LOCUS       NC_014033              12836 bp    DNA     linear   CON 25-AUG-2019
DEFINITION  Prevotella ruminicola 23, complete genome.
ACCESSION   NC_014033
VERSION     NC_014033.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN02604020
            Assembly: GCF_000025925.1
KEYWORDS    RefSeq.
SOURCE      Prevotella ruminicola 23
  ORGANISM  Prevotella ruminicola 23
            Bacteria; Bacteroidetes; Bacteroidia; Bacteroidales; Prevotellaceae;
            Prevotella.
REFERENCE   1  (bases 1 to 12836)
  AUTHORS   Purushe,J., Fouts,D.E., Morrison,M., White,B.A., Mackie,R.I.,
            Coutinho,P.M., Henrissat,B. and Nelson,K.E.
  CONSRTM   North American Consortium for Rumen Bacteria
  TITLE     Comparative genome analysis of Prevotella ruminicola and Prevotella
            bryantii: insights into their environmental niche
  JOURNAL   Microb. Ecol. 60 (4), 721-729 (2010)
   PUBMED   20585943
REFERENCE   2  (bases 1 to 12836)
  AUTHORS   Brinkac,L., Coutinho,P.M., Daugherty,S., Dodson,B., Durkin,A.S.,
            Fouts,D.E., Henrissat,B., Mackie,R.I., Madupu,R., Morrison,M.,
            Nelson,K.E., Purushe,J., Rosovitz,M.J., Sullivan,S., Torralba,M. and
            White,B.A.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-APR-2010) The J. Craig Venter Institute, 9704 Medical
            Center Dr., Rockville, MD 20850, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 08/25/2019 21:09:10
            Annotation Pipeline               :: NCBI Prokaryotic Genome
            Annotation Method                 :: Best-placed reference protein
            Annotation Software revision      :: 4.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
            Genes (total)                     :: 3,006
            CDSs (total)                      :: 2,938
            Genes (coding)                    :: 2,891
            CDSs (with protein)               :: 2,891
            Genes (RNA)                       :: 68
            rRNAs                             :: 4, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 47
            CDSs (without protein)            :: 47
            Pseudo Genes (ambiguous residues) :: 0 of 47
            Pseudo Genes (frameshifted)       :: 6 of 47
            Pseudo Genes (incomplete)         :: 37 of 47
            Pseudo Genes (internal stop)      :: 6 of 47
            Pseudo Genes (multiple problems)  :: 2 of 47
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence was derived from
            CP002006.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            DNA and bacteria available from Mark Morrison, Queensland
            Bioscience Precinct, CSIRO Australia, 306 Carmody Road, St. Lucia,
            Queensland, 4067, Australia.
            Annotation Pipeline (PGAP)
            set; GeneMarkS-2+
            repeat_region
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..12836
                     /organism="Prevotella ruminicola 23"
                     /mol_type="genomic DNA"
                     /strain="Bryant 23"
                     /type_material="type strain of Prevotella ruminicola"
                     /db_xref="taxon:264731"
                     /note="type strain of Prevotella ruminicola"
     gene            1..2181
                     /locus_tag="PRU_RS13995"
                     /old_locus_tag="PRU_2728"
                     /db_xref="GeneID:31502259"
     CDS             1..2181
                     /locus_tag="PRU_RS13995"
                     /old_locus_tag="PRU_2728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004290689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH10|CE1|CBM22"
                     /protein_id="WP_013065621.1"
                     /db_xref="GeneID:31502259"
                     /translation="MKKLLVALSLIAGSLTASAQWGRPVDYAAGPGLKDAYKDYFTVGV
                     AVNKFNISDPAQTAIVKKQFNSVTAENAWKPGEIHPKEGVWNFGLADSIANFCRENGIK
                     MRGHCLCWHSQFADWMFTDKKGKPVKKEVFYQRLREHIHTVVNRYKDVVYAWDVVNEAM
                     ADDGRPFEFVDGKMVPASPYRQSRHFKLCGDEFIAKAFEFAREADPTGVLMYNDYSCVD
                     EGKRERIYNMVKKMKEAGVPIDGIGMQGHYNIYFPDEEKLEKAINRFSEIVNTIHITEL
                     DLRTNTESGGQLMFSRGEAKPQPGYMQTLQEDQYARLFKIFRKHKDVIKNVTFWNLSDK
                     DSWLGVNNHPLPFDENFKAKRSLQIIRDFDAAMDNRKPKEDFVPNPMNQPGQEYPMVNS
                     EGYARFRVEAPDAKSVIVSLGLGGRGGTVLRKDKNGVWTGTTEGPMDPGFHYYHLTIDG
                     GVFNDPGTHNYFGSCRWESGIEIPAKDQDFYAYRKDINHGNIQQVTFWSESTGKMQTAN
                     VYLPYGYGKVVKGKQERYPVLYLQHGWGENETSWPVQGKAGLIMDNLIADGKIKPFIVV
                     MAYGLTNDFKFGSIGKFTAEEFEKVLIDELIPTIDKNFLTKADKWNRAMAGLSMGGMET
                     KLITLRRPEMFGYWGLLSGGTYMPEEIKDPKAVKYIFVGCGDKENPEGINKSVEALKAA
                     GFKAEGLVSEGTAHEFLTWRRCLEKMAQSLFK"
     gene            2450..4915
                     /locus_tag="PRU_RS14000"
                     /old_locus_tag="PRU_2729"
                     /db_xref="GeneID:31502260"
     CDS             2450..4915
                     /locus_tag="PRU_RS14000"
                     /old_locus_tag="PRU_2729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008620441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH95"
                     /protein_id="WP_013064566.1"
                     /db_xref="GeneID:31502260"
                     /translation="MKRLLTILASVCVALVVNAQQHKLWYSKPAAQWLEALPIGNSHLG
                     AMVYGGIGTEQIQLNEETFWSGSPHNNNNPDAKVAMKDVRRLIFEGKEKEAEALIDKTF
                     FKGPHGQKYLPLGDLMLSFDYQNGAEPSNYRRELNLGDALCTTSFDVADVKYIRTAFAS
                     QADNAIIIQLTASKKKALNFGVSYQRNQQAVEGGAVAKNEHAYIINNVEHEGIAGKLQA
                     EVRVKVVADGTVTDMGSDMQVRNATNATIFITAATNYVNYQTINGDPVAKNNLTMQLLK
                     GKNYKQLLKRHLDKYQDQYDRVSLSLAKSAQSELPTDERLAAFDGTDLDMVSLMMQYGR
                     YLLISSSQPGGQPANLQGVWNHKMDPAWDSKYTININAEMNYWPANVGNLAETQEPLFS
                     MIRDLSVTGAKTARTMYNCPGWVAHHNTDLWRIAGPVDGTSWGMFPTGGAWLTTHLWQY
                     YLYTGDKRFLDACYPILKGASDFLLSYMQEYPKNGEVKQAAGWLVTVPTVSPEHGPVGK
                     NTTVTAGSTMDNQIVFDVLSSTLRAHQILGYNNVVYTTMLSNAIAKLPPMQIGRYGQLQ
                     EWLIDGDDPKDEHRHISHLYGLYPSNQISPYSHPDLFTAASNTLNQRGDMATGWSLGWK
                     INFWARMQDGNHAFKIIKNMLNVIPSTTEWGRSGGTYPNLFDAHPPFQIDGNFGCSAGV
                     CEMLLQSHDGAVHLLPALPDSWKDGEVSGLVARGAFTVSMKWHQGELTEATIYSKIGGQ
                     LRLRSYVPLQGAGLKPAQGECSNELLAPAAIREPLVSEELKDFKTLPIRKVYEYDIMTA
                     PGKTYYIKH"
     gene            4946..7531
                     /locus_tag="PRU_RS14005"
                     /old_locus_tag="PRU_2730"
                     /db_xref="GeneID:31502261"
     CDS             4946..7531
                     /locus_tag="PRU_RS14005"
                     /old_locus_tag="PRU_2730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007211516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH3"
                     /protein_id="WP_013064096.1"
                     /db_xref="GeneID:31502261"
                     /translation="MKYQLFLSLALCVGLGASAQTLPYQNPNLSAKERAVDLCSRLTLE
                     EKAMLMLDESPAIPRLGIKKFFWWSEALHGAANMGNVTNFPEPVGMAASFNPHLLFKVF
                     DIASTEFRAQYNHRMYDLNGEDMKMRSLSVWTPNVNIFRDPRWGRGQETYGEDPYLTSV
                     MGVQVVKGLQGPEDARYRKLWACAKHYAVHSGPEYTRHTANLTDVSARDFWETYMPAFK
                     TLVKDAKVREVMCAYQRLDDDPCCGSTRLLQQILRDEWGFEYLVVSDCGAVSDFYENHK
                     SSSDAVHGTSKAVLAGTDVECGFNYAYKSLPEAVRKGLLSEKEVDKHVIRLLEGRFDLG
                     EMDDPSLVEWSKIPYSAMSTKASANVALDMARQTIVLLQNKNNILPLKKNAEKIAIIGP
                     NAHNEPMMWGNYNGTPNHTVTILDGVKAKQKKLVYIPGCDLTNDKVMECHLATDCVTPD
                     GKKGLKGTFWNNTEMAGKPFTTEYYTKPVNVTTAGMHVFAPNLPIEDFSAKYETTFTAK
                     EAGEYVVNVESTGHFELYVNGKQQFVNHIWRATPTRTVLKAEKGQKFDIEVRFQTVKTW
                     GASMKIDVARELNIDYQETIAQLKGINKVIFCGGIAPSLEGEEMPVNIEGFKGGDRTSI
                     ELPKVQREFLKALKAAGKQVIYVNCSGSAIALQPETESCDAIVQAWYPGQEGGTAVADV
                     LFGDYNPGGKLSVTFYKNDQQLPDYEDYSMKGRTYRYFDDALFPFGYGLSYTTFEVGEA
                     KVEAATDGALYNVQIPVTNTGTKNGSETIQLYIRNLQDPDGPLKSLRGFERLDIKAGKT
                     ATANLKLTKESLEFWDAETNTMRTKPGKYEILYGTSSLDKDLKKLTITL"
     gene            complement(7521..8927)
                     /locus_tag="PRU_RS14010"
                     /old_locus_tag="PRU_2731"
                     /db_xref="GeneID:31502262"
     CDS             complement(7521..8927)
                     /locus_tag="PRU_RS14010"
                     /old_locus_tag="PRU_2731"
                     /inference="COORDINATES: protein motif:HMM:PF13416.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="STP|SBP_bac_1"
                     /protein_id="WP_080517213.1"
                     /db_xref="GeneID:31502262"
                     /translation="MWICKLSLVLYRIQEILRYVATRLYEGARRALNKKRNDMKRLATA
                     ILALCCSLAIQAQDRQQILKVYNWGDYIGVGVIEKFEKWYQQVTGQPIKVSYVTYDYPE
                     ECFDMIKDQQTEVDVFCPPEYLAERMMKHKMLTPIDTSFVAQGIPNYLHGTSPFIDNML
                     QHIGEAQGITAKDYTVGYLWGNTGVLINTKFVKPEEVNSWAFLFDSKYRGKVIMKDSFS
                     DIYNVFINYAFYDDIKSGVANRNLLAAYLTNRNIAIVEDLLESARPQMKSFDVEDDKRL
                     MSAGKDWMSITWNGDARWAIDEAGDNTNLQYVVPIEGSDCWADCWVIPTTCKNIKAASL
                     WINFLCRPDIALLCMEETGYSSAIGTPEILQAVTNDSLPAIDLSYFFGPEATAVHVDSV
                     MYPTKDVISRCSYLRDSGDRQEVLREIWEKIKEKPVVDYWFYVIAGCVALFMIITTTLL
                     LRQKKTTTIK"
     gene            complement(8831..12835)
                     /locus_tag="PRU_RS14015"
                     /old_locus_tag="PRU_2732"
                     /db_xref="GeneID:31502263"
     CDS             complement(8831..12835)
                     /locus_tag="PRU_RS14015"
                     /old_locus_tag="PRU_2732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019969053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DBD-Pfam|HTH_AraC,DBD-Pfam|HTH_AraC,DBD-SUPERFAMI
                     LY|0036286,DBD-SUPERFAMILY|0035607"
                     /protein_id="WP_013064354.1"
                     /db_xref="GeneID:31502263"
                     /translation="MKVKYILTLATSLLSLSAFAQRGKFFTTDHQLSSSFVTQVYLDNE
                     GFIWTTTRNGINRYDGYQFRVFKKENEHDSSLASNYVNSMMQDRNGLFYFGMYGALQTW
                     DGTKFHNVTMYDKNGNAGHSYPNCFLERANGDVLVGTSGLGILKFKDQKTAYQEKGPLA
                     TIHTVNSMIEDRTGTLWIVTEHMGLISYNGKTVKRHMQNLPSVVFSCLCEGADGIIYAG
                     STNCGVFRMQGDTFVHIAETGTKAVSSLYCAHDGNIVIGYDGQGIALYNPRKPELIDNP
                     FFSLEVNLPMSKVYSITEDKSGNLWFGLLQKGIFMQPISFKGFHYMGHKLGAHNILGTA
                     CVISVILDSKKRVWVGTDKDGLYCYDFYSQASKHLKDQYPSVIVSLAEDQKGRIWLGTY
                     REGIGWVDPVTFQYHRVPFPMDPNLIVMDIAVGNDGYLWLGTMKHGIVKMDPNDGRVLA
                     IYKMKAGADKNRKMNCITNDYVSQVQLSPDGKRLYVSTSMGLCCLDIPANSWTSTFGMN
                     CLNYSTPVRITREYDGNLWYGTNEGLFRYDLRTHKTQQYTRADGLADNGIATIERDLQG
                     RLWIGTDHGLSCFTPKSDIWQNYFVDDGLQSNEFSDGASFMSPDGILTMGGTAGISWFD
                     SHHIAPSKWEAEVELTSFSINGQQVSRATHSGSYLVTDTTIIASNRFELSYSDNTFSIQ
                     FSTLTYENPEHISYLYSINGEPFNRLQPGENVLTLSHLPQGTYRFRVKAERNNVETPVR
                     EFTVVIHSPWYRSAWAYFFYAMVIGMFVWQYLVYRRHKEQDKLRLQAHIHAEEMGEAKL
                     RFFMNMSHEIRTPMTLILTPLLSLIKNDNDPSRKAVYETIRRNAERILSLINQMMDLRK
                     IDKGQMQMRMRETNLVSFAKDIYDLFDNQAKTKQIKFIYEHDSDKIPVWIDRQNFDKVL
                     MNVLSNAFKYTPTGGEIGIRISHTDESATIAIYDNGEGIPEDKMNKIFDRFYQTPTTLN
                     DRYVGTGIGLDLTRSLVELHHGTITVHNLEKGCEFVITIPMGNSHLNADEMITEAEAAE
                     AAETITPELLLEEEPETELINPMSEMTPGNRKLTLVIAEDDEEIRNYLESELSKDYDIH
                     ACTNGREALGEVIRTKPDLVLSDIMMPEMDGNTLCTRIKTNPNTNSIPVVLLTAKNRDE
                     DKLESLETGADAYIVKPFNMEILRRTIMNLINKHRLLRLKYERNDSLEEQIDEIELKSP
                     DEKLLERIMECINKNLNNSDLSVDMIADTVGISRVHLHRKMKDLTGQTPHDFIRNIRLK
                     KAAQLLANQGMNVTEVMYACGFANSASFSTVFKKFYGMSPRDYMKEHEER"
ORIGIN
        1 atgaagaaac tattagtagc gttatcgctt atcgccggta gcctgacagc atcggcacag
       61 tggggacgtc ctgtagatta tgcagcaggt cctggactta aggatgctta caaggattat
      121 tttactgtag gtgtggctgt aaacaagttc aacatctctg atcctgctca gactgcaatc
      181 gtaaagaagc agtttaacag cgttactgcc gagaatgctt ggaaaccagg cgagattcat
      241 cccaaagagg gtgtgtggaa ctttggcttg gccgacagca ttgccaactt ctgccgcgaa
      301 aacggtatca agatgcgtgg tcactgcttg tgctggcact cacagtttgc cgactggatg
      361 tttaccgata agaagggtaa gccagtaaag aaagaggtat tctaccagcg tttgcgcgag
      421 catatccaca ccgtggttaa ccgctataag gacgtggttt atgcttggga cgtagtaaac
      481 gaggctatgg ccgatgacgg tcgtccattc gagtttgttg atggtaagat ggtgcctgcc
      541 agcccttatc gtcagagccg tcattttaag ctttgtggcg atgagtttat tgctaaggct
      601 tttgagtttg cacgcgaggc cgacccaaca ggtgtgctga tgtacaacga ctacagctgt
      661 gttgacgagg gtaagcgcga gcgtatatat aatatggtga agaagatgaa ggaggctggt
      721 gtgcccatcg atggtatcgg catgcagggt cactataaca tctacttccc tgatgaggag
      781 aagctggaga aggccatcaa ccgtttcagc gagattgtaa acactatcca cattacagag
      841 ctggatctgc gtaccaatac cgagagcggt ggtcagctga tgttctcgcg tggcgaggct
      901 aaaccacagc ctggttatat gcagacactg caggaggacc agtatgcccg tttgttcaag
      961 atattccgta agcataagga tgtgattaag aacgttacat tctggaacct gagcgataag
     1021 gactcttggc tgggtgtaaa caatcaccca ctgcctttcg acgagaactt caaggctaag
     1081 cgctcgctgc agattatccg cgactttgat gccgctatgg acaatcgcaa gccaaaagag
     1141 gactttgtgc ccaaccccat gaaccagccc ggacaggagt atcctatggt taactctgag
     1201 ggttacgccc gcttccgtgt tgaggctccc gatgctaagt cggtaattgt aagcctgggt
     1261 cttggtggcc gtggcggtac cgtactgcgc aaggataaaa atggtgtttg gactggtact
     1321 accgagggcc caatggatcc tggtttccac tactatcacc tgactatcga tggtggcgtg
     1381 tttaacgatc ctggtacaca caactacttc ggttcttgcc gttgggagag tggtatcgag
     1441 attcctgcca aggatcagga cttctacgct tatcgcaagg atatcaacca tggtaacatc
     1501 cagcaggtaa ccttctggag cgagagcact ggtaagatgc agactgccaa tgtttatctg
     1561 ccttacggtt acggcaaggt ggtaaagggt aagcaggagc gctatcctgt actgtacctg
     1621 cagcacggtt ggggtgagaa cgaaaccagc tggcctgtac agggtaaggc tggactcatc
     1681 atggacaacc tgattgccga tggtaagatt aagccattta tcgtagtaat ggcctacgga
     1741 ctgactaacg actttaagtt cggttcaatc ggtaagttta ctgccgagga gtttgagaag
     1801 gtactcatcg acgaactgat tcctactatc gataagaact tcctgaccaa ggccgacaag
     1861 tggaaccgtg cgatggcagg tctgtcgatg ggtggtatgg aaaccaagct catcaccctg
     1921 cgccgtcctg agatgttcgg ttactgggga ttgctgagtg gtggcaccta tatgcccgag
     1981 gaaattaagg atcctaaggc tgtgaagtat atcttcgtag gttgtggcga caaggagaac
     2041 ccagagggca tcaacaagag cgttgaggca ctgaaggctg ctggatttaa ggccgaaggt
     2101 ctggtttctg agggcactgc acacgagttc ctgacatggc gtcgttgcct tgaaaagatg
     2161 gctcagagtc tctttaagta aggaaaagtg cgaaaaaagt gtgatttttt agtggttgaa
     2221 acaaaataaa aagtaaatgt aacatgagga taagccactt tcgaaaaaat acactaactt
     2281 tgcacccaga taaaataaag aatcggttaa aattgtttta gttatattag tagttagtag
     2341 tttttccttc cctgggacta aagaaaggcg tttcttgtcc cagggttatt ttttaaattc
     2401 ataaattatt tgtatctttg cagcgaaatt taaaaccaat agtatatata tgaaacgatt
     2461 attgactatc cttgccagtg tgtgtgtagc acttgtggtt aatgcccagc agcacaagct
     2521 gtggtacagt aagcctgccg ctcagtggtt agaagccctg cctataggca attcgcactt
     2581 aggtgccatg gtgtatggcg gtatcggtac agagcagata cagctgaacg aagaaacctt
     2641 ctggagcggc tcgccgcaca ataacaacaa tcctgatgcc aaggtggcta tgaaggatgt
     2701 gcgacgcctg atttttgaag gcaaagaaaa ggaagccgag gcgctgattg acaagacttt
     2761 ctttaaagga ccccatggac aaaagtatct gcccctgggc gacctgatgc tttctttcga
     2821 ctaccaaaat ggggctgaac caagcaatta tcgtcgcgaa ctgaatctgg gtgatgcttt
     2881 gtgtaccacc agttttgatg tggctgatgt gaaatatatt cgtacagcct ttgcctcgca
     2941 ggccgataac gccattatca tacagctgac tgccagcaag aagaaagccc tgaacttcgg
     3001 ggtgagctat cagcgcaacc agcaggctgt tgagggcggt gctgtggcca agaacgagca
     3061 tgcctatatt attaataatg tagagcacga gggtatcgct ggcaagctgc aggccgaggt
     3121 gcgtgtaaaa gtagtggccg atggaactgt gaccgatatg ggcagcgata tgcaggtgcg
     3181 aaatgctacc aatgccacta tctttattac ggcggctacc aactacgtga actatcagac
     3241 tattaacggc gatccggttg cgaaaaacaa cctgaccatg cagttgctga aaggcaagaa
     3301 ctacaagcaa ctgttgaaac gccatctgga taagtatcag gatcagtacg atcgtgtgtc
     3361 gctgtcgtta gccaaatcgg cgcagtcgga gctgcctacc gatgaacgtc tggcagcttt
     3421 cgatggtacc gatctggata tggtgtcgct gatgatgcag tacggacgat acctgctgat
     3481 atcatcgtcg cagcctggtg gtcagcctgc caacctgcag ggggtatgga accataagat
     3541 ggatcccgct tgggactcga aatataccat caacatcaat gccgagatga actactggcc
     3601 tgccaatgtg ggtaatctgg ctgagacaca ggagccactg ttctcgatga ttcgcgacct
     3661 gagtgtcaca ggcgctaaaa cggctcgtac catgtacaac tgtccgggtt gggtggcgca
     3721 tcataatacc gacctgtggc gtattgccgg tcctgtggat ggtaccagct ggggaatgtt
     3781 cccaacaggt ggtgcctggc ttaccacgca cctgtggcag tactacctgt atactggcga
     3841 caagcgattc cttgatgctt gctatcccat cctgaaagga gcttccgatt tcctgctgtc
     3901 gtatatgcag gaatatccaa agaacggcga agtgaagcag gctgccggct ggctggtaac
     3961 ggtgccaaca gtatcgcctg aacatggacc agtaggcaag aacaccaccg taacagctgg
     4021 atcaacaatg gacaaccaga tagtgtttga tgtgctgagc agtaccctga gggcacacca
     4081 gatactgggc tataataatg tggtttatac caccatgctg agcaatgcca ttgccaagct
     4141 accacctatg cagataggta gatacggaca gttgcaggag tggctgattg atggcgacga
     4201 tccaaaagat gagcatcgcc atatatcgca tctgtacggc ttgtatcctt cgaaccagat
     4261 atctccctac agtcatcccg atctgtttac cgctgcgtct aacaccctga accagcgcgg
     4321 cgatatggct actggctgga gtctgggttg gaagatcaac ttctgggcac gtatgcagga
     4381 tggcaaccat gcctttaaga ttatcaagaa catgctgaac gtgataccca gcaccacaga
     4441 gtgggggcgc agtggcggta cctatcccaa cttgtttgat gcccatccac cattccagat
     4501 tgatggtaac ttcggttgct cggctggcgt atgcgagatg ctgttgcaga gtcatgatgg
     4561 cgctgtacac ctgttgcccg ccctgcctga tagttggaaa gatggcgagg tgagtggact
     4621 ggtggccaga ggtgccttta cggtaagtat gaagtggcac cagggtgaac tgaccgaggc
     4681 tactatatac tcgaagattg gcggacagct gcgtctgcgt tcgtatgtgc cattgcaggg
     4741 ggctggtttg aagccggctc agggtgagtg cagtaacgag ctgttggcac ctgctgccat
     4801 ccgcgagcca ttggtgtcgg aagagctgaa ggactttaag acactgccca tccgcaaggt
     4861 gtacgagtat gatatcatga ccgcaccggg gaaaacgtat tacattaaac attaaacatt
     4921 aaagattaaa gattaaacat taaagatgaa atatcaacta ttcttatcat tggcattgtg
     4981 tgtggggctg ggagcctcgg cacaaacatt gccttaccag aacccgaacc tctcggctaa
     5041 agagcgagcc gttgaccttt gtagtagact gactttggaa gagaaagcca tgctgatgct
     5101 ggatgagagt ccggccatcc cccgcttggg catcaagaaa ttcttctggt ggagcgaggc
     5161 gctgcatggt gcggctaaca tgggtaacgt aaccaatttc cctgagcctg taggtatggc
     5221 tgcgtcgttc aaccctcatc tgctgtttaa ggtgttcgac atcgcatcta ccgagttccg
     5281 tgctcagtac aatcatcgta tgtacgacct gaatggcgag gatatgaaga tgcgtagcct
     5341 ctctgtttgg acaccaaacg tgaacatttt ccgcgaccct cgttggggac gtggacagga
     5401 aacctatggc gaggatccct atcttaccag tgtgatgggc gtgcaggtgg tgaaaggctt
     5461 gcaggggcct gaggatgcca gataccgtaa gctctgggcc tgtgccaagc actatgccgt
     5521 gcacagtggt cctgagtaca cacgtcatac tgccaacctg actgatgtgt cggcccgtga
     5581 cttctgggag acttatatgc ctgccttcaa gacattggta aaggatgcga aagtgcgcga
     5641 ggtgatgtgt gcctatcagc gtctggacga tgatccctgc tgtggttcaa cccgtctgct
     5701 ccagcagata ttgcgcgatg agtggggctt tgagtacctc gttgtgagcg actgtggtgc
     5761 tgttagcgac ttctacgaga accataagtc gtcgtcggat gccgtacatg gtacatcgaa
     5821 agctgtcttg gctggtaccg atgtagagtg tggctttaac tatgcctata agagtctgcc
     5881 cgaggcagtc agaaaaggtc tgctctctga gaaggaggtt gataagcacg tgatccgttt
     5941 gctcgaaggt cgtttcgacc tgggtgagat ggatgatccg tcgctggtgg agtggtcgaa
     6001 gattccttat tcggctatgt cgaccaaggc ttcggctaac gtagcgctgg acatggcccg
     6061 tcagaccatc gtactgcttc agaacaagaa caatatcctg cctctgaaga agaatgccga
     6121 gaagattgcc attatcggtc ctaatgctca taacgagcct atgatgtggg gaaactataa
     6181 tggtactcct aaccataccg ttaccatcct ggatggtgtg aaggctaagc agaagaaact
     6241 ggtttatata cctggctgcg acctgacaaa tgataaggtg atggagtgcc atctggctac
     6301 cgactgtgta actcccgatg gtaagaaagg cttgaagggt acattctgga acaacacaga
     6361 gatggctgga aagcccttta ctaccgaata ctacaccaaa ccggtaaatg taaccactgc
     6421 aggtatgcac gtgtttgcac ccaacctgcc tatcgaggat ttctcggcta agtacgagac
     6481 aacctttaca gccaaagagg ctggcgagta tgtggtaaac gtggagagta ctggtcattt
     6541 cgaactctat gtcaatggca agcagcagtt tgtgaaccat atctggcgtg caacaccaac
     6601 acgcacggtg ctgaaagctg aaaagggtca gaagtttgat attgaggtac gtttccagac
     6661 cgtgaagaca tggggtgctt cgatgaagat tgatgtggct cgcgagctga atatcgatta
     6721 tcaagagacc atcgcccagc tgaagggtat caataaggtg attttctgtg gtggtatcgc
     6781 tcccagtctg gagggcgagg agatgcctgt aaacatcgag ggctttaaag gtggcgaccg
     6841 taccagcatc gaactgccta aggtgcagcg cgagttcctg aaggccctga aggctgcagg
     6901 aaagcaggtg atctatgtaa actgttcggg ttcggctatt gccctgcagc cagagacaga
     6961 aagctgcgat gctatcgtac aggcctggta tcctggtcag gagggtggta cagctgtggc
     7021 cgacgtgctc tttggcgact ataacccagg cggaaaactg tcggtaacct tctataagaa
     7081 cgaccagcag ctgcccgatt atgaggacta ctcgatgaag ggtcgtacct atcgctattt
     7141 tgatgatgcg ctgttcccct tcggctatgg cttgagctat actactttcg aggtgggcga
     7201 ggctaaggtt gaggctgcta ccgatggtgc gctttacaac gtacagatac ctgtaaccaa
     7261 taccggcacc aagaacggta gcgaaaccat ccagctgtat atccgcaacc tgcaggatcc
     7321 cgacggtcca ctgaagagtc tgcgtggctt tgagcgtttg gatatcaagg ccggtaagac
     7381 ggcaacagcc aacctgaagc tgaccaagga gtcgttggag ttctgggatg ctgagacaaa
     7441 caccatgcga accaaacccg gaaagtacga gatactctac ggaaccagtt cgttggacaa
     7501 agatctgaaa aaactgacca tcactttata gtggtggtct ttttttgacg taacaaaagt
     7561 gtagtggtga taatcataaa cagggctaca cagcctgcaa tcacgtagaa ccagtaatca
     7621 acaacaggtt tctccttgat tttctcccaa atctcacgaa gcacttcctg gcggtcgcca
     7681 ctgtcgcgta gatagctgca acggctgatg acgtccttgg tgggatacat cacgctatct
     7741 acatgaacgg cggttgcttc agggccaaaa aaataactca gatcgatggc aggaagactg
     7801 tcgttggtaa cagcttgcag tatctcgggt gtgccgatgg ccgaactgta gcctgtttct
     7861 tccatacaca acagggctat atcagggcgg cacaggaagt ttatccagag gctggcggcc
     7921 ttgatattct tacaggtggt gggaatcacc cagcagtcgg cccagcagtc gctaccctcg
     7981 atgggtacaa catactgcag gttggtgttg tcgcctgcct cgtcgatagc ccatctggcg
     8041 tcgccgttcc aggttatact catccagtcc ttgccggctg acatcaggcg cttgtcgtcc
     8101 tctacatcaa aactcttcat ctgtggacgg gccgactcca gcaagtcctc gacaatagcg
     8161 atgttgcggt tggtgaggta ggcggccaac aggttgcggt tggctacgcc cgacttgatg
     8221 tcatcgtaga atgcgtagtt gataaacacg ttatagatat cgctgaacga gtctttcata
     8281 atcaccttgc cgcgatattt cgagtcgaac aggaatgccc aactgtttac ctcttcgggt
     8341 ttaacaaact tggtgttgat gagtacgcct gtgttacccc atagatagcc tacggtgtaa
     8401 tccttggcgg tgatgccctg tgcctcgccg atgtgctgta gcatgttgtc gatgaagggt
     8461 gaggtgccat gcaggtagtt aggaatgcct tgagccacga aactggtgtc gatcggggtg
     8521 agcatcttgt gcttcatcat gcgttcggcc agatattcgg gtggacagaa cacatccacc
     8581 tctgtctgct ggtcctttat catgtcgaaa cactcttcag ggtagtcgta ggttacgtag
     8641 cttaccttga taggctggcc tgtaacctgc tggtaccatt tctcaaactt ctctataacg
     8701 cctacaccaa tgtagtcgcc ccagttatat accttcagta tctgttgacg gtcctgtgcc
     8761 tgtatggcca gactgcaaca caaggcaaga atagcggttg ctagccgttt catatcgttc
     8821 ctttttttgt ttagcgctct tcgtgctcct tcatatagtc gcgtggcgac ataccgtaga
     8881 atttcttgaa tacggtagag aacgaggctg agtttgcaaa tccacatgca tacatcacct
     8941 cggtaacgtt catgccttgg ttggccagca gctgggcggc cttcttcagg cggatattgc
     9001 ggataaagtc gtgaggtgtc tggccggtaa ggtccttcat cttgcgatgc aggtgtacac
     9061 ggctgatacc aacagtatcg gcaatcatat ctacactcag gtcggagttg ttcaggttct
     9121 tgttgatgca ctccatgatg cgctccagca gcttctcgtc gggcgacttg agttcaatct
     9181 cgtcaatctg ttcctccagg ctgtcgttac gctcgtactt caggcgcagc agacggtgct
     9241 tgttaatgag gttcatgatg gtgcggcgca gaatctccat gttgaatggt ttaacgatgt
     9301 aggcatcggc accagtctcc agactctcca gtttgtcctc gtcgcggttc ttggcggtga
     9361 gcagtactac tgggatagaa ttggtgttag gattggtttt gatgcgggta cacagggtgt
     9421 taccatccat ctcgggcatc atgatatcac tcagtaccag gtcgggcttg gtgcggatta
     9481 cctcgccaag tgcctcgcga ccattggtgc aggcatgtat atcgtaatcc ttcgagagct
     9541 cgctctcaag gtagttgcga atctcctcat catcttcggc aatcaccaga gtgagcttgc
     9601 ggttgccagg tgtcatctcg ctcatcgggt taatcagctc tgtctcgggc tcctcttcca
     9661 acagcagttc gggggtgatg gtctcggcgg cctcggctgc ttcggcttcg gtaatcatct
     9721 cgtcagcatt cagatggctg ttgcccatag ggatggtaat cacaaactca cagcccttct
     9781 ccaggttgtg aacggtaatg gtaccatggt gcagctcaac cagcgaacgg gtaaggtcga
     9841 gaccgatgcc agtgcccaca taacggtcgt tgagcgtggt gggcgtctga tagaagcggt
     9901 cgaagatctt gttcatctta tcctcgggga tgccttcgcc attgtcgtag atggcgattg
     9961 tggccgattc gtcagtatga ctgatgcgaa tgcctatctc gccaccggtt ggggtgtact
    10021 tgaaagcatt cgagagtaca ttcataagta ccttatcgaa gttctggcga tctatccata
    10081 caggaatctt atcgctatcg tgttcgtaga taaacttaat ctgcttggtc ttggcctgat
    10141 tatcaaacag gtcgtagata tccttggcaa agcttaccag gttggtctca cgcattcgca
    10201 tctgcatctg acccttgtcg atctttcgca ggtccatcat ctggttaatc agactgagaa
    10261 tacgctcggc attacgacgg atggtttcgt aaactgcttt gcggctggga tcgttgtcgt
    10321 tcttgataag cgagagcaac ggtgtgagaa tcagcgtcat tggggtgcgg atctcgtgac
    10381 tcatgttcat gaagaaacgc aacttggcct cgcccatctc ttcggcatgg atatgggcct
    10441 ggaggcgcag cttatcctgc tccttatggc gacggtaaac caaatactgc catacaaaca
    10501 taccgataac catagcgtag aagaaataag cccaagccga gcggtaccac ggactgtgga
    10561 taaccaccgt gaactctctt acgggtgttt ctacgttatt gcgctcggcc ttaaccctga
    10621 atcggtaggt gccttgtggc aggtgcgaca gggtaagcac gttctcgcct ggctgcaagc
    10681 ggttgaatgg ctcgccatta atactatata aataagatat gtgttcaggg ttctcgtagg
    10741 taagggtcga gaactggatt gagaacgtgt tatcgctata gctgagttcg aaacggttgc
    10801 tggcaatgat ggtagtatcg gtaaccagat aactgcctga atgggtggca cgacttacct
    10861 gctgaccatt gatagagaag gaggtgagct caacctcagc ctcccacttg ctaggagcaa
    10921 tatggtgaga gtcgaaccac gagatacctg ctgtgccacc catggtgagg ataccatcgg
    10981 gcgacatgaa tgaggcacca tcgctgaact cgttactctg cagaccatca tccacaaaat
    11041 agttctgcca gatatcggat ttaggtgtga aacagctcag tccgtggtcg gtacctatcc
    11101 aaagacggcc ttgcaggtcg cgttcgatgg tggcaatacc gttatcggcc aaaccatcag
    11161 cacgggtata ttgctgggtt ttgtgggtac gcagatcgta gcggaacaag ccctcgttgg
    11221 taccatacca caggttaccg tcgtattcgc gggtaattct tacaggggtg ctgtagttca
    11281 gacagttcat accaaaggtg cttgtccagc tgttggcagg gatgtcgaga cagcataacc
    11341 ccatactggt ggatacatac aaacgtttgc catcgggcga cagttgaacc tgcgatacat
    11401 aatcgttggt aatgcagttc atcttcctgt tcttatcagc gcctgccttc attttgtaaa
    11461 tggccagcac acgtccgtcg ttggggtcca tcttcacaat gccatgtttc atggtaccca
    11521 accacaggta gccatcgttg cccacggcta tgtccattac aatcaggttg ggatccatgg
    11581 ggaatggtac gcggtgatac tggaaggtaa caggatcaac ccagccgata ccttcgcggt
    11641 atgtacctaa ccagatacgt cccttctggt cttcggccag cgatacgatg actgatggat
    11701 actggtcctt aaggtgctta gaggcctggc tgtagaaatc gtagcagtaa agcccgtcct
    11761 tatcggtacc cacccataca cgcttcttgc tgtccaagat aacgctgatg acgcaggctg
    11821 tacctaatat attatgggca ccaagtttat gtcccatgta gtggaagccc ttaaagctga
    11881 tgggctgcat aaagataccc ttctgcaata atccgaacca caggttgccg ctcttgtcct
    11941 cggtaataga gtaaacctta ctcataggaa ggttaacctc gagtgagaag aacgggttat
    12001 caatcagttc gggtttgcgg ggattataga gggctatacc ctgaccatcg taaccaatca
    12061 caatgttacc atcgtgggca caatagagcg atgatacggc tttagtacct gtttcggcaa
    12121 tgtgaacgaa cgtgtcgccc tgcattctga atacaccgca gttggtgcta ccggcataga
    12181 tgatgccatc ggcaccttcg cagaggcatg agaacaccac gctgggcagg ttctgcatat
    12241 ggcgcttgac ggtcttgccg ttgtatgaga tgaggcccat gtgctctgta acaatccaca
    12301 gggtacctgt acggtcctca atcatactgt taacggtgtg tatggtcgcc aaaggtccct
    12361 tctcctgata ggctgtcttc tgatccttga acttcaggat acctagacca gaggttccca
    12421 ccagtacgtc gccattggca cgctccagga agcagttggg gtaactgtga ccggcgttgc
    12481 cgttcttgtc gtacatggtg acattatgga atttggtgcc gtcccacgtc tgcagggcgc
    12541 catacatacc aaaataaaat aaaccattgc gatcttgcat catgctgttc acatagttgc
    12601 tggccagtga actgtcgtgc tcgttctctt tcttgaatac gcggaactga taaccatcgt
    12661 agcgattgat accgttacgg gtggttgtcc agatgaatcc ctcgttatca agatatactt
    12721 gtgttacaaa gctgcttgat aattgatgat cggtagtgaa gaactttccc ctttgggcga
    12781 aagcactcaa cgagagaagt gaagtagcta gagtcagtat atacttaact ttcatt
//
