LOCUS       CP007013               10378 bp    DNA     linear   BCT 18-FEB-2015
DEFINITION  Thermotoga maritima MSB8, complete genome.
ACCESSION   CP007013
VERSION     CP007013.1
DBLINK      BioProject: PRJNA63051
            BioSample: SAMN02261406
KEYWORDS    .
SOURCE      Thermotoga maritima MSB8
  ORGANISM  Thermotoga maritima MSB8
            Bacteria; Thermotogae; Thermotogales; Thermotogaceae; Thermotoga.
REFERENCE   1  (bases 1 to 10378)
  AUTHORS   Noll,K.M., Huntemann,M., Han,J., Chen,A., Kyrpides,N.,
            Mavromatis,K., Markowitz,V., Palaniappan,K., Ivanova,N.,
            Schaumberg,A., Pati,A., Liolios,K., Nordberg,H.P., Cantor,M.N.,
            Hua,S.X. and Woyke,T.
  CONSRTM   DOE Joint Genome Institute
  TITLE     Direct Submission
  JOURNAL   Submitted (17-DEC-2013) DOE Joint Genome Institute, 2800 Mitchell
            Drive, Walnut Creek, CA 94598-1698, USA
COMMENT     ##MIGS-Data-START##
            investigation_type           :: bacteria_archaea
            project_name                 :: Thermotoga maritima MSB8, DSM 3109
            collection_date              :: 1982
            lat_lon                      :: 38.3912 14.9676
            country                      :: Italy
            num_replicons                :: 1
            ref_biomaterial              :: DSM 3109, ATCC 43589
            biotic_relationship          :: Free living
            rel_to_oxygen                :: Anaerobe
            isol_growth_condt            :: 10360571
            assembly                     :: Newbler v. 2.3
            finishing_strategy           :: Level 6: Finished
            environment                  :: Mud
            sequencing_meth              :: WGS
            GOLD Stamp ID                :: Gi08995
            Current Finishing Status     :: Level 6: Finished
            Type Strain                  :: Yes
            Funding Program              :: DOE-CSP 2010
            Gene Calling Method          :: Prodigal 1.4, GenePRIMP
            Isolation Site               :: anaerobic marine mud
            Isolation Comments           :: isolated by Stetter
            Temperature Range            :: Hyperthermophile
            Temperature Optimum          :: 80
            Gram Staining                :: Gram-
            Sequencing Depth             :: 30x
            Diseases                     :: None
            ##MIGS-Data-END##
            ##Genome-Assembly-Data-START##
            Finishing Goal               :: Finished
            Current Finishing Status     :: Finished
            Assembly Method              :: Newbler v. 2.3
            Genome Coverage              :: 30x
            Sequencing Technology        :: 454; Illumina GAii
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider          :: NCBI
            Annotation Date              :: 12/19/2013 10:56:46
            Annotation Pipeline          :: NCBI Prokaryotic Genome Annotation
            Annotation Method            :: Best-placed reference protein set;
            Annotation Software revision :: 2.3 (rev. 421815)
            Features Annotated           :: Gene; CDS; rRNA; tRNA; ncRNA;
            Genes                        :: 1,932
            CDS                          :: 1,872
            Pseudo Genes                 :: 10
            CRISPR Arrays                :: 7
            rRNAs                        :: 3 ( 5S, 16S, 23S )
            tRNAs                        :: 46
            ncRNA                        :: 1
            Frameshifted Genes           :: 5
            ##Genome-Annotation-Data-END##
            URL -- http://www.jgi.doe.gov
            JGI Project ID: 403117
            Source DNA and Organism available from Kenneth M. Noll
            (noll@uconn.edu)
            Source DNA available from Kenneth M. Noll (noll@uconn.edu)
            Organism available from Kenneth M. Noll (noll@uconn.edu)
            Contacts: Kenneth M. Noll (noll@uconn.edu)
            Tanja Woyke (microbe@cuba.jgi-psf.org)
            Whole genome sequencing and draft assembly at JGI-PGF
            Annotation by JGI-ORNL
            The JGI and collaborators endorse the principles for the
            distribution and use of large scale sequencing data adopted by the
            larger genome sequencing community and urge users of this data to
            follow them. It is our intention to publish the work of this
            project in a timely fashion and we welcome collaborative
            interaction on the project and analysis.
            (http://www.genome.gov/page.cfm?pageID=10506376).
            Annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (released 2013). Information about the Pipeline can be
            found here: http://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Pipeline
            GeneMarkS+
            repeat_region
FEATURES             Location/Qualifiers
     source          1..10378
                     /organism="Thermotoga maritima MSB8"
                     /mol_type="genomic DNA"
                     /strain="MSB8"
                     /isolation_source="anaerobic marine mud"
                     /culture_collection="DSM:3109"
                     /type_material="type strain of Thermotoga maritima"
                     /db_xref="taxon:243274"
     gene            complement(1..1662)
                     /locus_tag="THEMA_05005"
     CDS             complement(1..1662)
                     /locus_tag="THEMA_05005"
                     /inference="EXISTENCE: similar to AA
                     sequence:RefSeq:YP_001244559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gnl|TC-DB|Q05839|8.A.9.1.1"
                     /protein_id="AHD18270.1"
                     /translation="MKKPFLLLAFVFLLFLTSCFQTSMSQSLVSSNPHSNSTNTDGTSS
                     NLEEVKYPVVYEIFIRSFYDRDGNGVGDLNGVSQKVDYLKELGVDAVWFMPFNEAVSYH
                     GYDITDYYNVEKDYGTMEDLENMIQVLHENGIKVIMDLVINHTSDEHPWFKDAVENTTS
                     SPYWDYYIMSLEDHSGQDHWHWKINSKGQKVWYFGLFGYNMPDLNHDSQKVREEVKKIV
                     DFWISKGVDGFRIDAAKHIYGWSWDDGIQESAEYFEWFRDYVLSKKPDAILVGEVFSGN
                     TYDLSLYPIPVFNFALMYSIRNYPEGQDGMIENNWVEESFLFLENHDLHRFFSHLQEHY
                     KKFSESDYEFIKKRAALWYFLIFTLKGSPVIYYGGEIGTRGFKWHGPVYDEPVREPMQW
                     YASGTGEGQTFWTKEVYKNAGITFGNADVDGCIYDDPYDGFSVEEQESDPKSLLNFIRF
                     ILNFRKDHDAILNGDQTIFRDWKNLIAFYRESSNEKLLVVLNPDPVWQNSFTFEENMTM
                     ILEVDFENFIWNESNVSFSAGESFTVDPMKAYIFKK"
     gene            1897..3075
                     /locus_tag="THEMA_05010"
     CDS             1897..3075
                     /locus_tag="THEMA_05010"
                     /inference="EXISTENCE: similar to AA
                     sequence:RefSeq:NP_229009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gnl|TC-DB|Q9S5Y1|3.A.1.1.22"
                     /protein_id="AHD18271.1"
                     /translation="MKRLLVLMLVVVSALVLSQTKLTIWCSEKQVDILQKLGEEFKAKY
                     GIPVEVQYVDFGSIKSKFLTAAPQGQGADIIVGAHDWVGELAVNGLIEPIPNFSDLKNF
                     YDTALKAFSYGGKLYGVPYAMEAVALIYNKDYVDSVPKTMDELIEKAKQIDEEYGGEVR
                     GFIYDVANFYFSAPFILGYGGYVFKETPQGLDVTDIGLANEGAVKGAKLIKRMIDEGVL
                     TPGDNYGTMDSMFKEGLAAMIINGLWAIKSYKDAGINYGVAPIPELEPGVPAKPFVGVQ
                     GFMINAKSPNKVIAMEFLTNFIARKETMYKIYLADPRLPARKDVLELVKDNPDVVAFTQ
                     SASMGTPMPNVPEMAPVWSAMGDALSIIINGQASVEDALKEAVEKIKAQIEK"
     gene            3152..4885
                     /locus_tag="THEMA_05015"
     CDS             3152..4885
                     /locus_tag="THEMA_05015"
                     /inference="EXISTENCE: similar to AA
                     sequence:RefSeq:YP_001244561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gnl|TC-DB|Q9X0T0|3.A.1.1.22"
                     /protein_id="AHD18272.1"
                     /translation="MKGLLKIFLILFLAVFNAGMVWAGIFLLQNSYYELGIVLLTLLVL
                     IDYFIFNPKAYPYRYTIPALILLFVLVLYPIYFTVKVAFTNYGTGHLMTKQEAIERILF
                     DPNYTYVPESAEPVEYMVFSVFNGLNPTEDFVVLFEKDGNIYIAERPVVTKRSGKEVLL
                     RESTLFPVKDGTAEVNGKVYEIVPWPASIKEVNAVYSDGKIYKPLYSPEEVSLKRYEPF
                     FKVNVVQKYLNRAEFWLEDQSYMFRIGENGEWNFYPVKRLYSLSFEESLENGRITTKLV
                     VKNNLTGRHLVEREGAFYDYDENGREFFVIGYMEYIGFKNFSRIFTDPKIAGPFFKVFT
                     WTFTWAALSVLLTFAIGLSLALVLNDKTLKGKNVYRTLLIIPWAVPAFISVLVWRNGMF
                     NETYGILNRFVLPFLGLDPVKWFNDPFWAKVAVLTVNTWLGFPYMMAVSLGALQSIPEE
                     LYEAAAIDGAGRWRRFWTITFPLLMTTVAPLLVGSFAFNFNNFVNIYLLTGGGPAMAGT
                     TTPVGHTDILISYVYKLAFEGGRGQDFGFASAISIIIFFLVGGISFVNFKLSGAFEEVS
                     E"
     gene            4885..7383
                     /locus_tag="THEMA_05020"
     CDS             4885..7383
                     /locus_tag="THEMA_05020"
                     /inference="EXISTENCE: similar to AA
                     sequence:RefSeq:ZP_10919534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gnl|TC-DB|Q9X2F5|3.A.1.1.22"
                     /protein_id="AHD18273.1"
                     /translation="MVRKKNRWLTHVLLTLLVVVVLFPIVWVVSTSFRRDEAAFSPKLF
                     SSRLTLQHYKDLVAPEKNLPVLIQEMQSLVSRVEPFDNVSREKADRLIEDRIRRFENYL
                     AETKKLLEDVNARNSKIEETLSQRFSDVLSYTKDVLEEAKKLTQEQMDKTPLPDSQRIA
                     VALYEKLKGKNFRSAEFQALKDVIEKVVGYSVENQDTLNDALSELGLVYEKEVGTLMKE
                     IEKLEGEIEILQREIAVLEKQKETLEKEILEKQKVLEVLKPDIDSVSEVLVKLKEMVHS
                     VRNSKVETAFPYEDSRLKSSLEKLLSELNTLYDKISAFSDLSDLSEKIFAMKSSLEEIN
                     NVVSEDGDISKKALYGSFVQSFEETVPIIEGIVEKVSDGIDDFVQKIKDLKDIENEIMV
                     LTAKLDGLEKSLNNVRSSLSEKEKEISSAKMYLDLKIFNHQIQSRIDSLESMKSFNNAA
                     QIKLLSIYKTLKNFVSSYVSEYGGDDFIGKIRKLAAKLSWIEDYRDLNRRIETGYKNAV
                     EIVEKAQNILDDFKGSYSNLLDLSFKGLYVSSEHLEMLYDLVKMNFVQEVLTNTAVASR
                     KAGTLMDTIPLKELKSDLKKIDGDLYRLAQIWEQKTKHYFLRWVMNSVIVAGLVSLITT
                     AVCALAAYPFSRMRFWGRQYGIMALLLIQMFPAIMYMVAIYGLLKLIGQFLPFLGLDSL
                     GGLIFAYLGNIAYNMYLIKGFYDTIPSSLEEAAMIDGATRFQTFYKIVVPLALPILTVI
                     VILTFIGTFNEFVLARIILQDVKNYTYALGLWTFSTGAYETEWGLFTAAALLGMTPMVI
                     LFLSLQKYIVGGLTKGSVKG"
     gene            7380..8801
                     /locus_tag="THEMA_05025"
     CDS             7380..8801
                     /locus_tag="THEMA_05025"
                     /inference="EXISTENCE: similar to AA
                     sequence:RefSeq:NP_229632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH13_20|CBM34|GH13"
                     /protein_id="AHD18274.1"
                     /translation="MMYPMPSWVYDSVVYQIFPDRFFIGKGKTVEDKKDLYLKRGGVIE
                     KWGVPPRKLPGAQHVKIFYGGDLWGIAEKVDYFEELGINVLYLTPIFLSDTNHKYDTID
                     YFRVDPQFGGKRAFLHLLRVLHERSMKLILDGVFNHVGSQHPWFKKAKKNDPEYVNRFF
                     LYKDRHRSWFDVGSLPELNVEVEEVKEYILKVVEHYLKLGIDGWRLDCGHDLGPTVNLW
                     INMKVKEFSAEKYLVSEIWTYPAGWDMVDGLMNYNFRNLVLSYVNGETDSIGFHLERAY
                     RETKNIFGCWNMLDSHDTPRLATMVPDRDLRKLAVVLQFTYPGVPLVYYGTEIGLTGGE
                     DPECRATMEWNREKWDVDLFEFYKKMIRLRRTDPGLRFGEFVLLNDSPLAFLRKAPHPL
                     QNTIVVVNPGEEKVLVLSIPDGKIMNTTPLVDVFSGERFHVDGGVVKLPLLARSFRILK
                     PEDLRVGKYRLYKRV"
     gene            8936..10378
                     /locus_tag="THEMA_05030"
     CDS             8936..10378
                     /locus_tag="THEMA_05030"
                     /inference="EXISTENCE: similar to AA
                     sequence:SwissProt:O33830.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH4"
                     /protein_id="AHD18275.1"
                     /translation="MPSVKIGIIGAGSAVFSLRLVSDLCKTPGLSGSTVTLMDIDEERL
                     DAILTIAKKYVEEVGADLKFEKTMNLDDVIIDADFVINTAMVGGHTYLEKVRQIGEKYG
                     YYRGIDAQEFNMVSDYYTFSNYNQLKYFVDIARKIEKLSPKAWYLQAANPIFEGTTLVT
                     RTVPIKAVGFCHGHYGVMEIVEKLGLEEEKVDWQVAGVNHGIWLNRFRYNGGNAYPLLD
                     KWIEEKSKDWKPENPFNDQLSPAAIDMYRFYGVMPIGDTVRNSSWRYHRDLETKKKWYG
                     EPWGGADSEIGWKWYQDTLGKVTEITKKVAKFIKENPSVRLSDLGSVLGKDLSEKQFVL
                     EVEKILDPERKSGEQHIPFIDALLNDNKARFVVNIPNKGIIHGIDDDVVVEVPALVDKN
                     GIHPEKIEPPLPDRVVKYYLRPRIMRMEMALEAFLTGDIRIIKELLYRDPRTKSDEQVE
                     KVIEEILALPENEEMRKHYLKR"
ORIGIN
        1 tcactttttg aaaatgtacg ctttcatggg atccacagtg aaggattcac ccgctgaaaa
       61 agacacgttt gactcgttcc agatgaagtt ttcaaaatct acctcgagaa tcatcgtcat
      121 gttttcttca aaagtgaagc tgttttgcca gactggatcc ggattcaaga ccaccaacag
      181 cttttcgttg gaggattctc tgtagaacgc tatgaggttt ttccagtccc tgaagatcgt
      241 ttgatctcca ttcaaaatgg cgtcgtgatc ttttctgaag ttgagaatga atctgatgaa
      301 attcaaaaga ctcttcggat cgctttcctg ttcttcgaca gaaaagccat cgtaaggatc
      361 gtcatagata catccgtcaa catcagcgtt tccaaaggtt atccccgcgt ttttgtagac
      421 ttcctttgtc cagaaggttt gaccttctcc tgtaccgctt gcgtaccact gcatcggctc
      481 tctcaccggc tcgtcatata caggaccgtg ccacttgaaa cctctcgttc caatttcacc
      541 gccgtagtag ataacaggag atcctttcag tgtgaatatc agaaaatacc agagagcagc
      601 acgttttttg atgaactcgt agtcggactc ggagaacttt ttgtaatgtt cttgaagatg
      661 ggagaagaac ctgtggagat cgtgattctc aagaaacagg aaagactcct caacccagtt
      721 gttttctatc attccatcct gcccttctgg gtagttcctt atactgtaca tgagggcgaa
      781 attgaaaacg ggaattggat atagagaaag atcgtacgtg tttccgctga acacctctcc
      841 cacaagtatg gcatcgggct ttttggaaag cacataatct ctgaaccatt caaaatattc
      901 ggccgactcc tgtatcccat cgtcccagga ccagccatat atgtgctttg cagcatctat
      961 tctgaatcca tcaacacctt tggaaatcca gaaatccacg attttcttta cttcttctct
     1021 cactttctga ctgtcgtggt tcagatccgg catgttatag ccaaaaagtc cgaaatacca
     1081 gactttttga ccctttgagt tgatcttcca gtgccagtga tcctgaccag aatgatcttc
     1141 aagactcatt atgtagtagt cccagtacgg agagctggtc gtgttttcca cggcgtcttt
     1201 gaaccaggga tgctcatcgg atgtgtggtt gatcacgaga tccattatta cctttattcc
     1261 gttctcatgg agcacctgga tcatgttttc gagatcttcc atggtgccgt agtctttctc
     1321 gacgttgtag tagtctgtta tgtcgtatcc atggtatgaa acagcctcgt tgaagggcat
     1381 aaaccacaca gcgtcaacgc cgagttcctt cagataatca actttctgag aaacaccgtt
     1441 taaatctccc actccgttcc cgtctctgtc gtaaaaagag cgaatgaaaa tttcgtagac
     1501 gacggggtat tttacttctt caaggttgga gctagtacca tctgtgtttg tgctgtttga
     1561 atgtggatta cttgaaacga gggattgact catagacgtt tgaaagcagg aggtgaggaa
     1621 gagtaaaaac acaaaagcaa gcagtaaaaa aggcttcttc acaaccttca ctcctcattt
     1681 tcgaaacatt ccacgatcaa taaattaaca caaatccgtc tgtttatatt aacacccaat
     1741 tcataacatg tcgatagggt taacggaatt tcgatatttc tgaatgaaac agttgatgag
     1801 taatttaaaa acaccgattc gaatccagat tgacatcacg aaaattcggt gttaaaatcc
     1861 ttagtgaaac attgtaatct aaaggaggtg tccatggtga agagactgct cgttttaatg
     1921 cttgttgtgg tttctgctct ggtgttatca caaacaaagc tcaccatctg gtgttccgaa
     1981 aagcaggttg acatcctcca gaaactcggg gaagaattca aggcaaagta cggaatccct
     2041 gttgaagttc agtacgtcga ttttggaagc atcaaatcca aattcctgac ggcggctcca
     2101 cagggacagg gcgcagacat cattgttgga gcgcacgact gggtaggaga actcgccgtc
     2161 aacggtttga tcgaacccat tcccaacttc tctgatctga agaatttcta tgacacggct
     2221 ctcaaagctt tctcttacgg tggaaaactc tacggagtcc cgtacgccat ggaagcggtt
     2281 gctctcatct acaacaagga ctacgttgat tctgttccta agaccatgga cgagctcata
     2341 gaaaaagcaa aacagataga tgaggaatac ggaggagaag tcagaggttt catctacgat
     2401 gtcgccaact tctacttctc tgcgccgttc attctaggtt acggaggata cgtcttcaag
     2461 gaaacacctc agggactcga cgtgacagac attggactcg cgaacgaagg agcagtcaaa
     2521 ggtgcgaaac tcataaagag aatgatcgat gaaggtgttc tcacccctgg tgacaactac
     2581 ggaacgatgg attccatgtt caaagaaggt ctcgcggcta tgatcatcaa cggactttgg
     2641 gctataaaat cctacaaaga tgcaggtata aactacggag tcgctcctat tcctgagctc
     2701 gagccgggtg ttcctgccaa accgtttgtt ggtgttcagg gattcatgat caatgccaag
     2761 tctccaaaca aagtgatcgc tatggaattt ctcacgaact tcattgcgag aaaagaaacc
     2821 atgtacaaga tatacctcgc agatccaagg cttcctgcga gaaaagatgt tcttgaactc
     2881 gtcaaagaca atcccgatgt tgttgcgttc acccagagtg cttccatggg aacaccgatg
     2941 ccaaacgtgc cggaaatggc tcctgtctgg tctgccatgg gagacgctct cagcatcatt
     3001 atcaacggac aggccagtgt cgaagatgct ctcaaagagg ctgtggaaaa aatcaaggca
     3061 cagatagaaa aataattcga agtgctatca ttagtcaaag aagaggggga cttttccccc
     3121 tcttttaaaa attcagggag gtctgatcgc tgtgaaaggg cttctcaaaa tctttctgat
     3181 attgtttctt gccgtattca acgcaggaat ggtctgggca ggaattttcc tgcttcaaaa
     3241 ttcttattat gaacttggaa tcgttcttct cacgcttctc gtactcatag attacttcat
     3301 cttcaacccg aaggcttatc cttacagata caccattccc gctttgatat tactttttgt
     3361 gctcgttctc tatcccatat acttcacggt gaaagttgcg ttcaccaatt atggaacagg
     3421 acacctcatg acgaaacaag aggccatcga gagaattctt ttcgacccga attacactta
     3481 tgttccagag agcgctgaac ctgttgaata catggttttc tccgtgttca acggtttgaa
     3541 tcctaccgag gattttgttg ttctcttcga gaaagatggg aacatctaca ttgcggagcg
     3601 ccccgttgtc acaaagagga gtgggaaaga ggtccttttg agagagtcaa ctctctttcc
     3661 cgtgaaggat ggaaccgccg aagtgaatgg gaaggtttat gagatagtcc cctggcccgc
     3721 ttccataaaa gaggtgaacg ccgtctattc agacggtaaa atttacaaac cgctttactc
     3781 acctgaagag gtttccctga agaggtacga acctttcttc aaggtaaatg tggttcagaa
     3841 gtatctcaac agggcagagt tttggctcga ggatcagagt tacatgttca gaataggtga
     3901 aaacggtgag tggaactttt atccagtgaa gaggctttat tctctgtctt tcgaagaatc
     3961 cctcgaaaac ggaaggataa caacgaaact tgtggtgaaa aacaatctca ctggaaggca
     4021 tctcgttgaa agggaaggtg ctttctacga ttacgacgaa aatggaagag aatttttcgt
     4081 gattggatac atggaataca ttggtttcaa gaacttctcc aggatattca ccgatccgaa
     4141 gatcgctggt ccttttttca aggttttcac ctggacgttc acctgggcag ccctcagcgt
     4201 tcttttaacg ttcgcgatag gtctttccct cgctcttgtt ctgaacgata aaacactgaa
     4261 gggaaagaac gtgtacagga cgttactcat tattccatgg gctgtgccag ctttcatttc
     4321 cgttctcgtc tggagaaacg ggatgttcaa cgagacttat ggaattctca accgatttgt
     4381 tcttccgttc ttgggattgg atccggtgaa gtggttcaac gatccgttct gggcgaaggt
     4441 cgcagttctc accgtcaaca cgtggctggg atttccgtac atgatggccg tctcactcgg
     4501 agctttgcag agcattccag aggagctcta cgaagccgct gcgatcgatg gagctggaag
     4561 gtggagaagg ttctggacta tcacgtttcc gcttctgatg accactgtgg ctcctctgtt
     4621 ggtcggaagt ttcgctttca acttcaacaa ctttgtgaac atatatctgc tcaccggtgg
     4681 aggtcccgca atggctggaa ccacaactcc tgttggacac acggacattt tgatctccta
     4741 cgtttacaaa ctcgcgttcg aaggaggaag aggacaggac ttcggttttg ccagtgccat
     4801 atccatcatc atattcttcc tcgttggagg aatcagcttt gtgaacttca aactctctgg
     4861 tgcgtttgaa gaggtgagtg aatgatggtg agaaaaaaga atagatggct cacgcatgtt
     4921 cttctaacac ttcttgttgt tgtggttctc ttccccatcg tttgggttgt ttctacctct
     4981 tttaggaggg atgaggcggc tttctccccg aaactcttct cgtctcgtct cacccttcag
     5041 cactacaaag atctggtggc acctgagaaa aaccttcccg ttctcataca ggagatgcag
     5101 agccttgttt ccagggttga accttttgat aacgtttcca gagagaaagc agaccgtctc
     5161 atcgaagatc gaatcagaag atttgaaaat tacctcgctg aaacgaagaa gcttttggag
     5221 gacgtcaacg cgagaaattc gaaaatagaa gagacgcttt cccagaggtt ctccgatgtg
     5281 ttgtcttaca caaaagatgt tctggaagag gcaaagaaat tgactcagga gcagatggat
     5341 aaaaccccat tgcccgattc acagaggatc gctgttgcac tctatgaaaa attgaaaggg
     5401 aaaaacttta gaagtgctga atttcaggct ttgaaggacg tgatcgagaa agtagtgggt
     5461 tacagcgttg agaatcagga cactctgaac gatgcccttt ctgaacttgg actggtttat
     5521 gagaaagaag taggaacgct catgaaagaa attgaaaaac tcgaaggtga aattgaaatc
     5581 cttcagagag aaatagccgt ccttgagaag cagaaggaaa cccttgaaaa agaaatcttg
     5641 gaaaaacaaa aagtactcga ggttttgaag cctgatatcg attccgtgag cgaagttctc
     5701 gtcaaactca aggaaatggt gcacagtgtc agaaacagta aagtggaaac tgctttccct
     5761 tatgaagact caagattgaa atcttcactc gaaaaacttc tgtctgaact caacactctc
     5821 tacgacaaga tctctgcttt ttctgatctt tcggatctct cagaaaagat atttgccatg
     5881 aagagttctt tagaagagat aaacaatgtg gtaagcgaag atggtgacat ttccaaaaaa
     5941 gccctctatg gaagctttgt tcaatccttt gaagagacgg ttcctattat tgaaggaatt
     6001 gtagagaaag tgagcgacgg aatcgacgat ttcgttcaga agataaagga tttgaaagat
     6061 atagaaaacg aaatcatggt actaacagca aaactcgatg gcctagagaa aagcttgaac
     6121 aatgtgagat cctccctctc tgagaaagag aaagaaattt cttcggcgaa gatgtatctg
     6181 gatctcaaga tcttcaacca tcagatccag agcagaatcg attctcttga aagcatgaaa
     6241 tctttcaaca acgccgcgca gataaagctt ctttcgatat acaagactct caagaacttt
     6301 gtgagtagct atgtgtcgga atacggagga gacgatttca tcggaaagat aagaaaactg
     6361 gcagcgaagc tctcctggat agaagactac agagatctga acagaaggat agaaacgggt
     6421 tacaaaaacg ctgtggaaat cgttgaaaaa gctcagaata tcctcgatga cttcaaggga
     6481 agttattcga atcttctcga tctttccttc aaaggacttt acgtttcctc tgagcacctt
     6541 gaaatgctgt acgaccttgt gaagatgaac ttcgttcaag aagttctcac gaacacagca
     6601 gtggcttcga gaaaggcagg aactctgatg gacaccattc ctttgaagga attgaagtcc
     6661 gatctcaaaa agatcgatgg agatctctac aggctcgcac agatatggga gcagaagaca
     6721 aagcattact tcctcagatg ggtcatgaac tcggtgatcg ttgcaggcct tgtttcactc
     6781 atcaccacgg ctgtttgtgc cctggcggcc tatccgttca gcagaatgag attctgggga
     6841 aggcagtacg gaatcatggc tcttcttctc attcagatgt tcccagccat catgtacatg
     6901 gttgcaatat acggtctttt gaagctcatc ggtcagttcc ttccattctt gggactggat
     6961 tctctcggag gcttgatatt cgcttatctc ggtaacatag cttacaacat gtacctcata
     7021 aagggattct acgacaccat tccttcgtct ctcgaagagg ccgctatgat cgacggtgca
     7081 accagattcc agaccttcta caagatagtc gttccactcg ctcttccgat cctcacggtc
     7141 atagtgatac tcaccttcat cgggacgttc aacgagttcg tccttgcaag gatcattctt
     7201 caggacgtga aaaactacac ttacgctctc ggcctctgga cgttctcaac gggtgcttat
     7261 gaaacagagt ggggcctttt cacggctgcc gctctcctcg gtatgacacc gatggtgata
     7321 ctcttcctgt ccctccagaa gtacatagtg ggtggactca cgaaaggatc ggtgaaagga
     7381 tgatgtaccc gatgccgtct tgggtttacg acagtgtcgt gtatcagatc tttccagata
     7441 gatttttcat cggaaaggga aaaacggtgg aagacaaaaa ggatctgtac ctgaagcggg
     7501 gaggagtcat agagaaatgg ggagttcctc cccgcaaact tcccggtgct cagcacgtga
     7561 agatcttcta cggaggagat ctgtggggaa tagccgagaa ggtcgattat tttgaagaac
     7621 ttggaatcaa cgttctgtac ctcactccta tctttttgtc cgataccaat cacaagtacg
     7681 acacgatcga ttacttcagg gtggatccac agttcggcgg aaagagggct tttctgcacc
     7741 ttttgagggt tctccatgag aggagtatga aactcattct cgatggtgtg ttcaaccacg
     7801 ttgggagtca gcatccgtgg ttcaaaaaag cgaagaaaaa cgatccagag tacgtgaaca
     7861 gatttttcct ttacaaagat aggcacagat cgtggttcga cgttggaagc cttcccgagc
     7921 tgaacgtgga agtcgaagaa gtgaaggaat acattttgaa agttgtcgag cactacctga
     7981 aactggggat agacggttgg aggctggatt gtggccacga tcttggacct accgtcaacc
     8041 tgtggatcaa catgaaagtg aaagagttct cagcggaaaa gtacctcgtg agtgagatat
     8101 ggacttaccc ggcaggatgg gatatggttg atggtctgat gaattacaac ttcagaaacc
     8161 ttgtgcttag ttatgtgaac ggcgagacgg attccatagg ttttcacctg gaaagagctt
     8221 acagggagac gaagaacata ttcggttgct ggaacatgct tgacagtcac gacaccccga
     8281 gactcgccac aatggttccc gacagagacc tgagaaaact cgctgtagtt cttcagttca
     8341 cttatcccgg tgttccgctc gtttactatg gaacagagat aggtctcaca ggtggagaag
     8401 atccagagtg tcgtgccacc atggaatgga acagagagaa atgggatgtt gatctgttcg
     8461 agttctacaa gaagatgatc agactgagaa ggacggatcc aggtttgcgc tttggagagt
     8521 ttgtcttgct gaacgactca cctctcgcgt ttctcagaaa ggctcctcat cctcttcaaa
     8581 acaccatcgt ggtggtgaac ccaggagaag agaaggtgct ggttctctcc attcccgacg
     8641 ggaaaattat gaacaccact ccccttgtcg atgtgttcag cggagaaaga ttccacgttg
     8701 acggcggggt tgtgaagctt ccccttctag cgagatcttt cagaattctc aagcccgagg
     8761 atctgagagt gggtaagtac agattgtaca agagagtttg aaaaaattca ttgaagattc
     8821 cggctggctt ccggccagcc ttttaatttt ttaagaagcg tttgaattca tggaaaaaac
     8881 gttcggaaag tatatagttg taactggtgg atacgaaata cagggaggtg tttttatgcc
     8941 atctgtgaag atcggtatca tcggtgcggg gagcgcggtg ttttctctga ggcttgtgag
     9001 tgatctttgc aaaacgccgg gactctctgg cagcacggtc accctcatgg atatcgacga
     9061 agaaagactc gacgctattc tgaccatcgc gaaaaaatac gttgaagaag tgggagcgga
     9121 tctgaaattc gaaaaaacca tgaatttaga tgacgtcatc atcgacgcgg attttgtgat
     9181 aaacacagcg atggtgggtg gccataccta cttggagaag gtcagacaga tcggtgagaa
     9241 atacggctac tacagaggaa tagacgctca ggagtttaac atggtctccg actactacac
     9301 cttctccaac tacaaccagc tcaagtactt cgttgacata gcaaggaaga tagagaagct
     9361 ctccccaaaa gcctggtact tgcaggcagc gaaccccatt ttcgagggaa caacccttgt
     9421 gacaagaacg gttcccataa aggcagtggg attctgccat ggacactacg gcgtgatgga
     9481 gatcgtagag aaactggggc tggaagaaga aaaagtagat tggcaggtcg caggagtgaa
     9541 ccacggtatc tggctgaata ggttcagata caacgggggg aacgcgtatc ccctccttga
     9601 caagtggatc gaggaaaaat caaaagattg gaaaccagag aaccccttca acgaccagct
     9661 ctctcccgcc gcgatagaca tgtacagatt ctacggtgtg atgcccatcg gtgacaccgt
     9721 gagaaactct tcgtggaggt accacaggga tcttgaaacc aagaagaagt ggtacggtga
     9781 accctgggga ggagcagatt ctgaaatagg ctggaaatgg taccaagaca cgcttggaaa
     9841 ggtcacggag atcacaaaga aggtggcaaa gttcatcaaa gaaaatccgt ccgtgaggct
     9901 ctccgacctt ggaagtgttc tggggaaaga cctctcagaa aagcagtttg tgctcgaagt
     9961 ggagaaaatt ctcgatccag aaagaaagag tggagagcag cacatcccat tcatcgatgc
    10021 gctgctgaac gataacaagg caagattcgt ggtgaacata ccaaataaag gtatcattca
    10081 cggaatagac gatgacgtgg ttgttgaagt cccagccctt gtggacaaga acggaatcca
    10141 tcccgagaag atcgaaccac cgcttccaga tcgcgtggtc aagtactacc tgagacccag
    10201 aatcatgagg atggaaatgg ctctggaggc gtttctaacg ggtgacataa ggatcataaa
    10261 agaacttctc tacagagatc caaggacaaa gagcgatgaa caggtagaaa aggtgatcga
    10321 ggagatcctc gcacttccag aaaacgaaga gatgcggaaa cattatctga agagatga
//
