LOCUS       CP003170               32089 bp    DNA     linear   BCT 28-APR-2016
DEFINITION  Actinoplanes sp. SE50/110, complete genome.
ACCESSION   CP003170
VERSION     CP003170.1
DBLINK      BioProject: PRJNA76835
            BioSample: SAMN02603081
KEYWORDS    .
SOURCE      Actinoplanes sp. SE50/110
  ORGANISM  Actinoplanes sp. SE50/110
            Bacteria; Actinobacteria; Micromonosporales; Micromonosporaceae;
            Actinoplanes.
REFERENCE   1  (bases 1 to 32089)
  AUTHORS   Schwientek,P., Szczepanowski,R., Kalinowski,J., Klein,A., Selber,K.,
            Wehmeier,U.F., Stoye,J. and Puehler,A.
  TITLE     The complete genome sequence of the acarbose producer Actinoplanes
            sp. SE50/110
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 32089)
  AUTHORS   Schwientek,P., Szczepanowski,R., Kalinowski,J., Klein,A., Selber,K.,
            Wehmeier,U.F., Stoye,J. and Puehler,A.
  TITLE     Direct Submission
  JOURNAL   Submitted (01-DEC-2011) Bielefeld University, Center for
            Biotechnology, Universitaetsstrasse 27, Bielefeld, NRW 33615,
            Germany
REFERENCE   3  (bases 1 to 32089)
  AUTHORS   Schwientek,P., Szczepanowski,R., Kalinowski,J., Klein,A., Selber,K.,
            Wehmeier,U.F., Stoye,J. and Puehler,A.
  TITLE     Direct Submission
  JOURNAL   Submitted (07-MAR-2014) Bielefeld University, Center for
            Biotechnology, Universitaetsstrasse 27, Bielefeld, NRW 33615,
            Germany
  REMARK    Protein update by submitter
COMMENT     A liquid culture of the strain Actinoplanes sp. SE50/110  was
            kindly provided by the company Bayer HealthCare AG, Wuppertal,
            Germany. Identical strain can also be obtained from culture
            collections.
FEATURES             Location/Qualifiers
     source          1..32089
                     /organism="Actinoplanes sp. SE50/110"
                     /mol_type="genomic DNA"
                     /strain="SE50/110"
                     /culture_collection="ATCC:31044"
                     /culture_collection="CBS:674.73"
                     /db_xref="taxon:134676"
     misc_feature    1..32089
                     /note="Acarbose Gene Cluster"
     gene            1..3228
                     /gene="acbZ"
                     /locus_tag="ACPL_3663"
     CDS             1..3228
                     /gene="acbZ"
                     /locus_tag="ACPL_3663"
                     /EC_number="3.2.1.1"
                     /note="Glycosidases"
                     /codon_start=1
                     /transl_table=11
                     /product="GH13_13|CBM41|GH13"
                     /protein_id="AEV84558.1"
                     /translation="MVLSRHRDVMRRLSAVLALGLVVPLLLAPPWRASAAPAGAAEPSA
                     AALAHWGADRPAPAEQFYFVLPDRFADGNPKNDTGGLSGDRLSTGYDPTDKGFYHGGDI
                     QGVIDKLDYIQGLGTTAIWLAPVFKNRPVQGTGAAASAGYHGYWVTDFTQVDPHFGTNA
                     DLKRLVQLAHRRGLKIYLDIIVNHTADVIQNEGGKSTYVDKADAPYRDSRGRPFEDHNY
                     ADGSRPFPKVNLQSFPYTPVFASPADATAKVPAWLNDPTMYHNRGNSLFSGENSEYGDH
                     TGLDDLWTERPEVVRGMTEIYADWIRDADIDGYRMDTVKHSNIEFWQQFNPAIQQAARR
                     AGKPGFFMFGEVFSADQEVESRYVRQGGLAASLDFSFQSAARTFVSGDTPATALADLYR
                     HDDLYTARDTGAGRMPTFLGNHDIGRIGSFITTGGADRTSYLRRDQLAHELMFLTRGQP
                     VVYSGDEQGFTGPGGDKDARQDMFASRTPDYLDDDLIGTDRTHASDNYDTGHPLYRTIA
                     ELGALRKANPALRDGVQITRYAAPGAGIFAFSRVDPVRRQEYLVAVNNATTAQTATVGT
                     ATPGSTFTGVYRAGGTAATGSDGKLTVTVPALSAVVYRGGSPIAVPSARPTVRISAPAA
                     GASVPSRADLVADVTGDPLATVTFAAQAGSGPWTVIGTARQAPYQVHHDLTGLAGGVTV
                     RYKAVVRDGRGRTASSTSSLRVGTPDTHVAPERMVVHYQRPAGDYGAWRLYAFGDIDAS
                     AQTTYPDGQPFAGQDEYGAFAWVRLKPGAKNAGFVVVDGNGVKDVQQDRFVDPGRQPEI
                     WLKAGDATVYPSRQDATGRPDPQPDPKTAVLHYRRADGDYTGWGLHVWDGAAQPTEWTA
                     PLAPSGRDAYGVTFRVPLADGATGVSYVLHAGDTKDQPTDQRIDFAAGREVWLLDGVAE
                     RLLPVTRRTAAGAGIDVTTSRAGWASRDTVVWNTGVGSTLQPVGGGTDGRVYELAYAPV
                     GGITVVGGELAGAYRTLRLTAQRDGLTESQRVRFPKLWRYGAFRVADADRHRLATALRG
                     QVVITERDASGKLLAATGVGAAGDLTG"
     gene            complement(3293..4096)
                     /gene="acbY"
                     /locus_tag="ACPL_3664"
     CDS             complement(3293..4096)
                     /gene="acbY"
                     /locus_tag="ACPL_3664"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease protein"
                     /protein_id="AEV84559.1"
                     /translation="MTVSTARRYLRLTAVLCGASLHRLTAYRMDFLIGAASFVIRIACQ
                     IALIGVIFQYVPALGGWTRQQALFLLGFSLLPRGLDRLFTDQLWILAWQLVRTGDFFRY
                     LIRPVNPFYALLSERFLYPDGFGELATGIAIVVTAAGTMDLHLTVAQWLLLLPLVLGGA
                     LIHTFLKAFLASLSFWMTSSLNVMVAVNQLSEFTAYPLNLYHPVLRGVLTWVLPFAFTA
                     YLPVRYLLTGDAGPLLWMLPVTTLTVLLGYGTFRLGLRRYEMPGS"
     gene            complement(4093..4896)
                     /gene="acbX"
                     /locus_tag="ACPL_3665"
     CDS             complement(4093..4896)
                     /gene="acbX"
                     /locus_tag="ACPL_3665"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease protein"
                     /protein_id="AEV84560.1"
                     /translation="MIRAARRYAPFALAGLHAVTRYRSTIVLSALTAAAATSLQVFLWR
                     AVYAGGPAPAGLPFAQLTSYIVLAQVLGMLHTNRIDEMIAGEVYRGDIAVSLVRPANYA
                     LSCLAVNLPTAALSALLAGAPVLAGFAMFASLPAPPPANLLLFAVALLLSVILAFEINF
                     LVGLAAFVTTNTWGIRTIKNALVAFLAGQVVPLALFPDGVARLLRLLPFQGLIDSPLRL
                     LLGGYSGGSGAAAILGVQALWAVLLYGVLALAWNRSLRRVEVLGG"
     gene            complement(4893..5966)
                     /gene="acbW"
                     /locus_tag="ACPL_3666"
     CDS             complement(4893..5966)
                     /gene="acbW"
                     /locus_tag="ACPL_3666"
                     /EC_number="3.6.3.31"
                     /codon_start=1
                     /transl_table=11
                     /product="gnl|TC-DB|P73329|3.A.1.141.1"
                     /protein_id="AEV84561.1"
                     /translation="MPGYARHARPDGTTGMIVAEHLSKHFKRYRREPGLRGSLRTMFSA
                     RYDVVRAVDDISFEVPSGVKIAYIGANGAGKSTTIKLLTGIMRPTTGRVRVDGLDPHRQ
                     RTRVAGRIGVVFGQRSQLWWDLPVLDSFRILRHVYEVPQAVYDRNMRLFRDRLDLGALG
                     NTPVRQLSLGQRMRAEIAASLLHDPAVVFLDEPTIGLDLVLKQAVRDLINHIHAELGTT
                     VMLTSHDIGDITSICDQALVVDRGTIVHQGTMRDLLRSVDTRAVTFEYAAGSVSEAAAL
                     RIITEGLPEVDATPAESGRIRVEFPVDRWSARQVIAFLLDRFDLSDVLVPDADLETLLR
                     RIYAGSRPEPVTAGDGA"
     gene            6806..8101
                     /gene="acbV"
                     /locus_tag="ACPL_3667"
     CDS             6806..8101
                     /gene="acbV"
                     /locus_tag="ACPL_3667"
                     /EC_number="2.6.1.22"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-keto-6-deoxy-glucose 4-aminotransferase"
                     /protein_id="AEV84562.1"
                     /translation="MSRQADLLARESRHLAPGASEEAALGRRVFVEGRGATLRDADGVE
                     YLDFAAGTLTQSLGHCHPEVVARLTEQAGKLWNVHDFATADRAALCELLAELLPDHLTT
                     LAFFSTGAEVVEAALRTVQAVAEPGRNRVGALRHGFHGKTMGARMLVHWDVGDQSFAGN
                     SVLGYAPYCYRCPLELSYPSCEVRCATLVRRHIAEKPNVSALFFEPVLGAAGVIVPPPG
                     YWEQIAAACRDNGVLLVADEVLTGGGRTGTFLASEAIGVAPDLVTLAKGTASGFPFAVL
                     AGRDEVLRHPRAGLAGSTASTYAGNPLGIAAAHATLSVISRDRLIEQVRDLGAVLADRL
                     AEMHDRHPHLGDVRGIGLLHGLEFVHDRQSRRPAPEIARRVYTTALDAGLRTAIGGHII
                     RLAPPFVIDETELLRGLDLLDRAITEAGRVTA"
     gene            8098..9576
                     /gene="acbU"
                     /locus_tag="ACPL_3668"
     CDS             8098..9576
                     /gene="acbU"
                     /locus_tag="ACPL_3668"
                     /codon_start=1
                     /transl_table=11
                     /product="1-epi-valienol-7-phosphate 1-kinase"
                     /protein_id="AEV84563.1"
                     /translation="MTPRPVSTIDVSLASLLRTADWPHEDLRGPGGVRILDEAILGPSR
                     LLIVAAERNPESRYFVAVLRHDPSREAVGDAAHDRAVVQAMRERLALPTAAGHLIVFDG
                     DPAPFRATRPFDPGWSTNALSLADLDGTLHIHKAYRLVSAATREPHLLRLMHRGGRTQR
                     WAGDYHYVEQPSGRRYPLGLLYAYAEGDSLDLPLRHSIRSMWPALLGGTEPAGAVTAAQ
                     RSIAGELPGVGRFLRDFHTELAQRLEPAPTFPVNAYLRETAERVAALGCRISADERYPR
                     PVREAVVAALTGELDQATTSAVRVPWPAGPSHGDLHLSHILRRQTPDGWRLCVIDLSTP
                     APDPADPLGAAQSPWQDLVALLRGLEIFTADEFVHQAALRLGADQDDTCRTVLLISAGQ
                     TPDTPGWTGSRLTALRRMHDAASVWAGQVRRMLLSGYADGGEAAEEHPAWRIFRLRRLL
                     HELDYAYAHDQHYHAAINLRHVLQTYRPPVTGES"
     gene            9581..11710
                     /gene="acbS"
                     /locus_tag="ACPL_3669"
     CDS             9581..11710
                     /gene="acbS"
                     /locus_tag="ACPL_3669"
                     /EC_number="2.4.1.-"
                     /codon_start=1
                     /transl_table=11
                     /product="GT5|GT0"
                     /protein_id="AEV84564.1"
                     /translation="MHIIETYFECGGFDHRFIQGGTSVYLWQLSRGLADLGHRVSIVTP
                     AHGRLDDLRRLHEVEDLPGTDEYELPLVLDPRVWGERFPAQMDIALRTTAHRIRLAGVD
                     LYFLSNELLDQLPDRFYPPYESKGVDLVFFKPLAYQVAAIRFIRSHFGDQRAIVHAHEP
                     FYHYLMPAAFAADPAKHVVSTVQSNMPINKSVYRAEVARLLGFLGAPNALPADDPAGSR
                     SPHTVAMSQYQQLTHLHYEYPPDHVRVYDLVAEHADRIDFLSPGHRDYYTCFADTPFAQ
                     LFATLPVSRTVRRNADKTFVGGCAVGDEWVTGELPPVDREKVLAGLGLDPDLPAFYHNA
                     RYAVNHKGQVELIRAVDRVLSGGVRASFIVRCLSDAGIADPLFHEVVARHPGRVNLEWH
                     RVPEDQLREYARAADFCLFPSKFEMDTFLIAQGEAMAAGAVPIATAQLGMAHFGHVADP
                     LTGPDAATATGFAVNRSFAEDDPLLVQGLTEQIRRAVTLWNEQPGQYRRLSANAVARAR
                     EFTWRRAAQAHEAAFAGVWAGRTPRLPVGDLLRFGWFDELPADAWTLHRDEIAEVALAH
                     GDADAYLRCRPDDLDALAALFERAWARADFPACARTVELAEEHRQERVPQWRARLAGRG
                     RIDRDGRLHYRPPSAERVELVLPDLAEPLRGTVTVTAMAPTGDTFTGQLPAGTRRADLL
                     LTLSDGRTVWDEVTA"
     gene            11707..12798
                     /gene="acbR"
                     /locus_tag="ACPL_3670"
     CDS             11707..12798
                     /gene="acbR"
                     /locus_tag="ACPL_3670"
                     /EC_number="2.7.7.27"
                     /codon_start=1
                     /transl_table=11
                     /product="1-epi-valienol-1,
                     7-bisphosphate-1-adenylyltransferase"
                     /protein_id="AEV84565.1"
                     /translation="MSTGVRAVLLAGGEGRRMGALGAGRLKPLVPFGGAARLIDFSLAN
                     ARDSGLDQVLLLSQYQERQLMDDLRRTWWQPGFRVHFGPYDRAYTDGIPVEYEPPTGPP
                     ERGTADALIRKAPYLFGPDVTEVLVQHADHVYRFDYRPMIAEHRASGAALTVSYQRIDR
                     RYVHLFGMVEFDDRNRLVSFVEKPAEPTSDLVFAAFCVFDAAVLHRYLELLDGTDWQHD
                     ISRDVIPAMLAAGEHIRGCPVPGYWADIGTVERYHEAHLSLVGTPPSLAVDAMPWTVAP
                     RTARALVTSADGVRHSVVPADLVNHGTVERSVLFPAARIGPGATVRDSVLLPGAVVPAG
                     AEIDGAVVLEDGTVQQVTTGARR"
     gene            12795..13382
                     /gene="acbP"
                     /locus_tag="ACPL_3671"
     CDS             12795..13382
                     /gene="acbP"
                     /locus_tag="ACPL_3671"
                     /EC_number="3.6.1.13"
                     /codon_start=1
                     /transl_table=11
                     /product="STP|NUDIX"
                     /protein_id="AEV84566.1"
                     /translation="MTGAVRAVRSREVYRNPWMSVREDDIVHADGSPGSYGVVTKPDYA
                     LIIPRDNGLLHLVEQYRYPVGGRFWEFPQGSWPADAAGGAADLLARTELAEETGLRAGR
                     LTPLGRIHVAYGYASQGCHVFLAEQLTAGRSQRERTESDMRQRAVDAAGWADLVGSGRI
                     TDAATLAAYTLLRMYDSGTRQPMPEGAESCTW"
     gene            13370..15574
                     /gene="acbI"
                     /locus_tag="ACPL_3672"
     CDS             13370..15574
                     /gene="acbI"
                     /locus_tag="ACPL_3672"
                     /EC_number="2.4.1.-"
                     /codon_start=1
                     /transl_table=11
                     /product="GT5|GT0"
                     /protein_id="AEV84567.1"
                     /translation="MHVVSFAFEALAFDVGMMRGGLAPLAWELARHYAAQGHRSSIVTP
                     AHGRLPYLAERYDLVELDYRDEHVVPVVPDPDVWAGQPRELGLPLVTRAHLLRHEGVDI
                     YLLSDEYLDLLPERLYPAGTSEGSDLAYFKPLVFQVGGLRFLQSRLAGDEPAVVQAYEP
                     YYHYLLPPVLAGDPRFRVMSTVASSMPIDLGVYRPQVDRLLEHFGAGTDLDRYVESPVA
                     AGADHPAATREAALGAAMAGYLPTTRLSSGRRRADYVGLFALITDHCDTVDFLTPGQRR
                     FYSTFRDTPYEAAFRRTAVARVVRENAAKQFVGGCALPENWLRRDPAEVDRAAYLSGLG
                     LDPALPTFYHVGRYSPHHKGQVELFRAVERILATDTRVNFVLRCATSAGGGGARIGDPA
                     FQAVADRHPGQVRLFWTMADEDELFTEAVAADFGLFPSKYELDTFLTAQGQLCACGAVP
                     IGTAQESTRHYRHQLATDHPLATGFALPRSFTPDDERLTGALVRTMREALRMYRDEPGE
                     YRRLAGNAAELARTFRYAEVSRRRLAHFAKLLDGTPTAADPEHVIGCGWFDQLDAAQWA
                     AHLPQIRREAIRLGDLETLRRCGPVDPGALGALYEAAYRRADFDRCVRVAELLGDRGSE
                     AVSLRRRCRVRPHEQGWEIQYRAPGAEQVALVVGGTAHRMHGSAGRFSTVLPTVPMPSP
                     VFLLTLASGRYAWDAPPATAHLADLAGQPHPAQPVGAGGR"
     gene            15576..16427
                     /gene="acbJ"
                     /locus_tag="ACPL_3673"
     CDS             15576..16427
                     /gene="acbJ"
                     /locus_tag="ACPL_3673"
                     /EC_number="3.6.1.-"
                     /codon_start=1
                     /transl_table=11
                     /product="putative hydrolase"
                     /protein_id="AEV84568.1"
                     /translation="MDGIGTTPPRDHRVVATDLDGTLLRSDLTVSARTRAALRDARAAG
                     MIHLAVTGRPVIDTRRLLAGLGYTGPAVCGQGAQVYDFGTDRLLLSRSLDTDLVRELVR
                     RIAQRTGPLALAAVSAGLGTEFLVTAGFGAPYQQHRWQLVDEPDLWRAPVAKVLIRHPD
                     HDDDTLAALADEVCGAALSVMHAGPGLVELLPGDTSKRTGLAFLAAELGFTGADTIAFG
                     DMPNDLPMFDWAGYGVAMANGHPRLRDRADEITVSNDADGVAVVLERLPAVRAGNRKAS
                     LR"
     gene            16424..18520
                     /gene="acbQ"
                     /locus_tag="ACPL_3674"
     CDS             16424..18520
                     /gene="acbQ"
                     /locus_tag="ACPL_3674"
                     /EC_number="2.4.1.25"
                     /codon_start=1
                     /transl_table=11
                     /product="GH77"
                     /protein_id="AEV84569.1"
                     /translation="MTTTTDAALIELAGRYGVSVDWTTDRGEPRTVPADTIQRILAVLG
                     VDASSGPAIAAALRAADDDARHRLLPSCVVVRQGEPARGVHPVAGAAYVVATEDGGRHE
                     TADPRNDLGRLPIGYHTLRVRVGDRSAAAPVIVAPAVLGTPDRRHWGMLAQIYSVLSER
                     SWGMGDLGDLADLTRWSARLGASFVLVNPMHAYVPDRLADPTPYRPGSRRFADPMYLRL
                     ADVAEYATAEPAVRAELDRAARQGHELTAEVLHRNALIDRARVWPVKRNALERLYRAPR
                     TAGRSAALAAFTAREGRGLEDYATWCALAEVYGTRWRSWPAALQSPHGPAVAAARRELV
                     DRIDFHRWLAWLVDEQMAAAQAAAVGSGMAIGVIHDLAVGVDPEGADAWAVQDHLAGGV
                     TVGCPADDFNPLGQDWGLPPWRPDTLAEAGYRPFADVIRGTLRHSGALRLDHILGLFRL
                     WWIPAGSGARDGAYVRYDHEAMLGVLAVEAFRAGAMIIGEDLGTVHPAVRAELADRGIL
                     GTSVLRFEYQGGSENRSGPLPADQWRAGCLATLTTHDLPSTAAWLSGEHVDLQDRLGLL
                     NRPRAEVAADAAAERDGWLAELRRTGLLEHETAVPGMSAESLALHRFLARTPARLVGVW
                     LPDLVGDRRPQNLPGTSTEFPNWQLPVADADGRPVAMDDLASSAGAQAVAGLYAASAEP
                     ATTP"
     gene            18552..19451
                     /gene="acbK"
                     /locus_tag="ACPL_3675"
     CDS             18552..19451
                     /gene="acbK"
                     /locus_tag="ACPL_3675"
                     /codon_start=1
                     /transl_table=11
                     /product="STP|PfkB,STP|PfkB"
                     /protein_id="AEV84570.1"
                     /translation="MSEHTDVLVLGGAGVDTIAYVPELPLPFQDSYVVAAIEPRAGQTG
                     DNVALGLHTLGLRTMHVDVLGDDPEGDLVRAFHTRHGLPFAALPTAAGTKRAVNLVGPD
                     GRRLSLWDGSREAEEDRYPAALIAAHTAHARHVHVCITPPGQHVFGQLNDLPVTVSTDL
                     HNWDGAYEGFEVYAFNADLVFLSATALTDVAATMRRVIDRGRARLVVATDGAHGGSVLV
                     RGETEVRRYAAVAPEAPVVDSNGAGDAFVSGFLFGHLAGEPLETCLRYGAIAGAYACTI
                     PATRAGAIDRAALLRPAA"
     gene            19448..20527
                     /gene="acbM"
                     /locus_tag="ACPL_3676"
     CDS             19448..20527
                     /gene="acbM"
                     /locus_tag="ACPL_3676"
                     /EC_number="2.7.1.-"
                     /codon_start=1
                     /transl_table=11
                     /product="2-epi-5-epi-valiolone 7-kinase"
                     /protein_id="AEV84571.1"
                     /translation="MKRPPHHPVTVADVGGTHLRWARWSPDGGLGEVHTTPSPGHARRP
                     GAGAADLQAELIRELASRVEPGARAGVSLGAAMDHHSGTAYASAPLWGPQVSPFDVPAA
                     LRAARPDVHWTVVNDVTAGLLHLAEMVRDAGVRKACLVTISTGIACRTMDLRTGGIPVD
                     AAGLQGEIGHLPATVLADGVPVVTRCDCGEPGHVAASSSGPGIRRVAAVLARRDPATWA
                     GSGPTTRMMAGSGFEDAFRAALDDGDPVAADLLTAVTAPIADLLRTALCLDPELDLIAL
                     TGGVAHGLEPHYSAAVHDHLRRRGLYLTSEREPDWLTGRIRVVPPATADPLVGAGLAAL
                     AAGPVPAYSGGGREALVGR"
     gene            20524..21624
                     /gene="acbL"
                     /locus_tag="ACPL_3677"
     CDS             20524..21624
                     /gene="acbL"
                     /locus_tag="ACPL_3677"
                     /EC_number="1.1.1.-"
                     /codon_start=1
                     /transl_table=11
                     /product="cyclitol dehydrogenase"
                     /protein_id="AEV84572.1"
                     /translation="MSRHRAIVRTGTGVVVADVPTPVPGPGELLVGTEWAGLCGTDIQM
                     LRGLRDDPEPIIGHEGIARVIAAGDGVPGTLRPGTLVAVNPTHRDDPSFLLGHNVPGLL
                     QERTLLPATAVSGGLVLPLPDGTDVTLGPLLEPLAVVSYALSQLGAVRPATLVIVGDGT
                     VGHLAARAAVTWLAERPRVVLVHHTAAGRDFSAAGPHPADVLLTTGELAGRPLPGPVAA
                     LLATPRDATVEALEAVLAAAGADVLIDVLGGLPPGARSAMLPGVDLTAVRAANCGGFPE
                     PALVTTTSGGTRLFGHRGVGNAHLRAAAGELARDPDRYRDLVTHRSDLAGAARIMTALR
                     SGRDRIIDGRRLVKLAIQVNVREDHR"
     gene            21621..22376
                     /gene="acbN"
                     /locus_tag="ACPL_3678"
     CDS             21621..22376
                     /gene="acbN"
                     /locus_tag="ACPL_3678"
                     /EC_number="1.1.1.-"
                     /codon_start=1
                     /transl_table=11
                     /product="cyclitol oxidoreductase"
                     /protein_id="AEV84573.1"
                     /translation="MSGTLVGRRALVVGGTTGIGRGIADAWAAAGAEVTVCGRSEPAGD
                     GAAGLHWEPLDLTRTGEAGARLERIAGDRVDLACFAAVSYGARRAVFEDVAVDEWRTQL
                     DINVHGLWLTLRAALPGLRAARPGLFVGVSSEVVYNAGPGRSGYTASKAAAKALLESVA
                     QEEDESRVRIVQVLPAGMVDTPSIRRRRPAGFDYSDYMVPADFARNALELAATAGAGHH
                     GDSLVVDRGGDWWSVRERMPVSQSRPVRT"
     gene            22373..23185
                     /gene="acbO"
                     /locus_tag="ACPL_3679"
     CDS             22373..23185
                     /gene="acbO"
                     /locus_tag="ACPL_3679"
                     /codon_start=1
                     /transl_table=11
                     /product="2-epi-5-epi-valiolone-7-phosphate 2-epimerase"
                     /protein_id="AEV84574.1"
                     /translation="MTCRVGLTEWRLAPSGAAAIRLAAAVGADGIQLDFGGPGRGVLVD
                     GPGRAGQLRAVADEAGVDLLALAGNLLNDIGLTSQPAVVQPVLARLADTATELGVPLLI
                     VPSFRRSAITDAMSFTRTAAALRWAVSLAEARGIVLASENVLPPARARQLVEEVGSPAF
                     RLLLDTFNPVRYGLDPAWLATELRPWWADQIHLKDGPPDTGPSPLLGAGQGGVRRTLTA
                     LRGSPAPVRALVLENDYRDGHGARLRADLEWARRAAVNARESEKGKLT"
     gene            23182..24378
                     /gene="acbC"
                     /locus_tag="ACPL_3680"
     CDS             23182..24378
                     /gene="acbC"
                     /locus_tag="ACPL_3680"
                     /EC_number="4.2.3.4"
                     /codon_start=1
                     /transl_table=11
                     /product="2-epi-5-epi-valiolone synthase"
                     /protein_id="AEV84575.1"
                     /translation="MSGVETVGVHADAHRDSWQVRAQKQITYEVRFRDDVFGLDSTDLL
                     EAGADGAGSRRRFVVVDSAVDALYGSRIREYFTHHGIDHSILVMRVGETVKDFDTAGRI
                     VAAMDAFGLARRREPMIVVGGGVLMDVAGLVASLYRRGTPFLRVPTTLVGLIDAGVGAK
                     TGVNFNGHKNRLGTYAPADLTLLDRRFLATLDRRHLSNGLAEMLKIALIKDAELFQLLE
                     RHGRVLIEERFQGRTGTGDRAAVRALRAATHGMLEELGPNLWESRLERSVDYGHTFSPT
                     IEMRALPALLHGEAVCVDMALTTVLAYRRGLLDVAQRDRIFAVMTALGLPTWHPLLTPE
                     VLEAALQDTVRHRDGWQRLPLPVGIGGVTFVNDVTAAELQAAALMQHRLAEDALLLRA"
     gene            complement(24439..25401)
                     /gene="acbB"
                     /locus_tag="ACPL_3681"
     CDS             complement(24439..25401)
                     /gene="acbB"
                     /locus_tag="ACPL_3681"
                     /EC_number="4.2.1.46"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="AEV84576.1"
                     /translation="MKILVTGGAGFIGSHFVTSLISGDIATPQPVTQVTVVDKLGYGGN
                     LRNLAEASADPRFSFVRGDICDEGLIEGLMARHDTVAHFAAETHVDRSVVASGPFVASN
                     LVGTQVLLDAALRHHIGRFLHVSTDEVYGSIDTGSWAEGHPLAPNSPYAASKAGSDLLA
                     LAYHQTHGMDVVVTRCSNNYGPRQFPEKMIPLFVTRLLDGLDVPVYGDGRNIRDWLHVS
                     DHCRGLALALGAGRAGEVYHIGGGWEATNLELTEILLEACGAPASRISFVTDRKGHDRR
                     YSLDYSKIAGELGYRPRVDFTDGIAETVAWYRANRSWWT"
     gene            25559..26395
                     /gene="acbA"
                     /locus_tag="ACPL_3682"
     CDS             25559..26395
                     /gene="acbA"
                     /locus_tag="ACPL_3682"
                     /EC_number="2.7.7.24"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase"
                     /protein_id="AEV84577.1"
                     /translation="MPVYDKPMIYYPLATLVSCGIREILVITTETEAAQFQRLLGDGSQ
                     WGLRLEFAVQQRPGGIAEAFLIGEEFLAGGPVALMLGDNLLHGVDFRPCVQRARETAGG
                     HVFGVAVADPSAYGVVEFDAAGRVLSIEEKPVRPRSPYAVPGFYLYDADVVETARSLRP
                     SARGELEITEVNQAYLRRGALSVTLLGRGAVWLDTGTLADCMRAVDYVRAIDEGQGIKI
                     GCVEEAAWRAGFLDTAQLRALAEPLMSSGYGQYLLALTGDGLSRTPQWPALTAAAG"
     gene            complement(26488..29589)
                     /gene="acbE"
                     /locus_tag="ACPL_3683"
     CDS             complement(26488..29589)
                     /gene="acbE"
                     /locus_tag="ACPL_3683"
                     /EC_number="3.2.1.1"
                     /codon_start=1
                     /transl_table=11
                     /product="GH13_13|CBM41"
                     /protein_id="AEV84578.1"
                     /translation="MDERLKSHIVRALLPVLVGAAGGLPAPRAAQAESPPDRPSHAEQL
                     YLVMPDRFANGDTGNDQGGLTGDRLTTGYDPTDAGFYHGGDIQGVIDKLDYIQGLGTTA
                     IWLTPIFKNKPVQGTGPNASAGYHGYWITDFTQVDPHFGTNEDLKRLVGLAHRRGMKIY
                     LDIVVNHTADVIKNAEGTAYADKGTAPYRDTAGRPFEDRNYADGTHGFPKVDEKSFPHR
                     PFFEKPSDATAKAPAWLNDPTMYHNRGETTFGGENAEYGDFTGGLDDLWTERPEVLHGL
                     TDIYAGWIRRFGVDGYRLDTLKATDLAFWRPFAEGVGKAADKAGKRDFFLFGEAWSKDQ
                     EVTSTFVRRGGLPATLDFPFQGAAQSYVTGKAPASSLAGLYAKDDLYTAAGTDAGRLPT
                     FLGNHDMGRIATLIKAGSDPNGLRRLELANELMFLTRGQPVVYSGDEQGFTGALGDKGS
                     RQDMFASRTPDYLDDRLIGTDKTHASDNHDTGHPLYRTIAELGALRKAHPALRDGEQIT
                     RYAADRAGVFAASRIDRDQRAEYVIAVNNATTAQTVTFDTYTPGSGFQPLYGTGETAAT
                     GADGRLTITVPALSAVAYRAEKPIPAADGAPAVTITAPAAGTLVPGRTELTAAVTGDPL
                     STVTFSARAGNGPWQPIGTAGRAPYRVFHDLTGLAGGAEVQYRAVARDGRGRTATTTSR
                     IRVGTVRAEAGYAVVHYQRPAGDYDGWRLHATGDVDAAALDPQGEPFTGTDAYGRFAWV
                     KLRPGATKVTFTVSDANGVKDVDADRSLNPQQTPGIWLHQGDPAISYQGPAPAPAPNTA
                     ILHYRRPAGDYTGWGLHLWDGAATPTADWGAPLLPESFDSFGAVFRIPLAAGATGLSYI
                     MHAGEAKDLPTDQRLEFADAGREVWVQAGVQERLLPSVVKPAKLDLTRADAVRVDRDTI
                     AWQTGTPDTLEPAGAATDGRVYDLVHAPNGGLRLVDGDLAGDYRSIRLTAQRDGLTEKQ
                     RRQAPELWQYPAFQAAAALPSGDGQFYVTERDAQGRLMSVTGVR"
     gene            29915..32089
                     /gene="acbD"
                     /locus_tag="ACPL_3684"
     CDS             29915..32089
                     /gene="acbD"
                     /locus_tag="ACPL_3684"
                     /EC_number="2.4.1.19"
                     /codon_start=1
                     /transl_table=11
                     /product="CBM20|GH13_2"
                     /protein_id="AEV84579.1"
                     /translation="MQRHARHAIAAAVAVSLLPPSLPAHAAGASAVVPYAGNPASLKQD
                     LCYQIATDRFSDGNPANNNPGNVPGMFADKTKLNDRQEWLKYMGGDFAGITQRMEYLKN
                     LGVGAIWISPHVDNINVPANGATGYHGYWPRDFKRLEEHFGTDEEFDALVSAAHASNIK
                     VIMDWTPNGTNPPNQAEDGALYDDGQLVGRYGADSAGHFHHGPAIGDFNDRYQDQYYSL
                     ADIADLDQQNPRVDQLLKDDANYWMDRGVDGIRVDAVKHMPLSWQRSFADAVTSHKSAA
                     IFGEWYMGDQSDPLYADQVKFANTSGIAAMDFYTNRSIRDTFAGAGSMKSLDAAITKTN
                     RDYLYEQDLITFLDNQDTRRFGTLNSDPAALHRALAFLLTTRGTPCLFYGTEQYLHNDT
                     GEGSNKGKDPYNRPPMASFDTDTVAYREIRALSDLRRSNPAVAYGDHQQRWINDDVYVY
                     ERRFGDNVLLTAINKGSHEYRLDGLRTALPAGTYRDVLGGTFGGSDLTVEDGDGTDRST
                     VAPVLGAGQVAVWSYRAPVDTEPRIGGVGPVVTRAGATVTVEGTGFGSGGTVAIGGVPA
                     TVQQWTADRITATVPVGVPTGAVQVTVGNGSGTSNGYPITTRTGKPVPVQFTVQNPPAT
                     APGESLYLTGDVAELGHWSTSPDQTAGQLLRVPNESRGVLVADLPAGAPVEFKFVKVAA
                     DGTVTWEGGANHRYTVPAGGTGTTTLTWQR"
ORIGIN
        1 ttggttctgt cccgtcatcg cgacgtcatg cgtcgcctgt ccgccgtgct ggcgctcggc
       61 ctggtggtgc ccctgctgct ggcgccaccg tggcgggcgt cggccgcgcc ggccggcgcg
      121 gccgagccga gcgccgcggc cctggcccat tggggagccg accggccggc acccgccgaa
      181 cagttctact tcgtcctgcc cgaccggttc gccgacggga acccgaagaa cgacaccggc
      241 ggtctctccg gcgaccggct ctccaccggg tacgacccca ccgacaaggg cttctaccac
      301 ggtggggaca tccagggggt gatcgacaag ctggactaca tccaggggct cggcaccacc
      361 gccatctggc tggccccggt cttcaagaat cggccggtgc aggggaccgg cgccgccgcc
      421 tcggccggct accacggtta ctgggtcacc gacttcaccc aggtcgaccc gcacttcggc
      481 accaacgccg acctcaagcg cctggtgcag ctggcacacc ggcggggcct gaagatctac
      541 ctggacatca tcgtcaacca caccgccgac gtcatccaga acgagggcgg caagagcacg
      601 tacgtggaca aggccgacgc cccgtaccgg gacagccggg gccggccgtt cgaggaccac
      661 aactacgccg acggctcgcg gccgttcccg aaggtgaacc tgcagtcgtt cccgtacacg
      721 ccggtcttcg ccagccccgc cgacgccacg gcgaaggtcc cggcctggct gaacgacccg
      781 accatgtacc acaaccgcgg caattcgctg ttcagtgggg agaacagcga gtacggcgac
      841 cacaccggcc tcgacgacct gtggaccgag cggcccgaag tggtccgcgg catgaccgag
      901 atctacgccg actggatccg ggacgccgac atcgacggct accggatgga caccgtcaag
      961 cacagcaaca tcgagttctg gcagcagttc aacccggcca tccagcaggc cgcgcgacgg
     1021 gccggcaaac ccggcttctt catgttcggc gaggtcttca gcgccgacca ggaggtggag
     1081 agccgatacg tccggcaggg cggcctggcc gcgtccctgg acttctcctt ccagtcggcg
     1141 gcccgcacgt tcgtctccgg tgacacgccg gccaccgcgc tggccgacct ttaccgacac
     1201 gacgacctct acaccgcccg cgacaccggg gccggccgga tgcccacctt cctcggcaac
     1261 cacgacatcg gccggatcgg ctcgttcatc accaccggcg gcgccgaccg gaccagttac
     1321 ctgcggcgcg accagctggc ccacgagctg atgttcctca cccgcgggca gccggtggtc
     1381 tactccggcg acgagcaggg cttcaccggg ccgggcgggg acaaagacgc ccggcaggac
     1441 atgttcgcca gccggacgcc ggactacctc gacgacgacc tgatcggcac cgaccggacc
     1501 cacgcgagcg acaactacga caccgggcac ccgctctacc gcaccatcgc cgagctgggc
     1561 gcgctgcgta aggcgaaccc ggcgctacgc gacggcgtgc agatcacccg gtacgcggcg
     1621 cccggcgccg gcatcttcgc gttctcccgg gtcgacccgg tccgacgcca ggaatacctg
     1681 gtcgcggtca acaacgccac caccgcacag acggccaccg tcggcaccgc cacgccgggc
     1741 agcaccttca ccggcgtcta ccgcgcgggc ggtaccgccg ccaccggctc cgacggcaag
     1801 ctcacggtga ccgtgcccgc cctgtccgcg gtggtctacc ggggcggcag ccccatcgcg
     1861 gtcccgtcgg cccggcccac cgtgcggatc agcgcaccgg ccgcgggggc gtccgtgccg
     1921 tcgcgggccg atctggtcgc cgacgtcacc ggcgatccgc tggccacggt gaccttcgcg
     1981 gcgcaggccg gatccggccc gtggaccgtg atcggcaccg cgcggcaggc cccgtaccag
     2041 gttcaccacg acctgaccgg tctggccggc ggggtcaccg tgaggtacaa ggcggtggtc
     2101 cgggacggtc gcggacgtac cgcgagctcc acctcgtcgc tgcgggtcgg caccccggac
     2161 acccacgtcg cgccggagcg gatggtggtg cactaccagc ggcccgccgg tgactacggc
     2221 gcctggcggt tgtacgcctt cggcgacatc gacgcgtccg cccagaccac ctacccggac
     2281 gggcagccgt tcgccggcca ggacgagtac ggcgcgttcg cctgggtgag actcaagccc
     2341 ggcgccaaga acgccggttt cgtcgtggtg gacggcaacg gcgtcaagga cgtccagcag
     2401 gaccggttcg tcgacccggg ccgacaaccg gagatctggc tgaaagcggg cgacgcgacg
     2461 gtgtacccgt cccggcagga cgccaccggc cggcccgacc cgcaaccgga cccgaagacc
     2521 gccgtcctgc actaccggcg cgccgacggc gactacaccg gatggggcct gcacgtctgg
     2581 gacggcgcgg cccagcccac cgagtggacg gcgccgctgg ccccgtccgg gcgcgacgcc
     2641 tacggtgtca cgttccgggt gccgctcgcc gacggcgcca ctggggtcag ctacgtcctg
     2701 cacgccggtg acaccaagga ccagccgacc gatcagcgga tcgacttcgc cgccggccgt
     2761 gaggtgtggc tgctcgacgg ggtggccgag cgcctgctgc cggtgacccg ccggaccgcg
     2821 gccggcgccg ggatcgatgt gacgacctcg cgcgccgggt gggccagccg ggacacggtg
     2881 gtctggaaca ccggtgtggg cagcaccttg cagccggtcg gcggtggcac cgacgggcgg
     2941 gtgtacgagc tggcctacgc cccggtcggg gggatcaccg tggtcggcgg ggagctggcg
     3001 ggggcgtacc ggaccctgcg gctcaccgcg cagcgtgacg gcctgaccga gagccagcga
     3061 gtccggttcc cgaagctgtg gcggtacggc gccttccgcg tcgccgacgc cgaccggcac
     3121 cgtctcgcca cggcgttgcg cggtcaggtg gtgatcaccg aacgggacgc ctcgggcaag
     3181 ctgctcgcgg ccaccggtgt gggcgccgcc ggtgacctca ccggctgacc ggagaccggg
     3241 atgatcgggg cgcccgcgcc gagcgcgcgg gcccccgatc gcggtgaacc ggtcagctgc
     3301 cgggcatctc gtagcgccgc agcccgagcc ggaaggtgcc gtaccccagc aggacggtga
     3361 gcgtggtgac cggcagcatc cacagcagcg gcccggcgtc cccggtgagc aggtagcgca
     3421 ccggtaggta ggcggtgaac gcgaacggca gcacccaggt gagcaccccg cgcagcaccg
     3481 ggtggtagag gttgagcggg tacgcggtga actcgctgag ctggttgacc gccaccatca
     3541 cgttgaggct gctggtcatc cagaacgaca gggaggccag gaacgccttg aggaaggtgt
     3601 ggatcagggc gccgccgagg accaggggca gcaacagcag ccactgtgcc acggtcaggt
     3661 gcaggtccat cgtcccggcc gcggtgacca cgatggcgat gccggtggcc agctccccga
     3721 acccgtccgg atagaggaac cgttcggaca gcagcgcgta gaacgggttc accggccgga
     3781 tcaggtagcg gaagaagtcg ccggtgcgca ccagctgcca ggccaggatc cacagctggt
     3841 cggtgaagag ccggtccagc ccgcggggca gcagggagaa cccgagcagg aacagcgcct
     3901 gctggcgggt ccagccgccg agcgccggaa cgtactggaa gatcaccccg atcagggcga
     3961 tctggcaggc gatccggatg acgaagctgg ccgccccgat gaggaagtcc atccggtacg
     4021 cggtgagccg gtgcaggctc gccccgcaca gcaccgccgt gaggcgcagg taccggcgcg
     4081 ccgtggagac ggtcatccgc cgagcacctc caccctgcgc agcgaccggt tccaggccag
     4141 ggccagcacg ccgtacagca gtaccgccca gagcgcctgg acaccgagga tggcagcggc
     4201 gccggaaccg ccggagtagc cgccgagcag cagccgcaac gggctgtcga tcaggccctg
     4261 gaacggcagc agccgcagca gccgggccac gccgtccggg aacagcgcga gcgggacgac
     4321 ctggccggcc aggaaggcga cgagcgcgtt cttgatcgta cggatgcccc aggtgttggt
     4381 cgtgacgaag gcggcgagac ccaccaggaa gttgatctcg aaggcgagga tcaccgagag
     4441 cagcagcgcg acggcgaaca gcagcaggtt ggcgggcggg ggagcgggca gcgacgcgaa
     4501 catcgcgaaa ccggcgagca ccggggcgcc ggccagcagc gcactgagcg cggcggtcgg
     4561 caggttcacc gccagacagc tgagcgcgta gttcgccggg cgtaccaggg agaccgcgat
     4621 gtccccgcgg tacacctcgc cggcgatcat ctcgtcgatc cggttggtgt gcagcatccc
     4681 gagcacctgc gcgagcacga tgtacgaggt gagctgtgcg aacgggaggc cggccggtgc
     4741 cggtccgccg gcgtagacgg ctcgccacag gaacacctgc aacgaggtgg ccgcagccgc
     4801 cgtgagtgcg ctcaggacga tggtcgagcg gtaacgggtg acggcgtgca gtccggcgag
     4861 ggcgaacggc gcgtaccggc gcgcggcgcg gatcatgcgc cgtccccggc ggtgaccggc
     4921 tccgggcgcg acccggcgta gatgcggcgc agcagtgtct ccagatcggc gtccggcacc
     4981 agcacgtcgc tcaggtcgaa ccggtccagc aggaaggcga tcacctgccg ggccgaccag
     5041 cggtccaccg ggaactcgac ccggatccgg ccggactcgg ccggagtggc gtccacctcg
     5101 ggcagtcctt cggtgatgat gcgcagcgcg gcggcctcgg agacgctgcc ggcggcgtac
     5161 tcgaaggtga ccgcccgggt gtccaccgac cgcagcaggt cccgcatcgt tccctggtgg
     5221 acgatcgtcc cgcggtccac gaccagcgcc tgatcgcaga tgctggtgat gtcgccgatg
     5281 tcgtggctgg tcagcatgac cgtggtgccc agttcggcgt ggatgtggtt gatcaggtcc
     5341 cggaccgcct gcttgaggac caggtccagg ccgatggtgg gttcgtcgag gaagaccacg
     5401 gccgggtcgt gcagcagcga ggcggcgatc tcggcccgca tgcgctggcc caggctcagc
     5461 tggcggaccg gggtgttgcc gagggcgccg aggtccagcc ggtcccggaa caggcgcatg
     5521 ttccggtcgt acaccgcctg cggcacctcg tagacgtgcc gcaggatgcg gaacgagtcg
     5581 aggaccggca gatcccacca gagctggctg cgctggccga agaccacgcc gatccggccg
     5641 gcgacccggg tgcgctgccg gtgcgggtcg aggccgtcga cccggacccg cccggtggtc
     5701 gggcgcatga tgccggtcag gagtttgatc gtggtggact tgcccgcgcc gttcgccccg
     5761 atgtaggcga tcttgacacc ggacgggacc tcgaagctga tgtcgtcgac ggcccggacc
     5821 acgtcgtacc gggccgagaa catggttcgc aggctgcccc gcagacccgg ctcgcgccgg
     5881 tagcgcttga agtgcttgct gaggtgctcg gcgacgatca tgccggtcgt gccgtccggc
     5941 cgggcatgcc gggcgtaccc gggcatggcg agtcgagatg attcacggat cctcgtttct
     6001 tttccggaag atgtcgtggc ggcaacattt tgaaattgat gattaccatc aattaaccga
     6061 gtttccacaa tgtcgcgccg gtctcggcga ccggctatat ggaagcaatc cgaacagtcg
     6121 gccggaggat gttgtcgacg gtgtgacaat ccgcgggcgg ccggcgccgc gctgcgccgg
     6181 agtgcggccg gccatcctcg ttgtccgagg tgctgagggg cacggccgat cgctcggtag
     6241 ggggagggcg gtcatccgct gtgcggtgcg ggatcagcca agtgagcatt gaatgcgatt
     6301 gcggcggcac tcgtcaagcc gccgtgcccg gtcctcgaaa tgtgaccgcg aaacctttcc
     6361 cgtccgatat ggagtgaccg gcgtcataat ttgttgtttc gggcaacaaa cccatcgccg
     6421 atcctcgata tattaccagc cggcttttcc gacattcggc cagatgaatg cggttacaga
     6481 cgggaccggc gggtggggcc ggatggtggg cggggttgcg gaggggcggc cggtgaacga
     6541 tgcaagaact tgctgaaact ttcaggtcca gttgcggtgc cggtttcacc gccatagatt
     6601 tcgcggtcat cgggcctcga cggttccgat ccggcccggc tgagtgtgcg gctcgctggg
     6661 cggtgcagcg acgccgacgt cgcttgaacc ccgaacttcc agcccatctc accggatgcg
     6721 gcggctatcc ccttcaggag tgacccgtga tgtgttccga gccggttcgt ttcgacaccg
     6781 gcgccgcgac ccggcggcgg ttccggtgag caggcaggcc gacctgctcg cccgggagtc
     6841 gcgtcacctg gctccgggag cctccgaaga ggcggcgctc ggccggcggg tgttcgtcga
     6901 gggccgcggc gcgaccctgc gcgacgccga cggtgtggaa tacctcgact tcgccgccgg
     6961 tactttgacc cagtcactcg ggcactgcca ccccgaggtg gtggcccggc tcaccgaaca
     7021 ggccgggaag ctgtggaacg tccacgactt cgcgaccgcc gaccgcgccg cgctctgcga
     7081 actgctcgcc gaactgctgc ccgaccacct caccacgctc gccttcttct cgaccggcgc
     7141 cgaggtggtg gaggcggcac tgcggacggt ccaggccgtc gccgaacccg gccgcaaccg
     7201 ggtcggggca ctgcggcacg gcttccacgg caagacgatg ggcgcccgca tgctggtgca
     7261 ctgggacgtg ggggaccagt cgttcgccgg caacagcgtg ctggggtacg ccccgtactg
     7321 ctaccggtgc ccgctggagc tgagctatcc gtcgtgcgag gtccgatgcg ccaccctggt
     7381 acgccggcac atcgccgaga aacccaacgt gagcgccctg ttcttcgaac cggtgctggg
     7441 cgcggccggc gtgatcgtgc cgccaccggg ctactgggag cagatcgcgg ccgcgtgccg
     7501 ggacaacggc gtactgctgg tcgccgacga ggtgctcacc ggcggcggcc ggaccggaac
     7561 ctttctggcc agcgaggcga tcggggtcgc cccggatctg gtcacgttgg ccaagggcac
     7621 cgcgtccggt ttcccgttcg ccgtgctcgc cgggcgtgac gaggtgctgc ggcatccccg
     7681 ggccgggctc gccggatcga ccgcctccac ctacgccggc aacccgctcg ggatcgccgc
     7741 cgcccacgcc accctctcgg tgatctcccg cgaccggctg atcgagcagg tccgggacct
     7801 cggcgcggtg ctggccgacc gcctggccga gatgcacgac cggcacccgc acctgggcga
     7861 cgtgcgcggc atcggcctgc tgcacgggct cgagttcgtg cacgaccggc agagccggcg
     7921 gccggccccg gagatcgccc ggcgggtcta caccaccgcc ctcgacgccg gtctgcgcac
     7981 cgccatcggc gggcacatca tccggctcgc gccgccgttc gtcatcgacg agaccgagct
     8041 gctgcgcggc ctggacctgc tggaccgggc gattaccgag gccgggcggg tgacggcatg
     8101 acaccccggc cggtcagcac gatcgacgtg agcctcgcca gcctgctgcg caccgccgac
     8161 tggccgcacg aggatctgcg cggtcccggc ggggtgcgga tcctcgacga ggcgatcctc
     8221 ggcccgtccc ggttgctgat cgtcgcggcc gaacggaacc ccgagagccg ctacttcgtc
     8281 gccgttctgc gccacgatcc gtcccgggag gccgtcggcg acgccgccca cgaccgggcc
     8341 gtggtccagg cgatgcgcga gcggctggca ctacccaccg cagccggcca tctgatcgtc
     8401 ttcgacggtg accccgcgcc gttccgagcc acccggccgt tcgaccccgg gtggtcgacc
     8461 aacgccctgt cgctggccga tctggacggg acactgcaca tccacaaggc gtaccggctg
     8521 gtgtcggccg ccacccggga accgcatctg ctgcggctga tgcatcgcgg cggccgtacc
     8581 cagcgatggg ccggcgacta ccactacgtg gagcagccct ccgggcgccg ctacccgctg
     8641 ggcctgctct acgcctatgc cgaaggcgac agcctcgacc tgccgctgcg gcacagcatc
     8701 cggtcgatgt ggccggcgct gctgggcggc accgaaccgg ccggcgcggt gacggccgcg
     8761 cagcggtcca tcgcgggcga gctgcccggc gtcggccggt tcctccgcga cttccatacc
     8821 gaactggcgc agcggctgga acccgcgccg acgttcccgg tgaacgccta cctgcgggag
     8881 accgccgagc gggtggcggc gctggggtgc cggatcagcg ccgacgaacg ttacccccgg
     8941 ccggtgcgcg aggcggtcgt cgccgccctg accggcgaac tggaccaggc caccaccagc
     9001 gcggtgcggg tgccgtggcc ggccggcccg tcgcacggcg acctgcacct gtcgcacatc
     9061 ctgcgccggc agacaccgga cggctggcgg ctgtgtgtga tcgacctgtc cacgcccgcc
     9121 cccgacccgg ccgacccgct cggcgccgcc cagtcaccgt ggcaggacct ggtggcgctg
     9181 ctgcgcgggc tggagatctt caccgccgac gagttcgtgc accaggcggc cctgcggctc
     9241 ggcgccgacc aggacgacac ctgccggacc gtgctgctga tcagtgccgg gcagaccccg
     9301 gacacgccgg gttggaccgg gtcccggctc accgcgctgc ggcggatgca cgacgcggcg
     9361 tcggtgtggg ccggacaggt ccgccggatg ctgctgtccg gttatgccga cggcggcgag
     9421 gcggccgagg agcaccccgc ctggcggatc ttccggctcc gccgtctgtt gcacgaactg
     9481 gactacgcgt acgcccacga ccagcactac cacgcggcga tcaaccttcg acacgtcctc
     9541 cagacctacc ggccgccggt caccggggag agctgagcac atgcacatca tcgagacgta
     9601 cttcgaatgc ggcggcttcg accaccggtt catccagggc ggcacctcgg tctatctctg
     9661 gcagctgtcg cgtggcctgg ccgacctggg acaccgggtc tccatcgtca caccggcgca
     9721 cggccgcctg gacgatctgc gccggctgca cgaggtcgag gacctgcccg gcaccgacga
     9781 gtacgaactg ccgctggtgc tcgacccgcg cgtgtggggc gaacggttcc cggcccagat
     9841 ggacatcgcc ctgcggacca ccgcgcatcg gatccggctg gcgggcgtgg acctgtactt
     9901 cctctccaac gaactgctcg atcagttgcc ggaccggttc tatcccccgt acgagagcaa
     9961 gggggttgat ctggtcttct tcaagccgct cgcctatcag gtggcggcca tccggttcat
    10021 caggtcgcac ttcggtgacc agcgcgcgat cgtgcacgca cacgagccgt tctaccacta
    10081 cctgatgccg gccgccttcg ccgcggaccc ggccaaacac gtggtcagca cggtgcagag
    10141 caacatgccg atcaacaagt cggtgtaccg ggccgaggtg gcgcggctgc tcggcttcct
    10201 cggcgccccg aacgcgctgc ccgccgacga tccggccggc agccgttcgc cgcacaccgt
    10261 ggcgatgagc cagtaccagc agctgaccca cctgcactac gaatacccgc cggaccacgt
    10321 gcgggtctac gacctggtgg ccgagcacgc cgaccggatc gacttcctgt cgccggggca
    10381 ccgcgactac tacacctgct tcgccgacac cccgttcgcg cagctgttcg ccaccctgcc
    10441 ggtgtcgcgg acggtacggc gcaacgcgga caagacgttc gtcggcggct gcgccgtcgg
    10501 tgacgagtgg gtgaccggcg agctgccccc ggtcgaccgg gagaaggtgc tggccgggct
    10561 cggcctggac ccggacctgc cggccttcta ccacaacgcc cggtacgcgg tcaaccacaa
    10621 ggggcaggtc gagctgatcc gggccgtcga ccgggtgctg agcggcggcg tgcgggccag
    10681 cttcatcgtg cgctgcctca gcgacgccgg gatcgccgac ccgctcttcc acgaggtggt
    10741 ggcccgccac ccgggccggg tgaatctgga gtggcaccgg gtgccggagg accagctgcg
    10801 ggagtacgcc cgagccgcgg acttctgtct cttcccgtcc aagttcgaga tggacacctt
    10861 cctgatcgcc cagggtgagg cgatggctgc cggtgcggta ccgatcgcca ccgcccagct
    10921 ggggatggcg cacttcggtc acgtcgccga cccgctgacc gggccggacg cggcgacggc
    10981 caccggattc gccgtcaacc gctcgttcgc cgaggacgat ccgctgctgg tccagggcct
    11041 gaccgagcag atccgccggg ccgtcacgct ctggaacgag cagcccggcc agtaccgccg
    11101 gttgtccgcc aacgccgtcg cccgggcccg cgagttcacc tggcggcggg cggcccaggc
    11161 gcacgaggcc gcgttcgccg gggtgtgggc cggccgtacc ccccgcctgc cggtcggtga
    11221 cctgctgcgg ttcggctggt tcgacgagct gcccgcggac gcctggacgc tgcaccgcga
    11281 cgagatcgcg gaggtggccc tggcccacgg cgacgccgac gcctacctgc gctgccggcc
    11341 cgacgacctc gacgccctgg cggcactctt cgagcgggcc tgggcccggg ccgacttccc
    11401 ggcctgcgcg cggaccgtag agctggccga ggagcaccgg caggagcggg tgccgcagtg
    11461 gcgggcccgg ctcgccggcc gcggccgcat cgaccgcgac ggtcggctgc actaccgtcc
    11521 gccgtccgcc gaacgggtcg aactggtctt gcccgacctg gccgaacccc tgcgcggaac
    11581 ggtcaccgtg accgcgatgg ctccgaccgg cgacaccttc accggacagc tgccggccgg
    11641 aacccggcgt gccgacctgc tgctcaccct cagtgacggg cgcaccgtct gggacgaggt
    11701 gacggcatga gcacgggcgt acgggcggtg ctgctcgccg gtggtgaggg acggcggatg
    11761 ggagcgctcg gcgcgggccg gctcaagccg ctggtgccgt tcgggggcgc ggcccggctg
    11821 atcgacttca gtctggccaa tgcccgcgac tccggcctgg accaggtgct gctgctgtcg
    11881 cagtaccagg agcggcagct gatggacgac ctgcggcgca cctggtggca gccggggttc
    11941 cgggtgcact tcgggccgta cgaccgggcc tacaccgacg ggatcccggt ggagtacgag
    12001 ccgccgaccg ggccaccgga gcggggcacc gcggacgcgc tgatccgcaa ggccccctac
    12061 ctgttcgggc cggatgtcac cgaggtgctg gtgcagcacg ccgatcacgt gtaccgcttc
    12121 gactaccggc cgatgatcgc cgagcaccgc gcgtccggtg ccgcgttgac cgtgtcctac
    12181 cagcggatcg accgccggta cgtgcacctg ttcgggatgg tcgagttcga cgaccgtaac
    12241 cgtctggtct cgttcgtgga gaagcccgcc gaaccgacca gcgacctggt gttcgccgcg
    12301 ttctgcgtgt tcgacgccgc ggtgctgcac cgctacctgg aactgctgga cggcaccgac
    12361 tggcagcacg acatcagccg cgacgtcatc ccggcgatgc tggccgccgg cgagcacatc
    12421 cgcggctgcc cggtgcccgg ctactgggcc gacatcggca ccgtcgagcg ctatcacgag
    12481 gcccacctgt cgctggtggg cacaccgccg tcgctggccg tcgacgccat gccgtggacc
    12541 gtggcgcccc ggaccgcccg ggcactggtg acctcggccg acggtgtgcg gcacagtgtc
    12601 gtaccggcgg acctggtcaa ccacggcacc gtcgagcgca gcgtgctctt cccggcggcg
    12661 cggatcgggc ccggcgcgac ggtgcgcgac agtgtgctgc tgcccggagc ggtggtgccg
    12721 gccggcgcgg agatcgacgg cgccgtggtg ctcgaggacg gcaccgtcca gcaggtcacc
    12781 accggagccc ggcgatgacc ggcgccgtcc gggccgtgcg atcccgtgag gtgtaccgca
    12841 acccgtggat gagcgtgcgc gaggacgaca tcgtgcacgc cgacggctcg ccgggcagct
    12901 acggggtcgt caccaaaccc gattacgcgc tgatcatccc gcgggacaac ggcctgctgc
    12961 acctggtgga gcagtaccgc tacccggtcg gcgggcggtt ctgggagttc ccgcagggct
    13021 cgtggccggc cgacgccgcc ggcggtgccg ctgacctgct cgcccgtacc gagttggccg
    13081 aggagaccgg gctgcgggcc ggccggctga caccgctggg gcgcatccac gtcgcgtacg
    13141 gctacgccag ccagggctgt cacgtcttcc tggccgaaca gctcacagcg gggcgctctc
    13201 agcgggagcg caccgagtcc gacatgcgcc agcgtgccgt ggacgccgcc ggctgggccg
    13261 acctggtcgg ctccggccgg atcaccgacg ccgcgacgct cgcggcctac accctgctgc
    13321 ggatgtacga cagcggaacg cgacagccca tgccggaagg agccgaatcg tgcacgtggt
    13381 gagcttcgcc ttcgaagccc tcgccttcga cgtagggatg atgcgcggcg ggctcgcccc
    13441 gctggcctgg gaactggccc gccactacgc cgcccaggga caccgctcct cgatcgtcac
    13501 cccggcgcac ggccgcctgc cgtacctcgc cgagcggtac gacctggtcg aactcgacta
    13561 ccgggacgag catgtcgttc ccgtggtccc ggaccccgac gtctgggcgg ggcagccccg
    13621 cgaactgggc ctgcccctgg tcacccgggc ccacctgctg cggcacgagg gcgtcgacat
    13681 ctacctgctc agcgacgagt acctcgatct gctgccggag cggctctacc cggccggcac
    13741 gagtgagggc agcgacctgg cgtacttcaa accgctggtg ttccaggtcg gtgggctgcg
    13801 cttcctgcag tcccggctgg ccggtgacga gcccgccgtc gtgcaggcct acgagccgta
    13861 ctaccactac ctcctgcccc cggtgctggc cggcgacccg cggttccggg tgatgtccac
    13921 ggtggccagc agcatgccga tcgacctggg tgtgtaccgg ccccaggtgg accgcctgct
    13981 cgagcacttc ggcgccggca ccgacctgga ccgctatgtg gagagcccgg tcgcggccgg
    14041 cgccgaccat cccgcggcca cccgcgaggc ggcgctgggc gcggcgatgg ccggatacct
    14101 gccgacgacc cggctctcca gcgggcggcg gcgggccgac tacgtgggcc tgttcgcgct
    14161 gatcaccgac cactgcgaca cggtggactt cctgaccccg gggcagcggc ggttctactc
    14221 gacgttccgg gacaccccgt acgaggcggc gttccggcgg accgcggtgg cccgggtggt
    14281 ccgggagaac gcggcgaaac agttcgtcgg cggctgtgcg ctgccggaga actggctgcg
    14341 gcgggacccg gccgaggtgg accgggcggc gtacctctcc gggctcgggc tggacccggc
    14401 gctgccgacc ttctaccacg tgggccggta ctcgccgcac cacaagggtc aggtggagct
    14461 cttccgggcg gtcgagcgga tcctcgccac cgacacccgg gtcaacttcg tgctgcgctg
    14521 cgccacctcg gccggcggcg gcggcgccag gatcggtgac cccgccttcc aggcggtggc
    14581 cgaccggcac cccggccagg tgcggctctt ctggaccatg gccgacgagg acgaactgtt
    14641 caccgaggcg gtggcggcgg acttcgggtt gttcccgtcc aagtacgaac tggacacctt
    14701 cctgaccgcc caggggcagc tgtgcgcctg cggcgcggtg ccgatcggga ccgcgcagga
    14761 gtcgacccgg cactaccggc accagctggc caccgaccat ccgctggcca ccggattcgc
    14821 cctgccgcgc tccttcaccc cggacgacga acgtctgacc ggcgctctgg tgcgtaccat
    14881 gcgggaggcg ctgcggatgt accgcgacga accgggcgag taccggcggc tggccggcaa
    14941 cgccgccgaa ctcgcccgca ccttccgcta cgccgaggtg tcccggcgac ggctcgccca
    15001 cttcgcgaag ctgctcgacg gcacgccgac agcggccgac ccggagcacg tcatcgggtg
    15061 cggctggttc gaccagttgg acgccgcgca gtgggcggcc cacctgccgc agatccggcg
    15121 cgaagcgatc cgcctcggtg acctggagac gctgcgccgc tgcggcccgg tcgacccggg
    15181 cgcgctcggc gcactgtacg aggccgcgta ccggcgtgcc gacttcgacc ggtgcgtgcg
    15241 ggtcgcggaa ctgctgggcg accggggcag cgaggcggtg tcgctgcgcc ggcgctgccg
    15301 ggtacggccg cacgagcagg gctgggagat ccagtaccgg gcgccgggcg ccgagcaggt
    15361 ggccctggtg gtcggcggta ccgcccaccg gatgcacggt tcggccggcc ggttcagcac
    15421 ggtgctgccc acggtgccga tgccgtcacc ggtgttcctg ctgacgctgg cctccggacg
    15481 gtacgcgtgg gacgccccac cggccaccgc acacctcgcc gacctcgccg gtcagccgca
    15541 cccggcgcag ccggtcgggg ccgggggccg ctgacatgga cggcatcggc accacacccc
    15601 cgcgcgacca ccgggtcgtc gcgaccgacc tcgacggcac cctgctgcgc tccgacctga
    15661 ccgtgtccgc ccggacccgc gcggcgctgc gcgacgcccg ggcggccggc atgatccacc
    15721 tcgcggtgac cggccgcccg gtgatcgaca cccgccggct gctcgccggg ctgggctaca
    15781 ccggcccggc ggtctgcggt cagggcgccc aggtgtacga cttcggcacc gaccggctgc
    15841 tgctgagccg cagcctcgac accgacctgg tgcgcgagct ggtgcgccgg atcgcgcagc
    15901 ggaccggtcc gctcgcgctg gccgcggtga gcgccggcct gggcaccgag ttcctggtca
    15961 ccgccggttt cggtgccccc taccagcagc atcgctggca gctcgtcgac gagccggacc
    16021 tgtggcgtgc gccggtcgcc aaggtgctga tccggcaccc ggaccacgac gacgacacgc
    16081 tcgcggcact cgccgacgag gtctgcggcg cggcgctgtc ggtgatgcac gccggtccgg
    16141 gcctggtcga actgctgccc ggtgacacca gcaaacgcac cggcctggcc tttctcgccg
    16201 ccgaactggg cttcaccggg gccgacacca tcgccttcgg ggacatgccc aacgacctgc
    16261 cgatgttcga ctgggccggg tacggcgtcg cgatggctaa cggccacccc cggctgcgcg
    16321 accgcgccga cgagatcact gtcagcaacg acgcggacgg cgtggccgtg gtgctcgaac
    16381 gtctgcccgc cgtccgggcc ggaaaccgaa aggcaagcct gcgatgacca ccacgacgga
    16441 tgccgcgctg atcgagctgg ccggacggta cggggtgtcg gtcgactgga ccaccgaccg
    16501 cggcgagccg cggacggtgc cggccgacac gatccagcgg atcctggctg tgctcggtgt
    16561 ggacgcgagc tccggccccg cgatcgccgc cgcgctgcgt gccgcggacg acgacgcccg
    16621 gcaccggctg ctgccgtcct gcgtggtggt gcggcagggg gaaccggcca ggggagtcca
    16681 cccggtggcc ggggccgcct atgtggtggc gaccgaggac ggtggccggc acgagacggc
    16741 cgacccgcgc aacgacctcg gccgccttcc gatcggatac cacacgctgc gcgtacgggt
    16801 gggcgaccgg tccgccgccg cgccggtgat cgtggctccg gccgtcctcg gcaccccgga
    16861 ccggcggcac tgggggatgc tggcgcagat ctactccgta ctgtccgaac ggtcctgggg
    16921 gatgggcgac ctcggcgacc tggccgacct gacccgctgg tcggcccggc tcggggcgtc
    16981 gttcgtgctg gtcaatccga tgcacgccta cgtgccggac cgcctggccg accccacgcc
    17041 ctaccggccg ggcagccggc ggttcgccga cccgatgtat ctgcggctgg ccgacgtcgc
    17101 cgagtacgcg accgcggaac cggcggtgcg ggccgaactc gaccgggccg cccgtcaggg
    17161 acacgaactg accgccgagg tgctgcaccg gaacgcgctg atcgaccggg ctcgggtgtg
    17221 gccggtcaag cggaacgccc tggagcggct ctaccgggca ccccgcacgg ccgggcggtc
    17281 cgcggctctg gccgccttca ccgcccgcga gggccggggt ctcgaggact acgccacctg
    17341 gtgtgcgctg gccgaggtgt acggcacccg ctggcgttcc tggccggccg ctctgcaatc
    17401 cccgcacggc ccggcggtcg ccgccgcccg ccgcgagctg gtcgaccgga tcgatttcca
    17461 ccgctggctg gcctggctcg tcgacgagca gatggccgcg gcccaggcgg ccgccgtcgg
    17521 gtccggcatg gcgatcggcg tgatccacga cttggccgtc ggcgtcgacc cggagggtgc
    17581 cgacgcgtgg gcggtgcagg atcatctggc cggcggtgtc acggtgggct gcccggccga
    17641 cgacttcaac ccgctcgggc aggactgggg gttgccgccg tggcgcccgg acaccctggc
    17701 cgaagccggt taccggccgt tcgccgacgt gatccgcggc accctgcggc acagcggggc
    17761 gctgcggctg gaccacattc tcggcctgtt ccggctctgg tggatcccgg ccgggagcgg
    17821 cgcccgcgac ggtgcctacg tccgctacga ccacgaggcc atgctcgggg tgctggccgt
    17881 cgaggcgttc cgggccgggg cgatgatcat cggcgaggat ctgggcaccg tccatccggc
    17941 ggtccgtgcc gaactcgccg accggggcat cctcggcacg tccgtgctgc gcttcgagta
    18001 ccagggcgga tcggagaacc gcagcgggcc gctgccggcc gaccagtggc gtgccggctg
    18061 cctggccacc ctcaccaccc acgacctgcc gagtacggcc gcctggctca gcggtgagca
    18121 cgtggacctg caggaccggc tgggcctgct gaaccggccc cgagccgagg tggccgccga
    18181 cgcggcggcc gaacgtgacg gctggctggc cgagttgcgg cgcaccggtc tgctggagca
    18241 cgagaccgcc gtaccgggga tgagcgccga gtcgctggcc ctgcaccggt tcctggcccg
    18301 gaccccggcc cgcctggtcg gagtgtggct gcccgacctg gtcggcgacc ggaggccgca
    18361 gaacctgccg ggcaccagca ccgagttccc gaactggcag ctgccggtcg ccgacgccga
    18421 cggccggccg gtggcgatgg acgacctggc gtcctcggcc ggcgcccaag cggtcgccgg
    18481 cctgtacgcc gcatcggccg agccggccac cacaccctga cctcgctgac ccgcaccttt
    18541 caaggagatc catgtcggag cacaccgacg tcctcgtcct cggcggcgcc ggcgtcgaca
    18601 ccatcgccta cgtgcccgaa ctgccgctgc cgttccagga cagctacgtg gtcgcggcca
    18661 tcgaaccacg agccgggcag accggcgaca acgtcgctct cggcctgcac acgctgggcc
    18721 tgcgcacgat gcacgtcgac gtgctcggcg acgacccgga aggtgacctg gtccgggcct
    18781 tccacacccg gcacggtctg ccgttcgccg ccctgcccac ggccgccggc accaagcggg
    18841 cggtgaacct ggtcggcccg gacggccgcc ggctgtcgct gtgggacggc agccgggaag
    18901 ccgaggagga ccgctacccg gccgccctga tcgccgcgca caccgcccac gcccggcacg
    18961 tgcacgtctg catcaccccg cccgggcagc acgtgttcgg ccagctcaac gacctgccgg
    19021 tcaccgtctc caccgacctg cacaattggg acggcgccta cgagggcttc gaggtctacg
    19081 ccttcaacgc cgacctggtg ttcctgtcgg cgaccgcgct gaccgacgtg gccgcgacga
    19141 tgcgccgcgt catcgaccgg ggccgggccc ggctggtggt ggccaccgac ggcgcccacg
    19201 gcggatcggt gctggtgcgc ggcgagacgg aggtccggcg gtacgcggcg gtggcccccg
    19261 aggcgccggt ggtggactcc aacggcgccg gtgacgcgtt cgtgtccggc ttcctcttcg
    19321 ggcacctggc cggcgaaccg ctggagacct gcctgcgcta cggcgcgatc gccggcgcct
    19381 acgcgtgcac catccccgcc acccgggccg gcgccatcga ccgggccgcg ctgctgcggc
    19441 cggcggcgtg aagcggccac cgcaccaccc ggtcacggtg gccgacgtgg gcggcaccca
    19501 cctgcgctgg gcacggtggt caccggacgg cggactgggc gaagtgcaca ccacgccgtc
    19561 tccggggcac gcccggcggc ccggcgccgg tgccgccgac ctgcaggcgg aactgatccg
    19621 cgagctggcg tcgcgggtcg agccgggtgc gcgggccggt gtctcgctcg gcgcggccat
    19681 ggaccaccac agtggtacgg cgtacgcctc cgcgccgttg tggggtccgc aggtcagccc
    19741 gttcgacgtg ccggccgccc tgcgcgccgc ccggccggac gtgcactgga ccgtggtcaa
    19801 cgacgtcacg gcggggctgc tgcacctggc cgagatggtt cgcgacgccg gcgtccgcaa
    19861 ggcgtgcctg gtcacgatca gcaccggcat cgcctgccgg acgatggacc tgcgcaccgg
    19921 cggtatcccg gtcgacgcgg ccggcctcca gggcgagatc ggtcacctgc cggcgaccgt
    19981 gctggccgac ggggtgccgg tggtgacccg ctgcgactgc ggtgagccgg ggcacgtggc
    20041 ggcgtcctcg tccgggccgg gcattcgacg ggtcgcggcc gtcctggccc ggcgtgaccc
    20101 ggccacctgg gcgggctccg ggccgaccac ccggatgatg gcgggctcgg gcttcgagga
    20161 cgcgttccgg gccgctctgg acgacggcga tccggtcgcg gcggacctgc tgacggcggt
    20221 gaccgccccg atcgcggacc tgctgcggac cgccctctgc ctggacccgg aactcgacct
    20281 gatcgcgctg accggtggag tcgcccacgg gctggaaccg cactactcgg cggcggtgca
    20341 cgaccacctg cggcgccggg ggctctacct gacctccgag cgggagccgg actggttgac
    20401 cgggcggatc cgggtcgtcc cgccggcgac ggccgatccg ttggtcggcg ccggtctggc
    20461 cgcactggcg gcggggccgg tcccggcgta ctccggtggt ggccgggaag cgttggtcgg
    20521 gcgatgagcc ggcaccgcgc gatcgtgcgc accggcaccg gcgtggtggt cgccgacgtc
    20581 ccgaccccgg tgccggggcc gggagagctg ttggtcggca ccgagtgggc gggactgtgc
    20641 ggcaccgaca tccagatgct gcgcggcctg cgcgacgatc ccgaaccgat catcggccac
    20701 gaggggatcg cccgggtgat cgcggccggc gacggcgtgc ccggcacgct gcggccgggg
    20761 accctggtgg cggtcaaccc gacccaccgg gacgatccgt cgttcctgct cgggcacaac
    20821 gttcccggcc tgctgcagga acggacgctg ctgccggcca ccgcggtctc cggtggcttg
    20881 gtgctcccgc tgccggacgg caccgacgtc acgctgggcc cgctgctgga accgctggcc
    20941 gtggtcagct atgcgctgag ccagctcggc gccgtccgcc cggccaccct ggtgatcgtc
    21001 ggcgacggaa cggtgggtca cctggccgcc cgggctgcgg tgacctggct ggcggagcgg
    21061 ccccgggtgg tgctggtgca ccacacggca gcggggcggg acttcagcgc ggccgggccg
    21121 catccggcgg acgttctgct caccaccggc gagctggcgg gcagaccgct gccgggaccg
    21181 gtggccgccc tgctggcgac cccacgggac gcgactgtcg aggccctgga ggcggtcctg
    21241 gccgcggccg gcgccgatgt gctgatcgac gtgctgggcg gcctgccccc gggcgcgcga
    21301 tcggcgatgc tgcccggtgt cgatctcacc gccgtgcggg cggccaactg cggcggcttc
    21361 ccggaaccgg ctctggtcac caccacctcc ggcggaaccc ggctcttcgg gcatcgcggg
    21421 gtgggcaacg cgcacctgcg ggcggcggcc ggcgagctgg cccgcgaccc ggaccggtac
    21481 cgggatctcg tcacccatcg cagcgatctg gccggcgcgg cccggatcat gaccgcgctc
    21541 cggagcggcc gggaccggat catcgacggc cgccgactgg tgaagctcgc gatccaggtc
    21601 aatgtcagag aggatcatcg atgagcggga ctctggtggg ccgccgcgcc ctggtggtgg
    21661 gcggaaccac gggcatcggc cggggcatcg ccgacgcgtg ggccgcggcc ggcgccgagg
    21721 tgaccgtctg tggccgcagc gagccggccg gcgatggcgc cgccgggttg cactgggagc
    21781 cgctcgacct gacccggacc ggggaggccg gtgcgcgcct ggaacggatc gccggtgacc
    21841 gggtcgatct ggcctgcttc gccgcggtct cctacggggc ccggcgcgcc gtcttcgagg
    21901 acgtggcggt ggacgaatgg cgtacccagc tggacatcaa cgtgcacggc ctgtggctca
    21961 ccctgcgggc ggcactgccg gggctgcgtg ccgcccggcc cggcctgttc gtgggcgtct
    22021 cgtccgaggt ggtctacaac gccgggcccg gccgctccgg gtacaccgcc tccaaggcgg
    22081 ccgcgaaggc gctgctggag tcggtggccc aggaggagga cgagagccgg gtccggatcg
    22141 tgcaggtgct gccggccggg atggtcgata ctccgagcat ccggcgccgt cgcccggccg
    22201 gcttcgacta cagcgactac atggtgcccg ccgatttcgc gcgcaacgcg ctggaactcg
    22261 ccgccacggc cggcgccggc caccacgggg acagcctggt ggtcgacagg ggcggcgact
    22321 ggtggtcggt gcgcgagcgg atgccggtgt cgcagagccg gccggtgcgg acgtgacctg
    22381 ccgggtgggg ctgaccgagt ggcggctggc gccctcgggt gcggcggcca tccggctggc
    22441 cgcggcggtc ggtgccgacg ggatccagct cgacttcggc ggcccgggcc gtggcgtgct
    22501 ggtggacggc ccgggccgtg ccgggcagct gcgggcggtc gccgacgagg cgggagtgga
    22561 cctgctcgcg ctggccggca acctgctcaa cgacatcggg ctcacgtcgc agccggcggt
    22621 ggtccagccg gtgctggccc ggctggccga cacggcgacc gagctcgggg tgccgctgct
    22681 catcgtgccc agcttccggc gcagcgcgat caccgacgcg atgtccttca cccgcacagc
    22741 agccgccctg cgctgggccg tgtcgctggc cgaggcccgg ggaatcgtgc tggccagcga
    22801 gaacgtcctg cccccggcgc gggcccggca gctggtcgag gaggtcggct caccggcttt
    22861 ccggctgctg ctggacacct tcaacccggt ccggtacgga ctcgacccgg cctggctggc
    22921 caccgagctc cggccgtggt gggccgacca gatccacctc aaggacggcc cgccggacac
    22981 cgggccgtcg ccgctgctcg gtgcgggaca gggcggggtg cggcgcaccc tgaccgcgct
    23041 cagggggagc cccgcaccgg tacgggccct ggtgctggag aacgactacc gcgacggcca
    23101 cggtgcgcgg ctgcgagcgg acctggagtg ggcccgccgg gccgcggtga acgcgagaga
    23161 atccgagaaa gggaagctga cgtgagtggt gtcgagacgg taggggtgca cgcggatgcg
    23221 caccgcgact cgtggcaggt gcgggcccag aagcagatca cctacgaggt gcgcttccgg
    23281 gacgacgtgt tcgggctgga ctccaccgac ctgctggagg ccggggcgga cggggccggt
    23341 tcacggcggc ggttcgtggt ggtggacagc gccgtcgacg ccttgtacgg gtcccggatc
    23401 cgggagtact tcacccatca cggcatcgat cattcgatcc tggtgatgcg ggtgggcgag
    23461 acggtcaagg acttcgacac ggcgggccgc atcgtcgccg cgatggacgc cttcggactg
    23521 gcccgccgcc gggagccgat gatcgtcgtc ggtggtgggg tgctgatgga cgtggccggt
    23581 ctggtggcca gcctctaccg gcgcggcacg ccgttcctgc gggtgccgac gacactggtc
    23641 ggactgatcg acgcgggtgt cggcgcgaag accggggtca acttcaacgg ccacaagaac
    23701 cggctgggta cgtacgcccc ggctgatctg accctgctgg accgccgctt cctggccacc
    23761 ctggaccggc gccacctcag caacgggctc gccgagatgc tcaagatcgc gctgatcaag
    23821 gatgccgagc tgttccagct gctggagcgg cacgggcggg tcctgatcga ggaacggttc
    23881 cagggccgta ccggaaccgg tgaccgggcc gccgtccggg ccctgcgcgc ggccacccat
    23941 ggcatgctgg aggaactcgg ccccaatctg tgggagagcc ggctggaacg cagtgtcgac
    24001 tacgggcaca cgttcagccc gaccatcgag atgcgcgcgc tgccggctct gctgcacggc
    24061 gaggccgtgt gtgtggacat ggcgctgacc acggtgctgg cgtaccggcg gggtctgctc
    24121 gacgtcgcgc agcgggaccg gatcttcgcg gtgatgaccg ccctgggcct gccgacctgg
    24181 catccgctgc tcacgccgga ggtgctggag gcggcgttgc aggacaccgt ccggcaccgg
    24241 gacgggtggc agcggctgcc actgccggtg gggatcgggg gtgtcacgtt cgtcaacgac
    24301 gtgacggccg ccgagctgca ggccgccgcg ctgatgcagc accggctcgc cgaggacgcc
    24361 ctgctgctgc gcgcctagct cgggccgcgg acgccgatcg ccggaagcga ccggcgtccg
    24421 tccgcccacc ggttgccgtc aggtccacca ggaacggttg gcgcgatacc acgcgaccgt
    24481 ttccgcgatg ccgtcggtga aatcgacccg cggccggtaa ccgagttccc cggcgatttt
    24541 cgaatagtcg agagaatagc gccggtcgtg acctttgcga tcggtcacga aagatatgcg
    24601 cgaagccggg gcgccgcacg cctcgaggag gatctcggtc aattcgagat tcgtcgcctc
    24661 ccacccaccg ccgatgtgat agacctcgcc tgcccggccg gcacccaggg ccagggcgag
    24721 accgcggcaa tggtcgctga cgtggagcca gtcgcggatg ttgcggccgt cgccgtagac
    24781 cggtacgtcg agcccgtcga gcagcctggt gacgaacagc ggaatcattt tctccgggaa
    24841 ttgccggggc ccgtagttgt tcgagcagcg ggtcaccacg acgtccatcc cgtgcgtctg
    24901 gtggtaggcc agagcgagga ggtcggaccc ggctttgctc gcggcgtacg gcgagttggg
    24961 cgccagcgga tggccctcgg cccacgagcc ggtgtcgatc gacccgtaca cctcgtcggt
    25021 ggaaacatgc aggaagcggc cgatatggtg gcgtagcgcg gcgtccagta gcacctgagt
    25081 gccgaccagg ttgctggcca cgaaggggcc ggaggcgacc accgagcggt cgacgtgggt
    25141 ctcggcggcg aagtgcgcca cggtgtcgtg ccgcgccatc agcccctcga ttagaccttc
    25201 gtcacagatg tcgccccgaa cgaagctgaa acgagggtcc gccgacgctt cggcgagatt
    25261 tctgagattg cctccgtaac ccagtttgtc gacgaccgta acctgcgtca cgggttgtgg
    25321 tgtggcaatg tcgccactga tcagggaagt tacaaaatgg gacccgataa agccggctcc
    25381 gccggtgacc aagattttca tcgccgggat tgtagcaatg ccgccaatgg gtgcccgatg
    25441 ttcggccgag ccatttacgg ggcttgctga tatggtcggt cacgtgcgcg gaatattgct
    25501 ggccggggga accggctcac ggcttcgacc ggtgacctgg gcggtttcca aacaactgat
    25561 gccggtctat gacaaaccga tgatctacta tccgctggcc acgctcgtca gctgcgggat
    25621 ccgggagatc ctggtcatca cgaccgagac cgaggccgcc cagttccagc ggttgctggg
    25681 tgacggctcg cagtggggcc tgcgtctgga gttcgccgtg cagcagcgcc ccgggggcat
    25741 cgccgaggcc ttcctcatcg gcgaggagtt cctggccggt gggccggtgg cgctcatgct
    25801 cggcgacaac ctgctgcacg gggtggactt ccgcccctgc gtgcagcggg cacgcgagac
    25861 ggccggtggg cacgtcttcg gagtggcggt ggccgacccg tcggcctacg gggtggtcga
    25921 gttcgacgcc gccgggcggg tgctgtccat cgaggagaaa ccggtccgtc cccgctcgcc
    25981 gtacgcggtt cccggcttct acctctacga cgccgatgtg gtcgagacgg cccggtcgct
    26041 gcggcccagc gcccgcgggg agctggagat caccgaggtc aaccaggcct acctgcggcg
    26101 cggcgcactc tcggtgacgc tgctgggtcg gggcgcggtc tggctcgaca ccggcaccct
    26161 ggccgactgc atgcgcgcgg tcgactacgt gcgcgccatc gacgagggcc agggcatcaa
    26221 gatcggctgt gtggaggagg cggcctggcg ggccggtttc ctcgacaccg cgcagctgcg
    26281 tgccctcgcc gagccgttga tgagcagcgg ctacggacag tacctgctgg ctctgaccgg
    26341 cgacgggctc agccgtaccc cgcagtggcc ggccttgacc gccgccgccg ggtgagcggc
    26401 ccgcggaggg tgaccggccc gggcggcgaa gggccggccc cccgcgaggc gaggaaccgg
    26461 cccggtccgt ggtcgccgca gcgccggtca gcggactccg gtcaccgaca tgagccggcc
    26521 ttgcgcatcc cgctcagtca catagaactg tccgtcaccg gagggcaggg cggccgccgc
    26581 ctggaacgcc gggtactgcc acagttccgg tgcctgccgc cgctgcttct cggtgaggcc
    26641 gtcgcgctgc gcggtcagcc ggatgctgcg atagtcgccg gcgaggtcac cgtcgaccag
    26701 gcgcagccca ccgttcgggg cgtgcacgag gtcgtagacg cgcccgtcgg tggctgcccc
    26761 ggccggttcc agcgtgtcgg gcgtaccggt ctgccaggcg atcgtgtccc ggtccacccg
    26821 caccgcgtcg gccctggtca gatcgagttt cgccggtttc accaccgacg gcagcagccg
    26881 ttcctggacg cccgcctgca cccagacctc ccggcccgcg tcggcgaact ccagccgctg
    26941 gtcggtcggc agatccttgg cctcgccggc gtgcatgatg tagctgagac cggtggcccc
    27001 ggccgccagc gggatccgga agaccgcacc gaagctgtcg aacgactccg gcagcagcgg
    27061 cgcgccccag tcggcggtgg gggtggccgc accgtcccac aggtgcaggc cccagccggt
    27121 gtaatcgccg gctggacgcc ggtagtgcag gatcgcggtg ttcggcgcgg gtgcgggcgc
    27181 cggaccctgg taggagatgg ccgggtcgcc ctggtgcagc cagatcccgg gtgtctgctg
    27241 gggattgagc gagcggtcgg cgtcgacgtc cttgacaccg ttggcgtcac tcacggtgaa
    27301 ggtgaccttc gtggcgccgg gccgcagttt gacccaggcg aagcgcccgt aggcgtccgt
    27361 cccggtgaac ggctctccct gcgggtcgag cgcggccgcg tcgacgtcgc cggtggcgtg
    27421 caggcgccag ccgtcgtagt cgccggcggg acgctgatag tgcacgacgg cgtagcccgc
    27481 ctcggcccgc acggtgccga cccggatccg gctggtggtg gtggcggtac ggcctcggcc
    27541 gtcccgggcg accgcccggt actgcacctc ggcgccgccg gccagtccgg tcaggtcgtg
    27601 gaacacccgg tacggggccc gtccggccgt gccgatcggc tgccacggcc cgttaccggc
    27661 gcgggcggag aaggtgacgg tggacagcgg gtcgccggtg acggcggcgg tcagttcggt
    27721 gcggcccggc acgagggtcc cggccgcggg tgcggtgatc gtcacggcgg gggcgccgtc
    27781 cgccgcgggg atcggtttct cggcccgata ggccaccgcc gacagcgccg gcacggtgat
    27841 ggtgagccgg ccgtcggcac cggtggccgc cgtctcgccg gtgccgtaga gaggctggaa
    27901 gccggagccc ggggtgtagg tgtcgaaggt gacggtctgc gcggtggtcg cgttgttcac
    27961 cgcgatcaca tactcggcac gctggtcgcg gtcgatgcgg gaggcggcga agaccccggc
    28021 gcggtcggcg gcgtaccggg tgatctgctc accgtcacgc agtgccgggt gggccttgcg
    28081 cagcgcgccc agctcggcga tggtgcggta gagcgggtgc ccggtgtcgt ggttgtcgct
    28141 cgcgtgggtc ttgtcggtgc cgatcaggcg gtcgtccagg tagtccggtg tccggctggc
    28201 gaacatgtcc tggcgcgagc ccttgtcgcc gagggcgccg gtgaagccct gctcgtcgcc
    28261 ggagtagacc accggctggc cgcgggtgag gaacatcagc tcgttcgcca gttcgagccg
    28321 gcgcagcccg ttcggatcgg agccggcctt gatcagagtg gcgatccggc ccatgtcgtg
    28381 gttgccgagg aaggtgggca gccggccggc gtcggtcccg gcggcggtgt agaggtcgtc
    28441 cttcgcgtac aggccggcca ggctgctggc cggtgccttg ccggtgacgt agctctgggc
    28501 cgcgccctgg aacgggaagt cgagggtcgc gggcaggccg ccccggcgga cgaacgtcga
    28561 ggtgacttcc tggtccttgc tccaggcctc accgaagagg aagaagtcac gcttgcccgc
    28621 cttgtccgcg gccttgccca cgccctcggc gaaaggccgc cagaacgcca ggtcggtggc
    28681 tttgagggtg tccagccggt agccgtcgac gccgaaccgc cggatccagc cggcgtagat
    28741 gtcggtcagc ccgtgcagca cctcgggccg ctcggtccac agatcgtcga ggccgccggt
    28801 gaagtcgccg tattcggcgt tctccccgcc gaaggtggtc tcgccccggt tgtggtacat
    28861 ggtcgggtcg ttgagccagg cgggtgcctt ggcggtggcg tcggacggct tctcgaagaa
    28921 cggccggtgg gggaacgact tctcgtcgac cttggggaag ccgtgtgtcc cgtcggcgta
    28981 gttgcggtcc tcgaagggac gacccgcggt gtcgcggtag ggcgcggttc ccttgtcggc
    29041 gtaggcggtg ccctcggcgt tcttgatcac gtcggcggtg tggttcacca cgatgtcgag
    29101 gtagatcttc atgccgcgcc ggtgggcgag gccgaccagc cgcttgaggt cctcgttggt
    29161 cccgaagtgc gggtcgacct gggtgaagtc ggtgatccag tagccgtggt agccggcgga
    29221 cgcgttcgga cccgtaccct gcaccggctt gttcttgaag atcggcgtca gccagatcgc
    29281 cgtggtaccg agcccctgga tgtagtccag tttgtcgatc acgccctgga tgtcgccgcc
    29341 gtggtagaag ccggcgtcgg tggggtcgta cccggtggtg agccggtctc cggtcagccc
    29401 gccctgatcg ttgccggtgt cgccgttggc gaaccggtcg ggcatcacca ggtagagctg
    29461 ctcggcgtgg gacggccggt ccggcggcga ttcggcctgc gcggcccgcg gagccggcag
    29521 gccaccggcg gcccccacca gcacgggcag cagcgcccgg acgatatgag atttcagtct
    29581 ttcatccatc gtggaccctc tctcgcgatc gctgggacgc tagcccggcg ggagacgtgc
    29641 ccgcaagaac ttgctgtttt agcaagaagt ttcagaaccg ggacggcacg ctgtagccca
    29701 gatcatagat cgcgatcagg tagttaaaac tgcagctcaa cggcaattgc gcatggtctg
    29761 aggtcgatgt acttaaagct ctgcgcaagc ttagggttga agtggcggtg atgcatccat
    29821 cactgtatgc gcatctgaat gacgtcttct gcaagttctt gcagcggtct ccgggccctg
    29881 cccttcctcg tcatcccttc acaaggagaa gctcgtgcaa cgtcacgcca ggcatgccat
    29941 cgccgcggcg gtagccgttt cgctgctgcc gccgtcactg ccggctcatg ccgccggggc
    30001 ttcggccgtg gtgccgtacg ccggtaaccc ggccagtctc aagcaggacc tctgctacca
    30061 gatcgccacc gaccggttca gcgacgggaa cccggcgaac aacaatccgg gcaacgtgcc
    30121 cggcatgttc gccgacaaga ccaagctgaa cgaccggcag gagtggctca aatacatggg
    30181 aggtgacttc gccggcatca cccagcggat ggagtacctc aagaacctgg gcgtcggcgc
    30241 gatctggatc tcgccgcacg tcgacaacat caacgttccg gcgaacggcg ccaccggtta
    30301 ccacggctac tggccgcgcg acttcaagcg gctcgaagag cacttcggca ccgacgagga
    30361 gttcgacgcg ctggtgtcgg cggcgcacgc cagcaacatc aaagtgatca tggactggac
    30421 gccgaacggc accaacccgc cgaaccaggc cgaggacggc gccctctacg acgatgggca
    30481 gctggtcggc aggtacgggg cggacagtgc cgggcacttc caccacggcc cggcgatcgg
    30541 cgacttcaac gatcgctacc aggaccagta ctacagcctg gccgacatcg ccgacctcga
    30601 ccagcagaac ccgcgggtcg accagctgct caaggacgac gccaactact ggatggaccg
    30661 cggggtcgac ggcatccggg tcgacgccgt caagcacatg ccgctgagct ggcagcggtc
    30721 cttcgccgac gcggtcacct cgcacaagag cgcggccatc ttcggcgagt ggtacatggg
    30781 cgaccagtcc gatccgctct acgccgacca ggtcaagttc gccaacacca gcggcatcgc
    30841 ggccatggac ttctacacca accgctcgat ccgcgacacc ttcgccggcg ccggctcgat
    30901 gaagtccctg gacgcggcga tcaccaagac caaccgggac tacctctacg agcaggatct
    30961 gatcacgttc ctggacaacc aggacacccg gcgcttcggg acgctcaaca gcgatccggc
    31021 ggccctgcac cgggcgctcg ccttcctgct caccacccgg ggtacgccgt gcctgttcta
    31081 cggcaccgag cagtacctgc acaacgacac cggtgagggc agcaacaagg gcaaggaccc
    31141 gtacaaccgg cccccgatgg ccagtttcga caccgacacg gtcgcctacc gggagatccg
    31201 cgccctctcc gacctgcgcc ggtcgaaccc cgcggtggcc tacggggacc accagcagcg
    31261 gtggatcaac gacgacgtgt acgtctacga gcgccggttc ggcgacaacg tgctgctgac
    31321 cgccatcaac aagggctcgc acgagtaccg gctcgacggg ctgcgcaccg cgctgccggc
    31381 cggcacctat cgcgacgtgc tcggcggcac cttcggcggc tccgacctga ccgtcgagga
    31441 cggcgacggc accgaccggt cgaccgtcgc gccggtgctg ggtgccgggc aggtcgccgt
    31501 ctggtcgtac cgggcgccgg tggacaccga gccccggatc ggcggggtcg ggccggtcgt
    31561 gacccgggcc ggcgccaccg tcaccgtcga gggcaccggc ttcggctccg gcggaaccgt
    31621 cgcgatcggc ggagtccccg cgaccgtcca gcagtggacg gcggaccgta tcaccgccac
    31681 cgtcccggtc ggcgttccca ccggggccgt ccaggtgacc gtcggcaacg gctccggcac
    31741 cagcaacggg tacccgatca ccacccgtac cggaaaaccg gtcccggtgc agttcaccgt
    31801 tcagaacccg ccggccaccg cgcccgggga gtcgctctac ctgaccggtg acgtcgccga
    31861 gttggggcac tggtcgacca gcccggacca gaccgcggga cagctgctgc gggtgccgaa
    31921 cgagtcccgg ggcgtcctcg tcgccgacct gccggccggg gcgccggtcg agttcaagtt
    31981 cgtcaaggtc gcggccgacg gcacggtgac ctgggagggt ggtgccaacc accggtacac
    32041 cgtcccggcc ggcggcaccg gcacgaccac gctcacctgg cagcgctga
//
