAQMIKEGNEKLTYIADVTGFCSQSYFTASFKKQFGCSPSKYKEEY"
ORIGIN
        1 ctattgtaag acagtaaaca tagacatttt gagatcacga ctattcggtc caatcaaaac
       61 ctcaaaatcg ccaggttcac atacatattg taagtcatga ttataatact tcaagtcatc
      121 aacagttatt tcaaaagtaa cctccctact ctctccagcc tctaacgcta cttgtttaaa
      181 agccttcagc tcctttacag gtctggtggc tgtgctatat acatcgcgaa tatataattg
      241 aacagtctcc ttaccgcttc tctttcctgt attttttata tttatcttgg ccgtcaactt
      301 accatttata ggtatcgttt tactggaaag agtaatttcg ccatattcat aggtagtata
      361 acttaaacca aaaccaaacg gatacagagg cgcattaaca acatcaatat aattactctt
      421 gaaacgaaca tacccagcat catcactttc ttgcggacgt cccgtgtttt tatggttata
      481 atgaataggc aattgcccta cattacgcgg gaacgaagcc gtgatttttc cactcggatt
      541 ggcatctcca aataatacat ctgcaatagc cggaccagcc tgcacaccca aaaaccatgt
      601 attaagtatc gctggaatat gttcatcttc ccaggataag acaagtggcc gccccgtaaa
      661 aagcacaagt actaccggtt ttccagtctt caccaatgct ttcaatagtt tttgctgtgg
      721 ttccggaata tccggttcgg aacgagaagc cccctctcca ttcatattta tattttctcc
      781 taaagcagca ataatgatat cagatttctg agcaatagca atggcttctt gcaacatttc
      841 ttcttcggaa cgttcatgaa caccatatct tctgccacca gaagaagcga agcccataga
      901 attgccaacc aatatcttct ccaactcctt atcagccacc agataacttc cttctgcaaa
      961 ggtgacagtt cccattggcc cgaccgcttc cttcaatcct tctaatagtg atataggtct
     1021 gactatctca gaattaccac tccaacatcc aagcatatcc tgtgctctat ctcccaaggg
     1081 tcctaccaaa gccacttttg aactcttttt cagaggcaac aaatttcctt catttttaag
     1141 caagacctga cattcctgag ccgctttaca agcctgttcc acatgactcc gggttcctaa
     1201 tgtttctttt gcacgtttct catcacaata tttatatgga ttatcaaata agcctaactt
     1261 atatttagct tccagcacac gcctgcaagc cttatcgata tcagccagtt caatgatacc
     1321 tttctccaaa gcctcttcca aatgctgtga gaagtattca ctcaccatat ccatatctat
     1381 tccagctttt aaggcacgtg ctgtaacctc cacttcatta ccgattccat gattagtcaa
     1441 ttccatcgtc cccgtataat ctgttacgac aaatccatta aatccccatt gtttacggag
     1501 gacatcatct agcaaatatt tattagcagt aaccggtata ccttcaaact cattgaaaga
     1561 tgccatatag ctacccgccc cctgctcaca agcagcttta tacggcagca tatattcatt
     1621 cattgccttt tgacggctca tatcgaccgt attataatcc cgcccagcct cagcagcacc
     1681 atataatgca tagtgtttga cgcatgccat aacattatcc ttccggctta aatcattatt
     1741 agtctgatat cctttgaccc aggctttagc tatgacacta cccaaataag gatcttctcc
     1801 cgcactctca gcgatgcgtc cccaacggga atcatggcag atatccacca taggagaata
     1861 cacccagcag actccatcgg aactcgcttc aatagcagaa gtccgggcca cctgttctat
     1921 caactccata ttccaagaag aagccagagc tagaggaatg ggaaatgtca catcataacc
     1981 atgtatcaca tccagaccaa aaatcagcgg gatatgcaaa cggctatttt caacagctac
     2041 cttttgccat ttctttatga cggctgcatt tttaagccca aacaaacctc cgacttctcc
     2101 atccgcaatt cgctgttcca atggattaag tcctttttca agagtctcac cggcaacgaa
     2161 tccaccacta accgttaaat tgagctgacc aatcttttcc ttaacagtca ttttatccat
     2221 caggttctta atgaacgtct ccatggtatt tgccttttcc tgagagtgca tcgcagcagc
     2281 ataagcggcc aggaaaaaca gcgataataa aatttgcttt ttcatcttta ttcaatattt
     2341 ggagtagtac aacaataatc ttcaacgcat gtaatattta gaaacttccc acctatcatc
     2401 atattaaaat ctcctttttc caacagccat ttacctcccg caccaacaaa agccaaatca
     2461 gtgccccgga tttttagact aacggtcttg ctttcaccgg gttccagttc tattttatca
     2521 aaagcccgga gacgacggtt atcaggaatc aaagaagcat ataaatccga agagaaaagc
     2581 ataaccactt cttttccttt acattcgccc gtatttttca catcaacggt aaaaactaat
     2641 tcatctttcg ctgtgaattt agtcttgttc actctgaaat tactatagtc gaatttagta
     2701 taactaagtc cctctccaaa ccaccattgc acatttgtat gcgcttcgta gttgtaaata
     2761 ccaggcattg tttcccgatt ctcgcacacc ttaaagtcat aggttgtaaa agaattggga
     2821 tgtgaaggat aagtaaaagg caaacgtcca ctaaaatttt catcacctgc aaccaagtcg
     2881 gccagagcat ctcccccata atttccggga agcattatat tgacaacagc ctgggcgtca
     2941 ggaacaagat cactaatcaa acggggacgg ccctgattca aaatcagaat tacaggcttg
     3001 cctactgttt gtactgcctt caccaggctc ttctggttat gcgataagtt caaatcattt
     3061 atattgcctg ttgtctccgc ataagagttc tcaccgatac aaaccattat ataatcggca
     3121 gctcctgctt tttctatcac tttttctatc tcaggtgtat tttctacata ccattcttcc
     3181 ttttcagcat aggtaactcc aggttcatag atgatatttt ccaccccaaa cttattttgc
     3241 atggctttca atattgtatt gtaggatgtg gtaaaggttt ccacattatt tccctgccat
     3301 gaataactcc acccaccgtt aagtccacgc atcgtattcg cattaggacc acatatcagt
     3361 attttctttc cacgcttcaa cggaagggtc tgattttcat ttttcagcaa aacttctgat
     3421 tctattgcca tctgtttagc aacagcggca tgctcattac tgccaaacaa tggataatct
     3481 tcaacatccg tataaggcat ttcgaataat ccgatacgaa attttaaacg taaaatacgc
     3541 cgcactgcat cattgatccg atccatcgaa acagaaccat catctaccaa ttctttcaat
     3601 agggaaccat aaccatattc agaaggtacc atcatcatat ctacaccggc attaaccgcc
     3661 agctttatcg cttctttttt agtgggcgct atgtggtccc gaacacgaat attctcaata
     3721 tctccccaat cagtcacaat cattccatcc cagttcagat cttctttcag ccaatttgtc
     3781 aaatagcgct tattggccac gccattcatg ccgtttaata tggaagagtt ggtcatggcc
     3841 gacaaagctc ccgaacgaaa ggctctaaga aaaggcgcat aatgcttttc tctcaaatcc
     3901 tgttcagtga tattggccgg agtacggtca ataccattat ccggcgctcc atatccgaaa
     3961 tagtgtttca gacatgtacc tacatgatat ttaccgatgt ggttaggatc atctccttgt
     4021 aagccggaga gataagacac acccatctcc gctgccagat acggatcttc gccaactccc
     4081 tcatattgac ggggccagga ggctttgcgt ccgatatcca gagtcggacc aaatatccag
     4141 ggcacaccgc atgcccttgt ttcataagca caaatttctc ccatacgttt tgccaaatca
     4201 cgattgaaag tggctaccat gccaatatgt tgaggaaaca aagtgcctcc tttggaatag
     4261 ttggtcccat gcacttggtc cagcccatag acacatggaa tattcagatg tttcaatgat
     4321 gattcctgaa tctgtctgat tgcatcgtgc caggtgcgta catccgaagc ataactgcct
     4381 cccaacatat ttaatattga gccgacatga tacgtattga aaactaaatc taatttatca
     4441 ttatcaagtt tgaagccaag ctcattattt atggctcgtg aaagtgtgta aaactgatag
     4501 ccggcttccg gtaaggggcg accattggca tcagtcatac ttttactatc atagtagaaa
     4561 cccagatcaa acttccggat tatctctgct aactcttttt cggactttga tagtaatgcc
     4621 tcggtactat actcaggatc ggtatatgtc accatattta cttccaattg gatcatctgc
     4681 cctattttct cttctatcga catttttgaa atcagggctt cgattttctt ctctatttca
     4741 atatcacccg gaatagaagg ttgtctttta ttttgggcta cactaccaaa aactacacaa
     4801 cagataaaaa aagtcgtaaa tactttcttc aaattcataa caatacaaat aataatgttt
     4861 caattaatac tatcttgcca acaatccgct ttccctacaa aatcataaag tatcagagag
     4921 ggtatgctcc taaaagaaat tctataacca gctcacatca gagcatagaa aatcaaatcc
     4981 ctaaagccag gagtctaact ttagggattc actcccgtta ttttaaggcc agcattgcag
     5041 cggatgattg ctggactatt ctttcagcaa aggattcttt tcttgttcag aaagcggaat
     5101 tggtaaataa tagtgctctc ccgtaaatac ccggtcttcc actttagaaa tttcatattt
     5161 caatgtaata ttattattat agatattcat acccataatc ggttccgcca gcacatttcc
     5221 atctttccaa cggcgtaaat cataaaagcg gtgttcttct aacaataatt ctactctacg
     5281 ctcattcttg attcgtttcc gcatttcttc tttagacaag ccagtgggca gattgggctg
     5341 attagaacgt gcacgcacct cgttgactgc attatataca ctttcatcag gtacactcag
     5401 cgattcattt tttgcctctg cgtaattcag caatacttcg gcatagcgga aatacggcca
     5461 gttgttactt tgagcgtatc ccccatatat attagtagaa ggatctaatt cttcaatgaa
     5521 cttcttcggt ccatacccac agcgagcctt tcctaatctg ggtttgcacg atccgttttt
     5581 cgacgggtct acagtattgg tcaccataga catcagataa gtttcccacg ttgaaccatt
     5641 ataaatgata ctttgataaa aacgggcatc cctgtttgaa tacggatcct gggcatcata
     5701 cattgtattt gtaggatcat caatcagttt tccgtcaata gtctcataag catctactaa
     5761 attctgggta ggatacaaac cattccatga cccagcatcc tcagcatcca aactccacat
     5821 catatgaata ttgtgaggag cttcgggaaa agaaaaacga cgctcaaaaa taacttcctt
     5881 attagcagct gttttatcaa attccataga gcgataaggg gtttcaccca ttttgtagag
     5941 ttcataaaca tgcaaatcca ttacagcctg agccgcaact gctgcatcat cccatttgcg
     6001 ggcatcatcc tcactattca acggactggc caaatacaac agagcccgcg atttcagtgc
     6061 caggaaagct cctttcgtgg catgaccggc ttcttcttcc ggataagtca aaggtaaatt
     6121 atcagcatat agatcacatt catcttttac gaattctaca atttcagcaa atgaggaggg
     6181 agctaccaac aaatcctctt ccagattctg ggctttaagt atcaatggag ctttaccaaa
     6241 agtacggcct aaatcgaaat aacagaatgc acgcaagaag cgagcttcag catctattct
     6301 caatttctcc tttgcagtca gtactttatc atcgacaccg gcaacacgct caataatagt
     6361 attacacttc cgtatcacaa ggtattcctg aatccagatt tcactgacaa acgggcagct
     6421 ttgggcggtg attgcatctt tattcaactg tgtataaata ggtgaatcgg atacactggc
     6481 aaaatcgtct gtagcagaat ccatattccc ggcccatgac atggaccagt tttgtccgaa
     6541 cccggcagta catctgttga acccacacaa cattgaaccg tatgtattag ccacaaattt
     6601 atctatcaaa actttatctt cccaaatggc ttcatcggaa ataaaagaag taggcttaat
     6661 atccagcata tcagagcaac cagatgccaa agccacaaac aatgccaaca ataaattctt
     6721 atactttttc ataatatctt atgcttttga gattaaaact gaagagtaag tcccacgtta
     6781 aacgctttca tttgcggata agtccatcct tgctgctgtg tgttttcagg atcaatttgc
     6841 ggtacatccg aaatagtgaa caggttctgt gcattcacat agacacgcag tccatttatt
     6901 gcagacgatt tcaaccactt ggatgggaat gtatatccga tctcgatatt tttcaaacgt
     6961 aaataagaag catcatagag ataggtctgt acaccactga tatccgtcgt aggattatta
     7021 tggatagaat ttgtcaaacg cggatatttc gcatttatat tctgttcggt ccagctttca
     7081 ttcacccaaa attgaggaag atttccctga ttgaagtaag gttgaataac tccaccctgc
     7141 aaataaactt gcacgcgggc agccccttga aacaaaaagc tgaaatccag atttttccag
     7201 ttcaaagcgc cattgattcc ataaataatt tcaggaatat ttccattgcc taaataggtc
     7261 atatcattag aattgacaac tccatcaccg cttacatcga catatttaat atcacccggt
     7321 tgggtaacat agcctgtacc tgctacttct tgcttcgcgt acgcatctat ttcttcctga
     7381 gatttgaaga tgccgtctgt cttatatcca taatagccat taatgggacg gcccgtttta
     7441 cgcatatatt cagaagtacc tacagcctca gccatttcta caattttatt tctggcaaat
     7501 gtgaaattgc ctcctaatgt aaaatccact tcacggactt tctgatgata actcaatgaa
     7561 aagtcaacac ctttattttt cacctcacct aaattttcca aaggcagtgt tccaccgaaa
     7621 gaagacggaa cttcatcata tcgttgaacc agaatatccg ttctccgttc catgaagaaa
     7681 tctacagtca ggttcaatcg attaaacaag gtagcatcca tcgcgatatt cgttttggtc
     7741 gatttctccc aagtagccat agcattagcc actgcgcctg gtaccaagcc tttcgtcaac
     7801 agagagccaa agacgtagtc gcccaggtta ttaggaagat aattacttgc agtagcacct
     7861 gaatacaatt caaaacggct ataataggga aaagccacac cacccgtatt atcattacct
     7921 aaggtaccat aggaagctct tattttcagg aagtttaccg ttttcttcag tttctcaaag
     7981 aacttctcct ccgaaagtac ccaacctaaa gatgcagaca taaatgtacc ccaccgtttg
     8041 gacggcgcaa aattctcgga gccatcccgg cgcagattaa attcagccag atatttttgt
     8101 gcataattat agttgattct ccccatgtaa ctggcacgtg cagtcttact gtcatacgca
     8161 ctcaatgatt ggtcttttga gtttccggca ttcatctgat ccaaaatctc agagtcgaaa
     8221 gatatcctat tcatgctaga gccgtcaaaa tctccttttc tggccaaagc catagccatt
     8281 gcggttacat tatgatttcc aaaagagcgg gaataattaa actgcaactg atattcctgg
     8341 tattcggaac cattctgagt taatcctaaa ctggcacttg aacgtggttt caggacatat
     8401 tctccttccg catctttagt atacacataa ggagatacgt tccaagattt attcttatat
     8461 atattcttac tgaaagaagc agtcccctta acagacaatc cggaagttat aaaatccagt
     8521 ttctgttcca gatcaacccg cgcatctact acgaatatat tccccttgct ataactccct
     8581 ccaggttggt tagcagcaac aatattagta tgagtagcat cgggcactgc aaaagtacca
     8641 tcctgaaaac ggcataataa aacaggagtg ttacgtacca acccggcaaa gataccttct
     8701 gccgatcctg tattcagtgt cttttccatt cttcccgaaa catccactcc caaacgggtt
     8761 gttttggtaa tatcagcatc aatattgcta cgcagattat agcgtttata atctatatcc
     8821 tcccaaagtc cgccctgact gagaaatccg gcacttacat agtagcgtat tttttccgta
     8881 ccacccgaca cggacaggtt atgttgatgc tgaatggcat ttcgtgacag catttcttta
     8941 taccaatccg tattcggata attatcagga tctgtaccat ctctgaattt tatcaattca
     9001 tcttccttgt atatctcttg ccccatgaat gtattataca gacgtgcata gtcataagaa
     9061 ttggcaaatt ccggcaactt tgtaggagac tgtatagaga cattccctga atatttaatg
     9121 ctcgttttat cctgctttcc ccgcttagta gttacaacca ctacaccatt agcgccacgc
     9181 ataccaaaga ttgctgccga agccgcatct ttcagcacat taacggactc aatatcatta
     9241 gggtccatac gtgcaaaatc tgccgaagag cgttctaccc catcaatgat aaatgcagga
     9301 gatgtatctc cccggaaagt tgcaatacca cgtatataca aagaagcatc atctgctccc
     9361 ggctcgccct tagcttgttt cgagataagc ccaggaattt gccctaccaa tgtattagta
     9421 gaattagcag acttagcctt cagcaattca tcacttttta tagaagctac agcaccggtc
     9481 agattggctt ttttctgaac gccgtagccc accaccacca cttcatccag agcttcagta
     9541 tcttccagaa gaacgatttt aagtgttctt tgccctttca ccaaaacatc ttgagattta
     9601 aaacctatat aagtcactga aagaactgca tcagaaggaa ccgacaagga gaagttacca
     9661 tctacatcag tgattgttcc tatagaagta tttcctttca ccactacatt tactccgggc
     9721 aatggttcca tgtccgaacc acttatcacc aagcccttta cctgaacagt ctgagcatat
     9781 acagccccca aggtaaatac aaacaaaaat aaaaccaaca ataatttttt catataaata
     9841 ataaattaaa gattatcaac ttaaaattct actttcatgg aaacagacaa ttacccttac
     9901 atcttatata aaaaggaacg ggatcatgtc agcaacatct tacaggtcgt atacctcccc
     9961 tccatatcat aagcccggac caggtacaat ccttttgcta atgttcccac aggcaattcg
    10021 agccttgaac tttcggcacg atatgctgca atcacctgcc cattgatacc caccacttcc
    10081 acatggctaa gttgcaagtc cgcgtaacta accaaagtca gacttccact atgcggatca
    10141 cccagaatcc ggatagccaa agaagattca acaaatgtat tttcctccac acctgtgcta
    10201 aggtcatgcc gggaaatcgt catttgatta aaaatacgct tttgaaatcc attataatag
    10261 atattaaacg cagctcctac tgtaaaaaca tctatatttc cggatatact atgccgaccg
    10321 gatatttcaa cttggttctg gttgcctata atcgaactga atttctgccc gtaatcaaat
    10381 ccaatatgcg gataatagac atagtcaaat gtcggactga cagtaaaatc tgtagattta
    10441 gtaaccttgt atgtgacatt aacctggttg gtttgccaac aattgctatt cacagagagt
    10501 tgaagagtag gtaaagtcag ttcagttgca gtgatcaaaa tactcttctc ttctgttttt
    10561 atcagattgt ttttatcgtc atagcaatta aacaccaatc tcacatcttt gacatcttta
    10621 taatcaattt caagagtgtc cagcaaatag tcatctgtca tatctctttg ataaatcaat
    10681 ttatcctcca gtaaaacctt gattttttta attgtatcat tgaagaatat ctcaacagga
    10741 actttatcta tatatatttc ctctgatctc ggctgtgcaa tgattgcgga ctggaaatcc
    10801 cgtatagctt tccaaaccgg gcgttcatgc ccctgcttat ccgacaaact gctatattca
    10861 atcaatccaa accattcttc cggtaaatca ctatgcacaa attcatcatc agctttccac
    10921 cagccatcac tataattgaa tatacaggca ccatttgccc cgccatcaac caaagactta
    10981 tacatatata catctcccga ctcctgttcg gacaaactat taccaccata tccccaaccg
    11041 cccggaccag taggcgaaac ggacagtcca tattcggtta ttatcaacgg atgatccgat
    11101 gagttaagtt gttgcagata atcaatatgg tttctataac catgaagata attaaccgtg
    11161 accggattat agatatatac attatatgca ctgaaatcga atatatgcgg gtgaatataa
    11221 gtaccattcg gagtattggc tatactgaca ggacggttgg ggtgttgcga atgaatgata
    11281 ttgaccagct ccgtccatag attcacagta tgttgatacc cagctcccag aactgccgtg
    11341 ggatggggtt cattcatgat taaatagcct attatattat tgtaattctt ggaataactc
    11401 aacacatcat taactatcgt tttggcatta tcgacgaatt gtgtatttga aaagtcacca
    11461 gccggatcaa tccagatacc cataattatt tttatatcat attgccgaag aacttccagt
    11521 tcctgttctg taaacgcagc ccaggtacga atagtattaa atccaccgga taaaatacgc
    11581 cggatatcga aatgtaactg gtcgggattg aattttcttt cattcggtag ttcccccggc
    11641 aatgctccaa tttcatagcc gataccttta atgaagaatt tcttcccatc aatataaaac
    11701 gaattatttt tcacttccac atccggagaa gaactgaatt gtgcccacgt atccgtcata
    11761 ctcaaaagac acattataac cagcattgcc agtttctgtt tcaggattct tgttttcaag
    11821 ttcatcataa taataaggtt aaaaaaaaag tttctattat cgcacattct gcatttcatt
    11881 tttctgttgg caaagttata tgcatatctg atatatcact gtaaccattc tccaaacctc
    11941 tataaccaag gtccacatat ctgtaatcac agtccgaatg agtataatca aaatccaatt
    12001 gggcatattt cttttgctta actcaccata tattgtaact ttgcctcaaa tatttgtata
    12061 ctatgaaaat gaaaattcta tcccatattt tgggatgtat tctttttctg tcttgtcaca
    12121 acagcattga cgaacgggga caaaaggatg tcgcaatcac ccgccaaccc cagatcggtt
    12181 ataatcagat taaagatatt gttgaagaca aacaaggata catctggatt ggtaccccag
    12241 gtggagttta ccaatacaac ggaaagcgct attatcacta cagaagcaca gaagatacaa
    12301 ccagcttatg taatgacgca gtcctgaaga tgtattgttc ttccagggga caactattcg
    12361 tactgacaga attcgggact tcggtctaca acaatgacgg aagttttcaa actatcttta
    12421 aagaaggagt atacccctac tccaacggga ttacagaaac aagcgatgga agaatctttc
    12481 tcagcatctc agatgtcggc accaatatct atgagtatga tgcgcggaat aaaatatgta
    12541 ctaaacgact ttccggcttc ttaccattag ccgaccgtaa tgataacctc tggatatgga
    12601 gagacggaga agcctgttgt cactccatta aagattttag tctgattaaa tccatccgga
    12661 tagatgacct ttcggatgta gccggattac ttccaaatgg ggacctgttc taccatactt
    12721 cccagggaat attcattata gatcctaata ctttccgccg ggtaatcaat gattccattg
    12781 aacgcgtttc tatggtgctg aagaataagc atatcaaaag agttactcct tataacagtt
    12841 cctctatgct actatatgcc aaaaacaatc aactctatct atgggatact gtaaaaatga
    12901 caatcatcga ccaaaaccat acagactttc ccttccacat accattggat gatatttcaa
    12961 ctgtatatgt tgattcccac cagaatgtct ggatagggtc cgaaagagat gggtaccaag
    13021 tattatatca tcagcaatcg cgatttaaaa aagagactga aaccatcgag tttttccgta
    13081 acaaggatat caccaatatt ttcagaggaa caaataatga ttactatata atagtatctc
    13141 acagtgaact ctatcatgta ctggctgatc agcgcatctt ccgattagat atctcttctt
    13201 ttatttctaa agaagaaata gaccagtgct ttgtcgacag cgaaaacttg ctatggctgg
    13261 taaccaaccg caatctgata aaatgtaaag tttatgatga aaataagatt gaaagtctga
    13321 aaatctatcc ttattactgc tatacggtag gagaagacgg tacaggaaat atatggttcg
    13381 agagcaatca taatctatat tatctcagca aaggagcgga aacacctgtt gctataaagg
    13441 aaaatatagg aattgtgaac actatcagaa aaatagattc taacagcatt attgtcagta
    13501 catacgcagg taacatttat atagtagatt ccaataagat gacaatagag gaaatagaaa
    13561 ttccccgttc ccggagcaca ggaatcgtat gtatggatct gatgattgac cacaccggca
    13621 atgcatgggg agtttcatac ggacagggat taatgcacat cgacctgacc tcgaaaaaaa
    13681 taagtttcta taatgacacc aacatctgcg ggcagatgtg cagtgtaata gaagactgcc
    13741 aacagaatat atggatagga accttacatg gcttaatacg cttcgacaca gccaacaaac
    13801 ggtttatctc atattacaaa gaagatggaa ttatgaatga ttcctatgtt cccatgtgtg
    13861 caattcatgg gcagggtgac gagttgatat ttggaggaac caaagggctc accctattcg
    13921 accctaaaga gataaaacca tacgaaacct gcaagattaa aatcgaatat atttcttcta
    13981 acgaacagct attgaagcca tatgagcata agagagttaa aatgcaagga gatagcattg
    14041 ctcaggtttg ccttaccaat aacaatagcg gagtatactt ttattataca acattagatt
    14101 atggaaacct gaataaatac aaaacagagt tctatctgga aggtttagac cagcaatggc
    14161 attccctgga aaatgaagat tatgcttact attcgcatat tcctgcggga cactatgttt
    14221 tgcaaataag agcaatcaat gaaaatggag atgtgattga tgcaaaaaca gttgacgtat
    14281 tcgtagagcc tgctccctgg gcccagaagt ggttattatt cggagtatac cctttatgtc
    14341 tgttgatctg cttatatacc ggatggagga tctaccgccg tattaggcag aacagggatc
    14401 agatacgaaa aataacagtc caacgtgaac aggagaagta tgccaacatg atgaacatca
    14461 agtatttcac aaatatctct catgagttcc gaactccatt gaccatgata tacggagcat
    14521 tccggacgct tgaagagaat ccgaaagaca gcctaagttc gtccagtctt tttcaggtaa
    14581 tcagacataa taccgaacgt atgcttaaac taatcaatca actactggat ttcaataaaa
    14641 tggagaatgg catcttaaga ctgaaagtat caaaaaccaa tgtcattccc ctattcaatg
    14701 cctgcgcaga tcgctttatt gtagggttcc agcaaaagaa aataaatgtc cggcgttcca
    14761 ttcagtccga aacaatcaat ctcttactgg atgatgacaa attcgacaag atattgacta
    14821 acatactttc aaatgcgttg aaatactccc cggaggaagg aaacatatct atcggaatac
    14881 aggtcattac ccaggatata gcccatgcag aatttcccat gagtatgaaa gttaagtcgg
    14941 atgaatggtt ggaaataaaa gtcgcagata cgggaattgg tatccccgag gataagcaga
    15001 aagctgtttt tgaacgtttt taccagattg aacatcctga ctaccaaagt ggatggggaa
    15061 ccggcatagg cttattttat gcaaaatcat tggttgagtt gcaccatggc ttcatcaaat
    15121 gcagcagcaa tgcgcccaac ggttctgttt ttacctttat tattcctatg aatccggctt
    15181 tatatgacaa caatcagcag gtcgactctc ccaaagggag taatgctata acaaaaatac
    15241 aggaaaatgt aagagaagaa ctgaacttga tatccccacc ctatcaaccg gatgacgacc
    15301 aagctgctaa aatcctggta gtagatgacg acacggaaat tctcaatttc atgaaactgt
    15361 tgttgaaaga ttacgttgtg gaatgcagaa caaatccgaa tacaaccatc ggagaaattg
    15421 gcgatataaa gccggattta ataatcagtg acatcctgat gcatggcatg aatggatatg
    15481 aattctgcca caaaataaag agtgatgcaa ccacatgcca tttacctgtc atattgctaa
    15541 ccgcacaaag ctcgtcggaa catcaggtac aaggtctttc ggcaggtgca gatgcttatg
    15601 tagtgaagcc ttttgagccc cgatatttaa cggcactcat caaatcaaca cttctaaatc
    15661 gtgagaaaat acgcaaagtg cttacttcat ctactcaaat agatatccag gaacagccta
    15721 tactacaatc gcaggatggt atcttcatgg agaaattata ttcatacatg gaatcccatt
    15781 taagtgaggc agagattgat ttaggagaaa tccttaatat cttctcaatc agtcgttcca
    15841 aattctatta taaagtcaag gatctgacag gattgagtcc taactctttc ttccggacct
    15901 acaaactgaa ccgggctgcc cagatgatta aagaagggaa tgagaaactg acatatattg
    15961 cagatgttac aggcttttgc agtcaatctt acttcacagc ttcattcaag aaacaattcg
    16021 gctgttcccc aagtaagtac aaagaggaat actga
//
