LOCUS       NC_013132              14656 bp    DNA     linear   CON 26-AUG-2019
DEFINITION  Chitinophaga pinensis DSM 2588, complete genome.
ACCESSION   NC_013132
VERSION     NC_013132.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN00001914
            Assembly: GCF_000024005.1
KEYWORDS    RefSeq.
SOURCE      Chitinophaga pinensis DSM 2588
  ORGANISM  Chitinophaga pinensis DSM 2588
            Bacteria; Bacteroidetes; Chitinophagia; Chitinophagales;
            Chitinophagaceae; Chitinophaga.
REFERENCE   1  (bases 1 to 14656)
  AUTHORS   Glavina Del Rio,T., Abt,B., Spring,S., Lapidus,A., Nolan,M.,
            Tice,H., Copeland,A., Cheng,J.F., Chen,F., Bruce,D., Goodwin,L.,
            Pitluck,S., Ivanova,N., Mavromatis,K., Mikhailova,N., Pati,A.,
            Chen,A., Palaniappan,K., Land,M., Hauser,L., Chang,Y.J.,
            Jeffries,C.D., Chain,P., Saunders,E., Detter,J.C., Brettin,T.,
            Rohde,M., Goker,M., Bristow,J., Eisen,J.A., Markowitz,V.,
            Hugenholtz,P., Kyrpides,N.C., Klenk,H.P. and Lucas,S.
  TITLE     Complete genome sequence of Chitinophaga pinensis type strain (UQM
            2034)
  JOURNAL   Stand Genomic Sci 2 (1), 87-95 (2010)
   PUBMED   21304681
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14656)
  AUTHORS   Lucas,S., Copeland,A., Lapidus,A., Glavina del Rio,T., Dalin,E.,
            Tice,H., Bruce,D., Goodwin,L., Pitluck,S., Kyrpides,N.,
            Mavromatis,K., Ivanova,N., Mikhailova,N., Sims,D., Meinche,L.,
            Brettin,T., Detter,J.C., Han,C., Larimer,F., Land,M., Hauser,L.,
            Markowitz,V., Cheng,J.-F., Hugenholtz,P., Woyke,T., Wu,D.,
            Spring,S., Klenk,H.-P. and Eisen,J.A.
  CONSRTM   US DOE Joint Genome Institute (JGI-PGF)
  TITLE     The complete genome of Chitinophaga pinensis DSM 2588
  JOURNAL   Unpublished
REFERENCE   3  (bases 1 to 14656)
  AUTHORS   Lucas,S., Copeland,A., Lapidus,A., Glavina del Rio,T., Dalin,E.,
            Tice,H., Bruce,D., Goodwin,L., Pitluck,S., Kyrpides,N.,
            Mavromatis,K., Ivanova,N., Mikhailova,N., Sims,D., Meinche,L.,
            Brettin,T., Detter,J.C., Han,C., Larimer,F., Land,M., Hauser,L.,
            Markowitz,V., Cheng,J.-F., Hugenholtz,P., Woyke,T., Wu,D.,
            Spring,S., Klenk,H.-P. and Eisen,J.A.
  CONSRTM   US DOE Joint Genome Institute (JGI-PGF)
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2009) US DOE Joint Genome Institute, 2800 Mitchell
            Drive, Walnut Creek, CA 94598-1698, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 08/26/2019 00:28:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
            Annotation Method                 :: Best-placed reference protein
            Annotation Software revision      :: 4.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
            Genes (total)                     :: 7,171
            CDSs (total)                      :: 7,077
            Genes (coding)                    :: 7,009
            CDSs (with protein)               :: 7,009
            Genes (RNA)                       :: 94
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 19 of 68
            Pseudo Genes (incomplete)         :: 47 of 68
            Pseudo Genes (internal stop)      :: 11 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
            ##Metadata-START##
            Organism Display Name :: Chitinophaga pinensis UQM 2034, DSM 2588
            Culture Collection ID :: DSM 2588, ATCC 43595, LMG 13176, UQM 2034
            GOLD Stamp ID                     :: Gi02244
            Funding Program                   :: DOE-GEBA 2007
            Gene Calling Method               :: Prodigal
            Isolation Site                    :: Pine litter in Australia
            Isolation Country                 :: Australia
            Oxygen Requirement                :: Aerobe
            Cell Shape                        :: Rod-shaped
            Motility                          :: Motile
            Sporulation                       :: Nonsporulating
            Temperature Range                 :: Mesophile
            Temperature Optimum               :: 23 - 24C
            pH                                :: 7
            Gram Staining                     :: gram-
            Biotic Relationship               :: Free living
            Diseases                          :: None
            Phenotypes :: Biomass degrader, Chitin degradation
            Energy Source                     :: Chemoorganotroph
            ##Metadata-END##
            REFSEQ INFORMATION: The reference sequence was derived from
            CP001699.
            URL -- http://www.jgi.doe.gov
            JGI Project ID: 4082984
            Source DNA and organism available from Hans-Peter Klenk at the
            German Collection of Microorganisms and Cell Cultures (DSMZ)
            (hans-peter.klenk@dsmz.de)
            Contacts: Jonathan A. Eisen (jaeisen@ucdavis.edu)
            David Bruce (microbe@cuba.jgi-psf.org)
            Whole genome sequencing and draft assembly at JGI-PGF
            Finishing done by JGI-LANL
            Annotation by JGI-ORNL and JGI-PGF
            The JGI and collaborators endorse the principles for the
            distribution and use of large scale sequencing data adopted by the
            larger genome sequencing community and urge users of this data to
            follow them. It is our intention to publish the work of this
            project in a timely fashion and we welcome collaborative
            interaction on the project and analysis.
            (http://www.genome.gov/page.cfm?pageID=10506376).
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Annotation Pipeline (PGAP)
            set; GeneMarkS-2+
            repeat_region
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..14656
                     /organism="Chitinophaga pinensis DSM 2588"
                     /mol_type="genomic DNA"
                     /strain="DSM 2588"
                     /type_material="type strain of Chitinophaga pinensis"
                     /db_xref="taxon:485918"
                     /note="type strain of Chitinophaga pinensis"
     gene            complement(1..3123)
                     /locus_tag="CPIN_RS13565"
                     /old_locus_tag="Cpin_2720"
     CDS             complement(1..3123)
                     /locus_tag="CPIN_RS13565"
                     /old_locus_tag="Cpin_2720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012790133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH2"
                     /protein_id="WP_148230767.1"
                     /translation="MTGSSYAFQQIQLQHGPWHSKTDTATVPKEIEDPECLGINKEPAH
                     ATLMPYADLKEALNANRYASSFSKSLNGTWKFNYVPWPQQRPVDFYKPDFSVEKWADIK
                     VPSCWQVEGYGTPYYSNFNYIFQKDFPRVMSTPPVNFTAYKERNPVGSYRRNFDVPADW
                     DGRRIFITFDGVDAGFFLWVNGHKIGYSVNSRNAAEFDITEFVKPGANIIAVEVYRFTT
                     GSYMEDQDMFRLSGIFRNVTLWSAPQEHIRDFLISTDLDANYVHATLNASGKIKNYGTT
                     KTPARKVSVELYDGTKLIKSGTADVSALQPGEEASWKVAFPVYNPRKWTAETPALYTTV
                     VTALDGKKVIETMSSRTGFRKIEIKGRVFMVNGVAVKLKGVNRHENWPETGHTVSEPDM
                     VRDILLIKQANCNHVRTSHYSNDPQWYELCNEYGLYLLAEANVESHGAWDEFNEDPRIK
                     AAIIDRNISNVENFKNHPSVIIWSLGNECGSGGTNFRAALAAIQKLDPTRPTHYQGFGT
                     GDKNPSDMDSEMYTQLHEVRRHATEPGLTKPFYLCEYAHAMFNSMGSVEEYSDLFDEYP
                     ALLGGCIWEWEDQGIWNRIDPQHPIIAYGGGFGEWPNDRFFIHKGVVFSDRSVKPHYPE
                     LKHAYQWIKVKPVDIARGKLRILNKYQFITLNGYNASWTLMKNGVITDSGKIMLPPVAA
                     GDSADVQLPRFTKRTSNAEYIVRLSFKLTNEESWAHKGFEVASQQLEIPGGNGDFTGIM
                     QKGPLAVKEADNDIEIDGSNFSLVFNKQKGTFTSIKSKGQEMLETNGGPLLHLWRAPHR
                     NDDMWADDEWERYGLKRMEWSASDIAIKNEGDITITATLNGKGRNGFTVNHQVSYVISG
                     DGVVKVNNNLSFGTVNIPLARVGVRLLLKSNLDKFQYYGRGPEENYADRKSGEDVGIWG
                     SSVKAQLTPYEKPMECGNHEDVRWATVRSNEASLSVVKTKDLLQVSALPYRDEDLQHVE
                     YRIDLPESKLTALCISTHTLGVGSNSCGPRPLDRFVPRAVSQSFSYVLKIQ"
     gene            complement(3258..4937)
                     /locus_tag="CPIN_RS13570"
                     /old_locus_tag="Cpin_2721"
     CDS             complement(3258..4937)
                     /locus_tag="CPIN_RS13570"
                     /old_locus_tag="Cpin_2721"
                     /inference="COORDINATES: protein motif:HMM:PF07980.9"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RagB/SusD family nutrient uptake outer membrane
                     protein"
                     /protein_id="WP_012790377.1"
                     /translation="MQYKYNSYGHVLVLALLIFITSACKKDGFLNVDPKGSLTDESTFA
                     TEANADLFVNDIYDQLPDMNNESQLLDQWTDNSCVGATWMTGQSLIRSNALNPSNAPDG
                     PGAMFKWSENYSRIRRCNVFLQQAAKYRDHFSDEWYQQRVAEVKFLRALFYSFLYQNYG
                     GVPLISEPLNNQTMGDKIFIPRASMEETLAFIEADCDAAAADLPTKAAATGRATKGAAL
                     TLKGAVDLFAASILVNTNNDPARWAKAAAANKAVIDLNVYDLFPDYNGQFLAANNWNIE
                     TIFARGYAVPSKGHRREGMQGPVIVHGVQQAWGNLEPTQNLVDDYEMANGLPITDPASG
                     YDPQQPYVNREPRFYATIVYDGSTWQGYTFLSRVGGNNQIDLGSSSDISNTGYNGKKTL
                     DESILGQTSLGIYPGTSNYIFYRYAEVLLNYAEAQNEATGPDASVYSAINSVRRRAGLP
                     ALPAGMTQTEMRINIRRERRIELAFEDKRWYDIRRWDITTKGEAVLTHPQYGMKITTEA
                     NGRLTYTKVPIFNSTFSQHMNWLPIPQSAMEQNTRLTPNAGY"
     gene            complement(4949..8086)
                     /locus_tag="CPIN_RS13575"
                     /old_locus_tag="Cpin_2722"
     CDS             complement(4949..8086)
                     /locus_tag="CPIN_RS13575"
                     /old_locus_tag="Cpin_2722"
                     /inference="COORDINATES: protein motif:HMM:TIGR04056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gnl|TC-DB|Q45780|1.B.14.6.1"
                     /protein_id="WP_012790378.1"
                     /translation="MKRTPTDGNSFNKRWLSGVTLLLILFLPLLSLGADITVAGLITDA
                     SGQPIPGASILIKGTNTGTQTDAIGHFTLKAPDKATLVVSFLGYESQQIPVAGRAVINV
                     QLQESAKVLNDVVVVGYGTQKRTSLTAAISTIKTAEIANKPVVNLSNSLVGRVSGLIAT
                     QGSAEPGFDASNIQIRGAGSIGSTAPLLIVDGVPRDFSRLDPNTVATFTVLKDAAAVAP
                     YGVAGANGVILVTTKTGKAGKPTLAYNGYYGFQNPTRVPKFVNSYQYAMLRNEANANDG
                     QPAAYSAEDIQKFRDHSDPDGHPDGHPLDDIIKPNRPITYHNLSLSGGGSDYQYFASVG
                     YQHQDGMWSTTYLNKYMANLSLTANVTKTTKVSLMANGYVEDQHFPATGAGSILDQAMR
                     QAPTTPVYYSNGLWTGYIGQSLIGEIYHSGYHLSENSSLITQLSIDQQLPVKGLSIKAV
                     VSYDNGPDPIFNNKTSFQREYRTPIPFWNVDTTKRPYEYVKGIQGNSKAQFYEDFSMNK
                     ALTYQGMLNYIGHFGKSDITALAVVENRSVKYQTFRAQRINYNLDIDELNFGGPAASDA
                     TSSGLSNGQRQLGYVYRIGYSYDNKYLFEAAGRYDGSYLFAPGNRFGFFPAFSAGWRIS
                     EEAFMKKITWIDQLKLRGSWGESGAYPSSGGSIQTYQYLSPYNVNGNSAVIGGNTTQGI
                     KEALQGNPDITWERARKTDIGFDISLWKGLLSIEADYFSEKRSNMLVGIGNSLPAEYGI
                     GVGLINAGIMQNRGIDLSLGSSKTFSNGLRLDVTGTFTYARNKLLKVYENDATYKNVNR
                     RQTGRPNGTQFGLQAIGYFQENDFNSDGSLKAGIPVPSFGNVKAGDIRYADLLGPDGKP
                     DGRIDANDITRIGYSSTPEIIYGLEPRLSYKGFDVDLLFQGSGHSSLYVSQYFVWPFQS
                     SGSATELAYEDHWTPTNTDALYPRITGAPTANNTQQSSWWMRNTSYLRLRSAELGYTFS
                     SKTLGHSISSLRLYVSGQNLFTWTPHIREILDPENNSSNMNYFQQRVITFGINATF"
     gene            8381..12457
                     /locus_tag="CPIN_RS13580"
                     /old_locus_tag="Cpin_2723"
     CDS             8381..12457
                     /locus_tag="CPIN_RS13580"
                     /old_locus_tag="Cpin_2723"
                     /inference="COORDINATES: protein
                     motif:HMM:PF00072.22,HMM:PF00512.23,HMM:PF07495.11"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DBD-Pfam|HTH_AraC,DBD-SUPERFAMILY|0035607"
                     /protein_id="WP_148230565.1"
                     /translation="MKVLLSGLIMLMTTRQHVLGQSYPYHFNALTVDEGLSHTDATDIV
                     QDRWGYIWVSTLFGINKFDGYNVRRYYNSNIPLNNAYRNRVICMAVDSTGFLWLGTEAG
                     FQRFDTRTSQYIDYPVSQGSSANDLTKIVISSSHTFYALASKDQLRCYLLKGTTLQEKK
                     LHLPEGVGISDIAMDVGGQLYLATTSGLWVLGENGIAHMIKVAGCAENHFSKLFIDQNR
                     HLLLATGERLYLVQTVGDYPSVVKTAAIRGEVSDMVQEAGGNYWINSSQRLTRLDKNLV
                     FVQEINNESPIKYVDLSGLQSLFIDKSQCIWTVSFGNGVQYADLNEKKFYTLQHLPETP
                     YSLSGSYVRAILDENGKDLWVGTSDHGLNHYDLQKQQVVQVYNNYNSTVRLPENTITAL
                     ATDNEHNLWIGGQSGITVMRPNRQELWRPPGAENFPAHVIDVLAKDCFGNIWFGDHTHK
                     FGVIFKDAVGKYHVKEYGESFFIHADSVKPQLMISSTHGLKRLIIDKEGNIVKSWSYEA
                     TGKPNSLSSNYTYPIAKQNDSIYWIGTIGGGLNRIILRADDTYAITQFTKGVFKDVEGL
                     EVDDKGFIWLAGNGLQRLDPRTGAVIRYDKKDGLQGNSFKVNSSCRGANGMLFFGGING
                     LNYFQPLEITANPIAAVPQISRLSVNNEAADSARYITNVAAVRLNYLQNNFVIFFSAMH
                     YANPLKCRFRYMLKGYDHVWQYTDGNHASAAYSNLDFTEYKFIVEASNNDGVWNSQQAS
                     VTIIMIPPWWKSFPAKLFYILLIMAVLVGIYIYQARWYRLKNELLLRAVAERQREDIHQ
                     QREQMYQQQLQLFTNISHEFRTPLTLIRGPLEYLISHDGQSTHLHAYQLMLRNVKRLIN
                     LVSELMNFKKVADGAIRLQVQPMSIDEFCQSLYTEFGALAESKNIAFNITGDIGQRDII
                     SYFDAQVLEKILLNLLNNAFKYTSNGGKVTMQYFLDEDKFKPSFDTGFRLPNEFKASKY
                     IYFLVSDSGIGISEASIQSIFDRYYRVSNHHLGSGVGLALVKSLTQLHKGEIAVFSERN
                     KGTEFLVALPWGKENYSAGEIIEPGSMSGSQLEQLDSPTPLLSKPVPTAPMSTRKARHI
                     LLVEDNQELRTFLRESLEPYYHIHEAADGNSAMTIATELNPDLIISDVMMPGGNGIDLC
                     KHIKQTFETSHIPFVILSARDGLETKIEGLKSGADYYFAKPLNMSLLLLTINNIFEQNS
                     KLKQRYTKDHLIEATELVHSEKDKDFMNTLLQIIEENIQNPELEVEFLCMRMNISRTKL
                     YQKIKGISGQSVGEFIKTIRLKQAIYIMTHEDITLSEVADRIGLQSSSYFSRMFKKEYG
                     STPSEFVKGLRNASK"
     gene            13049..14656
                     /locus_tag="CPIN_RS13590"
                     /old_locus_tag="Cpin_2725"
     CDS             13049..14656
                     /locus_tag="CPIN_RS13590"
                     /old_locus_tag="Cpin_2725"
                     /inference="COORDINATES: protein motif:HMM:PF03663.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH76|CBM13"
                     /protein_id="WP_012790380.1"
                     /translation="MKTLKSNLFGVAVTFASVLLLLSSCKKAEQSLPVDKLDLTTKSAA
                     NALLLVEANPNADAAFNSFNSSFLVSSGTTQYYKEALNVSGKDYFWRQALDIQMVEDVY
                     LRTQSSAHRTLITNMLNTFLQQNQGSGGLYDWNWNDFNDDLQWAGIAFARGYQITGNTT
                     YLNQAKYAFDRSYNRGWTTELGGGVWWDVNHESKSGLSNNPEMILGCYIYEATKDIGYL
                     NKVIAIYNWVKATLYNSATGAVYENIRPDGTVSADANVYNIGAFVSAANHLHRLTGNAV
                     YYDDAKRSVDYVRNNKTVNGIMTNGQRQGTWQSEFIRGLGEFVRDNNLWSTYYTWMKQN
                     ADAAWNIRRTDRNLMWNNWTTTTPSDNVTTAVECIGGVIMQQITPTTQPTGITNNSVYR
                     LIPKINENSALDIAGSASGSLAGIWDWNNGLNQKFRMVSLGYGYFRLVPQHNTGTSLDV
                     TGGSAENNTPIEIWTSNNNSSQAFKVVYDYHGYYKLKPKCAPSSCVNVAGANPANGTKC
                     VLWPESNVDQERFALAVQ"
ORIGIN
        1 ttattgtatt tttagtacat aagaaaaaga ttgtgacaca gcacgcggca caaagcggtc
       61 aagaggacgg ggaccacagg agtttgagcc tacacccaaa gtatgtgtgg atatgcaaag
      121 cgccgtaagt ttgctctccg gcaagtctat gcgatactca acatgctgca gatcctcgtc
      181 gcgatacggc agggcagata cttgcaggag gtctttagtt tttacaacag acagtgaagc
      241 ctcattgcta cgcacagtcg cccagcgcac atcttcatgg ttaccgcatt ccatgggttt
      301 ttcgtaagga gtgagttgcg cttttacact gcttccccag atacctacat cttcgcctga
      361 tttacgatca gcatagttct cttcagggcc acggccataa tactgaaatt tatccagatt
      421 actttttagt agtaatctta caccaactct tgcgagtgga atattcacag ttccaaagct
      481 gaggttatta tttactttta ccacaccatc accgcttatt acataggaaa cctggtgatt
      541 tacggtgaag ccgttgcggc cttttccatt tagtgttgca gtaatagtta tatcaccctc
      601 attttttatt gctatatcgc ttgcgctcca ctccattctt ttaagaccat agcgctccca
      661 ttcatcatcc gcccacatgt cgtcattgcg atgaggggca cgccataaat ggagtagggg
      721 gccaccgttt gtttccagca tttcctgtcc cttgcttttt atcgaggtaa aggttccttt
      781 ctgcttatta aaaacaagtg aaaaattact gccatcaatc tcgatatcat tgtcagcttc
      841 ttttactgca agtgggcctt tttgcataat gcctgtgaag tcgccattcc cgccaggtat
      901 ttccagttgc tgtgaggcta cttcaaaacc tttatgcgcc cagctttctt catttgtcaa
      961 tttgaaagaa agtcgcacaa tatactcagc atttgatgtg cgcttagtga atctgggtaa
     1021 ttgtacgtca gcagaatcgc ctgctgcaac aggcggaagc attatttttc cgctatcggt
     1081 aataacacca tttttcatca acgtccagct ggcattatag ccattcagcg tgataaattg
     1141 gtatttgttc aatattcgta atttaccccg ggcaatatca actggtttaa ctttaatcca
     1201 ctgatatgca tgttttagtt ccgggtaatg aggcttgaca ctgcggtcag aaaatactac
     1261 gcctttatga ataaagaaac ggtcgtttgg ccattcacca aaacctccgc cgtaagcaat
     1321 gatggggtgt tgaggatcaa tacggttcca gataccctgg tcttcccatt cccagataca
     1381 accgcctaac aatgccggat attcatcaaa caagtcgcta tattcctcta cgctgcccat
     1441 cgagttaaac atcgcgtgcg cgtattcgca gagatagaat ggtttggtca ggcctggttc
     1501 agtagcgtgg cgacgtacct cgtgtaattg cgtatacatc tcgctgtcca tatcactggg
     1561 gtttttatca cctgtgccaa atccctgata gtgcgtaggg cgggtgggat ccagcttttg
     1621 gatcgcggcc aatgctgcgc ggaaattggt gcctccgcta ccgcattcgt tgccgagaga
     1681 ccagataatg actgaaggat gatttttgaa attctccaca ttagagatat tccggtctat
     1741 gatagccgct ttaatgcggg gatcttcatt aaattcgtcc catgcgccgt gtgattccac
     1801 attcgcctct gcgagcaggt agaggccgta ctcgttgcat agctcatacc actggggatc
     1861 attggagtag tgtgacgtgc gcacgtggtt acagttagcc tgtttgatca gcaggatgtc
     1921 ccggaccata tcgggttcag acactgtatg tcctgtttcc ggccagttct cgtgacgatt
     1981 tacacctttc agttttactg caacaccatt taccatgaat acccttccct tgatttctat
     2041 tttacggaaa ccggtgcggg acgacatggt ttctattacc ttttttccgt caagtgcagt
     2101 aactacagta gtgtaaagcg ctggggtttc agcggtccat ttacggggat tgtataccgg
     2161 aaaagcgact ttccaggatg cttcctcgcc tggctgaagg gcgcttacat ccgctgtacc
     2221 tgatttaatc agttttgtac catcatacaa ttctacggat acttttcttg ctggtgtttt
     2281 tgtagtgccg tagtttttta ttttaccgga tgcattcagg gtggcatgca catagttcgc
     2341 atcgagatca gtacttataa ggaagtcacg gatatgctcc tggggcgcgc tccacagcgt
     2401 tacattgcgg aaaatgccgc taaggcggaa catgtcctga tcttccatat aactgccggt
     2461 agtgaaacga tacacttcca cagcaatgat atttgcgccg ggtttcacaa attcagtgat
     2521 gtcaaactcc gcagcattgc ggctattgac gctatagcca attttatgac cattcaccca
     2581 taggaaaaaa cctgcgtcta cgccatcaaa ggttataaat atccgccggc catcccagtc
     2641 agcaggtaca tcaaaattac ggcgatagct gcctaccgga ttacgttctt tataggctgt
     2701 aaaattgact ggcggagtac tcattacccg gggaaaatcc ttctgaaaga tataattgaa
     2761 attactatag tatggtgtgc cataaccttc tacctgccag caggacggta ctttgatatc
     2821 tgcccatttt tccactgaaa aatctggttt gtaaaagtcc accggtcttt gttgcggcca
     2881 gggtacgtaa ttgaacttcc aggtgccgtt gagtgacttt gaaaaagaag aggcatagcg
     2941 atttgcgttg agtgcttctt tcagatctgc gtaaggcatc agggtggcat gggcaggttc
     3001 tttgttgata cccaggcatt ccggatcttc aatttctttg ggcacagtcg cggtgtcagt
     3061 tttgctgtgc catgggccgt gctgtagctg tatttgctgg aatgcgtaag acgacccggt
     3121 catgctgacg gcaatcaata gacttaataa tgaaaacttc atgattttat tttagtaaag
     3181 agattggttc cgcttcatta aaccagtaca gcgccgggga gccggcgctg tactggttta
     3241 tttataccat acaacgttta atatcccgca ttaggtgtaa gtcgtgtgtt ttgttccatt
     3301 gcactttgtg gaatgggcag ccagttcata tgttgtgaga atgtactgtt aaatatgggt
     3361 accttggtat aggttagtct accattagcc tccgtcgtaa ttttcatacc atattgcgga
     3421 tgagtaagta cggcttcccc ctttgtagtg atatcccagc ggcggatgtc gtaccagcgt
     3481 ttgtcttcaa acgcaagttc tattctgcgt tcgcggcgga tatttatacg catttcggtt
     3541 tgggtcattc ctgccggtaa cgcaggtaaa ccagcgcgtc ttctcacact attaatggca
     3601 ctatatacac tggcatccgg tccggtagct tcgttttgcg cttcagcata gttaagcagt
     3661 acttccgcat agcggtaaaa gatatagttg gaagtaccgg ggtaaattcc gagactggtc
     3721 tggccaagaa tagattcgtc aagggttttt ttgccattgt aaccagtatt actgatgtcg
     3781 ctggaggaac ccagatcgat ctggttattg ccgcctacac gtgataggaa tgtgtaaccc
     3841 tgccaggtag agccgtcata tacaatcgtc gcataaaatc gtggctcgcg gtttacatat
     3901 ggttgttgcg gatcgtaacc ggaagcaggg tctgtaatag gcaggccatt cgccatttca
     3961 tagtcgtcca ccagattttg ggtaggttca agatttcccc atgcctgttg tacgccatgt
     4021 acaatcactg gtccctgcat accttcccgg cggtgtcctt tgcttgggac tgcataccct
     4081 cttgcgaaga tcgtttcaat gttccagttg tttgctgcca gaaattgccc attgtagtca
     4141 gggaagaggt cataaacatt aagatctata accgctttat tagcagcggc agcttttgcc
     4201 catcgggccg gatcgttatt agtatttaca aggatgctgg cagcaaacag atctactgct
     4261 cctttaaggg taagggcagc acctttagta gcgcggcctg tagcagcagc ttttgtaggc
     4321 agatcagcag ccgcggcatc gcaatcagct tcgataaatg ccagcgtctc ctccatgctg
     4381 gcgcgaggaa tgaatatttt gtcgcccatc gtctgattat tcagtggctc ggatatcagc
     4441 ggaacacctc catagttttg atacaagaag gaataaaaca gtgcacgcag gaattttact
     4501 tccgctacgc gttgttgata ccattcatcg gagaaatgat cccggtattt tgcagcttgc
     4561 tgcaggaaca cattacatct gcggattcgg ctgtagttct cggaccattt aaacatagcg
     4621 ccaggtccat ccggcgcatt tgatggattc aacgcattag aacggatgag ggattgtcct
     4681 gtcatccacg tggcgcctac acaactgtta tccgtccatt ggtccagcag ctgagattca
     4741 ttattcatat caggcagctg gtcgtaaata tcatttacga aaagatcagc atttgcttca
     4801 gtggcgaagg tgctttcatc agtgagggat ccttttggat ctacattcag aaagccatct
     4861 tttttgcagg cgctcgtaat gaagatcagc agtgccagca cgaggacatg accgtatgaa
     4921 ttatatttat attgcatgat ttttacattt aaaaagtggc attaataccg aatgtgataa
     4981 cccgttgctg gaagtagttc atattgctgc tgttattctc cggatccagt atttccctga
     5041 tatggggagt ccaggtgaag agattttgcc cggaaacgta caggcggagc gagctgatac
     5101 tgtgacccag ggttttggat gagaatgtat atcccagctc agcactacga agccgcaggt
     5161 aggatgtatt acgcatccac caggatgatt gctgtgtatt gttggcggta ggtgcgcctg
     5221 taattcttgg atataatgcg tcagtattgg taggcgtcca gtgatcctcg tatgccagct
     5281 cagtggctga gccggatgac tggaagggcc atacaaagta ttggctcaca tacagggaac
     5341 tgtgaccgga accctggaac agcaggtcca cgtcaaatcc cttgtaagac agacgaggct
     5401 caaggccata aataatttca ggtgtactgg agtaaccgat gcgggtgatg tcgtttgcat
     5461 cgattctgcc atcgggttta ccgtctggac ctaataagtc ggcataacgt atatctcccg
     5521 cctttacatt accgaaactg ggtacaggaa tgccagcttt caggcttcca tcactattga
     5581 aatcattctc ctggaaatag ccgatggcct ggaggccaaa ctgcgtaccg ttagggcgtc
     5641 cggtttgacg gcgattgaca tttttgtagg tagcatcgtt ctcgtatact ttcagcagct
     5701 tgttacgtgc ataggtaaaa gtacccgtca catccagtcg taaaccgtta gagaatgttt
     5761 tgctactgcc caggctaagg tcaatccccc tgttctgcat gataccagcg ttaatcaaac
     5821 ctacaccaat accatattct gcgggtaagg agttacctat gcctacaagc atattggaac
     5881 gtttttcact aaaataatct gcctctatac tcaataagcc tttccacaga cttatatcaa
     5941 atcctatatc tgttttcctg gcacgttccc aggtgatatc aggattcccc tggagcgctt
     6001 ctttgatgcc ttgtgtagta ttgccgccaa ttacagcaga atttccattt acattgtaag
     6061 gactcaggta ctggtaagtc tggatgctgc cgccggagct gggatatgct ccggattcgc
     6121 cccaggaacc tcgtaactta agttgatcta tccatgtgat ctttttcatg aatgcttctt
     6181 cggaaatacg ccagccggca gagaatgcag ggaaaaagcc aaacctgtta ccaggtgcaa
     6241 acaggtagct gccatcgtaa cgaccagctg cctcgaaaag atacttattg tcataactat
     6301 aaccgatgcg gtagacgtat ccgagctggc gctgaccgtt ggatagtccg gagctggttg
     6361 catctgaagc ggccggacca ccgaagttca gctcatcaat gtccaggtta tagttgatac
     6421 gttgtgcgcg gaacgtctga tattttaccg agcgattttc cacgacggcc agcgcagtaa
     6481 tatcactttt accgaagtga ccaatataat taagcattcc ctggtaagta agcgccttat
     6541 tcatcgaaaa atcttcgtag aactgggcct tggaatttcc ctgaataccc ttcacatatt
     6601 cgtatggacg tttggtcgta tccacgttcc agaatgggat gggtgtccgg tattcgcgct
     6661 ggaaggaagt tttgttgttg aagatagggt ccggaccatt gtcgtagcta actactgctt
     6721 tgatactgag tcctttaaca ggtaattgct gatcaatgga caattgggtg atcagggaac
     6781 tgttttcact caggtggtag ccactatggt aaatttcacc aataagcgac tgaccaatat
     6841 agcctgtcca taaaccgttg ctgtaataaa ccggcgttgt aggcgcctga cgcatggcct
     6901 ggtcgagaat gctgcccgcg ccggtagcag gaaaatgctg gtcttcgacg taaccattag
     6961 ccatcagact aaccttcgtg gttttagtta cgttcgcagt cagactcaga ttagccatat
     7021 atttattcaa atacgtggta ctccacatac catcctggtg ctggtatccg acggacgcaa
     7081 aatattgata gtcgctgccg ccaccgctta aagacaggtt gtgataagta attggccggt
     7141 taggcttaat aatgtcgtca agcgggtgac cgtcagggtg gccatcggga tcagaatggt
     7201 ctctgaactt ctgaatatct tctgcgctgt aggcggcagg ctgtccatcg ttggcatttg
     7261 cctcgttacg cagcattgca tactggtaag agtttacaaa cttaggtacg cgcgtagggt
     7321 tctgaaatcc ataatatcca ttgtaagcca gtgtaggttt accagcctta cctgttttgg
     7381 tcgttaccag aattacacca ttggcccctg caacgccata aggcgccact gcagccgcat
     7441 cttttaatac ggtaaaagtt gctactgtat tagggtccag ccggctgaaa tcacggggta
     7501 caccatccac gataagcagt ggagcagtac ttccgatgga gccggcacca cggatctgga
     7561 tattagaggc atcaaagccc ggctctgcag aaccctgagt ggcaataagt cctgatactc
     7621 ttcccactaa gctgttgctc agattcacga ccggtttgtt agcaatctcg gcagtcttaa
     7681 tagtcgatat agctgcagtc agggaagttc gtttctgtgt accataacct actacaacca
     7741 catcgtttag tactttagct gattcctgca gctgaacatt tataactgct ctgccagcga
     7801 ccggtatctg ctggctttca tagcctaaaa aagaaaccac cagtgtagcc ttatctggtg
     7861 ctttcagcgt aaagtgtccg attgcgtctg tttgcgtgcc cgtgtttgtc ccttttatta
     7921 aaatactagc gcccggtatt ggttggccgg aggcgtccgt tatcagtccg gcgactgtta
     7981 tatctgcgcc aagtgacagt aatggtaaaa ataaaatcag caacaaggtt acgccggaaa
     8041 gccaccgctt attaaagctg tttccgtcgg ttggtgttcg tttcatgcgt ggatgttttg
     8101 taactggaat ttgataatga tggtataaga ttgtagaaac tcaaaattga gaaaagtagg
     8161 ggtaggcagt ttgcctttgt atgcatatga ccaacacttt tgtacttatt ttctatagga
     8221 gtggataata tgcgcttgcc agatcgtaca tttttctgtc actatcatac atctgatagg
     8281 taagaattcc aactgtagcg tgttttgcgg tttttaattt gtaaacttgc cagtgattgt
     8341 attaaaccaa aaacgctcag ttctgccgta cagatatttt ttgaaagtgt tgttgtcagg
     8401 gttgatcatg ttgatgacaa ccaggcagca tgtattggga caatcatacc cttaccattt
     8461 taacgccctc acggtagatg agggactttc tcatacagat gctactgaca ttgtgcagga
     8521 tcgatgggga tacatctggg tgtcgactct ttttggcatc aacaaatttg atggatacaa
     8581 cgtccggaga tattataata gtaatatacc cctgaataat gcttaccgca atcgcgtgat
     8641 ctgtatggca gtcgacagta ccggcttttt gtggttgggt acagaagccg gttttcagcg
     8701 ttttgatacc cgtacaagtc aatatatcga ttacccggtt agccagggat cgtcagcgaa
     8761 tgaccttacg aaaattgtga tctcctcatc acataccttt tacgccctcg ctagcaaaga
     8821 tcagctgcgc tgttatttgc tgaaaggcac aaccctacag gagaagaagc tgcatctgcc
     8881 tgaaggcgtc ggcatcagtg acatagctat ggacgtcggg ggacagctct atctggctac
     8941 tacaagtggc ttatgggtgc tgggcgaaaa tggtattgcg catatgataa aagtggcagg
     9001 ttgcgccgaa aatcacttca gcaaactctt tattgaccaa aaccgacacc tgttactcgc
     9061 tacgggtgaa agactttacc tggttcagac agtgggcgac tacccgagcg tggtcaaaac
     9121 tgctgccatt cgtggtgagg tgagcgatat ggtgcaggag gcgggaggca attactggat
     9181 taatagcagt cagcgtctga caagattgga taaaaacctg gtttttgttc aggagatcaa
     9241 taatgaaagt cccattaaat acgtcgatct aagcggactt caaagccttt tcattgacaa
     9301 atctcaatgt atatggaccg tcagttttgg caatggggta caatatgctg accttaatga
     9361 aaagaaattt tatacccttc agcacctgcc ggaaactccc tactctcttt cgggtagcta
     9421 tgtgcgggcc attctggacg agaacgggaa ggatctctgg gtaggcacaa gcgatcatgg
     9481 gctgaaccac tatgatcttc agaagcagca ggtggtacag gtatataaca attataatag
     9541 tacggtgcgt ctgcctgaga atacaatcac ggcactggca actgacaatg agcataattt
     9601 gtggataggg gggcagagcg gtattactgt catgcgcccc aatcgccagg aactttggcg
     9661 accaccgggg gcagagaatt ttcctgcaca tgttatagat gtattggcca aagattgctt
     9721 tggtaatatc tggtttggtg accatacaca taaatttggc gtaatcttta aagacgccgt
     9781 agggaaatac catgtaaaag aatacgggga aagctttttt atacatgcag attccgtgaa
     9841 gccccagttg atgatttcca gtacacatgg cctgaagcga cttataatag ataaggaagg
     9901 taatattgta aaaagctgga gctacgaagc tactggtaaa cctaattcac ttagttccaa
     9961 ctatacttat ccgattgcaa aacagaacga cagtatatat tggataggaa ctatcggcgg
    10021 cggactgaac cgcataatcc tccgtgctga tgatacttac gccattaccc agtttactaa
    10081 aggtgttttt aaagatgtag aaggactgga agtagatgat aaaggtttta tatggctggc
    10141 aggcaatggt ctgcaacgtt tagatccgcg tactggtgcg gtaattcgct atgataaaaa
    10201 agacggacta cagggaaaca gcttcaaggt taattcttcc tgccgcggag ccaatggaat
    10261 gttattcttc ggtggtataa acgggttgaa ttatttccag ccattggaga tcacagccaa
    10321 ccctatagct gccgtcccac aaattagccg cctttctgtg aacaacgaag ctgcggactc
    10381 tgcccgttat atcacaaacg tcgccgcagt acgccttaat tatctgcaga ataatttcgt
    10441 aattttcttt agtgccatgc actatgcgaa ccctttgaaa tgtcgcttcc ggtatatgtt
    10501 gaaaggctac gatcacgtct ggcaatatac agatggtaac catgccagcg ccgcttatag
    10561 taaccttgac tttactgagt acaaattcat agtagaagcc tctaataatg atggcgtctg
    10621 gaatagtcag caggccagcg taactattat tatgatacca ccatggtgga agagcttccc
    10681 ggcgaagcta ttttacattt tacttattat ggcggtcctg gtaggtattt atatttatca
    10741 ggcccggtgg taccggctta agaatgagct tctactgcgt gccgtagcag aacgacaaag
    10801 agaagacatt catcagcagc gtgagcaaat gtaccagcaa caattacagt tatttacaaa
    10861 tatctcccat gaattccgta cacccttaac gcttatccgt ggtccacttg aatacctgat
    10921 ctcacatgat ggccagtcaa cacatttaca tgcttaccag ctcatgctac gcaatgtgaa
    10981 acggttgatc aatcttgtaa gtgaactgat gaattttaaa aaggtagcag atggcgctat
    11041 ccgcctacag gtacagccta tgtcaataga tgaattttgc cagagcctat atacagagtt
    11101 tggagctcta gcagagagta aaaatatagc ctttaatatc acaggcgata taggccaacg
    11161 ggatattata agctattttg acgcacaggt acttgagaag attttgctga atctgttaaa
    11221 taacgctttt aaatatacaa gcaacggtgg taaggtgacc atgcagtatt ttctggatga
    11281 ggataagttt aaaccatctt ttgatacggg cttccgattg ccaaatgagt ttaaggccag
    11341 caaatatatt tatttcctgg tctccgatag tggtattgga atttcagaag catctattca
    11401 aagcatattt gatcgttatt acagggtgag caaccatcac ctgggatctg gtgttggcct
    11461 ggctttagta aagagtctta ctcaattaca caaaggagag atagccgtat ttagtgagcg
    11521 gaataagggc acggaatttc tggtggcctt accctggggt aaagaaaact acagcgctgg
    11581 tgagatcata gagcccggaa gtatgtcggg gtcgcagttg gagcagctgg atagtccaac
    11641 gccattattg tcaaagcctg tgcctacggc gccaatgagt acccgaaaag ccaggcatat
    11701 cctgttagtg gaagataacc aggagctacg tacctttttg cgcgaatcgc tcgaaccata
    11761 ttaccatata catgaagccg cggatggaaa tagtgcaatg actatagcca cagaacttaa
    11821 tcctgacctg ataataagtg atgtaatgat gccgggcggg aatggtatcg acttgtgtaa
    11881 acacattaaa caaaccttcg agaccagcca tattcctttc gtaattttat ctgccaggga
    11941 tgggttggaa accaaaatag aaggtctgaa gtcaggggct gattactatt ttgcaaagcc
    12001 actgaatatg tccctccttc tgttgactat taataatatt tttgagcaga attcgaaact
    12061 gaaacagcgc tatacgaaag atcatctcat agaggccacg gaattagtgc attcagaaaa
    12121 agacaaggat ttcatgaata cattgctcca gattattgag gaaaatatac aaaaccctga
    12181 gctggaagtg gaattcctgt gtatgcgtat gaacataagt cgtacaaagc tttaccagaa
    12241 aatcaaaggc atttcaggac agtccgttgg cgaatttatt aagacaattc gtttaaaaca
    12301 ggctatttat attatgacac acgaggatat aacgctgtca gaagtcgccg acagaatagg
    12361 gctacagagc agttcgtact tttcacggat gtttaagaaa gaatatggaa gcactccttc
    12421 cgaatttgta aaaggtctga gaaacgcatc aaaataggga atcagcaata gacaatctcc
    12481 actcactgtt tcagagaata gttttatact agtattggaa gaatgttggc tttataagaa
    12541 acctctttaa gtgagacata agaccagttt gatttttgta cttttatgtc tatgaaaata
    12601 gacagagagg agtatcctga tccggctgcg gttccggaaa ataaaggaaa gcatatcata
    12661 cacaccggag gagctcattc ttcttatctg cagcttccgg tcaaatcaat ataatactgt
    12721 tggtgcagat ctcctaatac tggtttctct attaagagat agagatctgc attatcataa
    12781 tcagttagtc catctaccgt tatttctacc attttccccc tgcccaggag gcctttcgga
    12841 cctgaatttt tcattttctt ccacatttac acaacaaagg gcaacaaaat actttacgtc
    12901 aaaaaatatg gacgaatggg caagcccctg aaggttgaat gtttgttatt tgcatcatcc
    12961 ccatctgaaa aaaccactat ggaaccctaa agatgcaggg atacctatat ataatcgaaa
    13021 ttttaaacct ctaaagaaaa ttccatttat gaaaacactg aaaagcaacc ttttcggagt
    13081 tgcagtcaca tttgcaagtg tgcttctgct actcagttcc tgtaagaaag cagagcaatc
    13141 actgcccgta gacaagctgg atctgacaac aaagtcagcg gccaacgcat tattgctggt
    13201 ggaagctaac cctaatgccg atgcggcgtt caattcattc aattcgagtt ttctggtttc
    13261 ttccggaaca actcaatatt acaaagaggc cctgaatgtt tcgggcaagg attatttctg
    13321 gcgccaggcg ctggatattc agatggtcga agacgtttac ctgcgcacgc agagtagtgc
    13381 tcatagaact ctgataacca atatgctgaa tacctttcta cagcagaacc agggcagcgg
    13441 cggattatat gactggaact ggaatgattt caatgatgac cttcagtggg caggtattgc
    13501 ctttgcacgg ggttaccaga taaccggcaa cactacctat cttaatcagg cgaaatatgc
    13561 ctttgatcgt agttataacc gcggttggac aactgaactg ggcggaggcg tctggtggga
    13621 tgttaaccac gaaagtaaat ccggactgag taacaaccct gaaatgattc tgggctgtta
    13681 tatctatgag gccacgaagg atatcggcta tctgaacaaa gtgatagcga tatacaattg
    13741 ggtaaaggct acactctata attcagctac gggtgctgta tatgagaata tccgtcctga
    13801 tggaacagtc agcgccgatg ccaatgttta taatattggt gcttttgtca gtgcagccaa
    13861 tcaccttcac cgcctgaccg gaaatgctgt gtattacgat gatgccaaac ggtcagtgga
    13921 ttatgtaagg aacaataaga cggtcaacgg aattatgaca aatggacaac gtcagggtac
    13981 ctggcagtcc gaatttatca ggggactggg cgaatttgtt cgggataaca atctttggag
    14041 tacctattac acctggatga aacagaatgc tgatgccgcc tggaatatac gccgcacaga
    14101 cagaaacctg atgtggaaca actggacaac gaccacacca tccgataacg ttacgacagc
    14161 ggtagaatgt attggaggcg taattatgca gcagatcacg ccgacaacgc agccaactgg
    14221 cattaccaat aattcagttt acagactgat tccgaagatt aacgagaaca gtgccctgga
    14281 tatcgctggt tccgccagtg gttcacttgc cggaatatgg gattggaata acggattaaa
    14341 tcagaaattc cggatggtat ccctgggata tggttatttc agacttgtac cacagcataa
    14401 cacagggacg tcgctggatg tgaccggagg aagcgccgag aacaacaccc cgatagagat
    14461 atggacaagt aataacaatt catcacaggc atttaaagtt gtttacgact atcacggcta
    14521 ttataaattg aaaccgaaat gtgcaccatc gagctgcgtt aacgtggcag gagctaatcc
    14581 cgctaatgga acaaagtgtg tcttgtggcc ggaatccaat gtggatcagg aacggtttgc
    14641 gctggcggtg caataa
//
