LOCUS       NC_013132              13159 bp    DNA     linear   CON 26-AUG-2019
DEFINITION  Chitinophaga pinensis DSM 2588, complete genome.
ACCESSION   NC_013132
VERSION     NC_013132.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN00001914
            Assembly: GCF_000024005.1
KEYWORDS    RefSeq.
SOURCE      Chitinophaga pinensis DSM 2588
  ORGANISM  Chitinophaga pinensis DSM 2588
            Bacteria; Bacteroidetes; Chitinophagia; Chitinophagales;
            Chitinophagaceae; Chitinophaga.
REFERENCE   1  (bases 1 to 13159)
  AUTHORS   Glavina Del Rio,T., Abt,B., Spring,S., Lapidus,A., Nolan,M.,
            Tice,H., Copeland,A., Cheng,J.F., Chen,F., Bruce,D., Goodwin,L.,
            Pitluck,S., Ivanova,N., Mavromatis,K., Mikhailova,N., Pati,A.,
            Chen,A., Palaniappan,K., Land,M., Hauser,L., Chang,Y.J.,
            Jeffries,C.D., Chain,P., Saunders,E., Detter,J.C., Brettin,T.,
            Rohde,M., Goker,M., Bristow,J., Eisen,J.A., Markowitz,V.,
            Hugenholtz,P., Kyrpides,N.C., Klenk,H.P. and Lucas,S.
  TITLE     Complete genome sequence of Chitinophaga pinensis type strain (UQM
            2034)
  JOURNAL   Stand Genomic Sci 2 (1), 87-95 (2010)
   PUBMED   21304681
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13159)
  AUTHORS   Lucas,S., Copeland,A., Lapidus,A., Glavina del Rio,T., Dalin,E.,
            Tice,H., Bruce,D., Goodwin,L., Pitluck,S., Kyrpides,N.,
            Mavromatis,K., Ivanova,N., Mikhailova,N., Sims,D., Meinche,L.,
            Brettin,T., Detter,J.C., Han,C., Larimer,F., Land,M., Hauser,L.,
            Markowitz,V., Cheng,J.-F., Hugenholtz,P., Woyke,T., Wu,D.,
            Spring,S., Klenk,H.-P. and Eisen,J.A.
  CONSRTM   US DOE Joint Genome Institute (JGI-PGF)
  TITLE     The complete genome of Chitinophaga pinensis DSM 2588
  JOURNAL   Unpublished
REFERENCE   3  (bases 1 to 13159)
  AUTHORS   Lucas,S., Copeland,A., Lapidus,A., Glavina del Rio,T., Dalin,E.,
            Tice,H., Bruce,D., Goodwin,L., Pitluck,S., Kyrpides,N.,
            Mavromatis,K., Ivanova,N., Mikhailova,N., Sims,D., Meinche,L.,
            Brettin,T., Detter,J.C., Han,C., Larimer,F., Land,M., Hauser,L.,
            Markowitz,V., Cheng,J.-F., Hugenholtz,P., Woyke,T., Wu,D.,
            Spring,S., Klenk,H.-P. and Eisen,J.A.
  CONSRTM   US DOE Joint Genome Institute (JGI-PGF)
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2009) US DOE Joint Genome Institute, 2800 Mitchell
            Drive, Walnut Creek, CA 94598-1698, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 08/26/2019 00:28:39
            Annotation Pipeline               :: NCBI Prokaryotic Genome
            Annotation Method                 :: Best-placed reference protein
            Annotation Software revision      :: 4.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
            Genes (total)                     :: 7,171
            CDSs (total)                      :: 7,077
            Genes (coding)                    :: 7,009
            CDSs (with protein)               :: 7,009
            Genes (RNA)                       :: 94
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 19 of 68
            Pseudo Genes (incomplete)         :: 47 of 68
            Pseudo Genes (internal stop)      :: 11 of 68
            Pseudo Genes (multiple problems)  :: 8 of 68
            ##Genome-Annotation-Data-END##
            ##Metadata-START##
            Organism Display Name :: Chitinophaga pinensis UQM 2034, DSM 2588
            Culture Collection ID :: DSM 2588, ATCC 43595, LMG 13176, UQM 2034
            GOLD Stamp ID                     :: Gi02244
            Funding Program                   :: DOE-GEBA 2007
            Gene Calling Method               :: Prodigal
            Isolation Site                    :: Pine litter in Australia
            Isolation Country                 :: Australia
            Oxygen Requirement                :: Aerobe
            Cell Shape                        :: Rod-shaped
            Motility                          :: Motile
            Sporulation                       :: Nonsporulating
            Temperature Range                 :: Mesophile
            Temperature Optimum               :: 23 - 24C
            pH                                :: 7
            Gram Staining                     :: gram-
            Biotic Relationship               :: Free living
            Diseases                          :: None
            Phenotypes :: Biomass degrader, Chitin degradation
            Energy Source                     :: Chemoorganotroph
            ##Metadata-END##
            REFSEQ INFORMATION: The reference sequence was derived from
            CP001699.
            URL -- http://www.jgi.doe.gov
            JGI Project ID: 4082984
            Source DNA and organism available from Hans-Peter Klenk at the
            German Collection of Microorganisms and Cell Cultures (DSMZ)
            (hans-peter.klenk@dsmz.de)
            Contacts: Jonathan A. Eisen (jaeisen@ucdavis.edu)
            David Bruce (microbe@cuba.jgi-psf.org)
            Whole genome sequencing and draft assembly at JGI-PGF
            Finishing done by JGI-LANL
            Annotation by JGI-ORNL and JGI-PGF
            The JGI and collaborators endorse the principles for the
            distribution and use of large scale sequencing data adopted by the
            larger genome sequencing community and urge users of this data to
            follow them. It is our intention to publish the work of this
            project in a timely fashion and we welcome collaborative
            interaction on the project and analysis.
            (http://www.genome.gov/page.cfm?pageID=10506376).
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Annotation Pipeline (PGAP)
            set; GeneMarkS-2+
            repeat_region
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..13159
                     /organism="Chitinophaga pinensis DSM 2588"
                     /mol_type="genomic DNA"
                     /strain="DSM 2588"
                     /type_material="type strain of Chitinophaga pinensis"
                     /db_xref="taxon:485918"
                     /note="type strain of Chitinophaga pinensis"
     gene            complement(1..870)
                     /locus_tag="CPIN_RS31475"
                     /old_locus_tag="Cpin_6364"
     CDS             complement(1..870)
                     /locus_tag="CPIN_RS31475"
                     /old_locus_tag="Cpin_6364"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_012793932.1"
                     /translation="MKWIKDVNIFILSTLGVFLAAGCITQASSPSPTDSIMTDSAAVAI
                     DSITATADMIAEPDSLQGEMYVIDGLIGLIAESSLQLSNASMPPVAGRDTLNATLYHEN
                     GHPVEMSYTLFEDGGAAAGIGNMYFFADYPIVSELAYGDTHIYNVLRKDSTFFSFSRNG
                     RNYFKLITLPEGAEDLRIAHLIKDAADMLQLYPRNKIRFNVPSVPLRGDLKLLAVADVP
                     MYEWPDSTLPSILVIPENAVLGFMGANMQEVVTDGKKWIWYEVTCGGVHGWINGHPAFV
                     QERNDEVY"
     gene            complement(908..2647)
                     /locus_tag="CPIN_RS31480"
                     /old_locus_tag="Cpin_6365"
     CDS             complement(908..2647)
                     /locus_tag="CPIN_RS31480"
                     /old_locus_tag="Cpin_6365"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="GH51"
                     /protein_id="WP_012793933.1"
                     /translation="MKRILVLFFLCSEILLCTACNKNSGEPYEGEETDTSGTTVIVPED
                     PALASSIGFFMSSWAPKTFKAGTFTEAALPGSAPYLVTVDASTITTKISPALFGNNSNP
                     YMSQMVNQPKLIGHLTNLRTGIIRFPGGNISSVYFWNGQVGIPPADAPVQLTDADGNKT
                     DPGYWYGNNTADWTLSVNNYYSMLQQTGNEGMITVNYGYARYSTAANPVAAAAHLAADW
                     VRYDNGRTRYWEIGNESNGTWQAGYRIDVTQNKDGQPQVISGELYGRHYKVFADSMRKA
                     AAETGKTIYIGAQLLEHEPAIWATDTDKKWNAGVLQQVGATADFYIVHSYFTPYNTNSN
                     PQEILASAATVTKAIYDHVNGSFTANSVAAKPVALTEWNIFAVGSQQMVSQVAGMHAVM
                     VWGELIRNKFGMSSRWDLANAWENGNDHGLFSQGESLSGETKWTPRPAFYYQYFFQKFL
                     GDRGINATVTDSNSSISAYASTFSSGEVGLTLVNRANITRNVTVNFKNFLPGARFYWYV
                     LTGGEGVTGFSRKVFVNGAGPTGVSGGPDNYAALIPYGGSATGGVKVSLPPMSVVNMVI
                     EKK"
     gene            complement(2723..3982)
                     /locus_tag="CPIN_RS31485"
                     /old_locus_tag="Cpin_6366"
     CDS             complement(2723..3982)
                     /locus_tag="CPIN_RS31485"
                     /old_locus_tag="Cpin_6366"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_012793934.1"
                     /translation="MTRNIFTFIRYMNRLPLYLLILFTVFCAACSKDDGSSGAPPVVTG
                     VSLLDASKTDSTFAGTLPGTLILITGQNLDGIVKIAFNGQAAYFNPTYNTRTHLIVTIP
                     DNAPTEATDPDVPNTIHIITSHGETSYSFTLEIPPPSIVAISNENALAGDSLIIYGSSL
                     WLIDKIVFPGGREVTDFIADDAGTRVGMIMPALGDDTGRLVIQAKYGTAVSDGPLNDHE
                     SGNVISNLTADGETGEKAVFNWAYWGANRTTDATLFPGTRGGYLQNIFGGVGVNDGAWW
                     NGNRSGNFNDVPMFTAAIMTEQASSYALKFEISTKEPWTAGVNVLRFGDNYAYRYMPWS
                     GAAGAKFETKGAWQTITVPLSAFKTVADGKEGTGAGAQTMGDLLKAGGVVAFGYRFITE
                     DAPVDVYNAAYDNFRIVKIR"
     gene            complement(3999..5642)
                     /locus_tag="CPIN_RS31490"
                     /old_locus_tag="Cpin_6367"
     CDS             complement(3999..5642)
                     /locus_tag="CPIN_RS31490"
                     /old_locus_tag="Cpin_6367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009279815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RagB/SusD family nutrient uptake outer membrane
                     protein"
                     /protein_id="WP_012793935.1"
                     /translation="MKKTNYHIYLIALACTLFAAGCSKDFLNRPPEDAIVDVNFYQTTD
                     QILAGTAPLYNIVWFAYNDKASHGIGDGRAGILMSGSYQVDNIRMQTTDVTPEVYSSWT
                     SFFNVVAQANQIISNLVTYTAPTVPENVKQAGIAEGRFMRGVAYSYLVQNWGAVPIIAD
                     NKVLLTDTSISRNTIASVWEFIIRDIRFAAENLPAAPMQKGRLTKWAAEGMLAKMYLTR
                     AGISGSKNQTDLDSAAWYANDVIMNSGAALMDNYEDLFLVKNNNNSESLFALQWKYDGD
                     WGTQNSVQAFLAYGSEITGFGDGWGGDLGASLDQLKLYRIDDKRRKGTFMFPGDHYSYI
                     HQSVDDPNNPGKKIIQELQVPWNYVGTERYNARAWVKKYVVGRPEDNDGKVTQQHTEIN
                     TYMLRLADVYLIYAEALLGKSASTTNAQALLYFNKVRKRAGVPEKTVLTWDDIYIERRL
                     ELAMEGQAWYDLVRLYYYDPAKAISLINAQDRGTYRVAANAATNATSWTITSDVPAFYN
                     VTQSNFLLPLPAAELTAAPNLRKPPVPYQF"
     gene            complement(5663..8860)
                     /locus_tag="CPIN_RS31495"
                     /old_locus_tag="Cpin_6368"
     CDS             complement(5663..8860)
                     /locus_tag="CPIN_RS31495"
                     /old_locus_tag="Cpin_6368"
                     /inference="COORDINATES: protein motif:HMM:TIGR04056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gnl|TC-DB|Q45780|1.B.14.6.1"
                     /protein_id="WP_012793936.1"
                     /translation="MKRASITGKSYLTVWVMIFFWAVTMPAQAQTQSDPGRKISGSVTA
                     GETGTPVPGASITIKGTKRMTTTDGAGNFSIPAAPGEVINIASMGFITREFKVGNSATV
                     NVVMQEDYRKLNDVVVVGYGKMKKTDQSSAQVSITSTEVNRTINTTIDQAIQGRAAGVY
                     VTQNSGQPGGGISVNIRGVNTLSGTNEPLYVIDGVQMQPATVSYGATSSVNPLAGINPS
                     DIESLEILQGPSATAVYGSRATNGVILVTTKRGKSGQMKLSYNYLYSLQDKPEAVNTMT
                     LQQFAIMNNEIAQLLNRTPTPEFQNPGVLGKGTNWQDALFRTASLQKHQVNISGGASNT
                     TYYMSGEYFDQEGVAIGSDFNRYSFRLNLDNQAFKWLKLSTSLNFYQTKEKLASTSEDV
                     IRNAINLAPNIPVKNADGSWGGATENEYGSNAKYAPLNPVAIASLVSNDYKRTGGLGGA
                     TAEISIIKGLTFRTSFNGNFEYTDGSKFIPTYQLGYNVNEKASLAVSNGKNFYWNLNEL
                     LQYSRDIGKHSFSVMVSHEAQAWNYQGFSAQRVGFASNSIPSLNLGNALGQTTGSYKGS
                     GALESYLGRVNYTYDNKYIVQLAGRADGSSNFGADDRWGYFPSVSVAWRLTGEEFMKSL
                     PFINELKIRAEYGTTGNNGSGGAQFSSLTSVTTPWGAGFRTGQYGNSGLKWESTETKNI
                     GFNMSVLKDRIQLEGDFYIKKTDNLLMPNPLPAYMGTQGEGAINAPIVNIGAMQNKGFG
                     ITLNTVNIDNKQGFSWRTNFNISSFKTKITKFYSDAAFLSRSAWFMNNFTSRSVIGDAP
                     WQFYGYVAEGLFQSVDEINSSAIPAQSDGTRLPVAKDGGVWVGDIKYKDLNGDNIIDSR
                     DQTFIGNPWPKLTFGLTNTFSWKGFDLSVLMTAAQGNDIFNYLRFENTNPNNINLGRNL
                     LQESFNYARVGDVGGKTILENPGANVPRIVGTDVNGNGNRFTNLYVEDGSYIRIKNVQL
                     GYNIPHALLRQQSVVKNIRLIAGVQNLATFTKYKGYDPEVGSYLGKEVQLSSQLIGVDA
                     GRYPLTRLYSASVAVDF"
     gene            complement(9059..13159)
                     /locus_tag="CPIN_RS31500"
                     /old_locus_tag="Cpin_6369"
     CDS             complement(9059..13159)
                     /locus_tag="CPIN_RS31500"
                     /old_locus_tag="Cpin_6369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014218988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DBD-Pfam|HTH_AraC,DBD-Pfam|HTH_AraC,DBD-SUPERFAMI
                     LY|0036286,DBD-SUPERFAMILY|0035607,DBD-SUPERFAMILY|0035607"
                     /protein_id="WP_012793937.1"
                     /translation="MLMKNLLLPLLLLVSYAYAQPSYQFSSLDVNNGLSNNQVNSIYKD
                     ARGFMWFGTMSGLNRYDGYAFKTFRHSAEPGVINDDYITGIYPAPNNQLFIRTRNGDNF
                     YNPVTEQFSDATTWLKKKGLSEYGITSVAQTGRNWWIAYNDARLYKTDSTGRTTKILLP
                     DRANAAIADLQGEGDKLLVILYLNGDVEKLDIASNKIIYRNSNIRKYIGKPPLALRIFI
                     DAAKDMWVYMPGSDFGVAYLNRTDGKVKMLSSKTGALNNDIVNSIVEDDKHFIWIGTDH
                     GGINLIDKNNNFKSRFLVNKEGDLKTIAENAVYALYKDNFGIIWCGTYKRGLSYFTENM
                     VKFPLYKHSHADNNSLSYNDVNCFAEDEKGNIWIGTNGGGLIYFDRVNQTFKRFQHDPS
                     NDNSISKDVIVSLYVNNYNDLWIGYYFGGMDFYSNGRFNHYRHEEDDPNSLANKSVWKI
                     YRDQRNNFWVGTLGGGLDRFDPGNGIFYHNNVNMPASVHSNYISGFAEDNRGNLWIATA
                     YGIDVLDNSKGVFVHYLSSTHQLSNDNVSSLLYDKRGHMWAGTRAGLNVFDEKVQQFRS
                     FTVKDGLPDNNIITMLEDNEGYLWASTSNGLSRIAVKDGPEGLSISCRNYDDKDGLQSK
                     AFNVNAAFKLSTGELIFGGADGFNLFDPSSLPRNNTRPDVVFTGLRLFDRNIEVNAKVH
                     DRVLLPEALSVTKEIVLKHNENDFSLEFAALNFINTEKNKYAYRLDQFNDNWLIADGST
                     RRITYTNINPGTYTLQVKAANEDGFWNEEGISLKIIVKPPFWKTPLAYIIYVLLTVAIL
                     LLLRRSVIRRAHKRFTLEQERQEARRMHEMDMMKIRLFTNLSHEFRTPVSLILSPLEEI
                     MQQSGEQKEKGKFQLIYRNAKRLLILVNQLMDFRKMEMQELRLNPTWGDIAVFIREVTF
                     SFADLAERKQILFSYKSNAPHVYTYFDNDKIERILFNLLSNAFKFTPSGGAVHVEVNSN
                     KDEQEKTWLEMKVRDTGIGIPEERHEKVFEQFFQSDMPGGLMNRGSGIGLAITREFVKL
                     NNGTITVESEVNKGSCFTVRLPLETCEQPEVADEPQEGVKDQLLTEDPLFAEELPEELS
                     EEELATDTQRQTVLLIEDNEDFRFYLKENLKDCYHIIEGADGIAGWQKTLSGHPDLVMS
                     DVNMSGMNGIDLCRKIKNDPRTKHIPVILVTAAAGEQEQLRGLEAGAADYLVKPFNFEI
                     MLSRVRNLLARPLPAKHQVSLPELQNAENEASPNEKFLRRVLEIVEQNLSNAGFSVEEL
                     SRELYMNRVSLYRRIFNLTGQTPVEFIRMIRIKRAAQLLSKTEMNVTEVAYEVGFNNPK
                     YFAKYFKMAYNMLPSAYATAARK"
ORIGIN
        1 ctaataaact tcatcattcc gctcctgcac aaatgcagga tgtccattga tccatccatg
       61 tacgccgcca cacgtcacct cataccagat ccatttctta ccatctgtta ccacctcctg
      121 catgttcgcg cccataaatc ccagcaccgc gttttcaggg atcaccagta tcgatggtaa
      181 agtagaatcc ggccattcat acatcggtac atccgctacc gccagtagtt tcagatctcc
      241 tcttaaaggc acggaaggta cattaaaccg gatcttattc cgtggataca attgtaacat
      301 atcagccgca tccttgatca gatgtgcgat ccgcaggtcc tccgcccctt ccggcaatgt
      361 gatcagctta aaataattac gtccgtttct gctgaaggaa aagaaggtac tatcttttct
      421 cagcacatta tagatatgcg tatcaccata tgccagttca ctgacgatcg gataatcggc
      481 aaagaaatac atattaccta tccccgcagc agccccgcca tcttcaaaaa gcgtatagct
      541 catttcaacc ggatgcccgt tttcatgata aagcgttgca ttcagcgtat ccctgccagc
      601 caccggcggc atactggcat ttgacagctg taaagacgat tcagcaatca accctatcaa
      661 accatcaatt acatacattt ccccctgcaa tgaatcaggc tccgctatca tatctgctgt
      721 ggcagtaata ctgtcaatgg ccaccgcggc actgtcagtc atgatgctgt cagtcggaga
      781 gggactactt gcctgggtga tacaaccggc agctaaaaat acacctaaag tactcaggat
      841 aaatatgttg acatctttta tccatttcat gacatagagt tatattattt atttctcaaa
      901 tataactcta tttcttttct atcaccatat tcaccacact cattggtggt aaagatacct
      961 tcacccctcc tgtcgcactg cctccgtaag ggatcagcgc cgcataatta tccggccctc
     1021 cggatacgcc cgtcggtcct gcaccattta caaatacctt ccgtgaaaaa ccagtcactc
     1081 cctcccctcc tgtcaacaca taccagtaga aacgggcccc gggaagaaaa ttcttaaaat
     1141 tcaccgtcac attacgtgta atatttgccc tgttcaccaa tgtcaatccc acctctccgg
     1201 aactgaatgt tgacgcatag gcactgatac tcgaattact atctgttaca gttgcattaa
     1261 ttcctctgtc tcccaggaat ttctgaaaga aatactggta ataaaaagcg ggtctgggcg
     1321 tccattttgt ctcacctgaa agcgattctc cctgactgaa taatccatgg tcattaccgt
     1381 tctcccatgc atttgccagg tcccagcgac tggacatacc aaatttatta cggatcagct
     1441 ctccccatac catcaccgcg tgcatacctg ccacctgcga taccatctgc tgagaaccta
     1501 cagcaaatat gttccactcc gtcagcgcaa caggttttgc cgccacgcta ttcgcagtaa
     1561 aagaaccatt gacatgatca taaatagctt tcgtgacagt agcggcagaa gccagtattt
     1621 cctgcggatt tgaattcgta ttataagggg tgaaataact atgaacgata taaaaatcag
     1681 ctgtagcgcc tacctgttgt aatacgccgg cattccattt tttatcggta tcggtcgccc
     1741 agatggccgg ctcatgctcc agcaactgag cgccgatgta aatggtcttt cctgtttctg
     1801 ctgctgcctt acgcatagag tcagcaaata ccttgtaatg acggccatat aactctccgc
     1861 tgatcacctg tggctgccca tccttattct gcgttacatc tattctgtaa ccggcctgcc
     1921 aggtgccatt actttcatta ccgatctccc agtaacgggt acgtccgttg tcatacctta
     1981 cccagtctgc cgccaggtgt gccgcagcag caaccggatt cgcagcagta ctatatctgg
     2041 cgtagccata attcaccgta atcattccct cattccccgt ttgctgtaac atactgtaat
     2101 agttgttgac agacaatgtc cagtcagccg tattgttacc ataccaatac ccgggatctg
     2161 tcttgtttcc atctgcatct gtcagctgta caggtgcatc cgcaggcggt atacctacct
     2221 gtccgttcca gaaatacaca ctgctgatat tccctccggg aaagcggata atacccgtac
     2281 gcagattagt cagatgtcct atcagtttcg gctgattcac catctggctc atatagggat
     2341 tgctgttatt gccaaacagc gcaggagaaa tcttcgtagt gatcgtcgat gcatccaccg
     2401 taacgagata cggggcagat ccaggcaatg cggcttccgt gaaagtgcct gccttaaaag
     2461 tctttggcgc ccatgacgac ataaagaagc ctatactgga cgccagtgca ggatcttcag
     2521 gtactatcac cgtagtaccg gaggtgtccg tctcttctcc ctcgtatggt tcaccactgt
     2581 ttttgttgca ggccgtacac aacaatattt ccgaacataa aaaaaacagg accaatatgc
     2641 gcttcattct taaatacgta ttaataagtt tgtgctataa caggtccgca gtaaaactac
     2701 tgcagacctg tcattgatat tactatctga tcttcactat cctgaaattg tcatatgcag
     2761 cattgtagac gtctacaggt gcatcttctg taatgaagcg ataaccaaaa gctaccacac
     2821 cacctgcttt caacaggtcg cccattgtct gtgcacccgc accggtacct tctttaccat
     2881 ctgccactgt tttgaaagca gacaaaggca ccgttatcgt ctgccacgcg cctttcgttt
     2941 caaactttgc accggcagcg cctgaccatg gcatatagcg atacgcataa ttatctccga
     3001 aacgcaacac atttacacca gccgtccagg gctcttttgt gctgatctca aacttcaatg
     3061 cataactgga agcctgctcc gtcatgatcg cagccgtgaa catcggtaca tcattgaagt
     3121 tacccgaacg gttaccattc caccatgcgc catcattcac acctacgcca ccgaaaatgt
     3181 tctgtaaata gcctcctctt gtaccgggga acaaagtggc atctgtcgtt ctgttagcgc
     3241 cccagtaagc ccagttaaaa acagccttct cacctgtctc cccgtcagcc gtcagattac
     3301 tgatcacatt tccgctctca tgatcattca gcggaccatc cgagacagcc gtaccatatt
     3361 tcgcctgtat gaccagtctc ccggtatcat cccccagcgc cggcatgatc atccctaccc
     3421 tggttcctgc atcgtctgcg ataaaatcgg ttacttctct acctccagga aacacgattt
     3481 tgtcgatcag ccataagctg gaaccataaa tgataaggga atctcctgcc agcgcatttt
     3541 cattcgatat ggcgacaatc gatggaggag gaatttccag ggtgaatgaa taacttgttt
     3601 caccatgact ggtgatgata tggatggtat tgggtacatc cggatctgta gcctctgtag
     3661 gcgcattatc cgggatcgtg actatcaggt gcgtacgggt attgtaagtg ggattaaagt
     3721 acgccgcttg cccgttaaaa gctattttaa cgataccatc aaggttttgt cctgtgatca
     3781 ggattaaagt accaggcaga gtcccggcga aagtactgtc tgtcttgctg gcatccagca
     3841 gactgacacc tgtcacgaca ggcggcgcac cactgctgcc gtcgtccttg gaacaggcag
     3901 cgcaaaacac agtgaacagg atcaataaat acaacggcaa cctgttcata taacggataa
     3961 acgtgaatat attacgggtc atgatcagtc agttttaatt agaattgata aggtaccggg
     4021 ggcttcctta aattaggtgc agcagtcagt tcagccgccg gcaacggcaa caggaaattg
     4081 ctctgagtca cattgtagaa tgccggcaca tcagaagtga tcgtccagga agtcgcattc
     4141 gtagcagcat tggcagcaac acgataagta cccctgtcct gcgcattaat cagcgaaatc
     4201 gctttcgcag gatcatagta atacaacctc acgagatcat accaggcctg tccttccata
     4261 gctaactcca gtcttctttc aatataaata tcatcccagg taagcaccgt cttttcaggt
     4321 acacccgctc tttttctcac cttattgaag tacagcaatg cctgtgcatt agtagtagaa
     4381 gcagacttcc ccagcaatgc ttccgcatag atcaggtata catccgcaag tcgtaacata
     4441 taggtattaa tctctgtatg ctgctgcgtc accttaccat cattatcttc cggacggccc
     4501 accacatatt tcttcaccca tgcccttgca ttgtatcgct ccgtacccac gtagttccag
     4561 ggcacctgca attcctgtat gatcttcttg ccgggattat tgggatcatc taccgactga
     4621 tggatatagg aataatgatc accagggaac atgaacgttc ccttacgacg cttatcatct
     4681 atcctgtata atttcagctg atctaaggat gccccgagat ctcctcccca accatcaccg
     4741 aatcctgtta tttcggaacc ataggccagg aatgcctgca cactgttctg tgtcccccag
     4801 tcgccatcat acttccattg taaggcaaac aggctctctg aattattgtt gttcttcacc
     4861 aggaagaggt cttcgtaatt atccatcaat gccgcaccac tgttcataat cacatcattg
     4921 gcataccagg cggcactgtc cagatctgtc tgattctttg aaccggaaat accggcgcgt
     4981 gtcaggtaca ttttcgccag catcccttcc gccgcccact ttgtcagacg ccccttctgc
     5041 atcggtgcag ccggaagatt ttctgcggca aaacggatgt cacggatgat aaattcccat
     5101 acagatgcta tagtattacg gctgatagaa gtatctgtca gcaatacttt attatctgcg
     5161 atgatcggca ctgctcccca gttctgtacc aggtaagaat aagccacacc acgcataaaa
     5221 cggccttctg caatacctgc ctgtttcaca ttctcaggta ccgtcggcgc tgtataagta
     5281 accaggttgc tgataatctg attggcctgt gccaccacat tgaaaaaaga agtccaggaa
     5341 ctatatactt ccggtgtaac atccgtcgtc tgcatacgga tattatccac ctggtaggaa
     5401 cccgacatca atatgcccgc tctgccatct ccgataccat gagaagcttt atcgttataa
     5461 gcaaaccata caatgttgta cagcggggcc gttccggcga gtatctgatc agtcgtctga
     5521 tagaagttca catctacgat agcgtcttcc ggtggcctgt tcaggaagtc tttactacaa
     5581 cctgcggcga aaagcgtaca ggcaagggcg atcagatata tatgatagtt tgtctttttc
     5641 atactgtcag ttttaaagct cattaaaaat caaccgccac acttgcgcta tacaagcggg
     5701 tcaatggata gcgaccggca tccacaccaa tcagctgact gctcagctgc acttccttac
     5761 cgagataaga acctacttca ggatcgtatc ctttgtattt ggtgaaagtg gccaggttct
     5821 gtacacctgc gatcaggcgg atgtttttaa cgacagactg ttgtctcagt aatgcatgtg
     5881 gaatgttata tcctaactgt acattcttaa tgcggatata agatccgtct tctacataga
     5941 ggttcgtaaa acggttgccg ttaccgttta catctgtgcc tacaatcctg ggtacattgg
     6001 cgccgggatt ctctaagatg gtcttaccac ctacatctcc gacgcgtgca taattaaatg
     6061 attcctgtaa caagttccgg ccgagattga tattattcgg attcgtattc tcaaaacgga
     6121 gataattgaa gatgtcattg ccctgtgcag cggtcatcaa tacactcagg tcaaatcctt
     6181 tccatgaaaa agtatttgtc aaaccaaaag tcagctttgg ccaggggtta ccgataaatg
     6241 tctgatcacg tgaatcgatg atattatccc cattcaggtc tttgtatttg atatcgccca
     6301 cccatacgcc accgtcttta gccacaggta aacgggtacc gtcagattgt gcaggaatag
     6361 cgctgctgtt gatttcatcg acagactgaa acagtccttc tgcgacataa ccatagaact
     6421 gccagggcgc atcgccgatc acagaacggg aggtaaagtt attcatgaac caggcagacc
     6481 ttgacaggaa agcagcatca gaatagaact tcgtgatctt tgttttgaaa gaagagatat
     6541 tgaaattggt cctccagctg aaaccctgtt tgttatctat attaaccgta ttcagtgtaa
     6601 taccaaaacc tttgttctgc atcgccccga tatttacaat tggagcattg atagcgcctt
     6661 ctccctgtgt acccatatag gcaggcaatg gattaggcat cagcaggttg tcagttttct
     6721 tgatatagaa atcaccttcc agttgtatac ggtcttttaa tacactcatg ttaaaaccga
     6781 tgttctttgt ttcggtggat tcccatttga gtccggagtt accatactgt ccggtacgga
     6841 aacctgcgcc ccatggcgta gtcacagaag tcagggaaga gaactgtgca ccaccgctac
     6901 cattgttacc ggtcgtacca tattctgcac ggatcttcag ttcgttgata aagggtaatg
     6961 atttcataaa ttcctcccct gtcagacgcc aggctaccga tacagaagga aaatatcccc
     7021 atctgtcatc tgcaccaaag ttggaggaac catctgctct gccagccagt tggacgatat
     7081 acttgttatc gtacgtgtag ttaacacggc cgagataaga ttcaagtgca cccgatcctt
     7141 tgtaactacc cgttgtttgt cctaaggcat tacccaggtt gagagaaggg atactgttgc
     7201 tggcgaatcc tacacgctgt gcagagaaac cctgatagtt ccatgcctgt gcctcgtggc
     7261 tcaccatcac actgaaacta tgcttaccga tatcacggga gtattgcagt aattcgttca
     7321 ggttccagta gaagttcttt ccgttggata ctgcgagcga agctttctca ttgacattat
     7381 aacctaactg ataggtagga ataaacttgc tgccatctgt atattcgaaa ttcccgttaa
     7441 agctggtgcg gaaggtcagt ccttttatga tcgagatttc ggcagtagcg ccgcccagtc
     7501 caccggtacg tttataatca ttgctcacaa gactggcgat tgcaacagga ttcagcggcg
     7561 catatttcgc attggaacca tactcatttt ccgtagcacc gccccagctg ccatctgcat
     7621 ttttcacggg aatattaggg gccaggttaa tggcatttct gattacgtct tcactggtag
     7681 acgccagttt ttccttcgtc tgatagaagt tcagggacgt actcagcttc agccatttga
     7741 aagcctggtt atccaggttc aggcggaaag agtaacggtt gaaatcagaa ccgattgcca
     7801 ccccttcctg gtcaaaatac tcgcctgaca tataataggt ggtattgctg gcgcctccgc
     7861 tgatattcac ctggtgcttc tgtaatgaag cagtacggaa cagggcatcc tgccagttcg
     7921 tccccttccc taacacaccg ggattctgaa attccggtgt aggggtacgg ttcagcaact
     7981 gggctatttc attgttcatg atggcaaact gttgcaatgt catggtattg actgcctccg
     8041 gtttgtcctg cagcgaatag agatagttat aagacagttt catctgtccg gacttccctc
     8101 ttttggtagt caccaggatc accccattgg tggcccggga accatatacc gcagtggcag
     8161 aaggtccttg cagtatctct aaggactcta tatccgaagg attgatccct gccagcggat
     8221 taacagaact ggtcgctcca taagacaccg tagccggttg catctgtacc ccatcgatga
     8281 catacagcgg ttcattggta ccgctgaggg tattaacacc acggatattc acggagatac
     8341 caccacccgg ttgcccggag ttttgtgtaa catacacacc ggcggcacgg ccctgtatag
     8401 cctggtcgat ggtggtattg atggtacggt tgacttctgt ggaggtaatg gagacctgcg
     8461 cactgctctg gtctgttttc ttcattttac catacccgac gaccaccacg tcattcagtt
     8521 tgcggtaatc ttcctgcatc actacattca cagtggcgga attacctacc ttgaattccc
     8581 gggtaatgaa acccatggag gcaatattaa ttacctctcc cggagcagcc gggatactaa
     8641 aattccctgc cccgtcagtt gtggtcattc tttttgtccc tttaatagta attgaagccc
     8701 ccggaacagg tgtgcctgtt tctccggcgg taacgctgcc ggagatcttt cgtcccgggt
     8761 cagactgggt ttgtgcttgc gcaggcatag tgacagccca aaagaaaatc attacccata
     8821 ccgtcaggta cgattttcca gtaatactgg ctcgtttcat agcgtggaag aattaagttt
     8881 ttagattaat gcgcgattcg tttgattttg gtcatcattg ctcatatcgt gttccccttg
     8941 taggataaaa gtatcatccc tccgggagaa agagggctgt agaatgttta ttaaatagga
     9001 taaaatgttg caggaggggt atcaaatgtt gctttacggg catcatttat tgcaatacct
     9061 actttcgggc cgcggttgca taggcagagg gcagcatatt ataagccatt ttgaagtact
     9121 tggcgaagta tttcgggttg ttgaatccta cctcataggc gacctcggta acgttcattt
     9181 cggttttaga taataactgt gcagcccttt tgatacggat catacgtata aactctaccg
     9241 gcgtctgacc ggtcaggttg aaaatacgac gatacaggga gacccggttc atataaagtt
     9301 cccggctaag ttcttctacg gagaacccgg cattggacag attctgttct actatttcca
     9361 gcacccgacg gaggaacttc tcattagggg atgcctcatt ttcagcgttt tgcagttccg
     9421 gcagactcac ctgatgtttc gccggcaatg gtctggccag cagattacgt accctggata
     9481 acatgatctc aaaattgaaa ggttttacca ggtaatcggc tgccccggct tccagtccgc
     9541 ggagctgttc ctgttctccg gcagctgccg ttaccaggat gacagggata tgtttggtcc
     9601 gcgggtcatt tttgatcttc ctgcacaggt caattccgtt catgcccgac atattcacat
     9661 cactcatgac cagatccgga tgccctgaca gggttttctg ccagccggca ataccatctg
     9721 ctccttctat aatatgataa cagtctttca ggttctcctt caggtaaaaa cggaagtctt
     9781 cattgtcttc tatcaggagg acggtttgcc gttgggtatc ggtggccagc tcctcttctg
     9841 acagttcttc cggcagctct tccgcgaaca ggggatcttc tgtcaatagc tggtctttta
     9901 cgccttcctg cggctcgtct gccacctccg gctgttcaca ggtctctaaa ggcagtctta
     9961 ccgtaaaaca gctgccttta ttcacctcgc tctctacggt gatcgttcca ttattcagtt
    10021 tcacaaattc acgggtaata gctagtccga taccactccc cctgttcatc aaccctcccg
    10081 gcatatcact ctggaaaaac tgttcaaata ccttttcatg tctttcctca gggatgccga
    10141 taccggtatc tcttactttc atttccagcc aggtcttctc ttgttcatct ttattactgt
    10201 ttacctccac atgcaccgct ccgccgcttg gcgtaaactt aaaagcattg gacaggagat
    10261 taaacaggat cctttctatt ttatcattgt cgaaataggt atagacatgc ggagcattgc
    10321 ttttatagga gaagaggatc tgtttccttt ctgccagatc agcgaatgaa aaagttactt
    10381 cccggataaa cacagctata tcgccccagg tagggtttaa acgcagctcc tgcatttcca
    10441 tcttccggaa atccattagt tgattcacca gtatcaataa tcgttttgca ttccggtaga
    10501 tcagctggaa cttacctttc tctttttgtt caccgctttg ctgcataatc tcttccagtg
    10561 gtgacaggat cagggagacc ggtgttctga actcatgact aaggtttgta aacagacgga
    10621 tcttcatcat atccatttca tgcatacgcc tggcttcctg tctttcctgt tccagtgtaa
    10681 agcgcttatg cgcccttctg atcacactac ggcgcagcag taataatatg gccacggtca
    10741 aaagtacata gatgatatag gccagcggcg ttttccagaa aggcggtttt acaataatct
    10801 tcagtgaaat gccctcttca ttccaaaaac catcttcatt ggccgccttc acctgtaagg
    10861 tataagtacc gggattgata ttggtatagg taatacgccg ggtgctgcca tctgcgatca
    10921 accagttatc attaaactga tccaggcgat acgcatattt attcttctcc gtattgataa
    10981 aattcagtgc ggcaaattca agcgaaaaat cgttttcatt atgtttaagc acaatttctt
    11041 tggtgacaga taaggcttcc ggcaacaata ccctgtcatg cacttttgca ttgacttcaa
    11101 tattacggtc gaataaacgg agtccggtaa ataccacatc aggacgtgta ttattccgtg
    11161 gcagagaaga aggatcaaac aggttaaacc catcagcacc accgaagata agttcgccgg
    11221 tactgagttt aaatgccgca ttcacattga atgccttgct ttgcaaaccg tctttatcat
    11281 cgtaattccg acagctgatg ctgagtcctt ccgggccatc ctttaccgcg atccggctaa
    11341 gtccgttgga agtactcgcc catagatacc cttcattatc ctccagcatg gtgatgatgt
    11401 tattatccgg cagaccgtcc ttcaccgtaa acgatctgaa ttgctgtact ttttcatcaa
    11461 atacattcag accggcacgg gtacctgccc acatatgccc tcgtttgtca tagagcagcg
    11521 aactgacatt atcattactc agttgatggg tggaactgag atagtgtaca aagacgcctt
    11581 ttgaattatc cagcacgtca ataccatagg cagtggcgat ccacaggttc cccctgttgt
    11641 cttctgcgaa tccggagata taattggaat gaacggatgc cggcatattg acattgttgt
    11701 gatagaagat gccattacca ggatcaaacc ggtccagtcc tccgcccagg gtacctaccc
    11761 agaaattgtt ccgctgatca cggtatatct tccagacgga cttattcgcc agactattcg
    11821 gatcatcctc ctcatggcga taatggttaa aacgtccgtt gctgtagaag tccattcctc
    11881 cgaaataata accgatccag agatcattgt agttattcac atagagactg acgatcacat
    11941 ctttgctgat gctgttatca ttggaaggat catgctgaaa gcgtttgaag gtctgattga
    12001 cacggtcgaa gtaaatcagt ccgccgccat tcgtaccaat ccagatattc cctttttcat
    12061 cttctgcaaa gcaattgaca tcattataac tcaggctgtt attatcagca tggctatgct
    12121 tatacaaggg aaatttcacc atattctcag tgaaataact aagtcctctt ttgtaggtgc
    12181 cacaccagat aatgccgaaa ttatctttgt agagtgcata gacggcattc tctgcaatgg
    12241 tcttcagatc gccttcttta ttcacaagaa agcgggactt aaaattgtta ttcttatcaa
    12301 tcaggttaat tcctccgtga tctgtaccaa tccagatgaa atgtttatcg tcttccacaa
    12361 tactattgac aatatcattg ttcaaagccc ctgttttact ggatagcatt ttcactttac
    12421 catccgtccg gttcagataa gccaccccga aatcacttcc cggcatatac acccacatat
    12481 cctttgctgc gtctatgaag atgcgcaggg ctaagggagg tttaccgatg tatttcctga
    12541 tattggaatt gcgatagata atcttattac tggcaatgtc cagtttttcc acatctccgt
    12601 tcagataaag gataaccagc agcttgtctc cttccccctg cagatcggca atagccgcat
    12661 tggccctatc cggcagtaat attttagtgg tacggccggt gctgtctgtt ttgtataacc
    12721 gggcatcatt ataagcgatc caccagttgc ggcctgtttg tgcgacactg gtgatgccgt
    12781 attcagacaa accttttttc ttcagccagg tagtcgcatc ggagaactgt tctgtgaccg
    12841 gattatagaa attgtccccg ttccttgttc tgataaaaag ctgattattc ggtgcgggat
    12901 agataccggt gatgtagtcg tcgttaataa cgccaggttc tgcactatgc cggaatgttt
    12961 taaacgcata accgtcataa cggtttaatc cgctcatggt accaaaccac ataaatcccc
    13021 tggcatcttt ataaatggaa tttacctggt tattggataa accattgttc acatctaaag
    13081 aagagaactg gtaggatggc tgtgcatagg catagcttac cagcaataac agtggaagca
    13141 gcaaattttt cattaacat
//
