LOCUS       NC_002505               5730 bp    DNA     linear   CON 10-MAR-2020
DEFINITION  Vibrio cholerae O1 biovar El Tor str. N16961 chromosome I, complete
            sequence.
ACCESSION   NC_002505
VERSION     NC_002505.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN02603969
            Assembly: GCF_000006745.1
KEYWORDS    RefSeq.
SOURCE      Vibrio cholerae O1 biovar El Tor str. N16961
  ORGANISM  Vibrio cholerae O1 biovar El Tor str. N16961
            Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales;
            Vibrionaceae; Vibrio.
REFERENCE   1  (bases 1 to 5730)
  AUTHORS   Heidelberg,J.F., Eisen,J.A., Nelson,W.C., Clayton,R.A., Gwinn,M.L.,
            Dodson,R.J., Haft,D.H., Hickey,E.K., Peterson,J.D., Umayam,L.,
            Gill,S.R., Nelson,K.E., Read,T.D., Tettelin,H., Richardson,D.,
            Ermolaeva,M.D., Vamathevan,J., Bass,S., Qin,H., Dragoi,I.,
            Sellers,P., McDonald,L., Utterback,T., Fleishmann,R.D.,
            Nierman,W.C., White,O., Salzberg,S.L., Smith,H.O., Colwell,R.R.,
            Mekalanos,J.J., Venter,J.C. and Fraser,C.M.
  TITLE     DNA sequence of both chromosomes of the cholera pathogen Vibrio
            cholerae
  JOURNAL   Nature 406 (6795), 477-483 (2000)
   PUBMED   10952301
REFERENCE   2  (bases 1 to 5730)
  AUTHORS   Heidelberg,J.F., Eisen,J.A., Nelson,W.C., Clayton,R.A., Gwinn,M.L.,
            Dodson,R.J., Haft,D.H., Hickey,E.K., Peterson,J.D., Umayam,L.A.,
            Gill,S.R., Nelson,K.E., Read,T.D., Tettelin,H., Richardson,D.,
            Ermolaeva,M.D., Vamathevan,J., Bass,S., Qin,H., Dragoi,I.,
            Sellers,P., McDonald,L., Utterback,T., Fleishmann,R.D.,
            Nierman,W.C., White,O., Salzberg,S.L., Smith,H.O., Colwell,R.R.,
            Mekalanos,J.J., Venter,J.C. and Fraser,C.M.
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2000) The Institute for Genomic Research, 9712
            Medical Center Dr, Rockville, MD 20850, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 03/10/2020 04:57:55
            Annotation Pipeline               :: NCBI Prokaryotic Genome
            Annotation Method                 :: Best-placed reference protein
            Annotation Software revision      :: 4.11
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
            Genes (total)                     :: 3,735
            CDSs (total)                      :: 3,608
            Genes (coding)                    :: 3,527
            CDSs (with protein)               :: 3,527
            Genes (RNA)                       :: 127
            rRNAs                             :: 9, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 98
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 81
            CDSs (without protein)            :: 81
            Pseudo Genes (ambiguous residues) :: 0 of 81
            Pseudo Genes (frameshifted)       :: 64 of 81
            Pseudo Genes (incomplete)         :: 12 of 81
            Pseudo Genes (internal stop)      :: 9 of 81
            Pseudo Genes (multiple problems)  :: 3 of 81
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence was derived from
            AE003852.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Annotation Pipeline (PGAP)
            set; GeneMarkS-2+
            repeat_region
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..5730
                     /organism="Vibrio cholerae O1 biovar El Tor str. N16961"
                     /mol_type="genomic DNA"
                     /strain="N16961"
                     /serotype="O1"
                     /db_xref="taxon:243277"
                     /chromosome="I"
                     /biotype="El Tor"
     gene            complement(1..1296)
                     /gene="cod"
                     /locus_tag="VC_RS06245"
                     /old_locus_tag="VC1280"
                     /old_locus_tag="VC_1280"
                     /db_xref="GeneID:2614734"
     CDS             complement(1..1296)
                     /gene="cod"
                     /locus_tag="VC_RS06245"
                     /old_locus_tag="VC1280"
                     /old_locus_tag="VC_1280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001881046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBM12|CE4"
                     /protein_id="WP_001881046.1"
                     /db_xref="GeneID:2614734"
                     /translation="MDTKMKLKKLALFTAISLAISGHSFANSTPKGTIYLTFDDGPVNA
                     SVEVIKVLNQGGVKATFYFNAWHLDGIGDENEDRALEALKLALDSGHIVGNHSYDHMIH
                     NCVEEFGPTSGADCNATGNHQIHSYQDPVRDAASFEQNLITLEKYLPTIRSYPNYKGYE
                     LARLPYTNGWRVTKHFQADGLCATSDNLKPWEPGYVCDPANPSNSVKASIQVQNILANQ
                     GYQTHGWDVDWAPENWGIPMPANSLTEAVPFLAYVDKALNSCSPTTIEPINSKTQEFPC
                     GTPLHADKVIVLTHDFLFEDGKRGMGATQNLPKLAEFIRIAKEAGYVFDTMDNYTPRWS
                     VGKTYQAGEYVLYQGVVYKAVISHTAQQDWAPSSTSSLWTNADPATNWTLNVSYEQGDI
                     VNYKGKRYLVSVPHVSQQDWTPDTQNTLFTAL"
     gene            1539..1844
                     /locus_tag="VC_RS06250"
                     /old_locus_tag="VC1281"
                     /old_locus_tag="VC_1281"
                     /db_xref="GeneID:2614735"
     CDS             1539..1844
                     /locus_tag="VC_RS06250"
                     /old_locus_tag="VC1281"
                     /old_locus_tag="VC_1281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000722179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gnl|TC-DB|Q9KSH5|4.A.3.2.6"
                     /protein_id="WP_000722179.1"
                     /db_xref="GeneID:2614735"
                     /translation="MKKILLCCSAGMSTSMLVKKMQQAAESKGIECKIDALSVNAFEEA
                     IQEYDVCLLGPQVRFQLEELRKTADEYGKNIAAISPQAYGMMKGDEVLQQALDLIN"
     gene            1932..3263
                     /locus_tag="VC_RS06255"
                     /old_locus_tag="VC1282"
                     /old_locus_tag="VC_1282"
                     /db_xref="GeneID:2614736"
     CDS             1932..3263
                     /locus_tag="VC_RS06255"
                     /old_locus_tag="VC1282"
                     /old_locus_tag="VC_1282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017100048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gnl|TC-DB|Q9KSH4|4.A.3.2.6"
                     /protein_id="WP_000780651.1"
                     /db_xref="GeneID:2614736"
                     /translation="MKLYDAIIGIVEKHIAPIAAKVGNQPHVRAMRDGFIVAMPFIIVG
                     SFILIFAFPPFAEDTTNVFGRVWLNFATTHFDIIMMPFNMSMGIMTIFVSLGVAYSLAK
                     AYKMDGITSAVLSLMSFLLVAAPAKEDSLSMAHMGGTGIFTAVMCAFFAVELYRFMKKH
                     NITIRMPEQVPPAIARSFEVLLPVLAIFLTLYPLSLFVQAEYGMLIPDAVMAMFKPLIS
                     ASNTLPAIIGALLVCQLLWFAGIHGAAIVVGLLSPIFLTNISANIDAFVTGQPVPNIFT
                     QPFWDFYIFIGGSGATLALVILMSFSRSAHLKSIGRMSAVPGFFQINEPVIFGSPVVMN
                     PILFLPFVFAPVINATIAYFAIQLGFVGMGVATTPWTTPAIIGASWGSGWTFTPVLLVV
                     GLLILDLLIYLPFFKMFEKQVLEQEQPVESKVKAAQPGRQGVTA"
     gene            3310..3645
                     /locus_tag="VC_RS06260"
                     /old_locus_tag="VC1283"
                     /old_locus_tag="VC_1283"
                     /db_xref="GeneID:2614737"
     CDS             3310..3645
                     /locus_tag="VC_RS06260"
                     /old_locus_tag="VC1283"
                     /old_locus_tag="VC_1283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017100049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gnl|TC-DB|Q9KSH3|4.A.3.2.6"
                     /protein_id="WP_000434480.1"
                     /db_xref="GeneID:2614737"
                     /translation="MEQELIVMEIICNAGEARSLCYEALRLARTRSFEQAEEKLCQAKE
                     CLNRAHLIQTQLIEADQGEGKVPMTLVMVHAQDHLMTTILAQEMATEMVALHKHLAGEE
                     AKCLEMH"
     gene            3627..4949
                     /locus_tag="VC_RS06265"
                     /old_locus_tag="VC1284"
                     /old_locus_tag="VC_1284"
                     /db_xref="GeneID:2614738"
     CDS             3627..4949
                     /locus_tag="VC_RS06265"
                     /old_locus_tag="VC1284"
                     /old_locus_tag="VC_1284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000089159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH4"
                     /protein_id="WP_000089165.1"
                     /db_xref="GeneID:2614738"
                     /translation="MSRNALKLAVIGGGSSYTPELVEGVLKRLDFLPVKQLHFVDIEAG
                     AEKLQIIRDLAQRMVDKVGADIEIKAGFDRREAIAGADFVMTQFRVGGLAARANDERIP
                     LKYDVIGQETTGPGGFAKALRTIPVILDICRDIEELAPNAWMLNFTNPAGLVSEAVSKY
                     SKVKSIGLCNVPVSMQMMIAEMMACEPQDLQLEFAGLNHLVWVHQAWLDGQNITQTVLE
                     KVGDGANFSMKNIWEEPWDPEFLKALGAIPCPYHRYFYQTDAMLAEEKKSAQEKGTRAE
                     QVMVTEKALFELYQDPHLAHKPKELEARGGAYYSDASLNLVDAIYNNRNSIHVVNVQNH
                     GAISSLPHDAVIECSAVVGSWGAKPIAVGELSPKISGLLHQVKAYEQLAIEAAVHGDYH
                     LALMALTNNPLVPDIGRAKAILDDILRENAVYLPQFKLTTW"
     gene            4972..5730
                     /gene="chbG"
                     /locus_tag="VC_RS06270"
                     /old_locus_tag="VC1285"
                     /old_locus_tag="VC_1285"
                     /db_xref="GeneID:2614739"
     CDS             4972..5730
                     /gene="chbG"
                     /locus_tag="VC_RS06270"
                     /old_locus_tag="VC1285"
                     /old_locus_tag="VC_1285"
                     /EC_number="3.5.1.105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000864255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chitin disaccharide deacetylase"
                     /protein_id="WP_000864259.1"
                     /db_xref="GeneID:2614739"
                     /translation="MKVIFNADDFGLTQGVNQGIVKAHLDGVVKSTTLMVGMPAEQHAV
                     QLAKQLPDLKIGLHLRFTAGRPLTGERNLTDEHGVFTAYRDFWQRRDYQPEAIYHEAIA
                     QVEHFLKLGLTLSHLDSHHHAHTHPQLAPIIYEVAKKYHVPLRDIGMAGEEAFGCRYHF
                     TDFFYDQRLGIDPLMKHLLELKERFDLVEVMCHPAFVDPLLEKCSGYAKQREEELHILT
                     SAQLIQLLVAHDIEITDYSALISAPLHSCV"
ORIGIN
        1 ttataaagct gtgaataagg tgttctgagt gtctggtgtc cagtcttgtt gtgaaacatg
       61 tgggacactg actaaatagc gtttaccttt gtaattgacg atgtcgcctt gctcatagga
      121 gacattgagt gtccagtttg tcgcagggtc ggcgttggtc caaaggcttg acgtggatga
      181 tggagcccaa tcctgttgcg cagtgtgact aatgaccgct ttatacacca caccttggta
      241 cagaacatat tctcccgctt gatacgtttt acctacgctc caacgaggag tgtaattatc
      301 catcgtatcg aaaacataac ctgcttcttt ggcaatccgg ataaactcgg caagtttagg
      361 taagttttgt gtcgctccca taccgcgttt gccatcttca aataagaaat catgggtgag
      421 cacaatcact ttatcggcgt gcagtggggt gccacaaggg aactcttgtg ttttcgagtt
      481 aattggttcg atagtggttg gtgagcaact atttaaggct ttatccacat aggccaaaaa
      541 gggaacggct tcggttaagc tgttggcagg cataggaata ccccagtttt cgggggccca
      601 atccacatcc catccgtgag tttgatagcc ttgattagca agaatattct gtacttgaat
      661 cgaggctttc acactgtttg atgggttagc tggatcgcac acataacccg gctcccaagg
      721 ttttaaattg tcggatgtcg cgcataaacc atcagcttgg aagtgctttg tgacacgcca
      781 accgttggta tagggtaggc gagctaactc ataccccttg tagtttggat agctacgaat
      841 agtaggcagg tatttttcta atgtgatcaa gttttgctca aaactggccg catcacgaac
      901 gggatcttga tacgagtgga tttgatggtt accggttgca ttacaatctg cgccactggt
      961 ggggccaaac tcttccacac agttatgaat catatgatcg tagctgtggt tgccgacaat
     1021 atgacctgaa tctagagcta actttagagc ctctagagca cgatcttcat tttcatcacc
     1081 gataccatcc aagtgccaag cgttaaaata aaaagtggct tttaccccgc cttggtttag
     1141 aaccttaatg acttctactg acgcattgac cgggccatca tcaaaagtta aataaatcgt
     1201 gcccttaggg gtactgtttg caaaagaatg accagaaatg gctaacgata tcgcggtaaa
     1261 tagagccaat ttttttaatt tcatcttagt atccattatt ttaaatcaga aatttaagag
     1321 tgacgttgct agtatttata ttgatagaaa taacaagtcc atctggtagg cttatatatt
     1381 tcttctcatt atcctatcca gaagtgcatc gataaaaata gcgctaacta tccgaaatgg
     1441 gattttgttc acgaataacg caaccggttg cgctttttaa tgcggattta ttttgctaca
     1501 gtttttaggt cgatatttaa acaagggaag tgtagagcat gaaaaagatc ctactctgct
     1561 gtagtgctgg tatgtctacc agtatgttag tgaagaaaat gcagcaagct gctgaaagta
     1621 aaggcattga atgcaagatt gatgcgttat cagtgaatgc atttgaagag gccatccaag
     1681 aatatgatgt ttgcttatta gggcctcaag tccgttttca gttggaagag ctacgcaaaa
     1741 cggccgatga atatggcaaa aacattgcag ctatctctcc tcaagcttac ggcatgatga
     1801 aaggtgacga ggttcttcag caagctttag atttaattaa ctaaatctgt ttttcggaca
     1861 atattttcac tcaatcctca ttaattaaat gaggataggg aactctttat cttaaatata
     1921 aggtgaatcc tatgaagctt tatgatgcga taattggaat cgtagaaaag catatagccc
     1981 ccattgcagc aaaagtgggg aatcagcctc atgtacgtgc catgcgtgat ggttttattg
     2041 tggcaatgcc atttattatt gtgggtagtt ttattttaat ttttgcattc cctccttttg
     2101 ctgaagatac caccaatgtt tttggtcgcg tgtggttaaa cttcgctacg acgcatttcg
     2161 atatcatcat gatgccgttt aatatgtcga tgggcattat gaccatattt gtctcgttgg
     2221 gtgtagcata cagcttagcg aaagcttaca aaatggacgg tatcacgagt gcagtactgt
     2281 cactgatgag ctttttgttg gtcgcggcac ccgccaaaga agacagtcta tcgatggcgc
     2341 atatgggcgg cacagggatt ttcacggctg ttatgtgtgc tttttttgcc gtcgaactgt
     2401 atcgctttat gaaaaagcat aacattacca ttcgtatgcc agagcaagtt ccacctgcga
     2461 ttgctcgctc attcgaagtt ttgttgcctg tcttggcgat tttcttgacg ctttatccac
     2521 tgagcctttt tgtacaagcc gaatatggca tgttgatccc tgatgccgtg atggcgatgt
     2581 tcaaaccgtt gatcagtgcg tcaaacacat tgccagcgat tatcggtgcg ctgctggtgt
     2641 gtcaattgtt atggtttgcg ggcattcatg gggctgcgat tgtggtcggt ctgctatctc
     2701 ccatcttctt aaccaatatc agtgctaaca ttgatgcgtt tgttactggg cagcccgtcc
     2761 cgaatatctt cacacagcca ttctgggatt tttacatctt tatcggtggt tcaggtgcaa
     2821 ccttagcgtt agtgattttg atgtccttca gccgctcagc tcatttaaaa agcatcggtc
     2881 gtatgagtgc ggtaccagga ttcttccaaa ttaacgaacc tgtgattttt ggtagtccag
     2941 tggtgatgaa cccgatttta ttcctgcctt tcgttttcgc tcccgtaatc aatgccacca
     3001 ttgcttattt tgcgattcag ttgggctttg tcggtatggg agtagcaacc acgccatgga
     3061 caacaccggc cattatcggt gcgtcatggg gtagtggttg gacgtttacg cctgtgttgc
     3121 tggtcgtggg tttactcatc cttgatctgc tcatttactt acctttcttc aaaatgtttg
     3181 agaagcaagt gcttgaacaa gagcaacctg tggaaagtaa agtcaaagca gcgcaaccag
     3241 gtagacaagg cgtcacggca taagcagttt aaggctgccg gtgggcagcc ttagcttcgg
     3301 gagagagaaa tggaacaaga acttatcgtg atggaaatta tttgcaacgc cggtgaagcg
     3361 cgaagcttgt gttatgaagc attacgttta gcgcgtactc gatcttttga gcaggcagaa
     3421 gagaaattgt gtcaggctaa agagtgctta aaccgagctc atttaattca aacacaattg
     3481 attgaagccg atcagggtga aggcaaagta ccaatgacct tggtgatggt gcatgctcaa
     3541 gatcatttaa tgacgacaat tctggcacag gaaatggcga ctgaaatggt ggctttacat
     3601 aaacacttgg cgggtgagga agcaaaatgt ctcgaaatgc attaaagctg gcagtcatcg
     3661 gcggtggcag tagttacacc ccagagcttg tggaaggggt tctcaaaaga ttggattttc
     3721 tgccagtgaa gcagttgcac tttgtggata ttgaagccgg tgcggaaaaa ttacagatca
     3781 ttcgagatct tgcgcagaga atggtcgaca aagttggagc tgacattgaa attaaagcgg
     3841 gctttgatcg ccgagaggcg attgccggcg ctgatttcgt tatgacccag tttcgggttg
     3901 gggggcttgc cgctcgcgcg aatgatgaac gaattccact gaaatatgat gtgattgggc
     3961 aagaaaccac agggcctggt ggttttgcca aagcacttcg aacgatccca gtcatactgg
     4021 atatttgccg agatattgaa gagctagcac ccaatgcctg gatgctcaac tttaccaatc
     4081 ctgcgggctt ggtctcggag gcagtcagta aatactcaaa agtcaaaagc ataggattat
     4141 gtaatgttcc cgtttctatg cagatgatga ttgctgaaat gatggcctgt gaacctcaag
     4201 accttcagct cgagttcgct gggctgaacc atttagtttg ggtgcaccaa gcttggttgg
     4261 atggtcaaaa tatcactcaa accgttttag aaaaggtggg tgatggcgcc aatttcagca
     4321 tgaaaaatat ctgggaagaa ccttgggatc ctgagttctt aaaagcgtta ggcgcgattc
     4381 cttgccctta tcaccgctac ttttaccaaa cggatgctat gttggcagaa gagaaaaaaa
     4441 gtgctcaaga gaaaggaacg cgagctgagc aagtgatggt cactgaaaag gccttatttg
     4501 agctctatca agatccacat ctggctcata agcctaaaga gttagaagcg cgtggcggtg
     4561 cttattattc ggatgcctcg ttaaatcttg ttgatgccat ctacaataat cgcaatagta
     4621 ttcatgtggt taatgtgcag aatcatgggg cgatcagttc attacctcat gatgccgtga
     4681 ttgaatgcag tgcggtggtg ggcagttggg gagcaaaacc gattgcggtc ggagaacttt
     4741 caccaaaaat cagtggattg ctacatcaag tgaaagccta tgagcagctt gcgatagaag
     4801 ccgcagtaca cggtgactat caccttgctt taatggcttt aacgaataac ccattggtgc
     4861 ctgatattgg tcgggcgaaa gccattttgg atgatattct gcgtgaaaat gccgtttatc
     4921 taccccaatt taaactcacc acatggtaac ggtaataagg tgaatctctc gatgaaggta
     4981 atttttaacg cggacgattt tggtttaact caaggtgtca accaaggtat tgtcaaggcc
     5041 caccttgatg gggtcgtaaa atcaaccact ttgatggtgg gcatgcctgc agagcagcat
     5101 gcggttcaat tggcaaaaca gcttcccgac ttaaaaattg gccttcatct gaggtttaca
     5161 gcaggacgcc ctttaacggg agaaagaaac ttaaccgatg aacatggtgt cttcaccgct
     5221 tatcgtgatt tttggcagcg tagagactat caacctgagg cgatatacca tgaagctatc
     5281 gcccaggttg aacattttct aaagcttgga ctcactttaa gtcatcttga tagccatcat
     5341 cacgcccata ctcatcctca attggctccg atcatttatg aagtggctaa aaaataccat
     5401 gttccactgc gggatattgg tatggcaggg gaggaggcgt tcggctgccg ttatcatttc
     5461 actgattttt tctatgatca acgtttgggc atcgaccctt taatgaaaca tctgcttgag
     5521 ctaaaagaac gcttcgatct ggttgaggtt atgtgccatc ccgcgttcgt ggatccatta
     5581 ctcgaaaagt gcagcggtta tgccaagcaa agagaagaag agttgcacat tctaactagc
     5641 gcacaattaa tacaattgtt ggtagcgcat gatatcgaaa tcacggatta ctcggctttg
     5701 atttctgctc ctctgcactc ctgtgtatga
//
