LOCUS       NC_013132              11166 bp    DNA     linear   CON 26-AUG-2019
DEFINITION  Chitinophaga pinensis DSM 2588, complete genome.
ACCESSION   NC_013132
VERSION     NC_013132.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN00001914
            Assembly: GCF_000024005.1
KEYWORDS    RefSeq.
SOURCE      Chitinophaga pinensis DSM 2588
  ORGANISM  Chitinophaga pinensis DSM 2588
            Bacteria; Bacteroidetes; Chitinophagia; Chitinophagales;
            Chitinophagaceae; Chitinophaga.
REFERENCE   1  (bases 1 to 11166)
  AUTHORS   Glavina Del Rio,T., Abt,B., Spring,S., Lapidus,A., Nolan,M.,
            Tice,H., Copeland,A., Cheng,J.F., Chen,F., Bruce,D., Goodwin,L.,
            Pitluck,S., Ivanova,N., Mavromatis,K., Mikhailova,N., Pati,A.,
            Chen,A., Palaniappan,K., Land,M., Hauser,L., Chang,Y.J.,
            Jeffries,C.D., Chain,P., Saunders,E., Detter,J.C., Brettin,T.,
            Rohde,M., Goker,M., Bristow,J., Eisen,J.A., Markowitz,V.,
            Hugenholtz,P., Kyrpides,N.C., Klenk,H.P. and Lucas,S.
  TITLE     Complete genome sequence of Chitinophaga pinensis type strain (UQM
            2034)
  JOURNAL   Stand Genomic Sci 2 (1), 87-95 (2010)
   PUBMED   21304681
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11166)
  AUTHORS   Lucas,S., Copeland,A., Lapidus,A., Glavina del Rio,T., Dalin,E.,
            Tice,H., Bruce,D., Goodwin,L., Pitluck,S., Kyrpides,N.,
            Mavromatis,K., Ivanova,N., Mikhailova,N., Sims,D., Meinche,L.,
            Brettin,T., Detter,J.C., Han,C., Larimer,F., Land,M., Hauser,L.,
            Markowitz,V., Cheng,J.-F., Hugenholtz,P., Woyke,T., Wu,D.,
            Spring,S., Klenk,H.-P. and Eisen,J.A.
  CONSRTM   US DOE Joint Genome Institute (JGI-PGF)
  TITLE     The complete genome of Chitinophaga pinensis DSM 2588
  JOURNAL   Unpublished
REFERENCE   3  (bases 1 to 11166)
  AUTHORS   Lucas,S., Copeland,A., Lapidus,A., Glavina del Rio,T., Dalin,E.,
            Tice,H., Bruce,D., Goodwin,L., Pitluck,S., Kyrpides,N.,
            Mavromatis,K., Ivanova,N., Mikhailova,N., Sims,D., Meinche,L.,
            Brettin,T., Detter,J.C., Han,C., Larimer,F., Land,M., Hauser,L.,
            Markowitz,V., Cheng,J.-F., Hugenholtz,P., Woyke,T., Wu,D.,
            Spring,S., Klenk,H.-P. and Eisen,J.A.
  CONSRTM   US DOE Joint Genome Institute (JGI-PGF)
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2009) US DOE Joint Genome Institute, 2800 Mitchell
            Drive, Walnut Creek, CA 94598-1698, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 08/26/2019 00:28:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
            Annotation Method                 :: Best-placed reference protein
            Annotation Software revision      :: 4.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
            Genes (total)                     :: 7,171
            CDSs (total)                      :: 7,077
            Genes (coding)                    :: 7,009
            CDSs (with protein)               :: 7,009
            Genes (RNA)                       :: 94
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 19 of 68
            Pseudo Genes (incomplete)         :: 47 of 68
            Pseudo Genes (internal stop)      :: 11 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
            ##Metadata-START##
            Organism Display Name :: Chitinophaga pinensis UQM 2034, DSM 2588
            Culture Collection ID :: DSM 2588, ATCC 43595, LMG 13176, UQM 2034
            GOLD Stamp ID                     :: Gi02244
            Funding Program                   :: DOE-GEBA 2007
            Gene Calling Method               :: Prodigal
            Isolation Site                    :: Pine litter in Australia
            Isolation Country                 :: Australia
            Oxygen Requirement                :: Aerobe
            Cell Shape                        :: Rod-shaped
            Motility                          :: Motile
            Sporulation                       :: Nonsporulating
            Temperature Range                 :: Mesophile
            Temperature Optimum               :: 23 - 24C
            pH                                :: 7
            Gram Staining                     :: gram-
            Biotic Relationship               :: Free living
            Diseases                          :: None
            Phenotypes :: Biomass degrader, Chitin degradation
            Energy Source                     :: Chemoorganotroph
            ##Metadata-END##
            REFSEQ INFORMATION: The reference sequence was derived from
            CP001699.
            URL -- http://www.jgi.doe.gov
            JGI Project ID: 4082984
            Source DNA and organism available from Hans-Peter Klenk at the
            German Collection of Microorganisms and Cell Cultures (DSMZ)
            (hans-peter.klenk@dsmz.de)
            Contacts: Jonathan A. Eisen (jaeisen@ucdavis.edu)
            David Bruce (microbe@cuba.jgi-psf.org)
            Whole genome sequencing and draft assembly at JGI-PGF
            Finishing done by JGI-LANL
            Annotation by JGI-ORNL and JGI-PGF
            The JGI and collaborators endorse the principles for the
            distribution and use of large scale sequencing data adopted by the
            larger genome sequencing community and urge users of this data to
            follow them. It is our intention to publish the work of this
            project in a timely fashion and we welcome collaborative
            interaction on the project and analysis.
            (http://www.genome.gov/page.cfm?pageID=10506376).
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Annotation Pipeline (PGAP)
            set; GeneMarkS-2+
            repeat_region
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..11166
                     /organism="Chitinophaga pinensis DSM 2588"
                     /mol_type="genomic DNA"
                     /strain="DSM 2588"
                     /type_material="type strain of Chitinophaga pinensis"
                     /db_xref="taxon:485918"
                     /note="type strain of Chitinophaga pinensis"
     gene            1..2856
                     /locus_tag="CPIN_RS27450"
                     /old_locus_tag="Cpin_5548"
     CDS             1..2856
                     /locus_tag="CPIN_RS27450"
                     /old_locus_tag="Cpin_5548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015267782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH31"
                     /protein_id="WP_012793142.1"
                     /translation="MKKKRLFSVLAFTCCIHFAYAGKIERLKDGLLVRLEKTTAGGVKQ
                     VKLQVITDNIIRVTASPADSISTTPSLMAIVTGTREVKWTSEEKNNQIILKTSTLTASI
                     DLSTGEVVFKDASGHVILQEKKGGGKTFTPAIIDGKPLYKLQQVFESPAGEAFYGLGQH
                     QTGLMNYKDQDVDLTQYNSIAVIPYLVSSNHYGILWDNYSITRFGDDRPYEELTSLELT
                     DKNGKPGGLTATYALRNKPDSIFLQKQESAIDFTFLPDLKKMPAGFPMGKGIITWEGNI
                     ASKTGGQEKFYMTASGYVKVWIDGELKLDKWREGWNPGPSVFRHQLEKGKQHKIKVEWI
                     PESDQAFVAVRHLSPTPASLQNKAAFSSEAGEKIDYYFVYGQQMDDVINGYRNITGKAA
                     IVPKWALGYWQSRERYKTQRDVISTVQEFRKRQIPLDNIVMDWSYWQENAWGSQEFDPA
                     RFPDAKGMIDSLHNIYHTHFMISAWPKFYKDIHNYNLFNDKGWLYKQSINDGIRDWIGQ
                     GYVSTFYDAFNPGARKLFWQLLSRHLFSKGVDAWWLDATEPDVLSNATIDYRKQLMNPT
                     ALGPSTQYFNTYALLNAKGIYEGQRQEKPDQRVFILTRSAYAGMQRYAAATWSGDIAAR
                     FDELARQIPAGLNFGMSGMPYWTTDIGGFYVEDKYDQPDPKGADLEEWRELNTRWFQYG
                     AFCPLFRSHGQYPYREPFNIAPDNSVEFNSMVYYDKLRYRLMPYIYSLAGHTYHNGYTI
                     MRGLVMDFGKDTAVQRIGDQFMFGPSLLVNPVYTYKARQRQLYLPANTGWYNLYDGTYT
                     EGGKHITVDAPLDRIPLYAKAGSIIPFGPAMQYTAQRPADTITLYVYAGSNGKFTLYED
                     EGINYNYEKGQYSTIPFTYDDASKTLTIGKREGKFSGMLQQRTFRIVHAGKEKPVSLNL
                     DKLDAIVMKYEGTEKKISLKN"
     gene            2967..6077
                     /locus_tag="CPIN_RS27455"
                     /old_locus_tag="Cpin_5549"
     CDS             2967..6077
                     /locus_tag="CPIN_RS27455"
                     /old_locus_tag="Cpin_5549"
                     /inference="COORDINATES: protein motif:HMM:TIGR04056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gnl|TC-DB|Q45780|1.B.14.6.1"
                     /protein_id="WP_012793143.1"
                     /translation="MKTAYKIRDFVTACMIPVSCGLSSALLLTMLSGNVAMAQTPKRAL
                     SGKVTTGKDNSPLPGASVRIKGTNNGAITDGTGSFNLQVGDADSLEVTLVGFTRQVISA
                     RGKSSLTVNLSEGSTGLDEIVVVGYGTEKKKLVTGAIDHVNTQQLEQNHALRVDQALQG
                     QTPGVQITATSAQPGESMKVRIRGTSTVGNADPLYIVDGVPTYDISYLNASDIASMDVL
                     KDAASSAIYGARAANGVVLITTRKGRAGTMKIAYDAYYGTQNPSHKVSVLNAHDYGVIM
                     NEMAINSGGQPYFTIDQLSKLGKGTDWQEAIYNKNAPMQNHSLSFAGGNDASVFSSSIA
                     YTEQAGIIGVNDQSRYDRLSFRMNSEHKMYKDIIIFGENLTYTQSRKRGIGVGNIYNNA
                     IRSVFSTSPLFPVYDENGNYAKSSFNVEEANPVALMDYQNQNKDKTNRIMGNTYLQISP
                     VKGLSIRTDFGIDISSTDSRSYTPLYNLSTNVINEHSRATQGIYRTNSWNWDNTINYQR
                     DFGKHNIGVLVGMNANETKANYLYGYKQDLTKTGLDNAVIDNGTTDSTQRIYGADSAAT
                     IYSYFGRISYSYADKYMFTAVVRSDASSRFGPNNRRAYFPSFSVGWVPTNEDFFKPTWL
                     EFLKIRAGWGQNGNLPTGYYQYLSTISTQYLGYYFGSGDAPAIGAAPIKISNPDLKWET
                     SEQANIGFDANFLKDFNLTVDIYRKTTKDWLVPVNVPAVSGAATVLINGGDVRNQGVEI
                     SLGYHHTFHDLSVGVNGNMGINRNEITDIPNKEKIINGATAITYPSMPEFYRAQVGFPM
                     GYFYGYKTAGIFQNDQEVAAYVSKDGKKIQPNAQPGDVRFQDLNGDGVIDSKDQTQIGN
                     PYPKFTYGLNINLGYKGFDFSASLYGNYGNQIWDGTHDFSRPLSNYTTEILGRWTGEGS
                     SNRLPRVTDGAELNQNWIRSSDLYVHNASFLRVKSLNLGYDFKQLLHTLPLGQLRLYVS
                     ATNLFTFTPYKGVDPEVGYGPTGWASGIDLGTYPQPKSVLVGLNVKF"
     gene            6096..7658
                     /locus_tag="CPIN_RS27460"
                     /old_locus_tag="Cpin_5550"
     CDS             6096..7658
                     /locus_tag="CPIN_RS27460"
                     /old_locus_tag="Cpin_5550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008465421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RagB/SusD family nutrient uptake outer membrane
                     protein"
                     /protein_id="WP_012793144.1"
                     /translation="MKKIFASIIAISLFAACSKDFLERSPVDEQTETSFYQTPDQALQA
                     LVAVYNQLNIGDYDNIHLVSELASDNCFGGGGTSDLVWKQWDRFQEASNMNLGLWQKYY
                     TGIYRANVLLSKIDGVNWGTDSTLKNTYVAEARFLRAYFYFDLARFFGNVPLATKPLTV
                     SEYNMPQATPADVYKQIAEDLKYAAEKLPAVAYQGIPTSNYGRVTKWAAQALIGRVFLY
                     YTGYYNQNDLAGVVTKAQAASYLENIINAGGYGLVDSFPRLWQASAASFVGEDNKETIW
                     SIKFTHKGLGNWDQHNGNRMQVDIGIRSQVLNPYYKGWGAGTVNSKLWNAYDGADTRRN
                     ASIISIEDENLTAYAIGDQSQYTGYFWKKYMPLNDGNADSKGGNFQIDNYFDDVIIRYA
                     DVLLMAAELNLGTDLGKAQGYYNQVRDRAFLNTTSRKTLTATNGKSLIMEERRLEFALE
                     GLRYWDLLRQGMSVAKAAIDNSSSDAQFNVSFRTETQGLFKIPEQEINLSSGVYRQNPG
                     WAN"
     gene            7688..8452
                     /locus_tag="CPIN_RS37120"
                     /old_locus_tag="Cpin_5551"
     CDS             7688..8452
                     /locus_tag="CPIN_RS37120"
                     /old_locus_tag="Cpin_5551"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_012793145.1"
                     /translation="MKKFITLSLLALSALLVSCTKEDEESLDGPSISKDNLKFSVTQEQ
                     GHDNIVMLNSLTAGSYIPFWEYTGGFSKNKKDTINLPFAGKYTIRYTIYTPGGPLADSS
                     DITVSKNDPEYFASPLWKLLTNEQTGKTWVWATDIPGGICYGNGSGGATAPEWWQNGIA
                     YLTEQGVAADEMTFDLNGAKNYSLTHAGTAKKALFELDTLNRTLKITGADIPLGGKVTY
                     VIVKLTADELTLAQQGDGWRNIWMYKRKGFNY"
     gene            complement(8670..9062)
                     /locus_tag="CPIN_RS27470"
                     /old_locus_tag="Cpin_5552"
     CDS             complement(8670..9062)
                     /locus_tag="CPIN_RS27470"
                     /old_locus_tag="Cpin_5552"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_012793146.1"
                     /translation="MRIPLTFIFLATIAMTGCSKKTTSGATEDCIKYSKVPVSQIDKAS
                     AGTSGKTTVYFQVNSGCGQFSKFIEKKSGNTITVEVEAVYKGCMCTMDIPTRQAAYQLK
                     EKAAGTYYLQFVSGENTFITDTVIVK"
     gene            complement(9163..11166)
                     /locus_tag="CPIN_RS37125"
                     /old_locus_tag="Cpin_5553"
     CDS             complement(9163..11166)
                     /locus_tag="CPIN_RS37125"
                     /old_locus_tag="Cpin_5553"
                     /inference="COORDINATES: protein
                     motif:HMM:PF02839.12,HMM:TIGR04183.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009087829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH19|CBM5"
                     /protein_id="WP_148230654.1"
                     /translation="MKTARFIVFLLLCCMSTAFSQSITDVITSAEWDVLFPHRFNPDDR
                     TGSGTLPTTAAKDFYSYANFREAVRLMSNIKIISERRCATNAYKLTRVDKTTGASVVIR
                     QDADFSVSPNAIIREEIDYATFAGEGDLIVRKRELMAFLANISQETTGGWPTAPGGQYA
                     WGLYFREEVGYEGTSNIGYREASTQYPPAAGKSYHGRGPIQLSWNYNYGQASEFIFGDK
                     NVLLANPEKVIQDGVIAFQTGIWFWMAQQYPKQSCHDVMIPGKWEPTAAQIAGGLKPGF
                     GATVNIINGGLECNKGTENTKVLSRIAHYQRYTGIKQVSMELNGGNNAVNCGCANMAPF
                     AIDNTECSQITALTFTSPANGILSVTSLSPVTLTVAKSDPKNEITQVFIKIGGLRLAGT
                     SIQWTPTAYGQQTATAVGLRNGKDSIVTTINFTVWNSQTFAGCASLPAWESTKIYEAAG
                     NIVRYNSVIYRNLWWAGSGDVPGTNSTWAVVGACNGNGGDGGGTGQPCGGVQGWTPGGI
                     YTQGVKVAYGNKIYQAKWWTQGDQPDTNTGDAKPWTFVSNCPVALAGAITTAAVLSQTS
                     ATENTLKVYPNPVNGNTLTVTIDGKGKERLLVSLLRAETGQPVLQQIVQPNGSGAQQVQ
                     LDISRVPSGTLILKVDSGRYGVMGTKKIIRIK"
ORIGIN
        1 atgaagaaaa aacgactttt ttcagtcctt gcctttacat gctgcataca ttttgcctat
       61 gcaggaaaaa tcgaaagact caaagacgga ttactggtaa ggttagaaaa aacaaccgcc
      121 ggaggagtaa aacaggtaaa actacaggtg atcacggata atattatccg ggtgaccgcc
      181 agtcctgcgg actccatttc caccactccc agcctgatgg ctatcgtcac cggtacccgg
      241 gaggtaaaat ggaccagcga agagaaaaac aaccagatca tactgaaaac cagcacctta
      301 actgccagca tcgatctgag taccggtgaa gtggtattta aagatgcaag cggccatgtt
      361 atattacagg agaaaaaagg aggtggtaag accttcacac ctgctattat agatggtaaa
      421 ccgctctata aactgcaaca ggtatttgaa tcgcctgctg gagaggcatt ttatggcctg
      481 ggtcagcacc agaccggtct gatgaactac aaagaccagg atgtagacct gacgcaatac
      541 aactcgatcg ctgtcatccc ctacctggtg tccagcaatc attatggtat cctctgggac
      601 aactactcca tcacccgctt cggggatgac cgtccttatg aagaattaac cagtctcgaa
      661 ctgacagaca aaaatggcaa accgggtggt ctcaccgcta cctatgccct ccggaataaa
      721 ccagacagca tcttcctcca aaaacaggaa tccgctatcg actttacttt cctgcctgac
      781 ctgaaaaaga tgcccgcggg tttcccgatg ggtaaaggca tcattacctg ggaaggcaat
      841 atcgcctcca aaacaggtgg ccaggagaag ttttatatga ccgcctccgg ctatgtgaaa
      901 gtatggatcg acggtgaact gaaactggat aaatggagag aaggctggaa ccctggtcct
      961 tccgtattcc gtcatcagct ggaaaaaggg aaacaacata agatcaaagt agaatggatc
     1021 ccggaatctg accaggcatt tgttgctgtc agacatctct ctcctacacc cgcctcttta
     1081 cagaataaag cggccttctc ctcagaagcc ggagagaaga tcgactacta ctttgtatac
     1141 ggtcagcaga tggatgatgt gatcaatggc tatcgcaata tcaccggtaa agccgccatc
     1201 gttcccaaat gggctttagg ctactggcag agccgtgaac gctataaaac tcagcgtgac
     1261 gtcatcagca ccgtacagga attccgtaaa agacagatcc ccctggacaa catcgtcatg
     1321 gactggtcct actggcagga aaatgcctgg ggtagccagg aatttgatcc cgcccggttc
     1381 ccggacgcaa aaggcatgat agactccctg cacaacatct atcataccca cttcatgatc
     1441 tctgcatggc ctaaattcta caaagacatt cataactata atctctttaa cgataaaggc
     1501 tggctgtata aacaaagcat caatgatggt atcagagact ggatcggaca aggttatgta
     1561 tctacctttt acgatgcttt caatcccggc gcacgtaaac tcttctggca gttactgagc
     1621 cggcacctct tcagcaaagg cgtagatgca tggtggctgg atgcaaccga accagacgta
     1681 ctctccaacg caaccatcga ctaccgtaaa caactgatga accctaccgc tttagggcca
     1741 tctacccaat attttaacac ctatgcactg ctgaacgcga aaggtattta tgaaggtcag
     1801 cgccaggaaa aacccgatca gcgcgtattc attctcaccc gttctgctta tgccggtatg
     1861 cagcgttatg cagctgctac ctggagtggt gatatcgccg cccgtttcga tgaactggcc
     1921 agacaaattc ctgcaggtct caactttggt atgtctggta tgccttactg gacgacagac
     1981 atcggtggtt tctatgtaga agacaaatac gatcaacctg atcccaaagg ggctgacctg
     2041 gaagaatgga gagagttaaa cacccgctgg ttccagtacg gcgccttctg tccgctgttc
     2101 cgctctcatg gtcaataccc ttaccgcgaa ccattcaata tcgcaccgga taacagtgtt
     2161 gaattcaatt caatggtcta ctacgataaa ctccgttacc gcctgatgcc gtacatctac
     2221 tccctcgccg gtcatactta ccacaatggt tacacgatca tgcgcggact ggtaatggat
     2281 ttcggtaaag acaccgccgt acagcgcatt ggcgatcagt ttatgtttgg tccgtcactg
     2341 ctggtcaatc ctgtctatac ttacaaagca cgccaacgtc agttatacct tcctgctaac
     2401 accggctggt ataacctgta tgacggtact tatacagaag gtggtaaaca tattaccgtg
     2461 gatgcgccgc tggacaggat tccgctgtac gcaaaagcag gtagtatcat tccgttcggc
     2521 cctgcgatgc agtacaccgc acaacgtcct gccgatacca tcacattgta tgtatatgcc
     2581 ggcagcaacg gcaaattcac cctctacgaa gacgagggca taaactataa ctacgaaaaa
     2641 ggacaataca gtaccattcc tttcacatac gacgacgcca gcaaaacact gaccatcggc
     2701 aaacgggaag gtaaattctc cggtatgctg caacagcgta cgttccgcat cgttcatgca
     2761 ggaaaagaaa aaccggtaag cctgaatctc gacaagctgg atgcgatagt gatgaagtat
     2821 gagggaacag aaaaaaagat atcacttaaa aattaaccac gtacatgaac aaagcaatag
     2881 ctaagcaata acactaacac gttgtgaatt gtaattcacg tttcgaccat cagacaaaca
     2941 catcccgtaa ctaacattct aacattatga aaactgctta caaaatcaga gattttgtga
     3001 ctgcctgcat gatccccgta tcatgcggat tgagcagcgc gctgctatta accatgttat
     3061 ccggcaacgt ggcaatggcg cagactccga aacgggcact ttccggtaaa gtgaccacag
     3121 gtaaagataa cagcccgctt cccggcgcca gtgtacgcat caaaggcacc aacaacggcg
     3181 ccattacaga tggtacaggc agcttcaatc tacaggtagg cgacgccgac tcgctcgaag
     3241 ttacacttgt aggtttcacc agacaagtca tctccgcaag aggaaaatcc tccctgacgg
     3301 ttaatcttag tgaaggctcc accggccttg atgaaatcgt agtagtaggg tacggtaccg
     3361 aaaagaaaaa actggttacc ggcgctatcg atcacgtaaa cacacaacag ctggaacaaa
     3421 accatgccct gcgcgtggac caggcattac agggacaaac gcccggcgta cagatcaccg
     3481 ctacctctgc tcaaccgggt gaaagcatga aagtacgtat ccgtggtaca agtactgtcg
     3541 gtaatgcaga tccgctgtac atcgtggatg gtgtacccac atatgatatc agctacctga
     3601 atgcttccga tattgccagc atggacgtac tgaaagatgc cgcatcttcc gctatctatg
     3661 gtgcaagagc agcgaatggc gtagtattga tcactacacg taaaggccgt gcaggtacca
     3721 tgaagatcgc ctacgatgcc tactacggta cccagaaccc ttctcataaa gtatctgtac
     3781 tcaatgcaca cgactatggt gtgatcatga atgagatggc catcaattcc ggtggtcagc
     3841 catacttcac catagatcag ctgtcaaaac tgggtaaagg caccgactgg caggaagcta
     3901 tctataataa gaatgcacct atgcagaatc attccctgag cttcgctggt ggtaatgatg
     3961 catctgtatt ctcttcctct atcgcatata ccgaacaggc agggatcatc ggtgtaaatg
     4021 atcagtccag gtatgacagg ctctctttcc gcatgaacag cgagcataaa atgtacaagg
     4081 acatcatcat cttcggagaa aacctgacct atacacaatc gcgcaaaaga ggcatcggtg
     4141 taggcaatat ctataacaac gctatccgct ccgtattcag taccagtccg ctgttccctg
     4201 tatacgacga gaacggcaac tacgcaaagt cttcctttaa cgtagaagaa gccaatccgg
     4261 tagcattgat ggattaccag aaccagaaca aggataaaac aaaccgtatc atggggaata
     4321 cttacttaca gatatctcct gtcaaaggtt tgtccatccg tactgacttt ggtatcgata
     4381 tcagcagtac cgattccaga agctatacac cgctctataa cctgtccacc aatgtgatca
     4441 acgaacactc ccgtgcaaca cagggtattt atcgtaccaa ctcctggaac tgggataata
     4501 ccattaacta tcagcgcgac ttcggcaaac acaatatagg tgtactcgta gggatgaacg
     4561 ccaatgaaac aaaagcaaat tatctttacg gatataagca ggacctgacc aaaaccggtc
     4621 tggataatgc ggtgatcgat aatggtacga cagacagtac acaacgcatc tacggtgcag
     4681 acagcgctgc caccatctat tcttacttcg gacgtatcag ctactcatac gcagataaat
     4741 atatgttcac cgctgtagta agatcagatg catcttcccg cttcggtccg aacaaccgca
     4801 gggcttactt cccgtccttc tccgtgggtt gggtaccgac caatgaagac ttcttcaaac
     4861 ctacctggct ggagttcctg aagatccgcg caggctgggg ccagaacggc aacctgccta
     4921 ccggctatta ccaatacctg tctaccattt ctacacaata cctgggttac tatttcggca
     4981 gcggagacgc acctgctatc ggcgcagcgc ctatcaaaat atctaatccg gacctgaaat
     5041 gggaaacttc cgaacaggcg aacatcggct ttgatgcgaa cttcctgaaa gacttcaacc
     5101 tgactgttga catctaccgc aagaccacca aagactggct cgtacctgtc aatgtacctg
     5161 ctgtatcagg tgctgcaaca gtgctgatca atggtggtga tgtacgcaac cagggtgtgg
     5221 agatctctct cggttatcac cacactttcc atgacctgag tgtaggtgta aatggtaata
     5281 tgggcatcaa ccgtaacgag atcactgaca ttcccaataa agaaaagatc atcaacggcg
     5341 ctaccgctat tacctaccct agtatgcctg aattctaccg cgcacaggta ggtttcccga
     5401 tgggttattt ctacggatat aagaccgctg gtatcttcca gaatgaccag gaagtggcag
     5461 cgtacgtatc caaagatggc aagaaaatac agccgaatgc acagccgggt gatgtacgct
     5521 tccaggacct gaatggcgac ggcgtaattg atagtaaaga tcagacacag atcggtaacc
     5581 cttatcctaa attcacctac ggtctgaaca tcaacctggg ttataaagga tttgatttct
     5641 cggcttcttt atatggtaac tacggcaacc agatctggga tggtacacat gacttctccc
     5701 gtccgctgag taattacacc actgaaatac tcggccgctg gactggcgaa ggcagttcca
     5761 accgcctgcc tcgtgtcact gatggcgcag aactgaacca gaactggatc cgttcttccg
     5821 acctctatgt acacaatgcg tccttcctgc gtgttaagag cctcaacctg ggatacgatt
     5881 tcaaacagct cttacataca ctgccgctgg gacagttgag attatacgtt tctgctacca
     5941 acctgttcac cttcacacct tacaaaggtg tagatcctga agtaggttac ggtcctacag
     6001 gatgggcttc cggcattgac ctgggaacct atccgcagcc aaaatccgta ctggtaggtc
     6061 tgaacgttaa attctaatcc ggtaaatcat tccacatgaa aaagatcttc gcttccatta
     6121 tagctatctc actctttgct gcctgcagca aggatttcct ggagcgctct cctgttgacg
     6181 aacagacaga aacctccttt tatcagactc ccgatcaggc cctgcaggca ctggtagcag
     6241 tgtacaatca gcttaacatc ggcgactatg ataatattca cctcgtgtca gaactggcca
     6301 gtgacaattg cttcggcggt ggtggtacct ctgacctcgt ctggaaacaa tgggatcgct
     6361 tccaggaagc atccaatatg aacctgggcc tctggcagaa atactatacg ggtatctaca
     6421 gagcgaatgt attattgtct aaaatagatg gtgtcaactg gggtactgac agtacactga
     6481 aaaacaccta cgtcgcagaa gcacgcttcc tcagagctta cttctatttc gacctggccc
     6541 gcttcttcgg aaatgttcca ttagccacca aaccgctgac cgtatcagaa tacaacatgc
     6601 cgcaggctac gccggcggat gtatacaaac agatcgcgga agacctgaaa tatgcagcgg
     6661 agaaattacc tgctgtggcc tatcagggta ttccaacctc taactacggc cgcgtaacca
     6721 aatgggcggc acaggcatta atcggtcgtg tattcctcta ttataccggc tattataacc
     6781 agaatgacct ggcaggtgtc gtgactaaag cacaggcagc cagttacctg gaaaatatca
     6841 tcaatgcagg tggctatgga cttgtagaca gcttcccgcg tttatggcag gcttctgctg
     6901 cttcctttgt tggtgaagac aataaagaaa cgatctggtc gatcaagttt acgcataaag
     6961 gactgggtaa ctgggatcag cacaatggta accgtatgca ggtagatatc ggcatccgta
     7021 gccaggtact gaatccttac tacaaaggat ggggcgccgg taccgtgaac agcaaactgt
     7081 ggaatgccta cgatggcgct gacaccagga gaaatgcctc tatcatctct attgaagatg
     7141 aaaacctgac agcatatgca atcggtgatc agtcacaata taccggctac ttctggaaaa
     7201 aatatatgcc acttaatgat ggcaatgcgg atagcaaagg tggtaatttc cagatcgaca
     7261 actattttga tgatgttatc atccgttatg cagatgtact gctaatggca gctgaactga
     7321 atctgggtac tgatctgggc aaagcgcagg ggtattacaa ccaggtgcgt gacagggctt
     7381 tcctgaatac caccagcaga aaaacgctga ctgctaccaa cggtaaaagc ctgatcatgg
     7441 aggagcgcag actggaattt gcactggaag gtttacgcta ctgggacctg ctgcgccagg
     7501 gtatgagcgt agcaaaagct gctatcgaca acagcagttc agatgcacag ttcaatgtct
     7561 ctttccgtac agaaacacag ggacttttca aaataccaga gcaggagatc aatctctcca
     7621 gcggcgttta cagacaaaat ccaggatggg ctaactaatg ttgaatcatt ccacaaaaaa
     7681 ctgcatcatg aaaaagttta tcaccttatc cctgctcgcg ttatctgcac tgctggtttc
     7741 ctgtacaaag gaggatgaag aaagtctgga tggaccaagc atatcaaaag ataacctgaa
     7801 attttccgtt acacaggaac agggacacga caatatcgtt atgctgaaca gcctcacagc
     7861 aggtagctat atcccattct gggaatatac cggcggcttt tcaaagaata agaaggatac
     7921 aatcaacctg cccttcgcag gcaagtatac catccgctat acgatctata cacccggcgg
     7981 accattagct gattccagcg atattaccgt gtcaaaaaat gacccggaat attttgccag
     8041 tccgctatgg aaattgctta ccaacgaaca gaccggtaag acctgggtat gggcgacaga
     8101 tatccctggt ggtatctgtt atggtaacgg atccggtggc gcaacagcgc ctgaatggtg
     8161 gcagaatggt atcgcttacc tgacagaaca gggcgttgct gccgacgaga tgaccttcga
     8221 tctcaatggt gctaaaaact actcactcac acatgccggc acagcaaaaa aggcattgtt
     8281 tgagctggac acattgaaca gaactttaaa gataacaggt gcagatattc cgctcggcgg
     8341 aaaagtgact tacgtgatcg taaaactgac cgctgatgaa ctgacccttg cacagcaagg
     8401 cgatggctgg agaaacatct ggatgtacaa aagaaaggga tttaactatt agttttcggg
     8461 atttaagatg gaagaaaaaa gggatgaggt tttgcacctt atccctttaa aaaaattagg
     8521 aattaagaat taggaattaa gaattgtata accacaagga acactataat cagactcgtt
     8581 tattatataa gctattaaaa tagtaaccta tttaagtatg ctgtacaata ttgccaaaaa
     8641 ttcctaattc ttaattccta attcctaatt tatttcacga tcacagtatc tgtaataaac
     8701 gtattctctc ctgatacaaa ttgcagataa taagtgcccg cagccttttc ttttaactga
     8761 taagcagcct ggcgggtagg aatatccatt gtacacatac atcccttgta aacagcttct
     8821 acttctaccg tgatcgtatt accgctcttc ttttcaataa atttactgaa ttgtccgcag
     8881 ccactgttca cctggaaata aacggtagtt ttaccgcttg tacctgcaga tgctttgtcg
     8941 atctgactaa caggcacttt actgtatttg atacagtcct ctgtagcgcc ggaagttgtt
     9001 tttttactgc atcctgtcat ggcaatcgtc gccaggaaaa taaaggttaa tggtattctc
     9061 atgaaaattg atttataccc ctctcctaaa aacggaaagg gaactgtaac cttaacgcat
     9121 aagatatgcc attggttaca gttccctcaa aaatttaata ttttatttta tgcggatgat
     9181 cttcttagtg cccattacac catatctgcc gctgtcaact ttcaggatca gggtaccgga
     9241 aggtacacgg ctgatatcca gctgtacctg ttgggcccca ctgccatttg gctgaacgat
     9301 ctgctgtaat accggctgac cggtttcagc acgcagcaat gataccaaca gtctctcctt
     9361 gcctttaccg tctatggtca ccgtcaatgt gttgccattc accgggtttg gataaacctt
     9421 cagcgtgttt tcagtggctg atgtttgact gagaaccgcc gctgttgtta tcgcacccgc
     9481 caaagctacc ggacaattac ttacaaaagt ccagggtttc gcatctccgg tattggtatc
     9541 cggctgatcg ccctgtgtcc accattttgc ctgatagatc ttattgccat aagccacttt
     9601 cacgccctgg gtatagatac cgcctggcgt ccatccctgt acgccaccac atggctgacc
     9661 ggtaccaccg ccatcgccgc cattaccgtt acatgcgcct acaacggccc aggtgctgtt
     9721 agtacctggt acatcgccgc taccagccca ccataggttg cggtagatca cgctgttata
     9781 acgaacgata ttgccggcag cttcataaat cttcgttgat tcccaggctg gcagagaagc
     9841 acaaccggcg aaagtctggc tgttccatac cgtgaaattg atggtggtca cgatggagtc
     9901 cttaccattt ctcagcccga cagcagtcgc cgtttgctga ccataagcag tcggcgtcca
     9961 ttgtatgctg gtacctgcca gcctcagacc gccgattttg atgaatacct gggtgatctc
    10021 attcttcgga tcgcttttcg caaccgtcag tgtcacagga gacagggaag tcacactgag
    10081 aataccattc gcaggagaag tgaaggtcaa tgccgtgatc tgtgaacact ccgtgttgtc
    10141 gatggcaaaa ggagccatat tcgcgcaacc acagttaacc gcattattac cgccattcag
    10201 ctccatgctt acctgtttga taccggtata acgctgataa tgcgcaatac ggctgagtac
    10261 tttcgtgttc tctgttccct tgttacattc cagtccgccg ttaatgatat tcaccgtagc
    10321 gccaaaaccg ggtttcaggc caccggctat ctgtgcagca gtaggttccc atttaccagg
    10381 gatcattaca tcatggcagg actgtttggg atactgctgg gccatccaga accagatacc
    10441 tgtctggaaa gcaatcacgc catcctggat cactttctcc ggattagcga gtaatacgtt
    10501 cttgtcaccg aagataaatt cacttgcctg accgtagtta tagttccagc ttaactggat
    10561 cggaccacgg ccatggtagg atttacccgc agcaggcgga tactgtgtgc tggcttcgcg
    10621 gtaaccgatg ttgctggtac cttcataacc tacttcttcg cggaaataca atccccaggc
    10681 atactgaccg ccaggtgccg taggccagcc accggtggtt tcctgggaga tattggcgag
    10741 gaatgccatc agctcccttt tacggacaat caggtcgccc tcgcccgcaa aggtggcata
    10801 atcgatctcc tcgcggataa tagcgttagg agaaacgctg aaatccgcat cctgacggat
    10861 taccactgaa gcgccggtgg ttttgtccac acgggtcagt ttgtaggcat tggtcgcaca
    10921 acgtctttca gaaataatct tgatgttgga catcagtctt acggcttctc tgaaattggc
    10981 gtaagaatag aaatccttcg cggctgtagt gggtaaagta ccactaccgg tacggtcatc
    11041 aggattaaaa cgatgtggaa ataaaacatc ccattcagca ctggtgataa catcagtaat
    11101 cgattgggag aaagctgtgg acatacagca tagcaatagg aagacaatga aacgtgcagt
    11161 tttcat
//
